Page last updated: 2024-08-21

thiazoles and Hyperuricemia

thiazoles has been researched along with Hyperuricemia in 100 studies

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's31 (31.00)29.6817
2010's66 (66.00)24.3611
2020's3 (3.00)2.80

Authors

AuthorsStudies
Becker, MA; Borer, JS; Castillo, M; Gorelick, PB; Gunawardhana, L; Hunt, B; Saag, KG; Whelton, A; White, WB1
Bao, Z; Gao, J; Li, Q; Lin, F; Mao, Q; Shen, C; Sun, M; Wang, H; Wang, S; Zhang, B1
Jatuworapruk, K; Lertnawapan, R1
Von Zingel, M1
Hosoya, T; Kobayashi, S; Ogura, M1
Hata, H; Hata, M; Nakata, K; Sezai, A; Shiono, M; Soma, M; Wakui, S; Yoshitake, I1
Beard, SM; Nuki, G; Pearson, IV; von Scheele, BG1
Ohno, I1
Murasawa, T; Ohno, D; Otsuka, T; Sakai, Y; Sato, N; Tsuruoka, S1
Hasegawa, K; Hiramitsu, S; Ishiguro, Y; Ishii, J; Kani, A; Kato, H; Kato, K; Kato, Y; Kimura, H; Matsubara, S; Matsubara, Y; Matsuyama, H; Mori, K; Noba, M; Shino, K; Tokuda, M; Uchiyama, T; Uemura, A; Yamada, K; Yoshida, S1
Bakris, GL; Doghramji, PP; Keenan, RT; Silber, SH1
Ehteshami-Afshar, A; Faruque, LI; Homik, J; Tjosvold, L; Tonelli, M; Wiebe, N1
Berns, JS; Wilson, FP1
Hayakawa, H; Hosoya, T; Iimuro, S; Imai, N; Inaba, M; Itoh, S; Kimura, K; Kuwabara, M; Makino, H; Matsuo, S; Ohno, I; Shibagaki, Y; Tomino, Y; Uchida, S; Yamamoto, T1
Bao, C; Du, H; Gu, J; Huang, A; Huang, X; Jiang, L; Li, J; Li, X; Li, Z; Liu, Y; Zhang, Y; Zhang, Z; Zhao, D; Zhu, P; Zuo, X1
Baumgartner, S; Fleischmann, R; Hingorani, V; Kerr, B; Manhard, K; Miner, JN; Polvent, E; Quart, B; Shen, Z; Suster, M; Yeh, LT1
Hara, T; Hayashida, Y; Inui, M; Kakehi, Y; Kohno, M; Moriwaki, K; Nishijima, Y; Nishiyama, A; Sofue, T; Ueda, N1
Bae, EJ; Chang, SH; Cho, HS; Jang, HN; Kang, Y; Kim, MJ; Park, DJ; Yun, S1
Aoki, T; Hishida, M; Maekawa, M; Morinaga, T; Tamai, H; Tomida, H1
Fuchinoue, S; Nakajima, I; Teraoka, S; Tojimbara, T; Yashima, J1
Espinoza, LR; Grewal, HK; Martinez, JR1
Bocale, R; Desideri, G; Ferri, C; Grassi, D; Pontremoli, R1
Becker, MA; Chaichian, Y; Chohan, S1
Banse, C; Fardellone, P; Paccou, J1
Jansen, TL1
Ohya, M; Shigematsu, T1
Itabashi, M; Mochizuki, T; Moriyama, T; Nitta, K; Takei, T; Tsuchiya, K; Tsuruta, Y1
Hayashi, H; Hayashi, T; Hikosaka, S; Mizuno, T; Murase, M; Nagamatsu, T; Shimabukuro, Y; Takahashi, K; Yamada, S; Yuzawa, Y1
Brucato, AL; Corrao, S; Di Corato, P; Djade, CD; Franchi, C; Ghidoni, S; Mannucci, PM; Marcucci, M; Marengoni, A; Nobili, A; Pasina, L; Salerno, F; Tettamanti, M1
Zelicoff, A1
Asano, T; Fujishiro, M; Fukushima, T; Kamata, H; Kanaoka, R; Katasako, A; Kushiyama, A; Matsunaga, Y; Mori, K; Nakatsu, Y; Sakoda, H; Seno, Y; Yamamotoya, T1
Jang, JW; Jung, SH; Kim, GT; Kim, TH; Park, H; Park, WS; Song, JU1
Fujimaki, K; Fujisaki, T; Gemba, K; Goto, T; Kaneko, M; Kawai, Y; Kiguchi, T; Kirito, K; Maemondo, M; Nakajima, A; Okamoto, M; Takeda, K; Tamura, K; Ueda, T1
Bakinde, N; Mome, R1
Filiopoulos, V; Hadjiyannakos, D; Vlassopoulos, D1
Sircar, D1
Andrés, M; Gil, S; Pascual, E; Quilis, N; Ranieri, L; Vela, P1
Chen, LX; Schumacher, HR1
Hair, PI; Keating, GM; McCormack, PL1
Schlesinger, N2
Edwards, NL2
Becker, MA; Hunt, B; Joseph-Ridge, N; Lademacher, C; Macdonald, PA; Schumacher, HR; Streit, J; Wortmann, RL1
Yu, KH1
Kirkpatrick, P; Pascual, E; Sivera, F; Yasothan, U1
Becker, MA; Lademacher, C; Lloyd, E; MacDonald, PA; Schumacher, HR1
Keenan, RT; Pillinger, MH1
Lioté, F; Perez-Ruiz, F; Scavulli, J; Terkeltaub, R; Zelman, D1
Pandor, A; Stevenson, M2
Hall, HA; Poon, SH; Zimmermann, B1
Ernst, ME; Fravel, MA1
Sundy, JS1
Jansen, TL; Reinders, MK1
Becker, MA; Espinoza, LR; Lademacher, C; Lloyd, E; MacDonald, P; Schumacher, HR; Wells, AF1
Barrons, R; Love, BL; Snider, KM; Veverka, A1
Quillen, DM1
Graser, E; Pope, RS; Zychowicz, ME1
Gunawardhana, L; Hunt, B; Macdonald, PA; Whelton, A; Zhao, L1
Gray, CL; Walters-Smith, NE1
Hunt, B; Jackson, RL; Macdonald, PA; Wortmann, RL1
Dubost, JJ; Mathieu, S; Soubrier, M1
Doghramji, PP1
Hosoya, T; Kamatani, N; Naoyuki, K; Tatsuo, H1
Fujimori, S; Hada, T; Hosoya, T; Kamatani, N; Kohri, K; Matsuzawa, Y; Nakamura, T; Ueda, T; Yamamoto, T; Yamanaka, H2
Hosoya, T; Iwao, O; Ohno, I; Tatsuo, H1
Fujimori, S; Hada, T; Hisashi, Y; Hosoya, T; Kamatani, N; Kenjiro, K; Kohri, K; Matsuzawa, Y; Nakamura, T; Naoyuki, K; Shin, F; Takanori, U; Tatsuo, H; Tetsuya, Y; Toshikazu, H; Toshitaka, N; Ueda, T; Yamamoto, T; Yamanaka, H; Yuji, M2
Becker, MA; Chefo, S; Chohan, S; Jackson, RL; MacDonald, PA1
Schmidt, BM; Wagner, AD1
Becker, MA; Gunawardhana, L; Hunt, B; MacDonald, PA1
Hunt, B; Jackson, RL; MacDonald, PA1
Curiel, RV; Guzman, NJ1
Manger, B1
Isaka, Y; Kaimori, JY; Kawada, N; Kitamura, H; Moriyama, T; Rakugi, H; Takahara, S; Tsuda, H1
Butani, L; Calogiuri, G; Di Leo, E; Ferrannini, A; Foti, C; Nettis, E1
Keenan, RT1
Lopez-Olivo, MA; Suarez-Almazor, ME; Tayar, JH1
Akimoto, T; Horikoshi, R; Inoue, M; Kusano, E; Morishita, Y1
Chen, S; Cheng, Q; Li, Q; Liu, L; Luo, T; Lv, Q; Mei, M; Yang, S; Ye, P; Zhang, W1
Chefo, S; Gunawardhana, L; MacDonald, PA; Whelton, A1
Iwatani, M; Wasada, T1
Yamamoto, T1
Bomalaski, JS; Clark, MA1
Hoshide, S; Kamatani, N; Kobayashi, H; Komoriya, K; Kubo, J; Nakachi, T; Takeda, K; Tsuchimoto, M; Yamanaka, H1
Becker, MA; Eustace, D; Joseph-Ridge, N; MacDonald, PA; Palo, WA; Schumacher, HR; Vernillet, L; Wortmann, RL1
Schumacher, HR1
Becker, MA; Eustace, D; Joseph-Ridge, N; MacDonald, PA; Palo, WA; Schumacher, HR; Streit, J; Wortmann, RL1
Moreland, LW1
Lee, SJ; Terkeltaub, RA1
Murphy, G; Pohar, S1
Ziegler, R1
Bruce, SP1
Abeles, AM; Pillinger, MH; Rosenthal, P1
Avila-Casado, C; Franco, M; Johnson, RJ; Sánchez-Lozada, LG; Soto, V; Tapia, E; Zhao, L1
Okamoto, K1
Avila-Casado, C; Franco, M; Johnson, RJ; Sánchez-Lozada, LG; Soto, V; Tapia, E; Wessale, JL; Zhao, L1

Reviews

37 review(s) available for thiazoles and Hyperuricemia

ArticleYear
[The cutting-edge of medicine; role of hyperuricemia in cardiorenal syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2013, Jun-10, Volume: 102, Issue:6

    Topics: Cardio-Renal Syndrome; Febuxostat; Humans; Hypertension; Hyperuricemia; Renal Insufficiency, Chronic; Thiazoles; Treatment Outcome

2013
A systematic review and meta-analysis on the safety and efficacy of febuxostat versus allopurinol in chronic gout.
    Seminars in arthritis and rheumatism, 2013, Volume: 43, Issue:3

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Treatment Outcome; Uric Acid

2013
Tumor lysis syndrome: new challenges and recent advances.
    Advances in chronic kidney disease, 2014, Volume: 21, Issue:1

    Topics: Acute Kidney Injury; Allopurinol; Bicarbonates; Buffers; Calcium; Diuretics; Enzyme Inhibitors; Febuxostat; Fluid Therapy; Humans; Hyperkalemia; Hyperphosphatemia; Hyperuricemia; Hypocalcemia; Renal Dialysis; Thiazoles; Tumor Lysis Syndrome; Urate Oxidase

2014
Febuxostat: drug review and update.
    Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:5

    Topics: Animals; Arthritis, Gouty; Enzyme Inhibitors; Febuxostat; Gout Suppressants; Hepatic Insufficiency; Humans; Hyperuricemia; Liver; Thiazoles; Xanthine Oxidase

2014
Therapeutic approaches to chronic hyperuricemia and gout.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2014, Volume: 21, Issue:4

    Topics: Allopurinol; Cardiovascular Diseases; Chronic Disease; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Kidney Diseases; Life Style; Patient Education as Topic; Thiazoles; Xanthine Oxidase

2014
Long-term management of gout: nonpharmacologic and pharmacologic therapies.
    Rheumatic diseases clinics of North America, 2014, Volume: 40, Issue:2

    Topics: Allopurinol; Benzbromarone; Chronic Disease; Febuxostat; Feeding Behavior; Gout; Gout Suppressants; Humans; Hyperuricemia; Polyethylene Glycols; Risk Reduction Behavior; Thiazoles; Urate Oxidase; Uricosuric Agents

2014
Febuxostat.
    Drugs, 2008, Volume: 68, Issue:13

    Topics: Administration, Oral; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Molecular Structure; Randomized Controlled Trials as Topic; Thiazoles; Treatment Outcome; Uric Acid

2008
Febuxostat: a novel non-purine selective inhibitor of xanthine oxidase for the treatment of hyperuricemia in gout.
    Recent patents on inflammation & allergy drug discovery, 2007, Volume: 1, Issue:1

    Topics: Animals; Clinical Trials as Topic; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Patents as Topic; Thiazoles; Xanthine Oxidase

2007
Febuxostat: a new treatment for hyperuricaemia in gout.
    Rheumatology (Oxford, England), 2009, Volume: 48 Suppl 2

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Randomized Controlled Trials as Topic; Thiazoles

2009
Febuxostat: a new agent for lowering serum urate.
    Drugs of today (Barcelona, Spain : 1998), 2009, Volume: 45, Issue:4

    Topics: Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Interactions; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Kidney Diseases; Liver Diseases; Thiazoles

2009
Febuxostat for the treatment of hyperuricaemia in people with gout: a single technology appraisal.
    Health technology assessment (Winchester, England), 2009, Volume: 13 Suppl 3

    Topics: Allopurinol; Cost-Benefit Analysis; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Randomized Controlled Trials as Topic; Thiazoles

2009
Approach to the treatment of hyperuricemia.
    Medicine and health, Rhode Island, 2009, Volume: 92, Issue:11

    Topics: Allopurinol; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Uric Acid; Uricosuric Agents; Xanthine Oxidase

2009
Febuxostat: a selective xanthine-oxidase/xanthine-dehydrogenase inhibitor for the management of hyperuricemia in adults with gout.
    Clinical therapeutics, 2009, Volume: 31, Issue:11

    Topics: Allopurinol; Biotransformation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Febuxostat; Gout; Gout Suppressants; Half-Life; Humans; Hyperuricemia; Thiazoles; Tissue Distribution; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase

2009
Progress in the pharmacotherapy of gout.
    Current opinion in rheumatology, 2010, Volume: 22, Issue:2

    Topics: Allopurinol; Clinical Trials as Topic; Colchicine; Drug Therapy, Combination; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Recombinant Fusion Proteins; Thiazoles; Uricosuric Agents

2010
Management of hyperuricemia in gout: focus on febuxostat.
    Clinical interventions in aging, 2010, Feb-02, Volume: 5

    Topics: Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Treatment Outcome; Xanthine Oxidase

2010
New agents for the treatment of gout and hyperuricemia: febuxostat, puricase, and beyond.
    Current rheumatology reports, 2010, Volume: 12, Issue:2

    Topics: Acute Disease; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Polyethylene Glycols; Thiazoles; Urate Oxidase

2010
Urate-lowering therapy for gout: focus on febuxostat.
    Pharmacotherapy, 2010, Volume: 30, Issue:6

    Topics: Clinical Trials as Topic; Drug Interactions; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Models, Biological; Thiazoles; Xanthine Oxidase

2010
Crystal arthropathies: recognizing and treating "the gouch".
    Primary care, 2010, Volume: 37, Issue:4

    Topics: Allopurinol; Antimetabolites; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thiazoles; Uric Acid; Uricosuric Agents

2010
Febuxostat for the management of hyperuricaemia in patients with gout: a NICE single technology appraisal.
    PharmacoEconomics, 2011, Volume: 29, Issue:2

    Topics: Biomedical Technology; Clinical Trials as Topic; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles

2011
Febuxostat for treatment of chronic gout.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2011, Mar-01, Volume: 68, Issue:5

    Topics: Allopurinol; Animals; Chronic Disease; Clinical Trials as Topic; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Xanthine Oxidase

2011
[Treatment of gout].
    La Revue de medecine interne, 2011, Volume: 32, Issue:12

    Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Uric Acid; Uricosuric Agents

2011
Managing your patient with gout: a review of treatment options.
    Postgraduate medicine, 2011, Volume: 123, Issue:3

    Topics: Allopurinol; Anti-Inflammatory Agents; Colchicine; Diet; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Life Style; Patient Education as Topic; Quality of Life; Risk Factors; Thiazoles

2011
A new standard of care? Studies on febuxostat in the management of hyperuricemia with and without gout.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:4 Suppl 2

    Topics: Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Primary Health Care; Thiazoles; Treatment Outcome; Uric Acid; Xanthine Oxidase

2011
[Hyperuricemia, gout, pseudogout and concomitant diseases].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:48

    Topics: Allopurinol; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Chondrocalcinosis; Comorbidity; Diabetes Mellitus, Type 2; Febuxostat; Gout; Gout Suppressants; Guideline Adherence; Humans; Hypertrophy, Left Ventricular; Hyperuricemia; Interleukin 1 Receptor Antagonist Protein; Kidney Failure, Chronic; Thiazoles; Xanthine Oxidase

2011
Challenges associated with the management of gouty arthritis in patients with chronic kidney disease: a systematic review.
    Seminars in arthritis and rheumatism, 2012, Volume: 42, Issue:2

    Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Colchicine; Comorbidity; Contraindications; Febuxostat; Glucocorticoids; Gout Suppressants; Humans; Hyperuricemia; Polyethylene Glycols; Probenecid; PubMed; Renal Insufficiency, Chronic; Secondary Prevention; Thiazoles; Urate Oxidase

2012
[Gout and other crystal-induced arthritides].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:31-32

    Topics: Absorptiometry, Photon; Aged; Allopurinol; Arthritis, Gouty; Chondrocalcinosis; Cross-Sectional Studies; Enzymes, Immobilized; Evidence-Based Medicine; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Male; Middle Aged; Odds Ratio; Polyethylene Glycols; Risk Factors; Thiazoles; Ultrasonography; Urate Oxidase

2012
Safety of urate-lowering therapies: managing the risks to gain the benefits.
    Rheumatic diseases clinics of North America, 2012, Volume: 38, Issue:4

    Topics: Allopurinol; Comorbidity; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Risk Factors; Thiazoles; Uric Acid

2012
Febuxostat for treating chronic gout.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Allopurinol; Chronic Disease; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Randomized Controlled Trials as Topic; Thiazoles

2012
Efficacy and tolerability of febuxostat in hyperuricemic patients with or without gout: a systematic review and meta-analysis.
    Clinical therapeutics, 2013, Volume: 35, Issue:2

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid

2013
[Uric acid metabolism and insulin resistance in type 2 diabetes].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 8

    Topics: Cardiovascular Diseases; Chromans; Diabetes Mellitus, Type 2; Humans; Hyperuricemia; Insulin Resistance; Thiazoles; Thiazolidinediones; Troglitazone; Uric Acid

2002
[Development antihyperuricemic candidates].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1

    Topics: Animals; Drug Design; Enzyme Inhibitors; Febuxostat; Humans; Hyperuricemia; Pyrazoles; Tetrazoles; Thiazoles; Urate Oxidase; Uricosuric Agents; Xanthine Oxidase

2003
Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase.
    Current rheumatology reports, 2004, Volume: 6, Issue:3

    Topics: Allopurinol; Amlodipine; Clinical Trials as Topic; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hyperuricemia; Losartan; Pyrazoles; Thiazoles; Treatment Outcome; Urate Oxidase; Uric Acid; Xanthine Oxidase

2004
Febuxostat: a non-purine, selective inhibitor of xanthine oxidase for the management of hyperuricaemia in patients with gout.
    Expert opinion on investigational drugs, 2005, Volume: 14, Issue:7

    Topics: Disease Management; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hyperuricemia; Thiazoles; Xanthine Oxidase

2005
New developments in clinically relevant mechanisms and treatment of hyperuricemia.
    Current rheumatology reports, 2006, Volume: 8, Issue:3

    Topics: Febuxostat; Humans; Hyperuricemia; Prognosis; Thiazoles; Urate Oxidase; Uric Acid; Uricosuric Agents; Xanthine Oxidase

2006
Febuxostat: a selective xanthine oxidase inhibitor for the treatment of hyperuricemia and gout.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:12

    Topics: Febuxostat; Gout; Humans; Hyperuricemia; Thiazoles; Xanthine Oxidase

2006
Hyperuricemia and gout: new insights into pathogenesis and treatment.
    Bulletin of the NYU hospital for joint diseases, 2007, Volume: 65, Issue:3

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Interleukin 1 Receptor Antagonist Protein; Thiazoles; Urate Oxidase; Uric Acid

2007
[Inhibitors of xanthine oxidoreductase].
    Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:4

    Topics: Allopurinol; Drug Design; Enzyme Inhibitors; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Nitriles; Pyrazoles; Pyridines; Thiazoles; Xanthine Dehydrogenase

2008

Trials

23 trial(s) available for thiazoles and Hyperuricemia

ArticleYear
Evaluation of the Relationship Between Serum Urate Levels, Clinical Manifestations of Gout, and Death From Cardiovascular Causes in Patients Receiving Febuxostat or Allopurinol in an Outcomes Trial.
    Arthritis & rheumatology (Hoboken, N.J.), 2022, Volume: 74, Issue:9

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Treatment Outcome; Uric Acid

2022
Comparison of febuxostat and allopurinol for hyperuricemia in cardiac surgery patients (NU-FLASH Trial).
    Circulation journal : official journal of the Japanese Circulation Society, 2013, Volume: 77, Issue:8

    Topics: Aged; Albuminuria; Allopurinol; Arachidonic Acid; Blood Pressure; C-Reactive Protein; Cardiac Surgical Procedures; Cholesterol; Creatinine; Cystatin C; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Lipoproteins, LDL; Male; Middle Aged; Pulse Wave Analysis; Stroke Volume; Thiazoles; Uric Acid

2013
Febuxostat (Feburic tablet) in the management of hyperuricemia in a general practice cohort of Japanese patients with a high prevalence of cardiovascular problems.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:6

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Comorbidity; Dose-Response Relationship, Drug; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Longitudinal Studies; Male; Middle Aged; Prevalence; Thiazoles; Treatment Outcome; Uric Acid

2014
The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: study protocol for a multicenter randomized controlled study.
    Trials, 2014, Jan-16, Volume: 15

    Topics: Administration, Oral; Biomarkers; Clinical Protocols; Double-Blind Method; Drug Administration Schedule; Febuxostat; Glomerular Filtration Rate; Gout Suppressants; Humans; Hyperuricemia; Japan; Kidney; Prospective Studies; Renal Insufficiency, Chronic; Research Design; Risk Factors; Severity of Illness Index; Tablets; Thiazoles; Time Factors; Treatment Outcome; Up-Regulation; Uric Acid

2014
An allopurinol-controlled, multicenter, randomized, double-blind, parallel between-group, comparative study of febuxostat in Chinese patients with gout and hyperuricemia.
    International journal of rheumatic diseases, 2014, Volume: 17, Issue:6

    Topics: Adult; Allopurinol; Biomarkers; China; Double-Blind Method; Enzyme Inhibitors; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Remission Induction; Thiazoles; Time Factors; Treatment Outcome; Uric Acid; Xanthine Oxidase

2014
Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:12

    Topics: Adult; Aged; Colchicine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Thioglycolates; Triazoles; Uric Acid

2014
Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy: a phase III, randomized, multi-center trial comparing febuxostat and allopurinol.
    International journal of clinical oncology, 2016, Volume: 21, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Neoplasms; Thiazoles; Tumor Lysis Syndrome; Uric Acid; Xanthine Oxidase; Young Adult

2016
Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial.
    Arthritis and rheumatism, 2008, Nov-15, Volume: 59, Issue:11

    Topics: Adult; Aged; Allopurinol; Creatinine; Dose-Response Relationship, Drug; Double-Blind Method; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Treatment Outcome; Uric Acid

2008
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
    Arthritis research & therapy, 2010, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Comorbidity; Dose-Response Relationship, Drug; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperlipidemias; Hypertension; Hyperuricemia; Kidney Diseases; Male; Middle Aged; Obesity; Thiazoles; Treatment Outcome; United States; Uric Acid; Young Adult

2010
Renal function in gout: long-term treatment effects of febuxostat.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:1

    Topics: Adult; Aged; Double-Blind Method; Febuxostat; Female; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Thiazoles; Young Adult

2011
Effect of prophylaxis on gout flares after the initiation of urate-lowering therapy: analysis of data from three phase III trials.
    Clinical therapeutics, 2010, Volume: 32, Issue:14

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Double-Blind Method; Drug Administration Schedule; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Treatment Outcome; Uric Acid; Young Adult

2010
An allopurinol-controlled, randomized, double-dummy, double-blind, parallel between-group, comparative study of febuxostat (TMX-67), a non-purine-selective inhibitor of xanthine oxidase, in patients with hyperuricemia including those with gout in Japan: p
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:4 Suppl 2

    Topics: Administration, Oral; Allopurinol; Dose-Response Relationship, Drug; Double-Blind Method; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Japan; Male; Middle Aged; Thiazoles; Treatment Outcome; Uric Acid; Xanthine Oxidase

2011
A repeated oral administration study of febuxostat (TMX-67), a non-purine-selective inhibitor of xanthine oxidase, in patients with impaired renal function in Japan: pharmacokinetic and pharmacodynamic study.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:4 Suppl 2

    Topics: Administration, Oral; Adult; Aged; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Febuxostat; Female; Follow-Up Studies; Glomerular Filtration Rate; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Oxypurinol; Renal Insufficiency; Thiazoles; Treatment Outcome; Uric Acid; Xanthine Oxidase; Young Adult

2011
Placebo-controlled double-blind dose-response study of the non-purine-selective xanthine oxidase inhibitor febuxostat (TMX-67) in patients with hyperuricemia (including gout patients) in japan: late phase 2 clinical study.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:4 Suppl 2

    Topics: Administration, Oral; Dose-Response Relationship, Drug; Double-Blind Method; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Japan; Male; Middle Aged; Thiazoles; Treatment Outcome; Uric Acid; Xanthine Oxidase

2011
An allopurinol-controlled, multicenter, randomized, open-label, parallel between-group, comparative study of febuxostat (TMX-67), a non-purine-selective inhibitor of xanthine oxidase, in patients with hyperuricemia including those with gout in Japan: phas
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:4 Suppl 2

    Topics: Administration, Oral; Allopurinol; Dose-Response Relationship, Drug; Double-Blind Method; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Japan; Male; Middle Aged; Thiazoles; Time Factors; Treatment Outcome; Uric Acid; Xanthine Oxidase

2011
Multicenter, open-label study of long-term administration of febuxostat (TMX-67) in Japanese patients with hyperuricemia including gout.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:4 Suppl 2

    Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Japan; Male; Middle Aged; Thiazoles; Time Factors; Treatment Outcome; Uric Acid; Xanthine Oxidase

2011
Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol.
    Arthritis care & research, 2012, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Cardiovascular Diseases; Comorbidity; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Illinois; Male; Metabolic Diseases; Middle Aged; Obesity; Retrospective Studies; Sex Factors; Thiazoles; Treatment Outcome; Uric Acid; Young Adult

2012
Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects.
    Nucleosides, nucleotides & nucleic acids, 2011, Volume: 30, Issue:12

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Liver Function Tests; Male; Middle Aged; Thiazoles; Treatment Outcome; Uric Acid

2011
The efficacy and safety of febuxostat for urate lowering in gout patients ≥65 years of age.
    BMC geriatrics, 2012, Mar-21, Volume: 12

    Topics: Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Double-Blind Method; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Thiazoles; Treatment Outcome; Uric Acid; Xanthine Oxidase

2012
Preservation of renal function during gout treatment with febuxostat: a quantitative study.
    Postgraduate medicine, 2013, Volume: 125, Issue:1

    Topics: Adult; Aged; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Kidney; Kidney Function Tests; Male; Middle Aged; Thiazoles; Treatment Outcome; Uric Acid

2013
Pharmacokinetics and pharmacodynamics of febuxostat (TMX-67), a non-purine selective inhibitor of xanthine oxidase/xanthine dehydrogenase (NPSIXO) in patients with gout and/or hyperuricemia.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Area Under Curve; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hyperuricemia; Male; Oxygen; Thiazoles; Time Factors; Xanthine Dehydrogenase; Xanthine Oxidase

2004
Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Febuxostat; Female; Gout; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Treatment Outcome; Uric Acid; Xanthine Oxidase

2005
Febuxostat compared with allopurinol in patients with hyperuricemia and gout.
    The New England journal of medicine, 2005, Dec-08, Volume: 353, Issue:23

    Topics: Allopurinol; Double-Blind Method; Enzyme Inhibitors; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Uric Acid; Xanthine Oxidase

2005

Other Studies

40 other study(ies) available for thiazoles and Hyperuricemia

ArticleYear
Identification of 5-[5-cyano-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamido] thiazole-4-carboxylic acid as a promising dual inhibitor of urate transporter 1 and xanthine oxidase.
    European journal of medicinal chemistry, 2023, Sep-05, Volume: 257

    Topics: Animals; Carboxylic Acids; HEK293 Cells; Humans; Hyperuricemia; Indoles; Rats; Thiazoles; Xanthine Oxidase

2023
Efficacy of febuxostat versus allopurinol and the predictors of achieving target serum urate in a cohort of Thai people with gout.
    Clinical rheumatology, 2021, Volume: 40, Issue:1

    Topics: Allopurinol; Cohort Studies; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Retrospective Studies; Thailand; Thiazoles; Treatment Outcome; Uric Acid

2021
[Case presentation--tophaceous gout].
    MMW Fortschritte der Medizin, 2012, Apr-05, Volume: 154 Suppl 1

    Topics: Aged, 80 and over; Arthritis, Gouty; Drug Therapy, Combination; Febuxostat; Female; Follow-Up Studies; Gout Suppressants; Hand Deformities, Acquired; Humans; Hyperuricemia; Mobility Limitation; Thiazoles; Uric Acid

2012
Acute neutropenia associated with initiation of febuxostat therapy for hyperuricaemia in patients with chronic kidney disease.
    Journal of clinical pharmacy and therapeutics, 2013, Volume: 38, Issue:3

    Topics: Aged; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Male; Neutropenia; Renal Insufficiency, Chronic; Thiazoles

2013
Cost-effectiveness of febuxostat in chronic gout.
    The European journal of health economics : HEPAC : health economics in prevention and care, 2014, Volume: 15, Issue:5

    Topics: Cost-Benefit Analysis; Dose-Response Relationship, Drug; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Markov Chains; Models, Economic; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Reproducibility of Results; Thiazoles; Uric Acid

2014
Febuxostat for treating allopurinol-resistant hyperuricemia in patients with chronic kidney disease.
    Renal failure, 2014, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Creatinine; Enzyme Inhibitors; Febuxostat; Glomerular Filtration Rate; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Renal Insufficiency, Chronic; Retrospective Studies; Thiazoles; Uric Acid

2014
CaseBook challenges: Managing gout, hyperuricemia and comorbidities -- dialogue with the experts.
    The American journal of medicine, 2014, Volume: 127, Issue:1

    Topics: Allopurinol; Comorbidity; Disease Management; Drug Administration Schedule; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Medication Adherence; Primary Health Care; Risk Factors; Severity of Illness Index; Thiazoles; United States; Uric Acid

2014
Efficacy and safety of febuxostat in the treatment of hyperuricemia in stable kidney transplant recipients.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Adult; Aged; Febuxostat; Female; Glomerular Filtration Rate; Gout Suppressants; Humans; Hyperuricemia; Kidney Transplantation; Male; Middle Aged; Practice Patterns, Physicians'; Retrospective Studies; Thiazoles; Uric Acid; Xanthine Oxidase

2014
Rhabdomyolysis associated with initiation of febuxostat therapy for hyperuricaemia in a patient with chronic kidney disease.
    Journal of clinical pharmacy and therapeutics, 2014, Volume: 39, Issue:3

    Topics: Aged; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Renal Insufficiency, Chronic; Rhabdomyolysis; Thiazoles

2014
Successful treatment of refractory gout using combined therapy consisting of febuxostat and allopurinol in a patient with chronic renal failure.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:6

    Topics: Adrenal Cortex Hormones; Aged; Allopurinol; Arthritis, Gouty; Benzbromarone; Drug Therapy, Combination; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Kidney Failure, Chronic; Male; Thiazoles; Treatment Outcome; Xanthine Oxidase

2014
Efficacy and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase for the treatment of hyperuricemia in kidney transplant recipients.
    Transplantation proceedings, 2014, Volume: 46, Issue:2

    Topics: Aged; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Kidney Transplantation; Male; Middle Aged; Thiazoles; Xanthine Oxidase

2014
Prevalence of treatment of hyperuricemic in patients admitted to the rheumatology ward and evaluation of compliance with the 2012 ACR Guidelines.
    Joint bone spine, 2014, Volume: 81, Issue:5

    Topics: Aged; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Guideline Adherence; Hospitalization; Humans; Hyperuricemia; Male; Prevalence; Thiazoles; Xanthine Oxidase

2014
Treat to target in gout by combining two modes of action.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:12

    Topics: Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Thiazoles; Thioglycolates; Triazoles

2014
A new xanthine oxidase inhibitor: the uric acid reduction and additional efficacy in CKD patients.
    Clinical and experimental nephrology, 2014, Volume: 18, Issue:6

    Topics: Enzyme Inhibitors; Febuxostat; Humans; Hyperuricemia; Nitriles; Pyridines; Renal Insufficiency, Chronic; Thiazoles; Treatment Outcome; Uric Acid; Xanthine Oxidase

2014
Switching from allopurinol to febuxostat for the treatment of hyperuricemia and renal function in patients with chronic kidney disease.
    Clinical rheumatology, 2014, Volume: 33, Issue:11

    Topics: Aged; Aged, 80 and over; Allopurinol; Disease Progression; Drug Substitution; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Renal Insufficiency, Chronic; Retrospective Studies; Thiazoles; Treatment Outcome; Uric Acid

2014
Efficacy and safety of febuxostat in elderly female patients.
    Clinical interventions in aging, 2014, Volume: 9

    Topics: Aged; Comorbidity; Febuxostat; Female; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Retrospective Studies; Thiazoles; Treatment Outcome

2014
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:12

    Topics: Aged; Aged, 80 and over; Allopurinol; Cross-Sectional Studies; Febuxostat; Female; Gout Suppressants; Hospitals; Humans; Hyperuricemia; Inappropriate Prescribing; Italy; Male; Patient Admission; Patient Discharge; Registries; Risk; Thiazoles; Xanthine Oxidase

2014
Suggested statistical reappraisal of data from comparative study of febuxostat and allopurinol in chronic kidney disease.
    Clinical rheumatology, 2014, Volume: 33, Issue:12

    Topics: Allopurinol; Female; Gout Suppressants; Humans; Hyperuricemia; Kidney; Male; Renal Insufficiency, Chronic; Thiazoles

2014
The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Jul-01, Volume: 309, Issue:1

    Topics: Animals; Apoptosis; Choline Deficiency; Cytoprotection; Diet, High-Fat; Enzyme Inhibitors; Febuxostat; Gout Suppressants; Hyperuricemia; Liver; Liver Cirrhosis, Experimental; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Thiazoles; Uric Acid; Xanthine Oxidase

2015
Structure-based design and biological evaluation of novel 2-(indol-2-yl) thiazole derivatives as xanthine oxidase inhibitors.
    Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3

    Topics: Administration, Oral; Animals; Binding Sites; Cattle; Drug Design; Enzyme Inhibitors; Half-Life; Hyperuricemia; Microsomes, Liver; Molecular Docking Simulation; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles; Uric Acid; Xanthine Oxidase

2016
Febuxostat for Asymptomatic Hyperuricemia in CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016, Volume: 67, Issue:6

    Topics: Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Renal Insufficiency, Chronic; Thiazoles; Uric Acid; Xanthine Oxidase

2016
Febuxostat Renoprotection in CKD Patients With Asymptomatic Hyperuricemia.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016, Volume: 67, Issue:6

    Topics: Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Renal Insufficiency, Chronic; Thiazoles; Uric Acid

2016
In Reply to 'Febuxostat for Asymptomatic Hyperuricemia in CKD' and 'Febuxostat Renoprotection in CKD Patients With Asymptomatic Hyperuricemia'.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016, Volume: 67, Issue:6

    Topics: Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Renal Insufficiency, Chronic; Thiazoles; Uric Acid

2016
Febuxostat for Patients With Gout and Severe Chronic Kidney Disease: Which Is the Appropriate Dosage? Comment on the Article by Saag et al.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:10

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Renal Insufficiency, Chronic; Thiazoles; Uric Acid

2016
Febuxostat: a viewpoint by H. Ralph Schumacher Jr and Lan X. Chen.
    Drugs, 2008, Volume: 68, Issue:13

    Topics: Administration, Oral; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Uric Acid

2008
Febuxostat : a viewpoint by Naomi Schlesinger.
    Drugs, 2008, Volume: 68, Issue:13

    Topics: Administration, Oral; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Uric Acid

2008
Febuxostat : a viewpoint by N. Lawrence Edwards.
    Drugs, 2008, Volume: 68, Issue:13

    Topics: Administration, Oral; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Uric Acid

2008
Febuxostat.
    Nature reviews. Drug discovery, 2009, Volume: 8, Issue:3

    Topics: Chronic Disease; Drug Approval; European Union; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Xanthine Oxidase

2009
Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout.
    The Journal of rheumatology, 2009, Volume: 36, Issue:6

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Hyperuricemia; Thiazoles; Treatment Outcome; Uric Acid

2009
Gout Study Group: update on hyperuricemia and gout.
    Joint bone spine, 2009, Volume: 76, Issue:4

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diet; Europe; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Life Style; Prednisone; Prevalence; Thiazoles; United States; Uric Acid

2009
Febuxostat: new drug. Hyperuricaemia: risk of gout attacks.
    Prescrire international, 2009, Volume: 18, Issue:100

    Topics: Allopurinol; Drug Approval; Europe; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Randomized Controlled Trials as Topic; Thiazoles

2009
The current state of care in gout: Addressing the need for better understanding of an ancient disease.
    Journal of the American Academy of Nurse Practitioners, 2010, Volume: 22 Suppl 1

    Topics: Acute Disease; Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthritis, Rheumatoid; Chronic Disease; Colchicine; Comorbidity; Disease Progression; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Patient Education as Topic; Quality of Life; Risk Factors; Thiazoles; Uric Acid; Uricosuric Agents; Xanthine Oxidase

2010
Febuxostat suppressed renal ischemia-reperfusion injury via reduced oxidative stress.
    Biochemical and biophysical research communications, 2012, Oct-19, Volume: 427, Issue:2

    Topics: Animals; Apoptosis; Endoplasmic Reticulum Stress; Febuxostat; Hyperuricemia; Kidney; Kidney Tubules; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiazoles; Xanthine Dehydrogenase; Xanthine Oxidase

2012
Allopurinol hypersensitivity reactions: desensitization strategies and new therapeutic alternative molecules.
    Inflammation & allergy drug targets, 2013, Volume: 12, Issue:1

    Topics: Allopurinol; Animals; Desensitization, Immunologic; Drug Hypersensitivity; Febuxostat; Gout; Humans; Hyperuricemia; Product Surveillance, Postmarketing; Recombinant Proteins; Skin; Thiazoles; Urate Oxidase

2013
Febuxostat for hyperuricemia: experience with patients on chronic hemodialysis treatment.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Biomarkers; Drug Monitoring; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Renal Dialysis; Thiazoles; Time Factors; Treatment Outcome; Uric Acid

2013
Febuxostat--treatment for hyperuricemia and gout?
    The New England journal of medicine, 2005, Dec-08, Volume: 353, Issue:23

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thiazoles; Uric Acid; Xanthine Oxidase

2005
Febuxostat for prevention of gout attacks.
    Issues in emerging health technologies, 2006, Issue:87

    Topics: Allopurinol; Canada; Clinical Trials, Phase III as Topic; Gout; Gout Suppressants; Humans; Hyperuricemia; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid; Xanthine Oxidase

2006
[Febuxostat versus allopurinol for hyperuricemia].
    Medizinische Monatsschrift fur Pharmazeuten, 2006, Volume: 29, Issue:10

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles

2006
Treatment with the xanthine oxidase inhibitor febuxostat lowers uric acid and alleviates systemic and glomerular hypertension in experimental hyperuricaemia.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:4

    Topics: Animals; Blood Pressure; Febuxostat; Follow-Up Studies; Gout Suppressants; Hypertension, Renal; Hyperuricemia; Kidney Glomerulus; Male; Oxonic Acid; Rats; Rats, Sprague-Dawley; Renal Circulation; Thiazoles; Uric Acid; Xanthine Oxidase

2008
Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia.
    Nephron. Physiology, 2008, Volume: 108, Issue:4

    Topics: Animals; Disease Models, Animal; Febuxostat; Hyperuricemia; Kidney; Kidney Failure, Chronic; Male; Microcirculation; Nephrectomy; Oxonic Acid; Rats; Rats, Wistar; Recovery of Function; Thiazoles; Treatment Outcome

2008