thiazoles has been researched along with Cirrhosis in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.17) | 18.2507 |
| 2000's | 19 (39.58) | 29.6817 |
| 2010's | 19 (39.58) | 24.3611 |
| 2020's | 8 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bang, ML; Frossard, N; Gassmann, M; Nemska, S; Tavakoli, R | 1 |
| Fang, L; Kawanishi, H; Murohara, T; Ogawa, H; Ohashi, K; Otaka, N; Ouchi, N; Ozaki, Y; Takahara, K; Takefuji, M; Takikawa, T; Tatsumi, M | 1 |
| Choi, IW; Heo, SY; Hwang, CW; Jeong, MS; Jung, MJ; Jung, WK; Kang, HW; Kim, SW; Ko, SC; Lee, HS; Lee, KD; Oak, C; Oh, J; Park, WS | 1 |
| Bao, Y; Guo, Z; He, H; Li, Y; Niu, T; Pang, Y; Song, D; Tang, S | 1 |
| Bai, Y; Chen, B; Guo, Y; Hong, W; Lu, H; Papa, APD; Sun, L; Wu, C; Xiao, Y; Zhang, G; Zheng, S; Zhu, H | 1 |
| Chen, B; Chen, J; Huang, M; Huang, S; Liu, Y; Sun, Y; Wang, B; Wang, C; Wang, X; Xiong, L; Zhao, N | 1 |
| Bachmann, P; Böhm, M; Custodis, F; Millenaar, D; Schirmer, SH | 1 |
| Chen, GZ; Fu, LL; Liang, G; Liu, Q; Lu, XY; Sun, CC; Zhang, XH; Zheng, XY | 1 |
| Lei, Q; Li, G; Li, H; Lv, Z; Wang, Y; Yan, Z; Yi, T | 1 |
| Beyhoff, N; Blumrich, A; Foryst-Ludwig, A; Goeritzer, M; Grune, J; Jaeger, C; Kasch, J; Kintscher, U; Klopfleisch, R; Luettges, K; Müller, OJ; Ritter, D; Smeir, E; Thiele, A | 1 |
| Bai, M; Huang, S; Jia, Z; Jiang, M; Lei, J; Wang, T; Xu, M; Xu, S; Zhang, A | 1 |
| Gan, X; Lu, L; Miao, N; Shen, Y; Wang, B; Xu, D; Xu, J; Xue, H; Yang, L; Zhang, W; Zhou, L | 1 |
| Batteux, F; Carmona, F; Chapron, C; Chouzenoux, S; González-Foruria, I; Santulli, P | 1 |
| Ding, ZC; He, L; Liu, JH; Wang, H; Xie, L; Xing, S; Yi, CZ; Zhang, X; Zhou, P; Zou, ZM | 1 |
| Kataoka, N; Kinoshita, K; Kinugawa, K; Nakatani, Y; Nishida, K; Sakamoto, T; Tsujino, Y; Yamaguchi, Y | 1 |
| Al-aryahi, S; Cohen, N; Getachew, R; Guidone, D; Kamato, D; Little, PJ; Osman, N; Potocnik, SJ; Zheng, W | 1 |
| Abe, S; Hamano, S; Honma, S; Mitazaki, S; Nakamura, K; Shinohara, M; Takahashi, N; Yoshida, M | 1 |
| Chen, X; Dickhout, JG; Gao, B; Krepinsky, JC; Li, R; Lu, C; Mohammed-Ali, Z; Wang, TN; Yum, V | 1 |
| Candido, WM; Cannon, MV; de Boer, RA; Dokter, MM; Lindstedt, EL; Silljé, HH; van Gilst, WH; Yu, H | 1 |
| Ahn, JH; Hwang, JY; Hwang, SJ; Jeong, YH; Jung, MH; Kim, JH; Koh, JS; Kwak, CH; Lee, YS; Park, JR; Park, Y; Seo, HG | 1 |
| Chen, X; Gao, B; Krepinsky, JC; Mustafa, M; Wang, TN | 1 |
| Connelly, KA; Gilbert, RE; Kapus, A; Kepecs, D; Thai, K; Wu, X; Zhang, Y | 1 |
| Distler, JH; Distler, O | 1 |
| Akçören, Z; Büyükpamukcu, M; Demir, HA; Haliloglu, M; Varan, A | 1 |
| Beyer, C; Distler, JH; Distler, O | 1 |
| Inoue, K; Isaka, Y; Kaimori, J; Kawada, N; Matsui, I; Moriyama, T; Omori, H; Rakugi, H; Takabatake, Y; Ueda, Y; Yamamoto, R | 1 |
| Bierhaus, A; Cooper, ME; Gray, SP; Jandeleit-Dahm, KA; Jiaze, L; Pickering, R; Soro-Paavonen, A; Thomas, MC; Tikellis, C; Tsorotes, D; Watson, AM; Wong, B | 1 |
| Chae, MK; Jang, SY; Lee, EJ; Lee, SY; Yoon, JS | 1 |
| Garcia, JG; Gupta, MP; Kim, G; Moreno-Vinasco, L; Pillai, VB; Samant, S; Sundaresan, NR | 1 |
| Mizushige, K; Noma, T; Tsuji, T | 1 |
| Amiri, F; Diep, QN; Iglarz, M; Paradis, P; Schiffrin, EL; Touyz, RM; Viel, EC | 1 |
| Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC | 1 |
| Cooper, ME | 1 |
| Attia, E; Chen, J; El Chaar, M; Felsen, D; Hannafin, J; Poppas, DP | 1 |
| Braathen, LR; Córdoba, F; Kato, M; Nakashima, I; Vallan, C; von Felbert, V; Weis, J; Weissenberger, J | 1 |
| Aberra, M; Aten, J; Deira, G; Dragt, CA; Krediet, RT; van Westrhenen, R | 1 |
| Choi, SH; Hwang, SB | 1 |
| Chen, LH; Hsu, CY; Weng, CF | 1 |
| Matsumoto, H; Narahara, H; Nasu, K; Nishida, M; Yuge, A | 1 |
| De Windt, LJ; Smeets, PJ; Teunissen, BE; Van Bilsen, M; Van der Vusse, GJ; Willemsen, PH | 1 |
| Ansorge, S; Faust, J; Gollnick, HP; Lindenlaub, P; Neubert, K; Reinhold, D; Schultze, B; Simeoni, L; Thielitz, A; Vetter, RW; Wrenger, S | 1 |
| Abdalla, GK; Castro, EC; Faria, GE; Michelin, MA; Reis, MA; Silva, KT | 1 |
| Neaud, V; Rosenbaum, J | 1 |
| Inoue, Y; Kato, Y; Kawaguchi, M; Nakamura, S; Tamura, K; Tanigawa, K; Xu, G | 1 |
| Naukkarinen, A; Paljärvi, L; Repo, LP; Teräsvirta, ME | 1 |
| Johnson, JH; McCarthy, KJ; Routh, RE; Shaw, W; Walsh, K; Welbourne, TC | 1 |
| Akiyama, T; Fukumitsu, KI; Jia, DM; Otsuki, M; Tabaru, A | 1 |
| Cohen, EP; Fish, BL; Moulder, JE; Raife, TJ; Regner, KR | 1 |
3 review(s) available for thiazoles and Cirrhosis
| Article | Year |
|---|---|
Intracellular tyrosine kinases as novel targets for anti-fibrotic therapy in systemic sclerosis.
Topics: Animals; Benzamides; Clinical Trials as Topic; Dasatinib; Fibrosis; Humans; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Scleroderma, Systemic; Skin; Sulfonamides; Thiazoles | 2008 |
Pioglitazone: cardiovascular effects in prediabetic patients.
Topics: Animals; Aorta; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Fibrosis; Humans; Hypoglycemic Agents; Muscle, Smooth, Vascular; Myocardium; Pioglitazone; Prediabetic State; Thiazoles; Thiazolidinediones | 2002 |
Importance of advanced glycation end products in diabetes-associated cardiovascular and renal disease.
Topics: Animals; Atherosclerosis; Blood Glucose; Cardiomyopathies; Cardiovascular Agents; Diabetic Angiopathies; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Humans; Myocardium; Thiazoles | 2004 |
45 other study(ies) available for thiazoles and Cirrhosis
| Article | Year |
|---|---|
Antagonizing the CX3CR1 Receptor Markedly Reduces Development of Cardiac Hypertrophy After Transverse Aortic Constriction in Mice.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Chemokine CX3CL1; Collagen Type I, alpha 1 Chain; Constriction; CX3C Chemokine Receptor 1; Disease Models, Animal; Fibrosis; Hypertrophy, Left Ventricular; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Natriuretic Peptide, Brain; Pyrimidines; Signal Transduction; Thiazoles; Time Factors; Transforming Growth Factor beta1; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Factor Xa inhibitor, edoxaban ameliorates renal injury after subtotal nephrectomy by reducing epithelial-mesenchymal transition and inflammatory response.
Topics: Animals; Atrial Fibrillation; Disease Models, Animal; Epithelial-Mesenchymal Transition; Factor Xa Inhibitors; Fibrosis; Inflammation Mediators; Kidney; Mice; Nephrectomy; Pyridines; Renal Insufficiency, Chronic; Thiazoles | 2022 |
Fabrication and biological activity of polycaprolactone/phlorotannin endotracheal tube to prevent tracheal stenosis: An in vitro and in vivo study.
Topics: Animals; Biocompatible Materials; Cell Line; Fibrosis; Humans; In Vitro Techniques; Intubation, Intratracheal; Male; Materials Testing; Mucous Membrane; Polyesters; Rabbits; Tetrazolium Salts; Thiazoles; Trachea; Tracheal Stenosis; Transforming Growth Factor beta1 | 2020 |
12N-Substituted Matrinol Derivatives Inhibited the Expression of Fibrogenic Genes via Repressing Integrin/FAK/PI3K/Akt Pathway in Hepatic Stellate Cells.
Topics: Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Fibrosis; Focal Adhesion Kinase 1; Gene Expression Regulation; Hepatic Stellate Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Integrin alphaV; Models, Biological; Phosphatidylinositol 3-Kinase; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Thiazoles | 2019 |
Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis.
Topics: Animals; Cell Line; Diamines; Disease Models, Animal; Epithelial Cells; Fibrosis; Humans; Male; Myofibroblasts; Phenotype; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Signal Transduction; Thiazoles | 2019 |
Pharmacological Targeting of BET Bromodomains Inhibits Lens Fibrosis via Downregulation of MYC Expression.
Topics: Actins; Adult; Animals; Azepines; Blotting, Western; Cadherins; Cell Movement; Cell Proliferation; Down-Regulation; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibronectins; Fibrosis; Humans; Lens, Crystalline; Proteins; Proto-Oncogene Proteins c-myc; Rabbits; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Thiazoles; Transforming Growth Factor beta2; Triazoles | 2019 |
Effects of edoxaban and warfarin on vascular remodeling: Atherosclerotic plaque progression and collateral artery growth.
Topics: Animals; Anticoagulants; Atherosclerosis; Collateral Circulation; Disease Models, Animal; Factor Xa Inhibitors; Fibrosis; Hindlimb; Ischemia; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Skeletal; Neovascularization, Physiologic; Plaque, Atherosclerotic; Pyridines; Thiazoles; Vascular Remodeling; Warfarin | 2020 |
Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy.
Topics: Animals; Anti-Inflammatory Agents; Cardiomyopathies; Diet, High-Fat; Dose-Response Relationship, Drug; Fibrosis; HEK293 Cells; Humans; Inflammation; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Myocardium; NF-kappa B; Obesity; Piperazines; Rats; Signal Transduction; Thiazoles; Toll-Like Receptor 4 | 2020 |
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
Topics: Animals; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Fibrosis; Heat-Shock Proteins; Mice; Myocardial Infarction; Myofibroblasts; Signal Transduction; Sulfonamides; Thiazoles; Transforming Growth Factor beta1; Ubiquitin Thiolesterase; Up-Regulation | 2020 |
Liver X Receptor Agonist AZ876 Induces Beneficial Endogenous Cardiac Lipid Reprogramming and Protects Against Isoproterenol-Induced Cardiac Damage.
Topics: Aniline Compounds; Animals; Cellular Reprogramming; Disease Models, Animal; Fatty Acids; Fibrosis; Heart Diseases; Isoproterenol; Liver X Receptors; Male; Mice; Mice, 129 Strain; Myocardium; Thiazoles | 2021 |
Blocking AURKA with MK-5108 attenuates renal fibrosis in chronic kidney disease.
Topics: Animals; Aurora Kinase A; Biopsy; Cell Line; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Fibrosis; Humans; Infant; Kidney; Male; Mice; Rats; Renal Insufficiency, Chronic; Thiazoles | 2021 |
c-Myc promotes renal fibrosis by inducing integrin αv-mediated transforming growth factor-β signaling.
Topics: Angiotensin II; Animals; Extracellular Matrix; Fibroblasts; Fibrosis; Folic Acid; Integrin alphaV; Kidney; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-myc; Renal Insufficiency, Chronic; Signal Transduction; Thiazoles; Transforming Growth Factor beta; Up-Regulation; Ureteral Obstruction | 2017 |
Dysregulation of the ADAM17/Notch signalling pathways in endometriosis: from oxidative stress to fibrosis.
Topics: Actins; ADAM17 Protein; Adult; Advanced Oxidation Protein Products; Case-Control Studies; Collagen Type I; Diamines; Endometriosis; Endometrium; Female; Fibrosis; Gene Expression Regulation; Humans; Hydrogen Peroxide; Oxidative Stress; Primary Cell Culture; Prospective Studies; Quinolines; Receptors, Notch; Signal Transduction; Stromal Cells; Thiazoles | 2017 |
A Novel Inhibitor of Homodimerization Targeting MyD88 Ameliorates Renal Interstitial Fibrosis by Counteracting TGF-β1-Induced EMT in Vivo and in Vitro.
Topics: Actins; Animals; Cadherins; Cell Line; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Kidney; Mice; Myeloid Differentiation Factor 88; Piperazines; Protein Multimerization; Reperfusion Injury; Thiazoles; Transforming Growth Factor beta1 | 2018 |
Edoxaban suppresses the progression of atrial fibrosis and atrial fibrillation in a canine congestive heart failure model.
Topics: Animals; Atrial Fibrillation; Atrial Remodeling; Cardiac Pacing, Artificial; Dogs; Echocardiography; Electrophysiological Phenomena; Factor Xa Inhibitors; Fibrosis; Heart Atria; Heart Failure; Pyridines; Thiazoles | 2019 |
Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle.
Topics: Animals; Atherosclerosis; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Fibrosis; Glucokinase; Glucose; Insulin-Secreting Cells; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Thiazoles | 2014 |
Effect of cyclooxygenase (COX)-2 inhibition on mouse renal interstitial fibrosis.
Topics: Animals; Collagen; Cyclooxygenase 2 Inhibitors; Fibrosis; HSP47 Heat-Shock Proteins; Kidney; Kidney Diseases; Male; Meloxicam; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase Kinases; RNA, Messenger; Thiazines; Thiazoles | 2014 |
SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis.
Topics: Angiotensin II; Animals; Cells, Cultured; Endoplasmic Reticulum Stress; ErbB Receptors; Fibronectins; Fibrosis; Intracellular Signaling Peptides and Proteins; Kidney; Male; Membrane Proteins; Mesangial Cells; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency, Chronic; Serine Proteases; Sp1 Transcription Factor; Sterol Regulatory Element Binding Protein 1; Thiazoles; Transforming Growth Factor beta1; Up-Regulation | 2015 |
The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects.
Topics: Actins; Aniline Compounds; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Lipids; Lipogenesis; Liver X Receptors; Mice; Mice, Inbred C57BL; Organ Size; Orphan Nuclear Receptors; Reverse Transcriptase Polymerase Chain Reaction; Smad2 Protein; Smad3 Protein; Thiazoles; Transforming Growth Factor beta; Up-Regulation | 2015 |
Effects of Peroxisome Proliferator-Activated Receptor-δ Agonist on Cardiac Healing after Myocardial Infarction.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Movement; Chemokine CXCL12; Echocardiography; Fibrosis; Heart; Heart Ventricles; Infusions, Parenteral; Male; Matrix Metalloproteinase 9; Mesenchymal Stem Cells; Myocardial Infarction; Myocardium; Myofibroblasts; Platelet-Derived Growth Factor; PPAR delta; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiazoles; Transforming Growth Factor beta2; Ventricular Remodeling | 2016 |
SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction.
Topics: Animals; Apoptosis; Fibrosis; Kidney; Male; Mice; Pyridines; Signal Transduction; Sterol Regulatory Element Binding Proteins; Thiazoles; Transforming Growth Factor beta; Up-Regulation; Ureteral Obstruction | 2016 |
Sirtuin 1 Activation Reduces Transforming Growth Factor-β1-Induced Fibrogenesis and Affords Organ Protection in a Model of Progressive, Experimental Kidney and Associated Cardiac Disease.
Topics: Acetylation; Anilides; Animals; Biopsy; Blood Pressure; Collagen; Disease Models, Animal; Disease Progression; Feeding Behavior; Fibrosis; Gene Expression Regulation; Genes, Reporter; Glomerulosclerosis, Focal Segmental; Heart Diseases; Heart Function Tests; HEK293 Cells; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Proline; Rats, Inbred F344; Renal Insufficiency, Chronic; RNA, Messenger; Sirtuin 1; Smad3 Protein; Thiazoles; Transforming Growth Factor beta1 | 2017 |
Focal nodular hyperplasia of the liver and elevated alpha fetoprotein level in an infant with isolated hemihyperplasia.
Topics: alpha-Fetoproteins; Female; Fibrosis; Focal Nodular Hyperplasia; Hemorrhage; Humans; Hyperplasia; Hypertrophy; Infant; Magnetic Resonance Imaging; Thiazoles | 2008 |
Are tyrosine kinase inhibitors promising for the treatment of systemic sclerosis and other fibrotic diseases?
Topics: Animals; Benzamides; Clinical Trials as Topic; Dasatinib; Disease Models, Animal; Drugs, Investigational; ErbB Receptors; Fibrosis; Graft vs Host Disease; Humans; Imatinib Mesylate; Mixed Connective Tissue Disease; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Pulmonary Fibrosis; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Scleroderma, Systemic; Thiazoles | 2010 |
Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy.
Topics: Animals; Cell Movement; Cytokines; Disease Models, Animal; Febuxostat; Fibrosis; Kidney; Kidney Diseases; Macrophages; Male; Nephritis, Interstitial; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thiazoles; Transforming Growth Factor beta; Ureteral Obstruction; Xanthine Oxidase | 2012 |
Alagebrium reduces glomerular fibrogenesis and inflammation beyond preventing RAGE activation in diabetic apolipoprotein E knockout mice.
Topics: Albuminuria; Animals; Apolipoproteins E; Diabetes Mellitus, Experimental; Fibrosis; Glomerular Mesangium; Glomerulonephritis; Glycation End Products, Advanced; Male; Mice; Mice, Knockout; Nephritis; Oxidative Stress; Quinapril; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Tetrahydroisoquinolines; Thiazoles | 2012 |
Antifibrotic effects of quercetin in primary orbital fibroblasts and orbital fat tissue cultures of Graves' orbitopathy.
Topics: Actins; Adipose Tissue; Adult; Antioxidants; Biomarkers; Blotting, Western; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibronectins; Fibrosis; Graves Ophthalmopathy; Humans; L-Lactate Dehydrogenase; Male; Matrix Metalloproteinases; Middle Aged; Orbit; Orbital Diseases; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Wound Healing | 2012 |
Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling.
Topics: Animals; Animals, Newborn; Cardiomegaly; Coloring Agents; Echocardiography; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibrosis; Immunohistochemistry; Leucine; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NFATC Transcription Factors; Nicotinamide Phosphoribosyltransferase; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Ventricular Remodeling | 2013 |
Peroxisome proliferator-activated receptor-alpha and receptor-gamma activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Desoxycorticosterone; Endothelin-1; Endothelins; Fenofibrate; Fibrosis; Heart; Heart Ventricles; Hypertension; Myocardium; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Ventricular Remodeling | 2003 |
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine | 2003 |
Cyclooxygenase-2 inhibitor decreases extracellular matrix synthesis in stretched renal fibroblasts.
Topics: Animals; Cell Culture Techniques; Collagen; Cyclooxygenase Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Fibroblasts; Fibrosis; Kidney; Meloxicam; Pressure; Rats; Tensile Strength; Thiazines; Thiazoles; Transforming Growth Factor beta; Ureteral Obstruction | 2005 |
5-aminolaevulinic acid photodynamic therapy in a transgenic mouse model of skin melanoma.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Fibrosis; Flow Cytometry; Humans; Light; Melanoma; Melanoma, Experimental; Mice; Mice, Transgenic; Neoplasm Metastasis; Neoplasms, Experimental; NIH 3T3 Cells; Photochemotherapy; Photosensitizing Agents; Skin Neoplasms; Tetrazolium Salts; Thiazoles; Trypan Blue | 2005 |
Effects of inhibition of the polyol pathway during chronic peritoneal exposure to a dialysis solution.
Topics: Aldehyde Reductase; Animals; Benzothiazoles; Dialysis Solutions; Enzyme Inhibitors; Fibrosis; Glucose; Infusions, Parenteral; Lactic Acid; Male; Models, Animal; Neovascularization, Pathologic; Peritoneal Dialysis; Peritoneal Diseases; Peritoneum; Phthalazines; Polymers; Rats; Signal Transduction; Thiazoles | 2005 |
Modulation of the transforming growth factor-beta signal transduction pathway by hepatitis C virus nonstructural 5A protein.
Topics: Amino Acids; Animals; Blotting, Western; Cell Death; Cell Line; Cell Line, Tumor; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cytokines; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Fibrosis; Genes, Reporter; Glutathione Transferase; Humans; Immunoprecipitation; Liver; Luciferases; Microscopy, Confocal; Microscopy, Fluorescence; Phosphorylation; Plasmids; Protein Binding; Regeneration; Risk Factors; Signal Transduction; Smad3 Protein; Smad4 Protein; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transcriptional Activation; Transfection; Transforming Growth Factor beta; Viral Nonstructural Proteins | 2006 |
Involvement of P53 and Bax/Bad triggering apoptosis in thioacetamide-induced hepatic epithelial cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Cell Survival; Endothelial Cells; Fibrosis; Gene Expression Regulation; Genes, p53; Humans; Liver; Rats; Tetrazolium Salts; Thiazoles; Thioacetamide; Tumor Suppressor Protein p53 | 2006 |
Collagen gel contractility is enhanced in human endometriotic stromal cells: a possible mechanism underlying the pathogenesis of endometriosis-associated fibrosis.
Topics: Actins; Adult; Amides; Cell Differentiation; Collagen; Endometriosis; Endometrium; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibrosis; Gels; Humans; Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Stromal Cells; Tetrazolium Salts; Thiazoles | 2007 |
Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen; Fibroblasts; Fibrosis; Humans; Immunohistochemistry; Ligands; Myocytes, Cardiac; Peroxisome Proliferators; PPAR alpha; PPAR delta; PPAR gamma; Pyrimidines; Rats; Rats, Inbred Lew; Rosiglitazone; Thiazoles; Thiazolidinediones; Transduction, Genetic | 2007 |
Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts.
Topics: Actins; Animals; Collagen Type I; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Keloid; Lysine; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidines; Skin; Thiazoles; Transforming Growth Factor beta1 | 2008 |
Trypanosoma cruzi: the role of PGE2 in immune response during the acute phase of experimental infection.
Topics: Acute Disease; Animals; Cells, Cultured; Chagas Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Etoricoxib; Fibrosis; Male; Meloxicam; Mice; Mice, Inbred BALB C; Myocardium; Parasitemia; Prostaglandins; Pyridines; Spleen; Sulfones; Thiazines; Thiazoles; Trypanosoma cruzi | 2008 |
A red wine polyphenolic extract reduces the activation phenotype of cultured human liver myofibroblasts.
Topics: Actins; Cell Proliferation; Cell Survival; Cells, Cultured; DNA; Fibroblasts; Fibrosis; Flavonoids; Humans; Liver; Myofibrils; Phenols; Phenotype; Phosphorylation; Polyphenols; Tetrazolium Salts; Thiazoles; Wine | 2008 |
Lack of effect of CS-045, a new antidiabetic agent, on insulin secretion in the remnant pancreas after 90% pancreatectomy in rats.
Topics: Animals; Blood Glucose; Chromans; Fibrosis; Glucose Tolerance Test; Hypoglycemic Agents; In Vitro Techniques; Infusions, Parenteral; Insulin; Insulin Infusion Systems; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Pancreatectomy; Perfusion; Rats; Rats, Wistar; Thiazoles; Thiazolidinediones; Troglitazone | 1995 |
Pseudoexfoliation syndrome with poorly dilating pupil: a light and electron microscopic study of the sphincter area.
Topics: Adult; Aged; Aged, 80 and over; Amyloid; Benzothiazoles; Cataract Extraction; Cytoskeletal Proteins; Exfoliation Syndrome; Female; Fibrosis; Fluorescent Dyes; Humans; Immunoenzyme Techniques; Iris; Male; Microscopy, Fluorescence; Middle Aged; Muscle, Smooth; Pupil Disorders; Thiazoles | 1996 |
Troglitazone halts diabetic glomerulosclerosis by blockade of mesangial expansion.
Topics: Animals; Basement Membrane; Body Weight; Chondroitin Sulfate Proteoglycans; Chromans; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Fibrosis; Glomerular Mesangium; Hyperglycemia; Hyperinsulinism; Hypertriglyceridemia; Hypoglycemic Agents; Islets of Langerhans; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Troglitazone stimulates pancreatic growth in congenitally CCK-A receptor-deficient OLETF rats.
Topics: Aging; Amylases; Animals; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Fibrosis; Homeostasis; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipase; Male; Pancreas; Rats; Rats, Inbred OLETF; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Reference Values; Thiazoles; Thiazolidinediones; Troglitazone; Trypsin | 2001 |
Retinoic acid exacerbates experimental radiation nephropathy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Extracellular Matrix; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Kidney Failure, Chronic; Proteinuria; Pyridones; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Tretinoin; Uremia; Whole-Body Irradiation | 2002 |