Page last updated: 2024-08-21

thiazoles and Squamous Cell Carcinoma of Head and Neck

thiazoles has been researched along with Squamous Cell Carcinoma of Head and Neck in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (75.00)24.3611
2020's4 (25.00)2.80

Authors

AuthorsStudies
Barbash, Z; Bauman, JE; Cho, J; Grandis, JR; Jin, N; Johnson, DE; Jura, N; Kang, H; Keam, B; Kim, HR; Kim, MO; Krogan, NJ; Lee, MJ; Li, H; Mills, GB; Ng, PK; Swaney, DL; Tarcic, G; Torosyan, H; VanLandingham, NK; Zeng, Y1
Bayley, A; Bratman, SV; Cho, J; Day, D; Giuliani, M; Hansen, AR; Hope, A; Jang, R; Karithanam, R; Kim, J; O'Sullivan, B; Prawira, A; Ringash, J; Siu, LL; Spreafico, A; Waldron, J; Weinreb, I1
Furukawa, K; Naruse, T; Okuyama, K; Omori, K; Tsuchihashi, H; Umeda, M; Yanamoto, S1
Ailles, L; Barrett, JW; Boutros, PC; Fung, K; Howlett, CJ; MacNeil, D; Meens, J; Mymryk, JS; Nichols, AC; Pinto, N; Plantinga, P; Ruicci, KM; Stecho, W; Yoo, J1
Baer-Dubowska, W; Kleszcz, R; Krajka-Kuźniak, V; Paluszczak, J1
Barrett, JW; Fung, K; Khan, MI; MacNeil, D; Mymryk, JS; Nichols, AC; Pinto, N; Ruicci, KM; Yoo, J1
Badarni, M; Balaban, N; Cohen, L; Dinur, AB; Elkabets, M; Grénman, R; Joshua, BZ; Prasad, M; Rotblat, B; Yegodayev, KM; Zorea, J1
Alvarado, D; Duvvuri, U; Godse, NR; Grandis, JR; Hedberg, ML; Kemp, C; Khan, NI; Kim, S; Kulkarni, S; LaVallee, T; Meister, KS1
Chen, CC; Huang, LY; Huang, WC; Lin, YC; Lin, YT; Wei, TT; Wu, MH1
Brockhoff, G; Doescher, J; Haug, A; Mißlbeck, M; Pickhard, A; Piontek, G; Reiter, R; Rudelius, M; Schiefler, C; Schuettler, D1
Fukuda, S; Inamura, N; Kimura, T; Nishihara, H; Tanaka, S; Tanino, M; Tsuda, M; Wang, L; Yanagi, H1
Dunn, EF; Iida, M; Li, C; Wheeler, DL1
Chinn, SB; Hochstim, C; Masood, R; Schorn, VJ; Sinha, UK; Zhu, S1
Knecht, R; Kurzweg, T; Laban, S; Möckelmann, N1
Bednash, JS; Chiosea, SI; Grandis, JR; Morariu, EM; Otte, CG; Seethala, RR; Wheeler, SE1
Ang, KK; Glisson, B; Johnson, FM; Milas, L; Molkentine, DP; Molkentine, JM; Raju, U; Riesterer, O; Wang, ZQ1

Reviews

1 review(s) available for thiazoles and Squamous Cell Carcinoma of Head and Neck

ArticleYear
Current treatment options for recurrent/metastatic head and neck cancer: a post-ASCO 2011 update and review of last year's literature.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2012, Volume: 269, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cetuximab; Combined Modality Therapy; Dasatinib; ErbB Receptors; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Indoles; Neoplasm Recurrence, Local; Palliative Care; Pyrimidines; Pyrroles; Quinazolines; Quinazolinones; Salvage Therapy; Squamous Cell Carcinoma of Head and Neck; Sunitinib; Thiazoles

2012

Trials

1 trial(s) available for thiazoles and Squamous Cell Carcinoma of Head and Neck

ArticleYear
Phase I trial of alpelisib in combination with concurrent cisplatin-based chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck.
    Oral oncology, 2020, Volume: 108

    Topics: Aged; Chemoradiotherapy; Cisplatin; Female; Humans; Middle Aged; Squamous Cell Carcinoma of Head and Neck; Thiazoles

2020

Other Studies

14 other study(ies) available for thiazoles and Squamous Cell Carcinoma of Head and Neck

ArticleYear
Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma.
    The Journal of clinical investigation, 2021, 11-15, Volume: 131, Issue:22

    Topics: Animals; Class I Phosphatidylinositol 3-Kinases; Head and Neck Neoplasms; Humans; Male; Mice; Middle Aged; Mutation; Protein Domains; Squamous Cell Carcinoma of Head and Neck; Thiazoles

2021
Selective inhibition of PI3K110α as a novel therapeutic strategy for cetuximab‑resistant oral squamous cell carcinoma.
    Oncology reports, 2020, Volume: 44, Issue:3

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cetuximab; Chemoradiotherapy, Adjuvant; Class I Phosphatidylinositol 3-Kinases; Drug Resistance, Neoplasm; Female; Humans; Male; Mice; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasm Invasiveness; Progression-Free Survival; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Thiazoles; Xenograft Model Antitumor Assays

2020
TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma.
    Journal of experimental & clinical cancer research : CR, 2020, Oct-15, Volume: 39, Issue:1

    Topics: Animals; Apoptosis; Axl Receptor Tyrosine Kinase; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; MAP Kinase Signaling System; Mice; Prognosis; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Squamous Cell Carcinoma of Head and Neck; Survival Rate; Thiazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
The inhibition of c-MYC transcription factor modulates the expression of glycolytic and glutaminolytic enzymes in FaDu hypopharyngeal carcinoma cells.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2018, Volume: 27, Issue:6

    Topics: Cell Line, Tumor; Cell Survival; Glutamine; Glycolysis; Humans; Hypopharyngeal Neoplasms; Proto-Oncogene Proteins c-myc; Squamous Cell Carcinoma of Head and Neck; Thiazoles

2018
ERK-TSC2 signalling in constitutively-active HRAS mutant HNSCC cells promotes resistance to PI3K inhibition.
    Oral oncology, 2018, Volume: 84

    Topics: Cell Cycle; Cell Line, Tumor; Drug Resistance, Neoplasm; Genes, ras; Head and Neck Neoplasms; Humans; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mechanistic Target of Rapamycin Complex 1; Molecular Targeted Therapy; Mutation, Missense; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Ribosomal Protein S6 Kinases; RNA Interference; Squamous Cell Carcinoma of Head and Neck; Thiazoles; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein

2018
Repression of AXL expression by AP-1/JNK blockage overcomes resistance to PI3Ka therapy.
    JCI insight, 2019, 03-12, Volume: 5

    Topics: Animals; Anthracenes; Antineoplastic Agents; Axl Receptor Tyrosine Kinase; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Esophageal Neoplasms; Head and Neck Neoplasms; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Squamous Cell Carcinoma of Head and Neck; Thiazoles; Tongue; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Xenograft Model Antitumor Assays

2019
HER3 targeting potentiates growth suppressive effects of the PI3K inhibitor BYL719 in pre-clinical models of head and neck squamous cell carcinoma.
    Scientific reports, 2019, 06-24, Volume: 9, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Mice; Molecular Targeted Therapy; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptor, ErbB-3; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Thiazoles; Up-Regulation; Xenograft Model Antitumor Assays

2019
Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress.
    Oncotarget, 2014, Jan-15, Volume: 5, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Growth Processes; Cell Line, Tumor; Dasatinib; Drug Synergism; Endoplasmic Reticulum Stress; Female; Head and Neck Neoplasms; Humans; Metformin; Mice; Mice, Nude; Pyrimidines; Squamous Cell Carcinoma of Head and Neck; Thiazoles; Xenograft Model Antitumor Assays

2014
Inhibition of SphK1 reduces radiation-induced migration and enhances sensitivity to cetuximab treatment by affecting the EGFR / SphK1 crosstalk.
    Oncotarget, 2014, Oct-30, Volume: 5, Issue:20

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cetuximab; Disease Progression; ErbB Receptors; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Paraffin Embedding; Phosphotransferases (Alcohol Group Acceptor); Receptor Cross-Talk; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Thiazoles

2014
Notch1 regulates invasion and metastasis of head and neck squamous cell carcinoma by inducing EMT through c-Myc.
    Auris, nasus, larynx, 2017, Volume: 44, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antigens, CD; Cadherins; Carcinogenesis; Carcinoma, Squamous Cell; Cell Enlargement; Cell Line, Tumor; Diamines; Epithelial-Mesenchymal Transition; Female; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Prognosis; Proto-Oncogene Proteins c-myc; Receptor, Notch1; Squamous Cell Carcinoma of Head and Neck; Thiazoles; Vimentin; Young Adult

2017
Dasatinib blocks cetuximab- and radiation-induced nuclear translocation of the epidermal growth factor receptor in head and neck squamous cell carcinoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; Dasatinib; ErbB Receptors; Head and Neck Neoplasms; Humans; Neoplasms, Squamous Cell; Protein Kinase Inhibitors; Protein Transport; Pyrimidines; Squamous Cell Carcinoma of Head and Neck; Thiazoles

2010
Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition.
    Head & neck, 2011, Volume: 33, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Carcinoma; Carcinoma, Squamous Cell; Disease Models, Animal; Enzyme Inhibitors; Head and Neck Neoplasms; Humans; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Squamous Cell; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Thiazoles; Treatment Outcome

2011
Lyn kinase mediates cell motility and tumor growth in EGFRvIII-expressing head and neck cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, May-15, Volume: 18, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; CSK Tyrosine-Protein Kinase; Dasatinib; Disease Progression; ErbB Receptors; Head and Neck Neoplasms; Humans; Immunoprecipitation; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-yes; Pyrimidines; Random Allocation; RNA Interference; RNA, Small Interfering; Squamous Cell Carcinoma of Head and Neck; src-Family Kinases; Thiazoles; Transplantation, Heterologous

2012
Dasatinib, a multi-kinase inhibitor increased radiation sensitivity by interfering with nuclear localization of epidermal growth factor receptor and by blocking DNA repair pathways.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 105, Issue:2

    Topics: Active Transport, Cell Nucleus; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Nucleus; CSK Tyrosine-Protein Kinase; Dasatinib; DNA Repair; ErbB Receptors; Focal Adhesion Protein-Tyrosine Kinases; Head and Neck Neoplasms; Humans; Protein Kinase Inhibitors; Pyrimidines; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; src-Family Kinases; Thiazoles

2012