Page last updated: 2024-08-21

thiazoles and Protein Aggregation, Pathological

thiazoles has been researched along with Protein Aggregation, Pathological in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's31 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dammers, C; Gremer, L; Lecher, J; Reiss, K; Schwarten, M; Stoldt, M; Willbold, D; Ziehm, T1
Aigbirhio, FI; Buell, AK; Fisher, E; Janik, M; Richardson, R; Tóth, G; Zhao, Y1
Bourgault, S; Nguyen, PT; Sebastiao, M; Zottig, X1
Gospodarczyk, W; Kozak, M1
Kumar, H; Kumari, P; Singh, J; Udgaonkar, JB1
Abdelhameed, AS; Khan, RH; Masroor, A; Neelofar, K; Nusrat, S; Siddqi, MK; Zaidi, N; Zaman, M1
Taniguchi, A1
da Silva, DC; Lima, LMTR1
Chung, YH; Hsu, PH; Lin, KJ; Lin, YT; Liu, HL; Yang, LY; Yen, TC1
Candeias, E; Cardoso, SM; Chand, K; Chaves, S; Rajeshwari, R; Santos, MA1
Milán-Garcés, EA; Puranik, M; Ramachandran, G; Udgaonkar, JB1
Almeida, B; Ashcroft, AE; Fraga, J; Macedo-Ribeiro, S; Radford, SE; Scarff, CA1
Cui, M; Dai, J; Jia, J; Liu, B1
Breydo, L; Morgan, D; Uversky, VN1
Chen, YX; Li, YM; Liu, Q; Qiu, T; Zhao, YF1
Di Carlo, MG; Foderà, V; Leone, M; Militello, V; Minicozzi, V; Morante, S; Vetri, V1
Girbal-Neuhauser, E; Marcato-Romain, CE; Randrianjatovo-Gbalou, I1
Haque, MM; Kim, YK; Lim, S; Nam, G; Rhim, H; Ryoo, N1
Liu, J; Liu, Z; Yin, F; Zhang, Y1
Gao, X; Huang, HL; Shi, S; Wang, L; Wang, LL; Yao, JL; Yao, TM1
Baekelandt, V; Debyser, Z; Deleersnijder, A; Gerard, M; Macchi, F; Michiels, A; Munck, S; Pottel, H; Van den Haute, C1
Ågren, H; Govindaraju, T; Kuang, G; Murugan, NA; Narayanaswamy, N; Rajasekhar, K1
Andersen, NH; Huggins, KN; Kapurniotu, A; Shu, I; Sivanesam, K; Tatarek-Nossol, M1
Carver, JA; Dalpadado, RC; Hall, D; Maat, H1
Chemuru, S; Kar, K; Kodali, R; Misra, P; Wetzel, R1
Fuchigami, T; Haratake, M; Masuda, N; Nakayama, M; Takiguchi, T; Yoshida, S1
Hinckley, SH; Kuret, J; Lin, L; Nanavaty, N1
Bickle, L; Hopwood, JJ; Karageorgos, L1
Hasegawa, M; Higuchi, M; Hisanaga, SI; Imura, S; Masuda-Suzukake, M; Ono, M; Shimozawa, A; Takahara, D; Tarutani, A; Yanai, K1
Carlisle, RE; Dickhout, JG; Upagupta, C1
Claessens, MM; Raussens, V; Segers-Nolten, I; Sidhu, A; Subramaniam, V1

Reviews

2 review(s) available for thiazoles and Protein Aggregation, Pathological

ArticleYear
[Amyloid-selective Photooxygenation toward Treatment for Amyloid Diseases].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Catalysis; Dinitrocresols; Drug Discovery; Humans; Oxidation-Reduction; Photochemical Processes; Protein Aggregation, Pathological; Protein Binding; Riboflavin; Thiazoles

2018
Aβ42 and Aβ40: similarities and differences.
    Journal of peptide science : an official publication of the European Peptide Society, 2015, Volume: 21, Issue:7

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Antibodies, Monoclonal; Brain Chemistry; Humans; Molecular Probes; Molecular Sequence Data; Peptide Fragments; Protein Aggregation, Pathological; Protein Structure, Secondary; Proteolysis; Styrenes; Thiazoles

2015

Other Studies

29 other study(ies) available for thiazoles and Protein Aggregation, Pathological

ArticleYear
Pyroglutamate-Modified Amyloid-β(3-42) Shows α-Helical Intermediates before Amyloid Formation.
    Biophysical journal, 2017, Apr-25, Volume: 112, Issue:8

    Topics: Amyloid; Amyloid beta-Peptides; Animals; Benzothiazoles; Circular Dichroism; Kinetics; Microscopy, Electron, Transmission; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Aggregation, Pathological; Protein Structure, Secondary; Recombinant Proteins; Solutions; Thiazoles; Trifluoroethanol; Water

2017
Detection and Characterization of Small Molecule Interactions with Fibrillar Protein Aggregates Using Microscale Thermophoresis.
    ACS chemical neuroscience, 2017, 09-20, Volume: 8, Issue:9

    Topics: alpha-Synuclein; Benzothiazoles; Binding, Competitive; Dose-Response Relationship, Drug; Drug Discovery; Humans; Indoles; Microscopy, Atomic Force; Optical Imaging; Protective Agents; Protein Aggregation, Pathological; Protein Binding; tau Proteins; Thermal Diffusion; Thiazoles

2017
Role of Site-Specific Asparagine Deamidation in Islet Amyloid Polypeptide Amyloidogenesis: Key Contributions of Residues 14 and 21.
    Biochemistry, 2017, 07-25, Volume: 56, Issue:29

    Topics: Amino Acid Substitution; Animals; Asparagine; Benzothiazoles; Cell Line, Tumor; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Mutation, Missense; Protein Aggregates; Protein Aggregation, Pathological; Rats; Thiazoles

2017
Microchip Circulation Drastically Accelerates Amyloid Aggregation of 1-42 β-amyloid Peptide from Felis catus.
    ACS chemical neuroscience, 2017, 11-15, Volume: 8, Issue:11

    Topics: Amyloid; Amyloid beta-Peptides; Animals; Benzothiazoles; Cats; Circular Dichroism; Drug Evaluation, Preclinical; Fluorometry; Lab-On-A-Chip Devices; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological; Protein Folding; Rheology; Scattering, Small Angle; Shear Strength; Surface-Active Agents; Thiazoles; X-Ray Diffraction

2017
Modulation of the extent of structural heterogeneity in α-synuclein fibrils by the small molecule thioflavin T.
    The Journal of biological chemistry, 2017, 10-13, Volume: 292, Issue:41

    Topics: alpha-Synuclein; Benzothiazoles; Humans; Multiprotein Complexes; Protein Aggregation, Pathological; Protein Multimerization; Thiazoles

2017
Deciphering the enhanced inhibitory, disaggregating and cytoprotective potential of promethazine towards amyloid fibrillation.
    International journal of biological macromolecules, 2018, Volume: 106

    Topics: Amyloid; Amyloidogenic Proteins; Amyloidosis; Anilino Naphthalenesulfonates; Benzothiazoles; Circular Dichroism; Dynamic Light Scattering; Fluorescence; Humans; Insulin; Muramidase; Parkinson Disease; Promethazine; Protein Aggregates; Protein Aggregation, Pathological; Thiazoles

2018
Physico-chemical properties of co-formulated fast-acting insulin with pramlintide.
    International journal of pharmaceutics, 2018, Aug-25, Volume: 547, Issue:1-2

    Topics: Benzothiazoles; Diabetes Mellitus; Drug Combinations; Drug Compounding; Drug Stability; Humans; Hypoglycemic Agents; Insulin Aspart; Insulin Lispro; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Protein Aggregation, Pathological; Spectrometry, Mass, Electrospray Ionization; Thiazoles

2018
Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction.
    Scientific reports, 2018, 08-27, Volume: 8, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Biomarkers; Blood-Brain Barrier; Brain; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Immunohistochemistry; Male; Mice; Mice, Transgenic; Plaque, Amyloid; Protein Aggregates; Protein Aggregation, Pathological; Protein Binding; Thiazoles; Ultrasonic Waves; Urea

2018
New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer's Disease.
    Molecules (Basel, Switzerland), 2019, Feb-07, Volume: 24, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Drug Design; Humans; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; Tacrine; Thiazoles

2019
Resonance Raman spectroscopic measurements delineate the structural changes that occur during tau fibril formation.
    Biochemistry, 2014, Oct-21, Volume: 53, Issue:41

    Topics: Amyloid; Benzothiazoles; Fluorescent Dyes; Heparin; Humans; Intrinsically Disordered Proteins; Kinetics; Microscopy, Atomic Force; Models, Molecular; Protein Aggregation, Pathological; Protein Conformation; Protein Interaction Domains and Motifs; Protein Stability; Protein Structure, Secondary; Recombinant Proteins; Repetitive Sequences, Amino Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; tau Proteins; Thiazoles

2014
Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion.
    Molecular & cellular proteomics : MCP, 2015, Volume: 14, Issue:5

    Topics: Ataxin-3; Benzothiazoles; Escherichia coli; Fluorescent Dyes; Gene Expression; Humans; Mass Spectrometry; Models, Molecular; Peptides; Protein Aggregates; Protein Aggregation, Pathological; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; Repressor Proteins; Spectrometry, Fluorescence; Thiazoles

2015
2-Phenylbenzothiazole conjugated with cyclopentadienyl tricarbonyl [CpM(CO)3] (M = Re, (99m)Tc) complexes as potential imaging probes for β-amyloid plaques.
    Dalton transactions (Cambridge, England : 2003), 2015, Apr-14, Volume: 44, Issue:14

    Topics: Amyloid beta-Peptides; Animals; Coordination Complexes; Isotope Labeling; Male; Mice; Molecular Imaging; Peptide Fragments; Protein Aggregation, Pathological; Rhenium; Technetium; Thiazoles

2015
Pseudocatalytic Antiaggregation Activity of Antibodies: Immunoglobulins can Influence α-Synuclein Aggregation at Substoichiometric Concentrations.
    Molecular neurobiology, 2016, Volume: 53, Issue:3

    Topics: alpha-Synuclein; Antibodies; Benzothiazoles; Biocatalysis; Biological Assay; Circular Dichroism; Fluorescence; Kinetics; Protein Aggregates; Protein Aggregation, Pathological; Thiazoles

2016
Thioflavin T templates amyloid β(1-40) conformation and aggregation pathway.
    Biophysical chemistry, 2015, Volume: 206

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Benzothiazoles; Fluorescence Recovery After Photobleaching; Fluorescent Dyes; Humans; Molecular Dynamics Simulation; Molecular Sequence Data; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological; Protein Conformation; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Thiazoles

2015
Quantification of amyloid fibrils using size exclusion chromatography coupled with online fluorescence and ultraviolet detection.
    Analytical biochemistry, 2015, Nov-01, Volume: 488

    Topics: Algorithms; Amyloid; Animals; Bacillus; Bacterial Proteins; Benzothiazoles; Biofilms; Calibration; Caseins; Cattle; Chromatography, Gel; Fluorescent Dyes; France; Models, Molecular; Molecular Weight; Protein Aggregates; Protein Aggregation, Pathological; Solubility; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiazoles

2015
Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors.
    International journal of molecular sciences, 2015, Aug-26, Volume: 16, Issue:9

    Topics: Cell Line; Enzyme Inhibitors; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Phosphorylation; Protein Aggregation, Pathological; Pyrans; tau Proteins; Tauopathies; Thiazoles

2015
A novel antagonistic role of natural compound icariin on neurotoxicity of amyloid β peptide.
    The Indian journal of medical research, 2015, Volume: 142, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Benzothiazoles; Cell Line; Cell Survival; Flavonoids; Humans; Hydrogen Peroxide; Microscopy, Electron, Transmission; Neurons; Peptide Fragments; Protein Aggregation, Pathological; Thiazoles

2015
Molecular "light switch" [Ru(phen)2dppzidzo](2+) monitoring the aggregation of tau.
    The Analyst, 2015, Nov-21, Volume: 140, Issue:22

    Topics: Alzheimer Disease; Benzothiazoles; Fluorescent Dyes; Humans; Light; Luminescent Agents; Luminescent Measurements; Models, Molecular; Organometallic Compounds; Protein Aggregates; Protein Aggregation, Pathological; tau Proteins; Thiazoles

2015
High-content analysis of α-synuclein aggregation and cell death in a cellular model of Parkinson's disease.
    Journal of neuroscience methods, 2016, Mar-01, Volume: 261

    Topics: alpha-Synuclein; Apoptosis; Benzothiazoles; Blotting, Western; Cell Count; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Genetic Vectors; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Indoles; Lentivirus; Microscopy, Fluorescence; Oxidative Stress; Parkinsonian Disorders; Protein Aggregation, Pathological; Protein Multimerization; Software; Thiazoles

2016
A High Affinity Red Fluorescence and Colorimetric Probe for Amyloid β Aggregates.
    Scientific reports, 2016, Apr-01, Volume: 6

    Topics: Absorption, Radiation; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Benzothiazoles; Colorimetry; Fluorescent Dyes; Fluorometry; Humans; Molecular Docking Simulation; Molecular Structure; Peptide Fragments; Protein Aggregation, Pathological; Thiazoles

2016
Peptide Inhibitors of the amyloidogenesis of IAPP: verification of the hairpin-binding geometry hypothesis.
    FEBS letters, 2016, Volume: 590, Issue:16

    Topics: Benzothiazoles; Circular Dichroism; Humans; Insulin; Islet Amyloid Polypeptide; Peptides; Protein Aggregation, Pathological; Protein Binding; Protein Conformation; Thiazoles

2016
Real-time monitoring of amyloid growth in a rigid gel matrix.
    Analytical biochemistry, 2016, 10-15, Volume: 511

    Topics: Amyloid; Animals; Benzothiazoles; Caseins; Gelatin; Gels; Humans; Kinetics; Protein Aggregation, Pathological; Thiazoles

2016
Rapid α-oligomer formation mediated by the Aβ C terminus initiates an amyloid assembly pathway.
    Nature communications, 2016, 08-22, Volume: 7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Circular Dichroism; Fluorescent Dyes; Humans; Peptide Fragments; Peptides; Protein Aggregation, Pathological; Protein Engineering; Protein Multimerization; Protein Structure, Secondary; Spectrum Analysis; Thiazoles; Time Factors

2016
Amyloid formation characteristics of GNNQQNY from yeast prion protein Sup35 and its seeding with heterogeneous polypeptides.
    Colloids and surfaces. B, Biointerfaces, 2017, Jan-01, Volume: 149

    Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Insulin; Mice; Mice, Transgenic; Muramidase; Peptide Termination Factors; Prion Proteins; Protein Aggregates; Protein Aggregation, Pathological; Protein Conformation, beta-Strand; Protein Folding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serum Albumin; Spectrometry, Fluorescence; Thiazoles

2017
Detection and Quantification Methods for Fibrillar Products of In Vitro Tau Aggregation Assays.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1523

    Topics: Alzheimer Disease; Animals; Benzothiazoles; Biological Assay; Humans; Microscopy, Electron; Protein Aggregation, Pathological; tau Proteins; Thiazoles

2017
Analysis of sheep α-synuclein provides a molecular strategy for the reduction of fibrillation.
    Biochimica et biophysica acta. Proteins and proteomics, 2017, Volume: 1865, Issue:3

    Topics: alpha-Synuclein; Amino Acid Sequence; Amyloid; Animals; Benzothiazoles; Humans; Hydrogen-Ion Concentration; Kinetics; Lewy Bodies; Mutation; Parkinson Disease; Protein Aggregation, Pathological; Sequence Alignment; Sheep; Solubility; Thiazoles

2017
Propagation of pathological α-synuclein in marmoset brain.
    Acta neuropathologica communications, 2017, Feb-02, Volume: 5, Issue:1

    Topics: alpha-Synuclein; Animals; Benzothiazoles; Brain; Callithrix; Female; Immunohistochemistry; Lewy Bodies; Microglia; Nerve Degeneration; Neurons; Parkinsonian Disorders; Protein Aggregation, Pathological; Recombinant Proteins; Sequence Homology, Amino Acid; Thiazoles; Tyrosine 3-Monooxygenase

2017
Analysis of the potency of various low molecular weight chemical chaperones to prevent protein aggregation.
    Biochemical and biophysical research communications, 2017, 04-22, Volume: 486, Issue:1

    Topics: Benzothiazoles; Cell Line; Docosahexaenoic Acids; Endoplasmic Reticulum Stress; Epithelial Cells; Glycerol; Humans; Kidney Tubules, Proximal; Molecular Weight; Phenylbutyrates; Protein Aggregates; Protein Aggregation, Pathological; Protein Folding; Staining and Labeling; Taurochenodeoxycholic Acid; Thapsigargin; Thiazoles; Trehalose; Unfolded Protein Response; Xenobiotics

2017
Distinct Mechanisms Determine α-Synuclein Fibril Morphology during Growth and Maturation.
    ACS chemical neuroscience, 2017, 03-15, Volume: 8, Issue:3

    Topics: alpha-Synuclein; Benzothiazoles; Circular Dichroism; Humans; Microscopy, Atomic Force; Multiprotein Complexes; Mutation; Protein Aggregation, Pathological; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles; Time Factors

2017