thioctic acid has been researched along with Arteriosclerosis in 14 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "N(epsilon)-(Carboxymethyl)lysine (CML), a major product of oxidative modification of glycated proteins, has been suggested to represent a general marker of oxidative stress and long-term damage to proteins in aging, atherosclerosis, and diabetes." | 7.69 | Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. ( Nerlich, AG; Schleicher, ED; Wagner, E, 1997) |
| "Many clinical and epidemiological studies show that mild hyperhomocysteinemia is associated with premature vascular disease." | 3.73 | Elimination of high amounts of extracellular homocysteine in human cell lines. ( Hultberg, B, 2005) |
| "N(epsilon)-(Carboxymethyl)lysine (CML), a major product of oxidative modification of glycated proteins, has been suggested to represent a general marker of oxidative stress and long-term damage to proteins in aging, atherosclerosis, and diabetes." | 3.69 | Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. ( Nerlich, AG; Schleicher, ED; Wagner, E, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bassi, E | 1 |
| Liberman, M | 1 |
| Martinatti, MK | 1 |
| Bortolotto, LA | 1 |
| Laurindo, FR | 1 |
| HAKAMADA, H | 1 |
| OTSUKA, K | 1 |
| TAKESHITA, T | 1 |
| ANAMI, O | 1 |
| Wollin, SD | 1 |
| Jones, PJ | 1 |
| Block, G | 1 |
| Jensen, C | 1 |
| Dietrich, M | 1 |
| Norkus, EP | 1 |
| Hudes, M | 1 |
| Packer, L | 1 |
| Hultberg, B | 1 |
| Shih, JC | 1 |
| Chen, C | 1 |
| Loo, G | 1 |
| Schleicher, ED | 1 |
| Wagner, E | 1 |
| Nerlich, AG | 1 |
| Viita, H | 1 |
| Sen, CK | 1 |
| Roy, S | 1 |
| Siljamäki, T | 1 |
| Nikkari, T | 1 |
| Ylä-Herttuala, S | 1 |
| Parcell, S | 1 |
| Kirk, JE | 2 |
| Ivanov, VN | 1 |
| Ivkov, VG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Obesity, Inflammation and Oxidative Stress[NCT01028976] | Phase 3 | 512 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thioctic acid and Arteriosclerosis
| Article | Year |
|---|---|
Alpha-lipoic acid and cardiovascular disease.
Topics: Antioxidants; Arteriosclerosis; Cardiovascular Diseases; Free Radical Scavengers; Humans; Lipids; Ri | 2003 |
Sulfur in human nutrition and applications in medicine.
Topics: Amino Acids, Essential; Antioxidants; Arteriosclerosis; Chondroitin Sulfates; Diet; Dimethyl Sulfoxi | 2002 |
1 trial available for thioctic acid and Arteriosclerosis
| Article | Year |
|---|---|
Plasma C-reactive protein concentrations in active and passive smokers: influence of antioxidant supplementation.
Topics: alpha-Tocopherol; Antioxidants; Arteriosclerosis; Ascorbic Acid; Body Mass Index; C-Reactive Protein | 2004 |
11 other studies available for thioctic acid and Arteriosclerosis
| Article | Year |
|---|---|
Lipoic acid, but not tempol, preserves vascular compliance and decreases medial calcification in a model of elastocalcinosis.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Compliance; Cyclic N-Oxides; Disease Models, Animal; Mal | 2014 |
[Action of thioctic acid (Lipoicin) on metabolic abnormalities in arteriosclerosis patients].
Topics: Arteriosclerosis; Humans; Thioctic Acid | 1962 |
Elimination of high amounts of extracellular homocysteine in human cell lines.
Topics: Adenosine; Antioxidants; Arteriosclerosis; Carcinoma, Hepatocellular; Cell Line, Tumor; HeLa Cells; | 2005 |
Atherosclerosis in Japanese quail and the effect of lipoic acid.
Topics: Animals; Aorta; Arteriosclerosis; Coturnix; Delayed-Action Preparations; Diet, Atherogenic; Dietary | 1983 |
Inhibition of lecithin: cholesterol acyltransferase activity in human blood plasma by cigarette smoke extract and reactive aldehydes.
Topics: Adult; Aldehydes; Arteriosclerosis; Glutathione; Humans; Male; Nicotiana; Phosphatidylcholine-Sterol | 1995 |
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Ch | 1997 |
High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells.
Topics: Antioxidants; Arachidonate 15-Lipoxygenase; Arteriosclerosis; Cell Adhesion; Cell Line; Dose-Respons | 1999 |
Coenzyme contents of arterial tissue.
Topics: Age Factors; Animals; Aorta; Arteries; Arteriosclerosis; Carnitine; Chromatography, Paper; Coenzyme | 1974 |
Effect of lipoic acid on tissue respiration in rabbits with experimental atherosclerosis.
Topics: Analysis of Variance; Animals; Aorta; Arteriosclerosis; Blood Vessels; Cholesterol; Female; Lipoprot | 1974 |
Lipoic acid.
Topics: Adolescent; Adult; Aged; Aging; Aorta; Arteries; Arteriosclerosis; Humans; Middle Aged; Pulmonary Ar | 1974 |
[Lipoic (thioctic) acid and its significance in hepatology].
Topics: Animals; Arrhythmias, Cardiac; Arteriosclerosis; Carbohydrate Metabolism; Diabetes Mellitus; Humans; | 1969 |