thiazolidines has been researched along with Diabetes Mellitus in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 13 (44.83) | 29.6817 |
| 2010's | 6 (20.69) | 24.3611 |
| 2020's | 5 (17.24) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, K | 1 |
| Jan, MS; Khan, S; Rashid, U; Sadiq, A; Shah, M | 1 |
| Augsornworawat, P; Hogrebe, NJ; Maxwell, KG; Millman, JR; Velazco-Cruz, L | 1 |
| Andou, S; Hase, M; Ishizawa, F; Kishikawa, Y; Ojima, F; Sakurai, J; Satoh, J; Satoh, S; Takahashi, T | 1 |
| Gyémánt, G; Maccari, R; Ottanà, R; Szabó, K | 1 |
| Homma, K; Homma, Y; Igarashi, M; Matsuoka, T; Ozawa, H; Sasaki, J; Shiina, Y; Yoshizawa, J; Yoshizawa, M | 1 |
| Demitsu, T; Izumi, K; Kakurai, M; Kawase, M; Maki, N; Nishie, W; Shimizu, H; Takazawa, M; Umemoto, N; Yamada, T | 1 |
| Ébert, A; Flodström-Tullberg, M; Harkin, S; Hasib, A; Irwin, N; Kelly, C; Kelsey, R; Khan, D; Maheshwari, RR; Manderson Koivula, FN; McClenaghan, NH; Shaw, JA; Stone, VM; Venglovecz, V; Watson, A; White, MG | 1 |
| Ahn, JH; Cha, BS; Choi, CS; Kang, ES; Kim, YW; Lee, BW; Lee, EY; Lee, HC; Oh, H | 1 |
| Anbazhagan, S; Murugan, R; Sriman Narayanan, S | 1 |
| Betancort, JM; Campbell, DA; Carney, D; Chen, SH; Gordon, E; Hanway, D; Li, X; Liao, W; Liu, J; Liu, R; Schmeits, J; Winn, DT; Xu, Q | 1 |
| Yokoi, H | 1 |
| Okazaki, R | 1 |
| Fujishima, H; Tsubota, K | 1 |
| Demuth, HU; McIntosh, CH; Pederson, RA; Pospisilik, JA; Stafford, SG | 1 |
| Kawakami, M; Kuroki, M | 1 |
| Drozak, J; Winiarska, K | 1 |
| Fujita, H; Hirose, H; Kawai, T; Miyashita, K; Ogawa, T; Saruta, T; Seto, Y; Ukeda, K; Yajima, K; Yamada, T; Yamamoto, Y | 1 |
| Izuhara, Y; Miyata, T; Yamamoto, M | 1 |
| Baba, M; Kimura, K; Suda, T; Yagihashi, S | 1 |
| Akanuma, Y; Hotta, N; Kawamori, R; Matsuoka, K; Oka, Y; Sakamoto, N; Shichiri, M; Shigeta, Y; Toyota, T | 1 |
| Fujishima, H; Shimazaki, J; Tsubota, K; Yagi, Y | 1 |
| Ohta, M | 1 |
| Ide, T; Mochizuki, T; Murakami, K; Nakazawa, T | 1 |
| Aoki, T; Makino, M; Mizuno, K; Sassa, H; Sobajima, H; Suzuki, T; Taniko, K | 1 |
| Yamanouchi, T | 1 |
| Awaya, S; Fukasawa, H; Hotta, N; Kakuta, H; Koh, N; Sakamoto, N; Yasuma, T | 1 |
| Collier, A; Small, M | 1 |
| Kador, PF; Kinoshita, JH; Sharpless, NE | 1 |
8 review(s) available for thiazolidines and Diabetes Mellitus
| Article | Year |
|---|---|
[Elucidation and Application of Novel Action of Therapeutic Agents for Diabetic Neuropathy].
Topics: Aldehyde Reductase; Antioxidants; Cadmium; Chelating Agents; Diabetes Mellitus; Diabetic Neuropathies; Endothelial Cells; Environmental Pollutants; Glutathione; Humans; Ligases; Metallothionein; NF-E2-Related Factor 2; Reactive Oxygen Species; Rhodanine; Thiazolidines | 2022 |
[Thiazolidine].
Topics: Acute Coronary Syndrome; Diabetes Mellitus; Humans; Metabolic Syndrome; Thiazolidines | 2010 |
[Diabetes Mellitus and bone metabolism].
Topics: Bone and Bones; Diabetes Complications; Diabetes Mellitus; Diphosphonates; Fractures, Bone; Glycation End Products, Advanced; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Osteoporosis; Risk; Thiazolidines | 2011 |
[Aminoguanidine and other AGE inhibitors].
Topics: Amides; Animals; Arteriosclerosis; Cardiovascular Diseases; Cataract; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Retinopathy; Disease Models, Animal; Drug Design; Glycation End Products, Advanced; Guanidines; Humans; Hydrazines; Hypoglycemic Agents; Thiadiazoles; Thiazoles; Thiazolidines | 2002 |
[Glutathione in therapy].
Topics: Animals; Cysteine; Diabetes Mellitus; Glutathione; Humans; Infections; Neurodegenerative Diseases; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 2002 |
[Current advances in the treatment of diabetes mellitus].
Topics: Aldehyde Reductase; Arteriosclerosis; Blood Glucose; Diabetes Mellitus; Enzyme Inhibitors; Guanidines; Humans; Hypoglycemic Agents; Insulin Resistance; Rhodanine; Thiazolidines | 1999 |
[KRP-297, MCC-555].
Topics: Animals; Clinical Trials, Phase II as Topic; Diabetes Mellitus; Glucose; Humans; Hypoglycemic Agents; Lipid Metabolism; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors | 2001 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution | 1985 |
5 trial(s) available for thiazolidines and Diabetes Mellitus
| Article | Year |
|---|---|
A Dipeptidyl Peptidase-4 Inhibitor, Teneligliptin, Decreases Plasma Triglyceride-Rich Lipoprotein Remnants in Diabetic Patients with Chronic Kidney Disease Undergoing Hemodialysis.
Topics: Aged; Blood Glucose; Cholesterol; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipids; Lipoproteins; Male; Middle Aged; Pyrazoles; Renal Dialysis; Renal Insufficiency, Chronic; Thiazolidines; Triglycerides | 2017 |
Improvement of corneal fluorescein staining in post cataract surgery of diabetic patients by an oral aldose reductase inhibitor, ONO-2235.
Topics: Administration, Oral; Aged; Aldehyde Reductase; Cataract Extraction; Conjunctiva; Diabetes Mellitus; Double-Blind Method; Enzyme Inhibitors; Epithelium, Corneal; Female; Fluorescein; Fluorescent Dyes; Humans; Male; Microscopy, Fluorescence; Postoperative Period; Rhodanine; Rose Bengal; Sensation; Tears; Thiazolidines | 2002 |
Three-year inhibition of aldose reductase on development of symptomatic neuropathy in diabetic patients.
Topics: Action Potentials; Aldehyde Reductase; Diabetes Mellitus; Diabetic Neuropathies; Double-Blind Method; Electric Stimulation; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neural Conduction; Reaction Time; Rhodanine; Thiazolidines | 2006 |
A long-term effect of epalrestat on motor conduction velocity of diabetic patients: ARI-Diabetes Complications Trial (ADCT).
Topics: Age of Onset; Aged; Aldehyde Reductase; Body Mass Index; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enzyme Inhibitors; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Motor Neurons; Neural Conduction; Prospective Studies; Rhodanine; Thiazolidines | 2007 |
Improvement of corneal sensation and tear dynamics in diabetic patients by oral aldose reductase inhibitor, ONO-2235: a preliminary study.
Topics: Administration, Oral; Aged; Aldehyde Reductase; Cornea; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Rhodanine; Sensation; Tears; Thiazolidines | 1996 |
16 other study(ies) available for thiazolidines and Diabetes Mellitus
| Article | Year |
|---|---|
SAR and lead optimization of (Z)-5-(4-hydroxy-3-methoxybenzylidene)-3-(2-morpholinoacetyl)thiazolidine-2,4-dione as a potential multi-target antidiabetic agent.
Topics: Animals; Diabetes Mellitus; Hypoglycemic Agents; Molecular Docking Simulation; Rats; Thiazolidinediones; Thiazolidines | 2023 |
Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells.
Topics: Actins; Animals; Basic Helix-Loop-Helix Transcription Factors; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cell Engineering; Cell Lineage; Cell- and Tissue-Based Therapy; Cells, Cultured; Cytoskeleton; Diabetes Mellitus; Endoderm; Homeodomain Proteins; Humans; Insulin-Secreting Cells; Mice; Nerve Tissue Proteins; Pluripotent Stem Cells; Thiazolidines; Trans-Activators; Tubulin Modulators | 2020 |
[Efficacy of Saxagliptin for Blood Glucose Control in Hemodialysis Patients with Diabetes].
Topics: Adamantane; Aged; Aged, 80 and over; Blood Glucose; Cost Savings; Diabetes Mellitus; Dipeptides; Drug Substitution; Female; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Linagliptin; Male; Middle Aged; Pilot Projects; Pyrazoles; Renal Dialysis; Serum Albumin; Thiazolidines | 2020 |
Extending the investigation of 4-thiazolidinone derivatives as potential multi-target ligands of enzymes involved in diabetes mellitus and its long-term complications: A study with pancreatic α-amylase.
Topics: Diabetes Mellitus; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Ligands; Molecular Structure; Pancreatic alpha-Amylases; Thiazolidines | 2021 |
Dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid in a patient with acquired reactive perforating collagenosis.
Topics: Aged; Autoantigens; Biopsy; Collagen Diseases; Collagen Type XVII; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Drug Substitution; Enzyme-Linked Immunosorbent Assay; Glycoside Hydrolase Inhibitors; Humans; Inositol; Male; Non-Fibrillar Collagens; Pemphigoid, Bullous; Pyrazoles; Skin; Thiazolidines | 2018 |
Short-term CFTR inhibition reduces islet area in C57BL/6 mice.
Topics: Animals; Benzoates; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diabetes Mellitus; Disease Models, Animal; Humans; Insulin; Insulin-Secreting Cells; Male; Mice; Thiazolidines | 2019 |
Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice.
Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Composition; Diabetes Mellitus; Diet, High-Fat; Dipeptidyl Peptidase 4; Eating; Energy Metabolism; Enzyme Inhibitors; Female; Glucagon-Like Peptide 1; Glucose Tolerance Test; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Random Allocation; Thiazolidines; Treatment Outcome; Valine; Weight Gain | 2014 |
Synthesis and in vivo antidiabetic activity of novel dispiropyrrolidines through [3+2] cycloaddition reactions with thiazolidinedione and rhodanine derivatives.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Drug Design; Humans; Hypoglycemic Agents; Insulin; Ligands; Male; Models, Molecular; Molecular Conformation; Pyrrolidines; Rats; Rats, Wistar; Rhodanine; Thiazolidines | 2009 |
Bicyclic cyanothiazolidines as novel dipeptidyl peptidase 4 inhibitors.
Topics: Azabicyclo Compounds; Catalysis; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Drug Design; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Nitriles; Protein Structure, Tertiary; Pyrrolidines; Structure-Activity Relationship; Thiazoles; Thiazolidines; Time Factors | 2009 |
Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study.
Topics: Adipocytes; Animals; Diabetes Mellitus; Dipeptidyl Peptidase 4; Drug Administration Schedule; Enzyme Inhibitors; Glucose Clamp Technique; Glucose Tolerance Test; Insulin; Lipolysis; Liver; Obesity; Pentanoic Acids; Rats; Rats, Zucker; Thiazoles; Thiazolidines | 2002 |
Combination therapy with PPARgamma and PPARalpha agonists increases glucose-stimulated insulin secretion in db/db mice.
Topics: Animals; Bezafibrate; Body Weight; Diabetes Mellitus; Drug Therapy, Combination; Glucose; Glucose Transporter Type 2; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Monosaccharide Transport Proteins; Pancreas; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors | 2003 |
From molecular footprints of disease to new therapeutic interventions in diabetic nephropathy.
Topics: Animals; Antioxidants; Biomarkers; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Guanidines; Humans; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thiadiazoles; Thiazolidines | 2005 |
Tissue-specific actions of antidiabetic thiazolidinediones on the reduced fatty acid oxidation in skeletal muscle and liver of Zucker diabetic fatty rats.
Topics: Administration, Oral; Animals; Chromans; Diabetes Mellitus; Fatty Acids; Hypoglycemic Agents; Liver; Male; Muscle, Skeletal; Obesity; Oxidation-Reduction; Palmitic Acid; Rats; Rats, Zucker; Reference Values; Substrate Specificity; Thiazoles; Thiazolidinediones; Thiazolidines; Triglycerides; Troglitazone | 2000 |
Pharmacological properties of fidarestat, a potent aldose reductase inhibitor, clarified by using sorbitol in human and rat erythrocytes.
Topics: Age Factors; Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Fasting; Female; Glycated Hemoglobin; Humans; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Rhodanine; Sciatic Nerve; Sex Factors; Sorbitol; Thiazolidines | 2001 |
In vitro retinal and erythrocyte polyol pathway regulation by hormones and an aldose reductase inhibitor.
Topics: Aged; Aldehyde Reductase; Animals; Diabetes Mellitus; Epinephrine; Erythrocytes; Fructose; Glucose; Humans; In Vitro Techniques; Insulin; Male; Rabbits; Reference Values; Retina; Rhodanine; Sorbitol; Thiazolidines | 1991 |
The role of the polyol pathway in diabetes mellitus.
Topics: Aldehyde Reductase; Diabetes Complications; Diabetes Mellitus; Glycolysis; Glycosylation; Humans; Hyperglycemia; Imidazoles; Imidazolidines; Naphthalenes; Phthalazines; Rhodanine; Thiazolidines | 1991 |