thioctic acid has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 4 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a model of early-stage Parkinson's disease induced by a single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to Wistar rats, a neuroprotective effect of a new derivative of carnosine and α-lipoic acid (C/LA nanomicellar complex) was demonstrated." | 1.48 | Neuroprotective effect of the carnosine - α-lipoic acid nanomicellar complex in a model of early-stage Parkinson's disease. ( Berezhnoy, DS; Fedorova, TN; Kulikova, OI; Lopachev, AV; Orlova, VS; Stvolinsky, SL, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kulikova, OI | 1 |
| Berezhnoy, DS | 1 |
| Stvolinsky, SL | 1 |
| Lopachev, AV | 1 |
| Orlova, VS | 1 |
| Fedorova, TN | 1 |
| Jalali-Nadoushan, M | 1 |
| Roghani, M | 1 |
| Li, YH | 1 |
| He, Q | 1 |
| Yu, JZ | 1 |
| Liu, CY | 1 |
| Feng, L | 1 |
| Chai, Z | 1 |
| Wang, Q | 1 |
| Zhang, HZ | 1 |
| Zhang, GX | 1 |
| Xiao, BG | 1 |
| Ma, CG | 1 |
| Karunakaran, S | 1 |
| Diwakar, L | 1 |
| Saeed, U | 1 |
| Agarwal, V | 1 |
| Ramakrishnan, S | 1 |
| Iyengar, S | 1 |
| Ravindranath, V | 1 |
4 other studies available for thioctic acid and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
Neuroprotective effect of the carnosine - α-lipoic acid nanomicellar complex in a model of early-stage Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Brain; Carnosine; Dopamine; Homovanillic Acid | 2018 |
Alpha-lipoic acid protects against 6-hydroxydopamine-induced neurotoxicity in a rat model of hemi-parkinsonism.
Topics: Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Dose-Response Relationship, Drug; F | 2013 |
Lipoic acid protects dopaminergic neurons in LPS-induced Parkinson's disease model.
Topics: Animals; Antioxidants; Dopaminergic Neurons; Female; Lipopolysaccharides; Mice; Mice, Inbred C57BL; | 2015 |
Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcysteine; Alkynes; Animals; Antioxidants; Antipa | 2007 |