Page last updated: 2024-08-21

thiazoles and Hyperinsulinism

thiazoles has been researched along with Hyperinsulinism in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	28 (46.67)	18.2507
2000's	32 (53.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kono, S	1
Kotake, H	1
Cooney, GJ; Dzamko, N; Ellis, B; Frangioudakis, G; Furler, SM; Iglesias, MA; Kraegen, EW; Ye, JM	1
Banday, AA; Hussain, T; Lokhandwala, MF; Umrani, DN	1
Cleasby, ME; Livingstone, DE; Nyirenda, MJ; Seckl, JR; Walker, BR	1
Hoogwerf, BJ; Nambi, V; Sprecher, DL	1
Fujioka, Y; Iwasaki, T; Masai, M; Morimoto, S; Ohyanagi, M; Okumura, T; Tsuboi, S; Tsujino, T	1
Inoue, T; Kashiwabara, A; Kawasaki, T; Ogata, N; Sawashige, K; Sekino, N; Yamanouchi, T	1
Azziz, R; Ehrmann, DA; Fereshetian, AG; Ghazzi, MN; Legro, RS; O'Keefe, M	1
Odaka, H; Suzuki, M	1
Abrahmsen, LB; Alberts, P; Ashkzari, M; Bergqvist, E; Björkstrand, E; Edling, NH; Engblom, LO; Fiedler, M; Forsgren, M; Klingström, G; Larsson, C; Nilsson, C; Nilsson, CE; Norling, S; Ohman, B; Selen, G	1
Barringhaus, KG; Chen, M; Czarnik, AC; Hesselbacher, S; Ley, K; Nadler, J; Phillips, JW; Sanders, JM; Sarembock, IJ; Yang, Z	1
Gao, KM; Khoursheed, M; Lee, MK; Miles, PD; Moossa, AR; Olefsky, JM	1
Reusch, JE	1
Beerdsen, P; Joyce, M; Ludvik, B; Nolan, JJ; Olefsky, J	1
Haber, RS; Holand, A; O'Boyle, E; Weinstein, SP	1
Higa, S; Ishikawa, K; Mimura, G; Murakami, K; Takasu, N; Yagi, N	1
Colca, JR; Corkey, BE; Cunningham, BA; Holbert, RI; Kurowski, TG; Ruderman, NB; Saha, AK	1
Kuehnle, HF	1
Caro, JF; Considine, RV; Nolan, JJ; Nyce, MR; Olefsky, JM	1
Henry, RR	1
Connell, J; Petrie, J; Small, M	1
Nestler, JE	1
Dunaif, A; Flier, JS; Mantzoros, CS	1
Hamada, Y; Ikegami, H; Ogihara, T	1
Cohen, A; Higo, K; Miles, PD; Olefsky, JM; Rafaat, K; Romeo, OM	1
Arikawa, E; Bhanot, S; McNeill, JH; Verma, S; Yao, L	1
Akanuma, Y; Fujiwara, T; Horikoshi, H; Iwamoto, K; Kadowaki, T; Mori, Y; Okuno, A; Tamemoto, H; Tobe, K; Ueki, K; Umesono, K; Yazaki, Y	1
Hompes, PG; Lambalk, CB; van Hooff, MH; van Montfrans, JM	1
Kobayashi, M; Mitsuo, M; Nakai, I; Oka, T; Shimizu, Y; Takata, Y; Uchiyama, K	1
Lutterman, JA; Ong, MK; Smits, P; Tack, CJ	1
Greer, IA; Hopkinson, ZE; Sattar, N	1
Ehrmann, DA	1
Matsui, K; Nagao, K; Shibata, T; Shinkai, H; Wakitani, K; Yonemori, F	1
Horikoshi, H; Ito, T; Shiomi, M; Tsujita, Y; Tsukada, T	1
Mitsuo, M; Mizuta, N; Nakai, I; Nakajima, H; Oka, T; Okamoto, M; Omori, Y; Uchiyama, K; Yoshimura, N	1
Collier, G; Zimmet, P	1
Abe, H; Kusano, S	1
Shimamoto, K	1
Kuzuya, H; Nakano, T; Yamada, K	1
Gonzalez, R; Grinsell, JW; Lardinois, CK; Michaels, JR; Sare, JS; Starich, GH; Swislocki, A	1
Kadowaki, T	1
Kruszynska, YT; Olefsky, JM; Sobel, BE; Yu, JG	1
Higa, M; Kakuma, T; Lee, Y; Pan, W; Shimomura, I; Unger, RH; Wang, Zw	1
Taylor, AE	1
Johnson, JH; McCarthy, KJ; Routh, RE; Shaw, W; Walsh, K; Welbourne, TC	1
Daubresse, JC	1
Boehm, M; Crombie, DL; Davies, PJ; Depre, C; Heyman, RA; Leibowitz, MD; Liu, S; Nagy, L; Singh Ahuja, H; Tontonoz, P	1
Akiyama, T; Fukumitsu, KI; Jia, DM; Otsuki, M; Tabaru, A	1
Bodkin, NL; Hansen, BC; Kliewer, SA; Lambert, MH; Lewis, MC; Oliver, WR; Plunket, KD; Russell, CS; Shenk, JL; Snaith, MR; Sternbach, DD; Sznaidman, ML; Willson, TM; Winegar, DA; Xu, HE	1
Jacinto, SM; Ljung, B; Oakes, ND; Thalén, PG	1
Harano, Y	1
Cooney, GJ; Kraegen, EW; Thompson, AL; Ye, J	1
Chvojková, S; Divisová, J; Kazdová, L	1
Calvo Romero, JM; Lima Rodríguez, EM	1
Befroy, D; Cline, GW; Dufour, S; Enocksson, S; Hundal, RS; Inzucchi, SE; Lebon, V; Mayerson, AB; Petersen, KF; Shulman, GI	1
Brownsey, R; Demuth, HU; Finegood, DT; McIntosh, CH; Parkhouse, W; Pederson, RA; Pospisilik, JA; Stafford, SG	1
Fujiwara, T; Fukami, M; Fukuda, K; Horikoshi, H; Wada, M; Yoshioka, S; Yoshioka, T	1
Fujita, T; Ikeda, H; Shimura, Y; Sugiyama, Y; Taketomi, S	1
Clark, DA; Danbury, BH; Eggler, JF; Hall, KL; Holland, GF; Hutson, NJ; Krupp, MN; McPherson, RK; Stevenson, RW; Volkmann, RA	1

Reviews

19 review(s) available for thiazoles and Hyperinsulinism

Article	Year
[Insulin resistance in myotonic dystrophy]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 7 Topics: Chromans; Humans; Hyperinsulinism; Insulin Resistance; Insulin-Like Growth Factor I; Myotonic Dystrophy; Myotonin-Protein Kinase; Protein Kinases; Protein Serine-Threonine Kinases; Thiazoles; Thiazolidinediones; Trinucleotide Repeats; Troglitazone	2002
[Syndrome X]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 10 Topics: Animals; Bezafibrate; Biguanides; Fatty Acids, Nonesterified; Humans; Hyperglycemia; Hyperinsulinism; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Leptin; Life Style; Metabolic Syndrome; Pioglitazone; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha	2002
A truly deadly quartet: obesity, hypertension, hypertriglyceridemia, and hyperinsulinemia. Cleveland Clinic journal of medicine, 2002, Volume: 69, Issue:12 Topics: Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypoglycemic Agents; Hypolipidemic Agents; Male; Metabolic Syndrome; Metformin; Motor Activity; Obesity; Simvastatin; Thiazoles; Thiazolidinediones; Weight Loss	2002
[Hypertension and insulin resistance in obese type 2 diabetic Wistar fatty rat]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61, Issue:7 Topics: Animals; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin Resistance; Obesity; Pioglitazone; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones	2003
New therapeutic agents for the treatment of NIDDM. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1996, Volume: 104, Issue:2 Topics: Animals; Carbonates; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Molecular Structure; Prevalence; Thiazoles	1996
Effects of troglitazone on insulin sensitivity. Diabetic medicine : a journal of the British Diabetic Association, 1996, Volume: 13, Issue:9 Suppl 6 Topics: Animals; Blood Glucose; Blood Pressure; Chromans; Diabetes Mellitus, Type 2; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Obesity; Thiazoles; Thiazolidinediones; Troglitazone	1996
Role of hyperinsulinemia in the pathogenesis of the polycystic ovary syndrome, and its clinical implications. Seminars in reproductive endocrinology, 1997, Volume: 15, Issue:2 Topics: Adrenal Glands; Androgens; Anovulation; Chromans; Diazoxide; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Ovary; Polycystic Ovary Syndrome; Steroid 17-alpha-Hydroxylase; Thiazoles; Thiazolidinediones; Troglitazone	1997
[Insulin, as a regulating factor of blood pressure]. Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55, Issue:8 Topics: Animals; Cell Division; Chromans; Humans; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Kidney; Muscle, Smooth, Vascular; Sodium; Sympathetic Nervous System; Thiazoles; Thiazolidinediones; Troglitazone	1997
Treatment of hyperinsulinaemia in polycystic ovary syndrome? Human reproduction (Oxford, England), 1998, Volume: 13, Issue:1 Topics: Chromans; Diazoxide; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Thiazoles; Thiazolidinediones; Troglitazone	1998
Attenuation of hyperinsulinemia in polycystic ovary syndrome: what are the options? Journal of endocrinological investigation, 1998, Volume: 21, Issue:9 Topics: Chromans; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Thiazoles; Thiazolidinediones; Troglitazone	1998
Clinical efficacy of metformin against insulin resistance parameters: sinking the iceberg. Drugs, 1999, Volume: 58 Suppl 1 Topics: Animals; Blood Glucose; Cardiovascular Diseases; Chromans; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Metformin; Rats; Risk Factors; Thiazoles; Thiazolidinediones; Troglitazone	1999
[Insulin sensitizer and hypertension]. Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58, Issue:2 Topics: Animals; Cholesterol, HDL; Cholesterol, LDL; Chromans; Humans; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin Resistance; Rats; Syndrome; Thiazoles; Thiazolidinediones; Troglitazone	2000
[Cardiovascular effects of the thiazolidinedione troglitazone]. Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58, Issue:2 Topics: Animals; Arteriosclerosis; Cardiovascular Diseases; Cardiovascular System; Chromans; Diabetes Mellitus, Type 2; Humans; Hyperinsulinism; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Insulin Resistance; Risk Factors; Syndrome; Thiazoles; Thiazolidinediones; Troglitazone	2000
[Hypoglycemic agents to improve insulin resistance]. Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58, Issue:2 Topics: Adipocytes; Animals; Cell Differentiation; Chromans; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Hyperglycemia; Hyperinsulinism; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Obesity; Pioglitazone; Thiazoles; Thiazolidinediones; Troglitazone	2000
Insulin-lowering medications in polycystic ovary syndrome. Obstetrics and gynecology clinics of North America, 2000, Volume: 27, Issue:3 Topics: Diazoxide; Female; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Menstruation Disturbances; Metformin; Polycystic Ovary Syndrome; Thiazoles; Thiazolidinediones	2000
[The importance of syndrome X in daily practice]. Revue medicale de Bruxelles, 2000, Volume: 21, Issue:6 Topics: Anthropometry; Cardiovascular Diseases; Diet, Reducing; Exercise; Humans; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Lipoproteins, HDL; Lipoproteins, LDL; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones	2000
[Lipodystrophia]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 3 Topics: Animals; Cardiomyopathy, Hypertrophic; Chromans; Diabetes Mellitus; Diagnosis, Differential; Fatty Liver; Humans; Hyperinsulinism; Hypertriglyceridemia; Insulin Resistance; Insulin-Like Growth Factor I; Lipid Metabolism; Lipodystrophy; Prognosis; Thiazoles; Thiazolidinediones; Troglitazone	2001
Triglycerides, fatty acids and insulin resistance--hyperinsulinemia. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2001, Volume: 109, Issue:4 Topics: Adipose Tissue; Animals; Fatty Acids; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Lipolysis; Muscle, Skeletal; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transcription Factors; Triglycerides	2001
[Objectives and therapeutic strategy in type 2 diabetes mellitus]. Anales de medicina interna (Madrid, Spain : 1984), 2001, Volume: 18, Issue:7 Topics: Carbamates; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Piperidines; Thiazoles	2001

Trials

6 trial(s) available for thiazoles and Hyperinsulinism

Article	Year
Usefulness of troglitazone administration to obese hyperglycaemic patients with near-normoglycaemia. Diabetes, obesity & metabolism, 2003, Volume: 5, Issue:3 Topics: Adult; Aged; Blood Glucose; Chromans; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Obesity; Thiazoles; Thiazolidinediones; Troglitazone	2003
Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome. Fertility and sterility, 2003, Volume: 79, Issue:4 Topics: Adrenal Glands; Adult; Blood Glucose; Chromans; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glucose Tolerance Test; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Polycystic Ovary Syndrome; Prospective Studies; Thiazoles; Thiazolidinediones; Troglitazone	2003
Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. The New England journal of medicine, 1994, Nov-03, Volume: 331, Issue:18 Topics: Adult; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Lipids; Male; Obesity; Thiazoles; Thiazolidinediones; Troglitazone	1994
Leptin concentrations in the polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:6 Topics: Adult; Body Mass Index; Chromans; Double-Blind Method; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Obesity; Osmolar Concentration; Polycystic Ovary Syndrome; Proteins; Thiazoles; Thiazolidinediones; Troglitazone	1997
Treatment of hyperinsulinaemia in polycystic ovary syndrome? Human reproduction (Oxford, England), 1998, Volume: 13, Issue:1 Topics: Chromans; Diazoxide; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Thiazoles; Thiazolidinediones; Troglitazone	1998
Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance. Effects of troglitazone. Diabetologia, 1998, Volume: 41, Issue:5 Topics: Acetylcholine; Adult; Analysis of Variance; Biomarkers; Blood Glucose; Cardiovascular System; Case-Control Studies; Chromans; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Fasting; Female; Forearm; Glucose Clamp Technique; Hemodynamics; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Nitroprusside; Obesity; omega-N-Methylarginine; Reference Values; Regional Blood Flow; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilation; Vasodilator Agents	1998

Other Studies

36 other study(ies) available for thiazoles and Hyperinsulinism

Article	Year
Prior thiazolidinedione treatment preserves insulin sensitivity in normal rats during acute fatty acid elevation: role of the liver. Endocrinology, 2002, Volume: 143, Issue:12 Topics: Acyl Coenzyme A; Adiponectin; Animals; Blood Glucose; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Glucose; Glucose Clamp Technique; Heparin; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Liver; Male; Muscle, Skeletal; Phosphorylation; Pioglitazone; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones	2002
Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6 Topics: Animals; Benzazepines; Binding, Competitive; Blood Glucose; Blood Pressure; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Glucose; Hyperinsulinism; Hypoglycemic Agents; Insulin; Kidney; Kidney Tubules, Proximal; Male; Obesity; Rats; Rats, Zucker; Receptors, Dopamine D1; Rosiglitazone; Sodium-Potassium-Exchanging ATPase; Thiazoles; Thiazolidinediones	2002
Is programming of glucocorticoid receptor expression by prenatal dexamethasone in the rat secondary to metabolic derangement in adulthood? European journal of endocrinology, 2003, Volume: 148, Issue:1 Topics: Animals; Appetite; Body Weight; Corticosterone; Dexamethasone; Female; Gene Expression; Glucocorticoids; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Metformin; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Glucocorticoid; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones	2003
Troglitazone reduces activity of the Na+/H+ exchanger in fructose-fed borderline hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:1 Topics: Animals; Bezafibrate; Blood Glucose; Blood Platelets; Blood Pressure; Calcium; Chromans; Diet; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fructose; Hydrogen-Ion Concentration; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypolipidemic Agents; Insulin; Male; Propionates; Rats; Sodium-Hydrogen Exchangers; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Vasodilator Agents	2003
Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains. Endocrinology, 2003, Volume: 144, Issue:11 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Glucose Clamp Technique; Glucose Tolerance Test; Hyperglycemia; Hyperinsulinism; Insulin; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Piperazines; RNA, Messenger; Sulfonamides; Thiazoles	2003
Rosiglitazone reduces the accelerated neointima formation after arterial injury in a mouse injury model of type 2 diabetes. Circulation, 2003, Oct-21, Volume: 108, Issue:16 Topics: Animals; Blood Glucose; Carotid Arteries; Carotid Artery Injuries; Cells, Cultured; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Female; Homozygote; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Islets of Langerhans; Lipids; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Rosiglitazone; Thiazoles; Thiazolidinediones; Tunica Intima	2003
Metabolic effects of troglitazone on fat-induced insulin resistance in the rat. Metabolism: clinical and experimental, 1995, Volume: 44, Issue:11 Topics: Animals; Blood Pressure; Body Weight; Chromans; Dietary Fats; Eating; Glucose; Glucose Clamp Technique; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Liver; Male; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone	1995
New directions in treating insulin resistance. Hospital practice (1995), 1995, Sep-15, Volume: 30, Issue:9 Topics: Chromans; Diabetes Mellitus, Type 2; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Thiazoles; Thiazolidinediones; Troglitazone	1995
Effects of thiazolidinediones on glucocorticoid-induced insulin resistance and GLUT4 glucose transporter expression in rat skeletal muscle. Metabolism: clinical and experimental, 1993, Volume: 42, Issue:10 Topics: Animals; Benzopyrans; Blood Glucose; Deoxyglucose; Dexamethasone; Glucocorticoids; Glucose Transporter Type 4; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Isomerism; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Pioglitazone; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Tritium	1993
Effect of troglitazone, a new oral antidiabetic agent, on fructose-induced insulin resistance. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1995, Volume: 27, Issue:10 Topics: Aging; Animals; Blood Glucose; Body Weight; Chromans; Fructose; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone	1995
Malonyl coenzyme A and adiposity in the Dahl salt-sensitive rat: effects of pioglitazone. Metabolism: clinical and experimental, 1996, Volume: 45, Issue:4 Topics: Adipose Tissue; Animals; Blood Glucose; Blood Pressure; Dietary Carbohydrates; Dietary Fats; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Malonyl Coenzyme A; Muscle, Skeletal; Pioglitazone; Rats; Rats, Sprague-Dawley; Sodium Chloride; Thiazoles; Thiazolidinediones; Triglycerides	1996
Effect of troglitazone on leptin production. Studies in vitro and in human subjects. Diabetes, 1996, Volume: 45, Issue:9 Topics: Adipocytes; Adult; Animals; Blood Glucose; Cells, Cultured; Chromans; Fasting; Female; Glucose; Humans; Hyperinsulinism; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Leptin; Male; Middle Aged; Obesity; Protein Biosynthesis; Proteins; Thiazoles; Thiazolidinediones; Troglitazone	1996
"Glitazones", a prospect for non-insulin-dependent diabetes. Lancet (London, England), 1997, Jan-11, Volume: 349, Issue:9045 Topics: Chromans; Diabetes Mellitus, Type 2; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Pioglitazone; Thiazoles; Thiazolidinediones; Troglitazone	1997
TNF-alpha-induced insulin resistance in vivo and its prevention by troglitazone. Diabetes, 1997, Volume: 46, Issue:11 Topics: Adenosine Triphosphate; Animals; Blood Glucose; Chromans; Fatty Acids, Nonesterified; Glucose Clamp Technique; Hyperinsulinism; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha	1997
Direct vasodepressor effects of pioglitazone in spontaneously hypertensive rats. Pharmacology, 1998, Volume: 56, Issue:1 Topics: Animals; Arginine Vasopressin; Drug Evaluation, Preclinical; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin; Male; Norepinephrine; Pioglitazone; Potassium Chloride; Rats; Rats, Inbred SHR; Thiazoles; Thiazolidinediones; Vasodilator Agents	1998
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. The Journal of clinical investigation, 1998, Mar-15, Volume: 101, Issue:6 Topics: Adipocytes; Adipose Tissue; Animals; Apoptosis; Blood Glucose; Blotting, Northern; Body Weight; Chromans; DNA; DNA, Complementary; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Mesentery; Polymerase Chain Reaction; Proteins; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Retroperitoneal Space; RNA; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Troglitazone; Tumor Necrosis Factor-alpha	1998
Surgical and chemical approaches to regulate hyperinsulinemia after pancreas transplantation in rats. Transplantation proceedings, 1998, Volume: 30, Issue:2 Topics: Animals; Chromans; Diabetes Mellitus, Experimental; Drainage; Hyperinsulinism; Hypoglycemic Agents; Male; Pancreas Transplantation; Portal System; Rats; Rats, Inbred Lew; Thiazoles; Thiazolidinediones; Troglitazone	1998
Insulin-sensitising agents in polycystic-ovary syndrome. Lancet (London, England), 1998, Jan-31, Volume: 351, Issue:9099 Topics: Chromans; Controlled Clinical Trials as Topic; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Thiazoles; Thiazolidinediones; Treatment Outcome; Troglitazone	1998
Pharmacological profiles of a novel oral antidiabetic agent, JTT-501, an isoxazolidinedione derivative. European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3 Topics: 3T3 Cells; Administration, Oral; Animals; Blood Glucose; Cell Differentiation; Chromans; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Hyperinsulinism; Hypertriglyceridemia; Hypoglycemic Agents; Insulin; Isoxazoles; Male; Mice; Mice, Inbred Strains; Oxidation-Reduction; Pioglitazone; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Troglitazone	1999
Combination treatment with troglitazone, an insulin action enhancer, and pravastatin, an inhibitor of HMG-CoA reductase, shows a synergistic effect on atherosclerosis of WHHL rabbits. Atherosclerosis, 1999, Volume: 142, Issue:2 Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Blood Glucose; Cholesterol, LDL; Chromans; Coronary Vessels; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Glucose Tolerance Test; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperinsulinism; Hyperlipoproteinemia Type II; Hypoglycemic Agents; Insulin Resistance; Male; Pravastatin; Rabbits; Thiazoles; Thiazolidinediones; Troglitazone; Xanthomatosis	1999
Elimination of hyperinsulinemia after pancreas transplantation in rats. Transplantation proceedings, 1999, Volume: 31, Issue:5 Topics: Animals; Chromans; Hyperinsulinism; Hypoglycemic Agents; Male; Pancreas Transplantation; Portal System; Postoperative Complications; Rats; Rats, Inbred Lew; Thiazoles; Thiazolidinediones; Troglitazone	1999
Antidiabetic activity of white skinned sweet potato (Ipomoea batatas L.) in obese Zucker fatty rats. Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:1 Topics: Animals; Blood Glucose; Chromans; Fatty Acids, Nonesterified; Glucose Tolerance Test; Hyperinsulinism; Hypoglycemic Agents; Insulin; Islets of Langerhans; Lactic Acid; Male; Plant Extracts; Rats; Rats, Zucker; Solanaceae; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Weight Gain	2000
Pioglitazone attenuates basal and postprandial insulin concentrations and blood pressure in the spontaneously hypertensive rat. American journal of hypertension, 2000, Volume: 13, Issue:4 Pt 1 Topics: Animals; Area Under Curve; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Glucose; Hyperglycemia; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin; Male; Pioglitazone; Postprandial Period; Rats; Rats, Inbred SHR; Thiazoles; Thiazolidinediones	2000
Effects of troglitazone on blood concentrations of plasminogen activator inhibitor 1 in patients with type 2 diabetes and in lean and obese normal subjects. Diabetes, 2000, Volume: 49, Issue:4 Topics: Adult; Arteriosclerosis; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Female; Fibrinolysis; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Plasminogen Activator Inhibitor 1; Thiazoles; Thiazolidinediones; Tissue Plasminogen Activator; Troglitazone	2000
Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets. Proceedings of the National Academy of Sciences of the United States of America, 2000, Jul-18, Volume: 97, Issue:15 Topics: Adenoviridae; Animals; CCAAT-Enhancer-Binding Proteins; Chromans; DNA-Binding Proteins; Genetic Vectors; Hyperinsulinism; Hypolipidemic Agents; Islets of Langerhans; Leptin; Liver; Male; Nuclear Proteins; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation	2000
Troglitazone halts diabetic glomerulosclerosis by blockade of mesangial expansion. Kidney international, 2000, Volume: 58, Issue:6 Topics: Animals; Basement Membrane; Body Weight; Chondroitin Sulfate Proteoglycans; Chromans; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Fibrosis; Glomerular Mesangium; Hyperglycemia; Hyperinsulinism; Hypertriglyceridemia; Hypoglycemic Agents; Islets of Langerhans; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Troglitazone	2000
Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents. Molecular pharmacology, 2001, Volume: 59, Issue:4 Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression; Glucose Tolerance Test; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Liver; Male; Muscle, Skeletal; Nicotinic Acids; Obesity; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors	2001
Troglitazone stimulates pancreatic growth in congenitally CCK-A receptor-deficient OLETF rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:5 Topics: Aging; Amylases; Animals; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Fibrosis; Homeostasis; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipase; Male; Pancreas; Rats; Rats, Inbred OLETF; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Reference Values; Thiazoles; Thiazolidinediones; Troglitazone; Trypsin	2001
A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport. Proceedings of the National Academy of Sciences of the United States of America, 2001, Apr-24, Volume: 98, Issue:9 Topics: Animals; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Blood Glucose; Cell Line; Cholesterol; Cholesterol, HDL; Drug Design; Fasting; Fibroblasts; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Intestinal Mucosa; Intestines; Macaca mulatta; Macrophages; Male; Metabolic Diseases; Obesity; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Substrate Specificity; Thiazoles; Transcription Factors; Triglycerides	2001
Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability. Diabetes, 2001, Volume: 50, Issue:5 Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypertriglyceridemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Kinetics; Lipid Mobilization; Lipoproteins, VLDL; Liver; Male; Metabolic Clearance Rate; Muscle, Skeletal; Obesity; Oxidation-Reduction; Polyethylene Glycols; Postprandial Period; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Triglycerides	2001
A comparison of the effects of troglitazone and vitamin E on the fatty acid composition of serum phospholipids in an experimental model of insulin resistance. Physiological research, 2001, Volume: 50, Issue:3 Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Chromans; Disease Models, Animal; Fatty Acids; Female; Hyperinsulinism; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Rats; Rats, Mutant Strains; Rats, Wistar; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E	2001
The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes, 2002, Volume: 51, Issue:3 Topics: Adipocytes; Adipose Tissue; Blood Glucose; Body Composition; Calorimetry, Indirect; Diabetes Mellitus, Type 2; Fatty Acids; Glucose Clamp Technique; Glycated Hemoglobin; Glycerol; Humans; Hyperinsulinism; Insulin; Kinetics; Lipids; Lipolysis; Liver; Magnetic Resonance Spectroscopy; Microdialysis; Middle Aged; Muscle, Skeletal; Oxidation-Reduction; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides	2002
Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats. Diabetes, 2002, Volume: 51, Issue:4 Topics: Acetyl-CoA Carboxylase; Adipose Tissue; Animals; Blood Glucose; Body Weight; Dipeptidyl Peptidase 4; Drinking Behavior; Glucose; Glucose Tolerance Test; Glycogen Synthase; Hyperinsulinism; Insulin; Islets of Langerhans; Male; Muscle, Skeletal; Pentanoic Acids; Protease Inhibitors; Rats; Rats, Zucker; Reference Values; Thiazoles; Thiazolidines; Time Factors	2002
Characterization of CS-045, a new oral antidiabetic agent, II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice. Metabolism: clinical and experimental, 1991, Volume: 40, Issue:11 Topics: Administration, Oral; Animals; Blood Glucose; Chromans; Diabetes Mellitus; Glucagon; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Pancreas; Thiazoles; Thiazolidinediones; Troglitazone	1991
Effects of pioglitazone on glucose and lipid metabolism in Wistar fatty rats. Arzneimittel-Forschung, 1990, Volume: 40, Issue:3 Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Glucose Tolerance Test; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Muscles; Obesity; Pioglitazone; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidinediones	1990
Actions of novel antidiabetic agent englitazone in hyperglycemic hyperinsulinemic ob/ob mice. Diabetes, 1990, Volume: 39, Issue:10 Topics: 3-Hydroxybutyric Acid; Animals; Benzopyrans; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Glucagon; Glycerol; Hydroxybutyrates; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Kinetics; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Reference Values; Thiazoles; Thiazolidinediones; Triglycerides	1990