Page last updated: 2024-10-19

thioctic acid and Acidosis

thioctic acid has been researched along with Acidosis in 9 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.

Research Excerpts

ExcerptRelevanceReference
" This infant was found to have lactic acidosis, low cerebrospinal fluid glucose, hyperalaninemia, and increased levels of urine lactate, pyruvate and alanine."7.65Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid. ( Komiya, K; Maesaka, H; Misugi, K; Tada, K, 1976)
" This infant was found to have lactic acidosis, low cerebrospinal fluid glucose, hyperalaninemia, and increased levels of urine lactate, pyruvate and alanine."3.65Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid. ( Komiya, K; Maesaka, H; Misugi, K; Tada, K, 1976)
"It is a longstanding debate whether cancer is one disease or a set of very diverse diseases."2.55The Warburg Effect and the Hallmarks of Cancer. ( Alfarouk, KO; Schwartz, L; Supuran, CT, 2017)
" Although it is a safe oral molecule, there have been eight cases of ALA toxicity reported."1.91Alpha Lipoic Acid Toxicity: The First Reported Mortality in an Adult Patient After Multiorgan Failure. ( Abu-Alfa, A; Al Balushi, H; El Helou, C; El Zahran, T; Gittinger, M; Halabi, Z; Kaakour, A; Steck, AR, 2023)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Halabi, Z1
El Helou, C1
Al Balushi, H1
Gittinger, M1
Steck, AR1
Kaakour, A1
Abu-Alfa, A1
El Zahran, T1
Emir, DF1
Ozturan, IU1
Yilmaz, S1
Gulen, M1
Simsek, Y1
Oner, E1
Satar, S1
Schwartz, L1
Supuran, CT1
Alfarouk, KO1
Matalon, R1
Stumpf, DA1
Michals, K1
Hart, RD1
Parks, JK1
Goodman, SI1
Goodyer, PR1
Lancaster, GA1
Maesaka, H1
Komiya, K1
Misugi, K1
Tada, K1
Burlev, VA1
Mamedalieva, NM1
Sidel'nikova, VM1

Reviews

2 reviews available for thioctic acid and Acidosis

ArticleYear
The Warburg Effect and the Hallmarks of Cancer.
    Anti-cancer agents in medicinal chemistry, 2017, Volume: 17, Issue:2

    Topics: Acidosis; Adenosine Triphosphate; Alkalosis; Animals; Carbon Dioxide; Cell Proliferation; Citrates;

2017
Thiamine-responsive lactic acidosis.
    Nutrition reviews, 1974, Volume: 32, Issue:3

    Topics: Acidosis; Alanine; Biotin; Carbohydrate Metabolism, Inborn Errors; Dietary Carbohydrates; Female; Hu

1974

Other Studies

7 other studies available for thioctic acid and Acidosis

ArticleYear
Alpha Lipoic Acid Toxicity: The First Reported Mortality in an Adult Patient After Multiorgan Failure.
    The Journal of emergency medicine, 2023, Volume: 64, Issue:2

    Topics: Acidosis; Adolescent; Adult; Anticonvulsants; Antioxidants; Child; Female; Humans; Seizures; Thiocti

2023
Alpha lipoic acid intoxicatıon: An adult.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:6

    Topics: Acidosis; Antioxidants; Critical Care; Drug Overdose; Female; Humans; Suicide, Attempted; Thioctic A

2018
First description of the alpha lipoic acid intoxication in an adult patient worldwide following oral administration.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:6

    Topics: Acidosis; Administration, Oral; Adult; Antioxidants; Drug Overdose; Emergency Medical Services; Fema

2018
Lipoamide dehydrogenase deficiency with primary lactic acidosis: favorable response to treatment with oral lipoic acid.
    The Journal of pediatrics, 1984, Volume: 104, Issue:1

    Topics: Acidosis; Administration, Oral; Dihydrolipoamide Dehydrogenase; Fibroblasts; Humans; Infant; Ketoglu

1984
Inherited lactic acidosis: correction of the defect in cultured fibroblasts.
    Pediatric research, 1984, Volume: 18, Issue:11

    Topics: Acidosis; Cells, Cultured; Electron Transport; Female; Fibroblasts; Humans; Infant, Newborn; Lactate

1984
Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid.
    European journal of pediatrics, 1976, May-04, Volume: 122, Issue:2

    Topics: Acidosis; Alanine; Female; Glucose; Humans; Infant; Intellectual Disability; Lactates; Liver; Metabo

1976
[Acid-base equilibrium and blood gases in pregnant women with habitual abortion after metabolic therapy].
    Akusherstvo i ginekologiia, 1992, Issue:2

    Topics: Abortion, Habitual; Acid-Base Equilibrium; Acidosis; Adult; Carbon Dioxide; Drug Combinations; Drug

1992