thiazoles has been researched along with Tay-Sachs Disease in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Almanasra, A; Havranek, B; Islam, SM | 1 |
| Cherney, MM; James, MN; Lemieux, MJ; Mahuran, DJ; Mark, BL; Withers, SG | 1 |
2 other study(ies) available for thiazoles and Tay-Sachs Disease
| Article | Year |
|---|---|
In-silico screening and microsecond molecular dynamics simulations to identify single point mutations that destabilize β-hexosaminidase A causing Tay-Sachs disease.
Topics: Acetylglucosamine; beta-Hexosaminidase alpha Chain; Binding Sites; Central Nervous System; G(M2) Ganglioside; Gene Expression; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Neurons; Peripheral Nervous System; Point Mutation; Polymorphism, Single Nucleotide; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Tay-Sachs Disease; Thermodynamics; Thiazoles | 2021 |
Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis.
Topics: Acetylglucosamine; Amino Acid Substitution; Arginine; Aspartic Acid; beta-N-Acetylhexosaminidases; Binding Sites; Crystallography, X-Ray; Dimerization; Gangliosidoses, GM2; Glycine; Glycosylation; Hexosaminidase A; Humans; Hydrolysis; Models, Molecular; Mutation; Protein Conformation; Protein Subunits; Tay-Sachs Disease; Thiazoles | 2006 |