thioctic acid has been researched along with Brain Edema in 8 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alpha lipoic acid is effictive in the treatment of brain edema after experimental traumatic brain injury." | 1.56 | The Effect of Alpha Lipoic Acid on Cerebrospinal Fluid Biochemistry and Brain Edema After Experimental Traumatic Brain Injury. ( Bayar, MA; Celik, H; Erdem, Y; Kul, G; Kul, H; Kurtulus, A; Tekiner, A, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Kul, H | 1 |
| Celik, H | 1 |
| Kurtulus, A | 1 |
| Tekiner, A | 1 |
| Erdem, Y | 1 |
| Kul, G | 1 |
| Bayar, MA | 1 |
| Lv, C | 2 |
| Maharjan, S | 1 |
| Wang, Q | 2 |
| Sun, Y | 2 |
| Han, X | 2 |
| Wang, S | 2 |
| Mao, Z | 2 |
| Xin, Y | 2 |
| Zhang, B | 2 |
| Wang, Y | 1 |
| Gao, A | 1 |
| Xu, X | 1 |
| Dang, B | 1 |
| You, W | 1 |
| Li, H | 1 |
| Yu, Z | 1 |
| Chen, G | 1 |
| Deng, H | 1 |
| Zuo, X | 1 |
| Zhang, J | 1 |
| Liu, X | 1 |
| Liu, L | 1 |
| Xu, Q | 1 |
| Wu, Z | 1 |
| Ji, A | 1 |
| Wei, W | 1 |
| Wang, H | 1 |
| Wu, Y | 1 |
| Ding, K | 1 |
| Li, T | 1 |
| Cong, Z | 1 |
| Xu, J | 1 |
| Zhou, M | 1 |
| Huang, L | 1 |
| Ding, H | 1 |
| Wu, H | 1 |
| Toklu, HZ | 2 |
| Hakan, T | 1 |
| Biber, N | 1 |
| Solakoğlu, S | 1 |
| Oğünç, AV | 1 |
| Sener, G | 2 |
| Erşahin, M | 1 |
| Cetinel, S | 1 |
| Yüksel, M | 1 |
| Erzik, C | 1 |
| Berkman, MZ | 1 |
| Yeğen, BC | 1 |
8 other studies available for thioctic acid and Brain Edema
| Article | Year |
|---|---|
The Effect of Alpha Lipoic Acid on Cerebrospinal Fluid Biochemistry and Brain Edema After Experimental Traumatic Brain Injury.
Topics: Animals; Antioxidants; Brain Edema; Brain Injuries, Traumatic; Cerebrospinal Fluid; Male; Rabbits; T | 2020 |
α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
Topics: Animals; Brain; Brain Edema; Cell Hypoxia; Cell Survival; Cells, Cultured; Disease Models, Animal; G | 2017 |
The Role of Alpha-Lipoic Acid in the Pathomechanism of Acute Ischemic Stroke.
Topics: Animals; Behavior, Animal; Brain Edema; Cell Line; Cyclooxygenase 2; Disease Models, Animal; Infarct | 2018 |
The Neuroprotection of Lysosomotropic Agents in Experimental Subarachnoid Hemorrhage Probably Involving the Apoptosis Pathway Triggering by Cathepsins via Chelating Intralysosomal Iron.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; Blood-Brain Barrier; Brain; Brain | 2015 |
Α‑lipoic acid protects against cerebral ischemia/reperfusion-induced injury in rats.
Topics: Animals; Antioxidants; Apoptosis; Brain Edema; Brain Ischemia; Brain-Derived Neurotrophic Factor; Ca | 2015 |
Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury.
Topics: Animals; Apoptosis; Brain Edema; Brain Injuries; Male; Mitochondria; Neurons; Oxidative Stress; Rats | 2015 |
The protective effect of alpha lipoic acid against traumatic brain injury in rats.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Edema; Brain Injuries; Glutathione; Interleukin-1b | 2009 |
Alpha lipoic acid alleviates oxidative stress and preserves blood brain permeability in rats with subarachnoid hemorrhage.
Topics: Animals; Antioxidants; Basilar Artery; Behavior, Animal; Blood-Brain Barrier; Brain Edema; DNA Fragm | 2010 |