thiazoles has been researched along with Thrombocytopenia in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (5.19) | 18.7374 |
| 1990's | 12 (15.58) | 18.2507 |
| 2000's | 12 (15.58) | 29.6817 |
| 2010's | 27 (35.06) | 24.3611 |
| 2020's | 22 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Markham, A | 1 |
| Arai, T; Arase, Y; Atsukawa, M; Furuichi, Y; Hidaka, H; Itoi, T; Kako, M; Takeuchi, H; Uojima, H | 1 |
| Al-Samkari, H; Jamieson, BD; Kolb-Sielecki, J; Safina, SZ; Xue, X | 1 |
| Arif, AR; Chen, W; Luo, S; Wang, Y; Xue, M; Zhao, M | 1 |
| Biolato, M; Grieco, A; Marrone, G; Miele, L; Vitale, F | 1 |
| Bussel, JB; Jamieson, BD; Lee, EJ; Tarantino, MD | 1 |
| Lebowa, W; Sacha, T; Zdziarska, J | 1 |
| Akahane, T; Fujinaga, Y; Ishida, K; Kaji, K; Kawaratani, H; Kaya, D; Kubo, T; Moriya, K; Namisaki, T; Sawada, Y; Shimozato, N; Takaya, H; Tsuji, Y; Yoshiji, H | 1 |
| Alkhouri, N; Bentley, R; Imawari, M; Izumi, N; Kano, T; Ochiai, T; Osaki, Y; Trevisani, F | 1 |
| Flamm, SL; Nilles, KM | 1 |
| Arase, Y; Atsukawa, M; Hidaka, H; Horie, R; Itokawa, N; Iwakiri, K; Iwasaki, S; Kagawa, T; Kako, M; Koizumi, W; Miyazaki, K; Okina, S; Satoh, T; Shao, X; Suzuki, T; Takiguchi, H; Uojima, H; Wada, N | 1 |
| Asama, H; Fukushima, T; Kawano, K; Kobayashi, S; Maeda, S; Morimoto, M; Nagashima, S; Ohkawa, S; Sano, Y; Tanaka, S; Ueno, M | 1 |
| Al-Samkari, H; Kuter, DJ; Virk, ZM | 1 |
| Al, M; Armstrong, N; Buksnys, T; Büyükkaramikli, N; Drachen, T; Duffy, S; Huertas Carrera, V; Kleijnen, J; Penton, H; Raatz, H; Riemsma, R; Ryder, S; Shah, D; Swift, S; Wetzelaer, P; Worthy, G | 1 |
| Gabrail, N; Smith, C | 1 |
| Lozano, ML | 1 |
| Isoda, N; Koyashiki, Y; Kurata, H; Maeda, H; Miura, K; Morimoto, N; Nomoto, H; Numao, N; Sasaki, T; Takaoka, Y; Watanabe, S; Yamamoto, H | 1 |
| Ishibashi, K; Kaneko, T; Takano, Y | 1 |
| Afdhal, N; Bentley, R; Giannini, EG; Kano, T; Ochiai, T; Shrestha, P | 1 |
| Buscarini, E; Dinis-Ribeiro, M; Fuccio, L; Hassan, C; Radaelli, F | 1 |
| Bussel, JB; Lee, EJ; Seshadri, M | 1 |
| Bubalo, J; Gilreath, J; Lo, M | 1 |
| Abe, S; Kamimura, K; Kawai, H; Sakamaki, A; Takamura, M; Terai, S; Tsuchiya, A; Watanabe, T; Yamagiwa, S | 1 |
| Ishimura, N; Isoda, K; Kataoka, M; Kinoshita, Y; Miyake, T; Sato, S; Tobita, H; Yazaki, T | 1 |
| Ferry, J; Hussein, Z; Nomoto, M | 1 |
| Shirley, M | 1 |
| Fukuhara, T; Imawari, M; Izumi, N; Kano, T; Katsube, T; Kawazoe, S; Kudo, M; Kurokawa, M; Ochiai, T; Osaki, Y; Seike, M; Tamai, H; Tanaka, K; Tateishi, R; Yamamoto, K | 1 |
| Aschenbrenner, DS | 1 |
| Allen, LF; Kuter, DJ | 1 |
| Carmichael, SL; Forde, EE; Frelinger, AL; Michelson, AD; Smolensky Koganov, E | 1 |
| Katano, T; Mizuta, K; Okada, N; Sanada, Y | 1 |
| Weinberg, EM | 1 |
| Abiru, S; Fukuhara, T; Hidaka, H; Igura, T; Imawari, M; Ishikawa, T; Izumi, N; Kano, T; Katsube, T; Kimura, K; Kudo, M; Kurokawa, M; Kurosaki, M; Nagata, T; Ochiai, T; Osaki, Y; Seike, M; Tanaka, H; Tanaka, K; Yamamoto, K | 1 |
| Al-Samkari, H | 1 |
| Enomoto, N; Higuchi, M; Itakura, J; Izumi, N; Komiyama, Y; Kubota, Y; Kurosaki, M; Nakanishi, H; Okada, M; Shimizu, T; Takada, H; Takahashi, Y; Takaura, K; Tamaki, N; Tsuchiya, K; Wang, W; Watakabe, K; Yasui, Y | 1 |
| Fukuhara, T; Kano, T; Katsube, T; Shimizu, R; Wajima, T | 1 |
| Al-Horani, RA; Clemons Bankston, P | 1 |
| Borchmann, P; Engert, A; Monsef, I; Rancea, M; Skoetz, N; Will, A | 1 |
| Beckers, MM; Daenen, S; Doorduijn, JK; Doreen Te Raa, G; Eldering, E; Kater, AP; Lankheet, NA; Liu, RD; Luijks, DM; Slinger, E; Spiering, M; Tonino, SH; van Oers, MH | 1 |
| Li, JY; Qiu, ZY; Xu, W | 1 |
| Hassanein, T; Howell, CD; Jenkins, TM; Joshi, S; Lake, J; McIntosh, J; Sher, L; Tang, S; Terrault, NA; Vargas, H | 1 |
| Bissonnette, J; Rautou, PE; Valla, D | 1 |
| de Knegt, RJ; Maan, R; Veldt, BJ | 1 |
| Kim, ES | 1 |
| Asahara, T; Izumi, M; Izumi, Y; Jiuchi, Y; Kozuru, H; Kumagai, K; Mawatari, M; Migita, K; Motokawa, S; Osaki, M; Sakai, T; Shirakawa, A | 1 |
| Abe, M; Fukushima-Shintani, M; Hirayama, F; Iwatsuki, Y; Kawasaki, T; Sugasawa, K; Suzuki, K | 1 |
| Snyder, DS | 1 |
| Awais, A; Borthakur, G; Cortes, J; De Souza Santos, FP; Faderl, S; Kantarjian, H; O'Brien, S; Quintás-Cardama, A | 1 |
| Ghevaert, C; Massberg, S; Mazharian, A; Watson, SP; Zhang, L | 1 |
| Kim, HS; Kwak, JY; Lee, NR; Song, EK; Yhim, HY; Yim, CY | 1 |
| Andreoli, A; Anselem, O; Berveiller, P; Chapuis, N; Delezoide, AL; Mir, O; Sauvageon, H; Tsatsaris, V | 1 |
| Cervantes, F; le Coutre, P; Porkka, K; Saglio, G; Steegmann, JL | 1 |
| Figuerres, E; Kletzel, M; Olszewski, M | 1 |
| Hanahachi, A; Hasegawa, A; Kano, R; Kurashige, A; Okamura, T; Tsujimoto, H | 1 |
| Hasegawa, A; Kano, R; Michimoto, T; Okamura, T; Suzuki, K; Watari, T | 1 |
| Degan, M; Guidi, GC; Marradi, PL; Minuz, P; Montagnana, M; Poli, G; Ricetti, MM; Riolfi, P; Salvagno, GL; Santonastaso, CL | 1 |
| Aramori, I; Fujimura, T; Matsuoka, H; Mori, H; Mutoh, S; Noto, T; Takata, Y; Unami, A; Yamada, T; Yoshizawa, K | 1 |
| Colgan, JP; Ferguson, RH; O'Duffy, JD; Phyliky, RL | 1 |
| Ault, KA; Bonan, JL; Munz, UJ; Rinder, HM; Smith, BR | 1 |
| Hérault, JP; Herbert, JM; Lalé, A; Pflieger, AM; Savi, P | 1 |
| Barbosa-Filho, JM; Castro-Faria-Neto, HC; Cordeiro, RS; Herbert, JM; Tibiriça, E | 1 |
| Grindem, CB; Perkins, PC; Russell, KE; Sellon, DC; Walker, KM | 1 |
| Bakhos, M; Ero, M; Haas, S; Herbert, JM; Jeske, WP; Szatkowski, E; Walenga, JM | 1 |
| Bernat, A; Herbert, JM; Hoffmann, P; Savi, P | 1 |
| Herbert, JM; Jeske, WP; Savi, P; Walenga, JM | 1 |
| Manda, T; Matsuo, M; Nishigaki, F; Ogino, T; Sawada, M; Seki, N; Sudo, Y; Tsuji, K | 1 |
| Hayashi, S; Honda, S; Kashiwagi, H; Kiyoi, T; Kurata, Y; Oshida, M; Tadokoro, S; Tomiyama, Y | 1 |
| Fujii, T; Fujimoto, TT; Fujimura, K; Kimura, A; Shimomura, T | 1 |
| Javela, K; Joutsi-Korhonen, L; Kekomäki, R; Riikonen, S; Sainio, S; Teramo, K | 1 |
| Hanahachi, A; Hasegawa, A; Kano, R; Moritomo, T; Tsujimoto, H; Watari, T | 1 |
| Smith, R; Thomas, JS | 1 |
| Ault, KA; Carmody, MB; Hillman, RS; Mitchell, J; Rinder, HM; Vary, CP | 1 |
| Bernat, A; Gigo, V; Herbert, JM; Lale, A; LaPlace, MC; Le Fur, G; Lespy, L; Maffrand, JP; Savi, P; Valette, G | 1 |
| Kienast, J; Schmitz, G | 1 |
| Comer, JB; Evans, JA; Kerns, A | 1 |
| Handley, DA; Saunders, RN; Van Valen, RG | 1 |
| Issekutz, AC; Szpejda, M | 1 |
13 review(s) available for thiazoles and Thrombocytopenia
| Article | Year |
|---|---|
Avatrombopag: A Review in Thrombocytopenia.
Topics: Adult; Animals; Chronic Disease; Humans; Liver Diseases; Purpura, Thrombocytopenic, Idiopathic; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombocytopenia | 2021 |
Lusutrombopag Is Safe and Efficacious for Treatment of Thrombocytopenia in Patients With and Without Hepatocellular Carcinoma.
Topics: Carcinoma, Hepatocellular; Cinnamates; Humans; Liver Neoplasms; Thiazoles; Thrombocytopenia | 2020 |
Thrombocytopenia in Chronic Liver Disease: New Management Strategies.
Topics: Chronic Disease; Cinnamates; Hemorrhage; Humans; Liver Diseases; Platelet Count; Platelet Transfusion; Receptors, Thrombopoietin; Risk Factors; Surgical Procedures, Operative; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoiesis | 2020 |
Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis.
Topics: Bayes Theorem; Cinnamates; Clinical Trials as Topic; Cost-Benefit Analysis; End Stage Liver Disease; Humans; Models, Economic; Platelet Transfusion; Quality-Adjusted Life Years; Receptors, Thrombopoietin; Secondary Care; Technology Assessment, Biomedical; Thiazoles; Thiophenes; Thrombocytopenia | 2020 |
Avatrombopag for the management of thrombocytopenia in patients with chronic liver disease.
Topics: Adult; Chronic Disease; Humans; Liver Diseases; Thiazoles; Thiophenes; Thrombocytopenia | 2021 |
Thrombopoietin Receptor Agonists (TPO-RAs): Drug Class Considerations for Pharmacists.
Topics: Benzoates; Cinnamates; Dose-Response Relationship, Drug; Drug Monitoring; Health Knowledge, Attitudes, Practice; Humans; Hydrazines; Pharmacists; Platelet Count; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin | 2021 |
Avatrombopag: First Global Approval.
Topics: Chronic Disease; Drug Approval; Humans; Liver Diseases; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombocytopenia; United States; United States Food and Drug Administration | 2018 |
Avatrombopag maleate for the treatment of periprocedural thrombocytopenia in patients with chronic liver disease.
Topics: Animals; Chronic Disease; Drug Interactions; Hematologic Agents; Humans; Liver Diseases; Perioperative Period; Thiazoles; Thiophenes; Thrombocytopenia; Treatment Outcome | 2018 |
New Small Molecule Drugs for Thrombocytopenia: Chemical, Pharmacological, and Therapeutic Use Considerations.
Topics: Aminopyridines; Animals; Cinnamates; Drug Development; Humans; Morpholines; Oxazines; Pyridines; Pyrimidines; Receptors, Thrombopoietin; Small Molecule Libraries; Syk Kinase; Thiazoles; Thiophenes; Thrombocytopenia | 2019 |
Large granular lymphocytosis during dasatinib therapy.
Topics: Antineoplastic Agents; Clone Cells; Colitis; Dasatinib; Familial Primary Pulmonary Hypertension; Humans; Killer Cells, Natural; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphocytosis; Pleural Effusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; T-Lymphocytes, Cytotoxic; Thiazoles; Thrombocytopenia | 2014 |
Management of Thrombocytopenia in Chronic Liver Disease: Focus on Pharmacotherapeutic Strategies.
Topics: Benzoates; Chronic Disease; Disease Management; Hepatitis C, Chronic; Humans; Hydrazines; Liver Diseases; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin | 2015 |
New approved dasatinib regimen available for clinical use.
Topics: Clinical Trials, Phase III as Topic; Dasatinib; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Chronic-Phase; Pleural Effusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Thrombocytopenia | 2009 |
Off-target effects of BCR-ABL1 inhibitors and their potential long-term implications in patients with chronic myeloid leukemia.
Topics: Benzamides; Dasatinib; Diarrhea; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Thiazoles; Thrombocytopenia; Time Factors | 2012 |
14 trial(s) available for thiazoles and Thrombocytopenia
| Article | Year |
|---|---|
Avatrombopag for chemotherapy-induced thrombocytopenia in patients with non-haematological malignancies: an international, randomised, double-blind, placebo-controlled, phase 3 trial.
Topics: Adolescent; Anemia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Double-Blind Method; Humans; Neutropenia; Thiazoles; Thiophenes; Thrombocytopenia; Treatment Outcome | 2022 |
Plasma gastric biomarker evaluation with avatrombopag dosing in patients with chronic immune thrombocytopenia in phase 3 trials.
Topics: Humans; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Thiazoles; Thrombocytopenia | 2023 |
Effectiveness of Lusutrombopag in Patients with Mild to Moderate Thrombocytopenia.
Topics: Aged; Cinnamates; Female; Humans; Male; Platelet Count; Postoperative Complications; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia; Time Factors; Treatment Outcome | 2020 |
Impact of Anti-GPIIb/IIIa Antibody-Producing B Cells as a Predictor of the Response to Lusutrombopag in Thrombocytopenic Patients with Liver Disease.
Topics: Aged; Aged, 80 and over; Autoantibodies; B-Lymphocytes; Blood Platelets; Cinnamates; Female; Humans; Liver Diseases; Male; Middle Aged; Multivariate Analysis; Organ Size; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Spleen; Thiazoles; Thrombocytopenia | 2021 |
A randomized controlled trial of lusutrombopag in Japanese patients with chronic liver disease undergoing radiofrequency ablation.
Topics: Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Chronic Disease; Cinnamates; Double-Blind Method; Female; Half-Life; Humans; Japan; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Platelet Count; Platelet Transfusion; Preoperative Care; Radiofrequency Ablation; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia; Thrombosis | 2019 |
Avatrombopag, an oral thrombopoietin receptor agonist: results of two double-blind, dose-rising, placebo-controlled Phase 1 studies.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombocytopenia | 2018 |
Avatrombopag increases platelet count but not platelet activation in patients with thrombocytopenia resulting from liver disease.
Topics: Blood Platelets; Chronic Disease; Double-Blind Method; Hematologic Agents; Humans; Liver Diseases; Platelet Activation; Platelet Count; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoiesis; Time Factors; Treatment Outcome; United States | 2018 |
Lusutrombopag Reduces Need for Platelet Transfusion in Patients With Thrombocytopenia Undergoing Invasive Procedures.
Topics: Aged; Catheter Ablation; Cinnamates; Double-Blind Method; Female; Follow-Up Studies; Humans; Incidence; Japan; Liver Cirrhosis; Male; Platelet Transfusion; Postoperative Hemorrhage; Retrospective Studies; Thiazoles; Thrombocytopenia; Treatment Outcome | 2019 |
Dasatinib in combination with fludarabine in patients with refractory chronic lymphocytic leukemia: a multicenter phase 2 study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dasatinib; Drug Administration Schedule; Fatigue; Female; Gene Expression Regulation, Leukemic; Humans; Kaplan-Meier Estimate; Leukemia, Lymphocytic, Chronic, B-Cell; Lymph Nodes; Male; Middle Aged; Nausea; NF-kappa B; Pneumonia; Pyrimidines; Thiazoles; Thrombocytopenia; Treatment Outcome; Vidarabine | 2014 |
Phase II study of avatrombopag in thrombocytopenic patients with cirrhosis undergoing an elective procedure.
Topics: Blood Platelets; Dose-Response Relationship, Drug; Double-Blind Method; Elective Surgical Procedures; Fatigue; Female; Headache; Humans; Incidence; Liver Cirrhosis; Male; Middle Aged; Nausea; Platelet Count; Receptors, Thrombopoietin; Risk Factors; Thiazoles; Thiophenes; Thrombocytopenia | 2014 |
Reduced induction of anti-PF4/heparin antibody in RA patients after total knee arthroplasty.
Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Autoantibodies; Autoantigens; Enzyme-Linked Immunosorbent Assay; Factor Xa Inhibitors; Female; Humans; Immunoblotting; Immunoglobulin G; Male; Middle Aged; Osteoarthritis; Platelet Factor 4; Pyridines; Seroconversion; Thiazoles; Thrombocytopenia; Thromboembolism | 2016 |
Dynamics and management of cytopenias associated with dasatinib therapy in patients with chronic myeloid leukemia in chronic phase after imatinib failure.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Dasatinib; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Incidence; Intercellular Signaling Peptides and Proteins; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Neutropenia; Pyrimidines; Retreatment; Thiazoles; Thrombocytopenia; Treatment Outcome | 2009 |
Effect of SR121566A, a potent GP IIb-IIIa antagonist, on the HIT serum/heparin-induced platelet mediated activation of human endothelial cells.
Topics: Adenosine Diphosphate; Antibodies; Benzylamines; Cytokines; Endothelium, Vascular; Heparin; Humans; Membrane Proteins; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Reference Values; Risk Factors; Serotonin; Thiazoles; Thrombocytopenia | 1998 |
[Reticulated platelet determination: methodologies and applications for the evaluation of thrombocytopenic disorders].
Topics: Adult; Aged; Benzothiazoles; Diagnosis, Differential; Flow Cytometry; Fluorescent Dyes; Humans; Middle Aged; Platelet Count; Quinolines; Reproducibility of Results; Staining and Labeling; Thiazoles; Thrombocytopenia | 1999 |
50 other study(ies) available for thiazoles and Thrombocytopenia
| Article | Year |
|---|---|
Lusutrombopag has slightly stronger effects on patients with mild thrombocytopenia compared with those with severe thrombocytopenia: A multicenter propensity score matching study.
Topics: Cinnamates; Humans; Propensity Score; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia | 2022 |
Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure.
Topics: Benzoates; Hearing Loss, Sensorineural; Humans; Hydrazines; Male; Molecular Motor Proteins; Mutation; Myosin Heavy Chains; Pyrazoles; Thiazoles; Thiophenes; Thrombocytopenia; Treatment Failure | 2022 |
A single course of lusutrombopag for multiple invasive procedures in cirrhosis-associated thrombocytopenia: A case series.
Topics: Cinnamates; Humans; Liver Cirrhosis; Thiazoles; Thrombocytopenia | 2022 |
Avatrombopag increased platelet count in a patient with chronic immune thrombocytopenia refractory to multiple lines of treatment.
Topics: Adult; Child, Preschool; Humans; Male; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Thiazoles; Thrombocytopenia | 2023 |
Repeated Lusutrombopag Treatment for Thrombocytopenia in Patients with Chronic Liver Disease.
Topics: Chronic Disease; Cinnamates; Humans; Liver Diseases; Receptors, Thrombopoietin; Retrospective Studies; Thiazoles; Thrombocytopenia | 2021 |
An evaluation of avatrombopag for the treatment of thrombocytopenia.
Topics: Humans; Liver Diseases; Purpura, Thrombocytopenic, Idiopathic; Thiazoles; Thiophenes; Thrombocytopenia | 2021 |
Avatrombopag Optimizes Response to Niraparib by Managing Thrombocytopenia Associated with Poly-ADP Ribose Polymerase (PARP) Inhibition in Ovarian Cancer and Breast Cancer: A Case Series.
Topics: Adenosine Diphosphate Ribose; Breast Neoplasms; Female; Humans; Indazoles; Ovarian Neoplasms; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thiazoles; Thiophenes; Thrombocytopenia | 2020 |
Lusutrombopag is effective and safe in patients with chronic liver disease and severe thrombocytopenia: a multicenter retrospective study.
Topics: Cinnamates; Humans; Liver Diseases; Receptors, Thrombopoietin; Retrospective Studies; Thiazoles; Thrombocytopenia | 2020 |
Lusutrombopag as a substitute for platelet transfusion for thrombocytopenia associated with chronic liver disease in a patient undergoing endoscopic spinal surgery: A case report.
Topics: Aged; Blood Loss, Surgical; Cinnamates; End Stage Liver Disease; Endoscopy; Female; Humans; Lumbar Vertebrae; Spinal Fractures; Thiazoles; Thrombocytopenia | 2021 |
Bleeding events in lusutrombopag-treated thrombocytopenic patients.
Topics: Aged; Biopsy; Blood Loss, Surgical; Chemoembolization, Therapeutic; Chronic Disease; Cinnamates; Endoscopy, Digestive System; Female; Humans; Liver Diseases; Male; Middle Aged; Perioperative Care; Platelet Transfusion; Postoperative Hemorrhage; Radiofrequency Ablation; Randomized Controlled Trials as Topic; Receptors, Thrombopoietin; Retrospective Studies; Thiazoles; Thrombocytopenia; Tooth Extraction | 2021 |
Second-generation thrombopoietin receptor agonists: New players in the management of cirrhotic patients undergoing therapeutic endoscopy?
Topics: Cinnamates; Endoscopy; Humans; Liver Cirrhosis; Receptors, Thrombopoietin; Surveys and Questionnaires; Thiazoles; Thiophenes; Thrombocytopenia | 2021 |
Clinical outcomes in eight patients with immune thrombocytopenia each treated with the three approved thrombopoietin receptor agonists.
Topics: Adult; Aged; Benzoates; Female; Humans; Hydrazines; Male; Middle Aged; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin; Treatment Outcome | 2021 |
Lusutrombopag increases hematocytes in a compensated liver cirrhosis patient.
Topics: Carcinoma, Hepatocellular; Cinnamates; Hepatitis C; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Thiazoles; Thrombocytopenia | 2017 |
Efficacy of Repeated Lusutrombopag Administration for Thrombocytopenia in a Patient Scheduled for Invasive Hepatocellular Carcinoma Treatment.
Topics: Carcinoma, Hepatocellular; Chronic Disease; Cinnamates; Female; Humans; Liver Diseases; Liver Neoplasms; Middle Aged; Platelet Count; Thiazoles; Thrombocytopenia | 2017 |
Population Pharmacokinetic/Pharmacodynamic Analyses of Avatrombopag in Patients With Chronic Liver Disease and Optimal Dose Adjustment Guide With Concomitantly Administered CYP3A and CYP2C9 Inhibitors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Computer Simulation; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; End Stage Liver Disease; Female; Humans; Male; Middle Aged; Models, Biological; Thiazoles; Thiophenes; Thrombocytopenia; Young Adult | 2018 |
First Drug Approved to Reduce Bleeding Risk During Medical Procedures in Patients with Chronic Liver Disease.
Topics: Drug Approval; End Stage Liver Disease; Humans; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombocytopenia | 2018 |
Lusutrombopag as pretreatment for liver biopsy following liver transplantation.
Topics: Adolescent; Biopsy; Cinnamates; Humans; Liver; Liver Transplantation; Living Donors; Male; Platelet Count; Preoperative Care; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia | 2018 |
What Did We Learn From the ADAPT Trials?
Topics: Humans; Liver Diseases; Platelet Transfusion; Thiazoles; Thiophenes; Thrombocytopenia | 2019 |
Real-life experience of lusutrombopag for cirrhotic patients with low platelet counts being prepared for invasive procedures.
Topics: Aged; Carcinoma, Hepatocellular; Catheter Ablation; Chemoembolization, Therapeutic; Cinnamates; Esophageal and Gastric Varices; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Platelet Count; Platelet Transfusion; Receptors, Thrombopoietin; Retrospective Studies; Sclerotherapy; Thiazoles; Thrombocytopenia | 2019 |
Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Lusutrombopag, a Novel Thrombopoietin Receptor Agonist, for the Treatment of Thrombocytopenia in Patients with Chronic Liver Disease Undergoing Invasive Procedures.
Topics: Adult; Aged; Aged, 80 and over; Blood Platelets; Chronic Disease; Cinnamates; Female; Humans; Liver Diseases; Male; Middle Aged; Models, Biological; Platelet Count; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia; Young Adult | 2019 |
Fifteenth biannual report of the Cochrane Haematological Malignancies Group--focus on non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bleomycin; Cyclophosphamide; Dasatinib; Doxorubicin; Etoposide; Hodgkin Disease; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Non-Hodgkin; Middle Aged; Multicenter Studies as Topic; Multiple Myeloma; Neoplasm Staging; Piperazines; Platelet Transfusion; Prednisone; Primary Prevention; Procarbazine; Pyrimidines; Randomized Controlled Trials as Topic; Rituximab; Stem Cell Transplantation; Survival Analysis; Thiazoles; Thrombocytopenia; Transplantation, Autologous; Treatment Outcome; Vincristine; Vindesine | 2013 |
Managing periprocedural thrombocytopenia in cirrhosis: aiming for a safety window.
Topics: Elective Surgical Procedures; Female; Humans; Liver Cirrhosis; Male; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombocytopenia | 2014 |
Lusutrombopag: First Global Approval.
Topics: Cinnamates; Drug Approval; Humans; Japan; Liver Diseases; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia | 2016 |
AKR-501 (YM477) in combination with thrombopoietin enhances human megakaryocytopoiesis.
Topics: Antigens, CD; Antigens, CD34; Blood Platelets; Cells, Cultured; Colony-Forming Units Assay; Flow Cytometry; Humans; Piperidines; Receptors, Thrombopoietin; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoiesis; Thrombopoietin | 2008 |
Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation.
Topics: Animals; Blood Platelets; Cell Differentiation; Cell Movement; Cell Separation; Dasatinib; Flow Cytometry; Immunohistochemistry; Megakaryocytes; Mice; Mice, Inbred C57BL; Ploidies; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Thrombocytopenia; Thrombopoiesis | 2011 |
Bilateral subdural hemorrhage as a serious adverse event of dasatinib in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Dasatinib; Female; Hemorrhage; Humans; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; Subdural Space; Thiazoles; Thrombocytopenia | 2012 |
A dramatic fetal outcome following transplacental transfer of dasatinib.
Topics: Dasatinib; Female; Fetus; Humans; Hydrops Fetalis; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukopenia; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Neoplastic; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Thrombocytopenia; Treatment Outcome; Young Adult | 2012 |
A flow cytometric technique using thiazole orange to detect platelet engraftment following pediatric stem-cell transplants.
Topics: Adolescent; Adult; Benzothiazoles; Blood Platelets; Bone Marrow Transplantation; Child; Child, Preschool; Fetal Blood; Flow Cytometry; Fluorescent Dyes; Graft Survival; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Infant, Newborn; Platelet Count; Platelet Transfusion; Predictive Value of Tests; Quinolines; Reproducibility of Results; RNA; Thiazoles; Thrombocytopenia; Treatment Outcome | 2001 |
Thiazole orange-positive platelets in cats with thrombocytopenia induced by cyclophosphamide.
Topics: Animals; Antineoplastic Agents, Alkylating; Benzothiazoles; Blood Platelets; Cat Diseases; Cats; Cyclophosphamide; Female; Flow Cytometry; Fluorescent Dyes; Infusions, Intravenous; Male; Quinolines; Thiazoles; Thrombocytopenia | 2003 |
Thiazole orange positive platelets in a dog with Evans' syndrome.
Topics: Anemia, Hemolytic; Animals; Benzothiazoles; Blood Platelets; Dog Diseases; Dogs; Female; Flow Cytometry; Prednisolone; Quinolines; Syndrome; Thiazoles; Thrombocytopenia | 2004 |
Evaluation of platelet turnover by flow cytometry.
Topics: Adolescent; Adult; Aged; Benzothiazoles; Blood Cell Count; Blood Platelets; Child; Child, Preschool; Endoplasmic Reticulum; Female; Flow Cytometry; Humans; Kinetics; Male; Middle Aged; Quinolines; Statistics, Nonparametric; Thiazoles; Thrombocytopenia | 2006 |
Novel method for selecting immunosuppressive histone deacetylase (HDAC) inhibitors with minimal thrombocytopenia.
Topics: Animals; Cell Survival; Drug Evaluation, Preclinical; Enzyme Inhibitors; GATA1 Transcription Factor; Genes, Reporter; Heart Transplantation; Histone Deacetylase Inhibitors; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Male; Plasmids; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Thrombocytopenia; Transplantation, Heterotopic | 2008 |
Frentizole therapy of thrombocytopenia in systemic lupus erythematosus and refractory idiopathic thrombocytopenic purpura.
Topics: Adult; Benzothiazoles; Double-Blind Method; Female; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Middle Aged; Phenylurea Compounds; Platelet Count; Prednisone; Purpura, Thrombocytopenic; Thiazoles; Thrombocytopenia | 1980 |
Reticulated platelets in the evaluation of thrombopoietic disorders.
Topics: Adult; Antibodies, Anti-Idiotypic; Antineoplastic Agents; Benzothiazoles; Blood Platelet Disorders; Blood Platelets; Flow Cytometry; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Immunoglobulin G; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Quinolines; Thiazoles; Thrombocytopenia | 1993 |
In vitro inhibition of heparin-induced platelet aggregation in plasma from patients with HIT by SR 121566, a newly developed Gp IIb/IIIa antagonist.
Topics: Benzylamines; Heparin; Humans; In Vitro Techniques; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thiazoles; Thrombocytopenia | 1997 |
Pharmacological evidence for the putative existence of two different subtypes of PAF receptors on platelets and leukocytes; studies with yangambin.
Topics: Animals; Blood Platelets; Furans; Guinea Pigs; Humans; Interleukin-1; Interleukin-6; Kinetics; Leukocytes; Leukopenia; Lignans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Thiazoles; Thrombocytopenia; Tumor Necrosis Factor-alpha | 1997 |
Flow cytometric method for detecting thiazole orange-positive (reticulated) platelets in thrombocytopenic horses.
Topics: Animals; Anticoagulants; Benzothiazoles; Blood Platelets; Bone Marrow; Citrates; Edetic Acid; Equine Infectious Anemia; Flow Cytometry; Fluorescent Dyes; Horse Diseases; Horses; Quinolines; Sodium Citrate; Thiazoles; Thrombocytopenia | 1997 |
Effect of glycoprotein IIb/IIIa antagonists on the HIT serum induced activation of platelets.
Topics: Benzylamines; Blood Platelets; Blood Proteins; Drug Interactions; Heparin; Humans; Immunoglobulin Fab Fragments; Piperidines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thiazoles; Thrombocytopenia | 1997 |
Prevention of thrombosis and enhancement of thrombolysis in rabbits by SR 121787, a glycoprotein II/III antagonist.
Topics: Animals; Aspirin; Benzylamines; Bleeding Time; Carotid Artery Injuries; Collagen; Fibrinolytic Agents; Hemostasis; In Vitro Techniques; Jugular Veins; Male; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Thiazoles; Thrombocytopenia; Thrombosis | 1998 |
Synthesis and effects of novel thiazole derivatives against thrombocytopenia.
Topics: Animals; Autoantibodies; Blood Platelets; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mitomycin; Models, Chemical; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Thiazoles; Thrombocytopenia | 1998 |
A new approach to detect reticulated platelets stained with thiazole orange in thrombocytopenic patients.
Topics: Benzothiazoles; Blood Platelets; Flow Cytometry; Humans; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Quinolines; Staining and Labeling; Thiazoles; Thrombocytopenia; Thrombocytosis | 2000 |
Detection of reticulated platelets: estimating the degree of fluorescence of platelets stained with thiazole orange.
Topics: Adult; Aged; Benzothiazoles; Blood Platelets; Cellular Senescence; Coloring Agents; Female; Flow Cytometry; Fluorescent Dyes; Gestational Age; Hematopoiesis; Humans; Infant, Newborn; Male; Middle Aged; Pregnancy; Pregnancy Complications, Hematologic; Quinolines; Single-Blind Method; Thiazoles; Thrombocytopenia | 2000 |
Thiazole orange-positive platelets in healthy and thrombocytopenic dogs.
Topics: Animals; Benzothiazoles; Blood Platelets; Bone Marrow; Case-Control Studies; Dog Diseases; Dogs; Flow Cytometry; Fluorescent Dyes; Platelet Count; Quinolines; Reference Values; Thiazoles; Thrombocytopenia | 2001 |
Quantitation of reticulated platelets in healthy dogs and in nonthrombocytopenic dogs with clinical disease.
Topics: Animals; Benzothiazoles; Blood Platelets; Dog Diseases; Dogs; Female; Flow Cytometry; Fluorescent Dyes; Male; Platelet Count; Quinolines; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Thiazoles; Thrombocytopenia | 2002 |
The significance of platelets with increased RNA content (reticulated platelets). A measure of the rate of thrombopoiesis.
Topics: Animals; Benzothiazoles; Blood Platelets; Fluorescent Dyes; Hematopoiesis; Humans; Immune System Diseases; Immunoglobulins; Mice; Mice, Inbred BALB C; Quinolines; Reference Values; Ribonucleases; RNA; Sensitivity and Specificity; Thiazoles; Thrombocytopenia | 1992 |
Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.
Topics: Animals; Azepines; Blood Platelets; Bronchoconstriction; Guinea Pigs; Humans; Injections, Intravenous; Leukopenia; Male; Mice; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thrombocytopenia; Triazoles | 1991 |
Flow cytometric analysis of thiazole orange uptake by platelets: a diagnostic aid in the evaluation of thrombocytopenic disorders.
Topics: Benzothiazoles; Biological Transport; Blood Platelets; Flow Cytometry; Humans; Megakaryocytes; Platelet Count; Quinolines; RNA; Thiazoles; Thrombocytopenia | 1990 |
Possible famotidine-induced thrombocytopenia.
Topics: Adult; Famotidine; Histamine H2 Antagonists; Humans; Male; Platelet Count; Thiazoles; Thrombocytopenia | 1989 |
Vascular responses of platelet-activating factor in the Cebus apella primate and inhibitory profiles of antagonists SRI 63-072 and SRI 63-119.
Topics: Animals; Cebus; Indomethacin; Lung; Macaca mulatta; Male; Papio; Platelet Activating Factor; Platelet Aggregation; Thiazoles; Thrombocytopenia; Thromboxane B2 | 1986 |
Evidence that platelet activating factor may mediate some acute inflammatory responses. Studies with the platelet-activating factor antagonist, CV3988.
Topics: Acute Disease; Animals; Blood Platelets; Capillary Permeability; Cell Movement; Inflammation; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Regional Blood Flow; Serum Albumin; Skin; Thiazoles; Thrombocytopenia | 1986 |