thioctic acid has been researched along with Akinetic-Rigid Variant of Huntington Disease in 5 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A wide variety of models of Huntington's disease have been developed including yeast, Caenorhabditis elegans, Drosophila melanogaster and mouse." | 2.42 | Experimental therapeutics in Huntington's disease: are models useful for therapeutic trials? ( Bates, GP; Hockly, E, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mehrotra, A | 3 |
| Sandhir, R | 3 |
| Kanwal, A | 1 |
| Banerjee, SK | 1 |
| Sood, A | 1 |
| Bates, GP | 1 |
| Hockly, E | 1 |
| Andreassen, OA | 1 |
| Ferrante, RJ | 1 |
| Dedeoglu, A | 1 |
| Beal, MF | 1 |
1 review available for thioctic acid and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Experimental therapeutics in Huntington's disease: are models useful for therapeutic trials?
Topics: Acetamides; Animals; Antioxidants; Creatine; Disease Models, Animal; Evaluation Studies as Topic; Hu | 2003 |
4 other studies available for thioctic acid and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Mitochondrial cofactors in experimental Huntington's disease: behavioral, biochemical and histological evaluation.
Topics: Acetylcarnitine; Animals; Antioxidants; Behavior, Animal; Brain; Chromatography, Thin Layer; Disease | 2014 |
Mitochondrial modulators in experimental Huntington's disease: reversal of mitochondrial dysfunctions and cognitive deficits.
Topics: Acetylcarnitine; Animals; Cognition Disorders; Drug Therapy, Combination; Female; Huntington Disease | 2015 |
Mitochondrial modulators improve lipid composition and attenuate memory deficits in experimental model of Huntington's disease.
Topics: Acetylcarnitine; Animals; Behavior, Animal; Brain; Cholesterol; Chromatography, Thin Layer; Cognitio | 2015 |
Lipoic acid improves survival in transgenic mouse models of Huntington's disease.
Topics: Animals; Antioxidants; Benzenesulfonates; Body Weight; Brain; Disease Models, Animal; Food, Formulat | 2001 |