thiazolyl blue has been researched along with Alzheimer Disease in 43 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (6.98) | 18.2507 |
2000's | 24 (55.81) | 29.6817 |
2010's | 15 (34.88) | 24.3611 |
2020's | 1 (2.33) | 2.80 |
Authors | Studies |
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Beloglazkina, E; Erofeev, A; Gorelkin, P; Guk, D; Krasnovskaya, O; Majouga, A; Naumov, A | 1 |
Al-Owais, MM; Boyle, JP; Dallas, ML; Hettiarachchi, NT; Peers, C; Scragg, JL | 1 |
Bao, L; Dong, H; Feng, X; Gao, Q; Gao, Y; Hao, J; Liang, N; Liu, H; Peng, L; Sun, J; Yu, X; Yue, Q; Zhang, J; Zhu, D | 1 |
Gu, L; Guo, Z; Liu, C | 1 |
Campos, C; Gil, P; Guzmán, R; Masegù, C; Moragón, ÁC; Yuguero, R | 1 |
Fändrich, M; Klemm, A; Meinhardt, J; Reymann, KG; Rönicke, R; Schröder, UH | 1 |
Amadio, M; Gandy, S; Haroutunian, V; Ho, L; Pascale, A; Pasinetti, GM; Quattrone, A; Racchi, M; Wang, J | 1 |
Ba, MW; Sun, ZK; Xing, Y; Xu, J; Yang, HQ | 1 |
Bradley, J; Mayne, M; Noonan, C; Richard, K; Supnet, C | 1 |
Chang, KH; de Pablo, Y; Lee, HG; Lee, HP; Shah, K; Smith, MA | 1 |
Hao, J; Lei, G; Li, Z; Liu, L; Liu, R; Miao, J; Su, C; Zhang, P; Zhang, W | 1 |
Cardoso, SM; Costa, RO; Ferreiro, E; Martins, I; Oliveira, CR; Pereira, CM; Santana, I | 1 |
Chen, W; Fang, M; Geng, Y; Han, S; Hu, Z; Ling, S; Rudd, JA; Wang, J; Zhang, X | 1 |
Bi, BT; Cheng, YF; Li, TJ; Lin, HB; Lin, T; Xu, JP; Zhang, MZ; Zhou, H | 1 |
Liu, RT; Wang, L; Wang, SW; Wang, YJ; Xue, D; Yang, Y; Zhang, R; Zhao, M; Zhao, Y | 1 |
Altman, R; Bricarello, DA; Harishchandra, G; Hideg, K; Hong, HS; Jin, LW; Kálai, T; Lorigan, GA; Maezawa, I; Parikh, AN; Petrlova, J; Voss, JC | 1 |
Bradley, MA; Fister, SX; Lovell, MA | 1 |
Akaike, A; Irie, K; Izumi, Y; Izuo, N; Kume, T; Murakami, K; Sato, M | 1 |
Li, YN; Liu, RT; Su, YJ; Wang, SW; Yang, SG; Yu, XL; Zhang, H; Zhang, R; Zhao, M; Zhou, WW | 1 |
Futaki, S; Hamada, H; Iida, S; Masliah, E; Matoh, N; Sugiura, Y; Suzuki, T; Takehashi, M; Tanaka, S; Ueda, K | 1 |
Chen, XL; Hu, HT; Liu, Y; Qian, YH; Ren, HM; Xu, JH | 1 |
Irie, K; Morimoto, A; Murakami, K; Nagao, M; Ohigashi, H; Shimizu, T; Shindo, M; Shirasawa, T | 1 |
Hasegawa, K; Naiki, H; Ono, K; Takashima, A; Yamada, M; Yoshiike, Y | 1 |
Andreoni, S; Appollonio, I; Begni, B; Beretta, S; Brighina, L; Ferrarese, C; Fumagalli, L; Isella, V; Malaplate-Armand, C; Oster, T; Sirtori, E | 1 |
de las Cuevas, N; Hermida, OG; Martín-Requero, A; Muñoz, U | 1 |
Chung, KC; Kim, J; Lee, CH; Lee, HJ; Lee, ST; Oh, YJ; Paik, SR; Park, SM; Sung, JY; Um, JW | 1 |
He, Y; Luo, Y; Tang, H; Zhou, H | 1 |
Baglioni, S; Bagnoli, S; Cecchi, C; Fiorillo, C; Liguri, G; Nacmias, B; Nosi, D; Pensalfini, A; Relini, A; Sorbi, S | 1 |
Bigio, EH; Chang, L; De Felice, FG; Fernandez, S; Gong, Y; Khuon, D; Klein, WL; Krafft, GA; Lacor, PN; Lambert, MP; Shaw, P; Velasco, PT; Viola, KL | 1 |
Elstner, EF; Heilmann, J; Kraus, B; Wolff, H | 1 |
Hadjipavlou-Litina, D; Kontogiorgis, CA; Luo, Y; Xu, Y | 1 |
Datki, ZL; Földi, I; Hunya, A; Penke, B; Soós, K; Szabó, A; Szegedi, V; Zádori, D; Zarándi, M | 1 |
Butterfield, DA; Drake, J; Green, M; Jordan, B; Koppal, T; Subramaniam, R; Yatin, S | 1 |
Butterfield, DA; Koppal, T; Varadarajan, S; Yatin, SM | 1 |
George, AR; Howlett, DR; Markwell, RE; Owen, DE; Ward, RV | 1 |
Ankarcrona, M; Benedikz, E; Cowburn, RF; Flood, F; Mehta, ND; Nilsberth, C; Perez-Tur, J; Tanii, H; Winblad, B | 1 |
Bodles, AM; Campbell, P; Guthrie, DJ; Harriott, P; Irvine, GB | 1 |
Ihara, Y; Misonou, H; Morishima-Kawashima, M | 1 |
Fu, Y; Tang, XC; Zhou, J | 1 |
Barker, JL; Chang, Y; Li, BS; Ma, W; Maric, D; Rubinow, DR; Xing, GQ; Zhang, L | 1 |
Baysang, G; Brockhaus, M; Hess, C; Ly, C; Meier, F; Müller-Spahn, F; Olivieri, G; Savaskan, E | 1 |
Daniels, WM; Hendricks, J; Salie, R; Taljaard, JJ | 1 |
Eckert, A; Haass, C; Leutz, S; Marques, CA; Müller, WE; Steiner, B | 1 |
1 review(s) available for thiazolyl blue and Alzheimer Disease
Article | Year |
---|---|
Copper Coordination Compounds as Biologically Active Agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Infective Agents; Antineoplastic Agents; Biological Factors; Cell Line, Tumor; Copper; Drug Design; Drug Evaluation, Preclinical; Flow Cytometry; HEK293 Cells; Humans; Inhibitory Concentration 50; Ions; Isotopes; Ligands; MCF-7 Cells; Mycobacterium tuberculosis; Oxidation-Reduction; Positron-Emission Tomography; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tuberculosis | 2020 |
42 other study(ies) available for thiazolyl blue and Alzheimer Disease
Article | Year |
---|---|
Heme oxygenase-1 derived carbon monoxide suppresses Aβ
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Antioxidants; Astrocytes; Carbon Monoxide; Heme Oxygenase (Decyclizing); Homeostasis; Neurons; Nitric Oxide; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2017 |
Resveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Calcium; Cell Survival; Flow Cytometry; Gene Expression Regulation; Homeostasis; L-Lactate Dehydrogenase; Neurodegenerative Diseases; Neurons; PC12 Cells; Peptide Fragments; Rats; Resveratrol; rho-Associated Kinases; Signal Transduction; Sirtuin 1; Stilbenes; Tetrazolium Salts; Thiazoles | 2013 |
Structural insights into Aβ42 oligomers using site-directed spin labeling.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Circular Dichroism; Electron Spin Resonance Spectroscopy; HeLa Cells; Humans; Microscopy, Electron, Transmission; PC12 Cells; Peptide Fragments; Protein Folding; Protein Structure, Secondary; Rats; Spin Labels; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2013 |
Protective effect of sulfurous water in peripheral blood mononuclear cells of Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cell Survival; Comet Assay; DNA Damage; Drug Evaluation, Preclinical; Female; Humans; Hydrogen Sulfide; In Vitro Techniques; Leukocytes, Mononuclear; Male; Tetrazolium Salts; Thiazoles; Water | 2015 |
Abeta mediated diminution of MTT reduction--an artefact of single cell culture?
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Brain; Electrophysiology; Hippocampus; Long-Term Potentiation; Male; Microglia; Neurons; Rats; Rats, Wistar; Synapses; Tetrazolium Salts; Thiazoles | 2008 |
nELAV proteins alteration in Alzheimer's disease brain: a novel putative target for amyloid-beta reverberating on AbetaPP processing.
Topics: ADAM Proteins; ADAM10 Protein; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Antigens, Surface; Brain; Case-Control Studies; Cell Cycle; Cell Line, Tumor; Disease Progression; ELAV Proteins; ELAV-Like Protein 1; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Humans; Male; Membrane Proteins; Neuroblastoma; Peptide Fragments; Postmortem Changes; RNA-Binding Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2009 |
Involvement of protein trafficking in deprenyl-induced alpha-secretase activity regulation in PC12 cells.
Topics: ADAM Proteins; ADAM10 Protein; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Brefeldin A; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Neuroprotective Agents; PC12 Cells; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Rats; Selegiline; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Up-regulation of the type 3 ryanodine receptor is neuroprotective in the TgCRND8 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Green Fluorescent Proteins; Humans; Mice; Mice, Transgenic; Mutation; Neurons; Peptide Fragments; Phosphopyruvate Hydratase; Potassium; Presenilin-1; RNA, Messenger; RNA, Small Interfering; Ryanodine Receptor Calcium Release Channel; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Calpain; Coloring Agents; Cyclin-Dependent Kinase 5; Glutamic Acid; Humans; Immunohistochemistry; MAP Kinase Kinase 6; Mice; Mice, Transgenic; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
Abeta20-29 peptide blocking apoE/Abeta interaction reduces full-length Abeta42/40 fibril formation and cytotoxicity in vitro.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Benzothiazoles; Cell Survival; Cells, Cultured; Fluorescent Dyes; Humans; Microscopy, Electron; Neurofibrils; Peptide Fragments; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles | 2010 |
Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Blood Platelets; Brefeldin A; Caspase 3; Cell Death; Cell Fusion; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression Regulation; Heat-Shock Proteins; Humans; Hybrid Cells; In Situ Nick-End Labeling; Male; Middle Aged; Mitochondria; Peptide Fragments; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Tetrazolium Salts; Thapsigargin; Thiazoles | 2012 |
The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Apoptosis; Aspartic Acid Endopeptidases; Blotting, Western; Brain; Cell Death; Coloring Agents; Fluorescent Antibody Technique; Gene Expression Regulation; In Situ Nick-End Labeling; MicroRNAs; Necrosis; PC12 Cells; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection | 2012 |
Promotion of β-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Blotting, Western; C-Reactive Protein; Coloring Agents; Complement C1; Enzyme-Linked Immunosorbent Assay; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Mice, Transgenic; PC12 Cells; Presenilin-1; Presenilin-2; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
A multifunctional peptide rescues memory deficits in Alzheimer's disease transgenic mice by inhibiting Aβ42-induced cytotoxicity and increasing microglial phagocytosis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Cloning, Molecular; Coloring Agents; DNA; Enzyme-Linked Immunosorbent Assay; Humans; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Microglia; Nitric Oxide; Peptide Fragments; Peptide Library; Peptides; Phagocytosis; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Blotting, Western; Cell Line, Tumor; Circular Dichroism; Electron Spin Resonance Spectroscopy; Fluorenes; Fluorescent Antibody Technique; Free Radical Scavengers; Humans; Microscopy, Atomic Force; Models, Biological; Molecular Structure; Nitrogen Oxides; Spin Labels; Tetrazolium Salts; Thiazoles | 2012 |
4-Hydroxyhexenal (HHE) impairs glutamate transport in astrocyte cultures.
Topics: Aged, 80 and over; Aldehydes; Alzheimer Disease; Animals; Astrocytes; Biological Transport, Active; Blotting, Western; Brain Chemistry; Cells, Cultured; Cognitive Dysfunction; Coloring Agents; Excitatory Amino Acid Transporter 2; Female; Glutamate Plasma Membrane Transport Proteins; Glutamates; Humans; Immunoprecipitation; Lipid Peroxidation; Male; Parahippocampal Gyrus; Rats; Tetrazolium Salts; Thiazoles | 2012 |
Toxicity in rat primary neurons through the cellular oxidative stress induced by the turn formation at positions 22 and 23 of Aβ42.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blotting, Western; Cell Survival; Cells, Cultured; Chromans; Congo Red; Female; Free Radical Scavengers; Mutation; Neurons; Neurotoxins; Oxidative Stress; Peptide Fragments; Pregnancy; Protein Conformation; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Vitamin E | 2012 |
A peptide binding to the β-site of APP improves spatial memory and attenuates Aβ burden in Alzheimer's disease transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Benzothiazoles; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Humans; Maze Learning; Memory; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Peptide Library; Peptides; Protein Binding; Protein Structure, Tertiary; Sequence Analysis, DNA; Spatial Behavior; Tetrazolium Salts; Thiazoles | 2012 |
Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid.
Topics: Active Transport, Cell Nucleus; Alzheimer Disease; Amyloid; Animals; Antioxidants; Apoptosis; Astrocytes; Cells, Cultured; DNA; Gene Expression; Humans; L-Lactate Dehydrogenase; Mitochondria; Nerve Tissue Proteins; Neurons; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Synucleins; Tetrazolium Salts; Thiazoles | 2002 |
The effects of the total saponin of Dipsacus asperoides on the damage of cultured neurons induced by beta-amyloid protein 25-35.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Hydro-Lyases; Lipid Peroxidation; Malondialdehyde; Neurons; Neuroprotective Agents; Oleanolic Acid; Oxidative Stress; Peptide Fragments; Rats; Saponins; Tetrazolium Salts; Thiazoles | 2002 |
Neurotoxicity and physicochemical properties of Abeta mutant peptides from cerebral amyloid angiopathy: implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloidosis; Animals; Coloring Agents; Humans; Hydrogen Bonding; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Mutation; PC12 Cells; Peptide Fragments; Peptides; Protein Conformation; Protein Structure, Secondary; Rats; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Flavonoids; Humans; Kidney; Kinetics; Microscopy, Electron; Peptide Fragments; Phenols; Polymers; Quercetin; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles | 2003 |
Oxidative stress impairs glutamate uptake in fibroblasts from patients with Alzheimer's disease.
Topics: Acetylcysteine; Adenosine Triphosphate; Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Animals; Antioxidants; Case-Control Studies; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Fibroblasts; Free Radicals; Glutamic Acid; Glutathione; Humans; L-Lactate Dehydrogenase; Lipid Peroxidation; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Altered transcriptional regulators in response to serum in immortalized lymphocytes from Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Blotting, Western; Case-Control Studies; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Proliferation; Culture Media, Serum-Free; DNA-Binding Proteins; E2F Transcription Factors; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Female; Humans; Imidazoles; Lymphocyte Activation; Lymphocytes; Male; NF-kappa B; Phosphorylation; Serum; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2005 |
Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Catalytic Domain; Cell Line, Tumor; Cell Survival; Coloring Agents; Culture Media; Dopamine; Humans; Immunohistochemistry; Insecta; Kinetics; Male; Matrix Metalloproteinase 3; Matrix Metalloproteinases; Nerve Tissue Proteins; Nitric Oxide; Nitrites; Oxidopamine; Oxygen; Parkinson Disease; Protein Binding; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substantia Nigra; Synucleins; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Deficiency of disulfide bonds facilitating fibrillogenesis of endostatin.
Topics: Alanine; Alzheimer Disease; Animals; Benzothiazoles; Cell Survival; Circular Dichroism; Disulfides; Endostatins; Escherichia coli; Fibril-Associated Collagens; Fluorescent Dyes; Glutathione; Hydrogen-Ion Concentration; Light; Microscopy, Atomic Force; Neovascularization, Pathologic; PC12 Cells; Protein Conformation; Protein Structure, Tertiary; Rats; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tryptophan; Ultraviolet Rays | 2006 |
Increased susceptibility to amyloid toxicity in familial Alzheimer's fibroblasts.
Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Apoptosis; Case-Control Studies; Caspase 3; Cells, Cultured; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Extracellular Fluid; Family Health; Fibroblasts; Humans; Middle Aged; Oxidative Stress; Plaque, Amyloid; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2007 |
Monoclonal antibodies that target pathological assemblies of Abeta.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Antibody Specificity; Brain; Calmodulin-Binding Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Epitopes; Glial Fibrillary Acidic Protein; Humans; Immunoblotting; Immunohistochemistry; Mice; Neurons; Peptide Fragments; Protein Binding; Rabbits; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Influence of Hypericum perforatum extract and its single compounds on amyloid-beta mediated toxicity in microglial cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Cell Membrane; Cell Survival; Humans; Hypericum; L-Lactate Dehydrogenase; Microglia; Models, Chemical; Phagocytosis; Plant Extracts; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Coumarin derivatives protection against ROS production in cellular models of Abeta toxicities.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line, Tumor; Coumarins; Free Radicals; Humans; Hydrogen Peroxide; Mice; Mice, Transgenic; Models, Chemical; Mutation; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Differences between normal and alpha-synuclein overexpressing SH-SY5Y neuroblastoma cells after Abeta(1-42) and NAC treatment.
Topics: alpha-Synuclein; Alzheimer Disease; Amphotericin B; Amyloid; Amyloid beta-Peptides; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Molecular Weight; Neuroblastoma; Peptide Fragments; Ruthenium Red; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
The free radical antioxidant vitamin E protects cortical synaptosomal membranes from amyloid beta-peptide(25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease.
Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biomarkers; Cells, Cultured; Cerebral Cortex; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Neuroprotective Agents; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Sprague-Dawley; Synaptosomes; Tetrazolium Salts; Thiazoles; Vitamin E | 1998 |
Amyloid beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cell Count; Cerebral Cortex; Creatine Kinase; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamate-Ammonia Ligase; Hippocampus; Humans; Mitochondria; Neurons; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Spin Labels; Synaptosomes; Tetrazolium Salts; Thiazoles; Trypan Blue | 1999 |
Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer beta-amyloid fibril formation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Carbazoles; Carvedilol; Cell Survival; Daunorubicin; Humans; Inhibitory Concentration 50; Microscopy, Electron; Models, Chemical; Molecular Structure; Neurons; Polymers; Propanolamines; Protein Binding; Rolitetracycline; Structure-Activity Relationship; Tetrazolium Salts; Thermodynamics; Thiazoles; Tumor Cells, Cultured | 1999 |
Alzheimer's disease presenilin-1 exon 9 deletion and L250S mutations sensitize SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis.
Topics: Alzheimer Disease; Apoptosis; Brain Neoplasms; Cell Movement; Coloring Agents; Gene Deletion; Glucose; Humans; Hypertonic Solutions; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Membrane Proteins; Mutation; Neurites; Neuroblastoma; Osmotic Pressure; Presenilin-1; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 2000 |
Toxicity of non-abeta component of Alzheimer's disease amyloid, and N-terminal fragments thereof, correlates to formation of beta-sheet structure and fibrils.
Topics: alpha-Synuclein; Alzheimer Disease; Amino Acid Sequence; Amyloid; Animals; Cell Survival; Circular Dichroism; Humans; Microscopy, Electron; Molecular Sequence Data; Nerve Tissue Proteins; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Protein Structure, Secondary; Rats; Solubility; Synucleins; Tetrazolium Salts; Thiazoles; Time Factors | 2000 |
Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Apoptosis; Cell Survival; CHO Cells; Chromans; Cricetinae; Dimethyl Sulfoxide; Humans; Hydrogen Peroxide; Neuroblastoma; Oxidative Stress; Peptide Fragments; Phosphatidylserines; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 2000 |
Huperzine A and donepezil protect rat pheochromocytoma cells against oxygen-glucose deprivation.
Topics: Alkaloids; Alzheimer Disease; Animals; Cell Size; Cell Survival; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Glucose; Hypoxia-Ischemia, Brain; Indans; Lipid Peroxidation; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Piperidines; Rats; Sesquiterpenes; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2001 |
Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biological Assay; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Coloring Agents; Dose-Response Relationship, Drug; Drug Interactions; Fetus; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Peptide Fragments; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Thioctic Acid | 2001 |
Melatonin protects SHSY5Y neuroblastoma cells from cobalt-induced oxidative stress, neurotoxicity and increased beta-amyloid secretion.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cobalt; Glutathione; Humans; Melatonin; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
The role of the MAP-kinase superfamily in beta-amyloid toxicity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Blotting, Western; Coloring Agents; Dose-Response Relationship, Drug; Hydrogen Peroxide; In Vitro Techniques; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Reduction of trophic support enhances apoptosis in PC12 cells expressing Alzheimer's APP mutation and sensitizes cells to staurosporine-induced cell death.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apoptosis; Culture Media; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Humans; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Mutation; Neurons; Oxidative Stress; PC12 Cells; Rats; Staurosporine; Tetrazolium Salts; Thiazoles | 2002 |