thiazoles has been researched along with Obesity in 278 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (2.52) | 18.7374 |
| 1990's | 73 (26.26) | 18.2507 |
| 2000's | 147 (52.88) | 29.6817 |
| 2010's | 44 (15.83) | 24.3611 |
| 2020's | 7 (2.52) | 2.80 |
| Authors | Studies |
|---|---|
| Abutaleb, NS; Elsebaei, MM; Hagras, M; Li, D; Mahgoub, AA; Mayhoub, AS; Mohammad, H; Seleem, MN | 1 |
| Chinetti, G; Le Garf, S; Le Menn, G; Mothe-Satney, I; Murdaca, J; Neels, JG; Rousseau, AS; Sibille, B | 1 |
| Chen, J; Confides, AL; Dupont-Versteegden, EE; El Khouli, RH; Finlin, BS; Johnson, ZR; Kern, PA; Memetimin, H; Morris, AJ; Sullivan, PG; Vekaria, HJ; Westgate, PM; Zhu, B | 2 |
| Aalkjaer, C; Chen, H; Simonsen, U | 1 |
| Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; Taratkin, M; Teijeira, Á; Tellew, JE; Thomas, AM; Thomas, SG; Thomson, SR; Tian, J; Tie, Y; Tirado, JL; Tolonen, A; Tosato, G; Tronnet, A; Tsai, S; Turtoi, A; Turtoi, E; Tvrdoňová, M; Tyagi, A; Tzou, DT; Uddin Ahmad, Z; Urias, E; Usawachintachit, M; Ustriyana, P; Utsumi, F; Vacca, M; Vaculovič, T; Vaidya, SS; Valentin, A; Valgepea, K; van den Berg, P; van den Bergh, JP; van der Heiden, K; van Gaalen, K; Van Gemert, W; van Haard, PMM; van Hest, JCM; Vecchiarelli, E; Večeřa, Z; Venkatesh, R; Verhaeghe, P; Verhagen, HJ; Vetter, JM; Vieira, D; Vilchez-Tschischke, JP; Villena-Gutierrez, R; Villoslada Terrones, V; Vital-Jacome, M; Voelkl, J; Vogel, K; Vogrin, S; Volke, D; von Bahr, V; Vysloužil, J; Wade, TL; Wagner-Gillespie, M; Walsh, SW; Wan, LJ; Wan, SP; Wang, AL; Wang, B; Wang, BY; Wang, C; Wang, D; Wang, F; Wang, H; Wang, HR; Wang, HY; Wang, J; Wang, JY; Wang, K; Wang, L; Wang, LF; Wang, P; Wang, Q; Wang, R; Wang, SF; Wang, SP; Wang, SR; Wang, T; Wang, W; Wang, WP; Wang, X; Wang, XJ; Wang, Y; Wang, YL; Wang, YN; Wáng, YXJ; Wang, Z; Wang, ZF; Wang, ZY; Waning, B; Warner, JM; Washington, SL; Watson, AK; Wei, B; Wei, C; Wei, F; Wei, X; Wei, Y; Wemhoff, AP; Wen, Z; Weng, TT; Wesdemiotis, C; Wheeler, DA; Wildner, M; Wilson, BK; Wirth, LJ; Wissler, M; Wu, F; Wu, G; Wu, J; Wu, KH; Wu, MC; Wu, P; Wu, PK; Wu, S; Wu, W; Wu, X; Wu, XP; Wu, Y; Wyatt, E; Wyllie, S; Xia, Y; Xiao, BH; Xiao, SZ; Xiao, W; Xiao, X; Xiao, Z; Xie, D; Xie, K; Xie, X; Xie, Y; Xie, YF; Xin, S; Xin, Z; Xing, Q; Xing, WQ; Xiong, D; Xiong, X; Xu, C; Xu, D; Xu, F; Xu, G; Xu, H; Xu, J; Xu, JY; Xu, L; Xu, N; Xu, W; Xu, X; Xu, Y; Xu, YM; Xue, H; Xue, J; Xue, Z; Yan, R; Yan, SQ; Yan, W; Yan, X; Yan, Z; Yang, C; Yang, D; Yang, F; Yang, FC; Yang, G; Yang, J; Yang, M; Yang, P; Yang, Q; Yang, R; Yang, S; Yang, SJ; Yang, TWW; Yang, X; Yang, Y; Yang, Z; Yao, C; Yao, L; Yao, LP; Yao, M; Yao, T; Yao, W; Yao, Y; Yaseen, T; Yazdani, V; Ye, J; Ye, S; Yerys, BE; Yi, HWL; Yi, JL; Yin, F; Yin, J; Yin, Y; Yin, Z; Yong, ZP; Yongli, S; Yoo, JS; Yoshikawa, N; You, Q; Yu, B; Yu, CQ; Yu, H; Yu, HG; Yu, J; Yu, L; Yu, Q; Yu, X; Yu, Y; Yu, YK; Yu, Z; Yuan, Q; Yuan, R; Yuan, W; Yuan, X; Yuan, Y; Zager, RA; Zagozdzon, A; Zaller, N; Zang, YP; Zappi, ME; Zelikoff, JT; Zeman, T; Zhai, X; Zhan, P; Zhang, B; Zhang, C; Zhang, G; Zhang, H; Zhang, HB; Zhang, J; Zhang, JS; Zhang, L; Zhang, M; Zhang, Q; Zhang, RX; Zhang, S; Zhang, T; Zhang, W; Zhang, WH; Zhang, X; Zhang, XX; Zhang, Y; Zhang, YQ; Zhang, YW; Zhang, Z; Zhang, ZH; Zhao, D; Zhao, FL; Zhao, K; Zhao, L; Zhao, M; Zhao, R; Zhao, S; Zhao, W; Zhao, WG; Zhao, X; Zhao, Y; Zheng, G; Zheng, J; Zheng, S; Zheng, W; Zheng, Y; Zheng, YG; Zhong, Z; Zhou, C; Zhou, D; Zhou, H; Zhou, HY; Zhou, L; Zhou, Q; Zhou, X; Zhou, Y; Zhou, YL; Zhou, Z; Zhu, J; Zhu, L; Zhu, N; Zhu, X; Zhu, XF; Zhu, Y; Zhu, Z | 1 |
| Chen, GZ; Fu, LL; Liang, G; Liu, Q; Lu, XY; Sun, CC; Zhang, XH; Zheng, XY | 1 |
| Boucher, J; Harms, M; Maurer, S | 1 |
| Bel, JS; Khaper, N; Lees, SJ; Tai, TC | 1 |
| Ding, G; Ding, N; Gao, H; He, W; Li, H; Sheng, J; Wang, J; Yu, J; Zha, J | 1 |
| Candelaria, PV; Daley-Brown, D; Gonzalez-Perez, RR; Lanier, V; Lee, R; Oprea-Iles, G; Pattillo, R; Quarshie, A; Vann, KT | 1 |
| Ham, SA; Han, DW; Han, SG; Hur, J; Hwang, JS; Hwang, SI; Lee, CH; Lee, WJ; Paek, KS; Park, JA; Seo, HG; Shin, HC; Yoo, T | 1 |
| Beyer-Westendorf, I; Beyer-Westendorf, J; Endig, S; Marten, S; Reitter, A; Tittl, L | 1 |
| Arco, R; Baixeras, E; Decara, J; Gavito, A; Lopez-Gambero, AJ; Martínez, A; Navarro, JA; Pavón, FJ; Rivera, P; Rodríguez de Fonseca, F; Serrano, A; Suárez, J; Tovar, R; Vargas, A | 1 |
| Alexander, CM; Confides, AL; Dupont-Versteegden, EE; Finlin, BS; Harfmann, B; Johnson, ZR; Jones, KA; Kasza, I; Kern, PA; Memetimin, H; Sullivan, PG; Vekaria, HJ; Westgate, PM; Zhu, B | 1 |
| Hotta, T; Iida, T; Imai, H; Inaba, T; Maeda, K; Mitani, I; Morinaga, H; Nakagawa, Y; Negoro, T; Ogoshi, Y; Oshida, S; Sakata, S; Sano, R; Tanaka, M; Ubukata, M | 1 |
| Antman, EM; Boriani, G; Braunwald, E; Giugliano, RP; Kuder, JF; Lanz, HJ; Mercuri, MF; Ruff, CT; Rutman, H; Shi, M | 1 |
| Abbasi, M; Hao, L; Khan, MSH; Scott, S; Wang, S; Wu, D; Yang, Y; Zhao, L; Zu, Y | 1 |
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| Bodkin, NL; Hansen, BC; Kliewer, SA; Lambert, MH; Lewis, MC; Oliver, WR; Plunket, KD; Russell, CS; Shenk, JL; Snaith, MR; Sternbach, DD; Sznaidman, ML; Willson, TM; Winegar, DA; Xu, HE | 1 |
| Fajardo, ME; Malacara, JM; Nava, LE | 1 |
| Asayama, K; Dobashi, K; Hayashibe, H; Kodera, K; Nakane, T; Nakazawa, S; Uchida, N | 1 |
| Buckingham, RE; Finegood, DT; Kojwang, D; Leonard, T; McArthur, MD; Thomas, MJ; Topp, BG | 1 |
| Jacinto, SM; Ljung, B; Oakes, ND; Thalén, PG | 1 |
| Maher, J | 1 |
| Brown, KK; Görgün, CZ; Harrington, WW; Hotamisligil, GS; Kliewer, SA; Oliver, WR; Tong, Q; Uysal, KT; Way, JM; Willson, TM | 1 |
| Buckingham, RE; Pickavance, LC; Wilding, JP | 1 |
| Castro Cabezas, M; Erkelens, DW; Halkes, CJ | 1 |
| Aljada, A; Dandona, P; Friedman, J; Garg, R; Ghanim, H; Mohanty, P | 1 |
| Aljada, A; Assian, E; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P | 1 |
| Bodkin, NL; Haney, J; Hansen, BC; Horikoshi, H; Ortmeyer, HK; Yoshioka, S | 1 |
| Burkey, BF; Chen, W; de Souza, CJ; Dong, M; Eckhardt, M; Gagen, K; Laurent, D | 1 |
| Atzpodien, E; Bedoucha, M; Boelsterli, UA | 1 |
| Akanuma, Y; Ide, T; Kadowaki, T; Kamon, J; Kimura, S; Komeda, K; Kubota, N; Miki, H; Motojima, K; Murakami, K; Nagai, R; Terauchi, Y; Tobe, K; Tsuchida, A; Waki, H; Yamauchi, T | 1 |
| Akanuma, Y; Ezaki, O; Fukayama, M; Hori, W; Ide, T; Itai, A; Kadowaki, T; Kagechika, H; Kamon, J; Kato, S; Kimura, S; Komeda, K; Kubota, N; Miki, H; Motojima, K; Murakami, K; Nagai, R; Shudo, K; Terauchi, Y; Tobe, K; Tsuboyama-Kasaoka, N; Tsuchida, A; Waki, H; Yamauchi, N; Yamauchi, T | 1 |
| Adler, A; Bush, E; Kramer, D; Rondinone, CM; Shapiro, R | 1 |
| Funakoshi, A; Hayashi, H; Ichikawa, M; Kanai, S; Miyasaka, K; Sato, Y | 1 |
| Brunmair, B; Fürnsinn, C; Gras, F; Nowotny, P; Roden, M; Vierhapper, H; Waldhäusl, W | 1 |
| Bedoucha, M; Boelsterli, UA | 1 |
| Kanai, H; Kurabayashi, M; Kuro-o, M; Nabeshima, Y; Nagai, R; Nakamura, T; Saito, Y; Sumino, H; Takeda, S; Yamagishi, T | 1 |
| Camejo, G; Ljung, B; Oakes, N | 1 |
| Marra, F; Pastacaldi, S | 1 |
| Montague, CT | 1 |
| McIntyre, RS | 1 |
| Buckingham, RE; Clarke, K; Cole, MA; Desrois, M; Draper, NJ; Sidell, RJ | 1 |
| Adachi, Y; Araki-Sasaki, R; Furuta, M; Gabazza, EC; Hori, Y; Katsuki, A; Nakatani, K; Sumida, Y; Tanaka, T; Yano, Y | 1 |
| Funakoshi, A; Ichikawa, M; Ichimaru, Y; Kanai, S; Kobayash, M; Miyasak, K; Ohta, M; Shimazoe, T; Watanabe, S; Yoshida, Y | 1 |
| Astrup, A; DeSmet, M; Gottesdiener, KM; Hul, GB; Saris, WH; Toubro, S; van Baak, MA | 1 |
| Ikeda, H; Odaka, H; Sugiyama, Y; Suzuki, M; Suzuki, N | 1 |
| Fukami, T; Fukuroda, T; Gomori, A; Hata, M; Hidaka, M; Ihara, M; Ishihara, A; Ishii, Y; Kanatani, A; Kanesaka, M; Kanno, T; Kobayashi, M; Mashiko, S; Murai, T; Okada, M; Sato, NA; Tanaka, T; Tominaga, Y; Watanabe, K | 1 |
| Legro, RS | 1 |
| Desouza, C; Dicker-Brown, A; Fonseca, V; Keebler, M; McNamara, DB; Murthy, SN; Poirier, LA | 1 |
| Arner, P; Dicker, A; Hauner, H; Lönnqvist, F; Näslund, E; Rydén, M; van Harmelen, V | 1 |
| Chun, D; Cobitz, AR; Davis, HM; Haimbach, RE; Jucker, BM; Mayer, M; McIntosh, TS; Ohlstein, DH; Sarkar, SK; Schaeffer, TR; Smith, SA | 1 |
| Akarca, C; Barton, DM; Baskar, V; Buch, HN; Kamalakannan, D; Singh, BM | 1 |
| Anderson, JW; Frederich, RC; Konz, EC; Reynolds, LR | 1 |
| Egawa, K; Iwanishi, M; Kobayashi, M; Shigeta, Y | 1 |
| Colca, JR; Edwards, CW; Hillman, RM; Hofmann, CA | 1 |
| Bowen, L; Shulman, GI; Stein, PP; Stevenson, R | 1 |
| Fujita, T; Ikeda, H; Shimura, Y; Sugiyama, Y; Taketomi, S | 1 |
| Belin, D; Bruzzone, R; Trimble, ER | 1 |
| Chang, AY; Wyse, BM | 1 |
| Diani, AR; Sawada, GA; Wyse, BM | 1 |
| Fujiwara, T; Horikoshi, H; Ushiyama, I; Yoshioka, S; Yoshioka, T | 1 |
| Kern, HF; Rausch, U; Trimble, ER | 1 |
48 review(s) available for thiazoles and Obesity
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
The colorful versatility of adipocytes: white-to-brown transdifferentiation and its therapeutic potential in humans.
Topics: Acetanilides; Adipocytes, Beige; Adipocytes, Brown; Adipocytes, White; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Cell Lineage; Cell Transdifferentiation; Diabetes Mellitus; Drugs, Investigational; Energy Metabolism; Humans; Imatinib Mesylate; Obesity; Roscovitine; Thermogenesis; Thiazoles | 2021 |
Mirabegron: The most promising adipose tissue beiging agent.
Topics: Acetanilides; Adipose Tissue; Adipose Tissue, White; Animals; Diabetes Mellitus, Type 2; Energy Metabolism; Humans; Obesity; Thiazoles | 2021 |
Dosing of Target-Specific Oral Anticoagulants in Special Populations.
Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Clinical Trials as Topic; Dabigatran; Humans; Kidney Diseases; Liver Diseases; Obesity; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Rivaroxaban; Thiazoles; Venous Thromboembolism | 2015 |
The use of atypical antipsychotics in pediatric bipolar disorder.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Attention Deficit and Disruptive Behavior Disorders; Bipolar Disorder; Child; Comorbidity; Dibenzothiazepines; Disorders of Excessive Somnolence; Humans; Obesity; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Thiazoles; Weight Gain | 2008 |
Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders.
Topics: Adolescent; Aggression; Antipsychotic Agents; Aripiprazole; Autistic Disorder; Benzodiazepines; Child; Child Development Disorders, Pervasive; Child, Preschool; Clozapine; Dibenzothiazepines; Disorders of Excessive Somnolence; Humans; Obesity; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Thiazoles | 2008 |
How can antipsychotics cause Diabetes Mellitus? Insights based on receptor-binding profiles, humoral factors and transporter proteins.
Topics: Adiponectin; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood Glucose; Clozapine; Diabetes Mellitus; Humans; Leptin; Obesity; Olanzapine; Piperazines; Quinolones; Receptor, Muscarinic M3; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Receptors, Histamine; Serotonin 5-HT1 Receptor Agonists; Thiazoles; Weight Gain | 2009 |
11beta-Hydroxysteroid dehydrogenase type 1 inhibitors: novel agents for the treatment of metabolic syndrome and obesity-related disorders?
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Enzyme Inhibitors; Humans; Metabolic Syndrome; Obesity; Sulfonamides; Thiazoles | 2013 |
Glitazones: clinical effects and molecular mechanisms.
Topics: Adipose Tissue; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Insulin resistance as the core defect in type 2 diabetes mellitus.
Topics: Adipose Tissue; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Obesity; Risk Factors; Thiazoles | 2002 |
[Mechanisms of thiazolidinedione derivatives for hypoglycemic and insulin sensitizing effects].
Topics: Animals; Arteriosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Lipid Metabolism; Obesity; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Management of rosiglitazone-induced edema: two case reports and a review of the literature.
Topics: Body Weight; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diuresis; Edema; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Middle Aged; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones | 2002 |
A truly deadly quartet: obesity, hypertension, hypertriglyceridemia, and hyperinsulinemia.
Topics: Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypoglycemic Agents; Hypolipidemic Agents; Male; Metabolic Syndrome; Metformin; Motor Activity; Obesity; Simvastatin; Thiazoles; Thiazolidinediones; Weight Loss | 2002 |
PPARgamma agonists in the treatment of type II diabetes: is increased fatness commensurate with long-term efficacy?
Topics: Animals; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2003 |
Rosiglitazone: potential beneficial impact on cardiovascular disease.
Topics: Albuminuria; Arteriosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hyperglycemia; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Insulin Resistance; Obesity; Risk Factors; Rosiglitazone; Thiazoles; Thiazolidinediones | 2003 |
Addition of rosiglitazone to metformin is most effective in obese, insulin-resistant patients with type 2 diabetes.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Male; Metformin; Middle Aged; Obesity; Randomized Controlled Trials as Topic; Rosiglitazone; Thiazoles; Thiazolidinediones | 2003 |
Current best treatment for non-alcoholic fatty liver disease.
Topics: Antioxidants; Chromans; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Fatty Liver; Gemfibrozil; Humans; Hypolipidemic Agents; Liver Transplantation; Obesity; Thiazoles; Thiazolidinediones; Troglitazone; Weight Loss | 2003 |
The relationship of obesity to the metabolic syndrome.
Topics: Adiponectin; Adipose Tissue; Blood Proteins; Body Constitution; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Metabolic Syndrome; Obesity; Proteins; Thiazoles; Thiazolidinediones | 2003 |
[Hypertension and insulin resistance in obese type 2 diabetic Wistar fatty rat].
Topics: Animals; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin Resistance; Obesity; Pioglitazone; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones | 2003 |
[Insulin-sensitizing agents: metformin and thiazolidinedione derivatives].
Topics: Adipocytes; Adiponectin; Cyclic AMP-Dependent Protein Kinases; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glycerol Kinase; Humans; Hypertension; Hypoglycemic Agents; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Metformin; Obesity; Proteins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2003 |
Prevention of type 2 diabetes.
Topics: Acarbose; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Exercise; Female; Humans; Hypoglycemic Agents; Male; Obesity; Risk Factors; Risk Reduction Behavior; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Ethnic disparities in type 2 diabetes: pathophysiology and implications for prevention and management.
Topics: Blood Circulation; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Genetic Predisposition to Disease; Humans; Hypoglycemic Agents; Incidence; Insulin; Life Style; Male; Metabolic Syndrome; Obesity; Prevalence; Risk Factors; Thiazoles; Thiazolidinediones; United States | 2003 |
Atypical antipsychotics and diabetes mellitus.
Topics: Antipsychotic Agents; Benzodiazepines; Diabetes Mellitus; Dibenzothiazepines; Glucose; Humans; Insulin Resistance; Islets of Langerhans; Obesity; Olanzapine; Pancreas; Piperazines; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles | 2004 |
[Psychotropics and weight gain].
Topics: Adolescent; Adult; Amisulpride; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Mass Index; Child; Clozapine; Dibenzothiazepines; Double-Blind Method; Female; Fructose; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Piperazines; Placebos; Psychotropic Drugs; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Socioeconomic Factors; Sulpiride; Thiazoles; Time Factors; Topiramate; Valproic Acid; Weight Gain | 2004 |
Roles of peroxisome proliferator-activated receptor delta (PPARdelta) in the control of fatty acid catabolism. A new target for the treatment of metabolic syndrome.
Topics: Adipose Tissue; Animals; Fatty Acids; Insulin Resistance; Ligands; Macaca mulatta; Metabolic Syndrome; Muscle, Skeletal; Obesity; PPAR delta; Thiazoles | 2004 |
Metabolic effects of the atypical antipsychotics.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Dyslipidemias; Glucose Metabolism Disorders; Humans; Insulin Resistance; Mental Disorders; Obesity; Olanzapine; Phenothiazines; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Thiazoles | 2007 |
Effects of troglitazone on insulin sensitivity.
Topics: Animals; Blood Glucose; Blood Pressure; Chromans; Diabetes Mellitus, Type 2; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 1996 |
[Steps toward the primary prevention of type II diabetes mellitus. Various epidemiological considerations].
Topics: Adult; Aged; Chromans; Comorbidity; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Diet, Reducing; Exercise; Female; Glucose Tolerance Test; Humans; Hypertension; Hypoglycemic Agents; Life Style; Male; Metformin; Middle Aged; National Institutes of Health (U.S.); Obesity; Prediabetic State; Risk Factors; Thiazoles; Thiazolidinediones; Troglitazone; United States | 1997 |
[Treatment of hypertension associated with diabetes mellitus].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cerebrovascular Disorders; Chromans; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Risk Factors; Thiazoles; Thiazolidinediones; Troglitazone | 1997 |
Novel pharmacological approaches to the prevention and treatment of non-insulin-dependent diabetes mellitus.
Topics: Animals; Diabetes Mellitus, Type 2; Humans; Nicotinic Acids; Obesity; Tetrahydronaphthalenes; Thiazoles | 1997 |
Insulin resistance syndrome: options for treatment.
Topics: Arteriosclerosis; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Microvascular Angina; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
[Thiazolidenediones, diabetes and adipogenesis].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transcription Factors | 1999 |
[Etiology and therapy of insulin resistance].
Topics: Animals; Arteriosclerosis; Biguanides; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Hypertension; Insulin Resistance; Life Style; Obesity; Risk Factors; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha | 1999 |
[Physiological function of peroxisome proliferator-activated receptor].
Topics: Animals; Blood Cells; Cell Differentiation; Cell Division; Colonic Neoplasms; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Ligands; Lipoprotein Lipase; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic | 1999 |
[Insulin resistance and cytokine, cytokine receptor].
Topics: Adipocytes; Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Obesity; Receptors, Tumor Necrosis Factor; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2000 |
[Obesity, insulin resistance and the implication of thiazolidinediones].
Topics: Adipose Tissue; Diabetes Mellitus; Fatty Acids, Nonesterified; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Pioglitazone; Receptor, Insulin; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2000 |
[Insulin sensitizer and urate metabolism].
Topics: Chromans; Diabetes Mellitus, Type 2; Female; Glucose; Gout; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Insulin Resistance; Male; Obesity; Syndrome; Thiazoles; Thiazolidinediones; Troglitazone; Uric Acid | 2000 |
[Hypoglycemic agents to improve insulin resistance].
Topics: Adipocytes; Animals; Cell Differentiation; Chromans; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Hyperglycemia; Hyperinsulinism; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Obesity; Pioglitazone; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists.
Topics: Animals; Chromans; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Islets of Langerhans; Mice; Mice, Knockout; Models, Biological; Mutation; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2000 |
[The importance of syndrome X in daily practice].
Topics: Anthropometry; Cardiovascular Diseases; Diet, Reducing; Exercise; Humans; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Lipoproteins, HDL; Lipoproteins, LDL; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones | 2000 |
Promising new approaches.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Obesity; Thiazoles; Weight Loss | 1999 |
The polycystic ovary syndrome: treatment with insulin sensitizing agents.
Topics: Chromans; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Obesity; Ovary; Polycystic Ovary Syndrome; Signal Transduction; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Peroxisome proliferator-activated receptor gamma, the ultimate liaison between fat and transcription.
Topics: Adipose Tissue; Cell Differentiation; Diabetes Mellitus, Type 2; Humans; Leptin; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha | 2000 |
Obesity and free fatty acids: double trouble.
Topics: Chylomicrons; Coronary Artery Disease; Fatty Acids, Nonesterified; Humans; Hyperglycemia; Hyperlipidemias; Insulin Resistance; Lipid Metabolism; Lipoproteins, VLDL; Liver; Obesity; Postprandial Period; Risk Factors; Thiazoles; Thiazolidinediones; Weight Loss | 2001 |
Toxicological consequences of altered peroxisome proliferator-activated receptor gamma (PPARgamma) expression in the liver: insights from models of obesity and type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Liver; Mice; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Pharmacological treatment of insulin resistance in obesity.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Rats; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2001 |
[Thiazolidinediones and PPARgamma system in repair of liver damage].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Arteriosclerosis; Chromans; Diabetes Mellitus, Type 2; Eicosanoids; Fatty Acids; Forecasting; Humans; Hypoglycemic Agents; In Vitro Techniques; Inflammation; Liver Cirrhosis; Neoplasms; Obesity; Receptors, Cytoplasmic and Nuclear; Research; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
Polycystic ovary syndrome. Long term sequelae and management.
Topics: Adult; Blood Glucose; Cardiovascular Diseases; Contraceptives, Oral; Diabetes Mellitus, Type 2; Diagnosis, Differential; Endometrial Neoplasms; Female; Humans; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Polycystic Ovary Syndrome; Pregnancy; Progestins; Randomized Controlled Trials as Topic; Risk Factors; Thiazoles; Thiazolidinediones | 2002 |
35 trial(s) available for thiazoles and Obesity
| Article | Year |
|---|---|
The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans.
Topics: Acetanilides; Adipocytes; Adipose Tissue, Beige; Adrenergic beta-3 Receptor Agonists; Adult; Aged; Biopsy; Blood Glucose; Female; Gene Expression Regulation; Humans; Male; Middle Aged; Muscle, Skeletal; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Thiazoles | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Impact of BMI on clinical outcomes of NOAC therapy in daily care - Results of the prospective Dresden NOAC Registry (NCT01588119).
Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Body Mass Index; Dabigatran; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Obesity; Prospective Studies; Pyrazoles; Pyridines; Pyridones; Registries; Rivaroxaban; Thiazoles; Thromboembolism; Treatment Outcome; Vitamin K | 2018 |
Human adipose beiging in response to cold and mirabegron.
Topics: Acetanilides; Adipose Tissue, Beige; Adrenergic beta-3 Receptor Agonists; Adult; Biopsy; Cold Temperature; Energy Metabolism; Female; Humans; Lipid Metabolism; Male; Membrane Proteins; Middle Aged; Obesity; Subcutaneous Fat; Thermogenesis; Thiazoles; Uncoupling Protein 1 | 2018 |
Relationship between body mass index and outcomes in patients with atrial fibrillation treated with edoxaban or warfarin in the ENGAGE AF-TIMI 48 trial.
Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Body Mass Index; Comorbidity; Embolism; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Obesity; Overweight; Proportional Hazards Models; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin | 2019 |
Changes in Visceral and Subcutaneous Fat in Youth With Type 2 Diabetes in the TODAY Study.
Topics: Adiposity; Adolescent; Blood Glucose; Body Fat Distribution; Child; Combined Modality Therapy; Diabetes Mellitus, Type 2; Drug Combinations; Exercise Therapy; Female; Humans; Insulin Resistance; Intra-Abdominal Fat; Life Style; Male; Metformin; Obesity; Sex Factors; Subcutaneous Fat; Thiazoles | 2019 |
Diabetes and gout: efficacy and safety of febuxostat and allopurinol.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Body Mass Index; Cohort Studies; Comorbidity; Diabetes Complications; Dose-Response Relationship, Drug; Enzyme Inhibitors; Febuxostat; Female; Gout; Gout Suppressants; Humans; Intention to Treat Analysis; Kidney; Lost to Follow-Up; Male; Middle Aged; Obesity; Patient Dropouts; Renal Insufficiency; Thiazoles; Xanthine Oxidase; Young Adult | 2013 |
Activation of human brown adipose tissue by a β3-adrenergic receptor agonist.
Topics: Acetanilides; Adipose Tissue, Brown; Adrenergic Agonists; Basal Metabolism; Chromatography, High Pressure Liquid; Fluorodeoxyglucose F18; Glucose; Humans; Male; Obesity; Positron-Emission Tomography; Receptors, Adrenergic, beta-3; Tandem Mass Spectrometry; Thiazoles; Tomography, X-Ray Computed; Young Adult | 2015 |
METFORMIN-SUSTAINED WEIGHT LOSS AND REDUCED ANDROID FAT TISSUE AT 12 MONTHS IN EMPOWIR (ENHANCE THE METABOLIC PROFILE OF WOMEN WITH INSULIN RESISTANCE): A DOUBLE BLIND, PLACEBO-CONTROLLED, RANDOMIZED TRIAL OF NORMOGLYCEMIC WOMEN WITH MIDLIFE WEIGHT GAIN.
Topics: Adipose Tissue; Adult; Aging; Body Fat Distribution; Climacteric; Double-Blind Method; Drug Combinations; Female; Humans; Insulin Resistance; Metformin; Middle Aged; Obesity; Overweight; Placebos; Thiazoles; Weight Gain; Weight Loss | 2016 |
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Comorbidity; Dose-Response Relationship, Drug; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperlipidemias; Hypertension; Hyperuricemia; Kidney Diseases; Male; Middle Aged; Obesity; Thiazoles; Treatment Outcome; United States; Uric Acid; Young Adult | 2010 |
Population pharmacokinetic/pharmacodynamic model of subcutaneous adipose 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) activity after oral administration of AMG 221, a selective 11β-HSD1 inhibitor.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Administration, Oral; Adult; Biomarkers, Pharmacological; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Male; Models, Biological; Obesity; Subcutaneous Fat, Abdominal; Thiazoles | 2011 |
Targeted reduction of advanced glycation improves renal function in obesity.
Topics: Adolescent; Adult; Animals; Cross-Over Studies; Diet; Glycation End Products, Advanced; Humans; Inflammation; Kidney; Kidney Diseases; Male; Mice; Mice, Knockout; Middle Aged; Obesity; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thiazoles; Young Adult | 2011 |
Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Cardiovascular Diseases; Comorbidity; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Illinois; Male; Metabolic Diseases; Middle Aged; Obesity; Retrospective Studies; Sex Factors; Thiazoles; Treatment Outcome; Uric Acid; Young Adult | 2012 |
Enhanced ziprasidone combination therapy effectiveness in obese compared to nonobese patients with bipolar disorder.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Longitudinal Studies; Male; Middle Aged; Obesity; Piperazines; Thiazoles; Treatment Outcome | 2012 |
Effect of a 28-d treatment with L-796568, a novel beta(3)-adrenergic receptor agonist, on energy expenditure and body composition in obese men.
Topics: Adrenergic beta-3 Receptor Agonists; Adult; Blood Glucose; Body Composition; Calorimetry, Indirect; Cholesterol; Diet; Double-Blind Method; Energy Metabolism; Fasting; Fatty Acids; Glucose Tolerance Test; Humans; Insulin; Kinetics; Male; Middle Aged; Obesity; Placebos; Sulfonamides; Thiazoles; Triglycerides | 2002 |
The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects.
Topics: Adiponectin; Adult; Animals; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Lipids; Male; Middle Aged; Obesity; Proteins; Rats; Thiazoles; Thiazolidinediones | 2002 |
Troglitazone therapy improves endothelial function to near normal levels in women with polycystic ovary syndrome.
Topics: Blood Glucose; Blood Pressure; Chromans; Endothelium, Vascular; Female; Humans; Hyperandrogenism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Obesity; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Regional Blood Flow; Testosterone; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilation | 2003 |
Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Adult; Aged; Biopsy; Chromans; Culture Media, Conditioned; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Metformin; Middle Aged; Molecular Weight; Obesity; Proteins; Thiazoles; Thiazolidinediones; Tissue Distribution; Troglitazone | 2003 |
Usefulness of troglitazone administration to obese hyperglycaemic patients with near-normoglycaemia.
Topics: Adult; Aged; Blood Glucose; Chromans; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 2003 |
Six-month, blinded, multicenter continuation study of ziprasidone versus olanzapine in schizophrenia.
Topics: Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Brief Psychiatric Rating Scale; Double-Blind Method; Drug Administration Schedule; Follow-Up Studies; Humans; Obesity; Olanzapine; Piperazines; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Thiazoles; Treatment Outcome; Weight Gain | 2005 |
Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men.
Topics: Adolescent; Adult; Apolipoproteins B; Cholesterol, HDL; Double-Blind Method; Fatty Acids; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Obesity; Oxidation-Reduction; Oxidative Stress; Placebos; PPAR delta; Thiazoles; Triglycerides | 2008 |
Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone.
Topics: Adult; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Lipids; Male; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 1994 |
Metabolic effects of darglitazone, an insulin sensitizer, in NIDDM subjects.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Fatty Acids, Nonesterified; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Obesity; Thiazoles; Thiazolidinediones | 1995 |
Leptin concentrations in the polycystic ovary syndrome.
Topics: Adult; Body Mass Index; Chromans; Double-Blind Method; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Obesity; Osmolar Concentration; Polycystic Ovary Syndrome; Proteins; Thiazoles; Thiazolidinediones; Troglitazone | 1997 |
Troglitazone decreases the proportion of small, dense LDL and increases the resistance of LDL to oxidation in obese subjects.
Topics: Adult; Blood Glucose; Body Weight; Cholesterol, LDL; Chromans; Cross-Over Studies; Double-Blind Method; Fasting; Female; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Peroxidation; Lipids; Male; Obesity; Oxidation-Reduction; Thiazoles; Thiazolidinediones; Troglitazone | 1998 |
Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance. Effects of troglitazone.
Topics: Acetylcholine; Adult; Analysis of Variance; Biomarkers; Blood Glucose; Cardiovascular System; Case-Control Studies; Chromans; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Fasting; Female; Forearm; Glucose Clamp Technique; Hemodynamics; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Nitroprusside; Obesity; omega-N-Methylarginine; Reference Values; Regional Blood Flow; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilation; Vasodilator Agents | 1998 |
The Diabetes Prevention Program. Design and methods for a clinical trial in the prevention of type 2 diabetes.
Topics: Adult; Aged; Blood Glucose; Cardiovascular Diseases; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Energy Intake; Exercise Therapy; Female; Glucose Tolerance Test; Health Policy; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Life Style; Liver; Male; Metformin; Middle Aged; Obesity; Outcome and Process Assessment, Health Care; Quality of Life; Research Design; Risk Factors; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Effect of troglitazone on lipoprotein(a) levels in obese subjects.
Topics: Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Humans; Hypoglycemic Agents; Insulin Resistance; Lipoprotein(a); Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Metabolic effects of troglitazone therapy in type 2 diabetic, obese, and lean normal subjects.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Efficacy of troglitazone on body fat distribution in type 2 diabetes.
Topics: Adipose Tissue; Body Mass Index; C-Peptide; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Middle Aged; Obesity; Sex Characteristics; Thiazoles; Thiazolidinediones; Tomography, X-Ray Computed; Troglitazone; Viscera; Weight Gain | 2000 |
Troglitazone prevents the rise in visceral adiposity and improves fatty liver associated with sulfonylurea therapy--a randomized controlled trial.
Topics: Adipose Tissue; Aged; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fatty Liver; Female; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Obesity; Pilot Projects; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
Gonadotropins at menopause: the influence of obesity, insulin resistance, and estrogens.
Topics: Chromans; Clomiphene; Estrogens; Feedback, Physiological; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Hypoglycemic Agents; Insulin Resistance; Menopause; Metformin; Middle Aged; Obesity; Pregnancy; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action?
Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Chemokine CCL2; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; I-kappa B Proteins; Insulin; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Male; Middle Aged; NADPH Oxidases; Neutrophils; NF-kappa B; Obesity; Phenylalanine; Phosphoproteins; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Tyrosine | 2001 |
Acute effect of L-796568, a novel beta 3-adrenergic receptor agonist, on energy expenditure in obese men.
Topics: Administration, Oral; Adolescent; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adult; Analysis of Variance; Anti-Obesity Agents; Cross-Over Studies; Energy Metabolism; Humans; Lipolysis; Middle Aged; Obesity; Sulfonamides; Thiazoles | 2002 |
Rosiglitazone amplifies the benefits of lifestyle intervention measures in long-standing type 2 diabetes mellitus.
Topics: Biomarkers; Blood Pressure; Body Constitution; Body Mass Index; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Life Style; Obesity; Placebos; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides; Weight Loss | 2002 |
196 other study(ies) available for thiazoles and Obesity
| Article | Year |
|---|---|
Phenylthiazoles with nitrogenous side chain: An approach to overcome molecular obesity.
Topics: Amines; Animals; Anti-Bacterial Agents; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Humans; Macrophages; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Molecular Structure; Obesity; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Structure-Activity Relationship; Thiazoles | 2019 |
Complementary Immunometabolic Effects of Exercise and PPARβ/δ Agonist in the Context of Diet-Induced Weight Loss in Obese Female Mice.
Topics: Animals; Diet, High-Fat; Energy Metabolism; Female; Glucose; Insulin Resistance; Lipid Metabolism; Lymphocyte Count; Mice; Mice, Obese; Muscle, Skeletal; Obesity; Physical Conditioning, Animal; PPAR delta; PPAR-beta; T-Lymphocytes, Regulatory; Thiazoles; Weight Loss | 2019 |
A sex-specific, COX-derived/thromboxane receptor activator causes depolarization and vasoconstriction in male mice mesenteric resistance arteries.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Hydrazines; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Mice; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Obesity; Piperazines; Receptors, Thromboxane; Sex Characteristics; Thiazoles; Vascular Resistance; Vasoconstriction; Vasodilation | 2020 |
Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy.
Topics: Animals; Anti-Inflammatory Agents; Cardiomyopathies; Diet, High-Fat; Dose-Response Relationship, Drug; Fibrosis; HEK293 Cells; Humans; Inflammation; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Myocardium; NF-kappa B; Obesity; Piperazines; Rats; Signal Transduction; Thiazoles; Toll-Like Receptor 4 | 2020 |
Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism.
Topics: Acetanilides; Adipose Tissue, Beige; Drug Synergism; Female; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Obesity; Pioglitazone; Thiazoles | 2021 |
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Diet, High-Fat; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Piperazines; Sulfonamides; Thiazoles | 2021 |
Type II Endometrial Cancer Overexpresses NILCO: A Preliminary Evaluation.
Topics: Adenocarcinoma, Papillary; Aged; Antibodies; Asian People; Black People; Carcinoma, Endometrioid; Cell Line, Tumor; Cell Proliferation; Cystadenocarcinoma, Serous; Diamines; Disease Progression; Endometrial Neoplasms; Endometrium; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Leptin; Middle Aged; Neoplasm Staging; Obesity; Protein Isoforms; Receptor, Notch1; Signal Transduction; Thiazoles | 2017 |
Ligand-Dependent Interaction of PPARδ With T-Cell Protein Tyrosine Phosphatase 45 Enhances Insulin Signaling.
Topics: Active Transport, Cell Nucleus; Adipocytes, White; Alternative Splicing; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cells, Cultured; Glucose Intolerance; Hepatocytes; Humans; Insulin Resistance; Male; Mice, Inbred ICR; Muscle Fibers, Skeletal; Obesity; PPAR delta; Protein Multimerization; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Recombinant Fusion Proteins; RNA Interference; Specific Pathogen-Free Organisms; Thiazoles | 2018 |
The adiponectin promoter activator NP-1 induces high levels of circulating TNFα and weight loss in obese (fa/fa) Zucker rats.
Topics: Adiponectin; Adipose Tissue, Brown; Animals; Body Weight; DNA (Cytosine-5-)-Methyltransferase 1; Dyslipidemias; Feeding Behavior; Gene Expression Regulation; Hypothalamus; Liver; Male; Obesity; Promoter Regions, Genetic; Rats; Rats, Zucker; Thiazoles; Thinness; Tumor Necrosis Factor-alpha; Weight Loss | 2018 |
Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity.
Topics: Acetic Acid; Animals; Diabetes Mellitus; Drug Discovery; Enzyme Inhibitors; Fatty Liver; Liver; Male; Mice, Inbred C57BL; Obesity; Rats; Rats, Sprague-Dawley; Stearoyl-CoA Desaturase; Thiazoles | 2018 |
Beneficial Metabolic Effects of Mirabegron In Vitro and in High-Fat Diet-Induced Obese Mice.
Topics: 3T3-L1 Cells; Acetanilides; Adipocytes; Adipocytes, Brown; Animals; Body Weight; Diet, High-Fat; Gene Expression Regulation; Glucose; Homeostasis; Male; Mice; Mice, Obese; Obesity; Thiazoles; Uncoupling Protein 1 | 2019 |
The evolving obesity paradigm story: from heart failure to atrial fibrillation.
Topics: Atrial Fibrillation; Body Mass Index; Heart Failure; Humans; Obesity; Pyridines; Thiazoles; Warfarin | 2019 |
Elevated
Topics: Acetyl-CoA Carboxylase; Acylation; Adult; Aged; Aged, 80 and over; Animals; CD4-Positive T-Lymphocytes; Cytokines; Fatty Acids; Female; Humans; Interleukin-17; Lipidomics; Male; Mice; Mice, Inbred C57BL; Middle Aged; Nuclear Receptor Subfamily 1, Group F, Member 3; Obesity; Promoter Regions, Genetic; Protein Binding; Pyrans; Th17 Cells; Thiazoles; Transcriptional Activation | 2019 |
Adipose tissue macrophage-derived exosomal miR-29a regulates obesity-associated insulin resistance.
Topics: Adipocytes; Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Exosomes; Gene Knockdown Techniques; Hepatocytes; In Vitro Techniques; Insulin Resistance; Macrophages; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle Cells; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles | 2019 |
Urogynecology digest : presented by Fiona M. Lindo.
Topics: Acetanilides; Bariatric Surgery; Cystitis, Interstitial; Female; Gynecology; Humans; Muscarinic Antagonists; Obesity; Pelvic Floor Disorders; Thiazoles; Urinary Bladder, Overactive; Urology | 2014 |
Correlated increase of omentin-1 and adiponectin by exenatide, avandamet and dietary change in diet-induced obese rats.
Topics: Adiponectin; Animals; Cytokines; Drug Combinations; Exenatide; Metformin; Obesity; Peptides; Rats; Thiazoles; Venoms | 2013 |
Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.
Topics: Acetyltransferases; Animals; Endoplasmic Reticulum Stress; Fatty Acid Elongases; Hep G2 Cells; Hepatocytes; Humans; Lipase; Liver; Male; Mice; Obesity; PPAR-beta; Thiazoles; Triglycerides | 2014 |
Pharmacological effects of JTT-551, a novel protein tyrosine phosphatase 1B inhibitor, in diet-induced obesity mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glycine; Hypothalamus; Leptin; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Signal Transduction; STAT3 Transcription Factor; Thiazoles | 2014 |
SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes.
Topics: Angiopoietin-Like Protein 8; Angiopoietin-like Proteins; Anilides; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Hepatocytes; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Mice, Mutant Strains; Obesity; Peptide Hormones; Signal Transduction; Sirtuin 1; Thiazoles; Time Factors; Torpor | 2015 |
Characteristics and management of gout patients in Europe: data from a large cohort of patients.
Topics: Adult; Allopurinol; Cohort Studies; Comorbidity; Cross-Sectional Studies; Europe; Febuxostat; Female; France; Gout; Gout Suppressants; Greece; Humans; Male; Middle Aged; Obesity; Patient Compliance; Thiazoles; Uric Acid | 2015 |
Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors.
Topics: ADP-ribosyl Cyclase 1; Animals; Cell Line; Dogs; Drug Discovery; Humans; Liver; Mice, Inbred C57BL; Molecular Docking Simulation; Muscles; NAD; Obesity; Quinolones; Thiazoles | 2015 |
Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.
Topics: Amides; Animals; Calcium; Cell Survival; Cytoprotection; Diet; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Energy Metabolism; Genes, Reporter; Glucose; HEK293 Cells; High-Throughput Screening Assays; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Luciferases; Metabolome; Mice, Obese; Molecular Chaperones; Obesity; Phenotype; Protein Folding; Thiazoles; Unfolded Protein Response; Weight Loss | 2015 |
Chronic peroxisome proliferator-activated receptorβ/δ agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity.
Topics: Adiponectin; Adipose Tissue; Animals; Aorta; Blood Glucose; Caveolin 1; Diet, High-Fat; Endothelium, Vascular; Glucose Tolerance Test; Hypertension; Insulin Resistance; Interleukin-6; Male; Mice; Nitric Oxide Synthase Type III; Obesity; PPAR delta; PPAR-beta; Reactive Oxygen Species; Sulfones; Thiazoles; Thiophenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Vasodilation | 2015 |
Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats.
Topics: Animals; Aorta, Abdominal; Collagen; Diabetes Mellitus; Glycation End Products, Advanced; Graft Occlusion, Vascular; Male; Neointima; Obesity; Rats; Rats, Zucker; Receptor for Advanced Glycation End Products; Shear Strength; Stents; Stress, Mechanical; Thiazoles; Transforming Growth Factor beta; Vascular Resistance | 2015 |
Retinoic acid receptor β2 agonists restore glycaemic control in diabetes and reduce steatosis.
Topics: Animals; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diet, High-Fat; Drugs, Investigational; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Kidney; Lipid Peroxidation; Liver; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Skeletal; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Pancreas; Receptors, Retinoic Acid; Thiazoles | 2016 |
Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Animals; Body Weight; Carbachol; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle Contraction; Muscle, Smooth; Obesity; Thiazoles; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2017 |
PI3Kα inhibition reduces obesity in mice.
Topics: Animals; Body Weight; Energy Metabolism; Male; Mice; Obesity; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Thiazoles; Treatment Outcome | 2016 |
Cannabinoid CB1 receptor antagonists in therapeutic and structural perspectives.
Topics: Animals; Anti-Obesity Agents; CHO Cells; Cricetinae; Cricetulus; Humans; Imidazoles; Isomerism; Models, Chemical; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Solubility; Structure-Activity Relationship; Thiazoles; Triazoles; Water | 2008 |
Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice.
Topics: Animals; Cell Line, Tumor; Diabetes Complications; Diabetes Mellitus; Hepatocytes; Humans; Lipogenesis; Liver; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Peroxisome Proliferators; PPAR delta; Response Elements; RNA, Small Interfering; Sterol Regulatory Element Binding Protein 1; Thiazoles; Transfection | 2008 |
2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity.
Topics: Animals; Anti-Obesity Agents; Benzodiazepines; Chemokines, CC; Humans; Indoles; Methylamines; Mice; Obesity; Piperazine; Piperazines; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Thiazoles | 2008 |
Synergistic interaction between neuropeptide Y1 and Y5 receptor pathways in regulation of energy homeostasis.
Topics: Animals; Anti-Obesity Agents; Body Weight; Dietary Fats; Drug Synergism; Eating; Energy Metabolism; Homeostasis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Obesity; Pyridines; Receptors, Neuropeptide Y; Spiro Compounds; Thiazoles | 2009 |
Modulation of nutrient sensing nuclear hormone receptors promotes weight loss through appetite suppression in mice.
Topics: Animals; Appetite Depressants; Appetite Regulation; Energy Metabolism; Insulin Resistance; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; PPAR alpha; PPAR delta; PPAR gamma; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Loss | 2010 |
Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities.
Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Carboxy-Lyases; Diabetes Mellitus, Type 2; Drug Design; Eating; Humans; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Obesity; Propanols; Thiazoles | 2010 |
Adipose tissue-targeted 11β-hydroxysteroid dehydrogenase type 1 inhibitor protects against diet-induced obesity.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipocytes; Adiponectin; Adipose Tissue; Animals; Body Weight; Dietary Fats; Disease Models, Animal; Enzyme Inhibitors; Glucose Intolerance; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Nicotinamide Phosphoribosyltransferase; Obesity; Piperazines; Sulfonamides; Thiazoles | 2011 |
Open adjunctive ziprasidone associated with weight loss in obese and overweight bipolar disorder patients.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Bipolar Disorder; Blood Glucose; Body Mass Index; Dose-Response Relationship, Drug; Fasting; Female; Humans; Male; Middle Aged; Obesity; Overweight; Piperazines; Prospective Studies; Thiazoles; Waist Circumference; Weight Loss | 2011 |
BVT.2733, a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, attenuates obesity and inflammation in diet-induced obese mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3-L1 Cells; Adipose Tissue; Animals; Body Weight; Chemokine CCL2; Diet; Enzyme Inhibitors; Glucocorticoids; Inflammation; Inflammation Mediators; Insulin Resistance; Macrophages; Male; Mice; Obesity; Piperazines; Sulfonamides; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
Anti-obesity effects of 3-hydroxychromone derivative, a novel small-molecule inhibitor of glycogen synthase kinase-3.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adiposity; Aminophenols; Animals; Anti-Obesity Agents; beta Catenin; Body Weight; Cell Differentiation; Chromones; Glycogen Synthase Kinase 3; HEK293 Cells; Hep G2 Cells; Humans; Lipid Metabolism; Lithium Chloride; Male; Maleimides; Mice; Mice, Inbred C57BL; Obesity; Protein Stability; Thiazoles | 2013 |
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.
Topics: Adipose Tissue; Animals; Fatty Acids, Nonesterified; Female; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Decreases in serum uric acid by amelioration of insulin resistance in overweight hypertensive patients: effect of a low-energy diet and an insulin-sensitizing agent.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Pressure; Body Weight; Caloric Restriction; Chromans; Data Interpretation, Statistical; Female; Glucose Tolerance Test; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Thiazoles; Thiazolidinediones; Troglitazone; Uric Acid | 2002 |
Expression of resistin in the adipose tissue is modulated by various factors including peroxisome proliferator-activated receptor alpha.
Topics: Adipose Tissue; Animals; Blotting, Northern; Gene Expression; Hormones, Ectopic; Intercellular Signaling Peptides and Proteins; Mice; Nerve Growth Factor; Obesity; Proteins; Receptors, Cytoplasmic and Nuclear; Resistin; RNA, Messenger; Thiazoles; Transcription Factors | 2002 |
Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study.
Topics: Adipocytes; Animals; Diabetes Mellitus; Dipeptidyl Peptidase 4; Drug Administration Schedule; Enzyme Inhibitors; Glucose Clamp Technique; Glucose Tolerance Test; Insulin; Lipolysis; Liver; Obesity; Pentanoic Acids; Rats; Rats, Zucker; Thiazoles; Thiazolidines | 2002 |
Seeking sweet relief for diabetes.
Topics: Behavior Control; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diet; Exercise; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Metformin; Obesity; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Treatment Outcome; United States | 2002 |
Troglitazone ameliorates abnormal activity of protein tyrosine phosphatase in adipose tissues of Otsuka Long-Evans Tokushima Fatty rats.
Topics: Adipose Tissue; Animals; Cell Fractionation; Chromans; Diabetes Mellitus; Disease Models, Animal; Hypoglycemic Agents; Insulin Resistance; Male; Obesity; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats.
Topics: Animals; Benzazepines; Binding, Competitive; Blood Glucose; Blood Pressure; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Glucose; Hyperinsulinism; Hypoglycemic Agents; Insulin; Kidney; Kidney Tubules, Proximal; Male; Obesity; Rats; Rats, Zucker; Receptors, Dopamine D1; Rosiglitazone; Sodium-Potassium-Exchanging ATPase; Thiazoles; Thiazolidinediones | 2002 |
Adipose tissue sensitization to insulin induced by troglitazone and MEDICA 16 in obese Zucker rats in vivo.
Topics: Adipose Tissue; Animals; Chromans; Esterification; Fasting; Fatty Acids, Nonesterified; Glycerol; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Lipolysis; Male; Obesity; Palmitic Acids; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Troglitazone | 2003 |
Altered renal microvascular response in Zucker obese rats.
Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Chromans; Hydronephrosis; In Vitro Techniques; Insulin; Microcirculation; Norepinephrine; Obesity; Rats; Rats, Zucker; Reference Values; Renal Artery; Renal Circulation; Thiazoles; Thiazolidinediones; Troglitazone; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2002 |
[News on diabetes and public health perspectives].
Topics: Administration, Oral; Adult; Chromans; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Exercise; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Obesity; Pancreas Transplantation; Patient Education as Topic; Pregnancy; Public Health; Risk Factors; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone | 2002 |
Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty rats.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Insulin Resistance; Lipid Metabolism; Liver; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Obesity; Organ Size; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 2003 |
Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation.
Topics: Adipocytes; Animals; Blood Vessels; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Diet; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Matrix Metalloproteinases, Membrane-Associated; Matrix Metalloproteinases, Secreted; Metalloendopeptidases; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Obese; Mitosis; Obesity; Phenylalanine; Protease Inhibitors; RNA, Messenger; Rosiglitazone; Stromal Cells; Thiazoles; Thiazolidinediones; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-3 | 2003 |
Pharmacologic treatment of type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Exenatide; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Insulin; Insulin Secretion; Monosaccharide Transport Proteins; Obesity; Peptide Fragments; Peptide Hormones; Peptides; Peroxisome Proliferators; Protein Precursors; Receptors, Cell Surface; Thiazoles; Venoms | 2003 |
Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency.
Topics: Aging; Animals; Aromatase; Bezafibrate; Blood Glucose; Cholesterol; Estradiol; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Models, Animal; Obesity; Pioglitazone; Testosterone; Thiazoles; Thiazolidinediones; Triglycerides | 2003 |
On the role of liver X receptors in lipid accumulation in adipocytes.
Topics: Adipocytes; Adipose Tissue; Animals; Anticholesteremic Agents; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Desmosterol; DNA-Binding Proteins; Fatty Acid Synthases; Female; Gene Expression Regulation; Humans; Hydrocarbons, Fluorinated; Lipid Metabolism; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Orphan Nuclear Receptors; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Sterol Regulatory Element Binding Protein 1; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Up-Regulation | 2003 |
Reduction of intramyocellular lipid following short-term rosiglitazone treatment in Zucker fatty rats: an in vivo nuclear magnetic resonance study.
Topics: Animals; Blood Glucose; Insulin; Lipid Metabolism; Lipids; Magnetic Resonance Spectroscopy; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides; Weight Gain | 2003 |
[Therapy decision based on the glucose triad. Drug treatment of type 2 diabetes].
Topics: 1-Deoxynojirimycin; Acarbose; Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Glucosamine; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin Resistance; Insulin Secretion; Metformin; Obesity; Pioglitazone; Risk Factors; Rosiglitazone; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Time Factors | 2003 |
[When HbA1c cannot be pushed down under 7. Don't hesitate to use a 2d antidiabetic agent].
Topics: Diabetes Mellitus; Drug Therapy, Combination; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones | 2003 |
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Body Weight; Dietary Fats; Energy Metabolism; Fatty Acids; Food, Formulated; Genetic Vectors; Lipid Metabolism; Mice; Mice, Knockout; Mice, Transgenic; Obesity; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Leptin; Recombinant Fusion Proteins; Thiazoles; Transcription Factors; Transgenes; Triglycerides | 2003 |
Rapid reversal of hepatic steatosis, and reduction of muscle triglyceride, by rosiglitazone: MRI/S studies in Zucker fatty rats.
Topics: Animals; Fatty Liver; Hepatomegaly; Hypoglycemic Agents; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides | 2003 |
Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis.
Topics: Adipose Tissue; Animals; Biomarkers; Blood Glucose; Eating; Energy Metabolism; Fenofibrate; Gene Expression; Glucose Tolerance Test; Glycated Hemoglobin; Homeostasis; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Lipids; Liver; Male; Obesity; Organ Size; Oxazines; Phenylpropionates; Pioglitazone; Rats; Rats, Mutant Strains; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Weight Gain | 2003 |
Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation.
Topics: Adipose Tissue; Animals; Basal Metabolism; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids; Fenofibrate; Glycogen; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Islets of Langerhans; Male; Muscle, Skeletal; Obesity; Rats; Rats, Inbred OLETF; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Viscera | 2003 |
Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Glucose Clamp Technique; Glucose Tolerance Test; Hyperglycemia; Hyperinsulinism; Insulin; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Piperazines; RNA, Messenger; Sulfonamides; Thiazoles | 2003 |
Use of perospirone for obesity and diabetes mellitus in patients with schizophrenia: three case reports.
Topics: Adult; Antipsychotic Agents; Diabetes Mellitus, Type 2; Humans; Indoles; Isoindoles; Male; Middle Aged; Obesity; Schizophrenia; Thiazoles; Weight Gain | 2004 |
Tourette syndrome: efficient treatment with ziprasidone and normalization of body weight in a patient with excessive weight gain under tiapride.
Topics: Adult; Antipsychotic Agents; Body Weight; Female; Humans; Obesity; Piperazines; Thiazoles; Tiapamil Hydrochloride; Tourette Syndrome; Weight Gain | 2004 |
Metabotropic glutamate receptor mGlu5 is a mediator of appetite and energy balance in rats and mice.
Topics: Animals; Appetite; Appetite Depressants; Dietary Fats; Eating; Energy Metabolism; Fenfluramine; Food Deprivation; Male; Mice; Mice, Knockout; Obesity; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Thiazoles; Weight Gain | 2005 |
Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Drinking; Drug Therapy, Combination; Drug Tolerance; Eating; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Obesity; Pentanoic Acids; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Time Factors | 2005 |
Antipsychotic drug-induced weight gain: development of an animal model.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Body Constitution; Body Weight; Dibenzothiazepines; Eating; Male; Mice; Mice, Inbred C57BL; Models, Animal; Obesity; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Thiazoles | 2005 |
Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats.
Topics: Animals; Body Weight; Butyrates; CD36 Antigens; Cholesterol; Coenzyme A Ligases; Eating; Endocannabinoids; Fatty Acid-Binding Proteins; Hepatocytes; Hyperlipidemias; Ion Channels; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Obesity; Oleic Acids; Phenylurea Compounds; PPAR alpha; Pyrimidines; Rats; Rats, Inbred WF; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones; Triglycerides; Uncoupling Protein 2 | 2005 |
LY226936 administered orally and centrally to obese Zucker rats suppresses food intake and body weight gain.
Topics: Administration, Oral; Animals; Appetite Depressants; Dose-Response Relationship, Drug; Eating; Female; Injections, Intraventricular; Male; Obesity; Random Allocation; Rats; Rats, Zucker; Specific Pathogen-Free Organisms; Thiazoles; Weight Gain | 1994 |
Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Diet; Diet, Reducing; Energy Intake; Energy Metabolism; Enzyme Inhibitors; Female; Insulin; Kinetics; Mice; Mice, Inbred C57BL; Obesity; Piperazines; Sulfonamides; Thiazoles; Weight Gain | 2006 |
A model for antipsychotic-induced obesity in the male rat.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Body Composition; Body Weight; Circadian Rhythm; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Haloperidol; Male; Obesity; Olanzapine; Piperazines; Rats; Rats, Sprague-Dawley; Thiazoles; Time Factors; Weight Gain | 2006 |
Alterations of lipid metabolism and gene expression in rat adipocytes during chronic olanzapine treatment.
Topics: Adipocytes; Animals; Antipsychotic Agents; Benzodiazepines; Cell Size; Drug Administration Schedule; Fatty Acid Synthases; Gene Expression Regulation; Glucose Transport Proteins, Facilitative; Haloperidol; Lipid Metabolism; Male; Obesity; Olanzapine; Piperazines; Rats; Rats, Sprague-Dawley; RNA; Statistics, Nonparametric; Sterol Esterase; Thiazoles; Weight Gain | 2007 |
Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance.
Topics: Animals; Blood Glucose; Body Weight; Dipeptidyl-Peptidase IV Inhibitors; Fatty Acids, Nonesterified; Glucose; Glucose Intolerance; Incretins; Insulin; Insulin Secretion; Islets of Langerhans; Isoleucine; Male; Models, Animal; Obesity; Rats; Rats, Zucker; Thiazoles; Time Factors; Tissue Culture Techniques; Triglycerides | 2008 |
A new potentiator of insulin action. Post-receptor activation in vitro.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Blood Glucose; Body Weight; Deoxyglucose; Diabetes Mellitus, Experimental; Drug Synergism; Glucose; Glycolysis; Insulin; Kinetics; Obesity; Rats; Rats, Inbred Strains; Receptor, Insulin; Thiazoles; Thiazolidinediones | 1983 |
Reduction of insulin resistance in obese and/or diabetic animals by 5-[4-(1-methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione (ADD-3878, U-63,287, ciglitazone), a new antidiabetic agent.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Obese; Obesity; Phospholipids; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidinediones; Triglycerides | 1983 |
Prevention of diabetes does not completely prevent insulin secretory defects in the ZDF rat.
Topics: Acarbose; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fasting; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Obesity; Pioglitazone; Pulsatile Flow; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Trisaccharides; Weaning | 1995 |
Insulin resistance and the prevention of diabetes mellitus.
Topics: Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 1994 |
Lipid abnormalities in tissues of the KKAy mouse: effects of pioglitazone on malonyl-CoA and diacylglycerol.
Topics: Animals; Blood; Diglycerides; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Liver; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscles; Obesity; Pioglitazone; Thiazoles; Thiazolidinediones | 1994 |
Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Gene Expression; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Muscles; Obesity; Pioglitazone; Receptors, Tumor Necrosis Factor; RNA, Messenger; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha | 1994 |
Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Eating; Fasting; Feeding Behavior; Female; Glucose Tolerance Test; Heart Rate; Hypoglycemic Agents; Insulin; Insulin Resistance; Macaca mulatta; Male; Obesity; Pioglitazone; Thiazoles; Thiazolidinediones; Tolbutamide; Triglycerides | 1994 |
Antihypertensive effects of CS-045 treatment in obese Zucker rats.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Chromans; Diuresis; Female; Hypoglycemic Agents; Insulin Resistance; Lipids; Male; Obesity; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Troglitazone | 1993 |
Effects of ciglitazone on blood pressure and intracellular calcium metabolism.
Topics: Animals; Blood Pressure; Calcium; Female; Insulin; Intracellular Membranes; Obesity; Platelet-Derived Growth Factor; Rats; Rats, Zucker; Signal Transduction; Thiazoles; Thiazolidinediones; Tumor Cells, Cultured | 1993 |
Studies on antidiabetic agents. XII. Synthesis and activity of the metabolites of (+/-)-5(-)[p(-)[2-(5-ethyl-2-pyridyl)ethoxy]benzyl]-2,4- thiazolidinedione (pioglitazone).
Topics: Animals; Biotransformation; Blood Glucose; Hydroxylation; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Obesity; Pioglitazone; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazoles; Thiazolidinediones | 1995 |
Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice.
Topics: Adipose Tissue; Amino Acid Sequence; Animals; Base Sequence; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; DNA Primers; DNA Probes; DNA, Complementary; Gene Expression Regulation; Glucose; Homeostasis; Hypoglycemic Agents; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Molecular Sequence Data; Obesity; Polymerase Chain Reaction; Protein Biosynthesis; Proteins; Rats; Rats, Zucker; Reference Values; RNA, Messenger; Thiazoles; Thiazolidinediones; Triglycerides | 1996 |
VLDL triglyceride kinetics in Wistar fatty rats, an animal model of NIDDM: effects of dietary fructose alone or in combination with pioglitazone.
Topics: Animals; Body Weight; Cholesterol; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Disease Models, Animal; Energy Intake; Fatty Acids, Nonesterified; Fructose; Hypoglycemic Agents; Lipase; Lipoprotein Lipase; Lipoproteins, VLDL; Liver; Obesity; Pioglitazone; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones; Thinness; Triglycerides | 1996 |
Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Base Sequence; Gene Expression Regulation; Hypoglycemic Agents; Leptin; Mice; Molecular Sequence Data; Obesity; Oligodeoxyribonucleotides; Protein Binding; Proteins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 1996 |
Effect of the thiazolidinedione BRL49653 and genetic obesity on hepatic gene expression in the Zucker rat.
Topics: Animals; Cell Line; Gene Expression; Hypoglycemic Agents; Liver; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Zucker; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones | 1995 |
Pioglitazone improves insulin signaling defects in skeletal muscle from Wistar fatty (fa/fa) rats.
Topics: Animals; Blood Glucose; Body Weight; Gene Expression; Hindlimb; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Male; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Pioglitazone; Rats; Rats, Mutant Strains; Rats, Wistar; Receptor, Insulin; Reference Values; Signal Transduction; Thiazoles; Thiazolidinediones; Triglycerides | 1996 |
Effect of troglitazone on leptin production. Studies in vitro and in human subjects.
Topics: Adipocytes; Adult; Animals; Blood Glucose; Cells, Cultured; Chromans; Fasting; Female; Glucose; Humans; Hyperinsulinism; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Leptin; Male; Middle Aged; Obesity; Protein Biosynthesis; Proteins; Thiazoles; Thiazolidinediones; Troglitazone | 1996 |
Euglycaemic and biological activities of novel thiazolidine-2,4-dione derivatives.
Topics: Animals; Blood Glucose; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Rats, Zucker; Thiazoles | 1995 |
Role of plasma insulin concentration in regulating glucose and lipid metabolism in lean and obese Zucker rats.
Topics: Administration, Oral; Animals; Blood Glucose; Cholesterol; Cholesterol, HDL; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Lipid Metabolism; Lipids; Male; Mice; Mice, Inbred Strains; Obesity; Rats; Rats, Zucker; Thiazoles; Thiazolidines; Time Factors; Triglycerides | 1997 |
Glitazones and NIDDM.
Topics: Animals; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 1997 |
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists.
Topics: Animals; Bexarotene; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Resistance; Ligands; Mice; Mice, Inbred C57BL; Mice, Obese; Nicotinic Acids; Obesity; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection | 1997 |
Troglitazone for non-insulin-dependent diabetes mellitus.
Topics: Administration, Oral; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hypercholesterolemia; Hypoglycemic Agents; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 1997 |
Antihypertensive and vasculo- and renoprotective effects of pioglitazone in genetically obese diabetic rats.
Topics: Animals; Aorta; Arteriosclerosis; Blood Glucose; Blood Pressure; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Epinephrine; Hypertension; Hypoglycemic Agents; Kidney Cortex; Kidney Glomerulus; Male; Norepinephrine; Obesity; Pioglitazone; Proteinuria; Rats; Rats, Inbred WF; Rats, Mutant Strains; Rats, Wistar; Sodium; Thiazoles; Thiazolidinediones; Triglycerides; Tunica Media | 1997 |
Is troglitazone a real indication for obese subjects with impaired glucose tolerance?
Topics: Chromans; Diabetes Mellitus, Type 2; Glucose Intolerance; Humans; Hypoglycemic Agents; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 1997 |
Induction of uncoupling protein-2 mRNA by troglitazone in the pancreatic islets of Zucker diabetic fatty rats.
Topics: Animals; Chromans; Hypoglycemic Agents; In Vitro Techniques; Ion Channels; Islets of Langerhans; Male; Membrane Transport Proteins; Mitochondrial Proteins; Obesity; Proteins; Rats; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Uncoupling Protein 2; Up-Regulation | 1997 |
Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat.
Topics: Adipocytes; Animals; Body Weight; Cell Differentiation; Fatty Acid Synthases; Female; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glucose; Glucose Transporter Type 4; Insulin Resistance; Leptin; Lipid Metabolism; Lipid Mobilization; Monosaccharide Transport Proteins; Muscle Proteins; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Pioglitazone; Proteins; Rats; Rats, Mutant Strains; Thiazoles; Thiazolidinediones | 1997 |
Leptin- or troglitazone-induced lipopenia protects islets from interleukin 1beta cytotoxicity.
Topics: Animals; Cell Survival; Cells, Cultured; Chromans; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Gene Transfer Techniques; Interleukin-1; Islets of Langerhans; Leptin; Lipids; Nitric Oxide; Obesity; Proteins; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 1997 |
Novel benzoxazole 2,4-thiazolidinediones as potent hypoglycemic agents. Synthesis and structure-activity relationships.
Topics: Animals; Benzopyrans; Benzoxazoles; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Male; Mice; Obesity; Pioglitazone; Rosiglitazone; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Troglitazone | 1997 |
Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes.
Topics: Animals; Apoptosis; Cells, Cultured; Ceramides; Chromans; Coenzyme A Ligases; Diabetes Mellitus; Diabetes Mellitus, Type 2; DNA Fragmentation; Enzyme Induction; Enzyme Inhibitors; Fatty Acids, Nonesterified; Guanidines; Homozygote; Humans; Hypoglycemic Agents; Islets of Langerhans; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Obesity; Palmitic Acid; Prediabetic State; Rats; Rats, Zucker; Repressor Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidinediones; Transcription, Genetic; Triazenes; Troglitazone | 1998 |
Pioglitazone time-dependently reduces tumour necrosis factor-alpha level in muscle and improves metabolic abnormalities in Wistar fatty rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Immunoenzyme Techniques; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Pioglitazone; Rats; Rats, Mutant Strains; Rats, Wistar; Sphingomyelin Phosphodiesterase; Thiazoles; Thiazolidinediones; Time Factors; Triglycerides; Tumor Necrosis Factor-alpha | 1998 |
Troglitazone regulation of glucose metabolism in human skeletal muscle cultures from obese type II diabetic subjects.
Topics: Adult; Cells, Cultured; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Glucose Transporter Type 1; Glycogen Synthase; Humans; Hypoglycemic Agents; Insulin; Middle Aged; Monosaccharide Transport Proteins; Muscle, Skeletal; Obesity; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone | 1998 |
Improved glucose tolerance in Zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide.
Topics: Administration, Oral; Animals; Blood Glucose; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Female; Glucose; Glucose Intolerance; Insulin; Isoleucine; Male; Obesity; Rats; Rats, Zucker; Reference Values; Thiazoles | 1998 |
Peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats.
Topics: Acetylglucosaminidase; Albuminuria; Animals; Blood Pressure; Body Weight; Histocytochemistry; Hypoglycemic Agents; Immunohistochemistry; Islets of Langerhans; Kidney; Kidney Diseases; Male; Obesity; Pancreas; Pancreatic Diseases; Proteinuria; Rats; Rats, Zucker; Rosiglitazone; Systole; Thiazoles; Thiazolidinediones | 1998 |
Pioglitazone-induced increase of insulin sensitivity in the muscles of the obese Zucker fa/fa rat cannot be explained by local adipocyte differentiation.
Topics: Adipocytes; Animals; Cell Differentiation; fas Receptor; Female; Gene Expression; Glucose; Glucose Clamp Technique; Hypoglycemic Agents; Insulin; Muscle, Skeletal; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Pioglitazone; Rats; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones | 1998 |
Targeted glycemic control in type 2 diabetes.
Topics: Aged; Algorithms; Anti-Obesity Agents; Biguanides; Blood Glucose; Blood Glucose Self-Monitoring; Chromans; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 1998 |
The new antidiabetic drug MCC-555 acutely sensitizes insulin signaling in isolated cardiomyocytes.
Topics: Animals; Blotting, Western; Glucose; Heart; Hypoglycemic Agents; Insulin; Male; Myocardium; Obesity; Phosphatidylinositol 3-Kinases; Precipitin Tests; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Rats, Zucker; Signal Transduction; Thiazoles; Thiazolidinediones | 1998 |
Role of skeletal muscle in thiazolidinedione insulin sensitizer (PPARgamma agonist) action.
Topics: Animals; Deoxyglucose; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Resistance; Male; Mice; Muscle, Skeletal; Myocardium; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 1998 |
A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.
Topics: Acyl-CoA Oxidase; Adipose Tissue; Animals; Blood Glucose; Body Weight; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Gene Expression; Hypoglycemic Agents; Insulin; Ligands; Lipid Metabolism; Liver; Male; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Obesity; Organ Size; Oxidoreductases; Radioligand Assay; Rats; Rats, Wistar; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Transcriptional Activation; Triglycerides | 1998 |
Improved metabolic status and insulin sensitivity in obese fatty (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats treated with the thiazolidinedione, MCC-555.
Topics: Animals; Basal Metabolism; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Fatty Acids; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver Glycogen; Male; Obesity; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Treatment Outcome; Triglycerides | 1998 |
Troglitazone ameliorates insulin resistance in a diabetic patient with Prader-Willi syndrome.
Topics: Adolescent; Blood Glucose; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Obesity; Prader-Willi Syndrome; Thiazoles; Thiazolidinediones; Troglitazone | 1998 |
Expression of leptin receptor in lung: leptin as a growth factor.
Topics: Animals; Bromodeoxyuridine; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Division; Cells, Cultured; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Leptin; Mice; Obesity; Proteins; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
The distribution of body mass index among individuals with and without schizophrenia.
Topics: Antipsychotic Agents; Body Mass Index; Clinical Trials as Topic; Comorbidity; Female; Health Surveys; Humans; Male; Obesity; Piperazines; Schizophrenia; Sex Factors; Thiazoles; United States; Weight Gain | 1999 |
Pregnancy after treatment with the insulin-sensitizing agent troglitazone in an obese woman with the hyperandrogenic, insulin-resistant acanthosis nigricans syndrome.
Topics: Acanthosis Nigricans; Adult; Blood Glucose; Chromans; Female; Gonadal Steroid Hormones; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Obesity; Pregnancy; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
15-Deoxy-delta(12,14) prostaglandin J2: a putative endogenous promoter of adipogenesis suppresses the ob gene.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Chromans; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Indomethacin; Leptin; Monosaccharide Transport Proteins; Muscle Proteins; Nuclear Proteins; Obesity; Prostaglandin D2; Proteins; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 1999 |
A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
Topics: Animals; Benzophenones; Chromans; Clone Cells; Diabetes Mellitus, Experimental; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Immunohistochemistry; Logistic Models; Obesity; Phenotype; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tyrosine | 1999 |
The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats.
Topics: Acetylcholine; Animals; Blood Pressure; Endothelium, Vascular; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Vascular Resistance; Vasodilator Agents | 1999 |
Rosiglitazone (BRL49653), a PPARgamma-selective agonist, causes peroxisome proliferator-like liver effects in obese mice.
Topics: Animals; Electrophoresis, Gel, Two-Dimensional; Hypoglycemic Agents; Liver; Male; Mice; Mice, Obese; Obesity; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 1999 |
Improvement in insulin resistance and the restoration of reduced phosphodiesterase 3B gene expression by pioglitazone in adipose tissue of obese diabetic KKAy mice.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Blood Glucose; Cyclic Nucleotide Phosphodiesterases, Type 3; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Pioglitazone; Thiazoles; Thiazolidinediones; Triglycerides | 1999 |
Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Chromans; Diabetes Mellitus; Eating; Hypoglycemic Agents; Islets of Langerhans; Lipids; Mitochondria; Obesity; Rats; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 1999 |
Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes.
Topics: Adipocytes; Adipose Tissue; Adult; Aged; DNA-Binding Proteins; Female; Gene Expression Regulation; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Ion Channels; Leptin; Male; Membrane Transport Proteins; Middle Aged; Mitochondrial Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Obesity; Phosphatidylinositol 3-Kinases; Proteins; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness; Transcription Factors; Transcription, Genetic; Uncoupling Protein 2 | 1999 |
Chronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat skeletal muscle glucose metabolism.
Topics: Animals; Biological Transport; Body Weight; Cell Line; Deoxyglucose; Glucose; In Vitro Techniques; Insulin; Ligands; Male; Muscle, Skeletal; Obesity; Oxazoles; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Thiazoles; Thiazolidinediones; Transcription Factors; Weight Gain | 1999 |
Amelioration by KRP-297, a new thiazolidinedione, of impaired glucose uptake in skeletal muscle from obese insulin-resistant animals.
Topics: Animals; Blood Glucose; Glucose; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Thiazoles; Thiazolidines | 1999 |
Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution.
Topics: Animals; Body Weight; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Hemodilution; Hemodynamics; Hypoglycemic Agents; Insulin; Leptin; Male; Obesity; Rats; Rats, Wistar; Rosiglitazone; Thiazoles; Thiazolidinediones | 1999 |
Assessment of human muscle glycogen synthesis and total glucose content by in vivo 13C MRS.
Topics: Adult; Carbon Isotopes; Chromans; Glucose; Glucose Clamp Technique; Glycogen; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Magnetic Resonance Spectroscopy; Male; Middle Aged; Muscle, Skeletal; Obesity; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Troglitazone improves insulin-stimulated glucose utilization associated with an increased muscle glycogen content in obese Zucker rats.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Blood Glucose; Body Weight; Chromans; Eating; Glucose Clamp Technique; Glucose Transporter Type 4; Glycogen; Hypoglycemic Agents; Insulin; Male; Metabolic Clearance Rate; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Pyruvate Dehydrogenase Complex; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Lipotoxic heart disease in obese rats: implications for human obesity.
Topics: Age Factors; Animals; Apoptosis; Blood Glucose; Body Weight; Chromans; DNA Fragmentation; Echocardiography; Heart Diseases; Humans; Insulin; Lipid Metabolism; Male; Microscopy, Electron; Myocardium; Obesity; Organ Size; Rats; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
["Insulin sensitizers" (glitazones), obesity, insulin resistance--is there a connection?].
Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Peroxisome Proliferators; Thiazoles | 2000 |
Troglitazone reduces plasminogen activator inhibitor-1 expression and secretion in cultured human adipocytes.
Topics: Adipocytes; Adult; Cell Differentiation; Cells, Cultured; Chromans; Culture Media; Female; Humans; Middle Aged; Obesity; Omentum; Osmolar Concentration; Plasminogen Activator Inhibitor 1; Reference Values; RNA, Messenger; Skin; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Tissue-specific actions of antidiabetic thiazolidinediones on the reduced fatty acid oxidation in skeletal muscle and liver of Zucker diabetic fatty rats.
Topics: Administration, Oral; Animals; Chromans; Diabetes Mellitus; Fatty Acids; Hypoglycemic Agents; Liver; Male; Muscle, Skeletal; Obesity; Oxidation-Reduction; Palmitic Acid; Rats; Rats, Zucker; Reference Values; Substrate Specificity; Thiazoles; Thiazolidinediones; Thiazolidines; Triglycerides; Troglitazone | 2000 |
Thiazolidinediones exert different effects on insulin resistance between dexamethasone-treated rats and wistar fatty rats.
Topics: Animals; Chromans; Dexamethasone; Drug Combinations; Glucocorticoids; Glucose; Glucose Clamp Technique; Homeostasis; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Obesity; Pioglitazone; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and zucker diabetic fatty rats and effects of rosiglitazone.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hyperglycemia; Hypoglycemic Agents; Hypothalamus; Insulin; Intracellular Signaling Peptides and Proteins; Leptin; Neuropeptides; Obesity; Orexins; Protein Precursors; Rats; Rats, Zucker; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness; Transcription, Genetic | 2000 |
Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonist, JTT-501, on diabetic complications in Zucker diabetic fatty rats.
Topics: Absorptiometry, Photon; Animals; Body Weight; Bone Density; Bone Diseases, Metabolic; Cataract; Chromans; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Eating; Hypoglycemic Agents; Isoxazoles; Male; Neural Conduction; Obesity; Pancreas; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone | 2000 |
v- and t-SNARE protein expression in models of insulin resistance: normalization of glycemia by rosiglitazone treatment corrects overexpression of cellubrevin, vesicle-associated membrane protein-2, and syntaxin 4 in skeletal muscle of Zucker diabetic fat
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression; Glucose Transporter Type 4; Hypoglycemic Agents; Immunoblotting; Insulin Resistance; Male; Membrane Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Qa-SNARE Proteins; R-SNARE Proteins; Rats; Rats, Sprague-Dawley; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Vesicle-Associated Membrane Protein 3 | 2000 |
Effects of troglitazone on blood concentrations of plasminogen activator inhibitor 1 in patients with type 2 diabetes and in lean and obese normal subjects.
Topics: Adult; Arteriosclerosis; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Female; Fibrinolysis; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Plasminogen Activator Inhibitor 1; Thiazoles; Thiazolidinediones; Tissue Plasminogen Activator; Troglitazone | 2000 |
Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets.
Topics: Adenoviridae; Animals; CCAAT-Enhancer-Binding Proteins; Chromans; DNA-Binding Proteins; Genetic Vectors; Hyperinsulinism; Hypolipidemic Agents; Islets of Langerhans; Leptin; Liver; Male; Nuclear Proteins; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation | 2000 |
A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice.
Topics: Adipose Tissue; Animals; Body Weight; Carrier Proteins; Diabetes Mellitus; Hypoglycemic Agents; Ion Channels; Male; Membrane Proteins; Mice; Mice, Mutant Strains; Mitochondrial Proteins; Obesity; Organ Size; Quinolines; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transcription Factors; Uncoupling Protein 1 | 2000 |
Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Eating; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Nicotinic Acids; Obesity; Rats; Rats, Zucker; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors | 2000 |
[Are PPAR-gamma-agonists a secure choice in treatment of overweight diabetic patients?].
Topics: Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Obesity; Thiazoles; Weight Gain | 2000 |
Troglitazone prevents and reverses dyslipidemia, insulin secretory defects, and histologic abnormalities in a rat model of naturally occurring obese diabetes.
Topics: Adipose Tissue; Aging; Animals; Blood Glucose; Body Weight; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Eating; Fasting; Fatty Acids, Nonesterified; Glucose Tolerance Test; Hyperlipidemias; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Obesity; Organ Size; Pancreas; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 2000 |
Effects of a low-energy diet and an insulin-sensitizing agent on ambulatory blood pressure in overweight hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Chromans; Diet, Reducing; Female; Humans; Hypertension; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Obesity; Thiazoles; Thiazolidinediones; Troglitazone; Weight Loss | 2000 |
Troglitazone inhibits the expression of inducible nitric oxide synthase in adipocytes in vitro and in vivo study in 3T3-L1 cells and Otsuka Long-Evans Tokushima Fatty rats.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Chromans; Escherichia coli; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Interferon-gamma; Lipopolysaccharides; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Obesity; Rats; Rats, Long-Evans; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha | 2000 |
Effects of pioglitazone on promoting energy storage, not expenditure, in brown adipose tissue of obese fa/fa Zucker rats: comparison to CL 316,243.
Topics: Adipose Tissue, Brown; Animals; Carrier Proteins; Dioxoles; DNA; Energy Metabolism; Female; Hypoglycemic Agents; Ion Channels; Membrane Proteins; Mitochondrial Proteins; Obesity; Pioglitazone; Proteins; Rats; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones; Uncoupling Protein 1 | 2000 |
Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the li
Topics: Adipose Tissue; Animals; Blotting, Northern; Chromans; Diabetes Mellitus; Gene Expression Regulation; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2000 |
Mechanisms of dysregulation of 11 beta-hydroxysteroid dehydrogenase type 1 in obese Zucker rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adipose Tissue; Adrenal Glands; Adrenalectomy; Analysis of Variance; Animals; Blood Glucose; Corticosterone; Eating; Hydroxysteroid Dehydrogenases; Hypertrophy; Hypoglycemic Agents; Insulin; Liver; Male; Metformin; Obesity; Omentum; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain | 2000 |
Exercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat.
Topics: Animals; Chromans; Female; Glucose Clamp Technique; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Monosaccharide Transport Proteins; Motor Activity; Muscle Proteins; Obesity; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Zucker; Reference Values; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Dietary fat-induced increase in blood pressure and insulin resistance in rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Blood Pressure; Body Weight; Chromans; Dietary Carbohydrates; Dietary Fats; Dietary Fats, Unsaturated; Fatty Acids, Nonesterified; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Obesity; Rats; Rats, Wistar; Sucrose; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 2000 |
The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat.
Topics: Adipose Tissue, Brown; Animals; Body Weight; Carrier Proteins; Eating; Ion Channels; Membrane Proteins; Membrane Transport Proteins; Mitochondrial Proteins; Nicotinic Acids; Obesity; Proteins; Rats; Rats, Zucker; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Uncoupling Protein 1; Uncoupling Protein 2; Uncoupling Protein 3; Weight Gain | 2000 |
A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 antagonist, J-115814.
Topics: Animals; Appetite Depressants; CHO Cells; Cricetinae; Feeding Behavior; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Obesity; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Thiazoles | 2001 |
American Diabetes Association 60th Scientific Sessions, 2000: thiazolidinediones, obesity, and related topics.
Topics: Animals; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Leptin; Lipids; Obesity; Societies, Medical; Thiazoles | 2001 |
The hormone resistin links obesity to diabetes.
Topics: 3T3 Cells; Adipocytes; Amino Acid Sequence; Animals; Base Sequence; Chromosomes, Human, Pair 19; Cloning, Molecular; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet; DNA; Female; Gene Expression Regulation; Glucose Intolerance; Hormones; Hormones, Ectopic; Humans; Hypoglycemic Agents; Insulin Antagonists; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nerve Growth Factor; Neutralization Tests; Obesity; Proteins; Resistin; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones | 2001 |
Lipid lowering explains the insulin sensitivity enhancing effects of a thiazolidinedione, 5-(4-(2-(2-phenyl-4-oxazolyl)ethoxy)benzyl)-2,4 thiazolidinedione.
Topics: Animals; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Liver; Obesity; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Triglycerides | 2000 |
Troglitazone reduces plasma levels of tumour necrosis factor-alpha in obese patients with type 2 diabetes.
Topics: Blood Glucose; C-Peptide; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Obesity; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha | 2000 |
A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis.
Topics: Adult; Alanine Transaminase; Chromans; Fatty Liver; Female; Humans; Hypoglycemic Agents; Obesity; Pilot Projects; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
Suppression of nuclear factor-kappaB and stimulation of inhibitor kappaB by troglitazone: evidence for an anti-inflammatory effect and a potential antiatherosclerotic effect in the obese.
Topics: Adult; Anti-Inflammatory Agents; Arteriosclerosis; Blood Glucose; C-Reactive Protein; Cell Nucleus; Chemokine CCL2; Chromans; Female; Humans; I-kappa B Proteins; Insulin; Intercellular Adhesion Molecule-1; Interleukin-10; Leukocytes, Mononuclear; Male; Middle Aged; NADPH Oxidases; NF-kappa B; Obesity; Phosphoproteins; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha | 2001 |
The role of PPARgamma as a thrifty gene both in mice and humans.
Topics: Adipose Tissue; Animals; Case-Control Studies; Diabetes Mellitus, Type 2; Dietary Fats; Humans; Hypertrophy; Insulin Resistance; Leptin; Mice; Mice, Knockout; Models, Biological; Obesity; Polymorphism, Genetic; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2000 |
Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.
Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression; Glucose Tolerance Test; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Liver; Male; Muscle, Skeletal; Nicotinic Acids; Obesity; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors | 2001 |
Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover.
Topics: Animals; Apoptosis; Chromans; Diabetes Mellitus, Type 2; Fatty Acids; Hypoglycemic Agents; Islets of Langerhans; Lipid Metabolism; Obesity; Oxidation-Reduction; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
2,4-Thiazolidinediones as potent and selective human beta3 agonists.
Topics: Adrenergic beta-3 Receptor Agonists; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Mice; Mice, Knockout; Mice, Transgenic; Obesity; Structure-Activity Relationship; Thiazoles; Thiazolidinediones | 2001 |
Troglitazone corrects metabolic changes but not vascular dysfunction in dietary-obese rats.
Topics: Acetylcholine; Animals; Blood Glucose; Body Weight; Chromans; Diet; Dose-Response Relationship, Drug; Endothelium, Vascular; Energy Metabolism; Fatty Acids, Nonesterified; Female; Hypoglycemic Agents; In Vitro Techniques; Insulin; Leptin; Mesenteric Arteries; Nitroprusside; Norepinephrine; Obesity; Potassium Chloride; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport.
Topics: Animals; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Blood Glucose; Cell Line; Cholesterol; Cholesterol, HDL; Drug Design; Fasting; Fibroblasts; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Intestinal Mucosa; Intestines; Macaca mulatta; Macrophages; Male; Metabolic Diseases; Obesity; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Substrate Specificity; Thiazoles; Transcription Factors; Triglycerides | 2001 |
Effect of obesity and troglitazone on expression of two glutathione peroxidases: cellular and extracellular types in serum, kidney and adipose tissue.
Topics: Adipose Tissue; Animals; Blood Glucose; Blotting, Western; Body Weight; Chromans; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Kidney; Male; Obesity; Organ Size; Rats; Rats, Inbred OLETF; Rats, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha | 2001 |
Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death.
Topics: Aging; Animals; Blood Glucose; Body Weight; Cell Death; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Obesity; Organ Size; Pancreas; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones | 2001 |
Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypertriglyceridemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Kinetics; Lipid Mobilization; Lipoproteins, VLDL; Liver; Male; Metabolic Clearance Rate; Muscle, Skeletal; Obesity; Oxidation-Reduction; Polyethylene Glycols; Postprandial Period; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Triglycerides | 2001 |
Antidiabetic treatment for NASH?
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Chromans; Diabetes Mellitus; DNA-Binding Proteins; Fatty Liver; Hepatitis; Hypoglycemic Agents; Islets of Langerhans; Leptin; Liver; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists.
Topics: Adipocytes; Animals; Benzophenones; Down-Regulation; Hormones, Ectopic; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2001 |
Insulin-sensitizing action of rosiglitazone is enhanced by preventing hyperphagia.
Topics: Animals; Body Weight; Carrier Proteins; Eating; Food Deprivation; Hyperphagia; Hypoglycemic Agents; Hypothalamus; Insulin Resistance; Ion Channels; Leptin; Male; Mitochondrial Proteins; Neuropeptide Y; Obesity; Rats; Rats, Wistar; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Uncoupling Protein 3 | 2001 |
Troglitazone reduces the expression of PPARgamma while stimulating that of PPARalpha in mononuclear cells in obese subjects.
Topics: Adult; Antioxidants; Blood Glucose; Blotting, Western; Chromans; Female; Humans; Insulin; Leukocytes, Mononuclear; Linoleic Acids; Linoleic Acids, Conjugated; Lipids; Male; Middle Aged; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
A thiazolidinedione improves in vivo insulin action on skeletal muscle glycogen synthase in insulin-resistant monkeys.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Glucose Clamp Technique; Glucose-6-Phosphate; Glycogen Synthase; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Resistance; Macaca mulatta; Male; Muscle, Skeletal; Obesity; Thiazoles | 2000 |
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance.
Topics: Adipocytes; Adipose Tissue; Analysis of Variance; Animals; Blood Glucose; Cell Division; Cell Size; DNA; Fatty Acids, Nonesterified; Feeding Behavior; Female; Hyperlipidemias; Hypoglycemic Agents; Insulin; Insulin Resistance; Magnetic Resonance Imaging; Obesity; Pioglitazone; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Thinness; Triglycerides; Weight Gain | 2001 |
Diabetic KKAy mice exhibit increased hepatic PPARgamma1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones.
Topics: Animals; Chromans; Diabetes Mellitus; Fatty Liver; Gene Expression; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Obesity; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation | 2001 |
The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance.
Topics: Adipocytes; Animals; Heterozygote; Insulin; Insulin Resistance; Liver; Mice; Muscles; Obesity; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Transcription Factors; Triglycerides; Up-Regulation | 2001 |
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
Topics: 3T3 Cells; Adipose Tissue; Animals; Benzhydryl Compounds; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Epoxy Compounds; Fatty Acids; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Leptin; Mice; Mice, Knockout; Nicotinic Acids; Obesity; Receptors, Adrenergic, beta-3; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors | 2001 |
Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Administration, Oral; Animals; Blood Glucose; Body Weight; Glucose; Glucose Clamp Technique; Glucose Transporter Type 1; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness | 2001 |
Increased lymphatic lipid transport in genetically diabetic obese rats.
Topics: Animals; Bile Acids and Salts; Body Weight; Carrier Proteins; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Energy Intake; Fistula; Hypoglycemic Agents; Lymphatic System; Male; Obesity; Phosphatidylcholines; Physical Conditioning, Animal; Rats; Rats, Inbred OLETF; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 2002 |
Thiazolidinediones influence plasma steroids of male obese Zucker rats.
Topics: Animals; Blood Glucose; Body Weight; Chromans; Glucose; Hormones; Insulin; Male; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Troglitazone improves endothelial function and augments renal klotho mRNA expression in Otsuka Long-Evans Tokushima Fatty (OLETF) rats with multiple atherogenic risk factors.
Topics: Animals; Arteriosclerosis; Chromans; Endothelium, Vascular; Glucuronidase; Hypertension; Kidney; Klotho Proteins; Male; Membrane Proteins; Metabolic Diseases; Obesity; Rats; Rats, Inbred OLETF; Risk Factors; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilator Agents | 2001 |
A treatment for Mr WP: thiazolidinediones after troglitazone.
Topics: Aged; Animals; Body Mass Index; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Knockout; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
Psychotropic drugs and adverse events in the treatment of bipolar disorders revisited.
Topics: Anticonvulsants; Benzodiazepines; Bipolar Disorder; Dibenzothiazepines; Female; Fructose; Humans; Lamotrigine; Male; Obesity; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Triazines | 2002 |
Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the zucker Fatty rat heart.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Heart; Heart Rate; Hypoglycemic Agents; Insulin Resistance; Myocardial Ischemia; Myocardial Reperfusion; Obesity; Organ Size; Perfusion; Rats; Rats, Zucker; Reference Values; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors | 2002 |
Troglitazone improves GLUT4 expression in adipose tissue in an animal model of obese type 2 diabetes mellitus.
Topics: Adipose Tissue; Animals; Blood Glucose; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acids, Nonesterified; Gene Expression Regulation; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Obesity; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Reference Values; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 2002 |
A peroxisome proliferator-activated receptor gamma agonist influenced daily profile of energy expenditure in genetically obese diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diet; Energy Metabolism; Hypoglycemic Agents; Leptin; Lipids; Obesity; Organ Size; Pancreas; Pioglitazone; Rats; Rats, Inbred OLETF; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha | 2002 |
Effects of combined pioglitazone and metformin on diabetes and obesity in Wistar fatty rats.
Topics: Adipose Tissue; Animals; Body Weight; Diabetes Mellitus; Drug Therapy, Combination; Eating; Glycogen; Hypoglycemic Agents; Ketone Bodies; Liver; Male; Metformin; Muscle, Skeletal; Obesity; Organ Size; Pioglitazone; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones | 2002 |
Blockade of body weight gain and plasma corticosterone levels in Zucker fatty rats using an orally active neuropeptide Y Y1 antagonist.
Topics: Adipose Tissue; Administration, Oral; Analysis of Variance; Animals; Appetite Depressants; Cell Size; Corticosterone; Eating; Male; Models, Animal; Morpholines; Obesity; Rats; Rats, Zucker; Receptors, Neuropeptide Y; Thiazoles; Weight Gain | 2002 |
The effect of troglitazone on plasma homocysteine, hepatic and red blood cell S-adenosyl methionine, and S-adenosyl homocysteine and enzymes in homocysteine metabolism in Zucker rats.
Topics: Animals; Chromans; Cystathionine beta-Synthase; Erythrocytes; Female; Homocysteine; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Obesity; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Thiazoles; Thiazolidinediones; Thinness; Troglitazone | 2002 |
Increased lipolysis and decreased leptin production by human omental as compared with subcutaneous preadipocytes.
Topics: Adipocytes; Adult; Aged; Body Mass Index; Cell Differentiation; Female; Glycerol; Humans; Hypoglycemic Agents; Leptin; Lipolysis; Male; Middle Aged; Norepinephrine; Obesity; Omentum; RNA, Messenger; Rosiglitazone; Skin; Thiazoles; Thiazolidinediones; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2002 |
Normalization of skeletal muscle glycogen synthesis and glycolysis in rosiglitazone-treated Zucker fatty rats: an in vivo nuclear magnetic resonance study.
Topics: Animals; Disease Models, Animal; Gluconeogenesis; Glycolysis; Kinetics; Magnetic Resonance Spectroscopy; Models, Biological; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Reference Values; Rosiglitazone; Thiazoles; Thiazolidinediones | 2002 |
Combination of insulin and thiazolidinedione therapy in massively obese patients with Type 2 diabetes.
Topics: Adult; Aged; Body Mass Index; Body Weight; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Edema; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones | 2002 |
Pioglitazone increases insulin sensitivity by activating insulin receptor kinase.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 2; Drug Hypersensitivity; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Obesity; Phosphorylation; Pioglitazone; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Thiazoles; Thiazolidinediones | 1992 |
Treatment of insulin-resistant mice with the oral antidiabetic agent pioglitazone: evaluation of liver GLUT2 and phosphoenolpyruvate carboxykinase expression.
Topics: Animals; Crosses, Genetic; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Insulin; Insulin Resistance; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Monosaccharide Transport Proteins; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Pioglitazone; RNA, Messenger; Thiazoles; Thiazolidinediones | 1992 |
The effect of CP 68,722, a thiozolidinedione derivative, on insulin sensitivity in lean and obese Zucker rats.
Topics: Animals; Benzopyrans; Glucose; Glucose Clamp Technique; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Obesity; Osmolar Concentration; Rats; Rats, Zucker; Reference Values; Thiazoles; Thiazolidinediones | 1991 |
Effects of pioglitazone on glucose and lipid metabolism in Wistar fatty rats.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Glucose Tolerance Test; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Muscles; Obesity; Pioglitazone; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidinediones | 1990 |
Insulin resistance is accompanied by impairment of amylase-gene expression in the exocrine pancreas of the obese Zucker rat.
Topics: Amylases; Animals; Female; Gene Expression Regulation; Glucose; Insulin Resistance; Obesity; Pancreas; Protein Biosynthesis; Rats; Rats, Mutant Strains; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones | 1986 |
The hypoglycemic effect of ciglitazone in obese, hyperglycemic animal models.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Disease Models, Animal; Glycolysis; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Obese; Mitochondria; Obesity; Oxygen Consumption; Receptor, Insulin; Thiazoles; Thiazolidinediones | 1988 |
A review of the effects of ciglitazone on the pancreatic islets of obese, hyperglycemic mice.
Topics: Animals; Hyperglycemia; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Mice; Mice, Obese; Obesity; Thiazoles; Thiazolidinediones | 1988 |
Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats.
Topics: Adipose Tissue; Animals; Benzopyrans; Blood Glucose; Chromans; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Ketone Bodies; Lactates; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Rats, Inbred Strains; Rats, Zucker; Receptor, Insulin; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 1988 |
Changes in individual rates of pancreatic enzyme and isoenzyme biosynthesis in the obese Zucker rat.
Topics: Amino Acids; Animals; Blood Glucose; Eating; Insulin; Isoelectric Focusing; Isoenzymes; Kinetics; Obesity; Pancreas; Proteins; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones | 1987 |