Page last updated: 2024-08-21

thiazoles and Fatty Liver

thiazoles has been researched along with Fatty Liver in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's1 (3.03)18.2507
2000's18 (54.55)29.6817
2010's10 (30.30)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Adarbes, V; de Muynck, K; Defrêne, E; Devisscher, L; Estivalet, C; Frank, AK; Geerts, A; Guillot, A; Heymann, F; Hundertmark, J; Lefere, S; Penners, C; Puengel, T; Tacke, F; Wettstein, G1
Ding, G; Ding, N; Gao, H; He, W; Li, H; Sheng, J; Wang, J; Yu, J; Zha, J1
Jiang, Y; Jin, X; Koniaris, LG; Milgrom, DP; Zhang, Z; Zimmers, TA1
de Oliveira, L; Graus-Nunes, F; Mandarim-de-Lacerda, CA; Rachid, TL; Silva-Veiga, FM; Souza-Mello, V1
Hotta, T; Iida, T; Imai, H; Inaba, T; Maeda, K; Mitani, I; Morinaga, H; Nakagawa, Y; Negoro, T; Ogoshi, Y; Oshida, S; Sakata, S; Sano, R; Tanaka, M; Ubukata, M1
Afford, SC; Attard, J; Bhogal, RH; Boteon, APCS; Boteon, YL; Hubscher, S; Mergental, H; Mirza, DF; Reynolds, G; Wallace, L1
Chew, GT; Sahebkar, A; Watts, GF1
Bekkers, M; Lindahl, U; Lindén, D; Lindstedt, E; Nilsson, R; Oscarsson, J; Princen, H; van der Hoorn, J; Voskuilen, M1
Hanley, AJ; Harris, SB; Retnakaran, R; Ye, C; Zinman, B1
Staels, B; Tailleux, A; Wouters, K1
Alonso, M; Alonso-Gascón, M; Baixeras, E; Bermúdez-Silva, FJ; López-Ogalla, J; Martínez, A; Pavón, FJ; Pérez-Valero, V; Rivera, P; Rodríguez de Fonseca, F; Romero-Cuevas, M; Santamaría, G; Serrano, A; Suarez, J; Vida, M1
Cho, EJ; Choi, R; Choi, YS; Chung, CH; Kim, BH; Kim, HM; Lee, EY; Lee, MY; Naowaboot, J; Shin, JY; Shin, YG; Yang, YC1
Inzucchi, SE; Petersen, KF; Shulman, GI1
Cooney, GJ; Ellis, B; Iglesias, MA; Jensen, PB; Kraegen, EW; Larsen, PJ; Sørensen, RV; Wassermann, K; Watson, DG; Wood, L; Ye, JM1
Brewer, B; Gavrilova, O; Gonzalez, FJ; Haluzik, M; Lambert, G; Matsusue, K; Reitman, ML; Ward, JM; Yim, SH1
Acerini, CL; Agostini, M; Bell, JD; Boiani, R; Chatterjee, VK; Cinti, S; Dixon, AK; Dunne, F; Gurnell, M; Jebb, SA; Karpe, F; O'Rahilly, S; Savage, DB; Tan, GD; Thomas, EL; Umpleby, AM; Vidal-Puig, A; Williams, RL1
Angulo, P1
Birmingham, J; Buckingham, RE; Changani, KK; Hockings, PD; O'Brien, P; Osborne, J; Reid, DG; Saeed, N; Toseland, CN1
Albanese, C; Brownlee, M; Donehower, LA; Fu, M; Harris, EL; Hulit, J; Johns, DC; Jones, JG; Li, Z; Neumeister, P; Novikoff, PM; Pattabiraman, N; Pestell, RG; Rohan, T; Sakamaki, T; Scherer, PE; Wang, C; Whitney, KD; Wu, K; Zhou, JN1
Bacon, BR; Brunt, EM; Neuschwander-Tetri, BA; Oliver, D; Wehmeier, KR1
Chen, TS; de Villiers, WJ; Im, HJ; McClain, CJ; Oz, HS1
Inada, Y; Kuroda, J; Maruyama, K; Nagasawa, T; Nakano, S; Shibata, N; Takahashi, T; Tamura, T; Yamazaki, Y1
Bortolan-Gianese, P; Dubini, F; Falchi, M; Ferrario, F; Marcucci, A1
Krentz, AJ1
Abe, S; Akiyama, T; Jia, DM; Otsuki, M; Tabaru, A1
Sanyal, AJ1
Battle, EH; Caldwell, SH; Hespenheide, EE; Iezzoni, JC; Redick, JA; Sheppard, BL1
Hata, S; Ikemoto, S; Inoue, Y; Katoh, S; Matsushima, M; Tajima, N; Yokoyama, J1
Maher, J1
Harano, Y1
Angulo, P; Lindor, KD1
Atzpodien, E; Bedoucha, M; Boelsterli, UA1
Burberi, S1

Reviews

4 review(s) available for thiazoles and Fatty Liver

ArticleYear
New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:4

    Topics: Acetates; Animals; Atherosclerosis; Chalcones; Cholesterol, HDL; Dyslipidemias; Fatty Liver; Fenofibrate; Humans; Insulin Resistance; Lipoproteins, HDL; Non-alcoholic Fatty Liver Disease; Peroxisome Proliferator-Activated Receptors; Propionates; Quinolines; Sulfonamides; Thiazoles; Triazoles; Triglycerides

2014
Roles of PPARs in NAFLD: potential therapeutic targets.
    Biochimica et biophysica acta, 2012, Volume: 1821, Issue:5

    Topics: Clinical Trials as Topic; Fatty Liver; Gene Expression; Humans; Inflammation; Liver; Non-alcoholic Fatty Liver Disease; Peroxisome Proliferator-Activated Receptors; Thiazoles; Triglycerides

2012
Current best treatment for non-alcoholic fatty liver disease.
    Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:5

    Topics: Antioxidants; Chromans; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Fatty Liver; Gemfibrozil; Humans; Hypolipidemic Agents; Liver Transplantation; Obesity; Thiazoles; Thiazolidinediones; Troglitazone; Weight Loss

2003
[Lipodystrophia].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 3

    Topics: Animals; Cardiomyopathy, Hypertrophic; Chromans; Diabetes Mellitus; Diagnosis, Differential; Fatty Liver; Humans; Hyperinsulinism; Hypertriglyceridemia; Insulin Resistance; Insulin-Like Growth Factor I; Lipid Metabolism; Lipodystrophy; Prognosis; Thiazoles; Thiazolidinediones; Troglitazone

2001

Trials

3 trial(s) available for thiazoles and Fatty Liver

ArticleYear
Discordant effects on central obesity, hepatic insulin resistance, and alanine aminotransferase of low-dose metformin and thiazolidinedione combination therapy in patients with impaired glucose tolerance.
    Diabetes, obesity & metabolism, 2012, Volume: 14, Issue:1

    Topics: Alanine Transaminase; Blood Glucose; Diabetes Mellitus, Type 2; Drug Combinations; Fatty Liver; Female; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Metformin; Obesity, Abdominal; Thiazoles; Waist-Hip Ratio

2012
Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone.
    Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Biopsy; Fatty Liver; Female; Humans; Insulin Resistance; Liver; Male; Middle Aged; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

2003
Troglitazone prevents the rise in visceral adiposity and improves fatty liver associated with sulfonylurea therapy--a randomized controlled trial.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:4

    Topics: Adipose Tissue; Aged; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fatty Liver; Female; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Obesity; Pilot Projects; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Troglitazone

2001

Other Studies

26 other study(ies) available for thiazoles and Fatty Liver

ArticleYear
Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages
    Journal of hepatology, 2020, Volume: 73, Issue:4

    Topics: Animals; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Fatty Liver; Fenofibrate; Hypolipidemic Agents; Liver; Liver Cirrhosis; Macrophages; Male; Mice; Peroxisome Proliferator-Activated Receptors; Thiazoles

2020
Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Diet, High-Fat; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Piperazines; Sulfonamides; Thiazoles

2021
Meloxicam increases epidermal growth factor receptor expression improving survival after hepatic resection in diet-induced obese mice.
    Surgery, 2018, Volume: 163, Issue:6

    Topics: Animals; Cyclooxygenase Inhibitors; Diet; ErbB Receptors; Fatty Liver; Hepatectomy; Hepatocytes; Liver Regeneration; Male; Meloxicam; Mice; Mice, Inbred C57BL; Mice, Obese; Thiazines; Thiazoles

2018
GW0742 (PPAR-beta agonist) attenuates hepatic endoplasmic reticulum stress by improving hepatic energy metabolism in high-fat diet fed mice.
    Molecular and cellular endocrinology, 2018, 10-15, Volume: 474

    Topics: Alanine Transaminase; Animals; Apoptosis; Body Weight; Cholesterol; Diet, High-Fat; Endoplasmic Reticulum Stress; Energy Intake; Energy Metabolism; Fatty Liver; Feeding Behavior; Glucose Tolerance Test; Hepatocytes; Inflammation; Insulin Resistance; Lipogenesis; Liver; Male; Mice, Inbred C57BL; Oxidation-Reduction; PPAR-beta; Protein Isoforms; Thiazoles

2018
Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Acetic Acid; Animals; Diabetes Mellitus; Drug Discovery; Enzyme Inhibitors; Fatty Liver; Liver; Male; Mice, Inbred C57BL; Obesity; Rats; Rats, Sprague-Dawley; Stearoyl-CoA Desaturase; Thiazoles

2018
Manipulation of Lipid Metabolism During Normothermic Machine Perfusion: Effect of Defatting Therapies on Donor Liver Functional Recovery.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2019, Volume: 25, Issue:7

    Topics: Allografts; Anthracenes; Butyrates; Colforsin; Fatty Liver; Feasibility Studies; Female; Humans; Lipid Metabolism; Liver; Liver Transplantation; Male; Middle Aged; Nicotinamide Phosphoribosyltransferase; Organ Preservation; Perfusion; Perylene; Pharmaceutical Solutions; Phenylurea Compounds; Reperfusion Injury; Thiazoles; Tissue and Organ Harvesting

2019
Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels.
    British journal of pharmacology, 2011, Volume: 162, Issue:7

    Topics: Aniline Compounds; Animals; Apolipoprotein E3; Atherosclerosis; Benzoates; Benzylamines; Cholesterol; Cytokines; Dose-Response Relationship, Drug; Fatty Liver; Female; Humans; Hypertriglyceridemia; Inflammation; Lipid Metabolism; Lipids; Liver; Liver X Receptors; Mice; Mice, Inbred C57BL; Mice, Transgenic; Orphan Nuclear Receptors; Thiazoles; Triglycerides

2011
Adiponectin promoter activator NP-1 reduces body weight and hepatic steatosis in high-fat diet-fed animals.
    American journal of physiology. Endocrinology and metabolism, 2012, Apr-01, Volume: 302, Issue:7

    Topics: Adiponectin; Analysis of Variance; Animals; Avoidance Learning; Blotting, Western; Body Weight; Cell Line; Diet, High-Fat; Dietary Fats; Eating; Fatty Liver; Glucose Tolerance Test; Lipid Metabolism; Liver; Male; Myoblasts; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA; Taste; Thiazoles; Weight Gain

2012
Peroxisome proliferator-activated receptor δ agonist attenuates hepatic steatosis by anti-inflammatory mechanism.
    Experimental & molecular medicine, 2012, Oct-31, Volume: 44, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Cytokines; Diabetes Mellitus; Fatty Liver; Glucose Tolerance Test; Hep G2 Cells; Humans; Insulin Resistance; Liver; Male; PPAR delta; Rats; Rats, Long-Evans; Thiazoles; Triglycerides

2012
Nonalcoholic fatty liver disease.
    The New England journal of medicine, 2002, Sep-05, Volume: 347, Issue:10

    Topics: Animals; Fatty Liver; Humans; Hypoglycemic Agents; Thiazoles

2002
PPARalpha /gamma ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly.
    American journal of physiology. Endocrinology and metabolism, 2003, Volume: 284, Issue:3

    Topics: Animals; Dietary Fats; Fatty Liver; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Muscle, Skeletal; Oxazines; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

2003
Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes.
    The Journal of clinical investigation, 2003, Volume: 111, Issue:5

    Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Fatty Liver; Hyperglycemia; Insulin Resistance; Leptin; Lipoprotein Lipase; Lipoproteins, VLDL; Liver; Mice; Mice, Inbred C57BL; Mice, Obese; Receptors, Cytoplasmic and Nuclear; Receptors, LDL; Receptors, Leptin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides

2003
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma.
    Diabetes, 2003, Volume: 52, Issue:4

    Topics: Abdomen; Adipose Tissue; Adult; Body Composition; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; Female; Gene Expression; Humans; Hyperlipidemias; Insulin Resistance; Kinetics; Liver; Magnetic Resonance Imaging; Male; Metabolic Syndrome; Middle Aged; Mutation; Neoplasm Proteins; Phenotype; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Tumor Suppressor Proteins

2003
Rapid reversal of hepatic steatosis, and reduction of muscle triglyceride, by rosiglitazone: MRI/S studies in Zucker fatty rats.
    Diabetes, obesity & metabolism, 2003, Volume: 5, Issue:4

    Topics: Animals; Fatty Liver; Hepatomegaly; Hypoglycemic Agents; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides

2003
Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.
    Molecular and cellular biology, 2003, Volume: 23, Issue:17

    Topics: 3T3 Cells; Animals; Breast; Breast Neoplasms; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Cyclin D1; Ecdysterone; Epithelial Cells; Fatty Liver; Female; Gene Expression Regulation; Humans; Mice; Mice, Mutant Strains; Mice, Transgenic; Models, Molecular; Mutation; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Reference Values; Repressor Proteins; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation

2003
Glutathione-enhancing agents protect against steatohepatitis in a dietary model.
    Journal of biochemical and molecular toxicology, 2006, Volume: 20, Issue:1

    Topics: Animals; Choline; Cytokines; Disease Models, Animal; Fatty Liver; Food, Formulated; Inflammation; Lipotropic Agents; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Thiazoles; Transaminases

2006
Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: Acyl-CoA Oxidase; Alanine Transaminase; Animals; Bezafibrate; Carnitine O-Palmitoyltransferase; Cholesterol, HDL; Choline; Diet; Dose-Response Relationship, Drug; Fatty Acid-Binding Proteins; Fatty Liver; Gene Expression; Interleukin-6; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptors; PPAR delta; RNA, Messenger; Thiazoles; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triglycerides

2006
[Transmethylating activity of arginine thiazolidinecarboxylate (ATCA) in acute CCL4 poisoning and diet-induced steatosis in the rat].
    Il Farmaco; edizione pratica, 1980, Volume: 35, Issue:6

    Topics: Animals; Arginine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Diet; Fatty Liver; Male; Methylation; Rats; Thiazoles; Thiazolidines

1980
Non-alcoholic steatohepatitis.
    Lancet (London, England), 1999, Oct-09, Volume: 354, Issue:9186

    Topics: Chromans; Contraindications; Diabetes Mellitus, Type 2; Fatty Liver; Hepatitis; Humans; Hypoglycemic Agents; Metformin; Thiazoles; Thiazolidinediones; Troglitazone

1999
Troglitazone prevents fatty changes of the liver in obese diabetic rats.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:10

    Topics: Age Factors; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Cholesterol; Chromans; Colon; Colonic Polyps; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Hyperlipidemias; Hypoglycemic Agents; Insulin; Liver; Male; Organ Size; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Thiazoles; Thiazolidinediones; Time Factors; Triglycerides; Troglitazone

2000
Insulin resistance and nonalcoholic steatohepatitis: fat or fiction?
    The American journal of gastroenterology, 2001, Volume: 96, Issue:2

    Topics: Chromans; Fatty Liver; Humans; Hypoglycemic Agents; Insulin Resistance; Lipolysis; Thiazoles; Thiazolidinediones; Troglitazone

2001
A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:2

    Topics: Adult; Alanine Transaminase; Chromans; Fatty Liver; Female; Humans; Hypoglycemic Agents; Obesity; Pilot Projects; Thiazoles; Thiazolidinediones; Troglitazone

2001
Antidiabetic treatment for NASH?
    Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:5

    Topics: Animals; CCAAT-Enhancer-Binding Proteins; Chromans; Diabetes Mellitus; DNA-Binding Proteins; Fatty Liver; Hepatitis; Hypoglycemic Agents; Islets of Langerhans; Leptin; Liver; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

2001
Severe cholestatic hepatitis from troglitazone in a patient with nonalcoholic steatohepatitis and diabetes mellitus.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:5

    Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Chromans; Diabetes Mellitus, Type 1; Fatty Liver; Female; Hepatitis; Humans; Hypoglycemic Agents; Thiazoles; Thiazolidinediones; Troglitazone

2001
Diabetic KKAy mice exhibit increased hepatic PPARgamma1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones.
    Journal of hepatology, 2001, Volume: 35, Issue:1

    Topics: Animals; Chromans; Diabetes Mellitus; Fatty Liver; Gene Expression; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Obesity; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation

2001
[Pharmacological research on thiazolidine-carboxylic acid].
    Bollettino chimico farmaceutico, 1975, Volume: 114, Issue:11

    Topics: Animals; Antidotes; Carboxylic Acids; Fatty Liver; Male; Rats; Thiazoles; Thimerosal; Troleandomycin

1975