Page last updated: 2024-10-19

thioctic acid and Allodynia

thioctic acid has been researched along with Allodynia in 8 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Research Excerpts

ExcerptRelevanceReference
" After 15 days, rats were investigated for the presence of mechanical and cold allodynia, and those with allodynia received intraperitoneal injection with normal saline or 1, 5, or 10 mg/kg thioctic acid."7.81The effect of thioctic acid on allodynia in a rat vincristine-induced neuropathy model. ( Chung, EY; Kahng, J; Kim, TK; Kim, YS; Moon, JY, 2015)
" The aim of this study was to evaluate the interaction of pregabalin + thioctic acid or pregabalin + α-tocopherol on allodynia and motor performance in neonatal streptozotocin-induced diabetic rats."3.88Antiallodynic interaction and motor performance of the pregabalin/thioctic acid and pregabalin/α-tocopherol combinations in neonatal streptozotocin-induced diabetic rats. ( Araiza-Saldaña, CI; Cruz-Álvarez, LE; Flores-Murrieta, FJ; Huerta-Cruz, JC; Reyes-García, JG; Rocha-González, HI; Zúñiga-Romero, Á, 2018)
" After 15 days, rats were investigated for the presence of mechanical and cold allodynia, and those with allodynia received intraperitoneal injection with normal saline or 1, 5, or 10 mg/kg thioctic acid."3.81The effect of thioctic acid on allodynia in a rat vincristine-induced neuropathy model. ( Chung, EY; Kahng, J; Kim, TK; Kim, YS; Moon, JY, 2015)
"Central neuropathic pain is a common untreated symptom in progressive multiple sclerosis (PMS) and is associated with poor quality of life and interference with patients' daily activities."1.56Nociception in a Progressive Multiple Sclerosis Model in Mice Is Dependent on Spinal TRPA1 Channel Activation. ( Antoniazzi, CT; Dalenogare, DP; de Almeida, AS; Ferreira, J; Fialho, MFP; Kudsi, SQ; Lückemeyer, DD; Oliveira, SM; Pereira, GC; Pereira, VL; Ritter, C; Trevisan, G, 2020)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
de Almeida, AS2
Rigo, FK1
De Prá, SD1
Milioli, AM1
Pereira, GC2
Lückemeyer, DD2
Antoniazzi, CT2
Kudsi, SQ2
Araújo, DMPA1
Oliveira, SM2
Ferreira, J3
Trevisan, G3
Ritter, C1
Dalenogare, DP1
Pereira, VL1
Fialho, MFP1
Joksimovic, SL1
Lamborn, N1
Jevtovic-Todorovic, V1
Todorovic, SM1
Hu, J1
Qin, X1
Song, ZY1
Yang, PP1
Feng, Y1
Sun, Q1
Xu, GY1
Zhang, HH1
Cruz-Álvarez, LE1
Zúñiga-Romero, Á1
Huerta-Cruz, JC1
Flores-Murrieta, FJ1
Reyes-García, JG1
Araiza-Saldaña, CI1
Rocha-González, HI1
Jin, HY1
Lee, KA1
Wu, JZ1
Baek, HS1
Park, TS1
Kahng, J1
Kim, TK1
Chung, EY1
Kim, YS1
Moon, JY1
Benemei, S1
Materazzi, S1
De Logu, F1
De Siena, G1
Fusi, C1
Fortes Rossato, M1
Coppi, E1
Marone, IM1
Geppetti, P1
Nassini, R1

Other Studies

8 other studies available for thioctic acid and Allodynia

ArticleYear
Role of transient receptor potential ankyrin 1 (TRPA1) on nociception caused by a murine model of breast carcinoma.
    Pharmacological research, 2020, Volume: 152

    Topics: Acetanilides; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Cancer Pain; Cell Line, Tumor;

2020
Nociception in a Progressive Multiple Sclerosis Model in Mice Is Dependent on Spinal TRPA1 Channel Activation.
    Molecular neurobiology, 2020, Volume: 57, Issue:5

    Topics: Acetanilides; Acetophenones; Analgesics; Animals; Antipyrine; Dipyrone; Encephalomyelitis, Autoimmun

2020
Alpha lipoic acid attenuates evoked and spontaneous pain following surgical skin incision in rats.
    Channels (Austin, Tex.), 2021, Volume: 15, Issue:1

    Topics: Animals; Hyperalgesia; Pain, Postoperative; Rats; Surgical Wound; Thioctic Acid

2021
Alpha-lipoic Acid suppresses P2X receptor activities and visceral hypersensitivity to colorectal distention in diabetic rats.
    Scientific reports, 2017, 06-28, Volume: 7, Issue:1

    Topics: Animals; Colon; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Fem

2017
Antiallodynic interaction and motor performance of the pregabalin/thioctic acid and pregabalin/α-tocopherol combinations in neonatal streptozotocin-induced diabetic rats.
    Drug development research, 2018, Volume: 79, Issue:7

    Topics: alpha-Tocopherol; Analgesics; Animals; Animals, Newborn; Antioxidants; Diabetes Mellitus, Experiment

2018
The neuroprotective benefit from pioglitazone (PIO) addition on the alpha lipoic acid (ALA)-based treatment in experimental diabetic rats.
    Endocrine, 2014, Volume: 47, Issue:3

    Topics: Animals; Axons; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Therapy,

2014
The effect of thioctic acid on allodynia in a rat vincristine-induced neuropathy model.
    The Journal of international medical research, 2015, Volume: 43, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Dose-Response Relationship,

2015
TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress.
    Brain : a journal of neurology, 2016, Volume: 139, Issue:Pt 5

    Topics: Acetanilides; Acetophenones; Animals; Chemokine CCL2; Clodronic Acid; Hyperalgesia; Macrophages; Mal

2016