thioctic acid has been researched along with ALS - Amyotrophic Lateral Sclerosis in 4 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated the toxic effects of excess extracellular copper on motor neuronal cells expressing human mutant SOD1 (G93A), and evaluated the neuroprotective effects of energy metabolism intermediates or cofactors." | 1.33 | Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity. ( Kim, HJ; Kim, JM; Kim, M; Lee, KW; Park, JH; Sung, JJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, T | 1 |
| Cheng, J | 1 |
| Wang, S | 1 |
| Wang, X | 1 |
| Jiang, H | 1 |
| Yang, Y | 1 |
| Wang, Y | 1 |
| Zhang, C | 1 |
| Liang, W | 1 |
| Feng, H | 1 |
| Kim, HJ | 1 |
| Kim, JM | 1 |
| Park, JH | 1 |
| Sung, JJ | 1 |
| Kim, M | 1 |
| Lee, KW | 1 |
| Andreassen, OA | 1 |
| Dedeoglu, A | 1 |
| Friedlich, A | 1 |
| Ferrante, KL | 1 |
| Hughes, D | 1 |
| Szabo, C | 1 |
| Beal, MF | 1 |
| Currier, RD | 1 |
| Haerer, AF | 1 |
4 other studies available for thioctic acid and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
α-Lipoic acid attenuates oxidative stress and neurotoxicity via the ERK/Akt-dependent pathway in the mutant hSOD1 related Drosophila model and the NSC34 cell line of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Cell Line; Disease Models, An | 2018 |
Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity.
Topics: Amyotrophic Lateral Sclerosis; Cell Death; Cell Line, Tumor; Copper; Energy Metabolism; Free Radical | 2005 |
Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice.
Topics: Amphetamines; Amyotrophic Lateral Sclerosis; Animals; Female; Male; Mice; Mice, Transgenic; Motor Sk | 2001 |
Amyotrophic lateral sclerosis and metallic toxins.
Topics: Adult; Aged; Agricultural Workers' Diseases; Amyotrophic Lateral Sclerosis; Arsenic; Chelating Agent | 1968 |