thiazoles has been researched along with Huntington Disease in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Bertoglio, D; Cybulska, K; Dominguez, C; Korat, Š; Liu, L; Miranda, A; Mrzljak, L; Munoz-Sanjuan, I; Skinbjerg, M; Staelens, S; Stroobants, S; Verhaeghe, J; Wyffels, L | 1 |
| Bi, C; Hu, B; Mi, T; Teng, Z; Wu, M; Wu, Y; Xia, L; Zhang, D; Zhu, W | 1 |
| Cregan, SP; Devries, RA; Ferguson, SS; Guimaraes, IM; Hamilton, A; Pires, RG; Ribeiro, FM | 1 |
| Boeira, SP; Bortolatto, CF; Jesse, CR; Nogueira, CW; Souza, LC; Wilhelm, EA | 1 |
| Abagyan, R; Casale, M; Dinkova-Kostova, AT; Kaltenbach, LS; Kazantsev, AG; Landers, JE; Leyfer, D; Lim, RG; Lo, DC; Luthi-Carter, R; Marsh, JL; Maxwell, MM; Meisel, L; Moniot, S; Naidu, SD; Pais, TF; Pallos, J; Quinti, L; Rauf, NA; Runne, H; Saiah, E; Steegborn, C; Thompson, LM; Van Kanegan, MJ | 1 |
| Kalonia, H; Kumar, A; Kumar, P | 1 |
| Cormier, K; Del Signore, SJ; Kosaras, B; Kowall, NW; Lee, J; McKee, A; Ratan, RR; Ryu, H | 1 |
| Kalonia, H; Kumar, A | 1 |
| Adame, A; Andrews-Zwilling, Y; Flik, G; Giorgini, F; Guidetti, P; Hsieh, EW; Huang, SY; Huang, Y; Laue, G; Lee, J; Louie, JY; Masliah, E; Moussaoui, S; Muchowski, JM; Muchowski, PJ; Notarangelo, FM; Patrick, C; Rassoulpour, A; Sathyasaikumar, KV; Scearce-Levie, K; Schwarcz, R; Truong, J; Wu, HQ; Wu, T; Zwilling, D | 1 |
| Kopito, RR; Melki, R; Quake, SR; Sourigues, Y; Streets, AM | 1 |
| Barnickel, G; Boeddrich, A; Böttcher, H; Bröcker, W; Dunkel, I; Engemann, S; Heiser, V; Herhaus, C; Lehrach, H; Lurz, R; Nordhoff, E; Rautenberg, S; Schugardt, N; Waelter, S; Wanker, EE | 1 |
| Bonelli, RM; Kapfhammer, HP; Mayr, BM; Niederwieser, G; Reisecker, F | 1 |
| Barker, AL; Bates, GP; Beunard, JL; Hockly, E; Holt, K; Lowden, PA; Moffitt, H; Moolman, DL; Revington, AP; Sathasivam, K; Sunshine, S; Tse, J; Wanker, EE; Woodman, B | 1 |
| Asami, T; Hirayasu, Y; Kato, D; Kawanishi, C; Nakamura, S; Roppongi, T; Shiozaki, K; Togo, T; Yoshimi, A | 1 |
| Calissano, P; Cicconi, S; Ciotti, MT; Gentile, A; Parasassi, T; Serafino, A | 1 |
| Cattaneo, E; Contini, A; Kazantsev, A; Leone, S; Moro, S; Mutti, C; Rigamonti, D; Sturlese, M | 1 |
| Klivényi, P; Vécsei, L | 1 |
| Boeddrich, A; Heiser, V; Lehrach, H; Lurz, R; Nordhoff, E; Scherzinger, E; Schugardt, N; Wanker, EE | 1 |
| Berthelier, V; Chen, S; Hamilton, JB; O'Nuallain, B; Wetzel, R | 1 |
1 review(s) available for thiazoles and Huntington Disease
| Article | Year |
|---|---|
[Neurodegeneration: aging and dementia. Etiopathogenic role of electron transport disorders. Therapeutic possibilities].
Topics: Aged; Aging; Alzheimer Disease; Calcium Channel Blockers; Cerebellar Diseases; Dementia; Electron Transport; Female; Humans; Huntington Disease; Lamotrigine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Parkinson Disease; Riluzole; Thiazoles; Triazines | 1997 |
18 other study(ies) available for thiazoles and Huntington Disease
| Article | Year |
|---|---|
Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington's Disease: a Longitudinal PET Study.
Topics: Animals; Benzamides; Disease Models, Animal; Huntington Disease; Mice, Inbred C57BL; Positron-Emission Tomography; Receptors, Metabotropic Glutamate; Thiazoles | 2020 |
A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs.
Topics: Amyloid Precursor Protein Secretases; Animals; Cell Line; Coculture Techniques; Corpus Striatum; Diamines; Human Embryonic Stem Cells; Humans; Huntington Disease; Mice; Mice, SCID; Neurogenesis; Neurons; Thiazoles | 2018 |
Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease.
Topics: Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Huntington Disease; Immunoenzyme Techniques; Intranuclear Inclusion Bodies; Mice; Mice, Knockout; Motor Activity; Pyridines; Real-Time Polymerase Chain Reaction; Receptor, Metabotropic Glutamate 5; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins; Thiazoles | 2014 |
Involvement of mGlu5 receptor in 3-nitropropionic acid-induced oxidative stress in rat striatum.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Glutathione Peroxidase; Glutathione Reductase; Huntington Disease; Male; Motor Activity; Neuroprotective Agents; Nitro Compounds; Oxidative Stress; Propionates; Pyridines; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Sodium-Potassium-Exchanging ATPase; Succinate Dehydrogenase; Thiazoles; Weight Loss | 2014 |
SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models.
Topics: Animals; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila; Huntington Disease; Neuroprotective Agents; NF-E2-Related Factor 2; Rats; Sirtuin 2; Structure-Activity Relationship; Thiazoles | 2016 |
Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carotenoids; Catalase; Coloring Agents; Electron Transport Complex IV; Huntington Disease; Lipid Peroxidation; Lycopene; Male; Motor Activity; NADH Dehydrogenase; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Nitric Oxide; Nitrites; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Signal Transduction; Succinate Dehydrogenase; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2009 |
Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice.
Topics: Adenosine Triphosphate; Age Factors; Aldehydes; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Imaging, Three-Dimensional; In Situ Nick-End Labeling; Indoles; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mitochondria; Neostriatum; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Oxidative Stress; Synapses; Tetrazolium Salts; Thiazoles; Trinucleotide Repeat Expansion | 2011 |
Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats.
Topics: Animals; Brain; Caspase 3; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Huntington Disease; Inflammation; Interleukin-6; Lipid Peroxidation; Locomotion; Male; Meloxicam; Mitochondria; Oxidative Stress; Pyrazoles; Quinolinic Acid; Rats; Rats, Wistar; Sulfonamides; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha | 2011 |
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.
Topics: Administration, Oral; Alzheimer Disease; Animals; Brain Chemistry; Disease Models, Animal; Female; Humans; Huntington Disease; Kynurenic Acid; Kynurenine 3-Monooxygenase; Male; Mice; Mice, Transgenic; Sulfonamides; Thiazoles | 2011 |
Simultaneous measurement of amyloid fibril formation by dynamic light scattering and fluorescence reveals complex aggregation kinetics.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Benzothiazoles; Fluorescence; Humans; Huntington Disease; Kinetics; Light; Parkinson Disease; Particle Size; Protein Structure, Secondary; Thiazoles | 2013 |
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.
Topics: Benzothiazoles; Blotting, Western; Cell Line; Electrophoresis, Polyacrylamide Gel; Exons; Fluorescent Antibody Technique, Indirect; Humans; Huntingtin Protein; Huntington Disease; Microscopy, Electron; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles | 2002 |
Ziprasidone in Huntington's disease: the first case reports.
Topics: Adult; Dopamine Antagonists; Female; Humans; Huntington Disease; Male; Middle Aged; Piperazines; Thiazoles | 2003 |
Evaluation of the benzothiazole aggregation inhibitors riluzole and PGL-135 as therapeutics for Huntington's disease.
Topics: Animals; Benzothiazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Genotype; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Neuroprotective Agents; Organ Culture Techniques; Riluzole; Thiazoles | 2006 |
Perospirone in treatment of Huntington's disease: a first case report.
Topics: Aged; Antipsychotic Agents; Anxiety; Dopamine Antagonists; Female; Humans; Huntington Disease; Indoles; Isoindoles; Mental Disorders; Neuropsychological Tests; Serotonin Antagonists; Thiazoles | 2007 |
Apoptotic death induces Abeta production and fibril formation to a much larger extent than necrotic-like death in CGNs.
Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Apoptosis; Benzothiazoles; Cerebellum; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes; Humans; Huntington Disease; Membrane Proteins; Microfilament Proteins; Microscopy, Electron, Transmission; Necrosis; Parkinson Disease; Reticulin; Thiazoles | 2007 |
SAR and QSAR study on 2-aminothiazole derivatives, modulators of transcriptional repression in Huntington's disease.
Topics: Gene Expression Regulation; Gene Library; Gene Silencing; Huntington Disease; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Repressor Proteins; Reproducibility of Results; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Transcription, Genetic | 2008 |
Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy.
Topics: Animals; Antibodies, Monoclonal; Benzoates; Benzothiazoles; Biphenyl Compounds; Congo Red; COS Cells; Gossypol; Humans; Huntingtin Protein; Huntington Disease; Melatonin; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Rifampin; Thiazoles | 2000 |
Amyloid-like features of polyglutamine aggregates and their assembly kinetics.
Topics: Amyloid beta-Peptides; Antibodies, Monoclonal; Benzothiazoles; Binding Sites, Antibody; Fluorescent Dyes; Freezing; Glutamine; Hot Temperature; Humans; Huntington Disease; Kinetics; Microscopy, Electron; Peptides; Protein Binding; Solubility; Thiazoles | 2002 |