thiazoles has been researched along with Cognitive Decline in 167 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 142 (85.03) | 24.3611 |
| 2020's | 25 (14.97) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, L; Gordon, ML; Li, Y; Liu, F; Lou, F; Wang, Y; Zhang, N; Zhang, Y | 1 |
| Aso, Y; Kimura, N; Matsubara, E | 1 |
| Aikawa, M; Aso, Y; Kimura, N; Matsubara, E; Sasaki, Y; Yabuuchi, K | 1 |
| Arahata, Y; Bundo, M; Ikenuma, H; Ito, K; Iwata, K; Kato, T; Kimura, Y; Nakamura, A; Nihashi, T; Okamura, N; Sakurai, K; Sakurai, T; Suzuki, K; Takeda, A; Washimi, Y; Yamaoka, A; Yanai, K | 1 |
| da Motta, KP; Domingues, NLC; Luchese, C; Santos, BF; Wilhelm, EA | 1 |
| Bae, J; Byun, MS; Han, SH; Hwang, D; Jeong, H; Kim, H; Kim, YK; Lee, DY; Lee, H; Lee, SW; Mook-Jung, I; Park, JC; Shin, SA; Yi, D | 1 |
| Hattori, H; Ishii, K; Ito, K; Iwata, K; Iwatsubo, T; Kato, T; Kimura, Y; Nakamura, A; Okada, Y; Senda, M; Toyama, H | 1 |
| Abe, K; Asada, K; Deguchi, K; Higashi, Y; Hishikawa, N; Ikeda, M; Ikeda, Y; Kimura, N; Kojo, M; Kuroda, T; Lee, LJ; Matsubara, E; Morihara, R; Nakano, Y; Ohta, Y; Okamoto, K; Ono, K; Osakada, Y; Senga, T; Shang, J; Shi, X; Shoji, M; Takao, Y; Takatama, M; Takemoto, M; Tanaka, K; Wakutani, Y; Yamashita, T | 1 |
| Allison, SL; Asthana, S; Betthauser, TJ; Carlsson, CM; Chin, NA; Christian, BT; Clark, LR; Cody, KA; Erickson, CM; Johnson, SC; Jonaitis, EM; Koscik, RL; Mueller, KD; Rowley, HA; Stone, CK | 1 |
| Byun, MS; Jeon, SY; Jung, GJ; Jung, JH; Kang, KM; Kim, YK; Lee, DY; Lee, JH; Lee, JY; Lee, Y; Shin, SA; Sohn, BK; Sohn, CH; Yi, D | 1 |
| Byun, MS; Jeon, SY; Kim, JW; Kim, YK; Ko, K; Lee, DY; Lee, JH; Lee, JY; Shin, SA; Sohn, BK; Sohn, CH; Yi, D | 1 |
| Boles Ponto, LL; DeVries, SD; Harlynn, EL; Magnotta, VA; Menda, Y; Moser, DJ; Oleson, JJ; Schultz, SK; Wemmie, JA | 1 |
| Bu, SH; Byun, BH; Chi, DY; Ha, JH; Kim, BI; Kim, JH; Kim, KM; Kim, YK; Ko, IO; Lee, JY; Lee, KC; Lim, SM; Park, SY | 2 |
| Brew, BJ; Cysique, LA; Howdle, GC; Johnson, K; Kassem, MS; Quidé, Y; Rae, CD | 1 |
| DeCarli, C; Farias, ST; Fletcher, E; Han, JW; Harvey, D; Jagust, W; Johnson, DK; Maillard, P; Martinez, O; Mungas, D; Olichney, JM; Villeneuve, S | 1 |
| Matsuyama, K; Sora, I; Yamamoto, Y | 1 |
| Araklitis, G; Cardozo, L; Robinson, D | 1 |
| Banzo, I; Bravo, M; Casado, A; Cerveró, A; de Arcocha-Torres, M; García-Martínez, M; Goikoetxea, A; Jimenez-Bonilla, J; Kazimierczak, M; Lage, C; López-de-Eguileta, A; López-García, S; Pozueta, A; Rodríguez-Rodríguez, E; Sánchez-Juan, P | 1 |
| Brucki, SMD; Buchpiguel, CA; Busatto, GF; Costa, NAD; Coutinho, AM; Duran, FLS; Faria, DP; Forlenza, OV; Nitrini, R; Porto, FHG; Squarzoni, P; Yassuda, MS | 1 |
| Apple, AC; Asken, BM; Boxer, AL; Brathaban, N; Casaletto, KB; Elahi, FM; Fernandes, N; Karydas, A; Kramer, JH; La Joie, R; Lindbergh, CA; Miller, BL; Rabinovici, GD; Rojas, JC; Staffaroni, AM; Strom, A; Wang, P; Weiner-Light, S; You, M | 1 |
| Arani, A; Boeve, BF; Botha, H; Cogswell, PM; Graff-Radford, J; Gunter, JL; Jack, CR; Jones, DT; Kantarci, K; Knopman, DS; Lowe, VJ; Mielke, MM; Petersen, RC; Schwarz, CG; Senjem, ML; Therneau, TM; Vemuri, P; Weigand, SD; Wiste, HJ | 1 |
| Brucki, SMD; Buchpiguel, CA; Busatto Filho, G; Carvalho, CL; Coutinho, AMN; da Costa, NA; de Paula Faria, D; Duran, FLS; Forlenza, OV; Leite, CDC; Nitrini, R; Pachi, CGDF; Porto, FHG; Rosa, PGP; Squarzoni, P; Torralbo, L | 1 |
| Ataka, T; Kimura, N; Matsubara, E; Mizukami, T; Uchida, H | 1 |
| Abe, K; Kitajima, K; Koyama, H; Ohigashi, M; Osugi, K; Takeda, M; Yamakado, K; Yoshikawa, H | 1 |
| Heeman, F; Hendriks, J; Lammertsma, AA; Lopes Alves, I; Tolboom, N; van Berckel, BNM; Yaqub, M | 1 |
| Asllani, I; Chappell, MA; Golay, X; Günther, M; Hernandez-Tamames, JA; McConnell, FAK; van Osch, MJ | 1 |
| Byun, MS; Cho, HJ; Choe, YM; Han, SH; Jung, ES; Kang, S; Kim, EH; Kim, YK; Lee, DY; Mook-Jung, I; Park, JC; Won, SJ; Yi, D | 1 |
| Arnold, M; Baillie, RA; Blach, C; Casanova, R; Chang, R; Dallmann, G; Demirkan, A; Doraiswamy, PM; Han, X; Hankemeier, T; Harms, AC; Henrion, MYR; Jack, JR; John-Williams, LS; Kaddurah-Daouk, R; Kastenmüller, G; Kim, S; Klavins, K; Koal, T; Legido-Quigley, C; Louie, G; Lucas, JE; MahmoudianDehkordi, S; Massaro, T; Moseley, MA; Motsinger-Reif, A; Nho, K; Risacher, SL; Rotroff, DM; Saykin, AJ; Shaw, LM; Shen, L; Suhre, K; Tenenbaum, JD; Thambisetty, M; Thompson, JW; Toledo, JB; Trojanowski, JQ; van der Lee, SJ; van Duijn, CM; Varma, S; Weiner, MW; Zhu, H; Zhu, K | 1 |
| Amariglio, R; Chhatwal, J; Hanseeuw, B; Johnson, KA; McLaren, DG; Pascual-Leone, A; Rentz, D; Sperling, RA; Vannini, P | 1 |
| Hong, YJ; Kim, CM; Kim, JE; Kim, JS; Lee, JH; Na, DL; Roh, JH; Seo, SW | 1 |
| Aanerud, J; Amidi, A; Borghammer, P; Brooks, DJ; Brændgaard, H; Edison, P; Eriksson, BO; Eskildsen, SF; Gottrup, H; Hansen, KV; Hinz, R; Ismail, R; Lund, TE; Mårup, FH; Parbo, P; Pavese, N; Stokholm, MG; Tietze, A | 1 |
| Buckley, RF; Chhatwal, JP; Hanseeuw, BJ; Hedden, T; Johnson, KA; Marshall, G; Papp, KV; Rentz, DM; Schultz, AP; Sepulcre, J; Smith, EE; Sperling, RA | 1 |
| Almkvist, O; Alongi, P; Bettinardi, V; Cerami, C; Chiotis, K; Gianolli, L; Iaccarino, L; Nordberg, A; Perani, D; Wall, A | 1 |
| Bulova, P; Christian, BT; Devenny, D; Handen, BL; Hardison, R; Hartley, SL; Johnson, SC; Klunk, WE; Lao, PJ; Mihaila, I | 1 |
| Abe, Y; Goto, M; Kimura, N; Matsubara, E; Takemaru, M | 1 |
| Ackermann, M; Denver, P; Kelly, P; Konerding, MA; Mitchell, CA; Satchell, SC | 1 |
| Cai, L; Cheng, Y; Gordon, ML; Li, Y; Wang, Y; Xing, M; Zhang, L; Zhang, N | 1 |
| Adachi, K; Akamatsu, G; Ikari, Y; Nishio, T; Senda, M | 1 |
| Aghjayan, SL; Amariglio, RE; Buckley, RF; Hanseeuw, B; Jackson, JD; Johnson, KA; Mormino, EC; Properzi, MJ; Rentz, DM; Schultz, AP; Sperling, RA; Vannini, P | 1 |
| Devanand, DP; Kumar, D; Lan, MJ; Mann, JJ; Miller, JM; Ogden, RT; Parsey, RV; Pelton, GH; Pradhaban, G; Rubin-Falcone, H; Stern, Y; Zanderigo, F | 1 |
| Ayakta, N; Baker, SL; Bejanin, A; Cantwell, A; Gorno-Tempini, ML; Jagust, WJ; Janabi, M; Kramer, JH; La Joie, R; Lauriola, M; Miller, BL; Miller, ZA; O'Neil, JP; Rabinovici, GD; Rosen, HJ; Schonhaut, DR; Sosa, N | 1 |
| Venugopalan, J; Wang, MD | 1 |
| Brodtmann, A; Connelly, A; Dhollander, T; Mito, R; Raffelt, D; Rowe, CC; Salvado, O; Tournier, JD; Vaughan, DN; Villemagne, VL | 1 |
| Albert, M; Li, S; Miller, MI; Moghekar, A; Mori, S; Pettigrew, C; Selnes, O; Soldan, A; Wang, MC; Zhu, Y | 1 |
| Boeve, BF; Botha, H; Graff-Radford, J; Jack, CR; Jones, DT; Knopman, DS; Lowe, VJ; Machulda, MM; Mantyh, WG; Murray, ME; Parisi, JE; Petersen, RC; Przybelski, SA; Senjem, ML; Wiste, HJ | 1 |
| Arahata, Y; Bajo, R; Bundo, M; Cuesta, P; Diers, K; Endo, H; Fernández, A; Fukuda, K; Hattori, H; Ito, K; Iwata, K; Kato, T; Kuratsubo, I; Maestú, F; Nakamura, A; Sakurai, T; Takeda, A; Washimi, Y | 1 |
| Bombicz, M; Gesztelyi, R; Hortobágyi, T; Juhász, B; Kiss, R; Kurucz, A; Pósa, A; Priksz, D; Szabó, R; Szilvássy, Z; Trencsényi, G; Varga, B | 1 |
| Aakre, JA; Alhurani, R; Coloma, P; Geda, YE; Jack, CR; Knopman, DS; Kremers, WK; Lowe, VJ; Machulda, MM; Mielke, MM; Petersen, RC; Roberts, RO; Schauble, B; Vassilaki, M | 1 |
| Bartenstein, P; Brendel, M; Hanaoka, K; Hosokawa, C; Ishii, K; Kaida, H; Murakami, T; Rominger, A; Sauerbeck, J; Scheiwein, FT | 1 |
| Byun, MS; Kang, SK; Kim, YK; Lee, DS; Lee, DY; Lee, JS; Seo, S; Shin, SA | 1 |
| Aakre, JA; Alhurani, RE; Geda, YE; Jack, CR; Knopman, DS; Kremers, WK; Lowe, VJ; Machulda, MM; Mielke, MM; Petersen, RC; Roberts, RO; Staubo, SC; Syrjanen, JA; Vassilaki, M | 1 |
| Abe, T; Ataka, S; Hasegawa, I; Itoh, Y; Kawabe, J; Kikukawa, T; Mino, T; Saito, H; Takeuchi, J; Wada, Y; Watanabe, Y | 1 |
| Cho, SH; Ewers, M; Im, K; Jang, H; Kim, HJ; Kim, SE; Kim, SJ; Kim, ST; Kim, Y; Kwon, H; Moon, SH; Na, DL; Seo, SW | 1 |
| Ances, BM; Babulal, GM; Benzinger, TLS; Fagan, AM; Grant, EA; Hassenstab, J; Head, D; Holtzman, DM; Morris, JC; Roe, CM; Schindler, SE; Stout, SH; Xiong, C | 1 |
| Abulafia, C; Castro, MN; Curiel-Cid, R; Drucaroff, LJ; Duarte-Abritta, B; Guinjoan, SM; Loewenstein, D; Nemeroff, CB; Sánchez, SM; Sevlever, G; Vázquez, S; Vigo, DE; Villarreal, MF | 1 |
| Jang, H; Jang, YK; Kim, HJ; Lee, JS; Lockhart, SN; Na, DL; Noh, Y; Park, JY; Seo, SW; Seong, JK | 1 |
| Bateman, RJ; Benzinger, TLS; Berge, G; Bråthen, G; Bu, G; Fagan, A; Grøntvedt, GR; Karch, CM; Lauridsen, C; Morris, JC; Møller, I; Nielsen, HM; Nordberg, A; Patra, K; Rodriguez-Vieitez, E; Sando, SB; Twohig, D; White, LR | 1 |
| Arbizu, J; Boada, M; Martínez-Lage, P; Monleón, I; Munuera, J; Pérez-Grijalba, V; Pesini, P; Romero, J; Ruiz, A; San-José, I; Sarasa, L; Sarasa, M; Tárraga, L | 1 |
| Barthel, H; Gertz, HJ; Hesse, S; Hoffmann, KT; Luthardt, J; Patt, M; Sabri, O; Tiepolt, S; Weise, D | 1 |
| Boellaard, R; De Deyn, PP; de Jong, BM; Dierckx, RAJO; Peretti, DE; Reesink, FE; Vállez García, D; van der Goot, T | 1 |
| Amariglio, RE; Becker, JA; Chhatwal, JP; Donovan, NJ; Gatchel, JR; Hanseeuw, BJ; Johnson, KA; Marshall, GA; Muniz, MC; Papp, KV; Rentz, DM; Schultz, AP; Sperling, RA | 1 |
| Al Keridy, W; Dao, E; Hsiung, GR; Liu-Ambrose, T; Nicklin, E; Shahinfard, E; Sossi, V; Tam, R | 1 |
| Bertoldo, A; Bodini, B; Brooks, DJ; Edison, P; Marchitelli, L; Schubert, JJ; Stankoff, B; Tonietto, M; Turkheimer, FE; Veronese, M | 1 |
| Banzo, I; De Arcocha-Torres, M; De la Fuente-Gómez, F; Jiménez-Bonilla, JF; Martínez-Amador, N; Martínez-Rodríguez, I; Quirce, R; Rodríguez, E; Sánchez-Juan, P; Sánchez-Salmón, A | 1 |
| Scheltens, P; Teunissen, CE; Tijms, BM; van Paasen, AJL; Vermunt, L; Visser, PJ | 1 |
| Hwang, H; Rhim, H | 1 |
| Bunai, T; Kakimoto, A; Ouchi, Y; Terada, T; Yoshikawa, E | 1 |
| Blennow, K; Jack, C; Kern, S; Knopman, DS; Kremers, WK; Machulda, MM; Mielke, MM; Petersen, RC; Skoog, I; Syrjanen, JA; Vemuri, P; Zetterberg, H | 1 |
| Barkhof, F; Dicks, E; Groot, C; Ossenkoppele, R; Scheltens, P; Twisk, J; van der Flier, WM; van Loenhoud, AC; Wink, AM | 1 |
| Bowie, CR; Brown, EE; Caravaggio, F; Fischer, CE; Flint, A; Gerretsen, P; Graff-Guerrero, A; Herrmann, N; Mah, L; Mulsant, BH; Pollock, BG; Rajji, TK; Rashidi-Ranjbar, N; Voineskos, AN | 1 |
| Hansson, O; Insel, PS; Lim, YY; Mackin, RS; Maruff, PT; Masters, CL; Mattsson, N; Mormino, E; Palmqvist, S; Stomrud, E; Weiner, M | 1 |
| Brickman, AM; Griffith, EY; Guzman, VA; Meier, IB; Muraskin, J; Narkhede, A; Provenzano, FA; Tosto, G; Wasserman, BT; Zimmerman, ME | 1 |
| Aisen, PS; Foroud, T; Inlow, M; Jagust, WJ; Kim, S; Koeppe, RA; Mathis, CA; Petersen, RC; Risacher, SL; Saykin, AJ; Shaw, LM; Shen, L; Soares, H; Swaminathan, S; Trojanowski, JQ; Weiner, MW; West, JD; Yoder, KK | 1 |
| Ames, D; Ashwood, T; Bush, A; Darby, D; Ellis, KA; Harrington, K; Jaeger, J; Lachovitzki, R; Lim, YY; Martins, RN; Maruff, P; Masters, CL; Rowe, CC; Stöffler, A; Szoeke, C; Villemagne, VL | 1 |
| Albin, RL; Burke, JF; Frey, KA; Gilman, S; Giordani, B; Koeppe, RA | 1 |
| Aizenstein, HJ; DeKosky, ST; Kamboh, MI; Klunk, WE; Kuller, LH; Lopez, OL; Lopresti, BJ; Mathis, CA; McDade, EM; Price, JC; Rosario, BL; Saxton, JA; Snitz, BE; Weissfeld, LA | 1 |
| Rowe, CC; Villemagne, VL | 2 |
| Bennett, DA; Bradshaw, EM; Chibnik, LB; De Jager, PL; Evans, DA; Imboywa, S; Johnson, K; Keenan, BT; Lee, M; Morris, MC; Ottoboni, L; Raj, T; Rosenkrantz, LL; Schneider, JA; Sperling, RA; Tang, A; Von Korff, A | 1 |
| Hatashita, S; Yamasaki, H | 1 |
| Brück, A; Helenius, H; Helin, S; Koikkalainen, J; Koivunen, J; Någren, K; Parkkola, R; Rinne, JO; Scheinin, NM; Viitanen, M; Virta, JR | 1 |
| Boellaard, R; Foster-Dingley, JC; Lammertsma, AA; Ossenkoppele, R; Scheltens, P; Tolboom, N; van Berckel, BN; Windhorst, AD; Yaqub, M | 1 |
| Case, M; Hake, A; Hochstetler, H; Schuh, K; Sun, J; Trzepacz, PT; Witte, MM; Yu, P | 1 |
| Johansson, J; Karrasch, M; Kemppainen, NM; Koivunen, J; Någren, K; Parkkola, R; Rinne, JO; Rokka, J; Scheinin, NM; Toivonen, JT | 1 |
| Chin, J; Cho, H; Choe, YS; Jang, EY; Jeon, S; Kim, CH; Kim, GH; Kim, HJ; Kim, JH; Lee, J; Lee, JM; Lee, KH; Na, DL; Noh, Y; Seo, SW; Seong, JK; Ye, BS; Yoon, CW | 1 |
| Arakawa, R; Eguchi, Y; Fukumura, T; Higuchi, M; Ito, H; Kodaka, F; Miyoshi, M; Okamura, N; Ono, M; Shimada, H; Shinotoh, H; Suhara, T; Takahashi, H; Takano, H; Yanai, K | 1 |
| Amariglio, RE; Becker, JA; Donovan, NJ; Gidicsin, CM; Johnson, KA; Lorius, N; Marshall, GA; Maye, J; Pepin, LC; Rentz, DM; Sperling, RA | 1 |
| Arai, A; Arai, H; Furukawa, K; Furumoto, S; Iwata, R; Kaneta, T; Kudo, Y; Okamura, N; Takahashi, S; Takanami, K; Tashiro, M; Yanai, K | 1 |
| Chin, J; Cho, H; Cho, J; Choe, YS; Jeon, S; Kim, C; Kim, CH; Kim, GH; Kim, HJ; Kim, JH; Kim, JS; Kim, ST; Lee, JH; Lee, JM; Lee, KH; Na, DL; Noh, Y; Park, SE; Seo, SW; Seong, JK; Weiner, MW; Ye, BS; Yoon, CW | 1 |
| Abrahamson, EE; He, B; Ikonomovic, MD; Mufson, EJ; Nadeem, M; Perez, SE; Scheff, SW; Wuu, J | 1 |
| Chen, X; Li, M; Liu, X; Wang, S; Xiong, Y; Zhu, H | 1 |
| Cohen, AD; Klunk, WE | 1 |
| Ishibashi, K; Ishii, K; Ishiwata, K; Miura, Y; Oda, K | 1 |
| Gauthier, S; Heurling, K; Leuzy, A; Rosa-Neto, P; Zimmer, ER | 1 |
| Hermann, DM | 1 |
| Hirano, H; Kajiya, Y; Tani, A; Yokoyama, S; Yoshinaga, T | 1 |
| Drzezga, A; Förster, S; Förstl, H; Göttler, J; Grimmer, T; Koch, K; Kurz, A; Manoliu, A; Myers, NE; Neitzel, J; Pasquini, L; Riedl, V; Sorg, C; Wohlschläger, AM | 1 |
| Feng, J; Hyde, C; McShane, R; Noel-Storr, AH; Smailagic, N; Takwoingi, Y; Zhang, S | 1 |
| Chen, TF; Cheng, TW; Chiu, MJ; Horng, HE; Huang, YY; Shiue, CY; Tzen, KY; Wen, HP; Yang, SY | 1 |
| Ashraf, A; Brooks, DJ; Edison, P; Fan, Z | 1 |
| Aizenstein, HJ; Becker, JT; Cohen, A; Coleman, RL; DeKosky, ST; Ikonomovic, M; Klunk, WE; Kuller, LH; Lopez, OL; Mathis, C; McDade, E; Price, J; Snitz, B; Weissfeld, L | 1 |
| Arai, A; Arai, H; Fukuda, H; Iwata, R; Kaneta, T; Kudo, Y; Okamura, N; Takahashi, S; Takanami, K; Tashiro, M; Yanai, K | 1 |
| Han, B; He, W; Li, G; Liu, D; Radua, J; Sun, Z | 1 |
| Ames, D; Bourgeat, P; Ellis, KA; Harrington, K; Lim, YY; Martins, RN; Maruff, P; Masters, CL; Pietrzak, RH; Rembach, A; Rowe, CC; Salvado, O; Snyder, PJ; Villemagne, VL | 1 |
| Apostolova, LG; Avila, D; Elashoff, D; Hwang, KS; Jack, CR; Jagust, WJ; Kohannim, O; Shaw, L; Sokolow, S; Teng, E; Thompson, PM; Trojanowski, JQ; Weiner, MW | 1 |
| Almkvist, O; Carter, SF; Chiotis, K; Leuzy, A; Nordberg, A; Wall, A | 1 |
| Ametamey, SM; Buck, A; Burger, C; Gietl, AF; Gruber, E; Hock, C; Kälin, AM; Kuhn, FP; Leh, SE; Mu, L; Nitsch, RM; Riese, F; Saake, A; Schibli, R; Seifert, B; Unschuld, PG; Warnock, G | 1 |
| Alejandra, A; Claudio, W; Federico, N; Gabriela, C; Griselda, R; Gustavo, S; Janus, K; Jorge, C; Julieta, RM; Leonardo, T; Marcos, FS; Patricio, CM; Ramon, L; Ricardo, A; Salvador, G; Santiago, P; Silvia, V | 1 |
| Kim, J; Lee, JM; Park, H; Seo, J; Son, SJ | 1 |
| Hwang, J; Kim, CM; Koh, JY; Lee, JH; Lee, JM; Roh, JH | 1 |
| Arima, K; Ito, K; Matsuda, H; Motohashi, N; Nakagome, K; Nakata, Y; Omachi, Y; Sakata, M; Sato, N | 1 |
| Fan, Y; Fu, L; Liu, L; Tian, J; Xu, B; Zhang, J; Zhang, X | 1 |
| Carter, SF; Chiotis, K; Farid, K; Nordberg, A; Savitcheva, I | 1 |
| Byun, MS; Choe, YM; Choi, HJ; Lee, DY; Lee, JM; Seo, EH; Sohn, BK; Woo, JI; Yi, D | 1 |
| Banzo, I; Carril, JM; De Arcocha-Torres, M; Jiménez-Bonilla, JF; Martínez-Rodríguez, I; Quirce, R; Sánchez-Juan, P | 1 |
| Hosokawa, C; Hosono, M; Hyodo, T; Ishii, K; Kimura, Y; Murakami, T; Sakaguchi, K; Shimamoto, K; Usami, K; Yamazoe, Y | 1 |
| Johansson, J; Joutsa, J; Kemppainen, N; Någren, K; Parkkola, R; Rinne, JO; Rokka, J; Scheinin, NM | 1 |
| Colijn, MA; Grossberg, GT | 1 |
| Boeve, BF; Gunter, JL; Jack, CR; Jones, DT; Kantarci, K; Knopman, DS; Lowe, VJ; Lundt, ES; Machulda, MM; Mielke, MM; Petersen, RC; Roberts, RO; Senjem, ML; Vemuri, P; Weigand, SD; Wiste, HJ | 1 |
| Albers, M; Alverio, J; Amariglio, R; Becker, JA; Betensky, RA; Chhatwal, J; Dickerson, B; Gomez-Isla, T; Hyman, B; Johnson, KA; Judge, K; Marshall, G; Mauro, S; Mormino, E; Papp, K; Pepin, L; Philiossaint, M; Rentz, D; Schultz, A; Sepulcre, J; Shoup, T; Sperling, R; Vasdev, N; Yokell, D | 1 |
| Alexopoulos, P; Drzezga, A; Förster, S; Förstl, H; Goldhardt, O; Grimmer, T; Kurz, A; Ortner, M; Sorg, C; Wutz, C | 1 |
| Bayer, S; Gomperts, SN; Growdon, JH; Johnson, KA; Locascio, JJ; Marquie, M | 1 |
| Almkvist, O; Carter, SF; Chiotis, K; Långström, B; Leuzy, A; Nordberg, A; Rodriguez-Vieitez, E; Saint-Aubert, L; Schöll, M; Wall, A | 1 |
| Ayakta, N; Baker, SL; Bettcher, BM; Cantwell, A; Gorno-Tempini, ML; Jagust, WJ; Janabi, M; Kramer, JH; Lazaris, A; Lockhart, SN; Miller, BL; Miller, ZA; O'Neil, JP; Ossenkoppele, R; Rabinovici, GD; Santos, M; Schöll, M; Schonhaut, DR; Vogel, J; Vossel, KA | 1 |
| Chiotis, K; Leuzy, A; Nordberg, A; Rodriguez-Vieitez, E; Saint-Aubert, L; Wall, A | 1 |
| Chin, J; Choe, YS; Chun, P; Jung, NY; Kim, C; Kim, HJ; Kim, JS; Kim, S; Kim, ST; Kim, YJ; Kwon, H; Lee, JH; Lee, JM; Lee, KH; Na, DL; Seo, SW; Weiner, MW; Woo, SY; Yang, JJ | 1 |
| Banzo, I; Bravo-Ferrer, Z; Carril, JM; De Arcocha-Torres, M; Jiménez-Bonilla, JF; Lavado-Pérez, C; Martínez-Rodríguez, I; Quirce, R; Rodríguez-Rodríguez, E; Sánchez-Juan, P | 1 |
| Baek, JH; Cho, HJ; Han, SH; Hong, HS; Hwang, D; Jeong, H; Kang, S; Kim, H; Kim, YH; Lee, SJ; Mook-Jung, I; Na, DL; Seo, SW; Yi, EC | 1 |
| Anderl-Straub, S; Beer, A; Blennow, K; Blesa, R; Castelo-Branco, M; Chiotis, K; de Mendonça, A; Fortea, J; Hasselbalch, SG; Herukka, SK; Johansson, J; Leuzy, A; Lleó, A; Nordberg, A; Otto, M; Pannee, J; Portelius, E; Rinne, JO; Santana, I; von Arnim, CA; Zetterberg, H | 1 |
| Betensky, RA; Hanseeuw, BJ; Johnson, KA; Schultz, AP; Sperling, RA | 1 |
| Amariglio, R; Hanseeuw, B; Hedden, T; Johnson, KA; LaPoint, M; Marshall, GA; Mormino, EC; Papp, KV; Rentz, DM; Schultz, AP; Sperling, RA | 1 |
| Gunter, JL; Jack, CR; Kemp, BJ; Lowe, VJ; Petersen, RC; Schwarz, CG; Senjem, ML; Spychalla, AJ; Tosakulwong, N; Vemuri, P; Weigand, SD | 1 |
| Caso, C; Dickerson, BC; Gomperts, SN; Growdon, JH; Johnson, K; Locascio, JJ; Makaretz, SJ; Schultz, A; Sperling, R; Vasdev, N | 1 |
| Aisen, PS; Amariglio, R; Chhatwal, J; Donohue, MC; Donovan, N; Gatchel, JR; Hanseeuw, BJ; Jackson, J; Johnson, KA; Marshall, GA; Mormino, EC; Papp, KV; Quiroz, YT; Rentz, DM; Schultz, AP; Sperling, RA | 1 |
| Abrahamson, EE; Fish, KN; Ikonomovic, MD; Mi, Z; Mufson, EJ; Ryu, AY; Sweet, RA | 1 |
| Abe, Y; Gotou, M; Kimura, N; Matsubara, E; Mizukami, K; Takahashi, R; Uchida, H | 1 |
| Alegret, M; Arbizu, J; Becker, JT; Boada, M; Buendía, M; Espinosa, A; Giménez, J; Hendrix, SB; Hernández, I; Ibarria, M; Lafuente, A; Landau, SM; Martínez-Lage, P; Munuera, J; Pesini, P; Pujadas, F; Ruiz, A; Ruiz, S; San José, I; Sarasa, M; Sotolongo-Grau, O; Tárraga, L; Tejero, MA; Valero, S | 1 |
| Hatashita, S; Wakebe, D | 1 |
| Almkvist, O; Engler, H; Forsberg, A; Kadir, A; Långström, B; Nordberg, A; Wall, A | 1 |
| Evin, G; Laughton, KM; Li, QX; Lim, NK; Masters, CL; McLean, CA; Rowe, CC; Soon, CP; Villemagne, VL | 1 |
| Jagust, WJ | 1 |
| Arai, H; Fukuda, H; Furukawa, K; Furumoto, S; Iwata, R; Kaneta, T; Kudo, Y; Minoshima, S; Okamura, N; Takahashi, S; Tashiro, M; Yanai, K | 1 |
| Ishii, K | 1 |
| Aisen, P; Ewers, M; Insel, P; Jagust, WJ; Petersen, RC; Schuff, N; Shaw, L; Trojanowski, JQ; Weiner, MW | 1 |
| Chui, HC; DeCarli, CC; Jagust, WJ; Mack, W; Marchant, NL; Reed, BR | 1 |
| Burns, JM; Honea, RA; Townley, RA; Vidoni, ED | 1 |
| Blomquist, G; Engler, H; Forsberg, A; Långström, B; Nordberg, A | 1 |
| Almkvist, O; Carter, SF; Engler, H; Långström, B; Nordberg, A; Schöll, M; Wall, A | 1 |
| Ding, Y; Feng, J; Guo, Y; Han, D; Tan, X; Zhang, S | 1 |
| Ames, D; Chételat, G; Ellis, KA; Jones, G; Martins, RN; Masters, CL; Rowe, CC; Villain, N; Villemagne, VL | 1 |
| Adriaanse, SF; Barkhof, F; Boellaard, R; Foster-Dingley, JC; Lammertsma, AA; Ossenkoppele, R; Scheltens, P; Tolboom, N; van Berckel, BN; van der Flier, WM; Windhorst, AD; Yaqub, M | 1 |
| Brooks, DJ; Gelosa, G | 1 |
| Ames, D; Bourgeat, P; Chételat, G; Ellis, KA; Eustache, F; Grassiot, B; Jones, G; Martins, RN; Masters, CL; Rowe, CC; Salvado, O; Villain, N; Villemagne, VL | 1 |
| Burns, JM; Honea, RA; Swerdlow, RH; Vidoni, ED | 1 |
| Gomperts, SN; Growdon, JH; Johnson, KA; Locascio, JJ; Marquie, M; Maye, J; Rentz, DM; Santarlasci, AL | 1 |
| Gallagher, M; Koh, MT; Rosenzweig-Lipson, S | 1 |
| Bradley, MA; Fister, SX; Lovell, MA | 1 |
| Baig, I; Beckett, TL; Holler, CJ; Keller, JN; LeVine, H; Matveev, S; Murphy, MP; Niedowicz, DM; Webb, RL | 1 |
| Aalto, S; Helin, S; Karrasch, M; Koivunen, J; Någren, K; Rinne, JO; Scheinin, NM; Vahlberg, T; Viitanen, M | 1 |
| Andersen, A; Brooks, DJ; Dupont, P; Hasselbalch, S; Ivanoiu, A; Korner, A; Minthon, L; Nelissen, N; Salmon, E; Van Laere, K; Vandenberghe, R | 1 |
| Drzezga, A; Förster, S; Förstl, H; Grimmer, T; Kurz, A; Ortner, M; Perneczky, R; Wutz, C | 1 |
| Ames, D; Bush, AI; Ellis, KA; Faux, NG; Gupta, VB; Henley, D; Laws, SM; Li, QX; Martins, RN; Masters, CL; Pike, KE; Rowe, CC; Szoeke, C; Taddei, K; Verdile, G; Villemagne, VL | 1 |
| Adriaanse, SM; Barkhof, F; Binnewijzend, MA; Boellaard, R; Lammertsma, AA; Ossenkoppele, R; Rombouts, SA; Sanz-Arigita, EJ; Scheltens, P; Tolboom, N; van Assema, DM; van Berckel, BN; van der Flier, WM; Windhorst, AD; Wink, AM; Yaqub, M | 1 |
| Gomperts, SN; Growdon, JH; Johnson, KA; Locascio, JJ; Marquie, M; Rentz, D; Santarlasci, A | 1 |
| Brooks, DJ; Carter, SF; Edison, P; Gelosa, G; Herholz, K; Hinz, R; Nordberg, A; Rinne, JO | 1 |
| Chui, HC; DeCarli, C; Dhada, R; Jagust, WJ; Kriger, S; Mack, WJ; Madison, CM; Marchant, NL; Mungas, DM; Reed, BR; Sanossian, N; Weiner, MW | 1 |
11 review(s) available for thiazoles and Cognitive Decline
| Article | Year |
|---|---|
Cognitive Effects of Anticholinergic Load in Women with Overactive Bladder.
Topics: Acetanilides; Aged; Behavior Therapy; Benzilates; Blood-Brain Barrier; Cholinergic Antagonists; Cognitive Dysfunction; Female; Humans; Muscarinic Antagonists; Nortropanes; Thiazoles; Urinary Bladder, Overactive | 2020 |
Partial volume correction in arterial spin labeling perfusion MRI: A method to disentangle anatomy from physiology or an analysis step too far?
Topics: Algorithms; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Carbon Radioisotopes; Cerebral Arteries; Cognitive Dysfunction; Entorhinal Cortex; Hippocampus; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Membrane Glycoproteins; Nerve Tissue Proteins; Neuroimaging; Organ Size; Perfusion; Positron-Emission Tomography; Pyridines; Pyrrolidinones; Radiopharmaceuticals; Spin Labels; Synaptic Vesicles; Thiazoles | 2021 |
Amyloid imaging with PET in early Alzheimer disease diagnosis.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Asymptomatic Diseases; Brain; Carbon Radioisotopes; Chromosome Aberrations; Cognitive Dysfunction; Diagnosis, Differential; Disease Progression; DNA Mutational Analysis; Fluorine Radioisotopes; Genetic Carrier Screening; Humans; Positron-Emission Tomography; Prognosis; Statistics as Topic; Thiazoles | 2013 |
Pittsburgh compound B retention and progression of cognitive status--a meta-analysis.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Aniline Compounds; Cognitive Dysfunction; Disease Progression; Humans; Middle Aged; Positron-Emission Tomography; Thiazoles | 2014 |
Early detection of Alzheimer's disease using PiB and FDG PET.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Brain; Cognition; Cognitive Dysfunction; Fluorodeoxyglucose F18; Glucose; Humans; Positron-Emission Tomography; Thiazoles | 2014 |
Use of amyloid PET across the spectrum of Alzheimer's disease: clinical utility and associated ethical issues.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Asymptomatic Diseases; Benzothiazoles; Brain; Carbon Radioisotopes; Cognitive Dysfunction; Dementia; Ethylene Glycols; Fluorine Radioisotopes; Humans; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2014 |
(11)C-PIB-PET for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI).
Topics: Aged; Alzheimer Disease; Aniline Compounds; Carbon Radioisotopes; Cognitive Dysfunction; Dementia; Disease Progression; Early Diagnosis; Humans; Positron-Emission Tomography; Prospective Studies; Sensitivity and Specificity; Thiazoles | 2014 |
Meta-analytic comparison between PIB-PET and FDG-PET results in Alzheimer's disease and MCI.
Topics: Alzheimer Disease; Aniline Compounds; Cognitive Dysfunction; Fluorodeoxyglucose F18; Glucose; Humans; Positron-Emission Tomography; Thiazoles | 2015 |
Amyloid and Tau Biomarkers in Subjective Cognitive Impairment.
Topics: Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Cross-Sectional Studies; Databases, Bibliographic; Humans; Longitudinal Studies; Positron-Emission Tomography; tau Proteins; Thiazoles | 2015 |
Diagnostic accuracy of 18 F-FDG and 11 C-PIB-PET for prediction of short-term conversion to Alzheimer's disease in subjects with mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Clinical Trials as Topic; Cognitive Dysfunction; Cross-Sectional Studies; Fluorodeoxyglucose F18; Humans; Positron-Emission Tomography; Radiopharmaceuticals; ROC Curve; Sensitivity and Specificity; Thiazoles | 2012 |
The prognostic value of amyloid imaging.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Aniline Compounds; Cognitive Dysfunction; Humans; Plaque, Amyloid; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Stilbenes; Thiazoles | 2012 |
6 trial(s) available for thiazoles and Cognitive Decline
| Article | Year |
|---|---|
Effect of Feru-guard 100M on amyloid-beta deposition in individuals with mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Angelica archangelica; Aniline Compounds; Atrophy; Brain; Carbon Radioisotopes; Cognitive Dysfunction; Coumaric Acids; Disease Progression; Female; Humans; Japan; Male; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2020 |
Cerebral Amyloid-β Deposition Is Associated with Impaired Gait Speed and Lower Extremity Function.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Lower Extremity; Male; Movement Disorders; Muscle Strength; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles; Walking Speed | 2019 |
In vivo assessment of amyloid-β deposition in nondemented very elderly subjects.
Topics: Adult; Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognitive Dysfunction; Double-Blind Method; Female; Humans; Male; Middle Aged; Positron-Emission Tomography; Prevalence; Thiazoles | 2013 |
Amyloid, neurodegeneration, and small vessel disease as predictors of dementia in the oldest-old.
Topics: Aged, 80 and over; Amyloid; Aniline Compounds; Brain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Dementia; Disease Progression; Double-Blind Method; Female; Geriatric Assessment; Ginkgo biloba; Humans; Longitudinal Studies; Male; Neurodegenerative Diseases; Phytotherapy; Plant Extracts; Positron-Emission Tomography; Predictive Value of Tests; Thiazoles | 2014 |
A modified method of 3D-SSP analysis for amyloid PET imaging using [¹¹C]BF-227.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Benzoxazoles; Carbon Radioisotopes; Case-Control Studies; Cognitive Dysfunction; Female; Humans; Imaging, Three-Dimensional; Male; Plaque, Amyloid; Positron-Emission Tomography; Reference Standards; Thiazoles | 2011 |
Longitudinal imaging of Alzheimer pathology using [11C]PIB, [18F]FDDNP and [18F]FDG PET.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Case-Control Studies; Cognitive Dysfunction; Female; Humans; Longitudinal Studies; Male; Middle Aged; Nitriles; Positron-Emission Tomography; Stilbenes; Thiazoles; Time Factors | 2012 |
150 other study(ies) available for thiazoles and Cognitive Decline
| Article | Year |
|---|---|
Clinical, Neuropsychological, and Neuroimaging Characteristics of Amyloid- positive vs. Amyloid-negative Patients with Clinically Diagnosed Alzheimer's Disease and Amnestic Mild Cognitive Impairment.
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Atrophy; Brain; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles | 2021 |
Novel Serum Biomarkers of Neurovascular Unit Associated with Cortical Amyloid Deposition.
Topics: Adenosine Triphosphate; Aged; Alzheimer Disease; Aniline Compounds; Biological Transport; Biomarkers; Cognitive Dysfunction; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Plaque, Amyloid; Positron-Emission Tomography; Thiazoles | 2021 |
Relationship between Cerebrospinal Fluid Matrix Metalloproteinases Levels and Brain Amyloid Deposition in Mild Cognitive Impairment.
Topics: Aged; Amyloid; Aniline Compounds; Brain; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Matrix Metalloproteinases; Regression Analysis; Thiazoles; Tissue Inhibitor of Metalloproteinases; White Matter | 2021 |
Patterns of Distribution of 18F-THK5351 Positron Emission Tomography in Alzheimer's Disease Continuum.
Topics: Aged; Alzheimer Disease; Aminopyridines; Amnesia; Aniline Compounds; Brain; Cognitive Dysfunction; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Quinolines; Radiopharmaceuticals; Severity of Illness Index; tau Proteins; Thiazoles | 2022 |
Target enzymes in oxaliplatin-induced peripheral neuropathy in Swiss mice: A new acetylcholinesterase inhibitor as therapeutic strategy.
Topics: Adenosine Triphosphatases; Analgesics; Animals; Anxiety; Benzoates; Carbamates; Cerebral Cortex; Cholinesterase Inhibitors; Cognitive Dysfunction; Disease Models, Animal; Female; Hippocampus; Indoles; Male; Mice; Oxaliplatin; Oxidative Stress; Peripheral Nervous System Diseases; Spinal Cord; Thiadiazoles; Thiazoles | 2022 |
Prognostic plasma protein panel for Aβ deposition in the brain in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Blood Chemical Analysis; Blood Proteins; Cognitive Dysfunction; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Positron-Emission Tomography; Predictive Value of Tests; Prognosis; Proteomics; Sensitivity and Specificity; Thiazoles | 2019 |
Evaluation of PiB visual interpretation with CSF Aβ and longitudinal SUVR in J-ADNI study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Cognitive Dysfunction; Cross-Sectional Studies; Databases, Factual; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Thiazoles; Time Factors | 2020 |
A New Serum Biomarker Set to Detect Mild Cognitive Impairment and Alzheimer's Disease by Peptidome Technology.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Female; Humans; Male; Mental Status and Dementia Tests; Middle Aged; Peptides; Positron-Emission Tomography; Predictive Value of Tests; Reference Values; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; tau Proteins; Thiazoles | 2020 |
Amyloid and tau imaging biomarkers explain cognitive decline from late middle-age.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Carbon Radioisotopes; Cognitive Dysfunction; Female; Fluorine Radioisotopes; Humans; Isoquinolines; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neurofibrillary Tangles; Neuropsychological Tests; Plaque, Amyloid; Positron-Emission Tomography; Prodromal Symptoms; tau Proteins; Thiazoles | 2020 |
Neuroticism, conscientiousness, and in vivo Alzheimer pathologies measured by amyloid PET and MRI.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Cerebral Cortex; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroticism; Personality; Personality Inventory; Positron-Emission Tomography; Risk Factors; Thiazoles; White Matter | 2020 |
Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Amyloid beta-Peptides; Aniline Compounds; Brain; Case-Control Studies; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Protective Factors; Republic of Korea; Thiazoles | 2020 |
Comparison of T
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Glucose; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Pilot Projects; Positron-Emission Tomography; Thiazoles | 2020 |
The correlation of neuropsychological evaluation with 11C-PiB and 18F-FC119S amyloid PET in mild cognitive impairment and Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Benzothiazoles; Carbon Radioisotopes; Cognitive Dysfunction; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Neuroimaging; Neuropsychological Tests; Positron Emission Tomography Computed Tomography; Pyridines; Radioactive Tracers; Thiazoles | 2020 |
Brain amyloid in virally suppressed HIV-associated neurocognitive disorder.
Topics: Aged; AIDS Dementia Complex; Alzheimer Disease; Amyloid; Aniline Compounds; Cognitive Dysfunction; Cohort Studies; Female; Humans; Male; Middle Aged; Positron-Emission Tomography; Thiazoles | 2020 |
Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain; Cerebrovascular Disorders; Cognition; Cognitive Dysfunction; Disease Progression; Executive Function; Female; Hippocampus; Humans; Independent Living; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Episodic; Neuropsychological Tests; Organ Size; Plaque, Amyloid; Positron-Emission Tomography; Thiazoles; White Matter | 2020 |
Evaluation of choroidal thickness in prodromal Alzheimer's disease defined by amyloid PET.
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Anthropometry; Area Under Curve; Carbon Radioisotopes; Case-Control Studies; Choroid; Cognitive Dysfunction; Cross-Sectional Studies; Disease Progression; Early Diagnosis; Female; Humans; Male; Neuroimaging; Observer Variation; Positron Emission Tomography Computed Tomography; Prodromal Symptoms; Radiopharmaceuticals; Reproducibility of Results; Thiazoles; Tomography, Optical Coherence | 2020 |
Relationship Between PET-Assessed Amyloid Burden and Visual and Verbal Episodic Memory Performance in Elderly Subjects.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Cognition; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Male; Memory, Episodic; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles | 2020 |
Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloidogenic Proteins; Amyloidosis; Aniline Compounds; Brain; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Ethylene Glycols; Female; Glial Fibrillary Acidic Protein; Humans; Male; Positron-Emission Tomography; Radiopharmaceuticals; tau Proteins; Thiazoles | 2020 |
Associations of quantitative susceptibility mapping with Alzheimer's disease clinical and imaging markers.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Basal Ganglia; Brain; Brain Mapping; Carbolines; Cerebral Cortex; Cognitive Dysfunction; Female; Globus Pallidus; Gray Matter; Humans; Iron; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Organ Size; Positron-Emission Tomography; Putamen; Radiopharmaceuticals; Substantia Nigra; Subthalamic Nucleus; tau Proteins; Thiazoles | 2021 |
Hippocampal subregional volume changes in elders classified using positron emission tomography-based Alzheimer's biomarkers of β-amyloid deposition and neurodegeneration.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Atrophy; Biomarkers; Carbon Radioisotopes; Cognitive Dysfunction; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Neuroimaging; Organ Size; Positron-Emission Tomography; Protein Aggregates; Radiopharmaceuticals; Thiazoles; White Matter | 2021 |
Association of Cerebrospinal Fluid Adiponectin Levels With Cerebral Glucose Metabolism In Mild Cognitive Impairment: A Pilot Study.
Topics: Adiponectin; Aged; Amyloid; Aniline Compounds; Brain; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Pilot Projects; Positron-Emission Tomography; Thiazoles | 2020 |
Clinical impact of 11C-Pittsburgh compound-B positron emission tomography in addition to magnetic resonance imaging and single-photon emission computed tomography on diagnosis of mild cognitive impairment to Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2021 |
Test-Retest Variability of Relative Tracer Delivery Rate as Measured by [
Topics: Adult; Aged; Alzheimer Disease; Aniline Compounds; Cerebrovascular Circulation; Cognitive Dysfunction; Female; Gray Matter; Humans; Image Processing, Computer-Assisted; Linear Models; Male; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Thiazoles; Water | 2021 |
Head-to-head comparison of 11C-PiB and 18F-FC119S for Aβ imaging in healthy subjects, mild cognitive impairment patients, and Alzheimer's disease patients.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Brain; Carbon Radioisotopes; Cognitive Dysfunction; Female; Fluorine Radioisotopes; Healthy Volunteers; Humans; Male; Middle Aged; Positron-Emission Tomography; Thiazoles | 2017 |
Chemically treated plasma Aβ is a potential blood-based biomarker for screening cerebral amyloid deposition.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Brain; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Male; Peptide Fragments; Plaque, Amyloid; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Thiazoles | 2017 |
Metabolic network failures in Alzheimer's disease: A biochemical road map.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Aniline Compounds; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Fasting; Female; Humans; Male; Metabolic Diseases; Metabolic Networks and Pathways; Metabolomics; Peptide Fragments; Phosphatidylcholines; Sphingomyelins; tau Proteins; Thiazoles | 2017 |
Memory self-awareness in the preclinical and prodromal stages of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Awareness; Brain; Cognitive Dysfunction; Cost of Illness; Cross-Sectional Studies; Diagnostic Self Evaluation; Disease Progression; Female; Humans; Male; Memory; Mental Status and Dementia Tests; Middle Aged; Positron-Emission Tomography; Prodromal Symptoms; Radiopharmaceuticals; Thiazoles | 2017 |
Regional amyloid burden and lacune in pure subcortical vascular cognitive impairment.
Topics: Aged; Aged, 80 and over; Amyloidogenic Proteins; Aniline Compounds; Brain; Brain Mapping; Cerebral Small Vessel Diseases; Cognition; Cognitive Dysfunction; Dementia, Vascular; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Thiazoles; Tomography, X-Ray Computed | 2017 |
Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Case-Control Studies; Cerebral Cortex; Cognitive Dysfunction; Disease Progression; Encephalitis; Female; Humans; Isoquinolines; Male; Microglia; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles | 2017 |
Functional network integrity presages cognitive decline in preclinical Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Cognitive Dysfunction; Connectome; Disease Progression; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Net; Positron-Emission Tomography; Prodromal Symptoms; Prognosis; Thiazoles | 2017 |
A Cross-Validation of FDG- and Amyloid-PET Biomarkers in Mild Cognitive Impairment for the Risk Prediction to Dementia due to Alzheimer's Disease in a Clinical Setting.
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Dementia; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; ROC Curve; Thiazoles | 2017 |
Cognitive decline and brain amyloid-β accumulation across 3 years in adults with Down syndrome.
Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognition; Cognitive Dysfunction; Down Syndrome; Executive Function; Female; Humans; Male; Memory, Episodic; Middle Aged; Phenanthrolines; Positron-Emission Tomography; Thiazoles; Time Factors | 2017 |
The evaluation of brain perfusion SPECT using an easy Z-score imaging system in the mild cognitive impairment subjects with brain amyloid-β deposition.
Topics: Aged; Aged, 80 and over; Amnesia; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Organotechnetium Compounds; Perfusion Imaging; Positron-Emission Tomography; Sensitivity and Specificity; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2017 |
Microvascular ultrastructural changes precede cognitive impairment in the murine APPswe/PS1dE9 model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Benzothiazoles; Capillaries; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Exploratory Behavior; Intussusception; Kidney Glomerulus; Liver; Male; Memory, Short-Term; Mice, Transgenic; Microvessels; Plaque, Amyloid; Spleen; Thiazoles | 2017 |
Urine AD7c-NTP Predicts Amyloid Deposition and Symptom of Agitation in Patients with Alzheimer's Disease and Mild Cognitive Impairment.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Area Under Curve; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Tissue Proteins; Neuropsychological Tests; Positron-Emission Tomography; Predictive Value of Tests; Psychiatric Status Rating Scales; Radioisotopes; Thiazoles | 2017 |
Whole-body biodistribution and the influence of body activity on brain kinetic analysis of the
Topics: Aged; Aged, 80 and over; Aniline Compounds; Benzothiazoles; Brain; Carbon Radioisotopes; Case-Control Studies; Cognitive Dysfunction; Exercise; Humans; Image Processing, Computer-Assisted; Kinetics; Middle Aged; Phantoms, Imaging; Positron-Emission Tomography; Thiazoles; Tissue Distribution; Whole Body Imaging | 2017 |
Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain; Carbolines; Cognitive Dysfunction; Cross-Sectional Studies; Diagnostic Self Evaluation; Entorhinal Cortex; Female; Frontal Lobe; Humans; Male; Middle Aged; Neocortex; Parietal Lobe; Phenanthrolines; Positron-Emission Tomography; Radiopharmaceuticals; Surveys and Questionnaires; tau Proteins; Tauopathies; Temporal Lobe; Thiazoles | 2017 |
Utility of Molecular and Structural Brain Imaging to Predict Progression from Mild Cognitive Impairment to Dementia.
Topics: Aged; Aged, 80 and over; Aniline Compounds; Apolipoproteins E; Benzothiazoles; Brain; Cognitive Dysfunction; Dementia; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Organ Size; Positron-Emission Tomography; Prognosis; Proportional Hazards Models; Radiopharmaceuticals; Thiazoles | 2017 |
Tau pathology and neurodegeneration contribute to cognitive impairment in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Aphasia, Primary Progressive; Benzothiazoles; Brain; Carbolines; Carbon Radioisotopes; Case-Control Studies; Cognitive Dysfunction; Female; Fluorine Radioisotopes; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Regression Analysis; tau Proteins; Thiazoles | 2017 |
11C-PIB PET image analysis for Alzheimer's diagnosis using weighted voting ensembles.
Topics: Alzheimer Disease; Aniline Compounds; Benzothiazoles; Carbon Radioisotopes; Cognitive Dysfunction; Humans; Positron-Emission Tomography; Thiazoles | 2017 |
Fibre-specific white matter reductions in Alzheimer's disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Brain; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Imaging, Three-Dimensional; Male; Mental Status Schedule; Nerve Fibers; Positron-Emission Tomography; Thiazoles; White Matter | 2018 |
Predicting progression from normal cognition to mild cognitive impairment for individuals at 5 years.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Brain; Cognitive Dysfunction; Cohort Studies; Disease Progression; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Predictive Value of Tests; ROC Curve; tau Proteins; Thiazoles; Time Factors | 2018 |
Tau-negative amnestic dementia masquerading as Alzheimer disease dementia.
Topics: Aged; Aged, 80 and over; Amnesia; Aniline Compounds; Atrophy; Brain; Carbolines; Cognitive Dysfunction; Dementia; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Organ Size; Positron-Emission Tomography; Radiopharmaceuticals; tau Proteins; Thiazoles | 2018 |
Electromagnetic signatures of the preclinical and prodromal stages of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Aniline Compounds; Brain; Brain Mapping; Cognitive Dysfunction; Disease Progression; Female; Humans; Magnetic Resonance Imaging; Magnetoencephalography; Male; Neuropsychological Tests; Positron-Emission Tomography; Prodromal Symptoms; Psychiatric Status Rating Scales; Thiazoles | 2018 |
Heme Oxygenase-1 Activity as a Correlate to Exercise-Mediated Amelioration of Cognitive Decline and Neuropathological Alterations in an Aging Rat Model of Dementia.
Topics: Aging; Amyloid; Aniline Compounds; Animals; Brain; Cerebral Amyloid Angiopathy; Cognitive Dysfunction; Dementia; Disease Models, Animal; Female; Heme Oxygenase-1; Male; Maze Learning; Physical Conditioning, Animal; Positron-Emission Tomography; Rats, Wistar; Spatial Memory; Thiazoles | 2018 |
Prevalence and Outcomes of Amyloid Positivity Among Persons Without Dementia in a Longitudinal, Population-Based Setting.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Asymptomatic Diseases; Brain; Case-Control Studies; Cognitive Dysfunction; Female; Humans; Longitudinal Studies; Male; Middle Aged; Plaque, Amyloid; Positron-Emission Tomography; Prevalence; Proportional Hazards Models; Prospective Studies; Thiazoles; United States | 2018 |
The correlation between striatal and cortical binding ratio of
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Cerebral Cortex; Cognitive Dysfunction; Corpus Striatum; Female; Frontotemporal Lobar Degeneration; Humans; Lewy Body Disease; Male; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Retrospective Studies; Thiazoles | 2018 |
Adaptive template generation for amyloid PET using a deep learning approach.
Topics: Algorithms; Alzheimer Disease; Amyloid; Aniline Compounds; Benzothiazoles; Brain; Carbon Radioisotopes; Cognitive Dysfunction; Deep Learning; Female; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Radiopharmaceuticals; Supervised Machine Learning; Thiazoles | 2018 |
Mediterranean Diet, Its Components, and Amyloid Imaging Biomarkers.
Topics: Aged; Aged, 80 and over; Amyloid; Aniline Compounds; Brain; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Dementia; Diet, Mediterranean; Female; Humans; Male; Neuropsychological Tests; Positron-Emission Tomography; Prospective Studies; Psychiatric Status Rating Scales; Surveys and Questionnaires; Thiazoles | 2018 |
Amyloid deposition and CBF patterns predict conversion of mild cognitive impairment to dementia.
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Brain; Cognitive Dysfunction; Disease Progression; Female; Follow-Up Studies; Humans; Male; Neuropsychological Tests; Perfusion Imaging; Phenanthrolines; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Retrospective Studies; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2018 |
Vascular Effects on Depressive Symptoms in Cognitive Impairment.
Topics: Aged; Amyloid; Aniline Compounds; Brain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Depression; Diffusion Tensor Imaging; Female; Humans; Male; Organ Size; Phenanthrolines; Positron-Emission Tomography; Prospective Studies; Psychiatric Status Rating Scales; Radiopharmaceuticals; Thiazoles | 2018 |
Incident cognitive impairment: longitudinal changes in molecular, structural and cognitive biomarkers.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Biomarkers; Cognitive Dysfunction; Female; Genotype; Humans; Incidence; Kaplan-Meier Estimate; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Peptide Fragments; Positron-Emission Tomography; Psychometrics; Thiazoles | 2018 |
Brain Structural and Amyloid Correlates of Recovery From Semantic Interference in Cognitively Normal Individuals With or Without Family History of Late-Onset Alzheimer's Disease.
Topics: Adult; Age of Onset; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognitive Dysfunction; Cross-Sectional Studies; Female; Genetic Predisposition to Disease; Humans; Magnetic Resonance Imaging; Male; Mental Recall; Positron-Emission Tomography; Thiazoles; Young Adult | 2019 |
Distinct amyloid distribution patterns in amyloid positive subcortical vascular cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Amyloidogenic Proteins; Aniline Compounds; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Occipital Lobe; Positron-Emission Tomography; Thiazoles | 2018 |
The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease.
Topics: Aged; alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aniline Compounds; Apolipoproteins E; Brain; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Peptide Fragments; Positron-Emission Tomography; ROC Curve; Statistics, Nonparametric; tau Proteins; Thiazoles | 2018 |
Plasma Aβ42/40 Ratio Detects Early Stages of Alzheimer's Disease and Correlates with CSF and Neuroimaging Biomarkers in the AB255 Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Biomarkers; Case-Control Studies; Cognitive Dysfunction; Cross-Sectional Studies; Early Diagnosis; Female; Fluorodeoxyglucose F18; Genotype; Humans; Male; Neuroimaging; Peptide Fragments; Phosphorylation; Plaque, Amyloid; Positron-Emission Tomography; Prodromal Symptoms; tau Proteins; Thiazoles | 2019 |
Early after Administration [11C]PiB PET Images Correlate with Cognitive Dysfunction Measured by the CERAD Test Battery.
Topics: Aged; Aniline Compounds; Carbon Radioisotopes; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Retrospective Studies; Thiazoles; Time Factors | 2019 |
Relative cerebral flow from dynamic PIB scans as an alternative for FDG scans in Alzheimer's disease PET studies.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Brain; Carbon Radioisotopes; Case-Control Studies; Cerebrovascular Circulation; Cognitive Dysfunction; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2019 |
Regional Tau Correlates of Instrumental Activities of Daily Living and Apathy in Mild Cognitive Impairment and Alzheimer's Disease Dementia.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apathy; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Surveys and Questionnaires; tau Proteins; Thiazoles | 2019 |
Dynamic
Topics: Adult; Aged; Algorithms; Alzheimer Disease; Aniline Compounds; Area Under Curve; Brain; Case-Control Studies; Cerebrospinal Fluid; Cognitive Dysfunction; Databases, Factual; Female; Homeostasis; Humans; Kinetics; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Thiazoles | 2019 |
A 5-year longitudinal evaluation in patients with mild cognitive impairment by 11C-PIB PET/CT: a visual analysis.
Topics: Aged; Aniline Compounds; Benzothiazoles; Cognitive Dysfunction; Female; Humans; Image Processing, Computer-Assisted; Longitudinal Studies; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Thiazoles | 2019 |
Alzheimer disease biomarkers may aid in the prognosis of MCI cases initially reverted to normal.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Brain; Cognitive Dysfunction; Dementia; Disease Progression; Ethylene Glycols; Female; Humans; Male; Middle Aged; Peptide Fragments; Plaque, Amyloid; Positron-Emission Tomography; Prognosis; Recurrence; Remission, Spontaneous; Risk Assessment; tau Proteins; Thiazoles | 2019 |
Acutely elevated O-GlcNAcylation suppresses hippocampal activity by modulating both intrinsic and synaptic excitability factors.
Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; CA1 Region, Hippocampal; Cells, Cultured; Cognitive Dysfunction; Excitatory Postsynaptic Potentials; Humans; Intravital Microscopy; Male; Memory Disorders; Mice; Models, Animal; N-Acetylglucosaminyltransferases; Neurons; Optical Imaging; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Primary Cell Culture; Protein Processing, Post-Translational; Pyrans; Rats; Receptors, AMPA; Synapses; Thiazoles; Voltage-Gated Sodium Channels | 2019 |
Biopathological Significance of Early-Phase Amyloid Imaging in the Spectrum of Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Carbon Radioisotopes; Cognitive Dysfunction; Cross-Sectional Studies; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Positron-Emission Tomography; Thiazoles | 2019 |
Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures.
Topics: Aged; Aniline Compounds; Attention; Brain; Cognition; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Male; Neurofilament Proteins; Neuropsychological Tests; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2019 |
Cognitive reserve and clinical progression in Alzheimer disease: A paradoxical relationship.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Case-Control Studies; Cognitive Dysfunction; Cognitive Reserve; Contrast Media; Disease Progression; Ethylene Glycols; Executive Function; Female; Gray Matter; Humans; Male; Memory; Middle Aged; Organ Size; Peptide Fragments; Thiazoles; White Matter | 2019 |
Brain Amyloid PET Tracer Delivery is Related to White Matter Integrity in Patients with Mild Cognitive Impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Brain; Cerebrovascular Circulation; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Plaque, Amyloid; Positron-Emission Tomography; Thiazoles; White Matter | 2019 |
Determining clinically meaningful decline in preclinical Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Asymptomatic Diseases; Benzothiazoles; Brain; Cognitive Dysfunction; Contrast Media; Disease Progression; Ethylene Glycols; Female; Humans; Male; Mental Recall; Mental Status and Dementia Tests; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles; Time Factors; Trail Making Test | 2019 |
White matter hyperintensities and cerebral amyloidosis: necessary and sufficient for clinical expression of Alzheimer disease?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloidosis; Aniline Compounds; Brain Mapping; Cerebral Cortex; Cognitive Dysfunction; Databases, Factual; Female; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Positron-Emission Tomography; Thiazoles | 2013 |
Association of plasma and cortical amyloid beta is modulated by APOE ε4 status.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Brain; Cerebral Cortex; Cognitive Dysfunction; Female; Humans; Male; Neuropsychological Tests; Peptide Fragments; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2014 |
Three-month stability of the CogState brief battery in healthy older adults, mild cognitive impairment, and Alzheimer's disease: results from the Australian Imaging, Biomarkers, and Lifestyle-rate of change substudy (AIBL-ROCS).
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Aniline Compounds; Association Learning; Australia; Case-Control Studies; Cognitive Dysfunction; Disease Progression; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Positron-Emission Tomography; Reaction Time; Reproducibility of Results; Thiazoles; Time Factors | 2013 |
Assessing mild cognitive impairment with amyloid and dopamine terminal molecular imaging.
Topics: Aged; Amyloid; Aniline Compounds; Benzothiazoles; Cognitive Dysfunction; Cohort Studies; Dopamine; Female; Follow-Up Studies; Humans; Male; Positron-Emission Tomography; Prognosis; Tetrabenazine; Thiazoles | 2013 |
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognitive Dysfunction; Cohort Studies; Dextrans; Female; Genetic Association Studies; Genotype; HLA-D Antigens; Humans; Male; Microglia; Middle Aged; Monocytes; Peptide Fragments; Plaque, Amyloid; Polymorphism, Genetic; Radionuclide Imaging; Sialic Acid Binding Ig-like Lectin 3; Thiazoles; Young Adult | 2013 |
Diagnosed mild cognitive impairment due to Alzheimer's disease with PET biomarkers of beta amyloid and neuronal dysfunction.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cerebral Cortex; Cognitive Dysfunction; Disease Progression; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Sensitivity and Specificity; Thiazoles | 2013 |
[11C]PIB, [18F]FDG and MR imaging in patients with mild cognitive impairment.
Topics: Aged; Aniline Compounds; Benzothiazoles; Cerebral Cortex; Cognitive Dysfunction; Disease Progression; Female; Fluorodeoxyglucose F18; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Thiazoles | 2013 |
Longitudinal amyloid imaging using 11C-PiB: methodologic considerations.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Biomarkers; Brain; Cognitive Dysfunction; Female; Humans; Longitudinal Studies; Male; Molecular Imaging; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Thiazoles; Tissue Distribution | 2013 |
Comparison of neuroimaging modalities for the prediction of conversion from mild cognitive impairment to Alzheimer's dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Apolipoproteins E; Brain; Cognitive Dysfunction; Cohort Studies; Disease Progression; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Forecasting; Genotype; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Positron-Emission Tomography; Radiopharmaceuticals; Sensitivity and Specificity; Temporal Lobe; Thiazoles | 2014 |
Five-year follow-up of 11C-PIB uptake in Alzheimer's disease and MCI.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Case-Control Studies; Cognitive Dysfunction; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2014 |
Hippocampal and cortical atrophy in amyloid-negative mild cognitive impairments: comparison with amyloid-positive mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Atrophy; Cerebral Cortex; Cognitive Dysfunction; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Risk; Thiazoles | 2014 |
Imaging of amyloid deposition in human brain using positron emission tomography and [18F]FACT: comparison with [11C]PIB.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Benzoxazoles; Brain; Case-Control Studies; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Plaque, Amyloid; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles; Tissue Distribution | 2014 |
Apathy is associated with increased amyloid burden in mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Amyloid; Aniline Compounds; Apathy; Cerebral Cortex; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Functional Neuroimaging; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2013 |
Analysis of early phase [11C]BF-227 PET, and its application for anatomical standardization of late-phase images for 3D-SSP analysis.
Topics: Aged; Alzheimer Disease; Benzoxazoles; Brain; Carbon Radioisotopes; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Imaging, Three-Dimensional; Male; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Thiazoles | 2014 |
Cortical thickness and hippocampal shape in pure vascular mild cognitive impairment and dementia of subcortical type.
Topics: Aged; Aniline Compounds; Cerebral Cortex; Cognitive Dysfunction; Dementia; Dementia, Vascular; Female; Hippocampus; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles | 2014 |
Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Choline O-Acetyltransferase; Cognitive Dysfunction; Female; Humans; In Vitro Techniques; Male; Mental Status Schedule; Nerve Growth Factor; Neuropil Threads; Parietal Lobe; Prodromal Symptoms; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Statistics, Nonparametric; Thiazoles; Tritium | 2015 |
Alzheimer's disease-like pattern of (18)F-FDG uptake during a hyperglycemic state and negative (11)C-PiB binding in a patient with mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Hyperglycemia; Male; Middle Aged; Positron-Emission Tomography; Thiazoles | 2014 |
[Alzheimer dementia: why therapy comes too late].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain; Cognitive Dysfunction; Disease Progression; Humans; Positron-Emission Tomography; Thiazoles | 2014 |
Imaging discrepancies between magnetic resonance imaging and brain perfusion single-photon emission computed tomography in the diagnosis of Alzheimer's disease, and verification with amyloid positron emission tomography.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Ambulatory Care Facilities; Amyloid; Brain; Cognitive Dysfunction; Female; Geriatric Assessment; Humans; Magnetic Resonance Imaging; Male; Neuroimaging; Regional Blood Flow; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2014 |
Disrupted Intrinsic Networks Link Amyloid-β Pathology and Impaired Cognition in Prodromal Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Attention; Brain Mapping; Cognition; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles | 2015 |
Plasma Aβ but not tau is related to brain PiB retention in early Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain; Chi-Square Distribution; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments; Psychiatric Status Rating Scales; Radionuclide Imaging; Regression Analysis; tau Proteins; Thiazoles | 2014 |
Cortical hypermetabolism in MCI subjects: a compensatory mechanism?
Topics: Aged; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Blood Glucose; Cerebral Cortex; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2015 |
Pitfalls of voxel-based amyloid PET analyses for diagnosis of Alzheimer's disease: artifacts due to non-specific uptake in the white matter and the skull.
Topics: Aged; Alzheimer Disease; Amyloid; Artifacts; Benzoxazoles; Cognitive Dysfunction; Dementia; Demography; Female; Humans; Male; Positron-Emission Tomography; Skull; Thiazoles; White Matter | 2014 |
Relationships between performance on the Cogstate Brief Battery, neurodegeneration, and Aβ accumulation in cognitively normal older adults and adults with MCI.
Topics: Aged; Aged, 80 and over; Aging; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Atrophy; Carbon Isotopes; Cognitive Dysfunction; Female; Hippocampus; Humans; Linear Models; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Middle Aged; Nerve Degeneration; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles; Time Factors | 2015 |
Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures.
Topics: Aged; Algorithms; Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Aniline Compounds; Biomarkers; Brain; Cognition; Cognitive Dysfunction; Cohort Studies; Databases, Factual; Disease Progression; Female; Humans; Male; Neuropsychological Tests; Pattern Recognition, Automated; Peptide Fragments; Positron-Emission Tomography; Sensitivity and Specificity; Thiazoles | 2015 |
Concordance and Diagnostic Accuracy of [11C]PIB PET and Cerebrospinal Fluid Biomarkers in a Sample of Patients with Mild Cognitive Impairment and Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Biomarkers; Brain; Cognitive Dysfunction; Cohort Studies; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Logistic Models; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments; Phosphorylation; Positron-Emission Tomography; Radiopharmaceuticals; tau Proteins; Thiazoles | 2015 |
Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner.
Topics: Aged; Aged, 80 and over; Aging; Alleles; Amyloidogenic Proteins; Aniline Compounds; Apolipoprotein E4; Brain; Cognition; Cognitive Dysfunction; Female; Genotype; Humans; Male; Middle Aged; Regional Blood Flow; Thiazoles | 2015 |
Concordance between 11C-PIB-PET and clinical diagnosis in a memory clinic.
Topics: Aged; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Aniline Compounds; Aphasia, Primary Progressive; Atrophy; Benzothiazoles; Cerebral Amyloid Angiopathy; Cerebral Cortex; Cognitive Dysfunction; Dementia; Female; Frontotemporal Lobar Degeneration; Humans; Male; Middle Aged; Positron-Emission Tomography; Retrospective Studies; Thiazoles | 2015 |
Connectivity analysis of normal and mild cognitive impairment patients based on FDG and PiB-PET images.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Brain; Case-Control Studies; Cognitive Dysfunction; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Male; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2015 |
Amyloid Beta-Weighted Cortical Thickness: A New Imaging Biomarker in Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Brain Mapping; Cerebral Cortex; Cognitive Dysfunction; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neurofibrillary Tangles; Positron-Emission Tomography; Thiazoles | 2015 |
Clinical impact of (11)C-Pittsburgh compound-B positron emission tomography carried out in addition to magnetic resonance imaging and single-photon emission computed tomography on the diagnosis of Alzheimer's disease in patients with dementia and mild cog
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Benzothiazoles; Brain; Carbon Radioisotopes; Cognitive Dysfunction; Dementia; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Thiazoles; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2015 |
Combination of dynamic (11)C-PIB PET and structural MRI improves diagnosis of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Atrophy; Cognitive Dysfunction; Female; Gray Matter; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Thiazoles | 2015 |
Amyloid PET in European and North American cohorts; and exploring age as a limit to clinical use of amyloid imaging.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Brain; Cognitive Dysfunction; Cohort Studies; Ethylene Glycols; Europe; Female; Humans; Male; Middle Aged; Molecular Imaging; North America; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Sex Characteristics; Thiazoles | 2015 |
Amyloid-Independent Amnestic Mild Cognitive Impairment and Serum Apolipoprotein A1 Levels.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Amyloid; Aniline Compounds; Apolipoprotein A-I; Atrophy; Brain; Brain Mapping; Cognitive Dysfunction; Cross-Sectional Studies; Disease Progression; Female; Follow-Up Studies; Humans; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2016 |
Amyloid Imaging With 11C-PIB in Patients With Cognitive Impairment in a Clinical Setting: A Visual and Semiquantitative Analysis.
Topics: Aged; Amyloid; Aniline Compounds; Benzothiazoles; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Thiazoles; Tomography, X-Ray Computed | 2016 |
Performance of 11C-Pittsburgh Compound B PET Binding Potential Images in the Detection of Amyloid Deposits on Equivocal Static Images.
Topics: Aged; Aged, 80 and over; Aniline Compounds; Cerebral Cortex; Cognition Disorders; Cognitive Dysfunction; Female; Gray Matter; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Plaque, Amyloid; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles; White Matter | 2015 |
Long-Term Interrelationship between Brain Metabolism and Amyloid Deposition in Mild Cognitive Impairment.
Topics: Aged; Amyloid; Aniline Compounds; Brain; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted; Longitudinal Studies; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Positron-Emission Tomography; Thiazoles | 2015 |
Role of β-Amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloidosis; Aniline Compounds; Cognitive Dysfunction; Cohort Studies; Disease Progression; Female; Fluorodeoxyglucose F18; Gray Matter; Humans; Male; Neurodegenerative Diseases; Positron-Emission Tomography; Thiazoles | 2015 |
Tau positron emission tomographic imaging in aging and early Alzheimer disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Carbolines; Cerebral Cortex; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Positron-Emission Tomography; tau Proteins; Temporal Lobe; Thiazoles | 2016 |
Visual Versus Fully Automated Analyses of 18F-FDG and Amyloid PET for Prediction of Dementia Due to Alzheimer Disease in Mild Cognitive Impairment.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Cognitive Dysfunction; Dementia; Disease Progression; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Observer Variation; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Thiazoles | 2016 |
PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies.
Topics: Alzheimer Disease; Aniline Compounds; Brain; Carbolines; Cocaine; Cognitive Dysfunction; Cross-Sectional Studies; Diagnosis, Differential; Lewy Body Disease; Magnetic Resonance Imaging; Neuropsychological Tests; Parkinson Disease; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Survival Analysis; Thiazoles | 2016 |
Comparison of Early-Phase 11C-Deuterium-l-Deprenyl and 11C-Pittsburgh Compound B PET for Assessing Brain Perfusion in Alzheimer Disease.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Cerebellum; Cerebrovascular Circulation; Cognitive Dysfunction; Deuterium; Diagnosis, Differential; Female; Fluorodeoxyglucose F18; Gliosis; Gray Matter; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Perfusion; Pons; Positron-Emission Tomography; Radiopharmaceuticals; Selegiline; Thiazoles | 2016 |
Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid; Aniline Compounds; Apolipoproteins E; Benzothiazoles; Brain; Carbolines; Case-Control Studies; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Neuroimaging; Neuropsychological Tests; Positron-Emission Tomography; tau Proteins; Thiazoles | 2016 |
Comparability of [
Topics: Alzheimer Disease; Aniline Compounds; Brain; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Positron-Emission Tomography; Quinolines; Radiopharmaceuticals; Thiazoles | 2017 |
Relative impact of amyloid-β, lacunes, and downstream imaging markers on cognitive trajectories.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Cerebral Cortex; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Executive Function; Female; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory Disorders; Positron-Emission Tomography; Stroke, Lacunar; Thiazoles | 2016 |
Diagnostic role of 11C-Pittsburgh compound B retention patterns and glucose metabolism by fluorine-18-fluorodeoxyglucose PET/CT in amnestic and nonamnestic mild cognitive impairment patients.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Aniline Compounds; Brain; Carbon Radioisotopes; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Thiazoles | 2016 |
PiB-PET Imaging-Based Serum Proteome Profiles Predict Mild Cognitive Impairment and Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Blood Proteins; Chromatography, Liquid; Cognitive Dysfunction; Disease Progression; Enzyme-Linked Immunosorbent Assay; Factor XIII; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Peptides; Positron-Emission Tomography; Proprotein Convertase 9; Tandem Mass Spectrometry; Thiazoles | 2016 |
Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Dementia; Enzyme-Linked Immunosorbent Assay; Europe; Female; Humans; Male; Mass Spectrometry; Middle Aged; Peptide Fragments; Positron-Emission Tomography; Thiazoles | 2016 |
Decreased hippocampal metabolism in high-amyloid mild cognitive impairment.
Topics: Aged; Amyloid; Aniline Compounds; Atrophy; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Hippocampus; Humans; Image Processing, Computer-Assisted; Male; Positron-Emission Tomography; Thiazoles | 2016 |
Heterogeneity in Suspected Non-Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Female; Humans; Longitudinal Studies; Male; Middle Aged; tau Proteins; Tauopathies; Thiazoles | 2016 |
Optimizing PiB-PET SUVR change-over-time measurement by a large-scale analysis of longitudinal reliability, plausibility, separability, and correlation with MMSE.
Topics: Adult; Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognitive Dysfunction; Dementia; Female; Humans; Longitudinal Studies; Male; Middle Aged; Positron-Emission Tomography; Reproducibility of Results; Thiazoles | 2017 |
Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Carbolines; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Lewy Body Disease; Magnetic Resonance Imaging; Male; Middle Aged; Neocortex; Parkinson Disease; Positron-Emission Tomography; tau Proteins; Thiazoles | 2016 |
Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated amyloid β.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Asymptomatic Diseases; Cognitive Dysfunction; Cohort Studies; Disease Progression; Female; Humans; Male; Neuropsychological Tests; Positron-Emission Tomography; Psychiatric Status Rating Scales; Thiazoles | 2017 |
Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimer's disease.
Topics: Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Dendritic Spines; Female; Humans; Male; Microfilament Proteins; Nerve Tissue Proteins; Parietal Lobe; Plaque, Amyloid; Thiazoles | 2017 |
Relationship between cytokine levels in the cerebrospinal fluid and 11C-Pittsburgh compound B retention in patients with mild cognitive impairment.
Topics: Aged; Aniline Compounds; Cognitive Dysfunction; Cytokines; Female; Humans; Male; Thiazoles | 2017 |
Cognitive Composites Domain Scores Related to Neuroimaging Biomarkers within Probable-Amnestic Mild Cognitive Impairment-Storage Subtype.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Brain; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Mental Recall; Neuroimaging; Neuropsychological Tests; Organ Size; Positron-Emission Tomography; Prodromal Symptoms; Radiopharmaceuticals; Survival Analysis; Thiazoles | 2017 |
Amyloid-β Deposition and Long-Term Progression in Mild Cognitive Impairment due to Alzheimer's Disease Defined with Amyloid PET Imaging.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Cognitive Dysfunction; Disease Progression; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Positron-Emission Tomography; Thiazoles | 2017 |
Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain; Carbon Radioisotopes; Cognition; Cognitive Dysfunction; Disease Progression; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Follow-Up Studies; Glucose; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles; Time Factors | 2012 |
Investigation of matrix metalloproteinases, MMP-2 and MMP-9, in plasma reveals a decrease of MMP-2 in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuropsychological Tests; Thiazoles | 2011 |
Amyloid imaging: liberal or conservative? Let the data decide.
Topics: Alzheimer Disease; Aniline Compounds; Benzothiazoles; Cerebral Cortex; Cognitive Dysfunction; Dementia; Ethylene Glycols; Female; Fluorine Radioisotopes; Humans; Male; Plaque, Amyloid; Positron-Emission Tomography; Thiazoles | 2011 |
Brain amyloid imaging.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain; Cognitive Dysfunction; Education, Medical; Fluorine Radioisotopes; Humans; Image Interpretation, Computer-Assisted; Ligands; Molecular Imaging; Nuclear Medicine; Positron-Emission Tomography; Radiopharmaceuticals; Sensitivity and Specificity; Thiazoles | 2011 |
[Current amyloid imaging].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Cognitive Dysfunction; Humans; Middle Aged; Positron-Emission Tomography; Thiazoles | 2010 |
CSF biomarker and PIB-PET-derived beta-amyloid signature predicts metabolic, gray matter, and cognitive changes in nondemented subjects.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Brain; Cognitive Dysfunction; Early Diagnosis; Humans; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2012 |
Coronary risk correlates with cerebral amyloid deposition.
Topics: Aged; Aged, 80 and over; Amyloid; Aniline Compounds; Apolipoproteins E; Brain Mapping; Carbon Radioisotopes; Carotid Intima-Media Thickness; Cerebral Cortex; Cognitive Dysfunction; Coronary Disease; Female; Humans; Lipoproteins; Longitudinal Studies; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Positron-Emission Tomography; Predictive Value of Tests; Risk; Thiazoles | 2012 |
Alzheimer disease biomarkers are associated with body mass index.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Body Mass Index; Cognitive Dysfunction; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Overweight; Positron-Emission Tomography; tau Proteins; Thiazoles | 2011 |
The use of PIB-PET as a dual pathological and functional biomarker in AD.
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Benzothiazoles; Biomarkers; Carbon Radioisotopes; Cognitive Dysfunction; Deoxyglucose; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Parietal Lobe; Positron-Emission Tomography; Regional Blood Flow; Thiazoles | 2012 |
Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain; Case-Control Studies; Cognitive Dysfunction; Deuterium; Female; Fluorodeoxyglucose F18; Gliosis; Humans; Male; Middle Aged; Monoamine Oxidase; Neuropsychological Tests; Positron-Emission Tomography; Radioactive Tracers; Retrospective Studies; Selegiline; Thiazoles | 2012 |
Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid deposition.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Atrophy; Brain Mapping; Cerebellum; Cerebral Cortex; Cognition; Cognitive Dysfunction; Disease Progression; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neocortex; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2012 |
Regional dynamics of amyloid-β deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: a voxelwise PiB-PET longitudinal study.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain Mapping; Carbon Radioisotopes; Case-Control Studies; Cognitive Dysfunction; Disease Progression; Female; Humans; Longitudinal Studies; Male; Neocortex; Neuropsychological Tests; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2012 |
Maternal family history is associated with Alzheimer's disease biomarkers.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Family Health; Female; Humans; Male; Middle Aged; Mothers; Positron-Emission Tomography; Thiazoles | 2012 |
Brain amyloid and cognition in Lewy body diseases.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Antiparkinson Agents; Apolipoprotein E3; Cognition; Cognitive Dysfunction; Female; Genotype; Humans; Levodopa; Lewy Body Disease; Male; Neurologic Examination; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Thiazoles | 2012 |
Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment.
Topics: Aging; Allosteric Regulation; Animals; Carboxylic Acids; Cognition; Cognitive Dysfunction; GABA-A Receptor Agonists; Hippocampus; Infusions, Intraventricular; Injections, Intraperitoneal; Male; Memory; Memory Disorders; Molecular Targeted Therapy; Neurons; Nootropic Agents; Pyridazines; Rats; Rats, Long-Evans; Receptors, GABA-A; Specific Pathogen-Free Organisms; Synaptic Transmission; Thiazoles; Thiophenes | 2013 |
4-Hydroxyhexenal (HHE) impairs glutamate transport in astrocyte cultures.
Topics: Aged, 80 and over; Aldehydes; Alzheimer Disease; Animals; Astrocytes; Biological Transport, Active; Blotting, Western; Brain Chemistry; Cells, Cultured; Cognitive Dysfunction; Coloring Agents; Excitatory Amino Acid Transporter 2; Female; Glutamate Plasma Membrane Transport Proteins; Glutamates; Humans; Immunoprecipitation; Lipid Peroxidation; Male; Parahippocampal Gyrus; Rats; Tetrazolium Salts; Thiazoles | 2012 |
Postmortem Pittsburgh Compound B (PiB) binding increases with Alzheimer's disease progression.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aniline Compounds; Brain; Cognitive Dysfunction; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Frontotemporal Dementia; Humans; Male; Neuropsychological Tests; Organ Size; Positron-Emission Tomography; Thiazoles | 2012 |
Cognitive decline and amyloid accumulation in patients with mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Caudate Nucleus; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Progression; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Neuropsychological Tests; Positron-Emission Tomography; Psychometrics; Radiopharmaceuticals; Temporal Lobe; Thiazoles | 2012 |
Binary classification of ¹⁸F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI.
Topics: Aged; Algorithms; Alzheimer Disease; Aniline Compounds; Artificial Intelligence; Benzothiazoles; Cognitive Dysfunction; Diagnosis, Differential; Female; Fluorine Radioisotopes; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Observer Variation; Pattern Recognition, Automated; Positron-Emission Tomography; Reproducibility of Results; Sensitivity and Specificity; Thiazoles | 2013 |
The usefulness of amyloid imaging in predicting the clinical outcome after two years in subjects with mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Apolipoprotein E4; Benzothiazoles; Cognitive Dysfunction; Dementia; Disease Progression; Female; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Outcome Assessment, Health Care; Positron-Emission Tomography; Predictive Value of Tests; Thiazoles | 2013 |
Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Cognitive Dysfunction; Cohort Studies; Gonadotropins; Humans; Linear Models; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Peptide Fragments; Positron-Emission Tomography; Psychiatric Status Rating Scales; Risk Factors; Statistics, Nonparametric; Testosterone; Thiazoles | 2014 |
Amyloid and its association with default network integrity in Alzheimer's disease.
Topics: Aged; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognitive Dysfunction; Female; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Net; Positron-Emission Tomography; Thiazoles | 2014 |
Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia.
Topics: Aged; Amyloid; Aniline Compounds; Apolipoprotein E4; Biomarkers; Carbon Radioisotopes; Cognitive Dysfunction; Dementia; Disease Progression; Female; Functional Neuroimaging; Humans; Male; Neuropsychological Tests; Parietal Lobe; Parkinson Disease; Positron-Emission Tomography; Prospective Studies; Thiazoles | 2013 |
Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET.
Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Carbon Radioisotopes; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Thiazoles | 2013 |
The aging brain and cognition: contribution of vascular injury and aβ to mild cognitive dysfunction.
Topics: Aged; Aged, 80 and over; Aging; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Brain Infarction; Cognitive Dysfunction; Cross-Sectional Studies; Executive Function; Female; Humans; Magnetic Resonance Imaging; Male; Memory; Mental Status Schedule; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles; Vascular System Injuries | 2013 |