thiazoles has been researched along with Tauopathies in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 18 (62.07) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Garmer, M; Jul, PH; Rostgaard, N; Volbracht, C | 1 |
| Baron, JC; Bottlaender, M; Caillé, F; Gervais, P; Lagarde, J; Olivieri, P; Sarazin, M | 1 |
| Amariglio, RE; d'Oleire Uquillas, F; Gatchel, J; Hanseeuw, B; Hedden, T; Jacobs, HIL; Johnson, KA; Papp, KV; Pascual-Leone, A; Rentz, DM; Sepulcre, J; Sperling, RA; Vannini, P | 1 |
| Butts, BD; Duffy, JL; Fred Hess, J; Grotz, D; Hargreaves, R; Hastings, NB; Hong, KK; Huang, CR; Hyde, L; Laverty, M; Lee, J; Levitan, D; Lu, SX; Maguire, M; Mahadomrongkul, V; McEachern, EJ; Ouyang, X; Parker, EM; Rosahl, TW; Selnick, H; Song, L; Stanton, M; Terracina, G; Vocadlo, DJ; Wang, G; Wang, X; Zhang, L | 1 |
| Aho, A; Biernat, J; Dennissen, FJA; Hübschmann, S; Mandelkow, E; Mandelkow, EM; Pickhardt, M; Timm, T | 1 |
| Aghjayan, SL; Amariglio, RE; Buckley, RF; Hanseeuw, B; Jackson, JD; Johnson, KA; Mormino, EC; Properzi, MJ; Rentz, DM; Schultz, AP; Sperling, RA; Vannini, P | 1 |
| Cosden, ML; Hess, JF; Hughes, A; Marcus, J; Pearson, M; Rosahl, T; Savage, MJ; Schachter, JB; Smith, K; Smith, SM; Uslaner, JM; Wang, X | 1 |
| Cornwell, ME; Cuny, GD; Hernandez, I; Kosik, KS; Laha, JK; Mair, W; Rei, D; Steen, JA; Tsai, LH; Zhang, X | 1 |
| Aoki, I; Chang, Q; Furumoto, S; Higuchi, M; Ito, H; Iwata, N; Jang, MK; Ji, B; Kudo, Y; Lee, VM; Lewis, J; Maeda, J; Maruyama, M; Masamoto, K; Okamura, N; Ono, M; Sahara, N; Saido, TC; Shimada, H; Shinotoh, H; Suhara, T; Takano, H; Takashima, A; Trojanowski, JQ; Zhang, MR | 1 |
| Carlson, GA; Dellovade, TL; Graham, DL; Gray, AJ; Hering, H; Joyce, JA; O'Moore, J; Shearman, MS; Yu, D | 1 |
| Borghgraef, P; Devijver, H; Gijsen, H; Hilaire, G; Lippens, G; Louis, JV; Maurin, H; Menuet, C; Moechars, D; Smet-Nocca, C; Theunis, C; Van Leuven, F | 1 |
| Baron, T; Billard, T; Bouillot, C; Chauveau, F; Lancelot, S; Levigoureux, E; Verchere, J; Verdurand, M; Zimmer, L | 1 |
| Haque, MM; Kim, YK; Lim, S; Nam, G; Rhim, H; Ryoo, N | 1 |
| Callaway, K; Dobson, CM; Mandelkow, E; Mandelkow, EM; McConlogue, L; Neumann, T; Pickhardt, M; Schenk, D; Schwizer, D; St George-Hyslop, P; Tóth, G; Vendruscolo, M | 1 |
| Amariglio, R; Hanseeuw, B; Hedden, T; Johnson, KA; LaPoint, M; Marshall, GA; Mormino, EC; Papp, KV; Rentz, DM; Schultz, AP; Sperling, RA | 1 |
| Bulic, B; Mandelkow, E; Mandelkow, EM; Pickhardt, M; Schmidt, B; Waldmann, H | 1 |
| Cassell, MD; Ding, SL; Poremba, A; Van Hoesen, GW | 1 |
| Haddix, T; Lee, VM; Nakashima-Yasuda, H; Robinson, J; Trojanowski, JQ; Uryu, K | 1 |
| Bresjanac, M; Kovacs, GG; Mohorko, N; Popović, M; Repovs, G | 1 |
| Baumeister, R; Biernat, J; Fatouros, C; Koushika, SP; Mandelkow, E; Mandelkow, EM; Pir, GJ; Schmidt, E | 1 |
| Hayashi, S; Ihara, M; Kimura, H; Matsumura, K; Mori, H; Okamoto, Y; Ono, M; Saji, H; Takahashi, R | 1 |
| Bellmann, C; Giasson, BI; Horiguchi, T; Ischiropoulos, H; Lee, VM; LightFoot, R; Richter-Landsberg, C; Trojanowski, JQ; Uryu, K | 1 |
| Dabir, D; Forman, MS; Goldbaum, O; Handschuh, M; Lee, VM; Oppermann, M; Richter-Landsberg, C; Trojanowski, JQ; Zhang, B | 1 |
| Asuni, AA; Berg, S; Bhat, R; Drummond, JA; Jukes, JP; Lovestone, S; MacKay, D; Mears, A; Mildren, P; Mudher, A; Newman, TA; Shepherd, D; Squire, A | 1 |
| Chirita, CN; Kuret, J; Necula, M | 1 |
| Champy, P; Duyckaerts, C; Féger, J; Hirsch, EC; Höglinger, GU; Khondiker, ME; Lannuzel, A; Lombes, A; Medja, F; Michel, PP; Oertel, WH; Prigent, A; Ruberg, M | 1 |
| Biernat, J; Gazova, Z; Khlistunova, I; Mandelkow, E; Mandelkow, EM; Pickhardt, M; von Bergen, M; Wang, Y | 1 |
| Arnold, SE; Chatterjee, A; Clark, CM; Coslett, HB; Farmer, J; Forman, MS; Grossman, M; Hurtig, HI; Johnson, JK; Karlawish, JH; Lee, VM; Miller, BL; Rosen, HJ; Trojanowski, JQ; Van Deerlin, V | 1 |
| Coksezen, A; Khlistunova, I; Larbig, G; Mandelkow, E; Mandelkow, EM; Meyer, B; Pickhardt, M; Schmidt, B | 1 |
1 review(s) available for thiazoles and Tauopathies
| Article | Year |
|---|---|
Development of tau aggregation inhibitors for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Benzothiazoles; Databases, Factual; Humans; tau Proteins; Tauopathies; Thiazoles | 2009 |
28 other study(ies) available for thiazoles and Tauopathies
| Article | Year |
|---|---|
Increasing O-GlcNAcylation Attenuates tau Hyperphosphorylation and Behavioral Impairment in rTg4510 Tauopathy Mice.
Topics: Alzheimer Disease; Animals; Humans; Mice; Pyrans; Tauopathies; Thiazoles | 2023 |
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Topics: Aged; Alzheimer Disease; Aniline Compounds; Aphasia, Primary Progressive; Carbolines; Female; Frontotemporal Dementia; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; tau Proteins; Tauopathies; Thiazoles | 2019 |
Decreased meta-memory is associated with early tauopathy in cognitively unimpaired older adults.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain; Carbolines; Contrast Media; Female; Healthy Volunteers; Humans; Male; Memory, Episodic; Metacognition; Middle Aged; Positron-Emission Tomography; Semantics; tau Proteins; Tauopathies; Thiazoles | 2019 |
Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice.
Topics: Animals; beta-N-Acetylhexosaminidases; Mice; Mice, Transgenic; Protein Processing, Post-Translational; Pyrans; tau Proteins; Tauopathies; Thiazoles | 2017 |
Time course of Tau toxicity and pharmacologic prevention in a cell model of Tauopathy.
Topics: Calcium; Cell Death; Cells, Cultured; Cytoplasm; Dimerization; Dose-Response Relationship, Drug; Hydrazines; Mutation; Protein Aggregates; Reactive Oxygen Species; tau Proteins; Tauopathies; Thiazoles; Time Factors | 2017 |
Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain; Carbolines; Cognitive Dysfunction; Cross-Sectional Studies; Diagnostic Self Evaluation; Entorhinal Cortex; Female; Frontal Lobe; Humans; Male; Middle Aged; Neocortex; Parietal Lobe; Phenanthrolines; Positron-Emission Tomography; Radiopharmaceuticals; Surveys and Questionnaires; tau Proteins; Tauopathies; Temporal Lobe; Thiazoles | 2017 |
Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy.
Topics: Animals; beta-N-Acetylhexosaminidases; Brain; Disease Models, Animal; Disease Progression; Doxycycline; Enzyme Inhibitors; Gene Expression; Humans; Mice; Mice, 129 Strain; Mice, Transgenic; Motor Activity; Mutant Proteins; Neurofibrillary Tangles; Phosphorylation; Pyrans; Recombinant Proteins; tau Proteins; Tauopathies; Thiazoles | 2018 |
Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Cyclin-Dependent Kinase 5; Diamines; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Learning; Male; Memory; Mice; Mice, Transgenic; Neuroprotective Agents; Phosphorylation; Presenilin-1; Protein Kinase Inhibitors; tau Proteins; Tauopathies; Thiazoles; Treatment Outcome | 2013 |
Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls.
Topics: Age Factors; Aged; Alzheimer Disease; Aminopyridines; Amyloid beta-Peptides; Aniline Compounds; Animals; Autoradiography; Benzothiazoles; Brain; Brain Mapping; Calcium-Binding Proteins; Carbon Isotopes; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Middle Aged; Mutation; Positron-Emission Tomography; Protein Structure, Secondary; tau Proteins; Tauopathies; Thiazoles | 2013 |
Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy.
Topics: Acetylglucosamine; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Disease Models, Animal; Female; Glycosylation; Male; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Phosphorylation; Pyrans; tau Proteins; Tauopathies; Thiazoles | 2014 |
Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.
Topics: Analysis of Variance; Animals; beta-N-Acetylhexosaminidases; Blotting, Western; Brain; Female; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Transgenic; Nerve Tissue Proteins; Plethysmography; Pyrans; Respiratory Mechanics; tau Proteins; Tauopathies; Thiazoles | 2013 |
Binding of the PET radiotracer [¹⁸F]BF227 does not reflect the presence of alpha-synuclein aggregates in transgenic mice.
Topics: alpha-Synuclein; Animals; Benzoxazoles; Brain Stem; Disease Models, Animal; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Positron-Emission Tomography; Radioligand Assay; Tauopathies; Thalamus; Thiazoles | 2014 |
Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors.
Topics: Cell Line; Enzyme Inhibitors; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Phosphorylation; Protein Aggregation, Pathological; Pyrans; tau Proteins; Tauopathies; Thiazoles | 2015 |
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies.
Topics: Animals; Benzothiazoles; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorescent Dyes; High-Throughput Screening Assays; Humans; Mice; Microarray Analysis; Microscopy, Fluorescence; Molecular Structure; Neuroprotective Agents; Protein Aggregates; Protein Multimerization; tau Proteins; Tauopathies; Thiazoles | 2015 |
Heterogeneity in Suspected Non-Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Female; Humans; Longitudinal Studies; Male; Middle Aged; tau Proteins; Tauopathies; Thiazoles | 2016 |
Parcellation of human temporal polar cortex: a combined analysis of multiple cytoarchitectonic, chemoarchitectonic, and pathological markers.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Antigens, Nuclear; Benzothiazoles; Female; Histocytochemistry; Humans; Immunohistochemistry; Male; Nerve Tissue Proteins; Plant Lectins; Pyramidal Cells; Receptors, N-Acetylglucosamine; Tauopathies; Temporal Lobe; Thiazoles | 2009 |
Burden of neurodegenerative diseases in a cohort of medical examiner subjects.
Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Alzheimer Disease; Atrophy; Benzothiazoles; Brain; Brain Edema; Cohort Studies; Coroners and Medical Examiners; Female; Forensic Pathology; Frontotemporal Lobar Degeneration; Humans; Hygiene; Ill-Housed Persons; Immunohistochemistry; Male; Malnutrition; Middle Aged; Neurofibrillary Tangles; Neuropil Threads; Plaque, Amyloid; Staining and Labeling; Tauopathies; Thiazoles; Young Adult | 2010 |
Curcumin labeling of neuronal fibrillar tau inclusions in human brain samples.
Topics: Alzheimer Disease; Benzothiazoles; Brain Diseases; Curcumin; Humans; Neurofibrillary Tangles; Neurons; Pick Disease of the Brain; Silver Staining; Supranuclear Palsy, Progressive; tau Proteins; Tauopathies; Thiazoles | 2010 |
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity.
Topics: Animals; Animals, Genetically Modified; Axonal Transport; Blood-Brain Barrier; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Humans; Hydrazines; Methylene Blue; Mitochondria; Motor Neurons; Mutation; Neurons; Neuroprotective Agents; Phenotype; Phosphorylation; Protein Structure, Tertiary; Sensory Receptor Cells; tau Proteins; Tauopathies; Thiazoles; Vesicle-Associated Membrane Protein 1 | 2012 |
Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains.
Topics: Alzheimer Disease; Animals; Autoradiography; Benzothiazoles; Brain; Humans; Iodine Radioisotopes; Mice; Neurofibrillary Tangles; Positron-Emission Tomography; Radiopharmaceuticals; Recombinant Proteins; Rhodanine; Tauopathies; Thiazoles; Thiohydantoins; Tissue Distribution | 2011 |
Nitration of tau protein is linked to neurodegeneration in tauopathies.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Ganglia; Benzothiazoles; Cell Line; Cerebral Cortex; Down Syndrome; Female; Fluorescent Dyes; Humans; Male; Middle Aged; Nerve Degeneration; Neurodegenerative Diseases; Neurofibrillary Tangles; Nitrates; Pick Disease of the Brain; tau Proteins; Tauopathies; Thiazoles; Tissue Distribution | 2003 |
Proteasome inhibition stabilizes tau inclusions in oligodendroglial cells that occur after treatment with okadaic acid.
Topics: alpha-Crystallin B Chain; Benzothiazoles; Brain; Cell Line; Cysteine Endopeptidases; Cytoskeleton; Enzyme Inhibitors; Fluorescent Dyes; Humans; Immunohistochemistry; Inclusion Bodies; Leupeptins; Microtubules; Multienzyme Complexes; Okadaic Acid; Oligodendroglia; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Protein Phosphatase 2; tau Proteins; Tauopathies; Thiazoles | 2003 |
GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila.
Topics: Animals; Axonal Transport; Axons; Drosophila melanogaster; Drosophila Proteins; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Larva; Lithium Chloride; Locomotion; Phosphorylation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; tau Proteins; Tauopathies; Thiazoles; Urea | 2004 |
Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases.
Topics: Benzothiazoles; Binding, Competitive; Carbocyanines; Humans; Kinetics; Models, Chemical; Nerve Tissue Proteins; Protein Processing, Post-Translational; Solubility; tau Proteins; Tauopathies; Thiazoles | 2005 |
The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Behavior, Animal; Benzothiazoles; Body Weight; Caspase 3; Caspases; Cell Death; Cerebral Cortex; Cytarabine; Diagnostic Imaging; Dopamine and cAMP-Regulated Phosphoprotein 32; Doxorubicin; Dystonia; Electron Transport Complex III; Enzyme Activation; Glial Fibrillary Acidic Protein; Immunohistochemistry; Locomotion; Male; Microscopy, Electron, Transmission; Mitochondria; Neurons; Phosphopyruvate Hydratase; Phosphorylation; Posture; Psychomotor Performance; Rats; Rats, Inbred Lew; Rotenone; tau Proteins; Tauopathies; Thiazoles; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase; Ubiquitin; Uncoupling Agents | 2005 |
Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs.
Topics: Alzheimer Disease; Amino Acid Motifs; Benzothiazoles; Brain; Cell Line; Cell Line, Tumor; Centrifugation, Density Gradient; Chromatography; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Humans; Mass Spectrometry; Microscopy, Electron; Microscopy, Fluorescence; Models, Biological; Models, Chemical; Mutation; Neurons; Peptide Hydrolases; Phosphorylation; Plasmids; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; tau Proteins; Tauopathies; Thiazoles; Thrombin; Time Factors | 2006 |
Frontotemporal dementia: clinicopathological correlations.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Benzothiazoles; Brain; Dementia; Diagnosis, Differential; Female; Humans; Immunohistochemistry; Inclusion Bodies; Male; Middle Aged; Neurodegenerative Diseases; Neuropsychological Tests; Tauopathies; Thiazoles; Ubiquitin | 2006 |
Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of tau aggregation and toxicity in vitro and in cells.
Topics: Animals; Benzothiazoles; Binding Sites; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Humans; Hydrazines; Hydro-Lyases; Ligands; Models, Biological; Models, Chemical; Neurofibrillary Tangles; Protein Binding; Protein Denaturation; Protein Structure, Tertiary; tau Proteins; Tauopathies; Thiazoles | 2007 |