Compounds > thiethylperazine
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thiethylperazine and Vomiting

thiethylperazine has been researched along with Vomiting in 50 studies

Thiethylperazine: A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
thiethylperazine : A member of the class of phenothiazines that is perazine substituted by a ethylsulfanyl group at position 2.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone."7.68The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990)
"A double-blind study of thiethylperazine dimaleate (Torecan) and a placebo, given intramuscularly, was carried out on 40 patients with nausea and/or vomiting due to a variety of causes."7.64THE EFFECTS OF THIETHYLPERAZINE DIMALEATE (TORECAN) ON NAUSEA AND VOMITING. ( BOGOCH, A; MCGILLIVRAY, DC; TAMBOLINE, BL, 1965)
"Thiethylperazine is a commonly used anti-emetic drug during pregnancy in Hungary."3.72Case-control study of teratogenic potential of thiethylperazine, an anti-emetic drug. ( Czeizel, AE; Vargha, P, 2003)
"Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone."3.68The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990)
"The author summarizes the theoretical aspects of vomiting and alleviation of the same by surveying the respective scientific communications with special regard to thiethylperazine."3.68Torecan, a review of references and clinical control examinations. ( Rádi, A, 1990)
"A double-blind study of thiethylperazine dimaleate (Torecan) and a placebo, given intramuscularly, was carried out on 40 patients with nausea and/or vomiting due to a variety of causes."3.64THE EFFECTS OF THIETHYLPERAZINE DIMALEATE (TORECAN) ON NAUSEA AND VOMITING. ( BOGOCH, A; MCGILLIVRAY, DC; TAMBOLINE, BL, 1965)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199044 (88.00)18.7374
1990's5 (10.00)18.2507
2000's1 (2.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Czeizel, AE1
Vargha, P1
COX, J1
COLLINS, JH1
MUNIZ, H1
ZUG, CK1
PITT, LP1
ALBARRACIN, A1
MARCOS, JF1
MIRANDA, M1
PIGNATELLI, F1
DONOVAN, J1
REBECCHI, M1
VACCARI, F1
BRIZZEE, KR1
GIBSON, KB1
HARRER, G1
NEWLINDS, JS1
THOMSEN, M1
DE OLIVEIRA, I1
GARDIN, L1
MARCZYNSKI, K1
KRAJEWSKI, W1
PADDOCK, RB1
KOLODNY, AL1
TAMBOLINE, BL1
MCGILLIVRAY, DC1
BOGOCH, A1
FUKAI, H1
YAJIMA, K1
LIMA, OC1
MALTA, MT1
JORGEFILHO, JE1
Dilşen, N1
Miturzyńska-Stryjecka, H1
Plezia, PM2
Alberts, DS2
Kessler, J1
Aapro, MS1
Graham, V1
Surwit, EA1
Cooper, JR1
Mattsson, JL1
Martin, M1
Diaz-Rubio, E2
Casado, A1
Dominguez, S1
Sastre, J1
Kessler, JF1
Berens, PL1
Chase, JL1
Roe, DJ1
Hoffman, GS1
Leavitt, RY1
Fleisher, TA1
Minor, JR1
Fauci, AS1
Lencz, L1
Rádi, A1
Martin-Jimenez, M1
Sangro, B1
Cordts, RE1
Yochmowitz, MG1
Hardy, KA1
Hertrich, O1
Lutz, H2
Immich, H1
Mammel, E1
Somody, L1
Póka, L1
Mendoza, CB1
Gerwig, WH1
Holt, JA1
Battersby, C1
Khanna, SK1
Anand, SS1
Saini, VK1
Kurohara, SS1
George, FW1
Levitts, S1
Rubin, P1
Purkis, IE1
Rae, JL1
Flock, ER1
Royce, RD1
Buller, RL1
Ingram, MH1
Lewiński, A1
Wajda, Z1
Banasik, Z1
Karasiewicz-Kucharska, K1
Gruca, Z1
Bross, W1
Olejak, B1
Bross, T1
Kotowski, R1
Kustrzycki, A1
Wrezlewicz, W1
Sicher, K1
Backhouse, TW1
Oknińska, H1
Pecoldowa, K1
Tsuru, M1
Takeda, T1
Arlía, R1
Bauer, A1
Klabal, F1

Trials

10 trials available for thiethylperazine and Vomiting

ArticleYear
Randomized crossover comparison of high-dose intravenous metoclopramide versus a five-drug antiemetic regimen.
    Journal of pain and symptom management, 1990, Volume: 5, Issue:2

    Topics: Adult; Aged; Cisplatin; Dexamethasone; Diazepam; Diphenhydramine; Drug Therapy, Combination; Humans;

1990
Results of two controlled studies on antiemetic combination against vomiting induced by 5-fluorouracil.
    Tumori, 1987, Oct-31, Volume: 73, Issue:5

    Topics: Adult; Aged; Amitriptyline; Antiemetics; Clinical Trials as Topic; Diphenhydramine; Drug Therapy, Co

1987
Antiemetic effect of benzquinamide in postoperative vomiting.
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Aged; Amides; Antiemetics; Blood Pressure; Clinical Trials as Topic; Fatigue; Fem

1972
A clinical trial of thiethylperazine ("Torecan") suppositories in postoperative nausea and vomiting.
    The Medical journal of Australia, 1965, Sep-11, Volume: 2, Issue:11

    Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Humans; Middle Aged; Nausea; Placebos; Pos

1965
Control of postoperative vomiting by thiethylperazine.
    Journal of the Indian Medical Association, 1965, Dec-01, Volume: 45, Issue:11

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Animals; Child; Child, Preschool; Clinical Trials a

1965
Factor concerned with "clinical radiation nausea".
    Radiology, 1966, Volume: 86, Issue:2

    Topics: Antiemetics; Clinical Trials as Topic; Female; Humans; Male; Nausea; Placebos; Psychology; Radiation

1966
The action of thiethylperazine (Torecan), a new anti-emetic, compared with perphenazine (Trilafon), trimethobenzamide (Tigan), and a placebo in the suppression of postanaesthetic nausea and vomiting.
    Canadian Anaesthetists' Society journal, 1965, Volume: 12, Issue:6

    Topics: Benzamides; Clinical Trials as Topic; Humans; Perphenazine; Placebos; Postoperative Complications; T

1965
Trial of thiethylperazine ("torecan") for the prevention of postoperative vomiting.
    The Medical journal of Australia, 1967, Jun-03, Volume: 1, Issue:22

    Topics: Clinical Trials as Topic; Humans; Injections, Intramuscular; Nausea; Placebos; Postoperative Complic

1967
The effect of thiethylperazine on nausea, vomiting and vertigo.
    The Journal of the Oklahoma State Medical Association, 1966, Volume: 59, Issue:9

    Topics: Adolescent; Adult; Aged; Antiemetics; Child; Clinical Trials as Topic; Female; Humans; Male; Middle

1966
An assessment of thiethylperazine (Torecan) in the control of radiation-induced nausea and vomiting.
    Clinical radiology, 1968, Volume: 19, Issue:2

    Topics: Antiemetics; Humans; Nausea; Neoplasms; Pyridoxine; Radiotherapy; Thiethylperazine; Vomiting

1968

Other Studies

40 other studies available for thiethylperazine and Vomiting

ArticleYear
Case-control study of teratogenic potential of thiethylperazine, an anti-emetic drug.
    BJOG : an international journal of obstetrics and gynaecology, 2003, Volume: 110, Issue:5

    Topics: Abnormalities, Drug-Induced; Antiemetics; Case-Control Studies; Cleft Palate; Female; Humans; Hungar

2003
Nausea and vomiting: control by thiethylperazine.
    Current therapeutic research, clinical and experimental, 1962, Volume: 4

    Topics: Humans; Nausea; Thiethylperazine; Tranquilizing Agents; Vomiting

1962
Thiethylperazine for the prevention of postoperative nausea and vomiting.
    Current therapeutic research, clinical and experimental, 1963, Volume: 5

    Topics: Antiemetics; Biomedical Research; Humans; Nausea; Postoperative Nausea and Vomiting; Surgical Proced

1963
[Treatment of vomiting with a new antiemetic: thiethylperazine (Thorecan)].
    Medicina espanola, 1962, Volume: 48

    Topics: Antiemetics; Thiethylperazine; Tranquilizing Agents; Vomiting

1962
Radiation sickness and its control with thiethylperazine ("Torecan"): a preliminary evaluation.
    The Medical journal of Australia, 1963, Apr-27, Volume: 1

    Topics: Humans; Radiation Injuries; Thiethylperazine; Tranquilizing Agents; Vomiting

1963
[CLINICAL RESEARCH ON A NEW DRUG WITH ANTIEMETIC AND ANTIVERTIGINOUS ACTION].
    Gazzetta internazionale di medicina e chirurgia, 1963, Aug-15, Volume: 67

    Topics: Antiemetics; Biomedical Research; Gallbladder Diseases; Humans; Liver Diseases; Meniere Disease; Sto

1963
ANTI-EMETIC ACTION OF THIETHYLPERAZINE. EXPERIMENTAL FINDINGS.
    Archives internationales de pharmacodynamie et de therapie, 1963, Nov-01, Volume: 146

    Topics: Antiemetics; Dogs; Pharmacology; Research; Thiethylperazine; Tranquilizing Agents; Vomiting

1963
[ON THE SYMPTOMATIC TREATMENT OF VOMITING AND VERTIGO].
    Wiener klinische Wochenschrift, 1963, Sep-27, Volume: 75

    Topics: Antiemetics; Humans; Meniere Disease; Nausea; Phenothiazines; Thiethylperazine; Vertigo; Vomiting

1963
NAUSEA AND VOMITING IN PREGNANCY: A TRIAL OF THIETHYLPERAZINE.
    The Medical journal of Australia, 1964, Feb-15, Volume: 1

    Topics: Antiemetics; Dosage Forms; Female; Humans; Hyperemesis Gravidarum; Nausea; Pharmacology; Pregnancy;

1964
[TORECAN, A NEW ANTIEMETIC USED IN POSTOPERATIVE NAUSEA AND VOMITING].
    Ugeskrift for laeger, 1964, Apr-09, Volume: 126

    Topics: Antiemetics; Biomedical Research; Chlorpromazine; Humans; Nausea; Placebos; Postoperative Complicati

1964
[RADIATION SICKNESS AND THE INTEGRAL DOSE. (ANTIEMETIC ACTION OF "TORECAN")].
    Jornal do medico, 1964, Jun-27, Volume: 54

    Topics: Antiemetics; Humans; Neoplasms; Radiation Injuries; Radiotherapy Dosage; Thiethylperazine; Vomiting

1964
[THE THERAPY OF VOMITING IN PREGNANCY. CLINICAL CONTRIBUTION].
    Rivista di ostetricia e ginecologia, 1964, Volume: 19

    Topics: Antiemetics; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Thiethylperazine; Vomiting

1964
[CLINICAL EVALUATION OF TORECAN THERAPY OF VOMITING IN PREGNANCY].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1964, Feb-17, Volume: 19

    Topics: Drug Therapy; Female; Humans; Pregnancy; Pregnancy Complications; Thiethylperazine; Vomiting

1964
THIETHYLPERAZINE IN THE MANAGEMENT OF POSTOPERATIVE NAUSEA AND VOMITING.
    The Journal of the International College of Surgeons, 1964, Volume: 42

    Topics: Anesthetics; Biomedical Research; Drug Therapy; Geriatrics; Humans; Injections, Intravenous; Nausea;

1964
THIETHYLPERAZINE FOR THE CONTROL OF VOMITING. A DOUBLE-BLIND STUDY.
    The American journal of gastroenterology, 1964, Volume: 42

    Topics: Antiemetics; Biomedical Research; Double-Blind Method; Drug Therapy; Humans; Suppositories; Tablets;

1964
THE EFFECTS OF THIETHYLPERAZINE DIMALEATE (TORECAN) ON NAUSEA AND VOMITING.
    Canadian Medical Association journal, 1965, Feb-20, Volume: 92

    Topics: Biomedical Research; Double-Blind Method; Drug Therapy; Humans; Injections, Intramuscular; Nausea; P

1965
[ANTIEMETIC EFFECT OF THIETHYLPERAZINE FOR NAUSEA AND VOMITING ASSOCIATED WITH PNEUMOENCEPHALOGRAPHY].
    No to shinkei = Brain and nerve, 1964, Volume: 16

    Topics: Antiemetics; Cerebral Ventriculography; Diagnostic Imaging; Drug Therapy; Humans; Nausea; Pneumoence

1964
[VOMITING IN PREGNANCY. PREVENTION AND TREATMENT].
    Hospital (Rio de Janeiro, Brazil), 1965, Volume: 67

    Topics: Biomedical Research; Drug Therapy; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Thiethylperazi

1965
[Thiethylperazine in the treatment of vertigo, nausea and vomiting in internal medicine].
    Turk Tip Cemiyeti mecmuasi, 1967, Volume: 33, Issue:1

    Topics: Humans; Nausea; Thiethylperazine; Vertigo; Vomiting

1967
[Clinical evaluation of the drug Torecan].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1967, Jul-17, Volume: 22, Issue:29

    Topics: Female; Humans; Male; Nausea; Thiethylperazine; Vertigo; Vomiting

1967
Immediate termination of intractable vomiting induced by cisplatin combination chemotherapy using an intensive five-drug antiemetic regimen.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Diazepam; Dip

1984
Control of radiation-induced emesis with promethazine, cimetidine, thiethylperazine, or naloxone.
    American journal of veterinary research, 1979, Volume: 40, Issue:8

    Topics: Animals; Chemoreceptor Cells; Cimetidine; Dog Diseases; Dogs; Guanidines; Male; Naloxone; Promethazi

1979
Progressive loss of antiemetic efficacy during subsequent courses of chemotherapy.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28, Issue:2-3

    Topics: Adult; Aged; Amitriptyline; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cyclophosph

1992
Treatment of Wegener's granulomatosis with intermittent high-dose intravenous cyclophosphamide.
    The American journal of medicine, 1990, Volume: 89, Issue:4

    Topics: Adult; Aged; Cyclophosphamide; Drug Administration Schedule; Female; Granulomatosis with Polyangiiti

1990
The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting.
    Therapia Hungarica (English edition), 1990, Volume: 38, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Dimenhydrinate; Domperidone; Femal

1990
Torecan, a review of references and clinical control examinations.
    Therapia Hungarica (English edition), 1990, Volume: 38, Issue:2

    Topics: Adolescent; Child; Drug Evaluation; Female; Humans; Male; Nausea; Pregnancy; Pyridoxine; Thiethylper

1990
Evaluation of domperidone as a modifier of gamma-radiation-induced emesis.
    International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:9

    Topics: Animals; Antiemetics; Cimetidine; Cobalt Radioisotopes; Dexamethasone; Dogs; Domperidone; Drug Thera

1987
[Neuroleptics, thymoleptics and tranquilizers in neurological therapy].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Basal Ganglia Diseases; Chlordiazepoxide; Chlorpromazine; Diazepam; Epilepsy; Extrapyramidal Tracts;

1969
Use of Torecan (thiethylperazine) in surgery.
    Therapia Hungarica (English edition), 1971, Volume: 19, Issue:2

    Topics: Bile Ducts; Humans; Injections, Intramuscular; Postoperative Complications; Stomach; Suppositories;

1971
Effect of thiethylperazine as prophylaxis for nausea and vomiting in surgery.
    The Journal of the American Association of Nurse Anesthetists, 1968, Volume: 36, Issue:2

    Topics: Nausea; Nursing; Thiethylperazine; Vomiting

1968
A trial of thiethylperazine ("Torecan") in patients suffering from radiation sickness.
    The Medical journal of Australia, 1965, Aug-14, Volume: 2, Issue:7

    Topics: Dimenhydrinate; Feeding and Eating Disorders; Humans; Nausea; Neoplasms; Pyridoxine; Radiation Injur

1965
[Effect of torecan on vomiting in postoperative period].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1970, Feb-01, Volume: 23, Issue:3

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Postoperative Complications; Thiethylperazine; Vomit

1970
[Treatment of postoperative vomiting].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1970, Aug-01, Volume: 23, Issue:15

    Topics: Adolescent; Adult; Blood Pressure; Dehydration; Female; Humans; Male; Middle Aged; Postoperative Com

1970
[Clinical use of torecan with particular reference to the prevention of postoperative nausea and vomiting].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1968, Feb-05, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Anesthesia, General; Humans; Nausea; Postoperative Complications; Thiethylperazin

1968
[Prevention of nausea and vomiting and their therapy with Torecan after ophthalmic surgery].
    Klinika oczna, 1968, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Nausea; Ophthalmologic Surgical Procedur

1968
[Clinical experiences with thiethylperazine dimaleate (Toresten)].
    No to shinkei = Brain and nerve, 1965, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Blood Pressure; Brain Diseases; Child; Female; Humans; Male; Meniere Disease; Mid

1965
[The use of thiethylperazine in control of postoperative vomiting].
    Prensa medica argentina, 1966, May-06, Volume: 53, Issue:18

    Topics: Humans; Postoperative Complications; Thiethylperazine; Vomiting

1966
Antiemetic effect of thiethylperazine (Torecan) in connexion with surgery.
    Acta chirurgica Scandinavica, 1966, Volume: 132, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthetics; Atropine; Chlordiazepoxide; Female; Humans; Male; Middle Aged;

1966
[On the prevention of nausea and vomiting in the early postoperative phase].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1966, Volume: 37, Issue:1

    Topics: Humans; Nausea; Postoperative Complications; Thiethylperazine; Vomiting

1966
[Contribution to the therapy of vomiting and hyperemesis gravidarum].
    Zentralblatt fur Gynakologie, 1966, Sep-10, Volume: 88, Issue:37

    Topics: Adult; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Thiethylperazine; Vomiting

1966