Page last updated: 2024-08-21

thiazoles and Down Syndrome

thiazoles has been researched along with Down Syndrome in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (15.79)	18.2507
2000's	5 (26.32)	29.6817
2010's	10 (52.63)	24.3611
2020's	1 (5.26)	2.80

Authors

Authors	Studies
Barone, E; Di Domenico, F; Francioso, A; Lanzillotta, C; Pagnotta, S; Perluigi, M; Tramutola, A; Zuliani, I	1
Beckett, TL; Cauvi, FM; Doran, E; Head, E; LeVine, H; Lott, IT; Matveev, S; McCarty, K; Murphy, MP; Schmitt, F; Spielmann, HP	1
Bulova, P; Christian, BT; Devenny, D; Handen, BL; Hardison, R; Hartley, SL; Johnson, SC; Klunk, WE; Lao, PJ; Mihaila, I	1
Aizenstein, HJ; Anderson, SJ; Christian, BT; Cohen, AD; Comer, D; Handen, BL; Hartley, S; Johnson, S; Klunk, WE; Lao, P; Laymon, CM; Lopresti, BJ; Mathis, CA; Minhas, DS; Price, JC; Snitz, BE; Tudorascu, DL; Yu, Z	1
Annus, T; Fryer, TD; Holland, AJ; Hong, YT; Nestor, PJ; Vatansever, D; Williams, GB; Wilson, LR; Zaman, SH	1
Christian, BT; Cohen, AD; Devenny, DA; Handen, BL; Hardison, R; Hartley, SL; Johnson, SC; Klunk, WE; Mailick, MR; Mihaila, I; Price, JC	1
Chen, J; LeVine, H; Matveev, SV; Metts, BM; Onono, F; Scheff, SW; Spielmann, HP; Walker, LC; Zhu, H	1
Barnhart, TE; Betthauser, TJ; Bulova, PD; Christian, BT; Cohen, AD; Devenny, DA; Handen, BL; Hardison, R; Hartley, SL; Higgins, AT; Hillmer, AT; Johnson, SC; Klunk, WE; Lao, PJ; Mailick, MR; Mathis, CA; Mihaila, I; Murali, D; Price, JC; Tumuluru, RV	1
Acosta-Cabronero, J; Annus, T; Cardenas-Blanco, A; Coles, JP; Fryer, TD; Holland, AJ; Hong, YT; Menon, DK; Nestor, PJ; Wilson, LR; Zaman, SH	1
Aigbirhio, FI; Baron, JC; Canales, R; D'Abrera, JC; Fryer, TD; Holland, AJ; Hong, YT; Landt, J; Menon, DK; Zaman, SH	1
Bulova, P; Cannon, SA; Channamalappa, U; Cohen, AD; Cohen, WI; Handen, BL; Klunk, WE; Mathis, CA; Price, JC	1
Bellmann, C; Giasson, BI; Horiguchi, T; Ischiropoulos, H; Lee, VM; LightFoot, R; Richter-Landsberg, C; Trojanowski, JQ; Uryu, K	1
Fonseca, MI; Kawas, CH; Tenner, AJ; Troncoso, JC	1
Duff, K; Hashimoto, T; Iwatsubo, T; Kowa, H; Mann, DM; Matsuura, Y; Sakakura, T; Tsuji, S; Wakabayashi, T	1
Cotman, CW; Cummings, BJ; Su, JH	1
Beavis, RC; Frangione, B; Golabek, A; Lalowski, M; Lemere, CA; Selkoe, DJ; Wisniewski, HM; Wisniewski, T	1
Di Mauro, M; Grillo, C; La Mantia, I; Mattina, T; Meroni, PL; Nicoletti, F; Xiang, M; Zaccone, P	1
Azizeh, BY; Cotman, CW; Cribbs, DH; Head, E; Lott, IT; Tenner, AJ	1
Gur, TL; Hou, C; Kung, HF; Kung, MP; Lee, VM; Plössl, K; Skovronsky, DM; Trojanowski, JQ; Zhuang, ZP	1

Trials

1 trial(s) available for thiazoles and Down Syndrome

Article	Year
Prophylaxis with the novel immunomodulator pidotimod reduces the frequency and severity of upper respiratory tract infections in children with Down's syndrome. Journal of chemotherapy (Florence, Italy), 1999, Volume: 11, Issue:2 Topics: Adolescent; Child; Child, Preschool; Down Syndrome; Female; Humans; Immunologic Factors; Incidence; Male; Pyrrolidonecarboxylic Acid; Recurrence; Respiratory Tract Infections; Severity of Illness Index; Thiazoles; Thiazolidines	1999

Article

Year

Prophylaxis with the novel immunomodulator pidotimod reduces the frequency and severity of upper respiratory tract infections in children with Down's syndrome.

Journal of chemotherapy (Florence, Italy), 1999, Volume: 11, Issue:2

Topics: Adolescent; Child; Child, Preschool; Down Syndrome; Female; Humans; Immunologic Factors; Incidence; Male; Pyrrolidonecarboxylic Acid; Recurrence; Respiratory Tract Infections; Severity of Illness Index; Thiazoles; Thiazolidines

1999

Other Studies

18 other study(ies) available for thiazoles and Down Syndrome

Article	Year
The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:1 Topics: Amyloid beta-Protein Precursor; Animals; beta-N-Acetylhexosaminidases; Blotting, Western; Brain; Disease Models, Animal; Down Syndrome; Female; Fluorescent Antibody Technique; Immunoprecipitation; Male; Mice; N-Acetylglucosaminyltransferases; Pyrans; Real-Time Polymerase Chain Reaction; tau Proteins; Thiazoles	2021
Down syndrome: age-dependence of PiB binding in postmortem frontal cortex across the lifespan. Neurobiology of aging, 2017, Volume: 54 Topics: Adolescent; Adult; Aged; Aging; Amyloid beta-Peptides; Aniline Compounds; Autopsy; Cerebral Amyloid Angiopathy; Child; Child, Preschool; Cognition; Down Syndrome; Female; Frontal Lobe; Humans; Infant; Ligands; Male; Middle Aged; Positron-Emission Tomography; Protein Binding; Thiazoles; Young Adult	2017
Cognitive decline and brain amyloid-β accumulation across 3 years in adults with Down syndrome. Neurobiology of aging, 2017, Volume: 58 Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognition; Cognitive Dysfunction; Down Syndrome; Executive Function; Female; Humans; Male; Memory, Episodic; Middle Aged; Phenanthrolines; Positron-Emission Tomography; Thiazoles; Time Factors	2017
Comparison of longitudinal Aβ in nondemented elderly and Down syndrome. Neurobiology of aging, 2019, Volume: 73 Topics: Adult; Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Cohort Studies; Down Syndrome; Female; Frontal Lobe; Heterozygote; Humans; Longitudinal Studies; Male; Middle Aged; Parietal Lobe; Thiazoles; Time Factors; Ventral Striatum	2019
Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity. Human brain mapping, 2019, 10-15, Volume: 40, Issue:15 Topics: Adult; Alzheimer Disease; Amyloid; Aniline Compounds; Carbon Radioisotopes; Cerebral Cortex; Connectome; Cross-Sectional Studies; Down Syndrome; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles	2019
Cognitive functioning in relation to brain amyloid-β in healthy adults with Down syndrome. Brain : a journal of neurology, 2014, Volume: 137, Issue:Pt 9 Topics: Adult; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognition Disorders; Down Syndrome; Female; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neocortex; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles	2014
A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brain. Journal of neurochemistry, 2014, Volume: 131, Issue:3 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Binding Sites; Brain Chemistry; Down Syndrome; Female; Frontal Lobe; Humans; In Vitro Techniques; Lipid Metabolism; Male; Proteomics; Thiazoles	2014
The effects of normal aging on amyloid-β deposition in nondemented adults with Down syndrome as imaged by carbon 11-labeled Pittsburgh compound B. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2016, Volume: 12, Issue:4 Topics: Adult; Aging; Aniline Compounds; Apolipoproteins E; Brain; Carbon Radioisotopes; Cohort Studies; Down Syndrome; Female; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles	2016
The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis. Neurobiology of aging, 2017, Volume: 53 Topics: Adult; Aged; Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Aniline Compounds; Brain Diseases, Metabolic; Cerebral Cortex; Cross-Sectional Studies; Down Syndrome; Female; Gray Matter; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Thiazoles	2017
Using positron emission tomography and Carbon 11-labeled Pittsburgh Compound B to image Brain Fibrillar β-amyloid in adults with down syndrome: safety, acceptability, and feasibility. Archives of neurology, 2011, Volume: 68, Issue:7 Topics: Adult; Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Benzothiazoles; Brain; Brain Mapping; Down Syndrome; Female; Humans; Male; Middle Aged; Positron-Emission Tomography; Thiazoles; Young Adult	2011
Imaging brain amyloid in nondemented young adults with Down syndrome using Pittsburgh compound B. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2012, Volume: 8, Issue:6 Topics: Adult; Amyloidogenic Proteins; Aniline Compounds; Brain; Down Syndrome; Female; Humans; Male; Neuroimaging; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles; Young Adult	2012
Nitration of tau protein is linked to neurodegeneration in tauopathies. The American journal of pathology, 2003, Volume: 163, Issue:3 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Ganglia; Benzothiazoles; Cell Line; Cerebral Cortex; Down Syndrome; Female; Fluorescent Dyes; Humans; Male; Middle Aged; Nerve Degeneration; Neurodegenerative Diseases; Neurofibrillary Tangles; Nitrates; Pick Disease of the Brain; tau Proteins; Tauopathies; Thiazoles; Tissue Distribution	2003
Neuronal localization of C1q in preclinical Alzheimer's disease. Neurobiology of disease, 2004, Volume: 15, Issue:1 Topics: Adult; Aged; Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Biomarkers; Brain; Cerebral Cortex; Complement C1q; Disease Progression; Down Syndrome; Encephalitis; Female; Genetic Predisposition to Disease; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Humans; Immunohistochemistry; Middle Aged; Neurons; Peptide Fragments; Plaque, Amyloid; Thiazoles	2004
Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits. The American journal of pathology, 2004, Volume: 165, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Benzothiazoles; Down Syndrome; Female; Fluorescent Antibody Technique, Indirect; Humans; Immunohistochemistry; Male; Membrane Proteins; Mice; Mice, Transgenic; Middle Aged; Neocortex; Neurons; Non-Fibrillar Collagens; Peptide Fragments; Plaque, Amyloid; Thiazoles; Tissue Distribution	2004
Neuritic involvement within bFGF immunopositive plaques of Alzheimer's disease. Experimental neurology, 1993, Volume: 124, Issue:2 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal; Benzothiazoles; Biomarkers; Child; Child, Preschool; Down Syndrome; Fibroblast Growth Factor 2; Fluorescent Dyes; Heparitin Sulfate; Humans; Immunohistochemistry; Middle Aged; Nerve Fibers; Neurites; Neurofibrillary Tangles; Thiazoles	1993
The "nonamyloidogenic" p3 fragment (amyloid beta17-42) is a major constituent of Down's syndrome cerebellar preamyloid. The Journal of biological chemistry, 1996, Dec-27, Volume: 271, Issue:52 Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Brain; Chromatography, High Pressure Liquid; Down Syndrome; Electrophoresis, Polyacrylamide Gel; Fluorometry; Humans; Mass Spectrometry; Thiazoles	1996
Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome. Neurobiology of disease, 2001, Volume: 8, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Brain; Complement C1q; Down Syndrome; Encephalitis; Female; Humans; Immunohistochemistry; Male; Microglia; Middle Aged; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; Thiazoles	2001
Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autoradiography; Benzene Derivatives; Blood-Brain Barrier; Brain; Down Syndrome; Humans; Indicators and Reagents; Iodine Radioisotopes; Isotope Labeling; Kinetics; Ligands; Mice; Peptide Fragments; Structure-Activity Relationship; Styrenes; Thiazoles; Tissue Distribution	2001