Compounds > thiazolidines
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thiazolidines and Osteoporosis, Postmenopausal

thiazolidines has been researched along with Osteoporosis, Postmenopausal in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deacon, S; Eastell, R; Hasegawa, C; Hashimoto, Y; Tanaka, M1
Boonen, S; Deacon, S; Eastell, R; Kuwayama, T; Nagase, S; Ohyama, M; Small, M; Spector, T1
Deacon, S; Eastell, R; Engelke, K; Fuerst, T; Genant, HK; Kuwayama, T; Nagase, S; Small, M1
Deacon, S; Hasegawa, C; Ieiri, I; Kastrissios, H; Monteleone, J; Nagase, S; Ogawa, M; Ohno, T; Ohyama, M; Small, M; Umemura, T1
Gamsjäger, M; Resch, H1
Deacon, S; Dijk, DJ; Eastell, R; Greenwood, A; Sharpe, J; Small, M; Tanimoto, M; Yamada, H; Yuba, M1
Boonen, S; Deacon, S; Eastell, R; Kuwayama, T; Nagase, S; Ohyama, M; Sawyer, J; Small, M; Spector, T1
Deacon, S; Hashimoto, Y; Kuwayama, T; Nagase, S; Ohyama, M; Small, M2
Boonen, S; Claessens, F; Papapoulos, S; Rosenberg, E; Vanderschueren, D1

Reviews

2 review(s) available for thiazolidines and Osteoporosis, Postmenopausal

ArticleYear
[Cathepsin K antagonists: preclinical and clinical data].
    Wiener medizinische Wochenschrift (1946), 2015, Volume: 165, Issue:3-4

    Topics: Biphenyl Compounds; Bone Density; Bone Density Conservation Agents; Bone Resorption; Cathepsin K; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Osteoclasts; Osteoporosis, Postmenopausal; Thiazolidines

2015
Inhibition of cathepsin K for treatment of osteoporosis.
    Current osteoporosis reports, 2012, Volume: 10, Issue:1

    Topics: Alkaline Phosphatase; Animals; Biphenyl Compounds; Bone Density; Bone Remodeling; Bone Resorption; Cathepsin K; Humans; Osteoporosis; Osteoporosis, Postmenopausal; Thiazolidines

2012

Trials

8 trial(s) available for thiazolidines and Osteoporosis, Postmenopausal

ArticleYear
Antiresorptive effect of a cathepsin K inhibitor ONO-5334 and its relationship to BMD increase in a phase II trial for postmenopausal osteoporosis.
    BMC musculoskeletal disorders, 2017, Jun-19, Volume: 18, Issue:1

    Topics: Aged; Bone Density; Bone Density Conservation Agents; Cathepsin K; Double-Blind Method; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Thiazolidines; Treatment Outcome

2017
Effect of ONO-5334 on bone mineral density and biochemical markers of bone turnover in postmenopausal osteoporosis: 2-year results from the OCEAN study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, Volume: 29, Issue:2

    Topics: Aged; Alendronate; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Resorption; Cathepsin K; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteogenesis; Osteoporosis, Postmenopausal; Thiazolidines; Time Factors

2014
The effect of the cathepsin K inhibitor ONO-5334 on trabecular and cortical bone in postmenopausal osteoporosis: the OCEAN study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, Volume: 29, Issue:3

    Topics: Absorptiometry, Photon; Aged; Bone Density; Cathepsin K; Double-Blind Method; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Placebos; Thiazolidines; Tomography, X-Ray Computed

2014
Modeling and simulation of bone mineral density response from a phase 2 study of ONO-5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis.
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:8

    Topics: Aged; Bone Density; Bone Density Conservation Agents; Cathepsin K; Computer Simulation; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Models, Biological; Osteoporosis, Postmenopausal; Thiazolidines

2014
Morning vs evening dosing of the cathepsin K inhibitor ONO-5334: effects on bone resorption in postmenopausal women in a randomized, phase 1 trial.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016, Volume: 27, Issue:1

    Topics: Aged; Biomarkers; Bone Density Conservation Agents; Bone Resorption; Cathepsin K; Circadian Clocks; Collagen Type I; Cross-Over Studies; Drug Administration Schedule; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Postmenopause; Single-Blind Method; Thiazolidines

2016
Safety and efficacy of the cathepsin K inhibitor ONO-5334 in postmenopausal osteoporosis: the OCEAN study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, Volume: 26, Issue:6

    Topics: Biomarkers; Bone Density; Bone Remodeling; Cathepsin K; Demography; Enzyme Inhibitors; Female; Humans; Osteoporosis, Postmenopausal; Thiazolidines; Treatment Outcome

2011
Pharmacodynamic effects on biochemical markers of bone turnover and pharmacokinetics of the cathepsin K inhibitor, ONO-5334, in an ascending multiple-dose, phase 1 study.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:3

    Topics: Area Under Curve; Biomarkers; Bone Density; Bone Density Conservation Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Middle Aged; Osteoporosis, Postmenopausal; Thiazolidines

2012
Serum and urine bone resorption markers and pharmacokinetics of the cathepsin K inhibitor ONO-5334 after ascending single doses in post menopausal women.
    British journal of clinical pharmacology, 2012, Volume: 74, Issue:6

    Topics: Administration, Oral; Aged; Area Under Curve; Biomarkers; Bone Resorption; Cathepsin K; Collagen Type I; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Postmenopause; Thiazolidines

2012