thiazoles has been researched along with Cocaine Abuse in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 14 (53.85) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Gobin, CM; Hámor, PU; Schwendt, M | 1 |
| Hadad, NA; Hiller, H; Knackstedt, LA; Krause, EG; Namba, MD; Schwendt, M; Shallcross, J; Wu, L | 1 |
| Knackstedt, LA; Schwendt, M; Trantham-Davidson, HL | 1 |
| Baldaia, MA; Berro, LF; Frussa-Filho, R; Hollais, AW; Longo, BM; Marinho, EA; Oliveira-Lima, AJ; Santos, R; Wuo-Silva, R | 1 |
| Arreola, AC; Kimmey, BA; Pierce, RC; Schmidt, HD | 1 |
| Scheyer, AF; Tseng, KY; Wolf, ME | 1 |
| Kim, JH; Lawrence, AJ; Perry, CJ; Reed, F; Zbukvic, IC | 1 |
| Alvarez, Jdo N; Carvalho, Rde C; Frussa-Filho, R; Fukushiro, DF; Ribeiro, LT; Ricardo, VP | 1 |
| Heard, K; Krier, S; Zahniser, NR | 1 |
| Anderson, SM; Famous, KR; Kumaresan, V; Pierce, RC; Schmidt, HD; Yee, J; Yuan, M | 1 |
| Hao, Y; Martin-Fardon, R; Weiss, F | 1 |
| Martin-Fardon, R; Weiss, F | 1 |
| Kalivas, PW; Knackstedt, L; Moussawi, K; Shen, H; Wang, X | 1 |
| Erdur, B; Ergin, A; Kortunay, S; Yuksel, A | 1 |
| Davidson, C; Ellinwood, EH; King, GR; Lee, TH; Yu, GZ | 1 |
| Dew, RE; Hughes, D | 1 |
| Bloch, DA; Ciraulo, AM; Ciraulo, DA; Elkashef, A; Knapp, CM; Leiderman, DB; LoCastro, J; Montgomery, MA; Sarid-Segal, O | 1 |
| Cleveland, NJ; Dewitt, CD; Heard, K | 1 |
| Ciraulo, DA; Hennen, J; Jensen, JE; Ke, Y; Knapp, C; Kwak, T; Meyer, AA; Nassar, LE; Renshaw, PF; Sarid-Segal, O; Streeter, CC | 1 |
| Davis, J; Goeders, NE; Grajkowska, E; Iso, Y; Johnson, KM; Kozikowski, AP; Roth, BL; Sanker, S; Tueckmantel, W; Wroblewski, JT | 1 |
| Bespalov, AY; Danysz, W; Dravolina, OA | 1 |
| Feng, MJ; Yan, QS; Yan, SE | 1 |
| Cleveland, NR; Heard, K; Krier, S | 1 |
| Hoffman, RS; Manini, AF; Pearl-Davis, MS; Wu, S | 1 |
| Fishback, JA; Green, AM; Kaushal, N; Matsumoto, RR; McCurdy, CR; Mésangeau, C; Narayanan, S; Poupaert, JH; Shaikh, J; Viard, E; Xu, YT | 1 |
| Fredman, SJ; Rosenbaum, JF | 1 |
2 trial(s) available for thiazoles and Cocaine Abuse
| Article | Year |
|---|---|
Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence.
Topics: Adolescent; Adult; Antidepressive Agents; Benzothiazoles; Cocaine-Related Disorders; Cyclohexanols; Dopamine Agonists; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Paroxetine; Pentoxifylline; Phosphodiesterase Inhibitors; Pramipexole; Riluzole; Selective Serotonin Reuptake Inhibitors; Thiazoles; Venlafaxine Hydrochloride | 2005 |
Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment.
Topics: Adult; Antidepressive Agents, Second-Generation; Antioxidants; Benzothiazoles; Cocaine-Related Disorders; Cyclohexanols; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nicotine; Pramipexole; Prefrontal Cortex; Protons; Retrospective Studies; Thiazoles; Time Factors; Venlafaxine Hydrochloride | 2005 |
24 other study(ies) available for thiazoles and Cocaine Abuse
| Article | Year |
|---|---|
The role of glutamate mGlu5 and adenosine A2a receptor interactions in regulating working memory performance and persistent cocaine seeking in rats.
Topics: Adenosine A2 Receptor Antagonists; Animals; Cocaine-Related Disorders; Conditioning, Operant; Drug-Seeking Behavior; Male; Memory, Short-Term; Motor Activity; Piperidines; Psychomotor Performance; Purines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Recurrence; Self Administration; Thiazoles | 2020 |
A novel rat model of comorbid PTSD and addiction reveals intersections between stress susceptibility and enhanced cocaine seeking with a role for mGlu5 receptors.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Comorbidity; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Fear; Male; Phenotype; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Resilience, Psychological; Stress Disorders, Post-Traumatic; Stress, Psychological; Thiazoles | 2018 |
The role of ventral and dorsal striatum mGluR5 in relapse to cocaine-seeking and extinction learning.
Topics: Allosteric Regulation; Analysis of Variance; Animals; Basal Ganglia; Biotinylation; Blotting, Western; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electrophysiological Phenomena; Extinction, Psychological; Infusions, Intravenous; Locomotion; Long-Term Synaptic Depression; Male; Microinjections; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Recurrence; Self Administration; Sucrose; Thiazoles | 2014 |
Selective action of an atypical neuroleptic on the mechanisms related to the development of cocaine addiction: a pre-clinical behavioural study.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Male; Mice; Motor Activity; Piperazines; Quinolones; Thiazoles | 2014 |
Group I metabotropic glutamate receptor-mediated activation of PKC gamma in the nucleus accumbens core promotes the reinstatement of cocaine seeking.
Topics: Animals; Benzimidazoles; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Nucleus Accumbens; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Thiazoles | 2015 |
A protein synthesis-dependent mechanism sustains calcium-permeable AMPA receptor transmission in nucleus accumbens synapses during withdrawal from cocaine self-administration.
Topics: Animals; Benzoates; Calcium; Cocaine-Related Disorders; Cycloheximide; Excitatory Amino Acid Antagonists; Glycine; Male; Methoxyhydroxyphenylglycol; Nucleus Accumbens; Patch-Clamp Techniques; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Substance Withdrawal Syndrome; Synapses; Synaptic Transmission; Thiazoles; Ventral Tegmental Area | 2014 |
The metabotropic glutamate 5 receptor is necessary for extinction of cocaine-associated cues.
Topics: Animals; Benzamides; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Male; Pyrazoles; Pyridines; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Thiazoles | 2016 |
Haloperidol (but not ziprasidone) withdrawal potentiates sensitization to the hyperlocomotor effect of cocaine in mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Haloperidol; Humans; Male; Mice; Motor Activity; Piperazines; Schizophrenia; Substance Withdrawal Syndrome; Thiazoles | 2008 |
Administration of ziprasidone for 10 days increases cocaine toxicity in mice.
Topics: Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Synergism; Longevity; Male; Mice; Mice, Inbred Strains; Piperazines; Seizures; Thiazoles; Time Factors; Withholding Treatment | 2008 |
Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking.
Topics: Animals; Catheterization; Cocaine; Cocaine-Related Disorders; Cues; Dietary Sucrose; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Microinjections; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Self Administration; Thiazoles | 2009 |
Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in the transition to dependence.
Topics: Amino Acids; Analysis of Variance; Animals; Behavior, Addictive; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Male; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Self Administration; Thiazoles | 2010 |
(-)-2-oxa-4-aminobicylco[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) and 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine (MTEP) similarly attenuate stress-induced reinstatement of cocaine seeking.
Topics: Amino Acids; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Stimulants; Cocaine-Related Disorders; Conditioning, Operant; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Piperidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stress, Psychological; Thiazoles | 2012 |
Role of mGluR5 neurotransmission in reinstated cocaine-seeking.
Topics: Analysis of Variance; Animals; Biotinylation; Blotting, Western; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Extinction, Psychological; Glycine; Homer Scaffolding Proteins; Male; Microinjections; Nucleus Accumbens; Phenylacetates; Protein Binding; Protein Transport; Pyridines; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recurrence; Self Administration; Synaptic Transmission; Thiazoles | 2013 |
Assessment of propofol, midazolam and ziprasidone, or the combinations for the prevention of acute cocaine toxicity in a mouse model.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Drug Therapy, Combination; GABA Modulators; Male; Mice; Midazolam; Piperazines; Propofol; Seizures; Serotonin Antagonists; Thiazoles | 2013 |
Effect of daily dosing duration of direct and indirect dopamine receptor agonists: cocaine cross-tolerance following chronic regimens.
Topics: Analysis of Variance; Animals; Area Under Curve; Autoreceptors; Benzothiazoles; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Piperazines; Pramipexole; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Thiazoles; Time Factors | 2002 |
Acute dystonic reaction with moderate-dose ziprasidone.
Topics: Acute Disease; Adult; Alcoholism; Antipsychotic Agents; Cocaine-Related Disorders; Dystonic Disorders; Female; Hallucinations; Humans; Piperazines; Risk Factors; Thiazoles; Tongue Diseases; Torticollis; Violence | 2004 |
Ziprasidone pretreatment attenuates the lethal effects of cocaine in a mouse model.
Topics: Acute Disease; Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Injections, Intraperitoneal; Mice; Piperazines; Premedication; Random Allocation; Seizures; Single-Blind Method; Survival Analysis; Thiazoles; Treatment Outcome | 2005 |
Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications.
Topics: Allosteric Site; Animals; Cell Line; Cocaine; Cocaine-Related Disorders; Cricetinae; Cricetulus; Humans; Ligands; Male; Narcotics; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Self Administration; Structure-Activity Relationship; Thiazoles | 2006 |
Effects of group I metabotropic glutamate receptor antagonists on the behavioral sensitization to motor effects of cocaine in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Motor Activity; Pyridines; Quinolines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles; Time Factors | 2006 |
RNA interference-mediated inhibition of brain-derived neurotrophic factor expression increases cocaine's cytotoxicity in cultured cells.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cell Death; Cell Line, Tumor; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Down-Regulation; Gene Expression Regulation; Humans; Neurons; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2007 |
Ziprasidone, diazepam, or the combination for prevention of cocaine toxicity in a mouse model.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Confidence Intervals; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Male; Mice; Mice, Inbred Strains; Piperazines; Random Allocation; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric; Survival Rate; Thiazoles | 2007 |
Use of antipsychotics to treat cocaine toxicity?
Topics: Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Diazepam; Disease Models, Animal; Mice; Piperazines; Thiazoles; Treatment Outcome | 2008 |
Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity.
Topics: Animals; Anticonvulsants; Brain; Cocaine; Cocaine-Related Disorders; In Vitro Techniques; Ligands; Mice; Oxazoles; Piperazines; Radioligand Assay; Rats; Receptors, sigma; Seizures; Sigma-1 Receptor; Structure-Activity Relationship; Thiazoles | 2008 |
Pramipexole treatment for cocaine cravings.
Topics: Adult; Antidepressive Agents; Behavior, Addictive; Benzothiazoles; Bipolar Disorder; Cocaine-Related Disorders; Comorbidity; Diagnosis, Dual (Psychiatry); Dopamine Agonists; Drug Therapy, Combination; Humans; Lamotrigine; Male; Pramipexole; Thiazoles; Treatment Outcome; Triazines | 1999 |