Compounds > thiazolidines
Page last updated: 2024-08-21

thiazolidines and Neoplasms

thiazolidines has been researched along with Neoplasms in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199014 (21.88)18.7374
1990's6 (9.38)18.2507
2000's6 (9.38)29.6817
2010's32 (50.00)24.3611
2020's6 (9.38)2.80

Authors

AuthorsStudies
Alkahtani, S; Anwar, J; Arshad, N; Channar, PA; Farooqi, SI; Javaid, M; Javed, A; Mir, MI; Perveen, F; Saeed, A1
Kaminskyy, D; Kryshchyshyn-Dylevych, A; Lesyk, R; Lewińska, A; Skóra, B; Szychowski, KA1
Banjac, NR; Božić, B; Dojčinović, B; Kaluđerović, GN; Pantelić, NĐ; Wessjohann, LA; Zmejkovski, BB1
An, J; Jin, Y; Li, H; Sun, L; Wang, B; Yang, X; Youmei, A; Zhang, H; Zhang, Z; Zhao, J1
Chawla, P; Chawla, V; Faruk, A; Negi, M1
Kaminskyy, D; Khyluk, D; Kryshchyshyn-Dylevych, A; Lesyk, R; Skóra, B; Szychowski, KA1
Bielenica, A; Giliberti, G; Koziol, AE; Madeddu, S; Materek, IB; Olejarz, W; Struga, M; Szulczyk, D1
Clarke, P; de Bono, J; Dolly, SO; Drosopoulos, K; Gurden, MD; Kaye, S; Linardopoulos, S; Workman, P1
Horibe, S; Kawauchi, S; Murakami, Y; Rikitake, Y; Tanahashi, T1
Chung, C; Cooper, D; He, Y; Lin, Y; Liu, Q; Ni, Z; Ong, E; Sarntivijai, S; Schürer, S; Stathias, V; Terryn, R; Xie, J1
Barinkova, J; Cigler, P; Etrych, T; Forstova, J; Konvalinka, J; Kostka, L; Krystufek, R; Neburkova, J; Sacha, P; Sedlak, F; Simon, P; Spanielova, H; Subr, V; Zackova Suchanova, J1
Alias Anand, SA; Bhat, M; Gurubasavaraja Swamy, PM; Kabilan, S; Kalal, BS; Kumar, V; Pai, VR; Poojary, B; Shruthi, N1
Chen, LS; Cortes, J; de Bono, J; Dean, E; DeAngelo, DJ; Gandhi, V; Godin, R; Kantarjian, H; Keating, K; Lorente, D; McEachern, K; Minden, M; Pease, JE; Tamura, K; Uy, GL; Vishwanathan, K1
Chowdhury, A; Habiba, U; Higashino, F; Hossain, E; Jehung, JP; Kitagawa, Y; Kitamura, T; Kuroshima, T; Sano, H; Shindoh, M; Yanagawa-Matsuda, A1
Chen, T; Gong, G; He, H; Hu, Y; Li, J; Qi, B; Wan, X; Xu, X; Yang, Y; Yue, X; Zhang, A; Zhou, G1
de Lima Ferreira, LP; de Melo Rêgo, MJB; de Moraes Gomes, PAT; de Siqueira, LRP; Leite, ACL1
Arner, A; Atzberger, C; Busse, J; Foerster, F; Gegenfurtner, F; Kalinina, OV; Kubisch-Dohmen, R; Moser, C; Müller, R; Pfitzer, L; Smith, R; Timinszky, G; Vollmar, AM; Wagner, E; Zahler, S; Zisis, T1
Deep, A; Majeed, AB; Mani, V; Mishra, RK; Narasimhan, B; Ramasamy, K1
Aw Yong, KM; Getzenberg, RH; Phillip, JM; Vindivich, D; Wirtz, D; Wu, PH; Zeng, Y1
Amin, SG; Choe, KN; Colledge, AL; Desai, DH; Dick, TE; Hengst, JA; Kale, VP; Sung, SS; Takahashi, Y; Yun, JK1
Angrisani, A; Barbato, V; Braun, S; Fiorentino, I; Furia, M; Fusco, S; Gualtieri, R; Guarnieri, D; Mollo, V; Netti, PA; Talevi, R; Turano, M1
Cao, J; Huang, XE; Liu, J; Qian, ZY; Shi, L; Wang, L; Wu, XY; Xu, X1
Byregowda, TR; Girish, YR; Hanumappa, A; Hegde, M; Raghavan, SC; Rangappa, KS; Rao, S; Sharath Kumar, KS; Vetrivel, M1
Ball, LE; DeAngelo, DJ; Hardiman, G; Kraft, AS; Luevano, LA; Minden, MD; Padi, SK; Song, JH; Warfel, NA1
Kraft, AS; Sainz, AG; Song, JH; Warfel, NA1
Astudillo, L; Capobianco, AJ; Da Silva, TG; Han, X; Jin, K; Landgraf, R; Lee, E; Lopes, PE; MacKerell, AD; Neitzel, LR; Oashi, T; Orton, D; Robbins, DJ; VanWye, J; Wang, Z; Weaver, K; Zhu, X1
Kim, DE; Kim, S; Kwon, TK; Lee, J; Park, JW1
de Oliveira Filho, GB; Espírito Santo, RFD; Leite, ACL; Moreira, DRM; Santos, DS; Santos, FED; Soares, MBP; Villarreal, CF1
Schöffski, P1
Güzel, O; Salman, A1
Chen, J; Li, HQ; Liu, PG; Lv, PC; Mao, WJ; Wang, KR; Xiong, J; Yang, Y; Zhou, CF; Zhu, HL1
Badria, FA; Dawood, KM; Hegazi, B; Mohamed, HA1
Beck-Nielsen, H; Home, PD; Jones, NP; Kahn, SE; Noronha, D; Viberti, G1
Barrett, CM; Coss, CC; Dalton, JT; Hurh, E; Li, CM; Lu, Y; Miller, DD; Narayanan, R1
Choi, H; Fiorilla, C; Gerwick, WH; Malloy, KL; Matainaho, T; Valeriote, FA1
Bise, R; Huh, SI; Kanade, T; Yin, Z1
Cetin-Atalay, R; Durmaz, I; Herscovici, J; Onen-Bayram, FE; Scherman, D1
Panda, D; Rai, A; Surolia, A1
Chen, S; Halfmann, R; Harran, P; Holmes, DL; Lei, X; Li, L; Naidoo, J; Wang, G; Wang, L; Wang, X; Wei, S; Williams, N; Yu, H1
Devinyak, O; Lesyk, R; Zimenkovsky, B1
HARUNA, H; HASHIMOTO, S; IZUMI, K; KATAYAMA, M; MATSUBAYASHI, Y; OGISO, A; OKUJIMA, J; SUZUKI, S; TAKANO, T1
Dennis, JW; Goetz, JG; Guay, G; Joshi, B; Lagana, A; Lajoie, P; Nabi, IR; Partridge, EA; Pawling, J1
Ananda Kumar, CS; Benaka Prasad, SB; Chandrappa, S; Rangappa, KS; Thimmegowda, NR; Vinaya, K1
Brugarolas, A; Gosalvez, M2
Gosálvez, M2
McCarty, MF1
Grier, RL; Merkley, DF; Roth, JA1
Blanco, MF; de Paz, E; Gosálvez, M1
Hahn, FE1
Young, CW1
Lankelma, J; Leyva, A; Penders, PG; Pinedo, HM1
Benetti, GP; Bombelli, G; Fugazza, L; Illeni, MT; La Vecchia, G; Montalto, F; Stramba Badiale, M; Uslenghi, C1
Aosasa, S; Kinoshita, M; Mochizuki, H; Oda, Y; Ohe, H; Ohkusa, Y; Ono, S; Tamakuma, S1
Auteri, A; Bova, G; Bruni, F; Chiarion, C; Di Renzo, M; Ferrì, P; Girardello, R; Pasqui, AL; Saletti, M1
Ali-Osman, F; Srivenugopal, KS1
Alpert, LC; Batist, G; Chen, X; Griffith, OW; Hayward, MA; Schecter, RL1
Batist, G; Carystinos, GD; Chen, X1
Gosálvez Gosálvez, M1
Alonso-Varona, A; Bilbao, J; Bilbao, P; Castro, B; del Olmo, M; Palomares, T1
DeGraff, W; Friedman, N; Mitchell, JB; Russo, A1
Tannenbaum, SR1

Reviews

7 review(s) available for thiazolidines and Neoplasms

ArticleYear
The Role of 4-Thiazolidinone Scaffold in Targeting Variable Biomarkers and Pathways Involving Cancer.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:8

    Topics: Antineoplastic Agents; Biomarkers; Humans; Neoplasms; Thiazolidines

2022
Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Disease Progression; Drug Delivery Systems; Drug Discovery; Humans; Intracellular Signaling Peptides and Proteins; Neoplasms; Thiazoles; Thiazolidines; Thiosemicarbazones

2019
Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology.
    The oncologist, 2009, Volume: 14, Issue:6

    Topics: Aniline Compounds; Animals; Cell Cycle Proteins; Clinical Trials as Topic; Cyclic N-Oxides; Drug Evaluation, Preclinical; Glycine; Humans; Neoplasms; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Pyridines; Sulfonamides; Sulfones; Thiazolidines

2009
Biologically active 4-thiazolidinones: a review of QSAR studies and QSAR modeling of antitumor activity.
    Current topics in medicinal chemistry, 2012, Volume: 12, Issue:24

    Topics: Algorithms; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Humans; Linear Models; Neoplasms; Normal Distribution; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Thiazolidines

2012
Cytostatic and reverse-transforming therapies of cancer - a brief review and future prospects.
    Medical hypotheses, 1982, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents; Benzaldehydes; Cell Transformation, Neoplastic; Cyclic AMP; Growth Inhibitors; Humans; Interferons; Neoplasms; Protease Inhibitors; Solvents; Thiazoles; Thiazolidines; Vitamin A

1982
Potential for selective modulation of glutathione in cancer chemotherapy.
    Chemico-biological interactions, 1998, Apr-24, Volume: 111-112

    Topics: Animals; Buthionine Sulfoximine; Cell Communication; Drug Resistance; Enzyme Inhibitors; Female; Gap Junctions; Glutamate-Cysteine Ligase; Glutathione; Humans; Mammary Neoplasms, Experimental; Neoplasms; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines

1998
Diet and exposure to N-nitroso compounds.
    Princess Takamatsu symposia, 1985, Volume: 16

    Topics: Bacteria; Diet; Food; Humans; Neoplasms; Nitrates; Nitrites; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines

1985

Trials

7 trial(s) available for thiazolidines and Neoplasms

ArticleYear
Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers.
    British journal of cancer, 2018, Volume: 118, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Biphenyl Compounds; Cytochrome P-450 CYP3A; Female; Gene Expression Regulation, Neoplastic; Hematologic Neoplasms; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Protein Kinase Inhibitors; Thiazolidines; Up-Regulation; Young Adult

2018
Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials.
    Diabetologia, 2010, Volume: 53, Issue:9

    Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Neoplasms; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Thiazolidines; Treatment Outcome

2010
Reversal of cancer.
    Lancet (London, England), 1983, Apr-09, Volume: 1, Issue:8328

    Topics: Antineoplastic Agents; Bucladesine; Cell Differentiation; Clinical Trials as Topic; Humans; Neoplasms; Thiazoles; Thiazolidines

1983
Thiazolidine-4-carboxylic acid, a selective drug against human cancers.
    Die Naturwissenschaften, 1980, Volume: 67, Issue:6

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Lethal Dose 50; Male; Mice; Neoplasms; Neoplasms, Experimental; Thiazoles; Thiazolidines

1980
Preliminary clinical results with norgamem (thioproline) and revercan (2-amino-2-thiazoline): the first inducers of reverse transformation.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1982, Volume: 80

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Clinical Trials as Topic; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasms; Thiazoles; Thiazolidines; Urinary Bladder Neoplasms

1982
Lessons of the laetrile study.
    Clinical bulletin, 1981, Volume: 11, Issue:3

    Topics: Amygdalin; Attitude; Benzaldehydes; Clinical Trials as Topic; Complementary Therapies; Humans; Neoplasms; Philosophy; Politics; Quackery; Research Design; Thiazoles; Thiazolidines; United States

1981
Ex vivo evaluation of pidotimod activity on cell-mediated immunity.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:12A

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; CD3 Complex; Double-Blind Method; Female; Humans; Immunity, Cellular; Lymphocyte Count; Male; Middle Aged; Neoplasms; Phytohemagglutinins; Pyrrolidonecarboxylic Acid; Stimulation, Chemical; T-Lymphocytes; Thiazoles; Thiazolidines

1994

Other Studies

50 other study(ies) available for thiazolidines and Neoplasms

ArticleYear
Investigations on Anticancer Potentials by DNA Binding and Cytotoxicity Studies for Newly Synthesized and Characterized Imidazolidine and Thiazolidine-Based Isatin Derivatives.
    Molecules (Basel, Switzerland), 2022, Jan-06, Volume: 27, Issue:2

    Topics: Antineoplastic Agents; Cell Proliferation; DNA; HeLa Cells; Humans; Imidazolidines; Isatin; MCF-7 Cells; Molecular Structure; Neoplasms; Structure-Activity Relationship; Thiazolidines

2022
Evaluation of Anticancer and Antibacterial Activity of Four 4-Thiazolidinone-Based Derivatives.
    Molecules (Basel, Switzerland), 2022, Jan-28, Volume: 27, Issue:3

    Topics: A549 Cells; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Line, Tumor; Humans; Neoplasms; Pseudomonas aeruginosa; Pseudomonas Infections; Thiazolidines

2022
Synthesis, characterization and in vitro biological evaluation of novel organotin(IV) compounds with derivatives of 2-(5-arylidene-2,4-dioxothiazolidin-3-yl)propanoic acid.
    Journal of inorganic biochemistry, 2020, Volume: 211

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Neoplasms; Nitric Oxide; Organotin Compounds; Propionates; Spectroscopy, Fourier Transform Infrared; Thiazolidines

2020
Limiting tumor cells comprehensively at micro and macro levels to improve the therapeutic effect of chemotherapy.
    Nanotechnology, 2021, Jan-01, Volume: 32, Issue:1

    Topics: Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Movement; Cell Proliferation; Doxorubicin; Drug Synergism; Humans; Liposomes; Mice, Nude; Neoplasms; Thiazolidines

2021
4-thiazolidinone-based derivatives rosiglitazone and pioglitazone affect the expression of antioxidant enzymes in different human cell lines.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 139

    Topics: A549 Cells; Antioxidants; Apoptosis; Caco-2 Cells; Caspase 3; Cell Line; Cell Line, Tumor; Humans; Neoplasms; Oxidative Stress; Pioglitazone; PPAR gamma; Reactive Oxygen Species; Rosiglitazone; Thiazolidines

2021
1H-Tetrazol-5-amine and 1,3-thiazolidin-4-one derivatives containing 3-(trifluoromethyl)phenyl scaffold: Synthesis, cytotoxic and anti-HIV studies.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 94

    Topics: Amines; Anti-HIV Agents; Antineoplastic Agents; Cell Line, Tumor; Cells, Cultured; Crystallography, X-Ray; HIV Infections; Humans; Neoplasms; Structure-Activity Relationship; Tetrazoles; Thiazolidines

2017
RNAi screen reveals synthetic lethality between cyclin G-associated kinase and FBXW7 by inducing aberrant mitoses.
    British journal of cancer, 2017, Sep-26, Volume: 117, Issue:7

    Topics: Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Clathrin; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Humans; Intracellular Signaling Peptides and Proteins; Mitosis; Neoplasms; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Sulfonamides; Synthetic Lethal Mutations; Thiazolidines; Ubiquitin-Protein Ligases

2017
Mechanism of recipient cell-dependent differences in exosome uptake.
    BMC cancer, 2018, 01-06, Volume: 18, Issue:1

    Topics: A549 Cells; Biological Transport; Endocytosis; Exosomes; Genistein; HCT116 Cells; Humans; Neoplasm Metastasis; Neoplasms; Sulfonamides; Thiazolidines

2018
Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses.
    BMC bioinformatics, 2017, 12-21, Volume: 18, Issue:Suppl 17

    Topics: Apoptosis; Breast; Cell Line; Cells, Cultured; Computational Biology; Female; Gene Expression Profiling; Gene Expression Regulation; High-Throughput Screening Assays; Humans; Macrolides; Neoplasms; Thiazolidines

2017
Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.
    Molecular pharmaceutics, 2018, 08-06, Volume: 15, Issue:8

    Topics: Antigens, Surface; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Click Chemistry; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Nanoconjugates; Neoplasms; Recombinant Proteins; Thiazolidines

2018
Synthesis and evaluation of thiazolidinone-pyrazole conjugates as anticancer and antimicrobial agents.
    Future medicinal chemistry, 2018, 05-01, Volume: 10, Issue:9

    Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Candida albicans; Candidiasis; Cell Line, Tumor; Cell Survival; Humans; Mice; Molecular Docking Simulation; Neoplasms; Proto-Oncogene Proteins c-mdm2; Pyrazoles; Structure-Activity Relationship; Thiazolidines

2018
HuR translocation to the cytoplasm of cancer cells in actin-independent manner.
    Experimental cell research, 2018, 08-15, Volume: 369, Issue:2

    Topics: 3' Untranslated Regions; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cytoplasm; Cytoskeleton; ELAV-Like Protein 1; HeLa Cells; Hep G2 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Myosins; Neoplasms; Protein Binding; Protein Transport; RNA Stability; RNA, Messenger; Thiazolidines

2018
Discovery of N
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Apoptosis; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-met; Thiazolidines; Urea

2019
Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.
    Cell death & disease, 2019, 04-03, Volume: 10, Issue:4

    Topics: Actins; Animals; Antineoplastic Combined Chemotherapy Protocols; Bacterial Proteins; Bridged Bicyclo Compounds, Heterocyclic; Cell Death; Depsipeptides; DNA Damage; DNA End-Joining Repair; DNA Repair; DNA-Activated Protein Kinase; Doxorubicin; HeLa Cells; Humans; Ku Autoantigen; Mice; Mice, Inbred BALB C; Mice, SCID; Neoplasms; Phosphorylation; Recombination, Genetic; Replication Protein A; Thiazolidines; Transplantation, Heterologous

2019
Synthesis, antimicrobial, anticancer evaluation and QSAR studies of thiazolidin-4-ones clubbed with quinazolinone.
    Current topics in medicinal chemistry, 2013, Volume: 13, Issue:16

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Drug Screening Assays, Antitumor; Fungi; HCT116 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Neoplasms; Quantitative Structure-Activity Relationship; Quinazolinones; Thiazolidines

2013
Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis.
    Journal of cellular physiology, 2014, Volume: 229, Issue:3

    Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Shape; Depsipeptides; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; HCT116 Cells; Humans; Mice, Nude; Neoplasm Metastasis; Neoplasms; Neoplastic Cells, Circulating; RNA, Messenger; Thiazolidines; Time Factors; Tumor Microenvironment; Up-Regulation

2014
A novel selective multikinase inhibitor of ROCK and MRCK effectively blocks cancer cell migration and invasion.
    Cancer letters, 2014, Nov-28, Volume: 354, Issue:2

    Topics: Cell Line, Tumor; Cell Movement; Humans; Myotonin-Protein Kinase; Neoplasm Invasiveness; Neoplasms; Protein Kinase Inhibitors; rho-Associated Kinases; Thiazolidines

2014
Energy independent uptake and release of polystyrene nanoparticles in primary mammalian cell cultures.
    Experimental cell research, 2015, Jan-15, Volume: 330, Issue:2

    Topics: Amiloride; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Caveolin 1; Cell Membrane; Cells, Cultured; Colon; Drug Delivery Systems; Endocytosis; Epithelial Cells; Female; Fibroblasts; Humans; Hydrazones; Microscopy, Confocal; Nanoparticles; Neoplasms; Oviducts; Particle Size; Polystyrenes; Primary Cell Culture; Spectrometry, Fluorescence; Sucrose; Thiazolidines

2015
Leucogen tablets at 60 mg three times per day are safe and effective to control febrile neutropenia.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:19

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Prognosis; Prospective Studies; Safety; Tablets; Thiazolidines

2014
Antiproliferative and tumor inhibitory studies of 2,3 disubstituted 4-thiazolidinone derivatives.
    Bioorganic & medicinal chemistry letters, 2015, Sep-01, Volume: 25, Issue:17

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Leukemia; Mice; Neoplasms; Structure-Activity Relationship; Thiazolidines

2015
Insulin receptor substrate 1 is a substrate of the Pim protein kinases.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Biphenyl Compounds; Cell Proliferation; Clinical Trials, Phase I as Topic; Humans; Insulin Receptor Substrate Proteins; Leukemia, Experimental; Leukemia, T-Cell; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Staging; Neoplasms; Phosphorylation; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Signal Transduction; Thiazolidines; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:7

    Topics: Animals; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Models, Biological; Neoplasms; NF-E2-Related Factor 2; Prostatic Neoplasms; Protein Binding; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins c-pim-1; Reactive Oxygen Species; Signal Transduction; Thiazolidines; Xenograft Model Antitumor Assays

2016
The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis.
    Cancer research, 2016, 06-15, Volume: 76, Issue:12

    Topics: Animals; Cell Line, Tumor; DNA-Binding Proteins; Humans; Mice; Neoplasms; Receptors, Notch; Somites; Thiazolidines; Transcription Factors; Transcriptional Activation; Zebrafish

2016
The multi-target drug BAI induces apoptosis in various human cancer cells through modulation of Bcl-xL protein.
    International journal of oncology, 2016, Volume: 49, Issue:6

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Down-Regulation; HCT116 Cells; Humans; Indazoles; Membrane Potential, Mitochondrial; Neoplasms; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Thiazolidines; Tumor Suppressor Protein p53

2016
Structural improvement of new thiazolidinones compounds with antinociceptive activity in experimental chemotherapy-induced painful neuropathy.
    Chemical biology & drug design, 2017, Volume: 90, Issue:2

    Topics: Analgesics; Animals; Antineoplastic Agents; Male; Mice; Mice, Inbred C57BL; Neoplasms; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Measurement; Peripheral Nervous System Diseases; Thiazolidines

2017
Synthesis and biological evaluation of new 4-thiazolidinone derivatives.
    Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:4

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Female; Humans; Male; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Neoplasms; Thiazolidines

2009
Design, synthesis and biological evaluation of thiazolidinone derivatives as potential EGFR and HER-2 kinase inhibitors.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Models, Molecular; Neoplasms; Protein Binding; Protein Kinase Inhibitors; Receptor, ErbB-2; Structure-Activity Relationship; Thiazolidines

2010
Cytotoxicity and utility of 1-indanone in the synthesis of some new heterocycles.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:4

    Topics: Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Survival; Heterocyclic Compounds; Humans; Hydrazones; Indans; Neoplasms; Thiazoles; Thiazolidines; Triazines

2010
2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.
    International journal of oncology, 2010, Volume: 37, Issue:4

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amides; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Blood Glucose; Carboxylic Acids; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Inhibitory Concentration 50; Injections, Intravenous; Male; Mice; Mice, Inbred ICR; Mice, Nude; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiazolidines; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2010
Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Cyanobacteria; Depsipeptides; Drug Design; Humans; Inhibitory Concentration 50; Isoleucine; Magnetic Resonance Spectroscopy; Models, Chemical; Neoplasms; Proto-Oncogene Proteins c-mdm2; Ribosomes; Thiazoles; Thiazolidines; Tumor Suppressor Protein p53

2012
Automatic cell tracking applied to analysis of cell migration in wound healing assay.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2011, Volume: 2011

    Topics: Algorithms; Animals; Automation; Bridged Bicyclo Compounds, Heterocyclic; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cell Tracking; Cells, Cultured; Culture Media; Equipment Design; Humans; Imaging, Three-Dimensional; Microscopy; Microscopy, Phase-Contrast; Mitosis; Neoplasms; Thiazolidines; Time Factors; Wound Healing

2011
A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells.
    Bioorganic & medicinal chemistry, 2012, Sep-01, Volume: 20, Issue:17

    Topics: Antineoplastic Agents; Apoptosis; Caspase 9; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Neoplasms; Structure-Activity Relationship; Thiazolidines

2012
An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Calcium-Binding Proteins; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Drug Screening Assays, Antitumor; Humans; Kinetochores; Mad2 Proteins; Mice; Microtubules; Mitotic Index; Neoplasms; Polymerization; Porphobilinogen; Protein Serine-Threonine Kinases; Repressor Proteins; Rhodanine; Thiazolidines; Thiones; Tubulin; Tubulin Modulators; Tumor Suppressor Protein p53; Vinblastine

2012
Small-molecule activation of the TRAIL receptor DR5 in human cancer cells.
    Nature chemical biology, 2013, Volume: 9, Issue:2

    Topics: Apoptosis; Caspase 3; Caspase 8; Caspases; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Kinetics; Models, Chemical; Neoplasms; Phthalimides; Protein Binding; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Proteins; RNA, Small Interfering; Thiazolidines; TNF-Related Apoptosis-Inducing Ligand

2013
[THE EFFECT OF LEYK (CYSTEINE DERIVATIVE) ON THE RADIATION INJURY].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1963, Volume: 23

    Topics: Anemia; Animals; Blood Cell Count; Cysteine; Neoplasms; Pharmacology; Rabbits; Radiation Injuries; Radiation-Protective Agents; Research; Thiazolidines

1963
Plasma membrane domain organization regulates EGFR signaling in tumor cells.
    The Journal of cell biology, 2007, Oct-22, Volume: 179, Issue:2

    Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Caveolin 1; Cell Membrane; Cytoskeleton; Diffusion; Embryonic Stem Cells; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Fluorescence Recovery After Photobleaching; Galectins; Mice; Models, Biological; Neoplasms; Nerve Tissue Proteins; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Signal Transduction; Thiazolidines

2007
Synthesis and in vitro antiproliferative activity against human cancer cell lines of novel 5-(4-methyl-benzylidene)-thiazolidine-2,4-diones.
    Investigational new drugs, 2008, Volume: 26, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Thiazolidines

2008
Treatment of cancer by an inducer of reverse transformation.
    Lancet (London, England), 1980, Jan-12, Volume: 1, Issue:8159

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carboxylic Acids; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Neoplasms; Thiazoles; Thiazolidines

1980
Thioproline.
    Lancet (London, England), 1980, Mar-15, Volume: 1, Issue:8168 Pt 1

    Topics: Administration, Oral; Child; Humans; Injections, Intravenous; Neoplasms; Thiazoles; Thiazolidines

1980
Thioproline and reversal of cancer.
    Lancet (London, England), 1983, May-14, Volume: 1, Issue:8333

    Topics: Antineoplastic Agents; Humans; Neoplasms; Thiazoles; Thiazolidines

1983
Pilot study on the treatment with thioproline of 24 small animals with tumors.
    American journal of veterinary research, 1984, Volume: 45, Issue:10

    Topics: Animals; Antineoplastic Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Injections, Subcutaneous; Male; Neoplasms; Pilot Projects; Thiazoles; Thiazolidines

1984
[Transrecters. A new group of inducers of reverse transformation with possible use in the treatment of human cancer].
    Revista espanola de oncologia, 1982, Volume: 29, Issue:4

    Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; HeLa Cells; Humans; Neoplasms; Thiazoles; Thiazolidines

1982
Determination of thioproline in plasma using high performance liquid chromatography.
    Cancer letters, 1981, Volume: 12, Issue:1-2

    Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Humans; Neoplasms; Thiazoles; Thiazolidines

1981
Clinical and experimental studies on the role of platelet-activating factor (PAF) in the pathogenesis of septic DIC.
    Surgery today, 1993, Volume: 23, Issue:3

    Topics: Aged; Animals; Blood Pressure; Disseminated Intravascular Coagulation; Female; Fibrinolysis; Guanidines; Humans; Male; Middle Aged; Neoplasms; Platelet Activating Factor; Platelet Count; Postoperative Complications; Rabbits; Serine Proteinase Inhibitors; Shock, Septic; Thiazoles; Thiazolidines

1993
The in vitro effect of Pidotimod on some immune functions in cancer patients.
    Immunopharmacology and immunotoxicology, 1997, Volume: 19, Issue:1

    Topics: Adjuvants, Immunologic; Female; Humans; Immunity, Cellular; Immunologic Factors; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1997
Activity and distribution of the cysteine prodrug activating enzyme, 5-oxo-L-prolinase, in human normal and tumor tissues.
    Cancer letters, 1997, Jul-15, Volume: 117, Issue:1

    Topics: Cysteine; Humans; Neoplasms; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1997
Characterization of 5-oxo-L-prolinase in normal and tumor tissues of humans and rats: a potential new target for biochemical modulation of glutathione.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:1

    Topics: Animals; Female; Glutathione; Humans; Immunohistochemistry; Neoplasms; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines

1998
[Reversion of cancer and mitochondrial filamentation].
    Anales de la Real Academia Nacional de Medicina, 2000, Volume: 117, Issue:4

    Topics: Animals; Antineoplastic Agents; Doxorubicin; Drug Screening Assays, Antitumor; Mitochondria; Neoplasms; Rotenone; Thiazoles; Thiazolidines; Uncoupling Agents

2000
L-2-Oxothiazolidine-4-carboxylate reverses the tumour growth-promoting effect of interleukin-2 and improves the anti-tumour efficacy of biochemotherapy in mice bearing B16 melanoma liver metastases.
    Melanoma research, 2002, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Female; Glutathione; Interleukin-2; Liver; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors; Tumor Cells, Cultured

2002
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cisplatin; Glutathione; Humans; Lung; Lung Neoplasms; Melphalan; Methionine Sulfoximine; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin

1986