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thiethylperazine and Neuroleptic Malignant Syndrome

thiethylperazine has been researched along with Neuroleptic Malignant Syndrome in 1 studies

Thiethylperazine: A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
thiethylperazine : A member of the class of phenothiazines that is perazine substituted by a ethylsulfanyl group at position 2.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
" We describe a case in a 52-year-old diabetic woman who developed NMS after taking Torecan (thiethylperazine), a phenothiazine drug, for 3 months to relieve dizziness."3.68[Torecan-induced neuroleptic malignant syndrome]. ( Bulvik, S; Kaplan, CL; Shimoni, Z, 1990)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bulvik, S1
Shimoni, Z1
Kaplan, CL1

Other Studies

1 other study available for thiethylperazine and Neuroleptic Malignant Syndrome

ArticleYear
[Torecan-induced neuroleptic malignant syndrome].
    Harefuah, 1990, May-15, Volume: 118, Issue:10

    Topics: Dizziness; Female; Humans; Middle Aged; Neuroleptic Malignant Syndrome; Thiethylperazine

1990