Compounds > thiazoles
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thiazoles and Diabetic Retinopathy

thiazoles has been researched along with Diabetic Retinopathy in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's3 (18.75)18.2507
2000's5 (31.25)29.6817
2010's5 (31.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Chen, N; Huang, N; Jiang, Q; Li, Y; Luo, WF; Yao, J1
Howell, SJ; Lee, CA; Lindstrom, SI; Tang, J; Taylor, BE; Taylor, PR; Taylor, ZRR; Zapadka, TE1
Imai, K; Inoue, T; Miyake, H; Morita, M; Moritomo, A; Nagashima, A; Tojo, T1
Inoue, T; Miyake, H; Morita, M; Moritomo, A; Nagashima, A; Tojo, T1
Yu, J; Zhang, J; Zhao, H1
Im, JE; Jeong, JH; Kim, JT; Kim, JY; Kim, SR; Park, SG; Suh, W; Sung, JH; Woo, SJ1
Hu, LM; Lei, X; Li, W; Mou, L; Shen, J; Wu, Y; Xu, G; Xu, GT; Zhang, J1
Aso, Y; Inukai, T; Takanashi, K; Takemura, Y; Tayama, K1
Kawakami, M; Kuroki, M1
Hosotani, H; Ohashi, Y; Tsubota, K; Yamada, M1
Ishikawa, H; Kobayashi, F; Matsui, T; Matsuura, A; Nakamura, Y1
Akira, T; Naka, H1
Fresneau, P1
Adamis, AP; Döhmen, S; Joussen, AM; Kirchhof, B; Koizumi, K; Mitsiades, N; Poulaki, V1
Jo, I; Kim, HT; Kim, J; Kim, KS; Oh, YS; Shinn, JW; Shinn, SH1
Harada, T; Hotta, N; Kakuta, H; Kojima, K; Matsubara, H; Mizuno, K; Sakamoto, N; Suzuki, M1

Reviews

3 review(s) available for thiazoles and Diabetic Retinopathy

ArticleYear
[Aminoguanidine and other AGE inhibitors].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9

    Topics: Amides; Animals; Arteriosclerosis; Cardiovascular Diseases; Cataract; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Retinopathy; Disease Models, Animal; Drug Design; Glycation End Products, Advanced; Guanidines; Humans; Hydrazines; Hypoglycemic Agents; Thiadiazoles; Thiazoles; Thiazolidines

2002
[SG-210].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl

    Topics: Aldehyde Reductase; Animals; Benzothiazoles; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Erythrocytes; Humans; Hypoglycemic Agents; Sorbitol; Thiazines; Thiazoles

1997
[Imidazolidine/thiazolidine-acetate aldose reductase inhibitors].
    Annales pharmaceutiques francaises, 2000, Volume: 58, Issue:6

    Topics: Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Drug Design; Enzyme Inhibitors; Humans; Imidazoles; Structure-Activity Relationship; Thiazoles

2000

Trials

2 trial(s) available for thiazoles and Diabetic Retinopathy

ArticleYear
High glucose concentrations abolish the superoxide dismutase response of leukocytes to ascorbic acid or troglitazone in type 2 diabetes mellitus.
    Life sciences, 2002, Apr-05, Volume: 70, Issue:20

    Topics: Aged; Albuminuria; Antioxidants; Ascorbic Acid; Chromans; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Female; Glucose; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Leukocytes; Male; Middle Aged; Superoxide Dismutase; Thiazoles; Thiazolidinediones; Troglitazone

2002
Reversal of abnormal corneal epithelial cell morphologic characteristics and reduced corneal sensitivity in diabetic patients by aldose reductase inhibitor, CT-112.
    American journal of ophthalmology, 1995, Volume: 119, Issue:3

    Topics: Aged; Aldehyde Reductase; Cornea; Corneal Diseases; Diabetes Complications; Diabetic Retinopathy; Epithelium; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Sensation; Thiazoles; Thiazolidinediones

1995

Other Studies

11 other study(ies) available for thiazoles and Diabetic Retinopathy

ArticleYear
The Nrf2 activator MIND4-17 protects retinal ganglion cells from high glucose-induced oxidative injury.
    Journal of cellular physiology, 2020, Volume: 235, Issue:10

    Topics: Animals; Cells, Cultured; CRISPR-Cas Systems; Diabetic Retinopathy; Gene Knockout Techniques; Glucose; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Oxidative Stress; Retinal Ganglion Cells; Signal Transduction; Thiazoles

2020
RORγt Inhibitor-SR1001 Halts Retinal Inflammation, Capillary Degeneration, and the Progression of Diabetic Retinopathy.
    International journal of molecular sciences, 2020, May-17, Volume: 21, Issue:10

    Topics: Animals; Capillaries; Cell Death; Cell Survival; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Drug Inverse Agonism; Endothelial Cells; Hyperglycemia; Inflammation; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Receptor Subfamily 1, Group F, Member 3; Oxidative Stress; Retinal Vessels; Sulfonamides; Thiazoles

2020
Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema: part 2.
    Bioorganic & medicinal chemistry, 2013, May-01, Volume: 21, Issue:9

    Topics: Amine Oxidase (Copper-Containing); Animals; Cell Adhesion Molecules; Diabetic Retinopathy; Dose-Response Relationship, Drug; Humans; Macular Edema; Models, Molecular; Molecular Structure; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazoles

2013
Novel 1H-imidazol-2-amine derivatives as potent and orally active vascular adhesion protein-1 (VAP-1) inhibitors for diabetic macular edema treatment.
    Bioorganic & medicinal chemistry, 2013, Jul-01, Volume: 21, Issue:13

    Topics: Amine Oxidase (Copper-Containing); Amines; Animals; Cell Adhesion Molecules; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Humans; Macular Edema; Male; Models, Molecular; Molecular Docking Simulation; Rats; Rats, Sprague-Dawley; Thiazoles

2013
HMGB-1 as a Potential Target for the Treatment of Diabetic Retinopathy.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Oct-11, Volume: 21

    Topics: Blood Glucose; Cell Line; Cell Survival; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; HMGB1 Protein; Humans; Inflammation; NF-kappa B p50 Subunit; Peripheral Nervous System Diseases; Real-Time Polymerase Chain Reaction; Retinal Ganglion Cells; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Toll-Like Receptor 4; Transfection; Up-Regulation

2015
The cKit Inhibitor, Masitinib, Prevents Diabetes-Induced Retinal Vascular Leakage.
    Investigative ophthalmology & visual science, 2016, Volume: 57, Issue:3

    Topics: Animals; Benzamides; Blood-Retinal Barrier; Blotting, Western; Capillary Permeability; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelium, Vascular; Gene Expression Regulation; Humans; Immunohistochemistry; Intravitreal Injections; Male; Mice; Mice, Inbred C57BL; Piperidines; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Retinal Diseases; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Stem Cell Factor; Thiazoles; Vascular Resistance

2016
EPO attenuates inflammatory cytokines by Muller cells in diabetic retinopathy.
    Frontiers in bioscience (Elite edition), 2011, 01-01, Volume: 3, Issue:1

    Topics: Animals; Cell Line; Cytokines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Gene Expression Regulation; In Situ Nick-End Labeling; Interleukin-1beta; Interleukin-6; Luciferases; NF-kappa B; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2011
Pharmacological profiles of a novel aldose reductase inhibitor, SPR-210, and its effects on streptozotocin-induced diabetic rats.
    Japanese journal of pharmacology, 1994, Volume: 64, Issue:2

    Topics: Aldehyde Reductase; Animals; Benzothiazoles; Cattle; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diabetic Retinopathy; Electroretinography; Erythrocytes; Humans; Kinetics; Male; Motor Neurons; Neural Conduction; Rats; Rats, Sprague-Dawley; Sorbitol; Swine; Thiazines; Thiazoles

1994
Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood-Retinal Barrier; Cell Adhesion; Cyclooxygenase Inhibitors; Diabetic Retinopathy; Etanercept; Immunoglobulin G; Intercellular Adhesion Molecule-1; Kinetics; Meloxicam; Models, Biological; Neutrophils; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Long-Evans; Receptors, Leukocyte-Adhesion; Receptors, Tumor Necrosis Factor; Retina; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha

2002
The effect of antioxidants on glycated albumin-induced cytotoxicity in bovine retinal pericytes.
    Biochemical and biophysical research communications, 2002, Apr-12, Volume: 292, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Cell Death; Cell Survival; Cells, Cultured; Chromans; Cytoprotection; Diabetic Retinopathy; Dose-Response Relationship, Drug; Glycated Serum Albumin; Glycation End Products, Advanced; Mitochondria; Oxidative Stress; Pericytes; Probucol; Retina; Retinal Vessels; Serum Albumin; Tetrazolium Salts; Thiazoles; Time Factors

2002
[Experimentally induced diabetic retinal microangiopathy and polyol pathway. II. Effect of aldose reductase inhibitors on microangiopathy].
    Nippon Ganka Gakkai zasshi, 1985, Volume: 89, Issue:2

    Topics: Aldehyde Reductase; Animals; Diabetic Retinopathy; Male; Rats; Rats, Inbred Strains; Rhodanine; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines

1985