thiazoles has been researched along with ER-Negative PR-Negative HER2-Negative Breast Cancer in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 18 (75.00) | 24.3611 |
| 2020's | 6 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheung, YM; Cromwell, GE; McDonnell, ME; Min, L; Tolaney, SM | 1 |
| Adalsteinsson, V; Batalini, F; Cantley, LC; D'Andrea, A; Eismann, J; Konstantinopoulos, PA; Matulonis, UA; Mayer, EL; Polak, M; Shapiro, GI; Swisher, EM; Tayob, N; Winer, EP; Wulf, GM; Xiong, N | 1 |
| Blackley, EF; Bujak, AZ; Callahan, J; Dawson, SJ; Francis, PA; Ftouni, S; Hicks, RJ; Ko, YA; Lee, CK; Lo, LL; Loi, S; Luen, SJ; Moodie, K; Savas, P; Silva, MJ; van Geelen, CT; Wein, L; Weng, CF; Yeung, MM | 1 |
| Chaudhry, AR; Denvir, J; Fan, J; Piwarski, SA; Primerano, DA; Salisbury, TB; Thompson, C | 1 |
| Irurzun-Arana, I; McDonald, TO; Michor, F; Trocóniz, IF | 1 |
| Bakacsy, L; Barta, A; Fazakas, C; Hohmann, J; Kele, Z; Krizbai, IA; Kúsz, N; Stefkó, D; Szepesi, Á; Vasas, A; Wilhelm, I | 1 |
| Bergmeier, SC; Burdick, MM; Champa, ZJ; Deosarkar, SP; Goetz, DJ; Lanier, OL; McCall, KD; Noori, MS; O'Brien, JD; Qi, C; Schwartz, FL | 1 |
| Chen, H; Du, Y; Li, Q; Ling, H; Qi, H; Shi, X; Song, L; Zhang, L; Zhang, Y | 1 |
| Bai, Y; Cheng, K; Sun, H; Wang, X; Yang, Z; Zhang, G; Zou, W | 1 |
| Boyle, K; Brantley, EJ; Campbell, PS; Daly, D; Mavingire, N; McLean, L; Rowland, LK; Thorne, G; Unternaehrer, J; Whang, S; Wooten, JV; Zylstra, D | 1 |
| Fu, J; Lin, Y; Liu, C; Lu, G; Lu, Z; Wan, X | 1 |
| Han, ES; Mortimer, J; Wen, W; Xing, Q; Yan, J; Yim, JH; Yost, SE; Yuan, Y | 1 |
| Guo, H; Hartkamp, J; Krämer, OH; Lüscher, B; Treude, F | 1 |
| Roux, PP; Shin, S; Tcherkezian, J; Vallabhapurapu, S; Wolgamott, L; Yoon, SO; Yu, Y | 1 |
| Boerner, J; Gartner, E; Kim, EM; Mueller, K | 1 |
| Baxter, RC; de Silva, HC; Lin, MZ; Martin, JL; Scott, CD | 1 |
| Cai, Y; Jiang, W; Peng, R; Shi, Y; Wu, G; Xia, Q | 1 |
| Abdissa, TT; Johnson, GL; Scott, JE; Tarpley, M | 1 |
| Blijlevens, M; Frangou, C; Guo, J; Li, YW; Nowak, NJ; Shen, H; Wilson, KE; Yang, N; Zhang, J | 1 |
| Feng, X; Liu, Q; Mai, B; Wang, P; Wang, X; Zhang, T | 1 |
| Chen, ZJ; Du, J; Liang, WT; Liu, H; Liu, HL; Liu, T; Lu, LL; Wang, HS; Wei, WD; Wu, YM; Yang, XL | 1 |
| Chen, ZJ; Du, J; Huang, HB; Jiang, GM; Liang, SW; Liu, Q; Wang, HS; Wu, YM; Zhang, KS; Zhou, Y | 1 |
| Chowdhury, N; Doddapaneni, R; Patel, K; Singh, M | 1 |
| Bansal, N; Bosch, A; Cubedo, E; Farias, E; Fishel, M; Jones, JW; Kane, M; Leibovitch, B; Pereira, L; Pierzchalski, K; Waxman, S; Yu, J; Zelent, A | 1 |
2 trial(s) available for thiazoles and ER-Negative PR-Negative HER2-Negative Breast Cancer
| Article | Year |
|---|---|
Phase 1b Clinical Trial with Alpelisib plus Olaparib for Patients with Advanced Triple-Negative Breast Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell-Free Nucleic Acids; Female; Humans; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Thiazoles; Triple Negative Breast Neoplasms | 2022 |
Alpelisib Monotherapy for PI3K-Altered, Pretreated Advanced Breast Cancer: A Phase II Study.
Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Mutation; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Thiazoles; Triple Negative Breast Neoplasms | 2022 |
22 other study(ies) available for thiazoles and ER-Negative PR-Negative HER2-Negative Breast Cancer
| Article | Year |
|---|---|
Factors leading to alpelisib discontinuation in patients with hormone receptor positive, human epidermal growth factor receptor-2 negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Middle Aged; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles; Triple Negative Breast Neoplasms | 2022 |
The putative endogenous AHR ligand ITE reduces JAG1 and associated NOTCH1 signaling in triple negative breast cancer cells.
Topics: Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Indoles; Jagged-1 Protein; Ligands; MCF-7 Cells; Receptor, Notch1; Receptors, Aryl Hydrocarbon; Signal Transduction; Thiazoles; Triple Negative Breast Neoplasms | 2020 |
Pharmacokinetic Profiles Determine Optimal Combination Treatment Schedules in Computational Models of Drug Resistance.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Death; Drug Administration Schedule; Drug Synergism; Erlotinib Hydrochloride; Female; Humans; Lung Neoplasms; Protein Kinase Inhibitors; Quinolines; Software; Thiazoles; Triple Negative Breast Neoplasms | 2020 |
Gerardiins A-L and Structurally Related Phenanthrenes from the Halophyte Plant
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Magnoliopsida; Mice; Molecular Structure; Phenanthrenes; Plant Extracts; Salt-Tolerant Plants; Tetrazolium Salts; Thiazoles; Triple Negative Breast Neoplasms | 2020 |
Phenylmethimazole and a thiazole derivative of phenylmethimazole inhibit IL-6 expression by triple negative breast cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Interleukin-8; Methimazole; NF-kappa B p50 Subunit; Thiazoles; Thiones; Transcription Factor RelA; Triple Negative Breast Neoplasms | 2017 |
The discovery of novel, potent ERR-alpha inverse agonists for the treatment of triple negative breast cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; ERRalpha Estrogen-Related Receptor; Female; Humans; Molecular Structure; Nitriles; Receptors, Estrogen; Structure-Activity Relationship; Thiazoles; Triple Negative Breast Neoplasms | 2017 |
PERK-Phosphorylated eIF2α Pathway Suppresses Tumor Metastasis Through Downregulating Expression of Programmed Death Ligand 1 and CXCL5 in Triple-Negative Breast Cancer.
Topics: Antineoplastic Agents; B7-H1 Antigen; Carboplatin; Chemokine CXCL5; Disease-Free Survival; Down-Regulation; Drug Resistance, Neoplasm; eIF-2 Kinase; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Indoles; Kaplan-Meier Estimate; MCF-7 Cells; Myeloid-Derived Suppressor Cells; Phosphorylation; Signal Transduction; T-Lymphocytes; Thiazoles; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2017 |
Putative tumor suppressor cytoglobin promotes aryl hydrocarbon receptor ligand-mediated triple negative breast cancer cell death.
Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Caspase 3; Cathepsin B; Cell Line, Tumor; Cytoglobin; Female; Humans; Ligands; Mice; Mice, Nude; Receptors, Aryl Hydrocarbon; Thiazoles; Transfection; Triple Negative Breast Neoplasms; Tumor Burden; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2019 |
pH sensitive peptide functionalized nanoparticles for co-delivery of erlotinib and DAPT to restrict the progress of triple negative breast cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Cell-Penetrating Peptides; Diamines; Drug Carriers; Drug Liberation; Erlotinib Hydrochloride; Female; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Oligopeptides; Receptors, Notch; Thiazoles; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2019 |
Combination therapy with BYL719 and LEE011 is synergistic and causes a greater suppression of p-S6 in triple negative breast cancer.
Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Drug Synergism; Enzyme Inhibitors; Female; Humans; Mice; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Purines; Retinoblastoma Protein; Ribosomal Protein S6 Kinases; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2019 |
PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1.
Topics: Caspase 8; DNA Damage; Drug Resistance, Neoplasm; Female; Humans; Inhibitor of Apoptosis Proteins; MCF-7 Cells; Neoplasm Proteins; Receptors, Thrombin; Signal Transduction; Thiazoles; Triple Negative Breast Neoplasms; Ubiquitin-Protein Ligases | 2019 |
Glycogen synthase kinase-3β positively regulates protein synthesis and cell proliferation through the regulation of translation initiation factor 4E-binding protein 1.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cell Growth Processes; Enzyme Inhibitors; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Nude; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Protein Binding; Protein Biosynthesis; Random Allocation; Thiazoles; Triple Negative Breast Neoplasms; Urea; Xenograft Model Antitumor Assays | 2014 |
Dasatinib is synergistic with cetuximab and cisplatin in triple-negative breast cancer cells.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Movement; Cetuximab; Cisplatin; Dasatinib; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Female; Humans; Neoplasm Invasiveness; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Triple Negative Breast Neoplasms | 2013 |
Inhibition of insulin-like growth factor-binding protein-3 signaling through sphingosine kinase-1 sensitizes triple-negative breast cancer cells to EGF receptor blockade.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 3; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Thiazoles; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2014 |
The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer cells to PARP inhibition.
Topics: BRCA1 Protein; CDC2 Protein Kinase; Cell Line, Tumor; DNA Damage; Female; Gene Expression Regulation, Neoplastic; Homologous Recombination; Humans; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolines; Thiazoles; Triple Negative Breast Neoplasms | 2014 |
Bosutinib reduces the efficacy of Dasatinib in triple-negative breast cancer cell lines.
Topics: Aniline Compounds; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dasatinib; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Nitriles; Protein Kinase Inhibitors; Pyrimidines; Quinolines; Thiazoles; Triple Negative Breast Neoplasms | 2014 |
Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Transformation, Neoplastic; Dasatinib; Flow Cytometry; Heterografts; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, SCID; Neoplastic Stem Cells; Protein Kinase Inhibitors; Pyrimidines; Signal Transduction; Thiazoles; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; Transcriptome; Transduction, Genetic; Transfection; Triple Negative Breast Neoplasms | 2014 |
Glycolytic inhibitors 2-deoxyglucose and 3-bromopyruvate synergize with photodynamic therapy respectively to inhibit cell migration.
Topics: Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Deoxyglucose; Drug Synergism; Fluorescent Antibody Technique; Glycolysis; Humans; Microscopy, Electron, Scanning; Photochemotherapy; Pyruvates; Tetrazolium Salts; Thiazoles; Triple Negative Breast Neoplasms | 2015 |
Inhibition of ERRα suppresses epithelial mesenchymal transition of triple negative breast cancer cells by directly targeting fibronectin.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Movement; Dose-Response Relationship, Drug; Drug Inverse Agonism; Epithelial-Mesenchymal Transition; ERRalpha Estrogen-Related Receptor; Female; Fibronectins; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Lung Neoplasms; MCF-7 Cells; Mice, Nude; Middle Aged; Nitriles; Promoter Regions, Genetic; Protein Binding; Receptors, Estrogen; Retrospective Studies; RNA Interference; Signal Transduction; Thiazoles; Time Factors; Transfection; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Inverse agonist of estrogen-related receptor α suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; ERRalpha Estrogen-Related Receptor; Female; Humans; Mice; Nitriles; Reactive Oxygen Species; Receptors, Estrogen; Signal Transduction; Thiazoles; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2016 |
Noscapine chemosensitization enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Coumarins; Docetaxel; Drug Carriers; Enzyme Activation; Fluorescent Antibody Technique; Humans; JNK Mitogen-Activated Protein Kinases; Liposomes; Mice; Microtubules; Nanoparticles; Noscapine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polymerization; Staining and Labeling; Taxoids; Thiazoles; Triple Negative Breast Neoplasms; Tubulin; Xenograft Model Antitumor Assays | 2016 |
Blocking the PAH2 domain of Sin3A inhibits tumorigenesis and confers retinoid sensitivity in triple negative breast cancer.
Topics: Animals; Antineoplastic Agents; Benzoates; Carcinogenesis; Cell Line, Tumor; Female; Humans; Indoles; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Receptors, Retinoic Acid; Repressor Proteins; Sin3 Histone Deacetylase and Corepressor Complex; Tetrahydronaphthalenes; Thiazoles; Triple Negative Breast Neoplasms | 2016 |