thiazoles has been researched along with Experimental Neoplasms in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 86 (62.77) | 18.7374 |
| 1990's | 7 (5.11) | 18.2507 |
| 2000's | 24 (17.52) | 29.6817 |
| 2010's | 17 (12.41) | 24.3611 |
| 2020's | 3 (2.19) | 2.80 |
| Authors | Studies |
|---|---|
| Cheung, L; Flemming, CL; Fletcher, JI; Haber, M; Henderson, MJ; Hofmann, U; Huynh, T; Kamili, A; Murray, J; Norris, MD; Roundhill, EA; Schwab, M; Webber, HT; Yu, DMT | 1 |
| Chi, Z; Fang, X; Han, Z; Li, Y; Luan, Y; Sun, S; Wang, Q; Zhao, W | 1 |
| Dang, X; Fu, L; Hu, Y; Jiang, F; Lei, S; Lu, D; Luo, S; Wang, J; Yuan, C; Zhang, Y | 1 |
| Balce, DR; Dastidar, H; Ernst, M; Ewanchuk, BW; Gafuik, C; Jenne, C; Kim, DS; Lau, K; Mahoney, DJ; Naumenko, V; Rajwani, J; Rakic, A; Sikdar, S; Tailor, P; Yates, RM; Zemp, FJ; Zhang, C | 1 |
| Al-Ghorbani, M; Khanum, SA; Malojirao, VH; Mohammed, YHE; Prabhakar, BT; Thirusangu, P | 1 |
| Armstrong, SA; Barbosa, K; Bohlander, SK; Chen, BR; Deshpande, A; Deshpande, AJ; Dixon, J; Dutta, S; Ghosh, A; Sun, Y; Weetall, M | 1 |
| Dung, PT; Han, BW; Han, SB; Hong, JT; Hue, VT; Kim, Y; Nam, NH; Oanh, DT; Park, SH; Tung, TT | 1 |
| Arantes-Rodrigues, R; Colaço, A; Ferreira, R; Gaivão, I; Neuparth, MJ; Oliveira, P; Palmeira, C; Pinto-Leite, R; Pires, MJ; Santos, L | 1 |
| Chen, H; Dong, Y; Huang, H; Zhang, J; Zhang, W; Zhao, T; Zhu, J | 1 |
| Bao, XH; Fink-Baldauf, IM; Fukazawa, T; Hao, H; Maeda, Y; Matsuoka, J; Nakajima, M; Naomoto, Y; Nelson, S; Okui, T; Papoian, R; Seibel, W; Shimo, T; Takaoka, M; Takigawa, N; Tomono, Y; Whitsett, JA; Yamatsuji, T | 1 |
| Arnold, GJ; Fröhlich, T; Kubisch, R; Roidl, A; Schreiner, L; Vollmar, AM; von Schwarzenberg, K; Wagner, E | 1 |
| Gadaleta, C; Gadaleta, CD; Introna, M; Marech, I; Patruno, R; Ranieri, G; Zito, AF; Zizzo, N | 1 |
| Ding, Q; Fathallah-Shaykh, HM; Filippova, N; Friedman, GK; Gillespie, GY; Han, X; Langford, CP; Nabors, LB; Wheeler, CG; Wu, L; Yang, X; Zhang, W | 1 |
| Fujinaga, M; Hatori, A; Kawamura, K; Kumata, K; Nengaki, N; Shimoda, Y; Xie, L; Yamasaki, T; Yui, J; Zhang, MR; Zhang, Y | 1 |
| Chao, YS; Chen, CH; Chen, CP; Chen, CT; Chou, LH; Hsu, JT; Hsu, T; Huang, CL; Huang, YL; Jiaang, WT; Kuo, PC; Lin, WH; Liu, HE; Lu, CT; Song, JS; Yeh, TK; Yen, KJ; Yen, SC | 1 |
| Gadad, S; Kim, MY; Kim, SC; Nandu, TS; Park, MS; Song, KH | 1 |
| Allen, DA; Baskaran, S; Bui, M; Elling, RA; Flanagan, WM; Fung, AD; Hanan, EJ; Harris, S; Heumann, SA; Hoch, U; Jacobs, JW; Lam, J; Lawrence, CE; Lew, W; McDowell, RS; Nannini, MA; O'Brien, T; Oslob, JD; Romanowski, MJ; Shen, W; Silverman, JA; Sopko, MM; Tangonan, BT; Teague, J; Yoburn, JC; Yu, CH; Zhong, M; Zimmerman, KM | 1 |
| Li, Z; Xiong, Z; Yao, B; Zhang, D; Zhang, L | 1 |
| Davidson, FA; Jackson, RC; Kamei, H; Zheleva, D | 1 |
| Chen, X; Feng, Z; Jin, J; Li, X; Liu, H; Yuan, X; Zhang, H; Zhang, Y | 1 |
| Chang, CM; Chao, YS; Chen, CP; Chen, CT; Chen, TW; Chuu, JJ; Hsu, TA; Huang, CL; Hwang, DR; Li, WT; Lien, TW; Lin, CC; Lin, CH; Lin, HL; Song, JS; Tseng, HY | 1 |
| Aertgeerts, K; Arita, T; Hirose, M; Imada, T; Ishikawa, T; Kawamoto, T; Miyazaki, T; Ohashi, T; Okaniwa, M; Sang, BC; Sumita, A; Takagi, T; Tanaka, Y; Tsutsumi, S; Yabuki, M; Yano, J; Yoshida, S | 1 |
| Joo, SS; Kim, HJ; Kwon, HS; Lee, DI | 1 |
| Boven, E; Hoogsteen, IJ; Kohlhagen, G; Maliepaard, M; Pinedo, HM; Pommier, Y; Scheffer, GL; Scheper, RJ; Schlüper, HM; van Hattum, AH | 1 |
| Bibby, MC; Bradshaw, TD; Cooper, PA; Double, JA; Farmer, PB; Gaskell, M; Heydon, RT; Leong, CO; Martin, EA; Stevens, MF | 1 |
| Kutschy, P; Mezencev, R; Mojzis, J; Pilatova, M | 1 |
| CRANSTON, EM | 1 |
| FEDOSEEV, VM; SILAEV, AB; ZUBOVA, OV | 1 |
| INOUE, S; NAGANO, H; NODIFF, EA; SAGGIOMO, AJ | 1 |
| Kim, E; Kim, H; Kim, J; Kim, JH; Lee, H; Shin, HY; Sohn, JH; Yang, JM; Yun, CO | 1 |
| Atherton, J; Beebe, JS; Emerson, E; Finkelstein, M; Floyd, E; Foster, B; Gant, T; Goodwin, P; Harriman, S; Higdon, C; Hillerman, S; Jani, JP; Knauth, E; Kou, K; Marx, MA; Noe, MC; Rastinejad, F; Roberts, WG; Rossi, AM; Schaeffer, T; Soderstrom, C; Whalen, PM | 1 |
| Batorsky, R; Keller, KA; Kim, KS; Kimball, SD; Lee, FY; Lu, S; Misra, RN; Mulheron, JG; Sack, JS; Tokarski, JS; Webster, KR; Williams, DK; Xiao, HY | 1 |
| Bradshaw, TD; Fichtner, I; Hose, C; Monks, A; Stevens, MF | 1 |
| Bauder-Wüst, U; Eisenhut, M; Haberkorn, U; Mier, W; Mohammed, A; Schönsiegel, F; Wolf, M | 1 |
| Kajiura, H; Kidachi, Y; Ryoyama, K; Takata, H; Yamaguchi, H | 1 |
| Davis, JJ; Fang, B; Sasaki, J; Teraishi, F; Wu, S; Zhang, L; Zhu, HB | 1 |
| Bally, MB; Dos Santos, N; Edwards, K; Karlsson, G; Masin, D; Tardi, PG; Waterhouse, D | 1 |
| Braathen, LR; Córdoba, F; Kato, M; Nakashima, I; Vallan, C; von Felbert, V; Weis, J; Weissenberger, J | 1 |
| Giri, S; Rattan, R; Singh, AK; Singh, I | 1 |
| Blanco, G; Debeir, O; Gailly, P; Kiss, R; Kondo, S; Kondo, Y; Krstic, D; Lefranc, F; Mijatovic, T; Roland, I; Sauvage, S; Vasic, V | 1 |
| Slater, TF | 1 |
| Meister, A | 1 |
| Cheng, JX; Li, SZ; Lu, RS; Ma, HZ; Yu, XL | 1 |
| Croft, WA; Kamiryo, Y; Wang, CY | 1 |
| Brusick, DJ; Galloway, SM; Hinderer, RK; Jagannath, DR; Mann, SW; Myhr, B; Riddle, JC | 1 |
| Bartsch, H; Ohshima, H | 1 |
| Ambrus, JL; Bock, FG; Mirand, EA; Pine, MJ | 1 |
| Bryan, GT; Croft, WA; Wang, CY | 1 |
| Cohen, SM; Davis, BB; Fukushima, S; Mattammal, MB; Murasaki, G; Rapp, NS; Zenser, TV | 1 |
| Cohen, SM; Murasaki, G | 1 |
| Cohen, SM; Pauli, BU; Weinstein, RS | 1 |
| Arai, M; Cohen, SM; Friedell, GH; Fukushima, S; St John, M | 1 |
| Cohen, SM | 1 |
| Milligan, G; Strange, PG | 1 |
| Garner, CD; Hirose, M; Wang, CY | 1 |
| Betit-Yen, K; Gitterman, CO; Lee, G; Luell, S; Prendergast, JS; Skipski, VP; Stock, CC | 1 |
| Croft, MA; Croft, WA; Lower, GM; Paulus, KP; Wang, CY; Williams, JH | 2 |
| Hahn, FE | 1 |
| Mickey, DD; Mickey, GH; Murphy, WM; Niell, HB; Soloway, MS | 1 |
| Allhoff, EP; Chapman, CM; Hagen, IK; Lin, CW; Lin, JC; Mei, H; Proppe, KH; Prout, GR | 1 |
| Bassleer, R; De Pauw-Gillet, MC; Jamoulle, JC; Lapiere, CL; Marnette, JM; Massart, B; Wiliquet, P | 1 |
| Banks, AR; Hessek, E; Jones, T; Parks, RC | 1 |
| Armand, JP; Delsol, G; Marty, C; Neulat, I | 1 |
| Bryan, GT; Ertürk, E; Headley, DB; Klopp, RG; Michie, PM | 1 |
| Grossman, HB; Lesser, ML; Sonda, LP | 1 |
| Cohen, SM; Friedell, GH; Fukushima, S; Jacobs, JB | 1 |
| Rowland, RG; Wearly, DW | 1 |
| Hayashi, M; Hirose, M; Imaida, K; Ishihara, Y; Ito, H; Ito, N | 1 |
| McCallum, LW; Nissenkorn, I; Soloway, MS | 1 |
| Crooke, ST; Daskal, Y; DeFuria, MD; Soloway, MS | 1 |
| Balin, VV; Pliss, GB; Vlasov, NN | 1 |
| Bryan, GT; Matsushima, M | 1 |
| Kaneshiro, K; Kawashima, M; Kondo, T; Sato, Y; Wada, K; Yamauchi, M | 1 |
| Dos Santos, AV; Hussain, RF; Mansouri, M; Nouri, AM; Oliver, RT | 1 |
| Grau, MT; Ortiz, JA; Rives, A; Romero, A; Sacristán, A; Villamayor, F | 1 |
| Cannell, H; Nouri, AM; Tezabwala, BU | 1 |
| Grosu, AL; Molls, M; Stadler, P | 1 |
| Mito, K | 1 |
| Kulcsár, G | 1 |
| Aichholz, R; Blum, W; Brüggen, J; Flörsheimer, A; Kühnöl, J; O'Reilly, T; Ramstein, P | 1 |
| Chou, TC; Danishefsky, SJ; Guan, Y; Lee, C; O'Connor, OA; Stachel, SJ; Tong, WP; Zhang, ZG | 1 |
| Aktas, H; Grubissich, LM; Halperin, JA; Mortensen, RM; Palakurthi, SS | 1 |
| Alonso-Varona, A; Bilbao, J; Bilbao, P; Castro, B; del Olmo, M; Palomares, T | 1 |
| Alila, H; Baron, A; Bunn, PA; Chan, DC; Earle, KA; Helfrich, B; Nelson, P; Pamukcu, R; Piazza, G; Thompson, WJ; Whitehead, CM; Zeng, C; Zhao, TL | 1 |
| Bryan, GT; Cohen, SM; Headley, DB | 1 |
| Rogers, AE | 1 |
| Hyatt, CL; Javadpour, N; Soares, T | 1 |
| Arai, M; Brigham, SC; Jacobs, JB; Plotkin, GM; Wolf, G | 1 |
| Adolphs, HD; Kiel, H; Steffens, L; Thiele, J | 2 |
| Brooks, MH; Giner-Sorolla, A; Segarra, JT | 1 |
| Arai, M; Cohen, SM; Friedell, GH; Jacobs, JB | 3 |
| Droller, MJ; Perlmann, P; Schneider, MU | 1 |
| Alroy, J; Cohen, SM; Pauli, BU; Weinstein, RS | 1 |
| Hyatt, C; Marrone, JC; Martino, C; Soloway, MS | 1 |
| Ba, GN; Cao, TP; Dophuoc, H; Gak, JC; Jacquignon, P; Truhaut, R | 1 |
| Alroy, J; Friedell, GH; Jacobs, JB; Merk, FB; Pauli, BU; Weinstein, RS | 1 |
| Chirigos, MA; Luetzeler, J; Papamatheakis, JD; Schultz, RM | 1 |
| Matsushima, M | 1 |
| Murphy, GP; Williams, PD | 1 |
| Soloway, MS | 1 |
| Machón, Z | 1 |
| Alburn, HE; Fenichel, RL; Gregory, FJ | 1 |
| Bell, SC; Wei, PH | 1 |
| Bryan, GT; Hayashida, S; Pamukcu, AM; Wang, CY | 1 |
| Bryan, GT; Cohen, SM; Wittenberg, JF | 1 |
| Arai, H; Arai, M; Hishinuma, A; Kitamura, K; Kobayashi, T; Kohno, H; Kurakata, S; Nomoto, K; Tomatsu, M | 1 |
| Fliri, AF; Gallaschun, RJ; Goodwin, P; Grissom, M; Mangano, FM; McNiff, PA; Olson, TH; Schnur, RC; Singleton, DH; Sloan, DE | 1 |
| Twentyman, P; Wasserman, TH | 1 |
| Machoń, Z; Mordarski, M; Wieczorek, J | 1 |
| Luscombe, M; Twentyman, PR | 1 |
| Imaida, K; Wang, CY | 1 |
| Fujita, Y; Nagao, M; Ochiai, M; Sugimura, T; Tahira, T; Takayama, S; Wakabayashi, K | 1 |
| Bryan, GT; Cohen, SM; Ertürk, E | 5 |
| Ferioli, ME; Gazzola, GC; Guidotti, GG; Loreti, L | 1 |
| Atassi, SA; Bryan, GT; Cohen, SM; Ertürk, E; Price, JM; Yoshida, O | 1 |
| Renoux, G; Renoux, M | 1 |
| Ahl, CA; Daly, JJ; Prout, GR | 1 |
| Del Vecchio, PR; Malmgren, RA; Marrone, JA; Myers, GH; Soloway, MS | 1 |
| Bryan, GT; Cohen, SM; Ertürk, E; Lower, GM | 1 |
| Meisels, A; Schieweck, K; Schmidt-Ruppin, KH; Schott, E; Storni, A | 1 |
| Amaral, L; Pai, SH; Werthamer, S; Zak, FG | 1 |
| Brown, EV; Sanchorawala, CJ | 1 |
| Tiltman, AJ | 1 |
| Deliwala, CV; Modi, JD; Sarnis, SS | 1 |
| Golub', NI; Linnik, AB | 1 |
| Bryan, GT; Cohen, SM; Ertürk, E; Price, JM | 1 |
| Bryan, GT; Cohen, SM; Crovetti, AJ; Ertürk, E; Morris, JE; Price, JM; Von Esch, AM | 1 |
| Guthrie, J | 1 |
4 review(s) available for thiazoles and Experimental Neoplasms
| Article | Year |
|---|---|
Masitinib (AB1010), from canine tumor model to human clinical development: where we are?
Topics: Animals; Benzamides; Dogs; Humans; Neoplasms, Experimental; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Mas; Pyridines; Structure-Activity Relationship; Thiazoles | 2014 |
Antiproliferative and cancer chemopreventive activity of phytoalexins: focus on indole phytoalexins from crucifers.
Topics: Animals; Anticarcinogenic Agents; Brassicaceae; Chemoprevention; Disease Models, Animal; Humans; Indoles; Neoplasms, Experimental; Phytoalexins; Plant Extracts; Sesquiterpenes; Spiro Compounds; Terpenes; Thiazoles; Thiocarbamates | 2003 |
New aspects of glutathione biochemistry and transport--selective alteration of glutathione metabolism.
Topics: Animals; Biological Transport; Buthionine Sulfoximine; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Metabolism, Inborn Errors; Methionine Sulfoximine; Mice; Neoplasms, Experimental; Pyroglutamate Hydrolase; Radiation-Sensitizing Agents; Rats; Thiazoles | 1984 |
Nitrosatable precursors of mutagens in vegetables and soy sauce.
Topics: Animals; Benzylamines; Brassica; Chemical Phenomena; Chemistry; Glycine max; Indoles; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Nitrites; Thiazoles; Thiazolidines; Tyramine | 1985 |
1 trial(s) available for thiazoles and Experimental Neoplasms
| Article | Year |
|---|---|
Thiazolidine-4-carboxylic acid, a selective drug against human cancers.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Lethal Dose 50; Male; Mice; Neoplasms; Neoplasms, Experimental; Thiazoles; Thiazolidines | 1980 |
132 other study(ies) available for thiazoles and Experimental Neoplasms
| Article | Year |
|---|---|
CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Mercaptopurine; Mice; Mice, Transgenic; Molecular Structure; N-Myc Proto-Oncogene Protein; Neoplasms, Experimental; Neuroblastoma; Thiazoles | 2020 |
Design, synthesis and antitumor activity evaluation of novel HDAC inhibitors with tetrahydrobenzothiazole as the skeleton.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Microsomes, Liver; Molecular Structure; Neoplasms, Experimental; Rats; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured; Wound Healing; Zebrafish | 2021 |
Biological evaluation of mitochondria targeting small molecules as potent anticancer drugs.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Structure; Neoplasms, Experimental; Small Molecule Libraries; Structure-Activity Relationship; Thiazoles | 2021 |
Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms.
Topics: Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; Biomimetic Materials; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Combined Modality Therapy; Female; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondrial Proteins; Neoplasms, Experimental; Oncolytic Virotherapy; Oncolytic Viruses; Thiazoles; Treatment Outcome; Vesicular stomatitis Indiana virus | 2017 |
The Novel 4-Phenyl-2-Phenoxyacetamide Thiazoles modulates the tumor hypoxia leading to the crackdown of neoangiogenesis and evoking the cell death.
Topics: Acetamides; Animals; Antineoplastic Agents; Cell Death; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Neoplasms, Experimental; Neovascularization, Pathologic; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured; Tumor Hypoxia | 2018 |
Acute myeloid leukemia driven by the CALM-AF10 fusion gene is dependent on BMI1.
Topics: Animals; Heterocyclic Compounds, 2-Ring; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Transgenic; Neoplasms, Experimental; Oncogene Proteins, Fusion; Polycomb Repressive Complex 1; Proto-Oncogene Proteins; Thiazoles; U937 Cells; Xenograft Model Antitumor Assays | 2019 |
New benzothiazole/thiazole-containing hydroxamic acids as potent histone deacetylase inhibitors and antitumor agents.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; MCF-7 Cells; Mice; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Thiazoles | 2013 |
Meloxicam in the treatment of in vitro and in vivo models of urinary bladder cancer.
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Cell Cycle Checkpoints; Cell Proliferation; Comet Assay; Cyclooxygenase Inhibitors; DNA Damage; Flow Cytometry; Humans; Injections, Intraperitoneal; Male; Meloxicam; Mice; Mice, Inbred ICR; Microscopy; Neoplasms, Experimental; Precancerous Conditions; Thiazines; Thiazoles; Urinary Bladder Neoplasms | 2013 |
Paclitaxel-loaded poly(glycolide-co-ε-caprolactone)-b-D-α-tocopheryl polyethylene glycol 2000 succinate nanoparticles for lung cancer therapy.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cell Survival; Coumarins; Drug Delivery Systems; Humans; Lung Neoplasms; Mice; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Polyesters; Polyethylene Glycols; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Line, Tumor; Coumarins; Cytokines; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Midkine; Molecular Weight; Neoplasms, Experimental; Nerve Growth Factors; Phosphatidylinositol 3-Kinases; RNA, Small Interfering; Signal Transduction; Thiazoles; Tumor Burden; Vascular Endothelial Growth Factor A | 2013 |
V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo.
Topics: Animals; Blotting, Western; Cathepsin B; Cell Line, Tumor; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Lysosomes; Macrolides; MCF-7 Cells; Mice; Mice, Inbred BALB C; Neoplasms; Neoplasms, Experimental; Protein Transport; Receptor, IGF Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Thiazoles; Tumor Burden; Vacuolar Proton-Translocating ATPases | 2014 |
The role of Src family kinases in growth and migration of glioma stem cells.
Topics: AC133 Antigen; Animals; Antigens, CD; Cell Line, Tumor; Cell Movement; Cell Proliferation; CSK Tyrosine-Protein Kinase; Dasatinib; Glioma; Glycoproteins; Humans; Mice; Neoplasms, Experimental; Neoplastic Stem Cells; Peptides; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Pyrimidines; src-Family Kinases; Thiazoles; Up-Regulation | 2014 |
Synthesis and evaluation of 4-halogeno-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-[11C]methylbenzamide for imaging of metabotropic glutamate 1 receptor in melanoma.
Topics: Animals; Benzamides; Dose-Response Relationship, Drug; Humans; Male; Melanoma; Mice; Mice, Inbred C57BL; Molecular Imaging; Molecular Structure; Neoplasms, Experimental; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Thiazoles; Tissue Distribution | 2015 |
Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; fms-Like Tyrosine Kinase 3; Humans; Male; Mice; Mice, Inbred ICR; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Point Mutation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles | 2015 |
GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment.
Topics: Animals; Benzamides; Bone Morphogenetic Protein Receptors; Breast Neoplasms; Cell Line, Tumor; Diamines; Dioxoles; Female; Gene Expression Regulation, Neoplastic; Glycosylation; Guanine Nucleotide Exchange Factors; Humans; Lung; Lung Neoplasms; Mice; Mice, Nude; Mutation; N-Acetylgalactosaminyltransferases; Neoplasms, Experimental; Polypeptide N-acetylgalactosaminyltransferase; Pyrazoles; Quinolines; Receptors, Notch; Receptors, Transforming Growth Factor beta; Thiazoles | 2016 |
Discovery of a potent and selective aurora kinase inhibitor.
Topics: Animals; Antineoplastic Agents; Aurora Kinases; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Phenylurea Compounds; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Structure-Activity Relationship; Thiazoles | 2008 |
Effects of red light emitting diode on apoptosis of HeLa cells and suppression of implanted HeLa cells growth in mice.
Topics: Animals; Apoptosis; Calcium; Caspases; Cell Cycle; Flow Cytometry; HeLa Cells; Humans; Light; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Tetrazolium Salts; Thiazoles | 2009 |
An integrated pharmacokinetic-pharmacodynamic model for an Aurora kinase inhibitor.
Topics: Animals; Aurora Kinases; Cell Line, Tumor; Computer Simulation; Dose-Response Relationship, Drug; Drug Discovery; Humans; Mice; Models, Biological; Neoplasms, Experimental; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Thiazoles | 2010 |
Activity of the potent dual Abl/Src tyrosine kinase inhibitor FB2 against Bcr-Abl positive cell lines in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Separation; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fusion Proteins, bcr-abl; Humans; Immunoblotting; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms, Experimental; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Thiazoles; Xenograft Model Antitumor Assays | 2011 |
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Colchicine; Dose-Response Relationship, Drug; G2 Phase Cell Cycle Checkpoints; Humans; Imidazoles; Inhibitory Concentration 50; Male; Mice; Mice, Inbred DBA; Mice, Nude; Microtubules; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Thiazoles; Time Factors; Tubulin; Tubulin Modulators | 2012 |
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Mice; Microsomes; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Rats; Rats, Inbred F344; Structure-Activity Relationship; Thiazoles; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2012 |
Augmentation of macrophage antitumor activities and nitric oxide production by oregonin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Separation; Cytotoxicity Tests, Immunologic; Diarylheptanoids; In Vitro Techniques; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Neoplasms; Neoplasms, Experimental; Nitric Oxide; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity.
Topics: Acridines; Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Cell Division; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Isoquinolines; Membrane Glycoproteins; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Ovarian Neoplasms; Tetrahydroisoquinolines; Tetraspanin 29; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2002 |
Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Disease Models, Animal; DNA Adducts; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Thiazoles; Time Factors; Tumor Cells, Cultured | 2003 |
Ineffectiveness of five compounds on spontaneous mammary tumors of mice.
Topics: Animals; Chlorprothixene; Fluorouracil; Hydrocarbons; Mammary Neoplasms, Animal; Mice; Naphthoquinones; Neoplasms; Neoplasms, Experimental; Thiazoles | 1963 |
[STUDY OF THE ANTITUMOR ACTIVITY OF SOME DERIVATIVES OF 2,3-DI(ISOTHIURONIUM)-PROPANOL AND 2-IMINO-5-(ISOTHIURONIUM)-METHYLTHIAZOLIDINE].
Topics: 1-Propanol; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Isothiuronium; Neoplasms; Neoplasms, Experimental; Research; Sarcoma; Sarcoma, Experimental; Thiazoles; Toxicology | 1964 |
FLUORINE-CONTAINING POTENTIAL ANTICANCER AGENTS. II. SYNTHESES OF SOME TRIFLUOROMETHYLPURINES AND TRIFLUOROMETHYLTHIAZOLOPYRIMIDINES.
Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Fluorine; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; Research; Thiazoles | 1964 |
Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Base Sequence; beta-Galactosidase; Blotting, Western; Cell Line, Tumor; Coloring Agents; Gene Expression Regulation; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; HeLa Cells; Humans; Lac Operon; Mice; Mice, Nude; Models, Genetic; Molecular Sequence Data; Neoplasm Transplantation; Neoplasms, Experimental; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Sp1 Transcription Factor; Telomerase; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Up-Regulation | 2003 |
Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy.
Topics: Animals; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Kinetics; Male; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; NIH 3T3 Cells; Phosphorylation; Rats; Rats, Sprague-Dawley; Thiazoles; Urea; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2003 |
Synthesis and biological activity of N-aryl-2-aminothiazoles: potent pan inhibitors of cyclin-dependent kinases.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinases; Enzyme Inhibitors; Inhibitory Concentration 50; Leukemia; Mice; Neoplasms, Experimental; Protein Binding; Structure-Activity Relationship; Thiazoles; Treatment Outcome | 2004 |
The experimental antitumor agents Phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models.
Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cytochrome P-450 CYP1A1; DNA Adducts; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Prodrugs; Thiazoles; Transplantation, Heterologous | 2004 |
Alkylating benzamides with melanoma cytotoxicity.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Cell Line, Tumor; Cell Survival; Chlorambucil; Coloring Agents; Disease Models, Animal; Drug Delivery Systems; Drug Design; Ethylamines; HeLa Cells; Humans; Melanoma; Melanoma, Experimental; Mice; Models, Chemical; Neoplasms, Experimental; NIH 3T3 Cells; Procainamide; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Distribution | 2004 |
Anti-tumor activity of an enzymatically synthesized alpha-1,6 branched alpha-1,4-glucan, glycogen.
Topics: Amylose; Antineoplastic Agents; Glucans; Glycogen; Humans; Indicators and Reagents; Neoplasms, Experimental; Nitric Oxide; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2004 |
P-glycoprotein-independent apoptosis induction by a novel synthetic compound, MMPT [5-[(4-methylphenyl)methylene]-2-(phenylamino)-4(5H)-thiazolone].
Topics: Aniline Compounds; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Bone Marrow Cells; Caspases; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Enzyme Activation; Fibroblasts; Flow Cytometry; Genes, MDR; Genes, p53; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Paclitaxel; Proto-Oncogene Proteins c-jun; Thiazoles | 2005 |
Substantial increases in idarubicin plasma concentration by liposome encapsulation mediates improved antitumor activity.
Topics: Animals; Antibiotics, Antineoplastic; Area Under Curve; Buffers; Cell Line, Tumor; Cell Survival; Cholesterol; Drug Carriers; Drug Compounding; Drug Resistance, Neoplasm; Humans; Hydrogen-Ion Concentration; Idarubicin; Liposomes; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pharmaceutical Vehicles; Polyethylene Glycols; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous | 2005 |
5-aminolaevulinic acid photodynamic therapy in a transgenic mouse model of skin melanoma.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Fibrosis; Flow Cytometry; Humans; Light; Melanoma; Melanoma, Experimental; Mice; Mice, Transgenic; Neoplasm Metastasis; Neoplasms, Experimental; NIH 3T3 Cells; Photochemotherapy; Photosensitizing Agents; Skin Neoplasms; Tetrazolium Salts; Thiazoles; Trypan Blue | 2005 |
Rho/ROCK pathway as a target of tumor therapy.
Topics: Amides; Animals; Antineoplastic Agents; Apoptosis; Blotting, Southern; Blotting, Western; Caspases; Cell Survival; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Lovastatin; Male; Mevalonic Acid; Mice; Neoplasms; Neoplasms, Experimental; Polyisoprenyl Phosphates; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2006 |
Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells.
Topics: Adenosine Triphosphate; Animals; Apoptosis Regulatory Proteins; Beclin-1; Brain; Calcium; Cardenolides; Cell Movement; Cell Proliferation; Cells, Cultured; Glioblastoma; Green Fluorescent Proteins; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Proteins; Sodium-Potassium-Exchanging ATPase; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Thioproline.
Topics: Animals; Cell Membrane; Neoplasms, Experimental; Thiazoles; Thiazolidines | 1980 |
[Effects of 2, 2-dimethylthiazolidine hydrochloride on the radiosensitivity of transplantable mouse tumors (author's transl)].
Topics: Animals; Female; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Radiation Tolerance; Radiation-Protective Agents; Thiazoles | 1982 |
Carcinogenicity of 2-amino-4-(5-nitro-2-furyl) thiazole in rats by oral and subcutaneous administration.
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Squamous Cell; Diet; FANFT; Female; Histiocytoma, Benign Fibrous; Injections, Subcutaneous; Male; Neoplasms, Experimental; Rats; Skin Neoplasms; Stomach Neoplasms; Thiazoles; Urologic Neoplasms | 1982 |
Mutagenic evaluations of four rubber accelerators in a battery of in vitro mutagenic assays.
Topics: Benzothiazoles; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Clone Cells; DNA Repair; Escherichia coli; Humans; Lymphoma; Morpholines; Mutagens; Neoplasms, Experimental; Oxazines; Rubber; Salmonella; Thiazoles | 1983 |
Monitoring endogenous nitrosamine formation in man.
Topics: Animals; Environmental Monitoring; Feces; Humans; Kinetics; Mice; Neoplasms, Experimental; Nitrates; Nitrites; Nitrosamines; Nitroso Compounds; Rats; Risk; Thiazoles; Thiazolidines | 1984 |
Antitumor studies of 2-amino-2-thiazoline and other tumor-modifying agents.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Line; Dimethylhydrazines; Female; Methylcholanthrene; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Thiazoles; Thiazolidines | 1983 |
Tumor production in germ-free rats fed 5-nitrofurans.
Topics: Animals; Biotransformation; Carcinogens; FANFT; Female; Germ-Free Life; Intestines; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nitrofurans; Nitrofurantoin; Rats; Rats, Inbred Strains; Thiazoles | 1984 |
Aspirin inhibition of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced lesions of the urinary bladder correlated with inhibition of metabolism by bladder prostaglandin endoperoxide synthetase.
Topics: Animals; Aspirin; Biotransformation; Cyclooxygenase Inhibitors; FANFT; Hyperplasia; Male; Neoplasms, Experimental; Prostaglandins E; Rabbits; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1981 |
Co-carcinogenicity of sodium saccharin and N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide for the urinary bladder.
Topics: Animals; Cocarcinogenesis; Diet; FANFT; Growth; Male; Neoplasms, Experimental; Rats; Saccharin; Thiazoles; Tryptophan; Urinary Bladder Diseases; Urinary Bladder Neoplasms | 1983 |
Cellular changes in rat urinary bladder carcinomas induced by FANFT: a quantitative electron microscopic analysis.
Topics: Animals; Carcinogens; Cell Membrane; Cell Nucleus; Cytoplasm; Endoplasmic Reticulum; Epithelium; FANFT; Male; Microscopy, Electron; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
Long term dose response study of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced urinary bladder carcinogenesis.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; FANFT; Hyperplasia; Male; Neoplasms, Experimental; Papilloma; Prognosis; Rats; Rats, Inbred F344; Thiazoles; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
Promotion of urinary bladder carcinogenesis.
Topics: Animals; Carcinogens; FANFT; Mice; Neoplasms, Experimental; Organ Specificity; Thiazoles; Urinary Bladder Neoplasms; Urine | 1983 |
Reduction in accumulation of [3H]triphenylmethylphosphonium cation in neuroblastoma cells caused by optical probes of membrane potential. Evidence for interactions between carbocyanine dyes and lipophilic anions.
Topics: Animals; Benzothiazoles; Biological Transport; Carbocyanines; Cell Line; Fluorescent Dyes; Indicators and Reagents; Kinetics; Membrane Potentials; Mice; Neoplasms, Experimental; Neuroblastoma; Onium Compounds; Quinolines; Thiazoles; Tritium; Trityl Compounds | 1983 |
Effect of phenobarbital on the carcinogenesis of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in rats.
Topics: Animals; Carcinogens; Drug Interactions; Drug Synergism; FANFT; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms | 1983 |
Possible relationship between glycosphingolipids and the formation of metastasis in certain human experimental tumors.
Topics: Animals; Carcinoma, Squamous Cell; Chick Embryo; Gangliosides; Glycosphingolipids; Humans; Neoplasm Metastasis; Neoplasms, Experimental; Quinazolines; Sarcoma; Thiazoles | 1980 |
13-cis-retinoic acid: effect on urinary bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in Fischer rats.
Topics: Animals; Butylated Hydroxytoluene; Carcinogens; FANFT; Female; Isomerism; Isotretinoin; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Tretinoin; Urinary Bladder Neoplasms | 1981 |
In vitro characterization of four N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide (FANFT) induced mouse bladder tumors.
Topics: Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Line; FANFT; Karyotyping; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Thiazoles; Urinary Bladder Neoplasms | 1982 |
Rat bladder isograft model for focal carcinoma.
Topics: Animals; Carcinoma, Transitional Cell; FANFT; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Thiazoles; Transplantation, Isogeneic; Urinary Bladder Neoplasms | 1982 |
[Effects of L-thiazolidine-4-carboxylic acid (thiaproline) on cancer cells in culture].
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1982 |
Thioproline: an inhibitor of chemical carcinogenesis.
Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Female; Methylcholanthrene; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Thiazoles; Thiazolidines | 1982 |
The effect of thioproline on transplanted tumors in nude mice.
Topics: Animals; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Thiazoles; Thiazolidines; Transplantation, Heterologous | 1980 |
Temporal comparisons of immune status and target organ histology in mice fed carcinogenic 5-nitrofurans and their nornitro analogs.
Topics: Animals; Antibody Formation; Carcinogens; Diet; FANFT; Female; Furans; Immunity, Cellular; Leukemia, Experimental; Lymphoid Tissue; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrofurans; Thiazoles; Time Factors; Urinary Bladder Neoplasms | 1981 |
The effect of single dose N-methyl-N-nitrosourea on bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide in rats.
Topics: Animals; Body Weight; Carcinoma, Papillary; Carcinoma, Transitional Cell; FANFT; Female; Hyperplasia; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1981 |
Effect of L-tryptophan and sodium saccharin on urinary tract carcinogenesis initiated by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
Topics: Animals; Carcinoma, Transitional Cell; Cocarcinogenesis; FANFT; Male; Neoplasms, Experimental; Rats; Saccharin; Thiazoles; Tryptophan; Urinary Bladder Neoplasms | 1981 |
Urinary diversion and systemic chemotherapy in the treatment of experimental early neoplastic lesions of the bladder.
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Papillary; Cyclophosphamide; Male; Neoplasms, Experimental; Nitrofurans; Organ Size; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Diversion | 1981 |
Synthetic retinamides: effect on urinary bladder carcinogenesis by FANFT in Fischer rats.
Topics: Animals; Body Weight; FANFT; Female; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Tretinoin; Urinary Bladder Neoplasms | 1981 |
Effects of chloroform and dimethylnitrosamine on renal carcinogenesis in unilaterally nephrectomized rats fed formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide.
Topics: Animals; Body Weight; Carcinogens; Chloroform; Dimethylnitrosamine; Kidney Neoplasms; Male; Neoplasms, Experimental; Nephrectomy; Nitrofurans; Organ Size; Rats; Rats, Inbred F344; Thiazoles | 1981 |
Comparison between a purified and standard diet on FANFT-induced murine bladder cancer.
Topics: Animal Feed; Animals; Body Weight; Diet; FANFT; Female; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Organ Size; Thiazoles; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1981 |
Morphological effects of mitomycin C administered intravesically to normal mice and mice with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induce bladder neoplasms.
Topics: Animals; Epithelium; FANFT; Female; Mice; Microscopy, Electron; Mitomycins; Neoplasms, Experimental; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1980 |
[Epithelial bladder tumor induction in rats with N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide].
Topics: Animals; Carcinoma, Transitional Cell; FANFT; Formamides; Male; Neoplasms, Experimental; Papilloma; Rats; Thiazoles; Time Factors; Urinary Bladder Neoplasms | 1980 |
Early induction of mouse urinary bladder ornithine decarboxylase activity by rodent vesical carcinogens.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Carcinogens; Enzyme Induction; Epithelium; FANFT; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Thiazoles; Tretinoin; Urinary Bladder; Urinary Bladder Neoplasms | 1980 |
[Chemosensitivity test with endoscopic biopsy specimens].
Topics: Animals; Antineoplastic Agents; Biopsy; Drug Screening Assays, Antitumor; Endoscopy, Gastrointestinal; Humans; Intestinal Neoplasms; Neoplasms, Experimental; Sensitivity and Specificity; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Intensity of class I antigen expression on human tumour cell lines and its relevance to the efficiency of non-MHC-restricted killing.
Topics: Antigens, Neoplasm; Cell Death; Cytokines; Histocompatibility Antigens Class I; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Major Histocompatibility Complex; Neoplasms, Experimental; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 1993 |
Twenty-four-month oral carcinogenicity study of ebrotidine in rats.
Topics: Animals; Benzenesulfonates; Body Weight; Carcinogens; Dose-Response Relationship, Drug; Feeding Behavior; Female; Gastric Mucosa; Histamine H2 Antagonists; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Risk; Sex Factors; Survival Rate; Thiazoles; Time Factors; Tissue Distribution | 1998 |
Quantification of metabolic activity in tumour fragments.
Topics: Animals; Colorimetry; Coloring Agents; Cricetinae; Female; Humans; Male; Neoplasm Transplantation; Neoplasms, Experimental; Tetrazolium Salts; Thiazoles | 1998 |
[A chemical inhibitor of p53 that protects mice from the side effects of cancer treatment].
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Combined Modality Therapy; Drug Evaluation, Preclinical; Mice; Neoplasms, Experimental; Radiotherapy; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
A needle-type immunotherapeutic system incorporating laser light and platonin in combination with ethanol injection in the treatment of cancer growing in deep organs.
Topics: Animals; Colonic Neoplasms; Coloring Agents; Ethanol; Immunotherapy; Injections; Lasers; Lymphocytes; Macrophage Activation; Male; Mice; Mice, Inbred Strains; Needles; Neoplasms, Experimental; Photosensitizing Agents; Quinolinium Compounds; Survival Rate; Thiazoles | 1999 |
Synergistic potentiating effect of D(+)-mannose, orotic, and hippuric acid sodium salt on selective toxicity of a mixture of 13 substances of the circulatory system in culture for various tumor cell lines.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Line; Colorimetry; Dogs; Drug Resistance, Multiple; Hippurates; Humans; Macaca mulatta; Mannose; Mice; Multiple Myeloma; Neoplasms, Experimental; Orotic Acid; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
In vivo metabolism of epothilone B in tumor-bearing nude mice: identification of three new epothilone B metabolites by capillary high-pressure liquid chromatography/mass spectrometry/tandem mass spectrometry.
Topics: Animals; Antineoplastic Agents; Biotransformation; Chromatography, High Pressure Liquid; Epothilones; Epoxy Compounds; Female; Humans; Liver; Mass Spectrometry; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Thiazoles | 2001 |
The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice.
Topics: Animals; Antineoplastic Agents; Epothilones; Humans; Lactones; Mice; Mice, Nude; Microtubules; Neoplasm Transplantation; Neoplasms, Experimental; Thiazoles; Transplantation, Heterologous | 2001 |
Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor gamma and mediated by inhibition of translation initiation.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Calcium; Cell Division; Cyclin G; Cyclin G1; Cyclins; DNA, Neoplasm; Eukaryotic Initiation Factor-2; Humans; Ligands; Male; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Phosphorylation; Protein Biosynthesis; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured | 2001 |
L-2-Oxothiazolidine-4-carboxylate reverses the tumour growth-promoting effect of interleukin-2 and improves the anti-tumour efficacy of biochemotherapy in mice bearing B16 melanoma liver metastases.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Female; Glutathione; Interleukin-2; Liver; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors; Tumor Cells, Cultured | 2002 |
Exisulind in combination with docetaxel inhibits growth and metastasis of human lung cancer and prolongs survival in athymic nude rats with orthotopic lung tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Docetaxel; Drug Administration Schedule; Female; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Mediastinal Neoplasms; Neoplasms, Experimental; Paclitaxel; Rats; Rats, Nude; Sulindac; Survival Rate; Taxoids; Tetrazolium Salts; Thiazoles | 2002 |
Suppression of antibody-mediated and cell-mediated murine immunity by the carcinogen N-[4-(5-nitro-2-furyl)-2-thiazolyl]acetamide.
Topics: Animals; Antibody-Producing Cells; Carcinogens; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Graft vs Host Reaction; Immunity; Immunity, Cellular; Immunosuppressive Agents; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrofurans; Thiazoles; Urinary Bladder Neoplasms | 1977 |
Variable effects of a lipotrope-deficient, high-fat diet on chemical carcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Aflatoxins; Alkynes; Animals; Carcinogens; Diet; Dietary Fats; Formamides; Lipotropic Agents; Male; Methylnitronitrosoguanidine; Neoplasms, Experimental; Rats; Thiazoles | 1975 |
Immunologic features of a carcinogen-induced murine bladder cancer: in vivo and in vitro studies.
Topics: Animals; Antigens, Neoplasm; Cross Reactions; Cytotoxicity, Immunologic; Epitopes; FANFT; Female; Fetus; Immunity; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Pregnancy; Thiazoles; Urinary Bladder Neoplasms | 1979 |
Uridine 5'-diphosphate galactose: glycoprotein galactosyl transferase activity in exfoliated bladder epithelial cells in rats fed N-(4-(5-nitro-2-furyl)-2-thiazolyl) formamide.
Topics: Animals; beta-N-Acetylglucosaminylglycopeptide beta-1,4-Galactosyltransferase; Epithelial Cells; Epithelium; FANFT; Female; Galactosyltransferases; Humans; Hyperplasia; Male; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms; Urine | 1977 |
Biological behavior of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide induced carcinoma of the transitional epithelium in the rat.
Topics: Animals; Carcinoma, Transitional Cell; FANFT; Female; Kidney Neoplasms; Kidney Pelvis; Neoplasm Staging; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder Neoplasms | 1978 |
Synthesis and screening of 8-(4'-thiazolyl)purines.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Female; Immunity; Lymphocytes; Mice; Neoplasms, Experimental; Purines; Simplexvirus; Thiazoles; Virus Replication | 1978 |
Effect of dose on urinary bladder carcinogenesis induced in F344 rats by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
Topics: Animals; Dose-Response Relationship, Drug; Epithelium; FANFT; Hyperplasia; Male; Microscopy, Electron, Scanning; Microvilli; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms | 1979 |
Enhancement of natural and antibody-dependent lymphocyte cytotoxicity by drugs which inhibit prostaglandin production by tumor target cells.
Topics: Antibody-Dependent Cell Cytotoxicity; Aspirin; Cell Line; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Humans; Indomethacin; Lymphocytes; Neoplasms, Experimental; Prostaglandin Antagonists; Thiazoles; Time Factors | 1978 |
Induction of transitional cell carcinoma of the urinary bladder in rats by feeding N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide. Histological and ultrastructural findings.
Topics: Animals; Carcinoma, Transitional Cell; Disease Models, Animal; Epithelium; FANFT; Female; Neoplasms, Experimental; Organ Size; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1978 |
Desmosome ultrastructure and biological behavior of chemical carcinogen-induced urinary bladder carcinomas.
Topics: Animals; Carcinoma, Transitional Cell; Cell Adhesion; Desmosomes; FANFT; Male; Microscopy, Electron; Neoplasm Invasiveness; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder Neoplasms | 1978 |
Immunogenicity of N-[-4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced bladder cancer.
Topics: Animals; Antigens, Neoplasm; Carcinoma, Transitional Cell; Cross Reactions; FANFT; Female; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Thiazoles; Urinary Bladder Neoplasms | 1978 |
[Inhibitory effect of ellipticine (dimethyl-5,11-(6H) pyrido (4,3-b) carbazole on the induction of liver cancer by BT6 (N,N-dimethyl-p-(benzothiazolylazo) analine) and its effect on the levels of cytochrome P450 and arginase activity].
Topics: Alkaloids; Animals; Arginase; Cytochrome P-450 Enzyme System; Ellipticines; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Thiazoles; Time Factors | 1976 |
A long-term study of reversible and progressive urinary bladder cancer lesions in rats fed N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
Topics: Animals; Epithelium; FANFT; Hyperplasia; Male; Microscopy, Electron, Scanning; Neoplasms, Experimental; Precancerous Conditions; Rats; Thiazoles; Time Factors; Urinary Bladder Neoplasms | 1977 |
Malignant transformation of urinary bladder in humans and in N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-exposed Fischer rats: ultrastructure of the major components of the permeability barrier.
Topics: Animals; Cell Membrane; Cell Membrane Permeability; Cell Transformation, Neoplastic; Epithelium; FANFT; Humans; Intercellular Junctions; Male; Microscopy, Electron; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1977 |
Association of macrophage activation with antitumor activity by synthetic and biological agents.
Topics: Animals; BCG Vaccine; Benzimidazoles; Cytotoxicity Tests, Immunologic; Dextrans; Immunotherapy; Levamisole; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental; Poly I-C; Polysaccharides; Pyran Copolymer; Thiazoles; Thymosin; Tilorone; Typhoid-Paratyphoid Vaccines | 1977 |
[The role of L-tryptophan's promoting factor on tumorgenesis in the urinary bladder. 2. Urinary bladder carcinogenicity of FANFT (initiating factor) and L-tryptophan (promoting factor) in mice (author's transl)].
Topics: Animals; FANFT; Female; Mice; Neoplasms, Experimental; Thiazoles; Tryptophan; Urinary Bladder Neoplasms | 1977 |
Experimental bladder tumor induction, propagation, and therapy.
Topics: Administration, Oral; Animals; Carcinoma, Transitional Cell; FANFT; Female; Mice; Mice, Inbred C3H; Mitomycins; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thiazoles; Urinary Bladder Neoplasms | 1976 |
FANFT-induced bladder tumors.
Topics: Animals; Disease Models, Animal; FANFT; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Thiazoles; Urinary Bladder Neoplasms | 1976 |
Light and scanning electron microscopy of exfoliated bladder epithelial cells in rats fed N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide.
Topics: Animals; Epithelial Cells; Epithelium; FANFT; Hyperplasia; Male; Microscopy, Electron, Scanning; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms; Urine | 1976 |
Synthesis and biological properties of derivatives of 3-methyl-5-aminoisothiazolo-4-carboxylic acid.
Topics: Animals; Carboxylic Acids; Carcinoma, Ehrlich Tumor; Cell Survival; Lymphoma; Neoplasms, Experimental; Structure-Activity Relationship; Thiazoles | 1976 |
Anti-tumour and anti-metastatic activity of 3-(P-Chlorophenyl)-2,3-Dihydro-3-Hydroxythiazolo (3,2-A)-Benzimidazole-2-acetic acid (WY-13,876).
Topics: Animals; Anthelmintics; Antilymphocyte Serum; Antineoplastic Agents; Benzimidazoles; Cyclophosphamide; Fluorouracil; Lethal Dose 50; Levamisole; Lung Neoplasms; Male; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; T-Lymphocytes; Thiazoles; Transplantation, Isogeneic | 1976 |
Syntheses of heterocylic fused thiazole acetic acids. 2.
Topics: Acetates; Animals; Antidepressive Agents; Antineoplastic Agents; Antitubercular Agents; Bridged-Ring Compounds; Humans; Mice; Neoplasms, Experimental; Reserpine; Thiazoles | 1976 |
Enhancing effect of allopurinol on the induction of bladder cancer in rats by n-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
Topics: Allopurinol; Animals; Carcinoma, Transitional Cell; Cytosol; Drug Synergism; FANFT; Female; Liver; Neoplasms, Experimental; Nitrate Reductases; Rats; Sulfhydryl Compounds; Thiazoles; Time Factors; Tryptophan; Urinary Bladder Neoplasms | 1976 |
Effect of avitaminosis A and hypervitaminosis A on urinary bladder carcinogenicity of N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide.
Topics: Animals; Body Weight; FANFT; Female; Metaplasia; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Diseases; Urinary Bladder Neoplasms; Vitamin A; Vitamin A Deficiency | 1976 |
Modulation of the immune response to tumors by a novel synthetic compound, (4R)-3-benzoyl-N-[(1R)-1-phenylethyl]-4-thiazolidinecarboxamide (RS-0481).
Topics: Adjuvants, Immunologic; Animals; Bone Marrow; Colony-Stimulating Factors; Female; Hypersensitivity, Delayed; Interleukin-2; Killer Cells, Natural; Macrophage Activation; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Neoplasms, Experimental; T-Lymphocytes; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Thiazoles; Thiazolidines | 1991 |
Quantitative structure-activity relationships of antitumor guanidinothiazolecarboxamides with survival enhancement for therapy in the 3LL Lewis lung carcinoma model.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Female; Guanidines; Lung Neoplasms; Mice; Models, Biological; Neoplasms, Experimental; Structure-Activity Relationship; Thiazoles | 1991 |
Use of a colorimetric microtiter (MTT) assay in determining the radiosensitivity of cells from murine solid tumors.
Topics: Animals; Cell Survival; Colorimetry; Coloring Agents; Mice; Neoplasms, Experimental; Radiation Tolerance; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1988 |
Isothiazolopyrimidines--new group of anticancer agents. I.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Chemical Phenomena; Chemistry; Drug Screening Assays, Antitumor; Leukemia L1210; Lymphoma; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Pyrimidines; Sarcoma, Experimental; Thiazoles | 1987 |
A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity.
Topics: Animals; Cell Count; Cell Line; Cell Survival; Coloring Agents; Culture Media; Dimethyl Sulfoxide; Drug Evaluation, Preclinical; Formazans; Mice; Neoplasms, Experimental; Optics and Photonics; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors | 1987 |
Effect of sodium phenobarbital and sodium saccharin in AIN-76A diet on carcinogenesis initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and N,N-dibutylnitrosamine in male F344 rats.
Topics: Animals; Esophageal Neoplasms; FANFT; Hydrogen-Ion Concentration; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Rats; Rats, Inbred F344; Saccharin; Stomach Neoplasms; Thiazoles; Thyroid Neoplasms; Urinary Bladder Neoplasms | 1986 |
Carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl] acetamide in female rats.
Topics: Acetamides; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adenofibroma; Animals; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Chemical Phenomena; Chemistry; Female; Fibroma; Fibrosarcoma; Intestinal Neoplasms; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrofurans; Rats; Salivary Gland Neoplasms; Skin Neoplasms; Splenic Neoplasms; Thiazoles; Time Factors; Transplantation, Homologous | 1970 |
Carcinogenicity of formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]-hydrazide in Swiss mice.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Body Weight; Carcinogens; Carcinoma, Squamous Cell; Diet; Female; Formates; Hydrazines; Leukemia, Experimental; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Nitrofurans; Skin Neoplasms; Stomach Neoplasms; Thiazoles; Uterine Neoplasms | 1970 |
Studies on the anti-tumour activity of aliphatic aldehydes. 3. Formation of thiazoildine-4-carboxylic acid in tissues.
Topics: Aldehydes; Animals; Antineoplastic Agents; Butyrates; Carboxylic Acids; Carcinoma, Hepatocellular; Cysteine; Female; In Vitro Techniques; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Protein Biosynthesis; Rats; Thiazoles | 1971 |
Comparative urinary and gallbladder carcinogenicity of N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide and N-(4-(5-nitro-2-furyl)-2-thiazolyl)acetamide in the dog.
Topics: Acetamides; Adenocarcinoma; Adenocarcinoma, Scirrhous; Adenofibroma; Animals; Carcinogens; Carcinoma, Transitional Cell; Dogs; Female; Formamides; Gallbladder; Gallbladder Neoplasms; Kidney Neoplasms; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nitrofurans; Thiazoles; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Urogenital System | 1970 |
Levamisole inhibits and cures a solid malignant tumour and its pulmonary metastases in mice.
Topics: Animals; Antineoplastic Agents; Female; Imidazoles; Injections, Subcutaneous; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental; Stereoisomerism; Thiazoles; Time Factors | 1972 |
Demonstration of specific antigen in N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide induced rat bladder tumor.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Culture Techniques; Cytotoxicity Tests, Immunologic; Female; Formamides; Histocompatibility Antigens; Immunodiffusion; Isoenzymes; Karyotyping; L-Lactate Dehydrogenase; Neoplasm Transplantation; Neoplasms, Experimental; Nitrofurans; Parabiosis; Rats; Thiazoles; Urinary Bladder Neoplasms | 1973 |
Evaluation of urinary cytology as an indicator of bladder neoplasia in mice.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Erythrocytes; Female; Formamides; Hematuria; Mice; Neoplasms, Experimental; Nitrofurans; Thiazoles; Urinary Bladder Neoplasms; Urine | 1973 |
Comparative carcinogenicity in Swiss mice of N-(4-(5-nitro-2-furyl)-2-thiazolyl)acetamide and structurally related 5-nitrofurans and 4-nitrobenzenes.
Topics: Acetamides; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Formamides; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Neoplasms, Experimental; Nitrobenzenes; Nitrofurans; Papilloma; Stomach Neoplasms; Structure-Activity Relationship; Thiazoles; Thioacetamide; Urinary Bladder Neoplasms | 1973 |
Carcinostatic activity of a thiazolidinonylidene-hydrazonothiazolidinone derivative against DMBA-induced mammary carcinomata in female Sprague-Dawley rats.
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Breast Neoplasms; Carcinoma; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hydrazones; Neoplasms, Experimental; Rats; Thiazoles | 1973 |
Ultrastructure and reversibility of bladder carcinoma of rats produced by feeding of N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide.
Topics: Animals; Carcinogens; Carcinoma; Formamides; Hyperplasia; Male; Microscopy, Electron; Mitosis; Neoplasms, Experimental; Nitrofurans; Rats; Thiazoles; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1973 |
Carcinogenic activity of analogs of p-dimethylaminoazobenzene. VI. Activity of the benzimidazole and benzthiazole analogs.
Topics: Animals; Benzimidazoles; Carcinogens; Male; Methods; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Thiazoles | 1968 |
The use of N-(4-(5-nitro-2-furyl)-2-thiazolyl) formamide in the study of bladder cancer.
Topics: Amides; Animals; Carcinogens; Disease Models, Animal; Formamides; Neoplasms, Experimental; Nitrofurans; Rats; Solvents; Thiazoles; Urinary Bladder Neoplasms | 1972 |
Antitumor agents. Schiff bases from benzaldehyde nitrogen mustards and 2-phenyl-4-((3-amino-4-methoxy)phenyl)thiazole.
Topics: Animals; Antineoplastic Agents; Neoplasms, Experimental; Nitrogen Mustard Compounds; Schiff Bases; Thiazoles | 1971 |
[On the blastomogenic activity of phenanthrothiazoles].
Topics: Adenoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Lung Neoplasms; Male; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Papilloma; Sarcoma, Experimental; Sebaceous Gland Neoplasms; Skin Neoplasms; Thiazoles | 1969 |
Urinary bladder carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide in female Swiss mice.
Topics: Amides; Animals; Female; Leukemia, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Pregnancy; Thiazoles; Urinary Bladder Neoplasms; Uterine Neoplasms | 1970 |
Some sweetness left.
Topics: Academies and Institutes; Animals; Benzoates; Cyclamates; Foodborne Diseases; Lung Neoplasms; Mice; Neoplasms, Experimental; Rats; Saccharin; Sulfonamides; Sweetening Agents; Thiazoles; United States; Urinary Bladder Neoplasms | 1970 |
Induction, histogenesis, and isotransplanta bility of renal tumors induced by formic acid 2-[4-(5-nitro-2-furyl)-2-triazolyl]-hydrazide in rats.
Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Transitional Cell; Female; Formates; Hydrazines; Kidney Neoplasms; Male; Neoplasm Transplantation; Neoplasms, Experimental; Nitrofurans; Rats; Thiazoles; Transplantation, Homologous | 1970 |
Production of leukemia and stomach neoplasms in Swiss, RF, BALB-c, and C3H female mice by feeding N-[4-(5-nitro-2-furyl)-2-thiazolyl]acetamide.
Topics: Acetates; Adenoma; Amides; Animals; Anti-Bacterial Agents; Carcinogens; Carcinoma, Squamous Cell; Diet; Female; Leukemia, Experimental; Leukemia, Lymphoid; Lung Neoplasms; Mice; Neoplasms, Experimental; Nitrofurans; Species Specificity; Stomach Neoplasms; Thiazoles | 1970 |
Comparative carcinogenicity in the rat of 2-hydrazinothiazoles with nitrofuryl, nitrophenyl, or aminophenyl substituents in the 4-position.
Topics: Adenocarcinoma; Adenofibroma; Animals; Body Weight; Carcinogens; Chemical Phenomena; Chemistry; Diet; Female; Hydrazines; Lung Neoplasms; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Neoplasms, Experimental; Nitrobenzenes; Nitrofurans; Rats; Salivary Gland Neoplasms; Splenic Neoplasms; Thiazoles | 1970 |
Comparative carcinogenicity of formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide and related chemicals in the rat.
Topics: Animals; Carcinogens; Female; Formates; Furans; Hydrazines; Kidney Neoplasms; Liver Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Nitrofurans; Rats; Semicarbazides; Thiazoles | 1971 |
Effects of a synthetic antigonadotrophin (2-amino,5-nitrothiazole) on growth of experimental testicular teratomas.
Topics: Animals; Antimetabolites; Gonadotropins; Male; Neoplasms, Experimental; Poultry; Teratoma; Testicular Neoplasms; Thiazoles | 1966 |