Page last updated: 2024-08-21

thiazolidines and Bone Loss, Osteoclastic

thiazolidines has been researched along with Bone Loss, Osteoclastic in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boonen, S; Deacon, S; Eastell, R; Kuwayama, T; Nagase, S; Ohyama, M; Small, M; Spector, T1
Deacon, S; Hashimoto, Y; Kuwayama, T; Manako, J; Nagase, S; Ohyama, M; Sharpe, J; Small, M1
Gamsjäger, M; Resch, H1
Deacon, S; Dijk, DJ; Eastell, R; Greenwood, A; Sharpe, J; Small, M; Tanimoto, M; Yamada, H; Yuba, M1
Hashimoto, Y; Kawabata, K; Kawada, N; Kayasuga, R; Kunishige, A; Mori, H; Nakanishi, Y; Nishikawa, S; Ochi, Y; Sugitani, M; Tanaka, M; Yamada, H1
Boonen, S; Claessens, F; Papapoulos, S; Rosenberg, E; Vanderschueren, D1
Deacon, S; Hashimoto, Y; Kuwayama, T; Nagase, S; Ohyama, M; Small, M1

Reviews

2 review(s) available for thiazolidines and Bone Loss, Osteoclastic

ArticleYear
[Cathepsin K antagonists: preclinical and clinical data].
    Wiener medizinische Wochenschrift (1946), 2015, Volume: 165, Issue:3-4

    Topics: Biphenyl Compounds; Bone Density; Bone Density Conservation Agents; Bone Resorption; Cathepsin K; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Osteoclasts; Osteoporosis, Postmenopausal; Thiazolidines

2015
Inhibition of cathepsin K for treatment of osteoporosis.
    Current osteoporosis reports, 2012, Volume: 10, Issue:1

    Topics: Alkaline Phosphatase; Animals; Biphenyl Compounds; Bone Density; Bone Remodeling; Bone Resorption; Cathepsin K; Humans; Osteoporosis; Osteoporosis, Postmenopausal; Thiazolidines

2012

Trials

4 trial(s) available for thiazolidines and Bone Loss, Osteoclastic

ArticleYear
Effect of ONO-5334 on bone mineral density and biochemical markers of bone turnover in postmenopausal osteoporosis: 2-year results from the OCEAN study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, Volume: 29, Issue:2

    Topics: Aged; Alendronate; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Resorption; Cathepsin K; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteogenesis; Osteoporosis, Postmenopausal; Thiazolidines; Time Factors

2014
Bone turnover markers and pharmacokinetics of a new sustained-release formulation of the cathepsin K inhibitor, ONO-5334, in healthy post-menopausal women.
    Journal of bone and mineral metabolism, 2015, Volume: 33, Issue:1

    Topics: Aged; Alendronate; Area Under Curve; Bone and Bones; Bone Density; Bone Resorption; Cathepsin K; Collagen Type I; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Middle Aged; Osteoporosis; Postmenopause; Single-Blind Method; Thiazolidines

2015
Morning vs evening dosing of the cathepsin K inhibitor ONO-5334: effects on bone resorption in postmenopausal women in a randomized, phase 1 trial.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016, Volume: 27, Issue:1

    Topics: Aged; Biomarkers; Bone Density Conservation Agents; Bone Resorption; Cathepsin K; Circadian Clocks; Collagen Type I; Cross-Over Studies; Drug Administration Schedule; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Postmenopause; Single-Blind Method; Thiazolidines

2016
Serum and urine bone resorption markers and pharmacokinetics of the cathepsin K inhibitor ONO-5334 after ascending single doses in post menopausal women.
    British journal of clinical pharmacology, 2012, Volume: 74, Issue:6

    Topics: Administration, Oral; Aged; Area Under Curve; Biomarkers; Bone Resorption; Cathepsin K; Collagen Type I; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Postmenopause; Thiazolidines

2012

Other Studies

1 other study(ies) available for thiazolidines and Bone Loss, Osteoclastic

ArticleYear
Effects of ONO-5334, a novel orally-active inhibitor of cathepsin K, on bone metabolism.
    Bone, 2011, Volume: 49, Issue:6

    Topics: Actins; Administration, Oral; Animals; Biomarkers; Bone and Bones; Bone Remodeling; Bone Resorption; Calcium; Cathepsin K; Collagen Type I; Female; Haplorhini; Humans; Male; Osteogenesis; Parathyroidectomy; Peptides; Protease Inhibitors; Rats; Thiazolidines

2011