Page last updated: 2024-08-21

thiazoles and Neurodegenerative Diseases

thiazoles has been researched along with Neurodegenerative Diseases in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.45)18.2507
2000's23 (33.33)29.6817
2010's41 (59.42)24.3611
2020's4 (5.80)2.80

Authors

AuthorsStudies
Ciszkowicz, E; Creaven, B; Jenkins, H; Kamiński, D; Karcz, D; Lecka-Szlachta, K; Matwijczuk, A; Miłoś, A; Radomski, P; Ślusarczyk, L; Starzak, K1
Chaudhary, J; Chopra, B; Dhingra, A; Gupta, J; Jain, A; Kaushik, A; Sharma, V1
Kondapalli, VG; Mithula, S; Murugesan, S; Nandikolla, A1
Collins-Praino, LE; Corrigan, F; Guglietti, B; Mustafa, S; Sivasankar, S1
Graff-Radford, J; Jack, CR; Jones, DT; Knopman, DS; Lesnick, TG; Lowe, VJ; Machulda, MM; Mielke, MM; Murray, ME; Petersen, RC; Przybelski, SA; Roberts, RO; Vassilaki, M; Vemuri, P1
Ali, F; Josephs, KA1
Ali, F; Boeve, BF; Jack, CR; Josephs, KA; Knopman, DS; Lowe, VJ; Martin, PR; Petersen, RC; Senjem, ML; Whitwell, JL1
Dolgin, E1
Albertson, SM; Boeve, B; Dickson, DW; Jack, CR; Jones, DT; Kantarci, K; Knopman, D; Lowe, VJ; Lundt, ES; Murray, ME; Parisi, JE; Petersen, RC; Przybelski, SA; Senjem, ML1
Ami, D; Doglia, SM; Lotti, M; Natalello, A1
Cinar, Y; Dornieden, S; Funke, SA; Jiang, N; Korth, C; Müller-Schiffmann, A; Sticht, H; Willbold, D; Wördehoff, M1
Bao, L; Dong, H; Feng, X; Gao, Q; Gao, Y; Hao, J; Liang, N; Liu, H; Peng, L; Sun, J; Yu, X; Yue, Q; Zhang, J; Zhu, D1
Burrell, JR; Hodges, JR; Hornberger, M; Rowe, CC; Villemagne, VL1
Hamada, K; Ishii, K; Iwata, A; Mannen, T; Murayama, S; Saito, Y; Sakurai, Y; Sonoo, M; Sugimoto, I; Tsuji, S1
Gao, J; Gräff, J; Kahn, M; Ota, KT; Rei, D; Samiei, A; Tsai, LH1
Berry, DB; Bhardwaj, S; DeArmond, SJ; Geva, M; Giles, K; Lu, D; Oehler, A; Prusiner, SB; Renslo, AR; Watts, JC1
Klunk, WE; Perani, D1
Haase, CM; Jagust, WJ; Landau, SM; Madison, CM; Oh, H; Rabinovici, GD; Villeneuve, S; Wirth, M1
Jack, CR; Josephs, KA; Kantarci, K; Reid, RI; Schwarz, CG; Whitwell, JL1
Amani, S; Naeem, A2
Burrell, JR; Hodges, JR; Hornberger, M; Huang, N1
Ahn, JY; Cho, SW; Choi, J; Choi, SY; Han, AR; Kim, EA1
Crews, LA; Gonzales, T; Kouznetsova, VL; Masliah, E; Overk, CR; Patrick, C; Paulino, A; Price, D; Rockenstein, E; Stocking, E; Tsigelny, IF; Wrasidlo, W1
Gunter, JL; Jack, CR; Knopman, DS; Lowe, VJ; Mielke, MM; Pankratz, VS; Petersen, RC; Preboske, GM; Rocca, WA; Senjem, ML; Vemuri, P; Weigand, SD; Wiste, HJ1
Aizenstein, HJ; Becker, JT; Cohen, A; Coleman, RL; DeKosky, ST; Ikonomovic, M; Klunk, WE; Kuller, LH; Lopez, OL; Mathis, C; McDade, E; Price, J; Snitz, B; Weissfeld, L1
Boeve, BF; Gunter, JL; Jack, CR; Jones, DT; Kantarci, K; Knopman, DS; Lowe, VJ; Lundt, ES; Machulda, MM; Mielke, MM; Petersen, RC; Roberts, RO; Senjem, ML; Vemuri, P; Weigand, SD; Wiste, HJ1
Apostolova, LG; Drubach, DA; Duffy, JR; Gunter, JL; Jack, CR; Josephs, KA; Kantarci, K; Lowe, VJ; Machulda, MM; Madhavan, A; Petersen, RC; Przybelski, SA; Reid, RI; Schwarz, CG; Senjem, ML; Strand, EA; Whitwell, JL1
Brown, EE; Chow, TW; Felsky, D; Freedman, M; Graff-Guerrero, A; Houle, S; Ismail, Z; Mizrahi, R; Mulsant, BH; Pollock, BG; Tang-Wai, DF; Verhoeff, NP; Voineskos, AN; Wilson, AA1
Dickson, DW; Duffy, JR; Jack, CR; Josephs, KA; Lowe, V; Murray, ME; Senjem, ML; Tacik, P; Tosakulwong, N; Whitwell, JL1
Kaminsky, YG; Kosenko, EA1
Jeong, MS; Kang, JH1
Davey, GP; Kilbride, SM; Telford, JE1
Goto, Y; Hasegawa, K; Morinaga, A; Naiki, H; Nomura, R; Ookoshi, T; Ozawa, D; Yamada, M1
Boyd, A; Jones, G; Masters, CL; Pejoska, S; Pike, K; Power, M; Rowe, CC; Villemagne, VL1
Frisoni, GB; Giannakopoulos, P1
Cyr, DM; Summers, DW1
Chen, X; Fushimi, K; Jayaram, N; Li, L; Long, C; Wu, JY1
Noormägi, A; Palumaa, P; Primar, K; Tõugu, V1
Davies, HA; Madine, J; Middleton, DA1
Clark, T; Macauley, MS; Shan, X; Skorobogatko, Y; Vocadlo, DJ; Vosseller, K; Yuzwa, SA1
Byrnes, KR; Faden, AI; Loane, DJ; Stoica, BA; Zhang, J1
Duffy, JR; Jack, CR; Josephs, KA; Lowe, VJ; Machulda, MM; Master, AV; Senjem, ML; Strand, EA; Whitwell, JL1
Bannach, O; Birkmann, E; Funke, SA; Hübinger, S; Willbold, D1
David, P; Naidu, M; Phan, CW; Sabaratnam, V; Wong, WL1
Balducci, C; Biasini, E; Borsello, T; Colombo, L; Diomede, L; Fluharty, BR; Forloni, G; Gobbi, M; Harris, DA; La Vitola, P; Messa, M; Sclip, A; Stravalaci, M1
Chen, YR; Chiang, CH; Kuo, PH; Liang, JR; Shen, JC; Wang, S; Wang, YT; Yuan, HS1
Allen, B; Atzori, C; Craxton, M; Crowther, RA; Emson, PC; Ghetti, B; Goedert, M; Holzer, M; Ingram, E; Jakes, R; Migheli, A; Smith, MJ; Spillantini, MG; Takao, M; Virdee, K; Yoshida, H1
Drozak, J; Winiarska, K1
Chan, SL; Gilman, CP; Greig, N; Guo, Z; Mattson, MP; Zhu, X1
Bellmann, C; Giasson, BI; Horiguchi, T; Ischiropoulos, H; Lee, VM; LightFoot, R; Richter-Landsberg, C; Trojanowski, JQ; Uryu, K1
Edmonds, B; Glabe, CG; Hall, JE; Kayed, R; McIntire, TM; Milton, SC; Sokolov, Y1
Boshuizen, RS; Langedijk, JP; Langeveld, JP; Meloen, RH; Salmona, M; Williams, A1
Gudkov, AV; Komarova, EA1
Anderluh, G; Ceru, S; Gutierrez-Aguirre, I; Kopitar-Jerala, N; Macek, P; Rabzelj, S; Turk, V; Zerovnik, E1
Arendt, T; Brückner, MK; Gärtner, U; Gebhardt, R; Gruschka, H; Seeger, G; Ueberham, E; Ueberham, U1
Allsop, D; Cooper, LJ; El-Agnaf, OM; Fullwood, NJ; German, MJ; Hayashi, Y; Paleologou, KE; Tabner, BJ; Turnbull, S1
Caricasole, A; Gaviraghi, G; Terstappen, GC1
Arnold, SE; Chatterjee, A; Clark, CM; Coslett, HB; Farmer, J; Forman, MS; Grossman, M; Hurtig, HI; Johnson, JK; Karlawish, JH; Lee, VM; Miller, BL; Rosen, HJ; Trojanowski, JQ; Van Deerlin, V1
Beart, PM; Bernard, O; Cheung, NS; Halliwell, B; Jenner, AM; Koh, CH; Laughton, KM; Li, QX; Masters, CL; Wenk, M; Whiteman, M; Wong, BS1
Faden, AI; Lea, PM1
Glabe, CG; Kayed, R1
Kerk, S; Meng Lim, T; Zhou, Z1
Bianchi, E; Curran, MD; El-Agnaf, OM; Ingenito, R; Jakes, R; Middleton, D; Neill, D; Pessi, A; Wallace, A1
Chung, KC; Kim, J; Kim, YS; Lee, D; Lee, EK; Paik, SR; Sung, JY1
Colado, MI; Esteban, B; Green, AR; O'Shea, E1
Akagi, T; Hashikawa, T; Kikuchi, N; Matsuda, K; Murayama, M; Murayama, O; Nakao, S; Park, JM; Sato, S; Sun, X; Takashima, A; Tanemura, K; Yamaguchi, H; Yoshiike, Y1
Abramova, NA; Bennett, JP; Cassarino, DS; Khan, SM; Painter, TW1
Chen, D; Egan, JM; Greig, NH; Lahiri, DK; Perry, T; Shaw, KT; Zhou, J1

Reviews

6 review(s) available for thiazoles and Neurodegenerative Diseases

ArticleYear
1,3-thiazole Derivatives: A Scaffold with Considerable Potential in the Treatment of Neurodegenerative Diseases.
    Current topics in medicinal chemistry, 2023, Volume: 23, Issue:23

    Topics: Anti-Infective Agents; Antiviral Agents; Drug Design; Humans; Neurodegenerative Diseases; Thiazoles

2023
1,8-naphthyridine derivatives: an updated review on recent advancements of their myriad biological activities.
    Future medicinal chemistry, 2021, Volume: 13, Issue:18

    Topics: Animals; Anti-Infective Agents; Antidepressive Agents; Antineoplastic Agents; Antioxidants; Antiviral Agents; Drug Discovery; Enoxacin; Humans; Isomerism; Molecular Structure; Nalidixic Acid; Naphthyridines; Neurodegenerative Diseases; Structure-Activity Relationship; Thiazoles

2021
Fyn Kinase Activity and Its Role in Neurodegenerative Disease Pathology: a Potential Universal Target?
    Molecular neurobiology, 2021, Volume: 58, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzamides; Central Nervous System; Dasatinib; Humans; Molecular Targeted Therapy; Multiple Sclerosis; Myelin Sheath; Nerve Tissue Proteins; Neurodegenerative Diseases; Oligodendroglia; Parkinson Disease; Piperidines; Proto-Oncogene Proteins c-fyn; PrPC Proteins; Pyridines; Receptors, N-Methyl-D-Aspartate; T-Cell Antigen Receptor Specificity; T-Lymphocyte Subsets; tau Proteins; Thiazoles

2021
[Glutathione in therapy].
    Postepy higieny i medycyny doswiadczalnej, 2002, Volume: 56, Issue:4

    Topics: Animals; Cysteine; Diabetes Mellitus; Glutathione; Humans; Infections; Neurodegenerative Diseases; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

2002
Prospective therapeutic applications of p53 inhibitors.
    Biochemical and biophysical research communications, 2005, Jun-10, Volume: 331, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzothiazoles; Drug Synergism; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Radiation-Protective Agents; Thiazoles; Toluene; Tumor Suppressor Protein p53

2005
Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP.
    CNS drug reviews, 2006,Summer, Volume: 12, Issue:2

    Topics: Animals; Humans; Neurodegenerative Diseases; Pain; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Substance-Related Disorders; Thiazoles

2006

Trials

2 trial(s) available for thiazoles and Neurodegenerative Diseases

ArticleYear
A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, May-22, Volume: 33, Issue:21

    Topics: Analysis of Variance; Animals; Atrophy; Brain; Caloric Restriction; Case-Control Studies; Cognition Disorders; Cyclin-Dependent Kinase 5; Disease Models, Animal; Double-Blind Method; Excitatory Postsynaptic Potentials; Female; Green Fluorescent Proteins; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Male; Memory Disorders; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Neurodegenerative Diseases; Phosphopyruvate Hydratase; Phosphotransferases; Piperidines; Silver Staining; Sirtuin 1; Synapses; Thiazoles; Tumor Suppressor Protein p53; Vitamin E

2013
Amyloid, neurodegeneration, and small vessel disease as predictors of dementia in the oldest-old.
    Neurology, 2014, Nov-11, Volume: 83, Issue:20

    Topics: Aged, 80 and over; Amyloid; Aniline Compounds; Brain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Dementia; Disease Progression; Double-Blind Method; Female; Geriatric Assessment; Ginkgo biloba; Humans; Longitudinal Studies; Male; Neurodegenerative Diseases; Phytotherapy; Plant Extracts; Positron-Emission Tomography; Predictive Value of Tests; Thiazoles

2014

Other Studies

61 other study(ies) available for thiazoles and Neurodegenerative Diseases

ArticleYear
Novel Coumarin-Thiadiazole Hybrids and Their Cu(II) and Zn(II) Complexes as Potential Antimicrobial Agents and Acetylcholinesterase Inhibitors.
    International journal of molecular sciences, 2021, Sep-08, Volume: 22, Issue:18

    Topics: Acetylcholinesterase; Anti-Bacterial Agents; Anti-Infective Agents; Cholinesterase Inhibitors; Copper; Coumarins; Crystallography, X-Ray; Escherichia coli; Ligands; Magnetic Resonance Spectroscopy; Metals; Microbial Sensitivity Tests; Neurodegenerative Diseases; Pseudomonas aeruginosa; Schiff Bases; Spectrometry, Fluorescence; Spectrophotometry, Atomic; Staphylococcus aureus; Staphylococcus epidermidis; Thiadiazoles; Thiazoles; Zinc

2021
Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals.
    JAMA neurology, 2017, 06-01, Volume: 74, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Female; Humans; Magnetic Resonance Imaging; Male; Neurodegenerative Diseases; Positron-Emission Tomography; Protective Factors; Risk Factors; Thiazoles

2017
Corticobasal degeneration: key emerging issues.
    Journal of neurology, 2018, Volume: 265, Issue:2

    Topics: Aniline Compounds; Basal Ganglia; Carbolines; Cerebral Cortex; Dopamine Agents; History, 20th Century; Humans; Levodopa; Neurodegenerative Diseases; Positron-Emission Tomography; Supranuclear Palsy, Progressive; Thiazoles

2018
[
    Journal of neurology, 2018, Volume: 265, Issue:5

    Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Apraxias; Brain; Brain Mapping; Carbolines; Cohort Studies; Female; Humans; Linear Models; Male; Middle Aged; Neurodegenerative Diseases; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles

2018
The brain's traffic problems.
    Science (New York, N.Y.), 2019, Jan-18, Volume: 363, Issue:6424

    Topics: Acrylamides; Active Transport, Cell Nucleus; Amyotrophic Lateral Sclerosis; Animals; Brain; C9orf72 Protein; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Eye; GTPase-Activating Proteins; Mutation; Neurodegenerative Diseases; Nuclear Envelope; Nuclear Pore; Thiazoles

2019
Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2019, Volume: 15, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Autopsy; Brain; Female; Fluorine Radioisotopes; Humans; Magnetic Resonance Imaging; Male; Neurodegenerative Diseases; Neurofibrillary Tangles; Neuroimaging; Neuropathology; Plaque, Amyloid; Positron-Emission Tomography; Prospective Studies; Thiazoles

2019
Why and how protein aggregation has to be studied in vivo.
    Microbial cell factories, 2013, Feb-15, Volume: 12

    Topics: Amyloid; Benzothiazoles; Humans; Magnetic Resonance Spectroscopy; Molecular Chaperones; Neurodegenerative Diseases; Peptide Hydrolases; Proteins; Recombinant Fusion Proteins; Spectroscopy, Fourier Transform Infrared; Thiazoles

2013
Characterization of a single-chain variable fragment recognizing a linear epitope of aβ: a biotechnical tool for studies on Alzheimer's disease?
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Enzyme-Linked Immunosorbent Assay; Epitopes; Humans; Immunoglobulin G; Immunohistochemistry; Ligands; Mice; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Neurodegenerative Diseases; Permeability; Plasmids; Protein Binding; Sequence Alignment; Single-Chain Antibodies; Thiazoles

2013
Resveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathway.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Calcium; Cell Survival; Flow Cytometry; Gene Expression Regulation; Homeostasis; L-Lactate Dehydrogenase; Neurodegenerative Diseases; Neurons; PC12 Cells; Peptide Fragments; Rats; Resveratrol; rho-Associated Kinases; Signal Transduction; Sirtuin 1; Stilbenes; Tetrazolium Salts; Thiazoles

2013
Clinical profile of PiB-positive corticobasal syndrome.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Aged; Alzheimer Disease; Aniline Compounds; Carbon Radioisotopes; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Motor Activity; Neurodegenerative Diseases; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles

2013
Progressive apraxic agraphia with micrographia presenting as corticobasal syndrome showing extensive Pittsburgh compound B uptake.
    Journal of neurology, 2013, Volume: 260, Issue:8

    Topics: Aged; Agraphia; Aniline Compounds; Apolipoproteins E; Apraxias; Basal Ganglia Diseases; Brain; Cerebral Cortex; Cysteine; Disease Progression; Executive Function; Female; Handwriting; Humans; Image Processing, Computer-Assisted; Intelligence Tests; Neurodegenerative Diseases; Neurologic Examination; Neuropsychological Tests; Organotechnetium Compounds; Positron-Emission Tomography; Radiopharmaceuticals; Reading; Thiazoles; Tomography, Emission-Computed, Single-Photon

2013
Drug resistance confounding prion therapeutics.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-29, Volume: 110, Issue:44

    Topics: Animals; Brain; Cell Line; DNA Primers; Drug Discovery; Drug Resistance; Female; Humans; Immunoblotting; Luminescent Measurements; Mice; Neurodegenerative Diseases; Prions; Thiazoles

2013
Amyloid and neurodegeneration: converging and diverging paths.
    Neurology, 2013, Nov-12, Volume: 81, Issue:20

    Topics: Amyloid; Aniline Compounds; Cognition Disorders; Humans; Neurodegenerative Diseases; Positron-Emission Tomography; Thiazoles

2013
Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people.
    JAMA neurology, 2013, Volume: 70, Issue:12

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Biomarkers; Cognition Disorders; Cohort Studies; Community-Based Participatory Research; Cross-Sectional Studies; Female; Fluorodeoxyglucose F18; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated; Neurodegenerative Diseases; Neuropsychological Tests; Positron-Emission Tomography; Psychiatric Status Rating Scales; Thiazoles

2013
Diffusion tensor imaging comparison of progressive supranuclear palsy and corticobasal syndromes.
    Parkinsonism & related disorders, 2014, Volume: 20, Issue:5

    Topics: Aged; Aniline Compounds; Anisotropy; Brain; Diffusion Tensor Imaging; Female; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Neurodegenerative Diseases; Positron-Emission Tomography; Supranuclear Palsy, Progressive; Thiazoles; White Matter

2014
Deciphering aggregates, prefibrillar oligomers and protofibrils of cytochrome c.
    Amino acids, 2014, Volume: 46, Issue:8

    Topics: Anilino Naphthalenesulfonates; Benzothiazoles; Circular Dichroism; Cytochromes c; DNA Damage; Humans; Microscopy, Electron, Scanning; Neurodegenerative Diseases; Polyethylene Glycols; Protein Aggregates; Protein Conformation; Protein Folding; Proteostasis Deficiencies; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Thiazoles; Trifluoroethanol

2014
Measuring disease progression in corticobasal syndrome.
    Journal of neurology, 2014, Volume: 261, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aniline Compounds; Basal Ganglia; Cerebral Cortex; Cognition Disorders; Disease Progression; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurodegenerative Diseases; Neuropsychological Tests; Positron-Emission Tomography; Severity of Illness Index; Statistics, Nonparametric; Thiazoles

2014
Anti-inflammatory mechanisms of N-adamantyl-4-methylthiazol-2-amine in lipopolysaccharide-stimulated BV-2 microglial cells.
    International immunopharmacology, 2014, Volume: 22, Issue:1

    Topics: Adamantane; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Movement; Hydrogen Peroxide; Interleukin-1beta; Lipid Peroxidation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Microglia; NADPH Oxidases; Neurodegenerative Diseases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Thiazoles; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2014
Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders.
    British journal of pharmacology, 2014, Volume: 171, Issue:24

    Topics: AIDS Dementia Complex; Animals; Antineoplastic Agents; Cyclin-Dependent Kinase 5; Dasatinib; Erlotinib Hydrochloride; Flavonoids; HIV Envelope Protein gp120; In Vitro Techniques; Indoles; Lapatinib; Mice; Mice, Transgenic; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Protein Kinase Inhibitors; Purines; Pyrimidines; Pyrroles; Quinazolines; Rats; Roscovitine; Sunitinib; Thiazoles

2014
Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: a cross-sectional study.
    The Lancet. Neurology, 2014, Volume: 13, Issue:10

    Topics: Age Distribution; Aged; Aged, 80 and over; Alzheimer Disease; Amyloidosis; Aniline Compounds; Apolipoproteins E; Cognition; Cohort Studies; Cross-Sectional Studies; DNA; Educational Status; Female; Humans; Male; Middle Aged; Neurodegenerative Diseases; Neuropsychological Tests; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles; Verbal Learning

2014
Role of β-Amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment.
    JAMA neurology, 2015, Volume: 72, Issue:12

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloidosis; Aniline Compounds; Cognitive Dysfunction; Cohort Studies; Disease Progression; Female; Fluorodeoxyglucose F18; Gray Matter; Humans; Male; Neurodegenerative Diseases; Positron-Emission Tomography; Thiazoles

2015
Characterizing White Matter Tract Degeneration in Syndromic Variants of Alzheimer's Disease: A Diffusion Tensor Imaging Study.
    Journal of Alzheimer's disease : JAD, 2016, Volume: 49, Issue:3

    Topics: Aged; Alzheimer Disease; Aniline Compounds; Anisotropy; Aphasia, Primary Progressive; Case-Control Studies; Diffusion Tensor Imaging; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Nerve Fibers, Myelinated; Neurodegenerative Diseases; Neuropsychological Tests; Positron-Emission Tomography; Psychiatric Status Rating Scales; Retrospective Studies; Thiazoles; White Matter

2016
Amyloid deposition in semantic dementia: a positron emission tomography study.
    International journal of geriatric psychiatry, 2016, Volume: 31, Issue:9

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Case-Control Studies; Cerebral Cortex; Female; Frontotemporal Dementia; Humans; Male; Middle Aged; Neurodegenerative Diseases; Positron-Emission Tomography; Thiazoles

2016
[18F]AV-1451 tau-PET uptake does correlate with quantitatively measured 4R-tau burden in autopsy-confirmed corticobasal degeneration.
    Acta neuropathologica, 2016, Volume: 132, Issue:6

    Topics: Aniline Compounds; Autopsy; Basal Ganglia; Carbolines; Cerebral Cortex; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurodegenerative Diseases; Positron-Emission Tomography; tau Proteins; Thiazoles

2016
Effects of amyloid-beta peptides on hydrogen peroxide-metabolizing enzymes in rat brain in vivo.
    Free radical research, 2008, Volume: 42, Issue:6

    Topics: Amyloid beta-Peptides; Animals; Antioxidants; Benzothiazoles; Brain; Cytosol; Hydrogen Peroxide; Male; Mitochondria; Models, Biological; Neurodegenerative Diseases; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Thiazoles

2008
Acrolein, the toxic endogenous aldehyde, induces neurofilament-L aggregation.
    BMB reports, 2008, Sep-30, Volume: 41, Issue:9

    Topics: Acrolein; Animals; Benzothiazoles; Fluorescent Dyes; Free Radical Scavengers; Humans; Mice; Neurodegenerative Diseases; Neurofilament Proteins; Protein Carbonylation; Thiazoles

2008
Decylubiquinone increases mitochondrial function in synaptosomes.
    The Journal of biological chemistry, 2010, Mar-19, Volume: 285, Issue:12

    Topics: Animals; Antimycin A; Electron Transport; Female; Methacrylates; Mitochondria; Models, Biological; Neurodegenerative Diseases; Oxygen Consumption; Rats; Rats, Wistar; Rotenone; Synaptosomes; Thiazoles; Ubiquinone; Uncoupling Agents

2010
Critical role of interfaces and agitation on the nucleation of Abeta amyloid fibrils at low concentrations of Abeta monomers.
    Biochimica et biophysica acta, 2010, Volume: 1804, Issue:4

    Topics: Air; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Benzothiazoles; Brain Chemistry; Fluorescent Dyes; Humans; In Vitro Techniques; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Neurodegenerative Diseases; Peptide Fragments; Protein Binding; Protein Conformation; Protein Multimerization; Solutions; Spectrometry, Fluorescence; Thiazoles; Water

2010
11C-PiB PET ABri imaging in Worster-Drought syndrome (familial British dementia): a case report.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 19, Issue:2

    Topics: Aniline Compounds; Benzothiazoles; Dementia; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurodegenerative Diseases; Positron-Emission Tomography; Thiazoles

2010
The specificity of amyloid imaging in the diagnosis of neurodegenerative diseases.
    Neurobiology of aging, 2012, Volume: 33, Issue:6

    Topics: Amyloid; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Diagnostic Imaging; Humans; Neurodegenerative Diseases; Thiazoles

2012
Use of yeast as a system to study amyloid toxicity.
    Methods (San Diego, Calif.), 2011, Volume: 53, Issue:3

    Topics: Amyloid; Benzothiazoles; Centrifugation; Chromatography, Gel; Electrophoresis, Agar Gel; Microbial Viability; Microscopy, Fluorescence; Neurodegenerative Diseases; Organisms, Genetically Modified; Prions; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Staining and Labeling; Thiazoles

2011
Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy.
    Protein & cell, 2011, Volume: 2, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Substitution; Benzothiazoles; DNA-Binding Proteins; Humans; Mutation; Neurodegenerative Diseases; Protein Structure, Tertiary; Recombinant Proteins; RNA-Binding Protein FUS; Saccharomyces cerevisiae; Sarcosine; Thiazoles

2011
Interference of low-molecular substances with the thioflavin-T fluorescence assay of amyloid fibrils.
    Journal of peptide science : an official publication of the European Peptide Society, 2012, Volume: 18, Issue:1

    Topics: Amyloid; Amyloid beta-Peptides; Azure Stains; Benzothiazoles; Biological Assay; Diabetes Mellitus, Type 2; False Positive Reactions; Fluorescent Dyes; Humans; Insulin; Kinetics; Neurodegenerative Diseases; Protein Structure, Secondary; Spectrometry, Fluorescence; Tannins; Thiazoles

2012
Solid-state NMR reveals differences in the packing arrangements of peptide aggregates derived from the aortic amyloid polypeptide medin.
    Journal of peptide science : an official publication of the European Peptide Society, 2012, Volume: 18, Issue:1

    Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Antigens, Surface; Aorta; Benzothiazoles; Biomarkers; Diabetes Mellitus, Type 2; Humans; Magnetic Resonance Spectroscopy; Microscopy, Electron; Milk Proteins; Molecular Sequence Data; Neurodegenerative Diseases; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Thiazoles

2012
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation.
    Nature chemical biology, 2012, Feb-26, Volume: 8, Issue:4

    Topics: Acetylglucosamine; Adaptor Proteins, Signal Transducing; Alzheimer Disease; Animals; Carbohydrate Conformation; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Mice; Mice, Transgenic; N-Acetylglucosaminyltransferases; Neurodegenerative Diseases; Neurons; Phosphorylation; Pyrans; tau Proteins; Thiazoles

2012
Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury.
    Journal of neuroinflammation, 2012, Feb-28, Volume: 9

    Topics: Animals; Brain Injuries; Calcium-Binding Proteins; Cognition Disorders; Diffusion Tensor Imaging; Disease Models, Animal; Ectodysplasins; Encephalitis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glycine; Hippocampus; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Movement Disorders; Neurodegenerative Diseases; Neurons; Phenylacetates; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Immunologic; Receptors, Metabotropic Glutamate; Recovery of Function; Statistics, Nonparametric; Thiazoles; Time Factors

2012
Characterizing a neurodegenerative syndrome: primary progressive apraxia of speech.
    Brain : a journal of neurology, 2012, Volume: 135, Issue:Pt 5

    Topics: Aged; Aged, 80 and over; Aniline Compounds; Apraxias; Brain; Diffusion Magnetic Resonance Imaging; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Language Tests; Male; Middle Aged; Neurodegenerative Diseases; Neurologic Examination; Neuropsychological Tests; Positron-Emission Tomography; Speech Disorders; Thiazoles; Tomography, X-Ray Computed

2012
Detection of α-synuclein aggregates by fluorescence microscopy.
    Rejuvenation research, 2012, Volume: 15, Issue:2

    Topics: alpha-Synuclein; Benzothiazoles; Biomarkers; Circular Dichroism; Dopaminergic Neurons; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Models, Biological; Neurodegenerative Diseases; Parkinson Disease; Recombinant Proteins; Surface Properties; Temperature; Thiazoles

2012
Pleurotus giganteus (Berk.) Karunarathna & K.D. Hyde: Nutritional value and in vitro neurite outgrowth activity in rat pheochromocytoma cells.
    BMC complementary and alternative medicine, 2012, Jul-19, Volume: 12

    Topics: Animals; Biological Products; Dietary Carbohydrates; Dietary Fiber; Dose-Response Relationship, Drug; Fruiting Bodies, Fungal; Malaysia; MAP Kinase Signaling System; Nerve Growth Factor; Neurites; Neurodegenerative Diseases; Nutritive Value; Oncogene Protein v-akt; PC12 Cells; Phenols; Pheochromocytoma; Phosphatidylinositol 3-Kinases; Phytotherapy; Pleurotus; Potassium; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Triterpenes

2012
Deciphering structural intermediates and genotoxic fibrillar aggregates of albumins: a molecular mechanism underlying for degenerative diseases.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Acetonitriles; Albumins; Benzothiazoles; Circular Dichroism; Congo Red; Humans; Lymphocytes; Microscopy, Electron, Scanning; Neurodegenerative Diseases; Ovalbumin; Protein Structure, Secondary; Sodium Chloride; Spectroscopy, Fourier Transform Infrared; Thiazoles; X-Ray Diffraction

2013
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo.
    The Journal of biological chemistry, 2013, Mar-15, Volume: 288, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidogenic Proteins; Animals; Benzothiazoles; Caenorhabditis elegans; Hippocampus; Mice; Mice, Inbred C57BL; Models, Biological; Neurodegenerative Diseases; Neurons; Peptides; Prions; Protein Binding; Protein Structure, Tertiary; Surface Plasmon Resonance; Synapses; Thiazoles

2013
The truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates.
    The Journal of biological chemistry, 2013, Mar-29, Volume: 288, Issue:13

    Topics: Amino Acid Motifs; Amyloidogenic Proteins; Amyotrophic Lateral Sclerosis; Benzothiazoles; Chromatography; Circular Dichroism; Dimerization; DNA-Binding Proteins; DNA, Complementary; Frontotemporal Lobar Degeneration; Glutathione Transferase; Glycine; Humans; Neurodegenerative Diseases; Peptides; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Scattering, Radiation; Thiazoles; X-Rays

2013
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Nov-01, Volume: 22, Issue:21

    Topics: Amino Acid Substitution; Animals; Apoptosis; Benzothiazoles; Brain; Brain Chemistry; Cell Count; Disease Models, Animal; Homozygote; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Motor Neurons; Neurodegenerative Diseases; Paraparesis; Phenotype; Phosphorylation; Sarcosine; Solubility; Spinal Cord; tau Proteins; Thiazoles

2002
p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults.
    Neuromolecular medicine, 2003, Volume: 3, Issue:3

    Topics: Animals; Benzothiazoles; Brain; Cells, Cultured; DNA Damage; Etoposide; Membrane Potentials; Mice; Mitochondria; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxins; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Phosphorylation; Presynaptic Terminals; Reactive Oxygen Species; Synapsins; Synaptosomes; Thiazoles; Toluene; Tumor Suppressor Protein p53

2003
Nitration of tau protein is linked to neurodegeneration in tauopathies.
    The American journal of pathology, 2003, Volume: 163, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Ganglia; Benzothiazoles; Cell Line; Cerebral Cortex; Down Syndrome; Female; Fluorescent Dyes; Humans; Male; Middle Aged; Nerve Degeneration; Neurodegenerative Diseases; Neurofibrillary Tangles; Nitrates; Pick Disease of the Brain; tau Proteins; Tauopathies; Thiazoles; Tissue Distribution

2003
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases.
    The Journal of biological chemistry, 2004, Nov-05, Volume: 279, Issue:45

    Topics: Amyloid; Amyloid beta-Peptides; Benzothiazoles; Cell Membrane; Chromatography; Electrophysiology; Humans; Ions; Lipid Bilayers; Microscopy, Electron; Neurodegenerative Diseases; Peptides; Protein Conformation; Protein Folding; Spectrometry, Fluorescence; Thiazoles; Time Factors; Transfection

2004
An in vitro screening assay based on synthetic prion protein peptides for identification of fibril-interfering compounds.
    Analytical biochemistry, 2004, Oct-15, Volume: 333, Issue:2

    Topics: Amino Acid Sequence; Benzothiazoles; Drug Evaluation, Preclinical; Fluorescent Dyes; Gelatin; Humans; Models, Molecular; Molecular Sequence Data; Neurodegenerative Diseases; Neurofibrils; Peptide Fragments; Prions; Reproducibility of Results; Sensitivity and Specificity; Staining and Labeling; Tetracycline; Thiazoles; Time Factors

2004
Interaction of human stefin B in the prefibrillar oligomeric form with membranes. Correlation with cellular toxicity.
    The FEBS journal, 2005, Volume: 272, Issue:12

    Topics: Cell Membrane; Cystatin A; Cystatin B; Cystatins; Cysteine Proteinase Inhibitors; Fluoresceins; Humans; Lipid Bilayers; Membrane Lipids; Neuroblastoma; Neurodegenerative Diseases; Neurofibrillary Tangles; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Surface Properties; Tetrazolium Salts; Thiazoles; Toxicity Tests; Tumor Cells, Cultured

2005
Inducible neuronal expression of transgenic TGF-beta1 in vivo: dissection of short-term and long-term effects.
    The European journal of neuroscience, 2005, Volume: 22, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Apolipoproteins E; Benzothiazoles; Brain; Doxycycline; Gene Expression Regulation; Gene Silencing; Mice; Mice, Transgenic; Molecular Biology; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Plaque, Amyloid; Propionates; Thiazoles; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transgenes

2005
Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Dementia; Electron Spin Resonance Spectroscopy; Enzyme-Linked Immunosorbent Assay; Family Health; Humans; Hydrogen Peroxide; Microscopy, Atomic Force; Models, Statistical; Neurodegenerative Diseases; Oxidative Stress; Oxygen; Peptide Fragments; Peptides; Spin Trapping; Thiazoles; Time Factors; United Kingdom

2005
The Wnt signaling pathway as a target for the treatment of neurodegenerative disorders.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:1

    Topics: Animals; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Homeostasis; Humans; Indoles; Lithium Chloride; Maleimides; Models, Biological; Nervous System; Neurodegenerative Diseases; Pyridines; Pyrimidines; Signal Transduction; Thiazoles; Urea; Wnt Proteins

2006
Frontotemporal dementia: clinicopathological correlations.
    Annals of neurology, 2006, Volume: 59, Issue:6

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Benzothiazoles; Brain; Dementia; Diagnosis, Differential; Female; Humans; Immunohistochemistry; Inclusion Bodies; Male; Middle Aged; Neurodegenerative Diseases; Neuropsychological Tests; Tauopathies; Thiazoles; Ubiquitin

2006
Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons.
    Journal of neurochemistry, 2006, Volume: 98, Issue:4

    Topics: Adenosine Triphosphate; Amyloid beta-Peptides; Androstenes; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cells, Cultured; Cerebral Cortex; Cholesterol; Gas Chromatography-Mass Spectrometry; Glutathione; Lipid Peroxidation; Membrane Potentials; Mice; Neurodegenerative Diseases; Neurons; Oxidative Stress; Proteasome Endopeptidase Complex; Tetrazolium Salts; Thiazoles

2006
Conformation-dependent anti-amyloid oligomer antibodies.
    Methods in enzymology, 2006, Volume: 413

    Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Animals; Antibodies; Benzothiazoles; Circular Dichroism; Epitopes; Humans; Molecular Mimicry; Molecular Sequence Data; Neurodegenerative Diseases; Peptide Fragments; Protein Conformation; Protein Structure, Quaternary; Rabbits; Thiazoles

2006
Endogenous dopamine (DA) renders dopaminergic cells vulnerable to challenge of proteasome inhibitor MG132.
    Free radical research, 2008, Volume: 42, Issue:5

    Topics: alpha-Methyltyrosine; Animals; Cell Survival; Cysteine Proteinase Inhibitors; Dopamine; Leupeptins; Malondialdehyde; Mice; Neurodegenerative Diseases; Neurons; Parkinson Disease; PC12 Cells; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Tetrazolium Salts; Thiazoles

2008
Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments.
    FEBS letters, 1998, Nov-27, Volume: 440, Issue:1-2

    Topics: alpha-Synuclein; Amyloid; Apoptosis; Benzothiazoles; Biopolymers; Cell Nucleus; Cell Survival; Circular Dichroism; Humans; Microscopy, Electron; Mutation; Nerve Tissue Proteins; Neuroblastoma; Neurodegenerative Diseases; Neurons; Parkinson Disease; Peptides; Protein Structure, Secondary; Synucleins; Thiazoles; Tumor Cells, Cultured

1998
Multiple ligand interaction of alpha-synuclein produced various forms of protein aggregates in the presence of Abeta25-35, copper, and eosin.
    Brain research, 2001, Jul-20, Volume: 908, Issue:1

    Topics: alpha-Synuclein; Amyloid beta-Peptides; Benzothiazoles; Cells, Cultured; Copper; Eosine Yellowish-(YS); Fluorescent Dyes; Ligands; Microscopy, Electron; Nerve Tissue Proteins; Neurodegenerative Diseases; Peptide Fragments; Polymers; Protein Structure, Tertiary; Synucleins; Thiazoles

2001
Studies on the neuroprotective effect of the enantiomers of AR-A008055, a compound structurally related to clomethiazole, on MDMA ("ecstasy")-induced neurodegeneration in rat brain.
    Psychopharmacology, 2001, Volume: 157, Issue:1

    Topics: Animals; Body Temperature; Chlormethiazole; Male; Methylamines; N-Methyl-3,4-methylenedioxyamphetamine; Neurodegenerative Diseases; Neuroprotective Agents; Pentobarbital; Rats; Receptors, GABA-A; Stereoisomerism; Thiazoles

2001
Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau.
    Neurobiology of disease, 2001, Volume: 8, Issue:6

    Topics: Animals; Benzothiazoles; Brain; Cerebral Cortex; Coloring Agents; Congo Red; Disease Models, Animal; Female; Gene Expression Regulation; Hippocampus; Humans; Immunohistochemistry; Male; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Microscopy, Electron; Mutation, Missense; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurons; Protein Structure, Secondary; tau Proteins; Thiazoles; Transfection; Ubiquitin

2001
Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma.
    Journal of neuroscience research, 2002, Feb-15, Volume: 67, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Alzheimer Disease; Amyloid beta-Peptides; Anti-Bacterial Agents; Aristolochic Acids; Benzothiazoles; Bongkrekic Acid; Brain; Caspase Inhibitors; Caspases; Cell Death; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Humans; Neuroblastoma; Neurodegenerative Diseases; Neurons; Parkinson Disease; Peptide Fragments; Phenanthrenes; Pramipexole; Thiazoles; Tumor Cells, Cultured

2002
A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Amino Acid Sequence; Animals; Antimetabolites; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Differentiation; Cyclic AMP; DNA Replication; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Immunohistochemistry; L-Lactate Dehydrogenase; Molecular Sequence Data; Nerve Growth Factor; Neurodegenerative Diseases; PC12 Cells; Peptide Fragments; Peptides; Protein Precursors; Rats; Receptors, Glucagon; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Venoms

2002