Page last updated: 2024-10-19

thioctic acid and Acidosis, Lactic

thioctic acid has been researched along with Acidosis, Lactic in 5 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.

Research Excerpts

ExcerptRelevanceReference
"PDHc deficiency was demonstrated in muscle and fibroblasts without detectable PDHA1 mutations."1.36Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain. ( Briones, P; Font, A; Pineda, M; Quintana, E; Ribes, A; Tort, F; Vilaseca, MA, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tort, F2
Ferrer-Cortès, X1
Thió, M1
Navarro-Sastre, A1
Matalonga, L1
Quintana, E2
Bujan, N1
Arias, A1
García-Villoria, J1
Acquaviva, C1
Vianey-Saban, C1
Artuch, R1
García-Cazorla, À1
Briones, P2
Ribes, A2
Orsucci, D1
Filosto, M1
Siciliano, G1
Mancuso, M1
Pineda, M1
Font, A1
Vilaseca, MA1
Yoshida, I1
Sweetman, L1
Kulovich, S1
Nyhan, WL1
Robinson, BH1
Byrd, DJ1
Krohn, HP1
Winkler, L1
Steinborn, C1
Hadam, M1
Brodehl, J1
Hunneman, DH1

Reviews

1 review available for thioctic acid and Acidosis, Lactic

ArticleYear
Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction.
    Nutrition reviews, 2009, Volume: 67, Issue:8

    Topics: Acidosis, Lactic; Animals; Antioxidants; Carnitine; Creatine; Dietary Supplements; Electron Transpor

2009

Other Studies

4 other studies available for thioctic acid and Acidosis, Lactic

ArticleYear
Mutations in the lipoyltransferase LIPT1 gene cause a fatal disease associated with a specific lipoylation defect of the 2-ketoacid dehydrogenase complexes.
    Human molecular genetics, 2014, Apr-01, Volume: 23, Issue:7

    Topics: Acidosis, Lactic; Acyltransferases; Amino Acid Metabolism, Inborn Errors; Animals; Cells, Cultured;

2014
Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Acidosis, Lactic; Adult; Amino Acid Sequence; Base Sequence; Biomarkers; Blepharoptosis; Cells, Cult

2010
Effect of lipoic acid in a patient with defective activity of pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase, and branched-chain keto acid dehydrogenase.
    Pediatric research, 1990, Volume: 27, Issue:1

    Topics: 3-Hydroxybutyric Acid; 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acidosis, Lactic; Acidosis

1990
Neonatal pyruvate dehydrogenase deficiency with lipoate responsive lactic acidaemia and hyperammonaemia.
    European journal of pediatrics, 1989, Volume: 148, Issue:6

    Topics: Acidosis, Lactic; Ammonia; Female; Humans; Infant, Newborn; Pyruvate Dehydrogenase Complex Deficienc

1989