thioctic acid has been researched along with Body Weight in 100 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effects of the combination of d-chiro inositol and alpha lipoic acid on menstrual cycles and insulin sensitivity in women with polycystic ovary syndrome (PCOS)." | 7.91 | Treatment with d-chiro-inositol and alpha lipoic acid in the management of polycystic ovary syndrome. ( Canu, A; Capozzi, A; Fruzzetti, F; Lello, S, 2019) |
| "Metformin or/and α-LA attenuated the severity of the DSS-induced colitis through improving the reductions in body weights, the DAI, the colonic oxidative stress markers, TNF-α, and NF-κB levels, and the morphological mucosal damage scores." | 7.88 | New insights on the modulatory roles of metformin or alpha-lipoic acid versus their combination in dextran sulfate sodium-induced chronic colitis in rats. ( Elaidy, SM; Essawy, SS; Hassan, MS; Samman, FS, 2018) |
| "We compared body weight and food intake among vehicle-, olanzapine-, and olanzapine plus ALA-treated mice, and measured hypothalamic AMP-activated protein kinase (AMPK) activity by detecting levels of Thr(172) and Ser(485/491) phosphorylation, which indicate activation and inhibition of AMPK, respectively." | 7.80 | Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine. ( Cho, HS; Jeong, J; Kim, E; Kim, H; Lee, BI; Lee, SK; Namkoong, K; Park, JY; Park, M, 2014) |
| "We evaluate the effect of supplementation, at 300 mg kg(-1) body weight (BW), with the antioxidants α-lipoic acid (AL), betaine (BT), l-carnitine (LC), and the combination of these and exercise on obesity induced by a 9 week high-fat diet (HFD) in mice." | 7.80 | The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet. ( Jang, A; Jo, C; Jung, S; Kim, D; Kim, HJ; Sung, KS, 2014) |
| "The combination of pioglitazone and α-lipoic acid has a significantly improving effect on BMI, body weight, oxidative stress levels, lipid metabolism, and menstrual status." | 4.31 | Beneficial effects of pioglitazone and α-lipoic acid in patients with polycystic ovaries syndrome. ( Hu, H; Liu, YY; Pei, Y; Sun, M; Wang, B; Wang, ZL; Zheng, J; Zhou, TT, 2023) |
| "To evaluate the effects of the combination of d-chiro inositol and alpha lipoic acid on menstrual cycles and insulin sensitivity in women with polycystic ovary syndrome (PCOS)." | 3.91 | Treatment with d-chiro-inositol and alpha lipoic acid in the management of polycystic ovary syndrome. ( Canu, A; Capozzi, A; Fruzzetti, F; Lello, S, 2019) |
| "Metformin or/and α-LA attenuated the severity of the DSS-induced colitis through improving the reductions in body weights, the DAI, the colonic oxidative stress markers, TNF-α, and NF-κB levels, and the morphological mucosal damage scores." | 3.88 | New insights on the modulatory roles of metformin or alpha-lipoic acid versus their combination in dextran sulfate sodium-induced chronic colitis in rats. ( Elaidy, SM; Essawy, SS; Hassan, MS; Samman, FS, 2018) |
| "We compared body weight and food intake among vehicle-, olanzapine-, and olanzapine plus ALA-treated mice, and measured hypothalamic AMP-activated protein kinase (AMPK) activity by detecting levels of Thr(172) and Ser(485/491) phosphorylation, which indicate activation and inhibition of AMPK, respectively." | 3.80 | Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine. ( Cho, HS; Jeong, J; Kim, E; Kim, H; Lee, BI; Lee, SK; Namkoong, K; Park, JY; Park, M, 2014) |
| "We evaluate the effect of supplementation, at 300 mg kg(-1) body weight (BW), with the antioxidants α-lipoic acid (AL), betaine (BT), l-carnitine (LC), and the combination of these and exercise on obesity induced by a 9 week high-fat diet (HFD) in mice." | 3.80 | The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet. ( Jang, A; Jo, C; Jung, S; Kim, D; Kim, HJ; Sung, KS, 2014) |
| " Body weight, food intake, fat mass, phosphorylated AMPKα (pAMPKα), and phosphorylated acetyl-CoA carboxylase (ACC) protein expression in both the hypothalamus and white adipose tissue (WAT) as well as plasma leptin and adiponectin levels were measured in rats after either Ovx or sham operations." | 3.77 | Reciprocal effects of α-lipoic acid on adenosine monophosphate-activated protein kinase activity in obesity induced by ovariectomy in rats. ( Cheng, PY; Lam, KK; Lee, YM; Peng, JC; Yen, MH, 2011) |
| "There are numerous trials reported the effect of alpha-lipoic acid (ALA) on obesity measurements; while no summarised dose-response meta-analysis is available to address the effects of dose and duration of ALA supplementation on obesity measurements." | 2.66 | Alpha-lipoic acid supplementation significantly reduces the risk of obesity in an updated systematic review and dose response meta-analysis of randomised placebo-controlled clinical trials. ( Abbasalizad Farhangi, M; Vajdi, M, 2020) |
| "Correlation between type 2 diabetes and other abnormalities such as obesity with redox balance disturbance was analyzed in many reports." | 1.72 | The Effect of α-Lipoic Acid on Oxidative Stress in Adipose Tissue of Rats with Obesity-Induced Insulin Resistance. ( Chabowski, A; Dajnowicz-Brzezik, P; Maciejczyk, M; Zalewska, A; Żebrowska, E, 2022) |
| "Scopolamine- induced memory loss is used to study new drug discovery in Alzheimer's disease (AD) pathogenesis." | 1.62 | Alpha lipoic acid ameliorates scopolamine induced memory deficit and neurodegeneration in the cerebello-hippocampal cortex. ( Adewumi, AE; Memudu, AE, 2021) |
| "Diabetic neuropathies are a family of nerve disorders caused by diabetes." | 1.35 | Coenzyme Q(10) and alpha-lipoic acid supplementation in diabetic rats: conduction velocity distributions. ( Ayaz, M; Gokbel, H; Okudan, N; Tuncer, S, 2008) |
| "Corticosteroid therapy for Duchenne muscular dystrophy is effective but associated with long-term side effects." | 1.33 | Nutritional therapy improves function and complements corticosteroid intervention in mdx mice. ( Bourgeois, JM; Devries, MC; Payne, ET; Rodriguez, MC; Tarnopolsky, MA; Yasuda, N; Yousuf, J, 2006) |
| " The only notable finding in rats of both sexes dosed at 180 mg/kg bw/day was a reduction in food intake relative to the controls and a concomitant decrease in body weight." | 1.33 | Long-term safety of alpha-lipoic acid (ALA) consumption: A 2-year study. ( Cremer, DR; Lynch, B; Rabeler, R; Roberts, A, 2006) |
| " ALA was not acutely toxic to rats (LD(50)>2000mg/kg bw, OECD method 425)." | 1.33 | Safety evaluation of alpha-lipoic acid (ALA). ( Cremer, DR; Lynch, B; Rabeler, R; Roberts, A, 2006) |
| " The racemate of lipoic acid at high dosage (350 mg/kg body weight) reduced the life span significantly." | 1.30 | Influence of selegiline and lipoic acid on the life expectancy of immunosuppressed mice. ( Ackermann, H; Freisleben, HJ; Lehr, F; Neeb, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (5.00) | 18.7374 |
| 1990's | 9 (9.00) | 18.2507 |
| 2000's | 38 (38.00) | 29.6817 |
| 2010's | 41 (41.00) | 24.3611 |
| 2020's | 7 (7.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dajnowicz-Brzezik, P | 1 |
| Żebrowska, E | 1 |
| Maciejczyk, M | 1 |
| Zalewska, A | 1 |
| Chabowski, A | 1 |
| Pei, Y | 1 |
| Liu, YY | 1 |
| Sun, M | 1 |
| Zheng, J | 1 |
| Zhou, TT | 1 |
| Wang, B | 1 |
| Hu, H | 1 |
| Wang, ZL | 1 |
| Takenouchi, Y | 1 |
| Tsuboi, K | 1 |
| Ohsuka, K | 1 |
| Nobe, K | 1 |
| Ohtake, K | 1 |
| Okamoto, Y | 1 |
| Kasono, K | 1 |
| Vajdi, M | 1 |
| Abbasalizad Farhangi, M | 1 |
| Kim, JH | 1 |
| Jeong, BK | 1 |
| Jang, SJ | 1 |
| Yun, JW | 1 |
| Jung, MH | 1 |
| Kang, KM | 1 |
| Kim, TG | 1 |
| Woo, SH | 1 |
| Behnamifar, A | 1 |
| Rahimi, S | 1 |
| Karimi Torshizi, MA | 1 |
| Sharafi, M | 1 |
| Grimes, JL | 1 |
| Memudu, AE | 1 |
| Adewumi, AE | 1 |
| Kravchenko, LV | 1 |
| Aksenov, IV | 1 |
| Nikitin, NS | 1 |
| Guseva, GV | 1 |
| Avrenyeva, LI | 1 |
| Trusov, NV | 1 |
| Balakina, AS | 1 |
| Tutelyan, VA | 1 |
| Liu, Y | 1 |
| Zhang, Q | 1 |
| Wang, L | 1 |
| Wang, H | 3 |
| Sun, T | 1 |
| Xia, H | 1 |
| Yang, Y | 1 |
| Zhang, L | 1 |
| Maiztegui, B | 1 |
| Román, CL | 1 |
| Gagliardino, JJ | 1 |
| Flores, LE | 1 |
| Samman, FS | 1 |
| Elaidy, SM | 1 |
| Essawy, SS | 1 |
| Hassan, MS | 1 |
| Zhang, GW | 1 |
| Wan, XX | 1 |
| Wan, CC | 1 |
| Li, KQ | 1 |
| Li, YZ | 1 |
| Weng, ZQ | 1 |
| Shang, XJ | 1 |
| Fruzzetti, F | 1 |
| Capozzi, A | 1 |
| Canu, A | 1 |
| Lello, S | 1 |
| Feng, B | 1 |
| Yan, XF | 1 |
| Xue, JL | 1 |
| Xu, L | 1 |
| Baky, NA | 1 |
| Faddah, LM | 1 |
| Al-Rasheed, NM | 2 |
| Fatani, AJ | 1 |
| Parveen, R | 1 |
| Asghar, A | 1 |
| Anjum, FM | 2 |
| Khan, MI | 2 |
| Arshad, MS | 2 |
| Yasmeen, A | 1 |
| Yi, X | 1 |
| Pashaj, A | 1 |
| Xia, M | 1 |
| Moreau, R | 1 |
| Kathirvel, E | 1 |
| Morgan, K | 1 |
| French, SW | 1 |
| Morgan, TR | 1 |
| Wongmekiat, O | 1 |
| Leelarungrayub, D | 1 |
| Thamprasert, K | 1 |
| Shahid, M | 1 |
| Akhtar, S | 1 |
| Sohaib, M | 1 |
| Hamano, Y | 3 |
| Kim, H | 1 |
| Park, M | 1 |
| Lee, SK | 1 |
| Jeong, J | 1 |
| Namkoong, K | 1 |
| Cho, HS | 1 |
| Park, JY | 4 |
| Lee, BI | 1 |
| Kim, E | 1 |
| Jang, A | 1 |
| Kim, D | 1 |
| Sung, KS | 1 |
| Jung, S | 1 |
| Kim, HJ | 1 |
| Jo, C | 1 |
| Jana, K | 1 |
| Dutta, A | 1 |
| Chakraborty, P | 1 |
| Manna, I | 1 |
| Firdaus, SB | 1 |
| Bandyopadhyay, D | 1 |
| Chattopadhyay, R | 1 |
| Chakravarty, B | 1 |
| Okanović, A | 1 |
| Prnjavorac, B | 1 |
| Jusufović, E | 1 |
| Sejdinović, R | 1 |
| Behling, CS | 1 |
| Andrade, AS | 1 |
| Putti, JS | 1 |
| Mahl, CD | 1 |
| Hackenhaar, FS | 1 |
| da Silva, AC | 1 |
| e Silva, MN | 1 |
| Salomon, TB | 1 |
| Dos Santos, CE | 1 |
| Dias, JF | 1 |
| Benfato, MS | 1 |
| Radzki, RP | 1 |
| Bienko, M | 1 |
| Wolski, D | 1 |
| Lis, A | 1 |
| Radzka, A | 1 |
| Güleş, Ö | 1 |
| Eren, Ü | 1 |
| Derosa, G | 1 |
| D'Angelo, A | 1 |
| Romano, D | 1 |
| Maffioli, P | 1 |
| Hall, JA | 1 |
| Yerramilli, M | 2 |
| Obare, E | 1 |
| Panickar, KS | 1 |
| Bobe, G | 1 |
| Jewell, DE | 1 |
| Al-Matubsi, HY | 1 |
| Oriquat, GA | 1 |
| Abu-Samak, M | 1 |
| Al Hanbali, OA | 1 |
| Salim, MD | 1 |
| Li, N | 1 |
| Yan, W | 1 |
| Hu, X | 1 |
| Huang, Y | 1 |
| Wang, F | 1 |
| Zhang, W | 1 |
| Wang, Q | 1 |
| Wang, X | 1 |
| Sun, K | 1 |
| Ayaz, M | 1 |
| Tuncer, S | 1 |
| Okudan, N | 1 |
| Gokbel, H | 1 |
| Luz, J | 1 |
| Zemdegs, JC | 1 |
| Amaral, LS | 1 |
| Gupte, AA | 1 |
| Bomhoff, GL | 1 |
| Morris, JK | 1 |
| Gorres, BK | 1 |
| Geiger, PC | 1 |
| Timmers, S | 1 |
| de Vogel-van den Bosch, J | 1 |
| Towler, MC | 1 |
| Schaart, G | 1 |
| Moonen-Kornips, E | 1 |
| Mensink, RP | 1 |
| Hesselink, MK | 1 |
| Hardie, DG | 1 |
| Schrauwen, P | 1 |
| Carbonelli, MG | 1 |
| Di Renzo, L | 1 |
| Bigioni, M | 1 |
| Di Daniele, N | 1 |
| De Lorenzo, A | 1 |
| Fusco, MA | 1 |
| Tabassum, H | 1 |
| Parvez, S | 1 |
| Pasha, ST | 1 |
| Banerjee, BD | 1 |
| Raisuddin, S | 1 |
| Dixit, S | 1 |
| Dhar, P | 1 |
| Mehra, RD | 1 |
| Koh, EH | 2 |
| Lee, WJ | 2 |
| Lee, SA | 1 |
| Kim, EH | 1 |
| Cho, EH | 1 |
| Jeong, E | 1 |
| Kim, DW | 1 |
| Kim, MS | 3 |
| Park, KG | 1 |
| Lee, HJ | 1 |
| Lee, IK | 2 |
| Lim, S | 1 |
| Jang, HC | 1 |
| Lee, KH | 1 |
| Lee, KU | 3 |
| Ghibu, S | 1 |
| Delemasure, S | 1 |
| Richard, C | 1 |
| Guilland, JC | 1 |
| Martin, L | 1 |
| Gambert, S | 1 |
| Rochette, L | 1 |
| Vergely, C | 1 |
| Fernández-Galilea, M | 1 |
| Pérez-Matute, P | 3 |
| Prieto-Hontoria, P | 1 |
| Martínez, JA | 3 |
| Moreno-Aliaga, MJ | 3 |
| Cheng, PY | 1 |
| Lee, YM | 1 |
| Yen, MH | 1 |
| Peng, JC | 1 |
| Lam, KK | 1 |
| El-Beshbishy, HA | 1 |
| Bahashwan, SA | 1 |
| Aly, HA | 1 |
| Fakher, HA | 1 |
| Deiuliis, JA | 1 |
| Kampfrath, T | 1 |
| Ying, Z | 1 |
| Maiseyeu, A | 1 |
| Rajagopalan, S | 1 |
| El Midaoui, A | 4 |
| Lungu, C | 1 |
| Wu, L | 2 |
| Robillard, C | 1 |
| Deblois, D | 1 |
| Couture, R | 3 |
| Yeni, D | 1 |
| Fidan, AF | 1 |
| Ciğerci, IH | 1 |
| Konuk, M | 1 |
| Avdatek, F | 1 |
| Gündoğan, M | 1 |
| Valdecantos, MP | 2 |
| González-Muniesa, P | 2 |
| Prieto-Hontoria, PL | 2 |
| Kondo, H | 1 |
| Takeuchi, S | 1 |
| Togari, A | 1 |
| Walter, A | 1 |
| Krämer, K | 1 |
| Most, E | 1 |
| Pallauf, J | 1 |
| Obrosova, IG | 2 |
| Fathallah, L | 2 |
| Liu, E | 1 |
| Nourooz-Zadeh, J | 1 |
| Midaoui, AE | 1 |
| Elimadi, A | 1 |
| Haddad, PS | 1 |
| de Champlain, J | 4 |
| JOWSEY, JR | 1 |
| BLAKELY, RM | 1 |
| MACGREGOR, HI | 1 |
| LOMBARDI, D | 1 |
| Vasdev, S | 1 |
| Gill, V | 1 |
| Longerich, L | 1 |
| Parai, S | 1 |
| Gadag, V | 1 |
| Thirunavukkarasu, V | 1 |
| Anitha Nandhini, AT | 1 |
| Anuradha, CV | 1 |
| Lee, CK | 1 |
| Pugh, TD | 1 |
| Klopp, RG | 1 |
| Edwards, J | 1 |
| Allison, DB | 1 |
| Weindruch, R | 1 |
| Prolla, TA | 1 |
| Saengsirisuwan, V | 3 |
| Perez, FR | 2 |
| Sloniger, JA | 1 |
| Maier, T | 1 |
| Henriksen, EJ | 5 |
| Sivaprasad, TR | 1 |
| Malarkodi, SP | 1 |
| Varalakshmi, P | 2 |
| Namkoong, C | 1 |
| Jang, PG | 1 |
| Ryu, JW | 1 |
| Song, HS | 1 |
| Yun, JY | 1 |
| Namgoong, IS | 1 |
| Ha, J | 1 |
| Park, IS | 1 |
| Viollet, B | 1 |
| Youn, JH | 2 |
| Lee, HK | 1 |
| Wollin, SD | 1 |
| Wang, Y | 1 |
| Kubow, S | 1 |
| Jones, PJ | 1 |
| Kumar, MS | 1 |
| Prashanth, KV | 1 |
| Al Ghafli, MH | 1 |
| Padmanabhan, R | 1 |
| Kataya, HH | 1 |
| Berg, B | 1 |
| Selvakumar, E | 1 |
| Prahalathan, C | 1 |
| Mythili, Y | 1 |
| Song, KH | 1 |
| Koh, JM | 1 |
| Kim, HS | 1 |
| Youn, JY | 1 |
| Park, HS | 1 |
| Jesudason, EP | 1 |
| Masilamoni, JG | 1 |
| Jesudoss, KS | 1 |
| Jayakumar, R | 1 |
| Petcu, M | 2 |
| Ongali, B | 2 |
| Lateef, H | 1 |
| Aslam, MN | 1 |
| Stevens, MJ | 2 |
| Varani, J | 1 |
| Rodi, D | 1 |
| Neugebauer, W | 1 |
| Payne, ET | 1 |
| Yasuda, N | 1 |
| Bourgeois, JM | 1 |
| Devries, MC | 1 |
| Rodriguez, MC | 1 |
| Yousuf, J | 1 |
| Tarnopolsky, MA | 1 |
| Shen, QW | 1 |
| Jones, CS | 1 |
| Kalchayanand, N | 1 |
| Zhu, MJ | 1 |
| Du, M | 1 |
| Cremer, DR | 2 |
| Rabeler, R | 2 |
| Roberts, A | 2 |
| Lynch, B | 2 |
| Zhang, WJ | 1 |
| Bird, KE | 1 |
| McMillen, TS | 1 |
| LeBoeuf, RC | 1 |
| Hagen, TM | 1 |
| Frei, B | 1 |
| Huang, EA | 1 |
| Gitelman, SE | 1 |
| Künstler, K | 1 |
| Jacob, S | 2 |
| Schiemann, AL | 1 |
| Simon, I | 1 |
| Clancy, DE | 1 |
| Tritschler, HJ | 4 |
| Jung, WI | 1 |
| Augustin, HJ | 1 |
| Dietze, GJ | 2 |
| Podda, M | 1 |
| Ulrich, H | 3 |
| Packer, L | 1 |
| Streeper, RS | 1 |
| Fogt, DL | 1 |
| Hokama, JY | 1 |
| Ziegler, D | 1 |
| Schatz, H | 1 |
| Conrad, F | 1 |
| Gries, FA | 1 |
| Reichel, G | 1 |
| Freisleben, HJ | 1 |
| Neeb, A | 1 |
| Lehr, F | 1 |
| Ackermann, H | 1 |
| Cameron, NE | 2 |
| Cotter, MA | 2 |
| Horrobin, DH | 1 |
| Keegan, A | 1 |
| Sugawara, S | 1 |
| Kamota, Y | 1 |
| Nagai, E | 1 |
| Greene, DA | 2 |
| Obrosova, I | 1 |
| Cao, X | 1 |
| Van Huysen, C | 1 |
| Biessels, GJ | 1 |
| Smale, S | 1 |
| Duis, SE | 1 |
| Kamal, A | 1 |
| Gispen, WH | 1 |
| Yamamoto, H | 1 |
| Watanabe, T | 1 |
| Mizuno, H | 1 |
| Endo, K | 1 |
| Fukushige, J | 1 |
| Hosokawa, T | 1 |
| Kazusaka, A | 1 |
| Fujita, S | 1 |
| Clark, WM | 1 |
| Rinker, LG | 1 |
| Lessov, NS | 1 |
| Lowery, SL | 1 |
| Cipolla, MJ | 1 |
| Kinnick, TR | 2 |
| Schmit, MB | 1 |
| Takaoka, M | 1 |
| Kobayashi, Y | 1 |
| Yuba, M | 1 |
| Ohkita, M | 1 |
| Matsumura, Y | 1 |
| Andreassen, OA | 1 |
| Ferrante, RJ | 1 |
| Dedeoglu, A | 1 |
| Beal, MF | 1 |
| Koçak, G | 1 |
| Karasu, C | 1 |
| Segermann, J | 1 |
| Hotze, A | 1 |
| Rao, GS | 1 |
| Fuke, H | 1 |
| Iwanami, K | 1 |
| Watanabe, N | 1 |
| Kumada, S | 1 |
| Halikowski, B | 1 |
| Kucharska, K | 1 |
| Sancewicz-Pach, K | 1 |
| Sikorska, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Alpha Lipoic Acid on the Incidence and Severity of Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients[NCT05023863] | Phase 2/Phase 3 | 70 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis[NCT04750135] | Phase 2 | 40 participants (Anticipated) | Interventional | 2021-02-07 | Not yet recruiting | ||
| The Effect of Alpha-Lipoic Acid on the Clinical Outcome of Patients With Sepsis[NCT05808946] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2023-03-10 | Recruiting | ||
| Dose Finding and Tolerability Study of Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Peripheral Neuropathy[NCT01313117] | Phase 1/Phase 2 | 9 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01313117)
Timeframe: 4 months
| Intervention | participants (Number) |
|---|---|
| Alpha Lipoic Acid | 9 |
Based on acceptable adverse event (AE) profile and continual reassessment method dose escalation. (NCT01313117)
Timeframe: 4 months
| Intervention | mg (Number) |
|---|---|
| Alpha Lipoic Acid | 500 |
(NCT01313117)
Timeframe: 4 months
| Intervention | participants (Number) |
|---|---|
| Alpha Lipoic Acid | 7 |
1 review available for thioctic acid and Body Weight
| Article | Year |
|---|---|
Alpha-lipoic acid supplementation significantly reduces the risk of obesity in an updated systematic review and dose response meta-analysis of randomised placebo-controlled clinical trials.
Topics: Antioxidants; Body Mass Index; Body Weight; Dietary Supplements; Female; Humans; Male; Obesity; Thio | 2020 |
9 trials available for thioctic acid and Body Weight
| Article | Year |
|---|---|
Effects of dietary alpha-lipoic acid supplementation on the seminal parameters and fertility potential in aging broiler breeder roosters.
Topics: Aging; Animal Feed; Animals; Body Weight; Chickens; Dietary Supplements; Female; Fertility; Insemina | 2021 |
A Clinical Trial about a Food Supplement Containing α-Lipoic Acid on Oxidative Stress Markers in Type 2 Diabetic Patients.
Topics: Adult; Biomarkers; Blood Glucose; Body Mass Index; Body Weight; C-Reactive Protein; Carnosine; Diabe | 2016 |
Nutritional Interventions that Slow the Age-Associated Decline in Renal Function in a Canine Geriatric Model for Elderly Humans.
Topics: Absorptiometry, Photon; Aged; Aging; Animals; Arginine; Biomarkers; Body Weight; Carnitine; Cross-Se | 2016 |
Effects of oral α-lipoic acid administration on body weight in overweight or obese subjects: a crossover randomized, double-blind, placebo-controlled trial.
Topics: Adult; Antioxidants; Body Weight; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Mid | 2017 |
Effects of alpha-lipoic Acid on body weight in obese subjects.
Topics: Adult; Body Weight; Double-Blind Method; Female; Humans; Male; Obesity; Thioctic Acid | 2011 |
Alleviative effects of α-lipoic acid supplementation on acute heat stress-induced thermal panting and the level of plasma nonesterified fatty acids in hypothyroid broiler chickens.
Topics: Animal Feed; Animals; Body Weight; Chickens; Diet; Dietary Supplements; Fatty Acids, Nonesterified; | 2012 |
The effect of oral alpha-lipoic acid on oxidative stress in adolescents with type 1 diabetes mellitus.
Topics: Administration, Oral; Adolescent; Age of Onset; Body Mass Index; Body Weight; Child; Delayed-Action | 2008 |
Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid.
Topics: Aged; Aging; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; | 1995 |
Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie.
Topics: Autonomic Nervous System Diseases; Blood Pressure; Body Weight; Confounding Factors, Epidemiologic; | 1997 |
90 other studies available for thioctic acid and Body Weight
| Article | Year |
|---|---|
The Effect of α-Lipoic Acid on Oxidative Stress in Adipose Tissue of Rats with Obesity-Induced Insulin Resistance.
Topics: Adipose Tissue; Animals; Antioxidants; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Insul | 2022 |
Beneficial effects of pioglitazone and α-lipoic acid in patients with polycystic ovaries syndrome.
Topics: Animals; Body Weight; Female; Humans; Insulin; Mice; Pioglitazone; Polycystic Ovary Syndrome; Thioct | 2023 |
Chronic Treatment with α-Lipoic Acid Improves Endothelium-Dependent Vasorelaxation of Aortas in High-Fat Diet-Fed Mice.
Topics: Animals; Antioxidants; Aorta; Blood Glucose; Body Weight; Diet, High-Fat; Dietary Supplements; Dose- | 2019 |
Alpha-Lipoic Acid Ameliorates Radiation-Induced Salivary Gland Injury by Preserving Parasympathetic Innervation in Rats.
Topics: Animals; Body Weight; Male; Organ Size; Radiation Injuries, Experimental; Rats, Sprague-Dawley; Sali | 2020 |
Alpha lipoic acid ameliorates scopolamine induced memory deficit and neurodegeneration in the cerebello-hippocampal cortex.
Topics: Animals; Astrocytes; Body Weight; Brain; Cerebellum; Hippocampus; Male; Memory Disorders; Neurodegen | 2021 |
Lipoic Acid Exacerbates Oxidative Stress and Lipid Accumulation in the Liver of Wistar Rats Fed a Hypercaloric Choline-Deficient Diet.
Topics: Animals; Biomarkers; Body Weight; Choline; Diet; Feeding Behavior; Lipid Metabolism; Liver; Male; Or | 2021 |
The α-lipoic acid improves high-fat diet-induced cerebral damage through inhibition of oxidative stress and inflammatory reaction.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Brain Diseases; Diet, High-Fat; Disease Models, A | 2017 |
Impaired endocrine-metabolic homeostasis: underlying mechanism of its induction by unbalanced diet.
Topics: Animals; Apoptosis; Body Weight; Dietary Sucrose; Eating; Insulin Secretion; Insulin-Secreting Cells | 2018 |
New insights on the modulatory roles of metformin or alpha-lipoic acid versus their combination in dextran sulfate sodium-induced chronic colitis in rats.
Topics: Animals; Antioxidants; Body Weight; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Male; M | 2018 |
[Lipoic acid protects spermatogenesis in male rats with ornidazole-induced oligoasthenozoospermia].
Topics: Animals; Antioxidants; Asthenozoospermia; Body Weight; Epididymis; Male; Oligospermia; Ornidazole; R | 2018 |
Treatment with d-chiro-inositol and alpha lipoic acid in the management of polycystic ovary syndrome.
Topics: Adolescent; Adult; Body Mass Index; Body Weight; Drug Therapy, Combination; Estradiol; Female; Folli | 2019 |
The protective effects of α-lipoic acid on kidneys in type 2 diabetic Goto-Kakisaki rats via reducing oxidative stress.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glu | 2013 |
Induction of inflammation, DNA damage and apoptosis in rat heart after oral exposure to zinc oxide nanoparticles and the cardioprotective role of α-lipoic acid and vitamin E.
Topics: Animals; Apoptosis; Body Weight; Calcium; Caspase 3; Comet Assay; DNA Damage; Heart; Inflammation; N | 2013 |
Selective deposition of dietary α-lipoic acid in mitochondrial fraction and its synergistic effect with α-tocoperhol acetate on broiler meat oxidative stability.
Topics: alpha-Tocopherol; Animal Feed; Animals; Antioxidants; Body Weight; Chickens; Dietary Supplements; Dr | 2013 |
Reversal of obesity-induced hypertriglyceridemia by (R)-α-lipoic acid in ZDF (fa/fa) rats.
Topics: Animals; Body Weight; Fatty Acids; Gene Expression Regulation; Hypertriglyceridemia; Insulin; Ketone | 2013 |
Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease.
Topics: Acetylcarnitine; Adipose Tissue; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransfe | 2013 |
Alpha-lipoic acid attenuates renal injury in rats with obstructive nephropathy.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Creatinine; Glutathione; Kidney; Kidney Dis | 2013 |
Wheat germ oil enrichment in broiler feed with α-lipoic acid to enhance the antioxidant potential and lipid stability of meat.
Topics: alpha-Tocopherol; Animal Feed; Animals; Antioxidants; Biphenyl Compounds; Body Weight; Chickens; Die | 2013 |
Effects of α-lipoic acid supplementation on sexual difference of growth performance, heat exposure-induced metabolic response and lipid peroxidation of raw meat in broiler chickens.
Topics: Animals; Antioxidants; Body Composition; Body Weight; Chickens; Dietary Supplements; Female; Hot Tem | 2014 |
Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Antipsychotic Agents; Benzodiazepines; | 2014 |
The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet.
Topics: Adipocytes; Animals; Antioxidants; Betaine; Blood Glucose; Body Weight; Carnitine; Cholesterol; Diet | 2014 |
Alpha-lipoic acid and N-acetylcysteine protects intensive swimming exercise-mediated germ-cell depletion, pro-oxidant generation, and alteration of steroidogenesis in rat testis.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Body Weight; Corticosterone; Eating; Exercise Tes | 2014 |
Alpha-lipoic acid reduces body weight and regulates triglycerides in obese patients with diabetes mellitus.
Topics: Body Weight; Cholesterol; Diabetes Mellitus, Type 2; Female; Humans; Male; Metformin; Middle Aged; O | 2015 |
Treatment of oxidative stress in brain of ovariectomized rats with omega-3 and lipoic acid.
Topics: Animals; Antioxidants; Body Weight; Brain; Enzymes; Estrogens; Fatty Acids, Omega-3; Female; Metals; | 2015 |
Lipoic acid stimulates bone formation in ovariectomized rats in a dose-dependent manner.
Topics: Animals; Body Composition; Body Weight; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Col | 2016 |
Protective role of alpha lipoic acid against polychlorobiphenyl (Aroclor 1254)-induced testicular toxicity in rats.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Body Weight; Chlorodiphenyl (54% Chlorine); Hem | 2016 |
Effects of Lipoic Acid Supplementation on Activities of Cyclooxygenases and Levels of Prostaglandins E
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dinoprost; Dinoprostone; Disea | 2016 |
Coenzyme Q(10) and alpha-lipoic acid supplementation in diabetic rats: conduction velocity distributions.
Topics: Action Potentials; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimenta | 2008 |
Chronic lipoic acid treatment worsens energy imbalances in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Body Composition; Body Weight; Diabetes Mellitus, Experimental; Eating; Ener | 2009 |
Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Blotting, Western; Body Weight; Cells, | 2009 |
Prevention of high-fat diet-induced muscular lipid accumulation in rats by alpha lipoic acid is not mediated by AMPK activation.
Topics: Absorption; Adult; AMP-Activated Protein Kinases; Animals; Body Composition; Body Weight; Dietary Fa | 2010 |
Alpha-lipoic acid supplementation: a tool for obesity therapy?
Topics: Adolescent; Adult; Antioxidants; Blood Pressure; Body Mass Index; Body Weight; Dietary Supplements; | 2010 |
Protective effect of lipoic acid against methotrexate-induced oxidative stress in liver mitochondria.
Topics: Animals; Body Weight; DNA; Folic Acid Antagonists; Free Radicals; Glutathione; Glutathione Peroxidas | 2010 |
Protective role of exogenous α-lipoic acid (ALA) on hippocampal antioxidant status and memory function in rat pups exposed to sodium arsenite during the early post-natal period.
Topics: Animals; Animals, Newborn; Arsenites; Body Weight; Environmental Pollutants; Female; Glutathione; Hi | 2011 |
General oxidative stress during doxorubicin-induced cardiotoxicity in rats: absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Ascitic Fluid; Ascorbic Acid; Body Weight; Cardi | 2012 |
Effects of lipoic acid on apelin in 3T3-L1 adipocytes and in high-fat fed rats.
Topics: 3T3-L1 Cells; Adipocytes, White; Animals; Apelin; Blood Glucose; Body Weight; Chromones; Diet, High- | 2011 |
Reciprocal effects of α-lipoic acid on adenosine monophosphate-activated protein kinase activity in obesity induced by ovariectomy in rats.
Topics: Acetyl-CoA Carboxylase; Adiponectin; Adipose Tissue; Animals; Body Weight; Cyclic AMP-Dependent Prot | 2011 |
Abrogation of cisplatin-induced nephrotoxicity in mice by alpha lipoic acid through ameliorating oxidative stress and enhancing gene expression of antioxidant enzymes.
Topics: Animals; Antineoplastic Agents; Antioxidants; Body Weight; Cisplatin; Cytoprotection; Gene Expressio | 2011 |
Lipoic acid attenuates innate immune infiltration and activation in the visceral adipose tissue of obese insulin resistant mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Blood Glucose; Blood Vessels; Body Weight; | 2011 |
Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats.
Topics: Animals; Aorta; Blood Glucose; Blood Pressure; Body Weight; Dietary Supplements; Fatty Acids, Nonest | 2011 |
Effect of α-lipoic acid on sperm quality, reproductive tract measures in thinner exposed rats.
Topics: Animals; Body Weight; Genitalia, Male; Male; Organ Size; Placebos; Rats; Rats, Sprague-Dawley; Solve | 2012 |
Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3.
Topics: Animals; Antioxidants; Blotting, Western; Body Weight; Diet, High-Fat; Disease Models, Animal; Fatty | 2012 |
Lipoic acid administration prevents nonalcoholic steatosis linked to long-term high-fat feeding by modulating mitochondrial function.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Body Weight; Citric Acid Cycle; Diet, High-Fat; Enzy | 2012 |
β-Adrenergic signaling stimulates osteoclastogenesis via reactive oxygen species.
Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Body Weight; Bone Marrow Cells; Cell Line; Isoprote | 2013 |
Zinc availability from zinc lipoate and zinc sulfate in growing rats.
Topics: Alkaline Phosphatase; Animals; Body Weight; Femur; Liver; Male; Metallothionein; Phytic Acid; Rats; | 2002 |
Early oxidative stress in the diabetic kidney: effect of DL-alpha-lipoic acid.
Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus; F2-Isoprostanes; | 2003 |
Lipoic acid prevents hypertension, hyperglycemia, and the increase in heart mitochondrial superoxide production.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Glucose; Glycat | 2003 |
Effect of thioctic acid on gain in body-weight by turkey poults.
Topics: Animals; Body Weight; Meat; Poultry; Thioctic Acid; Turkey; Turkeys | 1959 |
[Action of thioctic acid and reserpine on weight increase in the chick].
Topics: Animals; Body Weight; Body Weights and Measures; Chickens; Reserpine; Thioctic Acid; Weight Gain | 1962 |
Salt-induced hypertension in WKY rats: prevention by alpha-lipoic acid supplementation.
Topics: Aldehydes; Animals; Antioxidants; Blood Pressure; Body Weight; Calcium; Cytosol; Dietary Supplements | 2003 |
Lipoic acid restores antioxidant system in tissues of hyperinsulinaemic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Fructose; Insulin; Insulin Resistance; Kidney; Li | 2003 |
The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice.
Topics: Algorithms; Animals; Antioxidants; Body Weight; Caloric Restriction; Coenzymes; Complement System Pr | 2004 |
Interactions of exercise training and alpha-lipoic acid on insulin signaling in skeletal muscle of obese Zucker rats.
Topics: Animals; Antioxidants; Biological Transport; Body Weight; Female; Glucose; Glucose Transporter Type | 2004 |
Therapeutic efficacy of lipoic acid in combination with dimercaptosuccinic acid against lead-induced renal tubular defects and on isolated brush-border enzyme activities.
Topics: 5-Aminolevulinate Synthetase; Animals; Antioxidants; Biomarkers; Body Weight; Chelating Agents; Dise | 2004 |
Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase.
Topics: Animals; Anti-Obesity Agents; Body Weight; Cyclic AMP-Dependent Protein Kinases; Eating; Energy Meta | 2004 |
Effects of a medium chain triglyceride oil mixture and alpha-lipoic acid diet on body composition, antioxidant status, and plasma lipid levels in the Golden Syrian hamster.
Topics: Animals; Antioxidants; Body Composition; Body Weight; Cholesterol; Cholesterol, Dietary; Cholesterol | 2004 |
alpha-Lipoic acid ameliorates altered colonic contractility and intestinal transit in STZ-diabetic rats.
Topics: Acetylcholine; Animals; Antioxidants; Body Weight; Colon; Diabetes Mellitus, Experimental; Female; I | 2004 |
Effects of alpha-lipoic acid supplementation on maternal diabetes-induced growth retardation and congenital anomalies in rat fetuses.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Bone Development; Diabetes Mellitus, Experimental | 2004 |
Protective effect of DL-alpha-lipoic acid in cyclophosphamide induced oxidative injury in rat testis.
Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Body Weight; Cyclophosphamide; Disease Mod | 2004 |
alpha-Lipoic acid prevents diabetes mellitus in diabetes-prone obese rats.
Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Type 1; Disease Susceptibility; Male; Obesity | 2005 |
The protective role of DL-alpha-lipoic acid in the oxidative vulnerability triggered by Abeta-amyloid vaccination in mice.
Topics: Adenosine Triphosphatases; Amyloid beta-Peptides; Animals; Antioxidants; Astrocytes; Body Weight; Br | 2005 |
Effects of alpha-lipoic acid on kinin B1 and B2 receptor binding sites in the spinal cord of chronically angiotensin-treated rats.
Topics: Angiotensin II; Animals; Binding Sites; Blood Glucose; Blood Pressure; Body Weight; Chronic Disease; | 2005 |
Pretreatment of diabetic rats with lipoic acid improves healing of subsequently-induced abrasion wounds.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Endothelial Cells; Fibroblasts | 2005 |
Increases of spinal kinin receptor binding sites in two rat models of insulin resistance.
Topics: Animals; Binding Sites; Blood Glucose; Blood Pressure; Body Weight; Glucose; Insulin; Insulin Resist | 2005 |
Nutritional therapy improves function and complements corticosteroid intervention in mdx mice.
Topics: Animals; Body Weight; Creatine Kinase; Creatinine; Dietary Supplements; Linoleic Acid; Mice; Mice, I | 2006 |
Effect of dietary alpha-lipoic acid on growth, body composition, muscle pH, and AMP-activated protein kinase phosphorylation in mice.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Body Composition; Body Weight; Dietary Fats; | 2005 |
Long-term safety of alpha-lipoic acid (ALA) consumption: A 2-year study.
Topics: Administration, Oral; Animals; Antioxidants; Body Weight; Carcinogenicity Tests; Dose-Response Relat | 2006 |
Safety evaluation of alpha-lipoic acid (ALA).
Topics: Animals; Antioxidants; Behavior, Animal; Body Weight; Drug-Related Side Effects and Adverse Reaction | 2006 |
Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Body Weight; Cholesterol; Dietary Supplements; Disease | 2008 |
[The influence of thioctic acid on the growth of Ehrlich ascites carcinoma (author's transl)].
Topics: Animals; Body Weight; Carcinoma, Ehrlich Tumor; Female; Male; Mice; Neoplasm Transplantation; Thioct | 1980 |
Alpha-lipoic acid supplementation prevents symptoms of vitamin E deficiency.
Topics: Animals; Body Weight; Diet; Kidney; Liver; Mice; Mice, Hairless; Myocardium; Skin; Thioctic Acid; Ti | 1994 |
The antioxidant alpha-lipoic acid enhances insulin-stimulated glucose metabolism in insulin-resistant rat skeletal muscle.
Topics: Animals; Antioxidants; Biological Transport; Body Weight; Female; Glucose; Glycogen; Insulin; Insuli | 1996 |
Influence of selegiline and lipoic acid on the life expectancy of immunosuppressed mice.
Topics: Animals; Body Weight; Free Radical Scavengers; Immune Tolerance; Longevity; Mice; Mice, Nude; Monoam | 1997 |
Effects of alpha-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; gamma-L | 1998 |
Effects of diabetes and treatment with the antioxidant alpha-lipoic acid on endothelial and neurogenic responses of corpus cavernosum in rats.
Topics: Acetylcholine; Animals; Antioxidants; Atropine; Blood Glucose; Body Weight; Diabetes Mellitus, Exper | 1999 |
Involvement of lipoic acid in plasma metabolites, hepatic oxygen consumption, and metabolic response to a beta-agonist in broiler chickens.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Blood Glucose; Body Composition; Body Weigh | 1999 |
Early changes in lipid peroxidation and antioxidative defense in diabetic rat retina: effect of DL-alpha-lipoic acid.
Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glutathio | 2000 |
Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Energy Metabolism; Enz | 2000 |
The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Brain; Central Nervous System; Diabetes Mellitus, Experimental; | 2001 |
The antioxidant effect of DL-alpha-lipoic acid on copper-induced acute hepatitis in Long-Evans Cinnamon (LEC) rats.
Topics: Acute Disease; Administration, Oral; Animals; Antioxidants; Body Weight; Copper; Cytosol; Eating; En | 2001 |
Efficacy of antioxidant therapies in transient focal ischemia in mice.
Topics: Administration, Oral; Animals; Antioxidants; Body Weight; Brain; Cerebral Hemorrhage; Cerebrovascula | 2001 |
Interactions of exercise training and lipoic acid on skeletal muscle glucose transport in obese Zucker rats.
Topics: Animals; Antioxidants; Body Weight; Enzymes; Female; Glucose Tolerance Test; Glucose Transporter Typ | 2001 |
Effects of alpha-lipoic acid on deoxycorticosterone acetate-salt-induced hypertension in rats.
Topics: Animals; Aorta; Blood Pressure; Body Weight; Desoxycorticosterone; Dose-Response Relationship, Drug; | 2001 |
Lipoic acid improves survival in transgenic mouse models of Huntington's disease.
Topics: Animals; Antioxidants; Benzenesulfonates; Body Weight; Brain; Disease Models, Animal; Food, Formulat | 2001 |
Effects of exercise training and antioxidant R-ALA on glucose transport in insulin-sensitive rat skeletal muscle.
Topics: Animals; Antimetabolites; Antioxidants; Blood Glucose; Body Weight; Deoxyglucose; Female; Glucose; G | 2002 |
Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid.
Topics: Animals; Aorta; Blood Glucose; Blood Pressure; Body Weight; Glucose; Glutathione Peroxidase; Hyperte | 2002 |
Elimination of *O(2)(-)/H(2)O(2) by alpha-lipoic acid mediates the recovery of basal EDRF/NO availability and the reversal of superoxide dismutase-induced relaxation in diabetic rat aorta.
Topics: Amitrole; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experim | 2002 |
Effect of alpha-lipoic acid on the peripheral conversion of thyroxine to triiodothyronine and on serum lipid-, protein- and glucose levels.
Topics: Animals; Behavior, Animal; Blood Glucose; Blood Proteins; Body Weight; Lipids; Male; Rats; Rats, Inb | 1991 |
[Acute, subacute and chronic toxicities of thioctic acid in rats].
Topics: Administration, Oral; Alkaline Phosphatase; Animals; Bilirubin; Blood Cell Count; Blood Glucose; Blo | 1972 |
[Case of Crohn's disease in a 15-year-old girl].
Topics: Adolescent; Body Weight; Crohn Disease; Dietary Proteins; Female; Humans; Rectal Fistula; Thioctic A | 1972 |