thioacetazone and Hypoxia

thioacetazone has been researched along with Hypoxia* in 1 studies

Other Studies

1 other study(ies) available for thioacetazone and Hypoxia

Article	Year
[Isoniazid acetylation, its relation to genetic and environmental altitude factors]. Archivos de biologia y medicina experimentales, 1987, Volume: 20, Issue:1 Since the discovery of isoniacid in 1952, it has become apparent that there are considerable variations in the manner in which individuals react to the drug. We studied 90 patients from La Paz (3.600 m. over sea level) and 50 patients from Santa Cruz (470 m. over sea level). Our results in the two groups tested suggest that the high altitude hypoxia increases the velocity of inactivation. Despite to the influence of hypoxia it was seen that both groups have the some frequency of rapid and slow inactivators. Topics: Acetylation; Adolescent; Adult; Aged; Altitude; Antitubercular Agents; Arylamine N-Acetyltransferase; Biotransformation; Bolivia; Child; Drug Therapy, Combination; Female; Humans; Hypoxia; Isoniazid; Kinetics; Liver; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Streptomycin; Thioacetazone; Tuberculosis	1987

Article

Year

[Isoniazid acetylation, its relation to genetic and environmental altitude factors].

Archivos de biologia y medicina experimentales, 1987, Volume: 20, Issue:1

Since the discovery of isoniacid in 1952, it has become apparent that there are considerable variations in the manner in which individuals react to the drug. We studied 90 patients from La Paz (3.600 m. over sea level) and 50 patients from Santa Cruz (470 m. over sea level). Our results in the two groups tested suggest that the high altitude hypoxia increases the velocity of inactivation. Despite to the influence of hypoxia it was seen that both groups have the some frequency of rapid and slow inactivators.

Topics: Acetylation; Adolescent; Adult; Aged; Altitude; Antitubercular Agents; Arylamine N-Acetyltransferase; Biotransformation; Bolivia; Child; Drug Therapy, Combination; Female; Humans; Hypoxia; Isoniazid; Kinetics; Liver; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Streptomycin; Thioacetazone; Tuberculosis

1987