thiazolidines has been researched along with Leukemia, Myeloid, Acute in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, Y; Chen, H; Chen, Y; Dakin, LA; Deangelo, DJ; Dillman, KS; Gibbons, FD; Grondine, MR; Huszar, D; Kaur, S; Keeton, EK; Lamb, ML; Lyne, PD; McEachern, K; Palakurthi, S; Platanias, LC; Shen, M; Stone, RM; Wang, S; Wu, A; Zheng, X | 1 |
| Arslan, D; Benito, J; Fujimura, T; Harada, M; Jacamo, R; Kaur, S; Kazuno, S; Kojima, K; Konopleva, M; Matsushita, H; Platanias, L; Ramirez, S; Tabe, Y; Yamamoto, S | 1 |
| Chen, LS; Cortes, JE; Gandhi, V; Liang, H; Yang, JY | 1 |
| Casas-Selves, M; Chen, H; Dillman, KS; Gale, RE; Huszar, D; Keeton, EK; Khwaja, A; Lai, Z; Linch, DC; Stengel, C; Tron, AE; Ye, M; Zinda, M | 1 |
| Baer, MR; Doshi, KA; Huszar, D; Natarajan, K; Perrotti, D; Rassool, FV; Tron, AE; Trotta, R | 1 |
| Alexander, P; Dobbie, D; Forbes, P; Powles, R | 1 |
6 other study(ies) available for thiazolidines and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia.
Topics: Animals; Apoptosis; Biphenyl Compounds; Blotting, Western; Cell Cycle; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukemia, Myeloid, Acute; Mice; Mice, SCID; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Thiazolidines; Tissue Distribution; Tumor Cells, Cultured | 2014 |
The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression.
Topics: Apoptosis; Benzamides; Biphenyl Compounds; Blotting, Western; Cell Proliferation; DNA-Binding Proteins; Drug Therapy, Combination; Flow Cytometry; Heat Shock Transcription Factors; Humans; Leukemia, Myeloid, Acute; Morpholines; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Pyrimidines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazolidines; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Cells, Cultured | 2015 |
Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia.
Topics: Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors; Proteome; Proteomics; Proto-Oncogene Proteins c-pim-1; Signal Transduction; Thiazolidines; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2016 |
Next-generation sequencing identifies a novel ELAVL1-TYK2 fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208.
Topics: Biphenyl Compounds; Cell Line, Tumor; Drug Resistance, Neoplasm; ELAV-Like Protein 1; Gene Expression Regulation, Leukemic; High-Throughput Nucleotide Sequencing; Humans; Leukemia, Myeloid, Acute; Oncogene Proteins, Fusion; Protein Kinase Inhibitors; Thiazolidines; TYK2 Kinase | 2016 |
Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds; Cytarabine; DNA Damage; Drug Synergism; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Oxidative Stress; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Reactive Oxygen Species; Signal Transduction; Thiazolidines; Topoisomerase II Inhibitors | 2016 |
Maturation of human peripheral blood leukemic cells in short-term culture.
Topics: Cell Count; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Neutrophils; Prostaglandins A; Thiazoles; Thiazolidines; Time Factors | 1981 |