Page last updated: 2024-08-21

thiazoles and Herpes Simplex Virus Infection

thiazoles has been researched along with Herpes Simplex Virus Infection in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19906 (20.00)18.7374
1990's2 (6.67)18.2507
2000's11 (36.67)29.6817
2010's10 (33.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Cannon, L; Farooq, H; Kingston, M; Tholouli, E; Ward, C1
Dereure, O; Du-Thanh, A; Lalande, M; Raison-Peyron, N1
Botta, M; Brai, A; Cagno, V; Canducci, F; Ceresola, ER; Dreassi, E; Ferrarese, R; Iovenitti, G; Lembo, D; Poli, G; Tintori, C; Zamperini, C1
Elbe-Bürger, A; Matiasek, J; Mildner, M; Popow-Kraupp, T; Schmidt, R; Schuster, C; Tajpara, P; Vierhapper, M1
Frost, AL; Itzhaki, RF; Wozniak, MA1
Biswas, S; Field, HJ; Sukla, S1
Birkmann, A; Biswas, S; Field, HJ; Goldner, T; Kropeit, D; Paulsen, D; Ruebsamen-Schaeff, H; Sukla, S; Welbers, A; Zimmermann, H1
Acosta, EP; James, SH; Larson, KB; Prichard, MN1
Birkmann, A; Zimmermann, H1
Birkmann, A; Biswas, S; Field, HJ; Tiley, LS; Zimmermann, H1
Abdel-Gawad, H; Badria, FA; Dawood, KM; Mohamed, HA1
Liu, ZT; Lv, R; Yu, H; Zhang, WQ1
Browne, A; Cordingley, MG; Dansereau, N; Duan, J; Faucher, AM; Liard, F; Liuzzi, M; Paris, W; Simoneau, B1
Hallenberger, S1
Kleymann, G1
Duan, J; Lambert, M; Liard, F; Paris, W1
Biswas, S; Field, HJ; Jennens, L2
Biswas, S; Field, HJ; Smith, C1
Dabrowska, H; Grzywa, Z; Moskalewska, K; Rózański, J1
Kozak, S; Michałowski, R; Olejnicka, Z; Urban, J1
Cisło, M; Dabrowska-Widera, J; Gasior-Chrzan, B; Wasik, F; Woytoń, A1
Laudańska, H; Niczyporuk, W; Szarmach, H; Wroński, A1
Colangelo, D; Dianzani, C; Guidotto, S; Tonso, E; Viano, I1
Konno, K; Shigeta, S; Sudo, K; Yokota, T1
Bolger, G; Cordingley, MG; Crute, JJ; Faucher, AM; Grygon, CA; Hargrave, KD; Kibler, P; Liuzzi, M; Simoneau, B1
Bach, U; Baumeister, J; Bender, W; Betz, UA; Eckenberg, P; Fischer, R; Frappa, I; Haebich, D; Handke, G; Hendrix, M; Henninger, K; Hewlett, G; Jensen, A; Keldenich, J; Kleymann, G; Kolb, J; Lockhoff, O; Mäben, J; Pevzner, V; Popp, A; Rübsamen-Waigmann, H; Schneider, U; Weber, O1
Betz, UA; Fischer, R; Hendrix, M; Kleymann, G; Rübsamen-Waigmann, H1
Carlson, DG; Scheetz ME, II; Schinitsky, MR1
Grafe, A; Liebig, H; Pfetzing, H1

Reviews

4 review(s) available for thiazoles and Herpes Simplex Virus Infection

ArticleYear
Helicase-primase inhibitors for herpes simplex virus: looking to the future of non-nucleoside inhibitors for treating herpes virus infections.
    Future medicinal chemistry, 2014, Volume: 6, Issue:1

    Topics: Antiviral Agents; DNA Helicases; DNA Primase; DNA Replication; Herpes Simplex; Humans; Oxadiazoles; Pyridines; Simplexvirus; Sulfonamides; Thiazoles; Viral Proteins

2014
Helicase-primase as a target of new therapies for herpes simplex virus infections.
    Clinical pharmacology and therapeutics, 2015, Volume: 97, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; DNA Helicases; DNA Primase; Drug Design; Drug Resistance, Viral; Herpes Simplex; Humans; Molecular Targeted Therapy; Oxadiazoles; Pyridines; Sulfonamides; Thiazoles; Viral Proteins

2015
HSV antivirals - current and future treatment options.
    Current opinion in virology, 2016, Volume: 18

    Topics: Acyclovir; Antiviral Agents; Clinical Trials, Phase II as Topic; DNA Helicases; DNA Primase; Drug Resistance, Viral; Herpes Genitalis; Herpes Simplex; Herpes Simplex Virus Vaccines; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Oxadiazoles; Pyridines; Sulfonamides; Thiazoles; Viral Proteins

2016
Helicase primase: targeting the Achilles heel of herpes simplex viruses.
    Antiviral chemistry & chemotherapy, 2004, Volume: 15, Issue:3

    Topics: Antiviral Agents; DNA Helicases; DNA Primase; Enzyme Inhibitors; Herpes Simplex; Humans; Models, Molecular; Pyridines; Simplexvirus; Sulfonamides; Thiazoles; Viral Proteins

2004

Other Studies

26 other study(ies) available for thiazoles and Herpes Simplex Virus Infection

ArticleYear
Use of pritelivir in refractory aciclovir-resistant herpes simplex virus type 2.
    International journal of STD & AIDS, 2021, Volume: 32, Issue:10

    Topics: Acyclovir; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Herpes Simplex; Herpesvirus 2, Human; Humans; Pyridines; Sulfonamides; Thiazoles

2021
Atypical and severe airborne isothiazolinone contact dermatitis mimicking Kaposi-Juliusberg syndrome.
    Contact dermatitis, 2017, Volume: 76, Issue:5

    Topics: Adolescent; Air Pollution, Indoor; Dermatitis, Atopic; Dermatitis, Contact; Diagnosis, Differential; Herpes Simplex; Humans; Male; Paint; Superinfection; Thiazoles

2017
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Drug Resistance, Viral; Female; HeLa Cells; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Molecular Structure; Pre-Exposure Prophylaxis; Rhodanine; Simplexvirus; Thiazoles; Vaginal Creams, Foams, and Jellies; Vero Cells; Virus Replication

2018
A Preclinical Model for Studying Herpes Simplex Virus Infection.
    The Journal of investigative dermatology, 2019, Volume: 139, Issue:3

    Topics: Acyclovir; Adult; Aged; Antiviral Agents; Biopsy, Needle; Case-Control Studies; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunohistochemistry; In Vitro Techniques; Male; Middle Aged; Models, Biological; Pyridines; Reference Values; Statistics, Nonparametric; Sulfonamides; Thiazoles; Virus Replication; Young Adult

2019
The helicase-primase inhibitor BAY 57-1293 reduces the Alzheimer's disease-related molecules induced by herpes simplex virus type 1.
    Antiviral research, 2013, Volume: 99, Issue:3

    Topics: Acyclovir; Alzheimer Disease; Amyloid beta-Peptides; Antiviral Agents; DNA Helicases; DNA Primase; Down-Regulation; Enzyme Inhibitors; Herpes Simplex; Herpesvirus 1, Human; Humans; Pyridines; Sulfonamides; tau Proteins; Thiazoles; Viral Proteins; Virus Replication

2013
Pharmacokinetics-pharmacodynamics of the helicase-primase inhibitor pritelivir following treatment of wild-type or pritelivir-resistant virus infection in a murine herpes simplex virus 1 infection model.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:7

    Topics: Animals; Antiviral Agents; DNA Primase; DnaB Helicases; Dose-Response Relationship, Drug; Drug Resistance, Viral; Female; Herpes Simplex; Herpesvirus 1, Human; Male; Mice; Mice, Inbred BALB C; Pyridines; Skin Diseases, Viral; Sulfonamides; Thiazoles; Viral Plaque Assay; Virus Replication

2014
Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity.
    Antiviral research, 2008, Volume: 80, Issue:1

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; DNA Helicases; DNA Primase; Drug Resistance, Viral; Enzyme Inhibitors; Herpes Simplex; Herpesvirus 1, Human; Humans; Mice; Mice, Inbred BALB C; Mutation; Pyridines; Sulfonamides; Thiazoles; Vero Cells; Viral Proteins; Virulence

2008
Synthesis and antiviral activity of new indole-based heterocycles.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:11

    Topics: Animals; Antiviral Agents; Cell Survival; Chlorocebus aethiops; Herpes Simplex; Herpesvirus 1, Human; Heterocyclic Compounds; Humans; Indoles; Thiazoles; Vero Cells

2010
Antiviral activity of recombinant cyanovirin-N against HSV-1.
    Virologica Sinica, 2010, Volume: 25, Issue:6

    Topics: Animals; Antiviral Agents; Bacterial Proteins; Biological Products; Carrier Proteins; Cell Survival; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Disease Models, Animal; DNA, Viral; Encephalitis, Viral; Female; Herpes Simplex; Herpesvirus 1, Human; Male; Mice; Recombinant Proteins; Survival Analysis; Tetrazolium Salts; Thiazoles; Vero Cells

2010
Oral bioavailability and in vivo efficacy of the helicase-primase inhibitor BILS 45 BS against acyclovir-resistant herpes simplex virus type 1.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:6

    Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Biological Availability; DNA Helicases; DNA Primase; Dose-Response Relationship, Drug; Drug Resistance, Viral; Enzyme Inhibitors; Female; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Nude; Pyridines; Thiazoles; Viral Proteins

2003
Antiviral therapies.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2004, Volume: 30 Suppl 1

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; Cytomegalovirus Infections; Drug Evaluation, Preclinical; Hepatitis B; Herpes Simplex; HIV Infections; Humans; Mice; Naphthalenesulfonates; Pyridines; Pyrimidines; Sulfonamides; Thiazoles; Virus Diseases

2004
A novel oral vehicle for poorly soluble HSV-helicase inhibitors: PK/PD validations.
    Pharmaceutical research, 2004, Volume: 21, Issue:11

    Topics: Acyclovir; Animals; Antiviral Agents; Chemical Phenomena; Chemistry, Physical; DNA Helicases; DNA Primase; Dose-Response Relationship, Drug; Drinking; Drug Stability; Enzyme Inhibitors; Excipients; Female; Herpes Simplex; Mice; Mice, Hairless; Mice, Nude; Pharmaceutical Vehicles; Pyridines; Simplexvirus; Thiazoles; Viral Proteins

2004
The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1.
    Antiviral research, 2007, Volume: 75, Issue:1

    Topics: 2-Aminopurine; Administration, Oral; Animals; Antiviral Agents; Brain Stem; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ear; Famciclovir; Herpes Simplex; Herpesvirus 1, Human; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Nude; Pyridines; Skin; Sulfonamides; Thiazoles

2007
Single amino acid substitutions in the HSV-1 helicase protein that confer resistance to the helicase-primase inhibitor BAY 57-1293 are associated with increased or decreased virus growth characteristics in tissue culture.
    Archives of virology, 2007, Volume: 152, Issue:8

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antiviral Agents; Chlorocebus aethiops; DNA Helicases; DNA Primase; Drug Resistance, Viral; Enzyme Inhibitors; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Pyridines; Sulfonamides; Thiazoles; Vero Cells; Viral Proteins; Virus Replication

2007
Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1.
    The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:2

    Topics: Adult; Amino Acid Sequence; Animals; Chlorocebus aethiops; DNA Helicases; Drug Resistance, Viral; Enzyme Inhibitors; Female; Genes, Viral; Herpes Simplex; Herpesvirus 1, Human; Humans; Male; Molecular Sequence Data; Polymorphism, Genetic; Pyridines; Sulfonamides; Thiazoles; Vero Cells; Viral Plaque Assay

2007
Wratizolin ITCL in the treatment of herpes simplex and recurrent and zoster.
    Archivum immunologiae et therapiae experimentalis, 1983, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Antiviral Agents; Child; Female; Herpes Simplex; Herpes Zoster; Humans; Male; Middle Aged; Ointments; Pyoderma; Recurrence; Skin Diseases, Infectious; Thiazoles; Warts

1983
Studies on the therapeutic effect of Wratizolin in selected dermatoses.
    Archivum immunologiae et therapiae experimentalis, 1983, Volume: 31, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Dermatitis, Atopic; Female; Herpes Simplex; Herpes Zoster; Humans; Male; Middle Aged; Molluscum Contagiosum; Psoriasis; Pyoderma; Skin Diseases; Skin Diseases, Infectious; Thiazoles; Warts

1983
Results of Wratizolin treatment of selected skin diseases with particular reference to those of viral etiology.
    Archivum immunologiae et therapiae experimentalis, 1983, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antiviral Agents; Child; Eczema; Female; Herpes Simplex; Herpes Zoster; Humans; Impetigo; Male; Middle Aged; Ointments; Skin Diseases; Skin Diseases, Infectious; Stomatitis, Aphthous; Thiazoles

1983
Clinical studies on the effectiveness of Wratizolin in the treatment of some dermatoses.
    Archivum immunologiae et therapiae experimentalis, 1983, Volume: 31, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Antiviral Agents; Cheilitis; Chickenpox; Child; Dermatitis, Contact; Drug Evaluation; Eczema; Herpes Simplex; Herpes Zoster; Humans; Middle Aged; Ointments; Pyoderma; Skin Diseases; Thiazoles

1983
In vivo antiviral effects of pidotimod.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:12A

    Topics: Adjuvants, Immunologic; Animals; Antiviral Agents; Cardiovirus Infections; Herpes Simplex; Influenza A virus; Male; Mengovirus; Mice; Orthomyxoviridae Infections; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Virus Diseases

1994
A screening system for antiviral compounds against herpes simplex virus type 1 using the MTT method with L929 cells.
    The Tohoku journal of experimental medicine, 1995, Volume: 176, Issue:3

    Topics: Animals; Antiviral Agents; Cell Line; Coloring Agents; Connective Tissue; Connective Tissue Cells; Drug Evaluation, Preclinical; Formazans; Herpes Simplex; Herpesvirus 1, Human; Indicators and Reagents; Mice; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Time Factors

1995
Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease.
    Nature medicine, 2002, Volume: 8, Issue:4

    Topics: Animals; Antiviral Agents; Disease Models, Animal; DNA Helicases; DNA Primase; Drug Design; Enzyme Inhibitors; Female; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; In Vitro Techniques; Mice; Mice, Hairless; Pyridines; Thiazoles; Viral Proteins

2002
New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease.
    Nature medicine, 2002, Volume: 8, Issue:4

    Topics: Acyclovir; Animals; Antiviral Agents; DNA Helicases; DNA Primase; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Guinea Pigs; Herpes Simplex; Humans; Infant, Newborn; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Pregnancy; Pyridines; Safety; Sulfonamides; Thiazoles; Viral Proteins

2002
Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:6

    Topics: Animals; Antibodies, Viral; Antiviral Agents; Blotting, Southern; DNA Helicases; DNA Primase; Drug Resistance, Microbial; Eye; Female; Herpes Simplex; Mice; Mice, Inbred BALB C; Mucous Membrane; Pyridines; Rats; Rats, Inbred Lew; Simplexvirus; Skin; Sulfonamides; Thiazoles

2002
Frentizole, a novel immunosuppressive, and azathioprine: their comparative effects on host resistance to Pseudomonas aeruginosa, Candida albicans, herpes simplex virus, and influenza (Ann Arbor) virus.
    Infection and immunity, 1977, Volume: 15, Issue:1

    Topics: Animals; Azathioprine; Benzothiazoles; Candida albicans; Candidiasis; Herpes Simplex; Immunosuppressive Agents; Male; Mice; Michigan; Orthomyxoviridae; Orthomyxoviridae Infections; Phenylurea Compounds; Pseudomonas aeruginosa; Pseudomonas Infections; Simplexvirus; Thiazoles

1977
[Experimental results with purposely synthetized substances for antiviral chemotherapy. 2. Additional 2-amino-4-phenylthiazoles, tetrahydrobenzthiazoles, 4-phenylimidazoles, and 8-hydroxyquinolines].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:6

    Topics: Animals; Antiviral Agents; Herpes Simplex; Hydroxides; Imidazoles; Orthomyxoviridae; Paramyxoviridae Infections; Poliovirus; Quinolines; Structure-Activity Relationship; Thiazoles; Vaccinia

1974