thienopyridine has been researched along with Pain* in 1 studies
1 other study(ies) available for thienopyridine and Pain
| Article | Year |
|---|---|
Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity.
5-Methyl-6-phenyl-2-thioxothieno[2,3-d]pyrimidone derivative (2) reacted with hydrazonoyl chloride derivatives to afford triazolothienopyrimidones 4a-f. Also, acetone-1-(2-amino-5-isopropyl-thiophene-3-carbonitrile) (3) reacted with functional and bifunctional groups to yield the corresponding compounds 5-11. The new products showed anti-inflammatory, analgesic, and ulcerogenic activities comparable to that of indomethacin and acetylsalicylic acid, respectively. Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Disease Models, Animal; Female; Indomethacin; Inflammation; Male; Mice; Molecular Structure; Pain; Pain Measurement; Pain Threshold; Pyridines; Rats; Stomach Ulcer; Structure-Activity Relationship | 2007 |