thiocarlide has been researched along with Tuberculosis--Pulmonary* in 61 studies
2 review(s) available for thiocarlide and Tuberculosis--Pulmonary
Article | Year |
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Recycling and refurbishing old antitubercular drugs: the encouraging case of inhibitors of mycolic acid biosynthesis.
One of the first approaches undertaken in the quest for antitubercular compounds was that of understanding the mechanism of action of old drugs and proposing chemical modifications or other strategies to improve their activity, generally lost to the mechanisms of resistance developed by Mycobacterium tuberculosis. A leading case was the work carried out on a set of compounds with proven activity on the essential pathway of the synthesis of mycolic acids. As a result, different solutions were presented, improving the activity of those inhibitors or producing novel compounds acting on the same molecular target(s), but avoiding the most common resistance strategies developed by the tubercle bacilli. This review focuses on the activity of those compounds, developed following the completion of the studies on several of the classic antitubercular drugs. Topics: Antitubercular Agents; Drug Design; Drug Resistance, Multiple, Bacterial; Ethionamide; Humans; Isoniazid; Mycobacterium tuberculosis; Mycolic Acids; Phenylthiourea; Structure-Activity Relationship; Thioacetazone; Tuberculosis, Pulmonary | 2013 |
[Thiocarlide. Attempt of an evaluation].
Topics: Aminosalicylic Acids; Animals; Bacteria; Drug Resistance, Microbial; Ethionamide; Guinea Pigs; Humans; Isoniazid; Phenylthiourea; Rabbits; Solubility; Streptomycin; Thiosemicarbazones; Tuberculosis; Tuberculosis, Pulmonary; Tuberculosis, Renal | 1969 |
10 trial(s) available for thiocarlide and Tuberculosis--Pulmonary
Article | Year |
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[Rifampicin in the treatment of active pulmonary tuberculosis. Controlled trial of isoniazid-rifampicin-thiocarlide versus isoniazid-streptomycin-thiocarlide in untreated tuberculosis. Treatment of relapses with the combination rifampicin-ethambutol-thioc
Topics: Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol; Gastrointestinal Diseases; Humans; Isoniazid; Mycobacterium tuberculosis; Phenylthiourea; Pyridoxine; Recurrence; Rifampin; Streptomycin; Thrombocytopenia; Time Factors; Tuberculosis, Pulmonary | 1974 |
Controlled clinical trials with Isoxyl.
Topics: Clinical Trials as Topic; Cycloserine; Drug Combinations; Drug Synergism; Ethionamide; Evaluation Studies as Topic; Humans; Isoniazid; Phenylthiourea; Pyrazinamide; Tuberculosis, Pulmonary | 1970 |
Clinical data on 4-4' diisoamyloxythiocarbanilide (Isoxyl).
Topics: Adult; Clinical Trials as Topic; Drug Combinations; Drug Synergism; Female; Humans; Isoniazid; Lung; Male; Middle Aged; Phenylthiourea; Radiography; Sputum; Tuberculosis, Pulmonary | 1970 |
On the clinical effectiveness of Isoxyl.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Evaluation Studies as Topic; Follow-Up Studies; Humans; Isoniazid; Phenylthiourea; Tuberculosis, Pulmonary | 1970 |
Results and randomized original treatment in cases of pulmonary tuberculosis with isoniazid-streptomycin versus isoniazid-thiocarlide.
Topics: Adolescent; Adult; Drug Resistance, Microbial; Female; Humans; Isoniazid; Male; Middle Aged; Phenylthiourea; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1970 |
[Cooperative controlled trial of thiocarlide (DATC), PAS and bedrest alone in short-term single-drug treatment in retreated cavitary pulmonary tuberculosis].
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Humans; Phenylthiourea; Tuberculosis, Pulmonary | 1969 |
[Initial provisional record of a controlled trial of isoniazid-rifomycin-thiocarlide versus isoniazid-streptomycin-thiocarlide in active pulmonary tuberculosis not yet treated].
Topics: Clinical Trials as Topic; Drug Synergism; Humans; Isoniazid; Phenylthiourea; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1969 |
[Evaluation of the early results of chemotherapy of newly discovered pulmonary tuberculosis with the combination of streptomycin, isoniazid and isoxyl].
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Humans; Isoniazid; Phenylthiourea; Streptomycin; Tuberculosis, Pulmonary | 1968 |
[Long-term treatment of pulmonary tuberculosis; experiences with combination therapy using isoxyl].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Phenylthiourea; Tuberculosis, Pulmonary | 1966 |
A clinical trial of thiocarlide (4-4' diisoamyloxythiocarbanilide).
Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Humans; Male; Middle Aged; Phenylthiourea; Sputum; Tuberculosis, Pulmonary | 1966 |
49 other study(ies) available for thiocarlide and Tuberculosis--Pulmonary
Article | Year |
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Clinical experiences in cases of primary tuberculosis with tuberculostaticum Isoxyl.
Topics: Child, Preschool; Drug Combinations; Drug Synergism; Female; Humans; Infant; Isoniazid; Lung; Male; Phenylthiourea; Radiography; Streptomycin; Tuberculosis, Pulmonary | 1970 |
Isoxyl monotherapy.
Topics: Administration, Oral; Humans; Lung; Phenylthiourea; Radiography; Tuberculosis, Pulmonary | 1970 |
Clinical experience with thiocarlide (Isoxyl).
Topics: Adult; Aged; Chronic Disease; Drug Resistance, Microbial; Humans; Male; Middle Aged; Mycobacterium; Phenylthiourea; Sputum; Time Factors; Tuberculosis, Pulmonary | 1970 |
Clinical experiences with thiocarlide (Isoxyl) in combination therapy of freshly evaluated tuberculosis.
Topics: Aminosalicylic Acids; Drug Combinations; Drug Synergism; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Phenylthiourea; Streptomycin; Thiosemicarbazones; Tuberculosis; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary | 1970 |
Isoxyl: a review of the results of its use over a five-year period in the tuberculosis field service of a large urban area.
Topics: Adult; Aminosalicylic Acids; Cycloserine; Drug Combinations; Drug Resistance, Microbial; Ethionamide; Female; Humans; Ireland; Isoniazid; Male; Middle Aged; Phenylthiourea; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1970 |
Original course of chemotherapy in pulmonary tuberculosis with a double drug regimen: isoniazid-streptomycin versus isoniazid-thiocarlide.
Topics: Drug Combinations; Drug Resistance, Microbial; Evaluation Studies as Topic; Follow-Up Studies; Humans; Isoniazid; Phenylthiourea; Streptomycin; Time Factors; Tuberculosis, Pulmonary | 1970 |
[Activity of Isoxyl on Mycobacterium kansasii; studies in vitro and in the pneumoconiotic guinea pig].
Topics: Administration, Oral; Animals; Body Weight; Drug Combinations; Ethambutol; Ethionamide; Guinea Pigs; Isoniazid; Lung; Mycobacterium; Mycobacterium Infections; Phenylthiourea; Pneumoconiosis; Radiography; Time Factors; Tuberculosis, Pulmonary | 1970 |
Results of monotherapy with Isoxyl in untreated pulmonary tuberculosis cases of different difficulties and Isoxyl in routine-therapy.
Topics: Drug Resistance, Microbial; Humans; Phenylthiourea; Time Factors; Tuberculosis, Pulmonary | 1970 |
[Critical remarks on a clinical test of an antitubercular agent. Experiences with thiocarlide during collective work].
Topics: Drug Resistance, Microbial; Humans; Isoniazid; Mycobacterium tuberculosis; Phenylthiourea; Sputum; Tuberculosis, Pulmonary | 1969 |
A bacteriological study of thiocarlide monotherapy.
Topics: Analysis of Variance; Drug Resistance, Microbial; Humans; Phenylthiourea; Sputum; Tuberculosis, Pulmonary | 1969 |
[Isoxyl in the treatment of pulmonary tuberculosis].
Topics: Female; Humans; Isoniazid; Male; Phenylthiourea; Tuberculosis, Pulmonary | 1969 |
[Initial provisional record of treatment of relapses of active pulmonary tuberculosis with combined rifomycin, ethambutol and thiocarlide].
Topics: Adult; Aged; Drug Synergism; Ethambutol; Female; Humans; Male; Phenylthiourea; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1969 |
Experience of Isoxyl treatment.
Topics: Humans; Phenylthiourea; Tuberculosis, Pulmonary | 1968 |
[Results of use of Isoxyl in various combinations].
Topics: Antitubercular Agents; Ethambutol; Phenylthiourea; Tuberculosis, Pulmonary | 1967 |
[Results of treatment by a combination of thiocarlide and isoniazid in previously untreated pulmonary tuberculosis].
Topics: Adolescent; Adult; Aminosalicylic Acids; Female; Humans; Isoniazid; Male; Middle Aged; Phenylthiourea; Streptomycin; Tuberculosis, Pulmonary | 1967 |
[The resistance of Mycobacterium tuberculosis to ethionamide, thiosemicarbazone and isoxyl and their relations to each other].
Topics: Drug Resistance, Microbial; Ethionamide; Humans; Mycobacterium tuberculosis; Phenylthiourea; Thiosemicarbazones; Tuberculosis, Pulmonary | 1967 |
[Experience with te new antitubercular agents isoxyl, ethambutol, morphazinamid and rifomycin].
Topics: Culture Techniques; Cycloserine; Ethambutol; Humans; Isoniazid; Monocytes; Phenylthiourea; Pyrazines; Rifampin; Tuberculosis, Pulmonary | 1967 |
[Clinical experiences with INH-isoxyl therapy of primary tuberculosis].
Topics: Antitubercular Agents; Child; Child, Preschool; Drug Synergism; Humans; Infant; Isoniazid; Phenylthiourea; Tuberculosis; Tuberculosis, Pulmonary | 1967 |
[Therapeutic activity and tolerance of isoxyl in pulmonary tuberculosis].
Topics: Adult; Drug Tolerance; Female; Humans; Male; Middle Aged; Phenylthiourea; Tuberculosis, Pulmonary | 1966 |
[Clinical studies on the tuberculostatic activity of isoxyl].
Topics: Aminosalicylic Acids; Antitubercular Agents; Humans; Middle Aged; Phenylthiourea; Tuberculosis, Pulmonary | 1966 |
[On isoxyl treatment].
Topics: Adult; Antitubercular Agents; Female; Humans; Male; Phenylthiourea; Tuberculosis, Pulmonary | 1966 |
[CLINICAL FINDINGS ON 4,4'-DIISOAMYLOXYTHIOCARBANILIDE IN TUBERCULAR INFECTION].
Topics: Antitubercular Agents; Humans; Phenylthiourea; Tuberculosis; Tuberculosis, Pulmonary | 1965 |
CHEMOTHERAPY REGIMENS USED IN RETREATMENT OF PULMONARY TUBERCULOSIS. II. OBSERVATIONS ON THE EFFICACY OF COMBINATIONS OF ETHAMBUTOL, CAPREOMYCIN AND COMPANION DRUGS, INCLUDING 4-4 DIISOAMYLOXYTHIOSEMICARBANILIDE.
Topics: Antitubercular Agents; Capreomycin; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Ethambutol; Ethionamide; Kanamycin; Phenylthiourea; Pyrazinamide; Retreatment; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1965 |
A CONTROLLED TRIAL OF ISONIAZID AND 4-4 DIISOAMYLOXYTHIOSEMICARBANILIDE COMPARED WITH ISONIAZID AND PAS AND ISONIAZID, STREPTOMYCIN AND PAS.
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Drug Therapy; Geriatrics; Humans; Isoniazid; Phenylthiourea; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1965 |
[4-4'disioamyloxthiocarbanilide (Isoxyl) in the treatment of primo-infections in children and infants].
Topics: Animals; Antitubercular Agents; Child; Child, Preschool; Female; Guinea Pigs; Humans; Infant; Mice; Phenylthiourea; Tuberculosis, Pulmonary | 1965 |
Isoxyl.
Topics: Antitubercular Agents; Humans; Phenylthiourea; Tuberculosis, Pulmonary | 1965 |
[Isoxyl in the treatment of chronic lung tuberculosis].
Topics: Adult; Aged; Antitubercular Agents; Humans; Middle Aged; Phenylthiourea; Tuberculosis, Pulmonary | 1965 |
[ANTIMYCOBACTERIAL ACTIVITY OF ISOXYL. II. EXPERIMENTS WITH GUINEA PIGS AND RABBITS].
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Guinea Pigs; Isoniazid; Mycobacterium bovis; Mycobacterium tuberculosis; Pathology; Pharmacology; Phenylthiourea; Rabbits; Radiography, Thoracic; Research; Tuberculosis; Tuberculosis, Pulmonary; Tuberculosis, Splenic | 1964 |
["2ND LINE" DRUG THERAPY IN CHRONIC TUBERCULOSIS DUE TO GERM RESISTANCE. (NEW METHODS OF DRUG ADMINISTRATION; NEW DRUGS)].
Topics: Antitubercular Agents; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Humans; Phenylthiourea; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[ANTIMICROBIAL TREATMENT OF TUBERCULOSIS WITH SUBSIDIARY DRUGS. 2ND LINE DRUGS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Infective Agents; Antitubercular Agents; Bacteriology; Cycloserine; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Isoniazid; Kanamycin; Phenylthiourea; Pyrazinamide; Statistics as Topic; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Viomycin | 1964 |
[TRIAL OF 4,4'-DIISOAMYLOXYTHIOCARBANILIDE IN THE TREATMENT OF PULMONARY TUBERCULOSIS].
Topics: Antitubercular Agents; Pharmacology; Phenylthiourea; Radiography; Statistics as Topic; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[ASSOCIATION OF 4,4'-DIISOAMYLOXYTHIOCARBANILIDE AND PYRAZINAMIDE, AND 4,4'-DIISOAMYLOXYTHIOCARBANILIDE AND KANAMYCIN IN THE TREATMENT OF PULMONARY TUBERCULOSIS CAUSED BY BACTERIA RESISTANT TO THE 1ST LINE DRUGS].
Topics: Antitubercular Agents; Bacteria; Bacteriology; Drug Resistance; Drug Resistance, Microbial; Kanamycin; Phenylthiourea; Pyrazinamide; Radiography, Thoracic; Sputum; Toxicology; Tuberculosis, Pulmonary | 1964 |
MONOTHERAPY WITH 4-4'DIISOAMYLOXYTHIO-CARBANILIDE (ISOXYL).
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Biomedical Research; Blood Sedimentation; Body Temperature; Body Weight; Carbanilides; Drug Resistance; Drug Resistance, Microbial; Gastric Lavage; Isoniazid; Phenylthiourea; Sputum; Statistics as Topic; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[D.A.T.C. IN PULMONARY TUBERCULOSIS IN NON-TREATED PATIENTS].
Topics: Antitubercular Agents; Argentina; Drug Resistance; Drug Resistance, Microbial; Humans; Isoniazid; Phenylthiourea; Radiography, Thoracic; Sputum; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[STUDY IN VITRO OF 4-4'-DIISOAMYLOXYTHIOCARBANILIDE ON COLONIES OF MYCOBACTERIUM TUBERCULOSIS ISOLATED FROM TUBERCULOUS PATIENTS].
Topics: Antitubercular Agents; Humans; In Vitro Techniques; Mycobacterium tuberculosis; Pharmacology; Phenylthiourea; Research; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[TREATMENT TRIALS IN PULMONARY TUBERCULOSIS COMBINING ISONIAZID, ADMINISTERED 2 TIMES A WEEK, AND A THIOCARBANILIDE IN DAILY FORM].
Topics: Anilides; Antitubercular Agents; Biomedical Research; Drug Resistance; Drug Resistance, Microbial; Isoniazid; Phenylthiourea; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[CLINICAL EXPERIENCE WITH D.A.T.C].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Drug Resistance; Drug Resistance, Microbial; Erythromycin; Isoniazid; Pharmacology; Phenylthiourea; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[EXPERIENCE IN PULMONARY TUBERCULOSIS WITH D.A.T.C. RESULTS IN 15 PATIENTS WITHOUT PREVIOUS TREATMENT].
Topics: Antitubercular Agents; Phenylthiourea; Radiography, Thoracic; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[TREATMENT OF PULMONARY TUBERCULOSIS WITH SUBSIDIARY DRUGS].
Topics: Antitubercular Agents; Humans; Isoniazid; Phenylthiourea; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
CLINICAL EXPERIENCE OF ISOXYL.
Topics: Antitubercular Agents; Biometry; Drug Therapy; Humans; Phenylthiourea; Statistics as Topic; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[ISOXYL, IN COMBINATION WITH OTHER ANTIMYCOBACTERIAL DRUGS, IN THE THERAPY OF CHRONIC PULMONARY TUBERCULOSIS].
Topics: Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy; Humans; Phenylthiourea; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
CONTROLLED CLINICAL TRIAL OF 4-4 DIISOAMYLOXYTHIOCARBANILIDE IN THE TREATMENT OF PULMONARY TUBERCULOSIS.
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Asian People; Bacteriological Techniques; Biomedical Research; Blood Chemical Analysis; China; Drug Resistance; Drug Resistance, Microbial; Ethionamide; Intestinal Absorption; Isoniazid; Phenylthiourea; Radiography, Thoracic; Sputum; Streptomycin; Thiosemicarbazones; Toxicology; Tuberculosis, Pulmonary | 1964 |
[ALLERGOMETRY, SEDIMENTATION VELOCITY, SERUM AGGLUTININS AND ELECTROPHORETIC PICTURE IN THE USE OF 4-4'-DIISOAMYLOXYTHIOCARBANILID IN THE TREATMENT OF PULMONARY TUBERCULOSIS].
Topics: Agglutinins; Antitubercular Agents; Biomedical Research; Blood Protein Electrophoresis; Blood Sedimentation; Drug Therapy; Electrophoresis; Hemagglutination; Humans; Phenylthiourea; Tuberculosis; Tuberculosis, Pulmonary | 1964 |
[Clinical experiences with 2 new antitubercular agents: ethioniamide (iridoncin) and diisoamylhydroxythiocarbanilide (isoxyl)].
Topics: Antitubercular Agents; Ethionamide; Phenylthiourea; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
[Isoxyl in the treatment of pulmonary tuberculosis].
Topics: Analgesics; Anilides; Antitubercular Agents; Phenylthiourea; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
[PRELIMINARY REPORT ON CLINICAL FINDINGS ON THE COMBINED TREATMENT OF PULMONARY TUBERCULOSIS WITH ISOXYL, A NEW TUBERCULOSTATIC].
Topics: Antitubercular Agents; Combined Modality Therapy; Cycloserine; Humans; Isoniazid; Oxytetracycline; Phenylthiourea; Prednisolone; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
[CLINICAL EXPERIENCE WITH 4,4'-DIISOAMYLOXYTHIOCARBANILIDE (ISOXYL) IN PULMONARY TUBERCULOSIS].
Topics: Antitubercular Agents; Humans; Phenylthiourea; Tuberculosis, Pulmonary | 1963 |
THE EFFECTIVENESS OF A THIOCARBANILIDE (ISOXYL) AS A THERAPEUTIC DRUG IN MOUSE TUBERCULOSIS.
Topics: Analgesics; Anilides; Animals; Antitubercular Agents; Mice; Phenylthiourea; Research; Tuberculosis; Tuberculosis, Pulmonary | 1963 |
[Preliminary report on treatment of pulmonary tuberculosis with Isoxyl].
Topics: Phenylthiourea; Thiourea; Tuberculosis; Tuberculosis, Pulmonary | 1961 |