thioctic acid has been researched along with Albuminuria in 9 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to investigate the effects of combined administration of lipoic acid and pyridoxine on albuminuria, oxidative stress, blood pressure, serum advanced glycation end-products, nitric oxide (NO), and endothelin-1 in patients with diabetic nephropathy." | 9.17 | Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy. ( Hedayati, M; Hosseinpanah, F; Nafar, M; Noori, N; Tabibi, H, 2013) |
| "This study was designed to investigate the effects of combined administration of lipoic acid and pyridoxine on albuminuria, oxidative stress, blood pressure, serum advanced glycation end-products, nitric oxide (NO), and endothelin-1 in patients with diabetic nephropathy." | 5.17 | Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy. ( Hedayati, M; Hosseinpanah, F; Nafar, M; Noori, N; Tabibi, H, 2013) |
| " Compared with control rats, D developed increased urinary excretion of albumin and transforming growth factor beta, renal insufficiency, glomerular mesangial matrix expansion, and glomerulosclerosis in association with depletion of glutathione and accumulation of malondialdehyde in renal cortex." | 3.71 | Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes. ( Craven, PA; DeRubertis, FR; Liachenko, J; Melhem, MF, 2002) |
| "Forty-nine patients (34 with Type 1 diabetes, 15 with Type 2 diabetes) had no antioxidant treatment and served as a control group." | 2.70 | Effect of alpha-lipoic acid on the progression of endothelial cell damage and albuminuria in patients with diabetes mellitus: an exploratory study. ( Amiral, J; Borcea, V; Ehret, T; Gehrke, S; Henkels, M; Hofmann, M; Isermann, B; Morcos, M; Nawroth, PP; Schiekofer, S; Tritschler, H; Wahl, P; Ziegler, R, 2001) |
| "Patients with diabetic nephropathy showed higher NF-kappaB binding activity in Electrophoretic Mobility Shift Assays and stronger immunohistological staining for activated NF-kappaBp65 than patients without renal complications." | 1.30 | Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB. ( Abdel Khalek, AK; Amiral, J; Bierhaus, A; Borcea, V; Henkels, M; Hofmann, MA; Isermann, B; Joswig, M; Kanitz, M; Morcos, M; Nawroth, PP; Ritz, E; Schiekofer, S; Treusch, A; Tritschler, H; Wahl, P; Weiss, T; Ziegler, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Noori, N | 1 |
| Tabibi, H | 1 |
| Hosseinpanah, F | 1 |
| Hedayati, M | 1 |
| Nafar, M | 1 |
| Rahman, ST | 1 |
| Merchant, N | 1 |
| Haque, T | 1 |
| Wahi, J | 1 |
| Bhaheetharan, S | 1 |
| Ferdinand, KC | 1 |
| Khan, BV | 1 |
| Obrosova, IG | 1 |
| Fathallah, L | 1 |
| Liu, E | 1 |
| Nourooz-Zadeh, J | 2 |
| Mervaala, E | 1 |
| Finckenberg, P | 1 |
| Lapatto, R | 1 |
| Müller, DN | 1 |
| Park, JK | 1 |
| Dechend, R | 1 |
| Ganten, D | 1 |
| Vapaatalo, H | 1 |
| Luft, FC | 1 |
| Bhatti, F | 1 |
| Mankhey, RW | 1 |
| Asico, L | 1 |
| Quinn, MT | 1 |
| Welch, WJ | 1 |
| Maric, C | 1 |
| Hofmann, MA | 1 |
| Schiekofer, S | 2 |
| Isermann, B | 2 |
| Kanitz, M | 1 |
| Henkels, M | 2 |
| Joswig, M | 1 |
| Treusch, A | 1 |
| Morcos, M | 2 |
| Weiss, T | 1 |
| Borcea, V | 3 |
| Abdel Khalek, AK | 1 |
| Amiral, J | 2 |
| Tritschler, H | 3 |
| Ritz, E | 1 |
| Wahl, P | 3 |
| Ziegler, R | 3 |
| Bierhaus, A | 1 |
| Nawroth, PP | 3 |
| Wolff, SP | 1 |
| Klevesath, M | 1 |
| Hofmann, M | 2 |
| Urich, H | 1 |
| Halliwell, B | 1 |
| Gehrke, S | 1 |
| Ehret, T | 1 |
| Melhem, MF | 1 |
| Craven, PA | 1 |
| Liachenko, J | 1 |
| DeRubertis, FR | 1 |
3 trials available for thioctic acid and Albuminuria
| Article | Year |
|---|---|
Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy.
Topics: Adult; Aged; Albuminuria; Arginine; Blood Pressure; Creatinine; Diabetic Nephropathies; Double-Blind | 2013 |
The impact of lipoic acid on endothelial function and proteinuria in quinapril-treated diabetic patients with stage I hypertension: results from the QUALITY study.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cross-Over Studies; Di | 2012 |
Effect of alpha-lipoic acid on the progression of endothelial cell damage and albuminuria in patients with diabetes mellitus: an exploratory study.
Topics: Albuminuria; Antioxidants; Biomarkers; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, | 2001 |
6 other studies available for thioctic acid and Albuminuria
| Article | Year |
|---|---|
Early oxidative stress in the diabetic kidney: effect of DL-alpha-lipoic acid.
Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus; F2-Isoprostanes; | 2003 |
Lipoic acid supplementation prevents angiotensin II-induced renal injury.
Topics: Albuminuria; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; C | 2003 |
Mechanisms of antioxidant and pro-oxidant effects of alpha-lipoic acid in the diabetic and nondiabetic kidney.
Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephrop | 2005 |
Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB.
Topics: Adult; Albuminuria; Antioxidants; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nep | 1999 |
alpha-Lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria.
Topics: Albuminuria; Antioxidants; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female | 1999 |
Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes.
Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephrop | 2002 |