Page last updated: 2024-11-05

thiethylperazine and Cleft Palate

thiethylperazine has been researched along with Cleft Palate in 3 studies

Thiethylperazine: A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
thiethylperazine : A member of the class of phenothiazines that is perazine substituted by a ethylsulfanyl group at position 2.

Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.

Research Excerpts

ExcerptRelevanceReference
"An increased risk for isolated CL/P was found in cases born to mothers treated with amoxicillin, phenytoin, oxprenolol, and thiethylperazine during the second and third month of pregnancy, i."3.74Drug treatment during pregnancy and isolated orofacial clefts in hungary. ( Czeizel, AE; Métneki, J; Puhó, EH; Szunyogh, M, 2007)
"Thiethylperazine is a commonly used anti-emetic drug during pregnancy in Hungary."3.72Case-control study of teratogenic potential of thiethylperazine, an anti-emetic drug. ( Czeizel, AE; Vargha, P, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Czeizel, AE2
Vargha, P1
Puhó, EH1
Szunyogh, M1
Métneki, J1
Szabo, KT1
Brent, RL1

Other Studies

3 other studies available for thiethylperazine and Cleft Palate

ArticleYear
Case-control study of teratogenic potential of thiethylperazine, an anti-emetic drug.
    BJOG : an international journal of obstetrics and gynaecology, 2003, Volume: 110, Issue:5

    Topics: Abnormalities, Drug-Induced; Antiemetics; Case-Control Studies; Cleft Palate; Female; Humans; Hungar

2003
Drug treatment during pregnancy and isolated orofacial clefts in hungary.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2007, Volume: 44, Issue:2

    Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Amoxicillin; Anti-Bacterial Agents; Antico

2007
Letter: Species differences in experimental teratogenesis by tranquillising agents.
    Lancet (London, England), 1974, Mar-30, Volume: 1, Issue:7857

    Topics: Abnormalities, Drug-Induced; Animals; Antipsychotic Agents; Cleft Palate; Dose-Response Relationship

1974