Page last updated: 2024-08-21

thiazoles and Nerve Degeneration

thiazoles has been researched along with Nerve Degeneration in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.82)	18.7374
1990's	10 (18.18)	18.2507
2000's	34 (61.82)	29.6817
2010's	10 (18.18)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Georgopoulos, S; Klinakis, A; Paouri, E; Sesele, K; Thanopoulou, K; Tsefou, E	1
Cho, SW; Choi, J; Choi, SY; Hahn, HG; Han, AR; Kim, EA	1
Ames, D; Bourgeat, P; Ellis, KA; Harrington, K; Lim, YY; Martins, RN; Maruff, P; Masters, CL; Pietrzak, RH; Rembach, A; Rowe, CC; Salvado, O; Snyder, PJ; Villemagne, VL	1
Hasegawa, M; Higuchi, M; Hisanaga, SI; Imura, S; Masuda-Suzukake, M; Ono, M; Shimozawa, A; Takahara, D; Tarutani, A; Yanai, K	1
Du, Y; Fan, X; Le, W; Li, X; Luo, G; Yang, D	1
Drinkut, A; Falkenburger, BH; Gerhardt, E; Krenz, A; Schulz, JB	1
Horne, MK; Jarrott, B; Stanić, D; Sui, Y; Tomas, D	1
Achim, CL; Chana, G; Everall, IP; Grant, I; Hult, BJ; Lucero, GR; Masliah, E; Nguyen, TB; Tatro, ET	1
Acosta, O; Ames, D; Bourgeat, P; Chételat, G; Ellis, KA; Fripp, J; Martins, RN; Masters, CL; Ourselin, S; Pike, K; Raniga, P; Rowe, CC; Salvado, O; Szoeke, C; Villemagne, VL	1
Huang, W; Lei, H; Wang, X; Xu, W; Zhan, Y; Zhang, S	1
Bramanti, P; Cuzzocrea, S; Esposito, E; Meli, R; Paterniti, I	1
Alagille, D; Bogenpohl, JW; Delevich, K; Masilamoni, GJ; Smith, Y; Tamagnan, G; Votaw, JR; Wichmann, T	1
Asari, M; Awaya, T; Kimura, N; Matsubara, K; Noda, T; Ohkubo, T; Ohtaki, K; Omura, T; Ono, T; Sakaguchi, T; Shimizu, K; Suno, M; Tasaki, Y; Yamamoto, J	1
Agholme, L; Granseth, B; Hallbeck, M; Kurudenkandy, FR; Marcusson, J; Nath, S	1
Bergmans, P; Booij, J; Stoof, JC; van Royen, EA; Winogrodzka, A; Wolters, EC	1
Choi, DK; Jackson-Lewis, V; Przedborski, S; Teismann, P; Tieu, K; Vila, M; Wu, DC	1
Fleckenstein, AE; Hanson, GR; Rau, KS; Truong, JG	1
Bellmann, C; Giasson, BI; Horiguchi, T; Ischiropoulos, H; Lee, VM; LightFoot, R; Richter-Landsberg, C; Trojanowski, JQ; Uryu, K	1
Biglieri, M; Bisaglia, M; Mancini, F; Milanese, C; Russo, C; Schettini, G; Venezia, V	1
May, FJ; Monteith, GR; Roberts-Thomson, SJ; Robinson, JA; Smith, SA; Venkata, NG	1
Barger, SW; Jiang, S; Sims, TJ; Wu, SZ	1
Braga, AL; Centurião, FB; Corte, CL; Emanuelli, T; Paixão, MW; Rocha, JB; Zeni, G	1
Arendt, T; Brückner, MK; Gärtner, U; Gebhardt, R; Gruschka, H; Seeger, G; Ueberham, E; Ueberham, U	1
Avila, J; Engel, T; Gómez-Ramos, P; Hernández, F; Lucas, JJ; Moran, MA	1
de Chaves, EI; Saavedra, L; Song, MS	1
Chechlacz, M; Gilliams-Francis, K; Lamonica, K; Lin, SL; Liu, J; Naegele, JR; Navarro-Quiroga, I; Neema, M	1
Bezard, E; Gerlach, I; Gross, CE; Jork, R; Moratalla, R	1
Anderson, S; Illanes, O; Jessen, BA; Niesman, M; Zwick, L	1
Johnson, KM; Lei, G; Xia, Y	1
De Felice, FG; Ferreira, ST; Forny-Germano, L; Houzel, JC; Martinez, AM; Saraiva, LM; Sebollela, A; Vieira, MN	1
Bian, GL; Chen, LW; Wang, YQ; Wei, LC; Yung, KL	1
Barreto, G; Bertolino, LA; Capani, F; Giraldez, LD; Madureira de Oliveria, D; Saraceno, E; Valverde G De Andrade, D	1
Battistin, L; Bellucci, A; Collo, G; Missale, C; Sarnico, I; Spano, P	1
Arendt, T; Bigl, V; Brückner, MK; Marcova, L	1
Bousseau, A; Couratier, P; Esclaire, F; Hugon, J; Sindou, P; Yardin, C	1
Greenberg, SG; Nelson, PT; Saper, CB	1
Ben-Ari, Y; Charriaut-Marlangue, C; Dessi, F	1
Cotman, CW; Korotzer, AR; Pike, CJ	1
Gómez-Ramos, P; Morán, MA; Navarro, C; Probst, A	1
Althaus, JS; Andrus, PK; Hall, ED; Oostveen, JA; VonVoigtlander, PF	1
Brouillet, E; Guyot, MC; Hantraye, P; Mary, V; Palfi, S; Peschanski, M; Riche, D; Stutzmann, JM; Wahl, F	1
Cross, AJ; Green, AR; Jones, JA; Misra, A; Murray, TK; Snape, MF	1
Bales, KR; Fagan, AM; Holtzman, DM; Mackey, B; McKeel, D; Olney, J; Parsadanian, M; Paul, SM; Sartorius, LJ; Tenkova, T; Wozniak, D	1
Carvey, PM; Chen, EY; Ling, ZD; Lipton, JW; Ma, SY; Robie, HC; Tong, CW; Vu, TQ	1
Kaneko, I; Kubo, T; Morimoto, K	1
Koinig, H; Rueda, C; Vornik, V; Zornow, MH	1
Duff, K; La Francois, J; Matsuoka, Y; Picciano, M	1
Malecki, EA	1
Dickson, TC; Vickers, JC	1
Dixon, CE; Horváth, E; Kline, AE; Marion, DW; Yu, J	1
Duda, JE; Giasson, BI; Golbe, LI; Lee, VM; Mabon, ME; Miller, DC; Trojanowski, JQ	1
Banga, JD; Hendriksen, PH; Oey, PL; van Dam, PS; Wieneke, GH	1
Van Hoesen, GW; Vogt, BA; Vogt, LJ	1
Défossez, A; Delacourte, A	1

Reviews

2 review(s) available for thiazoles and Nerve Degeneration

Article	Year
COX-2 and neurodegeneration in Parkinson's disease. Annals of the New York Academy of Sciences, 2003, Volume: 991 Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Humans; Isoenzymes; Meloxicam; Membrane Proteins; Mice; MPTP Poisoning; Nerve Degeneration; Parkinson Disease; Prostaglandin-Endoperoxide Synthases; Substantia Nigra; Thiazines; Thiazoles	2003
[Neurotoxicity of beta-amyloid]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2000, Volume: 115, Issue:2 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cells, Cultured; Excitatory Amino Acids; Hippocampus; Humans; Nerve Degeneration; Oxidation-Reduction; Rats; Solubility; Stereoisomerism; Tetrazolium Salts; Thiazoles	2000

Trials

2 trial(s) available for thiazoles and Nerve Degeneration

Article	Year
Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression. JAMA, 2002, Apr-03, Volume: 287, Issue:13 Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain; Cocaine; Disease Progression; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Randomized Controlled Trials as Topic; Regression Analysis; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	2002
Antihypoxic treatment at an early stage of diabetic neuropathy: an electrophysiological study with sabeluzole. Acta neurologica Scandinavica, 1992, Volume: 86, Issue:5 Topics: Adult; Aged; Autonomic Nervous System Diseases; Cell Hypoxia; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Electromyography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nerve Degeneration; Neurologic Examination; Peripheral Nerves; Piperidines; Sensory Thresholds; Synaptic Transmission; Thiazoles	1992

Article

Year

Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression.

JAMA, 2002, Apr-03, Volume: 287, Issue:13

Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain; Cocaine; Disease Progression; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Randomized Controlled Trials as Topic; Regression Analysis; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome

2002

Antihypoxic treatment at an early stage of diabetic neuropathy: an electrophysiological study with sabeluzole.

Acta neurologica Scandinavica, 1992, Volume: 86, Issue:5

Topics: Adult; Aged; Autonomic Nervous System Diseases; Cell Hypoxia; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Electromyography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nerve Degeneration; Neurologic Examination; Peripheral Nerves; Piperidines; Sensory Thresholds; Synaptic Transmission; Thiazoles

1992

Other Studies

51 other study(ies) available for thiazoles and Nerve Degeneration

Article	Year
Conditional inactivation of nicastrin restricts amyloid deposition in an Alzheimer's disease mouse model. Aging cell, 2013, Volume: 12, Issue:6 Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzothiazoles; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Gliosis; Humans; Integrases; Membrane Glycoproteins; Mice; Mice, Transgenic; Nerve Degeneration; Neurons; Phenotype; Presenilin-1; Thiazoles	2013
Anti-oxidative and anti-inflammatory effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride on glutamate-induced neurotoxicity in rat brain. Neurotoxicology, 2013, Volume: 38 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Brain; Calcium; Caspase 3; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Interferon-gamma; Lipid Peroxidation; Male; Membrane Potentials; NADPH Oxidases; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Reactive Oxygen Species; Thiazoles; Tumor Necrosis Factor-alpha	2013
Relationships between performance on the Cogstate Brief Battery, neurodegeneration, and Aβ accumulation in cognitively normal older adults and adults with MCI. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2015, Volume: 30, Issue:1 Topics: Aged; Aged, 80 and over; Aging; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Atrophy; Carbon Isotopes; Cognitive Dysfunction; Female; Hippocampus; Humans; Linear Models; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Middle Aged; Nerve Degeneration; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles; Time Factors	2015
Propagation of pathological α-synuclein in marmoset brain. Acta neuropathologica communications, 2017, Feb-02, Volume: 5, Issue:1 Topics: alpha-Synuclein; Animals; Benzothiazoles; Brain; Callithrix; Female; Immunohistochemistry; Lewy Bodies; Microglia; Nerve Degeneration; Neurons; Parkinsonian Disorders; Protein Aggregation, Pathological; Recombinant Proteins; Sequence Homology, Amino Acid; Thiazoles; Tyrosine 3-Monooxygenase	2017
c-Jun N-terminal kinase mediates lactacystin-induced dopamine neuron degeneration. Journal of neuropathology and experimental neurology, 2008, Volume: 67, Issue:10 Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Line; Chromatography, High Pressure Liquid; Cysteine Proteinase Inhibitors; Cytochromes c; Dopamine; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Substantia Nigra; Tetrazolium Salts; Thiazoles	2008
Aggregate formation and toxicity by wild-type and R621C synphilin-1 in the nigrostriatal system of mice using adenoviral vectors. Journal of neurochemistry, 2009, Volume: 108, Issue:1 Topics: Adenoviridae; Animals; Arginine; Benzothiazoles; Carrier Proteins; Corpus Striatum; Cysteine; Gene Expression; Genetic Vectors; Green Fluorescent Proteins; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Substantia Nigra; Thiazoles; Tyrosine 3-Monooxygenase	2009
Meloxicam reduces lipopolysaccharide-induced degeneration of dopaminergic neurons in the rat substantia nigra pars compacta. Neuroscience letters, 2009, Aug-28, Volume: 460, Issue:2 Topics: Animals; CD11b Antigen; Cyclooxygenase Inhibitors; Disease Models, Animal; Dopamine; Lipopolysaccharides; Male; Meloxicam; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Substantia Nigra; Thiazines; Thiazoles; Tyrosine 3-Monooxygenase	2009
Glycogen synthase kinase-3beta (GSK-3beta) inhibitors AR-A014418 and B6B3O prevent human immunodeficiency virus-mediated neurotoxicity in primary human neurons. Journal of neurovirology, 2009, Volume: 15, Issue:5-6 Topics: AIDS Dementia Complex; Caspase 3; Caspase 7; Cells, Cultured; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; L-Lactate Dehydrogenase; Macrophages; Necrosis; Nerve Degeneration; Neurons; Oximes; Thiazoles; Urea	2009
Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia. Neurology, 2010, Jan-12, Volume: 74, Issue:2 Topics: Age Factors; Aged; Aged, 80 and over; Aging; Algorithms; Amyloid beta-Peptides; Aniline Compounds; Atrophy; Biomarkers; Brain Mapping; Carbon Radioisotopes; Cohort Studies; Disease Progression; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neocortex; Nerve Degeneration; Plaque, Amyloid; Positron-Emission Tomography; Severity of Illness Index; Temporal Lobe; Thiazoles	2010
Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons. Journal of neuroscience research, 2010, Nov-01, Volume: 88, Issue:14 Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Benzothiazoles; CA1 Region, Hippocampal; Creatine; Disease Models, Animal; Down-Regulation; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Nerve Degeneration; Plaque, Amyloid; Presenilin-1; Pyramidal Cells; Thiazoles	2010
GW0742, a high-affinity PPAR-δ agonist, mediates protection in an organotypic model of spinal cord damage. Spine, 2012, Jan-15, Volume: 37, Issue:2 Topics: Animals; Mice; Models, Biological; Nerve Degeneration; Neuroprotective Agents; Organ Culture Techniques; PPAR delta; Protein Isoforms; Spinal Cord; Spinal Cord Injuries; Thiazoles	2012
Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys. Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Brain; Brain Mapping; Calbindins; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Fluorine Radioisotopes; Macaca mulatta; MPTP Poisoning; Nerve Degeneration; Neurons; Norepinephrine; Nortropanes; Positron-Emission Tomography; Protein Binding; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; S100 Calcium Binding Protein G; Thiazoles; Tyrosine 3-Monooxygenase	2011
Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model. Neuroscience letters, 2012, Jul-11, Volume: 521, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Hypokinesia; Male; Meloxicam; Mesencephalon; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Parkinson Disease; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Thiazines; Thiazoles; Tyrosine 3-Monooxygenase	2012
Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Jun-27, Volume: 32, Issue:26 Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Cell Communication; Cell Differentiation; Cells, Cultured; Coculture Techniques; Dendrites; Dose-Response Relationship, Drug; Endocytosis; Exocytosis; Female; Green Fluorescent Proteins; Heterocyclic Compounds, 3-Ring; Hippocampus; Humans; Lysosomal-Associated Membrane Protein 2; Male; Membrane Glycoproteins; Microinjections; Microscopy, Electron, Transmission; Neocortex; Nerve Degeneration; Nerve Tissue Proteins; Neuroblastoma; Neuroglia; Neurons; Patch-Clamp Techniques; Peptide Fragments; rab5 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Rhodamines; Synaptic Transmission; Tetrazolium Salts; Thiazoles; Time Factors; Transfection	2012
[(123)I]beta-CIT SPECT is a useful method for monitoring dopaminergic degeneration in early stage Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry, 2003, Volume: 74, Issue:3 Topics: Antiparkinson Agents; Benzothiazoles; Caudate Nucleus; Cocaine; Corpus Striatum; Disease Progression; Female; Humans; Male; Nerve Degeneration; Parkinson Disease; Pergolide; Pramipexole; Putamen; Radiopharmaceuticals; Receptors, Dopamine D2; Reproducibility of Results; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	2003
Pramipexole increases vesicular dopamine uptake: implications for treatment of Parkinson's neurodegeneration. European journal of pharmacology, 2003, Aug-08, Volume: 474, Issue:2-3 Topics: Animals; Benzothiazoles; Corpus Striatum; Dopamine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Degeneration; Neuropeptides; Parkinson Disease; Pramipexole; Rats; Rats, Sprague-Dawley; Synaptic Vesicles; Thiazoles; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins	2003
Nitration of tau protein is linked to neurodegeneration in tauopathies. The American journal of pathology, 2003, Volume: 163, Issue:3 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Ganglia; Benzothiazoles; Cell Line; Cerebral Cortex; Down Syndrome; Female; Fluorescent Dyes; Humans; Male; Middle Aged; Nerve Degeneration; Neurodegenerative Diseases; Neurofibrillary Tangles; Nitrates; Pick Disease of the Brain; tau Proteins; Tauopathies; Thiazoles; Tissue Distribution	2003
alpha-Glycerylphosphorylethanolamine rescues astrocytes from mitochondrial impairment and oxidative stress induced by amyloid beta-peptides. Neurochemistry international, 2004, Volume: 44, Issue:3 Topics: Amyloid beta-Peptides; Animals; Astrocytes; Cell Membrane; Cells, Cultured; Gliosis; Lipid Peroxidation; Membrane Fluidity; Membrane Potentials; Microscopy, Confocal; Mitochondria; Nerve Degeneration; Oxidative Stress; Peptide Fragments; Phosphatidylethanolamines; Rats; Tetrazolium Salts; Thiazoles	2004
Effect of the peroxisome proliferator-activated receptor beta activator GW0742 in rat cultured cerebellar granule neurons. Journal of neuroscience research, 2004, Jul-15, Volume: 77, Issue:2 Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebellum; L-Lactate Dehydrogenase; Nerve Degeneration; Neurons; Neurotoxins; Potassium Deficiency; Proto-Oncogene Proteins c-jun; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Transcription Factors	2004
Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists. Journal of neuroscience research, 2005, Mar-01, Volume: 79, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Calcium; Cell Death; Cells, Cultured; Culture Media, Conditioned; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; Kynurenic Acid; Microtubule-Associated Proteins; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schwann Cells; Tetrazolium Salts; Thiazoles; Time Factors	2005
Effect of ebselen and organochalcogenides on excitotoxicity induced by glutamate in isolated chick retina. Brain research, 2005, Mar-28, Volume: 1039, Issue:1-2 Topics: Animals; Azoles; Benzene Derivatives; Calcium; Calcium Channels; Chalcogens; Chick Embryo; Dose-Response Relationship, Drug; Glutamic Acid; Isoindoles; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Organometallic Compounds; Organoselenium Compounds; Retina; Tellurium; Tetrazolium Salts; Thiazoles	2005
Inducible neuronal expression of transgenic TGF-beta1 in vivo: dissection of short-term and long-term effects. The European journal of neuroscience, 2005, Volume: 22, Issue:1 Topics: Animals; Anti-Bacterial Agents; Apolipoproteins E; Benzothiazoles; Brain; Doxycycline; Gene Expression Regulation; Gene Silencing; Mice; Mice, Transgenic; Molecular Biology; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Plaque, Amyloid; Propionates; Thiazoles; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transgenes	2005
Cooexpression of FTDP-17 tau and GSK-3beta in transgenic mice induce tau polymerization and neurodegeneration. Neurobiology of aging, 2006, Volume: 27, Issue:9 Topics: Animals; Benzothiazoles; Biomarkers; Blotting, Western; Dentate Gyrus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunohistochemistry; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Nerve Degeneration; Neurofilament Proteins; Phosphorylation; tau Proteins; Thiazoles	2006
Apoptosis is secondary to non-apoptotic axonal degeneration in neurons exposed to Abeta in distal axons. Neurobiology of aging, 2006, Volume: 27, Issue:9 Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Antidotes; Apoptosis; Axons; Blotting, Western; Calcium-Binding Proteins; Calpain; Cells, Cultured; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Nerve Degeneration; Nerve Growth Factor; Neurons; Peptide Fragments; Prosencephalon; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Tetrazolium Salts; Thiazoles	2006
DNA damage and nonhomologous end joining in excitotoxicity: neuroprotective role of DNA-PKcs in kainic acid-induced seizures. Hippocampus, 2005, Volume: 15, Issue:8 Topics: Animals; Benzothiazoles; Cell Death; Cells, Cultured; DNA Damage; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Entorhinal Cortex; Excitatory Amino Acid Agonists; Heterozygote; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mitochondria; Nerve Degeneration; Neurons; Nuclear Proteins; Seizures; Thiazoles; Toluene; Tumor Suppressor Protein p53	2005
5-HT1A receptor agonist-mediated protection from MPTP toxicity in mouse and macaque models of Parkinson's disease. Neurobiology of disease, 2006, Volume: 23, Issue:1 Topics: Animals; Benzopyrans; Brain; In Situ Hybridization; Macaca; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Receptor, Serotonin, 5-HT1A; Serotonin Receptor Agonists; Thiazoles; Tyrosine 3-Monooxygenase	2006
Retinal and peripheral nerve toxicity induced by the administration of a pan-cyclin dependent kinase (cdk) inhibitor in mice. Toxicologic pathology, 2006, Volume: 34, Issue:3 Topics: Animals; Apoptosis; Benzamides; Cyclin-Dependent Kinases; Enzyme Inhibitors; Female; In Situ Nick-End Labeling; Male; Mice; Nerve Degeneration; Peripheral Nervous System; Peripheral Nervous System Diseases; Retina; Retinal Diseases; Sciatic Nerve; Thiazoles	2006
The role of Akt-GSK-3beta signaling and synaptic strength in phencyclidine-induced neurodegeneration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; L-Lactate Dehydrogenase; Nerve Degeneration; Oncogene Protein v-akt; Phencyclidine; Pregnancy; Prosencephalon; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Synapses; Tetrazolium Salts; Thiazoles; Time Factors	2008
Soluble oligomers from a non-disease related protein mimic Abeta-induced tau hyperphosphorylation and neurodegeneration. Journal of neurochemistry, 2007, Volume: 103, Issue:2 Topics: Amyloid beta-Peptides; Animals; Benzothiazoles; Blotting, Western; Cell Survival; Chickens; Chromatography, Gel; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Epitopes; Female; Fluorescent Antibody Technique; Fluorescent Dyes; Microscopy, Electron; Muramidase; Nephelometry and Turbidimetry; Nerve Degeneration; Neurons; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Rats, Wistar; tau Proteins; Thiazoles	2007
Neurokinin-3 peptide instead of neurokinin-1 synergistically exacerbates kainic acid-inducing degeneration of neurons in the substantia nigra of mice. Journal of neurochemistry, 2008, Volume: 105, Issue:1 Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Drug Synergism; Fluoresceins; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Neurons; Organic Chemicals; Peptide Fragments; Pyrrolidonecarboxylic Acid; Quinolines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Substantia Nigra; Tetrazolium Salts; Thiazoles	2008
Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells. Brain research, 2008, Mar-10, Volume: 1198 Topics: Apoptosis; Cell Line, Tumor; Cell Shape; Cell Survival; Cytoprotection; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Microscopy, Electron, Transmission; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Plant Extracts; Rotenone; Tetrazolium Salts; Thiazoles	2008
Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation. Journal of neurochemistry, 2008, Volume: 106, Issue:2 Topics: alpha-Synuclein; Analysis of Variance; Animals; Benzothiazoles; Cell Death; Cells, Cultured; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Embryo, Mammalian; Formazans; Gene Expression Regulation; Glucose; Mesencephalon; Mice; Mitochondria; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Protein Transport; Receptors, Dopamine D2; Tetrazolium Salts; Thiazoles	2008
Dendritic reorganisation in the basal forebrain under degenerative conditions and its defects in Alzheimer's disease. II. Ageing, Korsakoff's disease, Parkinson's disease, and Alzheimer's disease. The Journal of comparative neurology, 1995, Jan-09, Volume: 351, Issue:2 Topics: Adult; Aged; Aging; Alcohol Amnestic Disorder; Alzheimer Disease; Benzothiazoles; Cell Count; Dendrites; Female; Fluorescent Dyes; Histocytochemistry; Humans; Male; Middle Aged; Nerve Degeneration; Neuronal Plasticity; Parkinson Disease; Prosencephalon; Staining and Labeling; Thiazoles	1995
Prevention of HIV coat protein (gp120) toxicity in cortical cell cultures by riluzole. Journal of the neurological sciences, 1994, Volume: 126, Issue:2 Topics: Animals; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; HIV Envelope Protein gp120; HIV-1; Nerve Degeneration; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Riluzole; Thiazoles	1994
Neurofibrillary tangles in the cerebral cortex of sheep. Neuroscience letters, 1994, Mar-28, Volume: 170, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antigens; Benzothiazoles; Cerebral Cortex; Immunohistochemistry; Nerve Degeneration; Nerve Tissue Proteins; Neurofibrillary Tangles; Neurofibrils; Sheep; Silver Staining; tau Proteins; Thiazoles	1994
Riluzole prevents anoxic injury in cultured cerebellar granule neurons. European journal of pharmacology, 1993, Dec-07, Volume: 250, Issue:2 Topics: Animals; Cells, Cultured; Cerebellum; Hypoxia, Brain; Nerve Degeneration; Neurons; Rats; Riluzole; Synaptic Transmission; Thiazoles	1993
beta-Amyloid peptides induce degeneration of cultured rat microglia. Brain research, 1993, Oct-08, Volume: 624, Issue:1-2 Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Cell Count; Cell Survival; Cells, Cultured; Coloring Agents; Microglia; Nerve Degeneration; Rats; Tetrazolium Salts; Thiazoles; Time Factors	1993
Alzheimer's disease-type neurofibrillary degeneration in verrucose dysplasias of the cerebral cortex. Acta neuropathologica, 1995, Volume: 90, Issue:4 Topics: Aged; Alzheimer Disease; Benzothiazoles; Cerebral Cortex; Cholinesterases; Female; Fluorescent Dyes; Humans; Immunohistochemistry; Male; Nerve Degeneration; Neurofibrillary Tangles; tau Proteins; Thiazoles; Tissue Fixation	1995
Neuroprotective effects of the dopamine D2/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons. Brain research, 1996, Dec-02, Volume: 742, Issue:1-2 Topics: Animals; Benzothiazoles; Brain Ischemia; Corpus Striatum; Dopamine Agonists; Dose-Response Relationship, Drug; Gerbillinae; Male; Methamphetamine; Nerve Degeneration; Pramipexole; Substantia Nigra; Thiazoles	1996
Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration. Experimental neurology, 1997, Volume: 146, Issue:1 Topics: Acetylcholinesterase; Animals; Antiparkinson Agents; Apomorphine; Caudate Nucleus; Corpus Striatum; Movement Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Papio; Parkinson Disease, Secondary; Propionates; Putamen; Riluzole; Thiazoles	1997
The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites. British journal of pharmacology, 2000, Volume: 129, Issue:1 Topics: Animals; Brain; Brain Ischemia; Chlormethiazole; Gerbillinae; Hypnotics and Sedatives; Male; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Thiazoles	2000
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America, 2000, Mar-14, Volume: 97, Issue:6 Topics: Alzheimer Disease; Animals; Apolipoproteins E; Benzothiazoles; Disease Models, Animal; Genetic Predisposition to Disease; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Nerve Degeneration; Neurites; Plaque, Amyloid; Protein Isoforms; Thiazoles; Time Factors	2000
Pramipexole attenuates the dopaminergic cell loss induced by intraventricular 6-hydroxydopamine. Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:2 Topics: Animals; Benzothiazoles; Cell Count; Cell Death; Dopamine; Dopamine Agonists; Male; Neostriatum; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Pramipexole; Rats; Rats, Sprague-Dawley; Substantia Nigra; Thiazoles	2000
Lubeluzole inhibits accumulation of extracellular glutamate in the hippocampus during transient global cerebral ischemia. Brain research, 2001, Apr-20, Volume: 898, Issue:2 Topics: Action Potentials; Animals; Body Temperature; Brain Ischemia; Cardiovascular Physiological Phenomena; Extracellular Space; Glutamic Acid; Hippocampus; Microdialysis; Nerve Degeneration; Neurons; Neuroprotective Agents; Piperidines; Rabbits; Reperfusion Injury; Respiratory Physiological Phenomena; Thiazoles	2001
Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease. Neuroscience, 2001, Volume: 104, Issue:3 Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Immunohistochemistry; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Neurofibrillary Tangles; Oxidative Stress; Thiazoles; Tyrosine	2001
Manganese toxicity is associated with mitochondrial dysfunction and DNA fragmentation in rat primary striatal neurons. Brain research bulletin, 2001, May-15, Volume: 55, Issue:2 Topics: Animals; Cells, Cultured; Coloring Agents; Convulsants; Corpus Striatum; DNA Fragmentation; Electron Transport Complex II; Fetus; Manganese; Manganese Poisoning; Membrane Potentials; Mice; Microtubule-Associated Proteins; Mitochondria; Multienzyme Complexes; Nerve Degeneration; Neurons; Neurotoxins; Nitro Compounds; Oxidoreductases; Propionates; Rats; Rats, Wistar; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles	2001
The morphological phenotype of beta-amyloid plaques and associated neuritic changes in Alzheimer's disease. Neuroscience, 2001, Volume: 105, Issue:1 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Cerebral Cortex; Fluorescent Dyes; Humans; Immunohistochemistry; Microscopy, Confocal; Nerve Degeneration; Neurites; Neurofilament Proteins; Phenotype; Plaque, Amyloid; tau Proteins; Thiazoles	2001
The selective 5-HT(1A) receptor agonist repinotan HCl attenuates histopathology and spatial learning deficits following traumatic brain injury in rats. Neuroscience, 2001, Volume: 106, Issue:3 Topics: Animals; Benzopyrans; Body Temperature; Brain; Brain Injuries; Cognition; Cognition Disorders; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Nerve Degeneration; Neurons; Neuroprotective Agents; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Thiazoles; Vestibular Nuclei	2001
Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred. Acta neuropathologica, 2002, Volume: 104, Issue:1 Topics: Adult; alpha-Synuclein; Archives; Benzothiazoles; Brain; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Male; Microscopy, Immunoelectron; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Parkinson Disease; Synucleins; tau Proteins; Thiazoles	2002
Laminar distribution of neuron degeneration in posterior cingulate cortex in Alzheimer's disease. Acta neuropathologica, 1990, Volume: 80, Issue:6 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Benzothiazoles; Cerebral Cortex; Female; Humans; Male; Middle Aged; Nerve Degeneration; Neurons; Staining and Labeling; Thiazoles	1990
Transformation of degenerating neurofibrils into amyloid substance in Alzheimer's disease: histochemical and immunohistochemical studies. Journal of the neurological sciences, 1987, Volume: 81, Issue:1 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Benzothiazoles; Brain; Histocytochemistry; Humans; Immunohistochemistry; Nerve Degeneration; Neurofibrils; Staining and Labeling; Thiazoles	1987