thioctic acid has been researched along with Atherosclerosis in 17 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niacin has been widely used as an antihyperlipidemic drug, but the flushing effect restricted its clinical application." | 7.96 | Discovery of a novel niacin-lipoic acid dimer N2L attenuating atherosclerosis and dyslipidemia with non-flushing effects. ( Cai, W; Chen, J; Jiang, Y; Jin, M; Liu, P; Pi, R; Yan, J; Yao, M, 2020) |
| "Niacin has been widely used as an antihyperlipidemic drug, but the flushing effect restricted its clinical application." | 3.96 | Discovery of a novel niacin-lipoic acid dimer N2L attenuating atherosclerosis and dyslipidemia with non-flushing effects. ( Cai, W; Chen, J; Jiang, Y; Jin, M; Liu, P; Pi, R; Yan, J; Yao, M, 2020) |
| "ALA could provide a potential treatment for atherosclerosis in postmenopausal patients." | 1.48 | Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice. ( Liu, P; Shen, D; Shen, T; Sun, H; Tian, L, 2018) |
| "Atherosclerosis is a major manifestation of the pathophysiology underlying cardiovascular disease." | 1.38 | Flaxseed oil and α-lipoic acid combination reduces atherosclerosis risk factors in rats fed a high-fat diet. ( Deng, Q; Huang, F; Huang, Q; Xu, J; Yang, J; Yang, W, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, Y | 1 |
| Jin, M | 1 |
| Chen, J | 1 |
| Yan, J | 1 |
| Liu, P | 2 |
| Yao, M | 1 |
| Cai, W | 1 |
| Pi, R | 1 |
| Uchendu, C | 1 |
| Ambali, SF | 1 |
| Ayo, JO | 1 |
| Esievo, KAN | 1 |
| Shen, D | 1 |
| Tian, L | 1 |
| Shen, T | 1 |
| Sun, H | 1 |
| Xiong, S | 1 |
| Patrushev, N | 1 |
| Forouzandeh, F | 1 |
| Hilenski, L | 1 |
| Alexander, RW | 1 |
| Ying, Z | 2 |
| Chen, M | 1 |
| Xie, X | 1 |
| Wang, X | 1 |
| Kherada, N | 2 |
| Desikan, R | 2 |
| Mihai, G | 1 |
| Burns, P | 1 |
| Sun, Q | 2 |
| Rajagopalan, S | 2 |
| Zulkhairi, A | 1 |
| Zaiton, Z | 1 |
| Jamaluddin, M | 1 |
| Sharida, F | 1 |
| Mohd, TH | 1 |
| Hasnah, B | 1 |
| Nazmi, HM | 1 |
| Khairul, O | 1 |
| Zanariyah, A | 1 |
| Fedin, AI | 2 |
| Kuznetsov, MR | 2 |
| Kholopova, EA | 2 |
| Dubrovin, EE | 2 |
| Ibragimov, TM | 2 |
| Farrar, B | 1 |
| Kampfrath, T | 1 |
| Chung, Y | 1 |
| Simonetti, O | 1 |
| Deiuliis, J | 1 |
| Khan, B | 1 |
| Villamena, F | 1 |
| Parthasarathy, S | 1 |
| Beresten', NF | 1 |
| Kuznetsova, VF | 1 |
| Tugdumov, BV | 1 |
| Lee, WR | 1 |
| Kim, A | 1 |
| Kim, KS | 1 |
| Park, YY | 1 |
| Park, JH | 1 |
| Kim, KH | 1 |
| Kim, SJ | 1 |
| Park, KK | 1 |
| Harding, SV | 1 |
| Rideout, TC | 1 |
| Jones, PJ | 1 |
| Xu, J | 1 |
| Yang, W | 1 |
| Deng, Q | 1 |
| Huang, Q | 1 |
| Yang, J | 1 |
| Huang, F | 1 |
| Lee, WJ | 1 |
| Lee, IK | 1 |
| Kim, HS | 1 |
| Kim, YM | 1 |
| Koh, EH | 1 |
| Won, JC | 1 |
| Han, SM | 1 |
| Kim, MS | 1 |
| Jo, I | 1 |
| Oh, GT | 1 |
| Park, IS | 1 |
| Youn, JH | 1 |
| Park, SW | 1 |
| Lee, KU | 1 |
| Park, JY | 1 |
| Kumar, SA | 2 |
| Sudhahar, V | 2 |
| Varalakshmi, P | 2 |
| Yi, X | 1 |
| Maeda, N | 1 |
| Zhang, WJ | 1 |
| Bird, KE | 1 |
| McMillen, TS | 1 |
| LeBoeuf, RC | 1 |
| Hagen, TM | 1 |
| Frei, B | 1 |
2 reviews available for thioctic acid and Atherosclerosis
| Article | Year |
|---|---|
[Present-day possibilities of correcting impaired autoregulation of the cerebral circulation].
Topics: Antioxidants; Atherosclerosis; Cerebrovascular Circulation; Homeostasis; Humans; Lipid Peroxidation; | 2009 |
Evidence for using alpha-lipoic acid in reducing lipoprotein and inflammatory related atherosclerotic risk.
Topics: Antioxidants; Atherosclerosis; Cholesterol, HDL; Cholesterol, LDL; Dietary Supplements; Inflammation | 2012 |
15 other studies available for thioctic acid and Atherosclerosis
| Article | Year |
|---|---|
Discovery of a novel niacin-lipoic acid dimer N2L attenuating atherosclerosis and dyslipidemia with non-flushing effects.
Topics: Animals; Atherosclerosis; Cell Line; Cricetulus; Dimerization; Disease Models, Animal; Drug Design; | 2020 |
Chronic co-exposure to chlorpyrifos and deltamethrin pesticides induces alterations in serum lipids and oxidative stress in Wistar rats: mitigating role of alpha-lipoic acid.
Topics: Animals; Antioxidants; Atherosclerosis; Chlorpyrifos; Cholesterol, LDL; Lipids; Male; Malondialdehyd | 2018 |
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Topics: Animals; Aorta; Atherosclerosis; Disease Models, Animal; Endothelial Cells; Female; Humans; Hydrogen | 2018 |
PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases.
Topics: Animals; Antioxidant Response Elements; Atherosclerosis; Blood Vessels; DNA Damage; Mice; Mice, Inbr | 2015 |
Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling.
Topics: Animals; Atherosclerosis; Blood Vessels; Chemotaxis, Leukocyte; Disease Models, Animal; Disease Prog | 2016 |
Alpha lipoic acid possess dual antioxidant and lipid lowering properties in atherosclerotic-induced New Zealand White rabbit.
Topics: Animals; Antioxidants; Aorta; Atherosclerosis; Cholesterol; Hypolipidemic Agents; Lipid Peroxidation | 2008 |
Lipoic acid effects on established atherosclerosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Atherosclerosis; Blood Glucose; B | 2010 |
[Correction of disordered cerebral blood flow autoregulation in atherosclerosis].
Topics: Adult; Aged; Atherosclerosis; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Homeost | 2009 |
Alpha-lipoic acid attenuates atherosclerotic lesions and inhibits proliferation of vascular smooth muscle cells through targeting of the Ras/MEK/ERK signaling pathway.
Topics: Animals; Aorta, Thoracic; Atherosclerosis; Cell Adhesion Molecules; Cell Proliferation; Cells, Cultu | 2012 |
Flaxseed oil and α-lipoic acid combination reduces atherosclerosis risk factors in rats fed a high-fat diet.
Topics: Animals; Atherosclerosis; C-Reactive Protein; Catalase; Diet, High-Fat; Dietary Supplements; Glutath | 2012 |
Alpha-lipoic acid prevents endothelial dysfunction in obese rats via activation of AMP-activated protein kinase.
Topics: Adenoviridae; AMP-Activated Protein Kinase Kinases; Animals; Aorta; Apoptosis; Atherosclerosis; Cell | 2005 |
Protective role of eicosapentaenoate-lipoate (EPA-LA) derivative in combating oxidative hepatocellular injury in hypercholesterolemic atherogenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Atherosclerosis; Cholesterol; Deoxyguanosine; Disease Models, | 2006 |
Oxidative renal injury and lipoprotein oxidation in hypercholesterolemic atherogenesis: Role of eicosapentaenoate-lipoate (EPA-LA) derivative.
Topics: Animals; Atherosclerosis; Diet, Atherogenic; Dietary Supplements; Eicosapentaenoic Acid; Hypercholes | 2006 |
alpha-Lipoic acid prevents the increase in atherosclerosis induced by diabetes in apolipoprotein E-deficient mice fed high-fat/low-cholesterol diet.
Topics: Animals; Antioxidants; Apolipoproteins E; Aryldialkylphosphatase; Atherosclerosis; Biomarkers; Blood | 2006 |
Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Body Weight; Cholesterol; Dietary Supplements; Disease | 2008 |