thioctic acid has been researched along with Brain Diseases in 7 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Esin, RG | 1 |
| Khairullin, IK | 1 |
| Esin, OR | 1 |
| Habarou, F | 1 |
| Hamel, Y | 1 |
| Haack, TB | 1 |
| Feichtinger, RG | 1 |
| Lebigot, E | 1 |
| Marquardt, I | 1 |
| Busiah, K | 1 |
| Laroche, C | 1 |
| Madrange, M | 1 |
| Grisel, C | 1 |
| Pontoizeau, C | 1 |
| Eisermann, M | 1 |
| Boutron, A | 1 |
| Chrétien, D | 1 |
| Chadefaux-Vekemans, B | 1 |
| Barouki, R | 1 |
| Bole-Feysot, C | 1 |
| Nitschke, P | 1 |
| Goudin, N | 1 |
| Boddaert, N | 1 |
| Nemazanyy, I | 1 |
| Delahodde, A | 1 |
| Kölker, S | 1 |
| Rodenburg, RJ | 1 |
| Korenke, GC | 1 |
| Meitinger, T | 1 |
| Strom, TM | 1 |
| Prokisch, H | 1 |
| Rotig, A | 1 |
| Ottolenghi, C | 1 |
| Mayr, JA | 1 |
| de Lonlay, P | 1 |
| Liu, Y | 1 |
| Zhang, Q | 1 |
| Wang, L | 1 |
| Wang, H | 1 |
| Sun, T | 1 |
| Xia, H | 1 |
| Yang, Y | 1 |
| Zhang, L | 1 |
| Subramanian, VS | 1 |
| Constantinescu, AR | 1 |
| Benke, PJ | 1 |
| Said, HM | 1 |
| ALTSCHULE, MD | 1 |
| GONCZ, RM | 1 |
| HOLLIDAY, PD | 1 |
| Clayton, BE | 1 |
| Dobbs, RH | 1 |
| Patrick, AD | 1 |
| Hommes, FA | 1 |
| Polman, HA | 1 |
| Reerink, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Alpha-lipoic Acid Adjunctive Therapy in Schizophrenia: A Randomized, Double-blind, Placebo-controlled Trial[NCT03788759] | Phase 2/Phase 3 | 48 participants (Actual) | Interventional | 2019-09-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for thioctic acid and Brain Diseases
| Article | Year |
|---|---|
[Diabetic encephalopathy: current insights and potential therapeutic strategies].
Topics: Antioxidants; Brain Diseases; Diabetes Mellitus; Diabetic Neuropathies; Humans; Polyneuropathies; Th | 2021 |
Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy.
Topics: Acyltransferases; Amino Acids; Atrophy; Brain; Brain Diseases; Brain Mapping; Cells, Cultured; Energ | 2017 |
The α-lipoic acid improves high-fat diet-induced cerebral damage through inhibition of oxidative stress and inflammatory reaction.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Brain Diseases; Diet, High-Fat; Disease Models, A | 2017 |
Mutations in SLC5A6 associated with brain, immune, bone, and intestinal dysfunction in a young child.
Topics: Biotin; Bone Diseases; Brain Diseases; Cell Line, Tumor; Exons; Genome, Human; Humans; Infant; Intes | 2017 |
Carbohydrate metabolism in brain disease. XI. Effects of thioctic (alpha-lipoic) acid in chronic schizophrenia.
Topics: Brain Diseases; Carbohydrate Metabolism; Carbohydrates; Humans; Schizophrenia; Thioctic Acid; Vitami | 1959 |
Leigh's subacute necrotizing encephalopathy: clinical and biochemical study, with special reference to therapy with lipoate.
Topics: Blood Chemical Analysis; Brain Diseases; Brain Stem; Child; Child, Preschool; Clinical Enzyme Tests; | 1967 |
Leigh's encephalomyelopathy: an inborn error of gluconeogenesis.
Topics: Animals; Blood Glucose; Brain Diseases; Carbohydrate Metabolism, Inborn Errors; Carboxy-Lyases; Epin | 1968 |