thioctic acid has been researched along with Autoimmune Disease in 21 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Primary biliary cirrhosis is an enigmatic autoimmune disease of women characterized by antimitochondrial antibodies and destruction of intrahepatic bile ducts." | 2.41 | Antimitochondrial antibodies in primary biliary cirrhosis: the role of xenobiotics. ( Gershwin, ME; Long, SA; Van de Water, J, 2002) |
| "Primary biliary cirrhosis (PBC) is associated with a high incidence of autoantibodies directed at mitochondrial autoantigens (the antimito-chondrial antibodies), identified as the E2 components of PDC, OGDC, and BCOADC, together with protein X and the E1 alpha and E1 beta subunits of PDC." | 2.40 | Biochemistry and autoimmune response to the 2-oxoacid dehydrogenase complexes in primary biliary cirrhosis. ( Bassendine, MF; Jones, DE; Yeaman, SJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 5 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Capece, U | 1 |
| Moffa, S | 2 |
| Improta, I | 2 |
| Di Giuseppe, G | 1 |
| Nista, EC | 1 |
| Cefalo, CMA | 1 |
| Cinti, F | 1 |
| Pontecorvi, A | 1 |
| Gasbarrini, A | 1 |
| Giaccari, A | 2 |
| Mezza, T | 2 |
| Comhaire, F | 1 |
| Deslypere, JP | 1 |
| Lu, Y | 1 |
| Li, W | 1 |
| Li, Y | 1 |
| Lian, X | 1 |
| Gullo, D | 2 |
| Magliozzo, M | 1 |
| Strano, A | 1 |
| Piazza, VG | 1 |
| Stabile, G | 1 |
| Belfiore, A | 1 |
| Li, Z | 1 |
| Su, Y | 1 |
| Yi, D | 1 |
| Wu, C | 1 |
| Fang, W | 1 |
| Wang, C | 1 |
| Rocchetti, S | 1 |
| Liu, W | 1 |
| Shi, LJ | 1 |
| Li, SG | 1 |
| Evans, JL | 1 |
| Sortino, G | 1 |
| Goldfine, ID | 1 |
| Vigneri, R | 1 |
| Michalopoulou Alevras, T | 1 |
| Guerrero Gual, M | 1 |
| Villabona Artero, C | 1 |
| Pérez-Maraver, M | 1 |
| Uchigata, Y | 2 |
| Hirata, Y | 1 |
| Iwamoto, Y | 1 |
| Bresciani, E | 1 |
| Bussi, A | 1 |
| Bazzigaluppi, E | 1 |
| Balestrieri, G | 1 |
| Long, SA | 1 |
| Van de Water, J | 1 |
| Gershwin, ME | 3 |
| Padgett, KA | 1 |
| Selmi, C | 1 |
| Kenny, TP | 1 |
| Leung, PS | 2 |
| Balkwill, DL | 1 |
| Ansari, AA | 1 |
| Coppel, RL | 2 |
| Furukawa, N | 1 |
| Miyamura, N | 1 |
| Nishida, K | 1 |
| Motoshima, H | 1 |
| Taketa, K | 1 |
| Araki, E | 1 |
| Takeuchi, Y | 1 |
| Miyamoto, T | 1 |
| Kakizawa, T | 1 |
| Shigematsu, S | 1 |
| Hashizume, K | 1 |
| Ishida, Y | 1 |
| Ohara, T | 1 |
| Okuno, Y | 1 |
| Ito, T | 1 |
| Hirota, Y | 1 |
| Furukawa, K | 1 |
| Sakaguchi, K | 1 |
| Ogawa, W | 1 |
| Kasuga, M | 1 |
| Yamada, T | 1 |
| Imai, J | 1 |
| Ishigaki, Y | 1 |
| Hinokio, Y | 1 |
| Oka, Y | 1 |
| Katagiri, H | 1 |
| Christen, U | 1 |
| Quinn, J | 1 |
| Yeaman, SJ | 2 |
| Kenna, JG | 1 |
| Clarke, JB | 1 |
| Gandolfi, AJ | 1 |
| Gut, J | 1 |
| Bassendine, MF | 1 |
| Jones, DE | 1 |
| Ansari, A | 1 |
| Munoz, S | 1 |
6 reviews available for thioctic acid and Autoimmune Disease
| Article | Year |
|---|---|
Alpha-Lipoic Acid and Glucose Metabolism: A Comprehensive Update on Biochemical and Therapeutic Features.
Topics: Antioxidants; Autoimmune Diseases; Diabetic Neuropathies; Female; Glucose; Humans; Insulin Resistanc | 2022 |
[Clinical Characteristics of Lipoic Acid-mediated Insulin Autoimmune Syndrome in Two Patients with Type 2 Diabetes Mellitus].
Topics: Autoimmune Diseases; Diabetes Mellitus, Type 2; Humans; Thioctic Acid | 2020 |
The Immunomodulatory Effect of Alpha-Lipoic Acid in Autoimmune Diseases.
Topics: Animals; Antioxidants; Autoimmune Diseases; Humans; Immunologic Factors; Thioctic Acid | 2019 |
Antimitochondrial antibodies in primary biliary cirrhosis: the role of xenobiotics.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Bile Ducts, Intrahepatic; Female; Humans; Inflammation | 2002 |
Biochemistry and autoimmune response to the 2-oxoacid dehydrogenase complexes in primary biliary cirrhosis.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Antigen-Antibody Reactions; Autoantibodies; Autoa | 1997 |
Antimitochondrial antibodies in primary biliary cirrhosis.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Autoantibodies; Autoantigens; Autoimmune Diseases | 1997 |
1 trial available for thioctic acid and Autoimmune Disease
| Article | Year |
|---|---|
News and views in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): The role of co-morbidity and novel treatments.
Topics: Adult; Animals; Antiviral Agents; Autoimmune Diseases; Comorbidity; Dichloroacetic Acid; Dietary Sup | 2020 |
14 other studies available for thioctic acid and Autoimmune Disease
| Article | Year |
|---|---|
Insulin autoimmune syndrome misdiagnosed as an insulinoma in a woman presenting with a pancreatic cystic lesion and taking alpha lipoic acid: a lesson to be learned.
Topics: Autoimmune Diseases; Diagnostic Errors; Female; Humans; Hyperinsulinism; Insulinoma; Insulins; Pancr | 2021 |
Analysis of the clinical characteristics of insulin autoimmune syndrome induced by alpha-lipoic acid.
Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Autoimmune Diseases; Blood Glucose; C-Peptide; Femal | 2021 |
Potential cause-effect relationship between insulin autoimmune syndrome and alpha lipoic acid: Two case reports.
Topics: Aged; Aged, 80 and over; Antioxidants; Autoimmune Diseases; Dietary Supplements; Female; Glucocortic | 2019 |
Insulin autoimmune syndrome (Hirata Disease) in European Caucasians taking α-lipoic acid.
Topics: Aged; Autoimmune Diseases; Europe; Female; Glucose; HLA-DRB1 Chains; Humans; Male; Middle Aged; Pred | 2014 |
[Autoimmune hypoglycemia syndrome associated with α lipoic acid consumption].
Topics: Alopecia; Antioxidants; Autoimmune Diseases; Cystine; Diagnosis, Differential; Dietary Supplements; | 2015 |
Drug-induced insulin autoimmune syndrome.
Topics: Autoimmune Diseases; Dietary Supplements; Humans; Hypoglycemia; Insulin; Methimazole; Thioctic Acid | 2009 |
Insulin autoimmune syndrome induced by α-lipoic acid in a Caucasian woman: case report.
Topics: Aged; Autoimmune Diseases; Female; Humans; Thioctic Acid | 2011 |
Phylogenetic and immunological definition of four lipoylated proteins from Novosphingobium aromaticivorans, implications for primary biliary cirrhosis.
Topics: Acyltransferases; Amino Acid Sequence; Animals; Antigens, Bacterial; Autoantigens; Autoimmune Diseas | 2005 |
Possible relevance of alpha lipoic acid contained in a health supplement in a case of insulin autoimmune syndrome.
Topics: Adult; Autoimmune Diseases; Blood Glucose; Dietary Supplements; Female; HLA-DR Antigens; HLA-DRB1 Ch | 2007 |
Insulin Autoimmune Syndrome possibly caused by alpha lipoic acid.
Topics: Autoantibodies; Autoimmune Diseases; Blood Glucose; Genotype; HLA-DR Antigens; HLA-DRB1 Chains; Huma | 2007 |
Alpha-lipoic acid and insulin autoimmune syndrome.
Topics: Adult; Antioxidants; Autoantibodies; Autoimmune Diseases; Female; Genetic Predisposition to Disease; | 2007 |
The novel agent, alpha lipoic acid, can cause the development of insulin autoimmune syndrome.
Topics: Antioxidants; Autoantibodies; Autoimmune Diseases; Humans; Hypoglycemia; Insulin; Thioctic Acid | 2007 |
Possible relevance of HLA-DRB1*0403 haplotype in insulin autoimmune syndrome induced by alpha-lipoic acid, used as a dietary supplement.
Topics: Autoimmune Diseases; Dietary Supplements; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Insulin; Thiocti | 2007 |
Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid.
Topics: Acetyltransferases; Amino Acid Sequence; Autoantigens; Autoimmune Diseases; Binding, Competitive; Ch | 1994 |