thioctic acid has been researched along with Autoimmune Disease in 21 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Excerpt | Relevance | Reference |
---|---|---|
"Primary biliary cirrhosis is an enigmatic autoimmune disease of women characterized by antimitochondrial antibodies and destruction of intrahepatic bile ducts." | 2.41 | Antimitochondrial antibodies in primary biliary cirrhosis: the role of xenobiotics. ( Gershwin, ME; Long, SA; Van de Water, J, 2002) |
"Primary biliary cirrhosis (PBC) is associated with a high incidence of autoantibodies directed at mitochondrial autoantigens (the antimito-chondrial antibodies), identified as the E2 components of PDC, OGDC, and BCOADC, together with protein X and the E1 alpha and E1 beta subunits of PDC." | 2.40 | Biochemistry and autoimmune response to the 2-oxoacid dehydrogenase complexes in primary biliary cirrhosis. ( Bassendine, MF; Jones, DE; Yeaman, SJ, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (14.29) | 18.2507 |
2000's | 8 (38.10) | 29.6817 |
2010's | 5 (23.81) | 24.3611 |
2020's | 5 (23.81) | 2.80 |
Authors | Studies |
---|---|
Capece, U | 1 |
Moffa, S | 2 |
Improta, I | 2 |
Di Giuseppe, G | 1 |
Nista, EC | 1 |
Cefalo, CMA | 1 |
Cinti, F | 1 |
Pontecorvi, A | 1 |
Gasbarrini, A | 1 |
Giaccari, A | 2 |
Mezza, T | 2 |
Comhaire, F | 1 |
Deslypere, JP | 1 |
Lu, Y | 1 |
Li, W | 1 |
Li, Y | 1 |
Lian, X | 1 |
Gullo, D | 2 |
Magliozzo, M | 1 |
Strano, A | 1 |
Piazza, VG | 1 |
Stabile, G | 1 |
Belfiore, A | 1 |
Li, Z | 1 |
Su, Y | 1 |
Yi, D | 1 |
Wu, C | 1 |
Fang, W | 1 |
Wang, C | 1 |
Rocchetti, S | 1 |
Liu, W | 1 |
Shi, LJ | 1 |
Li, SG | 1 |
Evans, JL | 1 |
Sortino, G | 1 |
Goldfine, ID | 1 |
Vigneri, R | 1 |
Michalopoulou Alevras, T | 1 |
Guerrero Gual, M | 1 |
Villabona Artero, C | 1 |
Pérez-Maraver, M | 1 |
Uchigata, Y | 2 |
Hirata, Y | 1 |
Iwamoto, Y | 1 |
Bresciani, E | 1 |
Bussi, A | 1 |
Bazzigaluppi, E | 1 |
Balestrieri, G | 1 |
Long, SA | 1 |
Van de Water, J | 1 |
Gershwin, ME | 3 |
Padgett, KA | 1 |
Selmi, C | 1 |
Kenny, TP | 1 |
Leung, PS | 2 |
Balkwill, DL | 1 |
Ansari, AA | 1 |
Coppel, RL | 2 |
Furukawa, N | 1 |
Miyamura, N | 1 |
Nishida, K | 1 |
Motoshima, H | 1 |
Taketa, K | 1 |
Araki, E | 1 |
Takeuchi, Y | 1 |
Miyamoto, T | 1 |
Kakizawa, T | 1 |
Shigematsu, S | 1 |
Hashizume, K | 1 |
Ishida, Y | 1 |
Ohara, T | 1 |
Okuno, Y | 1 |
Ito, T | 1 |
Hirota, Y | 1 |
Furukawa, K | 1 |
Sakaguchi, K | 1 |
Ogawa, W | 1 |
Kasuga, M | 1 |
Yamada, T | 1 |
Imai, J | 1 |
Ishigaki, Y | 1 |
Hinokio, Y | 1 |
Oka, Y | 1 |
Katagiri, H | 1 |
Christen, U | 1 |
Quinn, J | 1 |
Yeaman, SJ | 2 |
Kenna, JG | 1 |
Clarke, JB | 1 |
Gandolfi, AJ | 1 |
Gut, J | 1 |
Bassendine, MF | 1 |
Jones, DE | 1 |
Ansari, A | 1 |
Munoz, S | 1 |
6 reviews available for thioctic acid and Autoimmune Disease
Article | Year |
---|---|
Alpha-Lipoic Acid and Glucose Metabolism: A Comprehensive Update on Biochemical and Therapeutic Features.
Topics: Antioxidants; Autoimmune Diseases; Diabetic Neuropathies; Female; Glucose; Humans; Insulin Resistanc | 2022 |
[Clinical Characteristics of Lipoic Acid-mediated Insulin Autoimmune Syndrome in Two Patients with Type 2 Diabetes Mellitus].
Topics: Autoimmune Diseases; Diabetes Mellitus, Type 2; Humans; Thioctic Acid | 2020 |
The Immunomodulatory Effect of Alpha-Lipoic Acid in Autoimmune Diseases.
Topics: Animals; Antioxidants; Autoimmune Diseases; Humans; Immunologic Factors; Thioctic Acid | 2019 |
Antimitochondrial antibodies in primary biliary cirrhosis: the role of xenobiotics.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Bile Ducts, Intrahepatic; Female; Humans; Inflammation | 2002 |
Biochemistry and autoimmune response to the 2-oxoacid dehydrogenase complexes in primary biliary cirrhosis.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Antigen-Antibody Reactions; Autoantibodies; Autoa | 1997 |
Antimitochondrial antibodies in primary biliary cirrhosis.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Autoantibodies; Autoantigens; Autoimmune Diseases | 1997 |
1 trial available for thioctic acid and Autoimmune Disease
Article | Year |
---|---|
News and views in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): The role of co-morbidity and novel treatments.
Topics: Adult; Animals; Antiviral Agents; Autoimmune Diseases; Comorbidity; Dichloroacetic Acid; Dietary Sup | 2020 |
14 other studies available for thioctic acid and Autoimmune Disease
Article | Year |
---|---|
Insulin autoimmune syndrome misdiagnosed as an insulinoma in a woman presenting with a pancreatic cystic lesion and taking alpha lipoic acid: a lesson to be learned.
Topics: Autoimmune Diseases; Diagnostic Errors; Female; Humans; Hyperinsulinism; Insulinoma; Insulins; Pancr | 2021 |
Analysis of the clinical characteristics of insulin autoimmune syndrome induced by alpha-lipoic acid.
Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Autoimmune Diseases; Blood Glucose; C-Peptide; Femal | 2021 |
Potential cause-effect relationship between insulin autoimmune syndrome and alpha lipoic acid: Two case reports.
Topics: Aged; Aged, 80 and over; Antioxidants; Autoimmune Diseases; Dietary Supplements; Female; Glucocortic | 2019 |
Insulin autoimmune syndrome (Hirata Disease) in European Caucasians taking α-lipoic acid.
Topics: Aged; Autoimmune Diseases; Europe; Female; Glucose; HLA-DRB1 Chains; Humans; Male; Middle Aged; Pred | 2014 |
[Autoimmune hypoglycemia syndrome associated with α lipoic acid consumption].
Topics: Alopecia; Antioxidants; Autoimmune Diseases; Cystine; Diagnosis, Differential; Dietary Supplements; | 2015 |
Drug-induced insulin autoimmune syndrome.
Topics: Autoimmune Diseases; Dietary Supplements; Humans; Hypoglycemia; Insulin; Methimazole; Thioctic Acid | 2009 |
Insulin autoimmune syndrome induced by α-lipoic acid in a Caucasian woman: case report.
Topics: Aged; Autoimmune Diseases; Female; Humans; Thioctic Acid | 2011 |
Phylogenetic and immunological definition of four lipoylated proteins from Novosphingobium aromaticivorans, implications for primary biliary cirrhosis.
Topics: Acyltransferases; Amino Acid Sequence; Animals; Antigens, Bacterial; Autoantigens; Autoimmune Diseas | 2005 |
Possible relevance of alpha lipoic acid contained in a health supplement in a case of insulin autoimmune syndrome.
Topics: Adult; Autoimmune Diseases; Blood Glucose; Dietary Supplements; Female; HLA-DR Antigens; HLA-DRB1 Ch | 2007 |
Insulin Autoimmune Syndrome possibly caused by alpha lipoic acid.
Topics: Autoantibodies; Autoimmune Diseases; Blood Glucose; Genotype; HLA-DR Antigens; HLA-DRB1 Chains; Huma | 2007 |
Alpha-lipoic acid and insulin autoimmune syndrome.
Topics: Adult; Antioxidants; Autoantibodies; Autoimmune Diseases; Female; Genetic Predisposition to Disease; | 2007 |
The novel agent, alpha lipoic acid, can cause the development of insulin autoimmune syndrome.
Topics: Antioxidants; Autoantibodies; Autoimmune Diseases; Humans; Hypoglycemia; Insulin; Thioctic Acid | 2007 |
Possible relevance of HLA-DRB1*0403 haplotype in insulin autoimmune syndrome induced by alpha-lipoic acid, used as a dietary supplement.
Topics: Autoimmune Diseases; Dietary Supplements; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Insulin; Thiocti | 2007 |
Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid.
Topics: Acetyltransferases; Amino Acid Sequence; Autoantigens; Autoimmune Diseases; Binding, Competitive; Ch | 1994 |