Page last updated: 2024-08-21

thiazoles and Dementias, Transmissible

thiazoles has been researched along with Dementias, Transmissible in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (3.70)	18.2507
2000's	10 (37.04)	29.6817
2010's	16 (59.26)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Anson, KJ; Campbell, KJ; Caughey, B; Groveman, BR; Hughson, AG; Kraus, A; Manca, M; Orrù, CD; Raymond, GJ; Raymond, LD	1
Abskharon, R; Castilla, J; Dang, J; Elfarash, A; Fujioka, H; Hassan, S; Mulaj, M; Shen, P; Steyaert, J; Surewicz, WK; Wang, F; Wang, Z; Wohlkonig, A; Zou, LS; Zou, WQ	1
Doh-Ura, K; Kitamoto, T; Nishizawa, K; Oguma, A; Sakasegawa, Y; Teruya, K	1
Benet, LZ; Dalvie, DK; Elepano, M; Fife, KL; Freyman, Y; Gallardo-Godoy, A; Gever, JR; Giles, K; Huang, Y; Jacobson, MP; Li, Z; Prusiner, SB; Rao, S; Renslo, AR; Silber, BM	1
Bryant, C; Dolghih, E; Elepano, M; Gallardo-Godoy, A; Gever, JR; Jacobson, MP; Li, Z; Prusiner, SB; Rao, S; Renslo, AR; Silber, BM; Widjaja, K	1
Bannach, O; Birkmann, E; Luers, L; Nagel-Steger, L; Riesner, D; Stöhr, J; Willbold, D; Wolff, M; Wördehoff, MM	1
Doh-ura, K; Teruya, K	1
Ghaemmaghami, S; Renslo, AR; Russo, M	1
Chen, J; Liang, Y; Pan, K; Yi, CW	1
Collins, SJ; Haigh, CL	1
Giles, K; Olson, SH; Prusiner, SB	1
Bawumia, S; Bayley, PM; Bronstein, I; Dear, D; Dodson, G; Hirst, E; Martin, S; Nash, A; Polyakova, O; Stern, I	1
Arai, H; Doh-ura, K; Furukawa, K; Furumoto, S; Itoyama, Y; Iwata, R; Kudo, Y; Okamura, N; Shiga, Y; Tashiro, M; Tsuboi, Y; Yanai, K	1
Ghaemmaghami, S; May, BC; Prusiner, SB; Renslo, AR	1
Fife, KL; Gallardo-Godoy, A; Gever, J; Prusiner, SB; Renslo, AR; Silber, BM	1
Artamonova, TO; Artemov, AV; Khodorkovskiĭ, MA; Mikhaĭlova, EV; Nevzgliadova, OV; Snigirevskaia, ES; Soĭdla, TR	1
Cortez, LM; Kumar, J; Renault, L; Sim, VL; Young, HS	1
Carcassola, G; Ceciliani, F; Colombo, L; Dall'Ara, P; Gervasoni, M; Giannino, ML; Martino, PA; Poli, G; Pollera, C; Ponti, W; Salmona, M; Villa, S	1
Surewicz, KA; Surewicz, WK; Vanik, DL	1
Doh-ura, K	1
Bryszewska, M; Cladera, J; Cortijo-Arellano, M; Klajnert, B	1
Jones, EM; Surewicz, K; Surewicz, WK	1
Caughey, B; James, W; Sim, VL; Tahiri-Alaoui, A	1
Doh-ura, K; Ishikawa, K; Iwaki, T; Kudo, Y; Nishida, N; Sawada, T; Suemoto, T	1
Chen, B; Cope, H; Heal, W; Louth, JC; Mutter, R; Thompson, MJ	1
Nandi, PK	1
Bose, S; Gu, Y; Kalepu, S; Mishra, RS; Singh, N; Verghese, S	1

Reviews

4 review(s) available for thiazoles and Dementias, Transmissible

Article	Year
Amyloid-binding compounds and their anti-prion potency. Current topics in medicinal chemistry, 2013, Volume: 13, Issue:19 Topics: Amyloid; Animals; Benzoxazoles; Humans; Molecular Structure; Phenylhydrazines; Prion Diseases; Prions; Thiazoles	2013
Successes and challenges in phenotype-based lead discovery for prion diseases. Journal of medicinal chemistry, 2014, Aug-28, Volume: 57, Issue:16 Topics: Animals; Brain; Creutzfeldt-Jakob Syndrome; Disease Models, Animal; Drug Discovery; Drug Evaluation, Preclinical; Humans; Mice; Prion Diseases; Structure-Activity Relationship; Thiazoles	2014
Developing Therapeutics for PrP Prion Diseases. Cold Spring Harbor perspectives in medicine, 2017, Apr-03, Volume: 7, Issue:4 Topics: Animals; Disease Progression; High-Throughput Screening Assays; Humans; Mice; Molecular Targeted Therapy; Polyelectrolytes; Polymers; Prion Diseases; Prions; Protein Conformation; Thiazoles	2017
[Therapeutics for prion diseases]. Rinsho shinkeigaku = Clinical neurology, 2003, Volume: 43, Issue:11 Topics: Amyloid; Animals; Benzothiazoles; Clinical Trials as Topic; Drug Design; Humans; Pentosan Sulfuric Polyester; Prion Diseases; Prions; Protein Binding; Quinacrine; Thiazoles	2003

Trials

1 trial(s) available for thiazoles and Dementias, Transmissible

Article	Year
In vivo detection of prion amyloid plaques using [(11)C]BF-227 PET. European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Autoradiography; Benzoxazoles; Brain; Carbon Radioisotopes; Case-Control Studies; Female; Humans; Male; Middle Aged; Plaque, Amyloid; Positron-Emission Tomography; Prion Diseases; Prions; Thiazoles	2010

Other Studies

22 other study(ies) available for thiazoles and Dementias, Transmissible

Article	Year
RT-QuIC Assays for Prion Disease Detection and Diagnostics. Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1658 Topics: Amyloid; Animals; Benzothiazoles; Biological Assay; Brain; Brain Chemistry; Fluorescent Dyes; Gene Expression; Humans; Nasal Cavity; Prion Diseases; Protein Conformation, beta-Strand; Protein Folding; PrPC Proteins; PrPSc Proteins; Recombinant Proteins; Sensitivity and Specificity; Thiazoles	2017
Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors. Microbial cell factories, 2017, Oct-04, Volume: 16, Issue:1 Topics: Animals; Arvicolinae; Benzothiazoles; Circular Dichroism; Escherichia coli; Humans; Mice; Mice, Transgenic; Microscopy, Electron; Oxidoreductases; Polymorphism, Genetic; Prion Diseases; Prion Proteins; Prions; Protein Aggregates; PrPC Proteins; Surface Plasmon Resonance; Thiazoles	2017
Intermolecular crosslinking of abnormal prion protein is efficiently induced by a primuline-sensitized photoreaction. Biochimica et biophysica acta. General subjects, 2019, Volume: 1863, Issue:2 Topics: Animals; Antibodies; Brain; Cell Line, Tumor; Dose-Response Relationship, Drug; Mice; Mice, Inbred ICR; Photosensitizing Agents; Prion Diseases; Prion Proteins; Thiazoles; Time Factors; Ultraviolet Rays	2019
Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice. Pharmaceutical research, 2013, Volume: 30, Issue:4 Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Brain; Cell Line; Cytochrome P-450 Enzyme System; Humans; Mice; Microsomes, Liver; Prion Diseases; Protein Isoforms; PrPSc Proteins; Solubility; Thiazoles	2013
2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease. ChemMedChem, 2013, Volume: 8, Issue:5 Topics: Administration, Oral; Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Mice; Models, Molecular; Molecular Structure; Pregnancy Proteins; Prion Diseases; Quantum Theory; Structure-Activity Relationship; Thiazoles	2013
Seeded fibrillation as molecular basis of the species barrier in human prion diseases. PloS one, 2013, Volume: 8, Issue:8 Topics: Amyloid; Animals; Benzothiazoles; Cattle; Circular Dichroism; Deer; Humans; Kinetics; Prion Diseases; PrPSc Proteins; Sheep; Species Specificity; Thiazoles; Ultracentrifugation	2013
Zinc significantly changes the aggregation pathway and the conformation of aggregates of human prion protein. Biochimica et biophysica acta, 2015, Volume: 1854, Issue:8 Topics: Benzothiazoles; Humans; Prion Diseases; Prions; Protein Aggregates; Protein Conformation; Thiazoles; Zinc	2015
Simplified Murine 3D Neuronal Cultures for Investigating Neuronal Activity and Neurodegeneration. Cell biochemistry and biophysics, 2017, Volume: 75, Issue:1 Topics: Animals; Benzothiazoles; Calcium Signaling; Cell Culture Techniques; Cell Differentiation; Cell Survival; Cells, Cultured; Mice; Microscopy, Confocal; Models, Neurological; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Prion Diseases; Spheroids, Cellular; Thiazoles	2017
Proteolysis of prion protein by cathepsin S generates a soluble beta-structured intermediate oligomeric form, with potential implications for neurotoxic mechanisms. European biophysics journal : EBJ, 2009, Volume: 38, Issue:2 Topics: Animals; Benzothiazoles; Cathepsins; Circular Dichroism; Hydrolysis; Neurotoxins; Peptide Fragments; Prion Diseases; Prions; Protein Conformation; Protein Folding; Protein Multimerization; Sequence Deletion; Sheep; Thiazoles	2009
Discovery of 2-aminothiazoles as potent antiprion compounds. Journal of virology, 2010, Volume: 84, Issue:7 Topics: Animals; Cell Line, Tumor; Drug Discovery; Enzyme-Linked Immunosorbent Assay; High-Throughput Screening Assays; Mice; Prion Diseases; Prions; PrPSc Proteins; Structure-Activity Relationship; Thiazoles	2010
2-Aminothiazoles as therapeutic leads for prion diseases. Journal of medicinal chemistry, 2011, Feb-24, Volume: 54, Issue:4 Topics: Animals; Biological Assay; Brain; Cell Line, Tumor; Cell Survival; Magnetic Resonance Spectroscopy; Mice; Prion Diseases; PrPSc Proteins; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Thiazoles	2011
[The effect of red pigment of Saccharomyces cerevisiae on insulin fibril formation in vitro]. Tsitologiia, 2011, Volume: 53, Issue:10 Topics: Amyloid; Animals; Benzothiazoles; Biomimetic Materials; Fluorescence; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Hydrolysis; Insulin; Microscopy, Electron; Microscopy, Electron, Transmission; Pigments, Biological; Prion Diseases; Saccharomyces cerevisiae; Solutions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles	2011
Mouse prion protein polymorphism Phe-108/Val-189 affects the kinetics of fibril formation and the response to seeding: evidence for a two-step nucleation polymerization mechanism. The Journal of biological chemistry, 2013, Feb-15, Volume: 288, Issue:7 Topics: Alleles; Animals; Benzothiazoles; Circular Dichroism; Dose-Response Relationship, Drug; Kinetics; Mice; Microscopy, Electron; Phenylalanine; Polymers; Polymorphism, Genetic; Prion Diseases; Prions; Protein Conformation; Recombinant Proteins; Thiazoles; Time Factors; Valine	2013
In vitro evaluation of the anti-prionic activity of newly synthesized congo red derivatives. Arzneimittel-Forschung, 2003, Volume: 53, Issue:12 Topics: Amino Acid Sequence; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Congo Red; Cricetinae; Endopeptidases; Flow Cytometry; Fluorescent Antibody Technique; Mesocricetus; Mice; Microscopy, Electron; Molecular Sequence Data; Neuroblastoma; Peptide Fragments; Prion Diseases; Prions; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	2003
Molecular basis of barriers for interspecies transmissibility of mammalian prions. Molecular cell, 2004, Apr-09, Volume: 14, Issue:1 Topics: Amino Acid Sequence; Amino Acid Substitution; Amyloid; Animals; Animals, Genetically Modified; Benzothiazoles; Cattle; Disease Transmission, Infectious; Fluorescent Dyes; Humans; Molecular Sequence Data; Prion Diseases; Prions; Protein Conformation; Recombinant Proteins; Sequence Alignment; Species Specificity; Thiazoles	2004
Influence of heparin and dendrimers on the aggregation of two amyloid peptides related to Alzheimer's and prion diseases. Biochemical and biophysical research communications, 2006, Jan-13, Volume: 339, Issue:2 Topics: Alzheimer Disease; Amyloid; Benzothiazoles; Dendrimers; Heparin; Kinetics; Molecular Structure; Peptide Fragments; Prion Diseases; Spectrometry, Fluorescence; Thiazoles	2006
Role of N-terminal familial mutations in prion protein fibrillization and prion amyloid propagation in vitro. The Journal of biological chemistry, 2006, Mar-24, Volume: 281, Issue:12 Topics: Amyloid; Benzothiazoles; Escherichia coli; Genetic Predisposition to Disease; Humans; In Vitro Techniques; Kinetics; Methionine; Microscopy, Atomic Force; Molecular Conformation; Mutation; Plasmids; Polymorphism, Genetic; Prion Diseases; Prions; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Spectroscopy, Fourier Transform Infrared; Thiazoles; Time Factors; Valine	2006
Molecular heterosis of prion protein beta-oligomers. A potential mechanism of human resistance to disease. The Journal of biological chemistry, 2006, Nov-10, Volume: 281, Issue:45 Topics: Alleles; Amyloid; Benzothiazoles; Circular Dichroism; Heterozygote; Homozygote; Humans; Hybrid Vigor; Kinetics; Methionine; Prion Diseases; Prions; Thiazoles; Valine	2006
Styrylbenzoazole derivatives for imaging of prion plaques and treatment of transmissible spongiform encephalopathies. Journal of neurochemistry, 2006, Volume: 99, Issue:1 Topics: Animals; Animals, Genetically Modified; Blood-Brain Barrier; Cell Line, Tumor; Cricetinae; Disease Models, Animal; Indicators and Reagents; Mice; Neuroblastoma; Prion Diseases; Prions; Styrenes; Thiazoles	2006
Library synthesis and screening: 2,4-diphenylthiazoles and 2,4-diphenyloxazoles as potential novel prion disease therapeutics. Journal of medicinal chemistry, 2007, Mar-22, Volume: 50, Issue:6 Topics: Animals; Cell Line; Combinatorial Chemistry Techniques; Humans; Mice; Oxazoles; Prion Diseases; Protein Binding; PrPC Proteins; PrPSc Proteins; Structure-Activity Relationship; Surface Plasmon Resonance; Thiazoles	2007
Polymerization of human prion peptide HuPrP 106-126 to amyloid in nucleic acid solution. Archives of virology, 1998, Volume: 143, Issue:7 Topics: Amino Acid Sequence; Amyloid; Anilino Naphthalenesulfonates; Animals; Benzothiazoles; DNA; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Polymers; Prion Diseases; Prions; Protein Binding; Solutions; Thiazoles	1998
Prion peptide 106-126 as a model for prion replication and neurotoxicity. Frontiers in bioscience : a journal and virtual library, 2002, Apr-01, Volume: 7 Topics: Benzothiazoles; Cell Line; Detergents; Fluorescent Dyes; Humans; Membrane Proteins; Microscopy, Fluorescence; Models, Biological; Mutation; Neurons; Peptide Fragments; Prion Diseases; Prions; Protein Transport; PrPC Proteins; Solubility; Thiazoles; Tumor Cells, Cultured	2002