Page last updated: 2024-08-21

thiazoles and Chronic Hepatitis C

thiazoles has been researched along with Chronic Hepatitis C in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (24.59)29.6817
2010's46 (75.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Almasio, PL; Barr, E; Bruno, S; Buti, M; Butterton, JR; Dutko, FJ; Fernsler, D; Gao, W; Grandhi, A; Hassanein, TI; Huang, HC; Jancoriene, L; Lawitz, E; Li, JJ; Liu, H; Muellhaupt, B; Nguyen, BT; Pearlman, B; Plank, RM; Robertson, MN; Ruane, PJ; Shepherd, A; Su, FH; Tannenbaum, B; Vierling, JM; Wahl, J; Wan, S; Yeh, WW; Yoshida, EM1
Agarwal, K; Barr, E; Ben-Ari, Z; Butterton, JR; Chen, HL; Dutko, FJ; Esteban, R; Fernsler, D; Fitzgerald, B; Foster, GR; Gane, EJ; Gao, W; Gerstoft, J; Grandhi, A; Huang, HC; Laursen, AL; Li, JJ; Liu, H; Nguyen, BT; Pianko, S; Plank, RM; Roberts, SK; Robertson, MN; Su, FH; Thompson, AJ; Wahl, J; Wan, S; Yeh, WW; Zeng, Z; Zeuzem, S; Zuckerman, E1
Agrawal, S; Asante-Appiah, E; Black, S; Bystol, K; Carr, D; Chase, R; Curry, S; Ferrari, E; Ingravallo, P; Kozlowski, J; Lahser, F; Liu, R; McMonagle, P; Rokosz, L; Tong, L; Yu, W1
Anderson, LJ; Asante-Appiah, E; Barr, E; Butterton, J; Fernsler, D; Gao, W; Gordon, SC; Hanna, GJ; Hassanein, T; Kelly, MM; Kowdley, KV; Lawitz, E; Liu, H; Poordad, F; Robertson, MN; Sahota, A; Vesay, M; Yeh, WW1
Barr, E; Burnevich, E; Buti, M; Feld, JJ; Foster, GR; Gane, E; Hanna, GJ; Jackson, B; Katchman, H; Klopfer, S; Lahser, F; Lawitz, E; Platt, HL; Rabinovitz, M; Robertson, MN; Shaughnessy, M; Tomasiewicz, K; Yeh, WW1
Cahn, P; Gun, A; Laufer, N; Ojeda, D; Quarleri, J; Sede, M1
Angus, P; Arasteh, K; Asselah, T; Böcher, WO; Bronowicki, JP; Gane, E; Heim, M; Kukolj, G; Larrey, D; Lohse, AW; Mensa, FJ; Müllhaupt, B; Nehmiz, G; Pol, S; Roberts, S; Schuchmann, M; Stern, JO; Zarski, JP; Zeuzem, S; Zoulim, F1
Deraz, DM; Elbaz, TM; Shehab, HM1
Asselah, T; Böcher, WO; Bourlière, M; Bronowicki, JP; Buti, M; Gallivan, JP; Gane, EJ; Kukolj, G; Lohse, AW; Mensa, FJ; Müllhaupt, B; Roberts, SK; Schuchmann, M; Soriano, V; Stern, JO; Vinisko, R; Zeuzem, S1
Kuboki, M; Nishiguchi, S; Omata, M; Sakai, Y; Sakamoto, W; Steinmann, G; Tsuda, Y; Tsunematsu, S; Urano, Y1
Berger, KL; Böcher, WO; Cartier, M; Datsenko, Y; Kukolj, G; Marquis, M; Massariol, MJ; Scherer, J; Steinmann, G; Stern, JO; Triki, I1
Tai, AW1
Laufer, NL; Rockstroh, JK1
Benhamou, Y; Shiffman, ML1
Shiffman, ML1
Gluud, C; Grevstad, B; Jakobsen, JC; Nikolova, K1
Agarwal, K; Austin, A; Barclay, ST; Brown, A; Dillon, JF; Dundas, P; Dusheiko, GM; Foster, GR; Fox, R; Hayes, PC; Leen, C; Miller, MH; Millson, C; Ryder, SD; Tait, J; Ustianowski, A1
Böcher, WO; Hennecke, N; Kayser, A; Kukolj, G; Lohmann, V; Martin, B; Neumann-Haefelin, C; Thimme, R1
Böcher, W; Buti, M; Buynak, RJ; Dufour, JF; Gallivan, JP; Mantry, P; Mensa, FJ; Soriano, V; Stern, JO; Taunk, J; Vinisko, R; Zeuzem, S1
Hodges, MR; Ottosen, S; Parsley, TB; Patick, AK; Raney, AK; van der Veer, E; van Doorn, LJ; Yang, L; Zeh, K1
Angus, P; Asselah, T; Böcher, W; Bourlière, M; Bronowicki, JP; Buti, M; Gallivan, JP; Gane, EJ; Lohse, AW; Manns, M; Mensa, FJ; Müllhaupt, B; Roberts, S; Sabo, JP; Schuchmann, M; Soriano, V; Stern, JO; Stickel, F; Voss, F; Zeuzem, S1
Agarwal, K; Asselah, T; Bourlière, M; Calinas, F; Crespo, J; Datsenko, Y; Dufour, JF; Ferenci, P; Forton, D; Foster, GR; Garcia, M; Kukolj, G; Maevskaya, M; Morano, LE; Moreno, C; Nishiguchi, S; Omata, M; Ouzan, D; Quinson, AM; Sarrazin, C; Scherer, J; Schuchmann, M; Stern, JO; Zehnter, E; Zeuzem, S1
Arastéh, K; Bhagani, S; Dieterich, D; Guardiola, JM; Ingiliz, P; Jain, MK; Kort, J; Laguno, M; Manero, M; Nelson, M; Rockstroh, JK; Soriano, V; Stern, JO; Tural, C; Vinisko, R1
Ambrosioni, J; Aouri, M; Böni, J; Cavassini, M; Decosterd, L; Fehr, J; Furrer, H; Günthard, HF; Haubitz, S; Kovari, H; Ledergerber, B; Metzner, KJ; Rauch, A; Schaerer, V; Schmid, P; Stoeckle, M1
Berger, KL; Kukolj, G; Quinson, AM; Ranga, M; Scherer, J; Sha, N; Stern, JO1
Ehsan, N; El-Fert, A; El-Said, H; Ezzat, S; Kohla, MA; Taha, H1
de Knegt, RJ; Maan, R; Veldt, BJ1
Asselah, T; Bourlière, M; Dufour, JF; Ferenci, P; Forton, D; Foster, GR; García-Samaniego, J; Maevskaya, M; Mantry, P; Oliveira, C; Quinson, AM; Sha, N; Stern, JO; Warner, N; Wright, D; Wright, M; Yoshida, EM1
Delgado, M; López-Cortés, LF; Macías, J; Ojeda-Burgos, G; Pineda, JA; Recio, E; Ríos, MJ; Rivero-Juárez, A; Téllez, F1
Amorosa, VK; Dou, D; Kang, M; Kottilil, S; Lee, YJ; Matining, R; Osinusi, A; Peters, MG; Petersen, T; Umbleja, T; Wang, C; Zhang, X1
Angus, P; Böcher, W; Buti, M; Buynak, RJ; Dufour, JF; Kadus, W; Mantry, P; Mensa, FJ; Pockros, PJ; Soriano, V; Stern, JO; Vinisko, R; Wright, D; Zeuzem, S1
Berger, KL; Côté-Martin, A; Kukolj, G; Marquis, M; Mensa, FJ; Nelson, DR; Sarrazin, C; Scherer, J; Sha, N; Stern, JO; Vinisko, R1
Bai, X; Calleja, JL; Forns, X; Garcia-Samaniego, J; Kaste, R; Manns, M; Sarrazin, C; Stern, JO; Wu, J1
El-Gohary, Y; Elfert, A; Kabil, SM; Keeffe, EB; Rossignol, JF1
Elazar, M; Glenn, JS; Korba, BE; Lui, P; Rossignol, JF1
Keeffe, EB; Rossignol, JF2
El-Gohary, Y; Elfert, A; Keeffe, EB; Rossignol, JF1
Darling, JM; Fried, MW1
Rossignol, JF1
Forde, KA; Reddy, KR1
Khattab, MA1
Elfert, A; Keeffe, EB; Rossignol, JF1
Takehara, T1
Khungar, V; Poordad, F1
Angus, P; Arasteh, K; Asselah, T; Boecher, WO; Bronowicki, JP; Gane, E; Haefner, C; Heim, M; Kukolj, G; Larrey, D; Lohse, A; Müllhaupt, B; Nehmiz, G; Pol, S; Roberts, S; Schuchmann, M; Stern, JO; Zarski, JP; Zeuzem, S; Zoulim, F1
Kabil, SM; Mounier, BI; Soliman, MS; Youssef, SM1
Chao, YS; Chern, JH; Hsu, TA; Hu, HS; Jiaang, WT; Lin, HM; Pu, SY; Wang, JC; Wu, CP; Wu, PS; Yang, CC; Yeh, TK; Yueh, A1
Abusamra, L; Bolcic, F; Cahn, P; Gun, A; Krolewiecki, A; Laufer, N; Pérez, H; Quarleri, J; Rolón, MJ; Salomón, H1
Bousquet, C; Dansereau, N; Dô, F; Kukolj, G; Lagacé, L; Llinas-Brunet, M; Marquis, M; Massariol, MJ; Maurice, R; Spickler, C; Thibeault, D; Triki, I; White, PW; Zhao, S1
Lok, AS; Sharma, P1
Hokari, A1
El Kassas, M; El Raziky, M; Esmat, G; Gamil, ME; Hassany, M1
Chao, YS; Chern, JH; Hsu, TA; Hu, HS; Jiaang, WT; Lin, HM; Wang, JC; Wang, WH; Wu, PS; Wu, SY; Yang, CC; Yeh, TK; Yueh, A1
Asselah, T; Bessone, F; Böcher, WO; Datsenko, Y; Fainboim, H; Ferenci, P; Heo, J; Kukolj, G; Lalezari, J; Leggett, B; Mauss, S; Nehmiz, G; Scherer, J; Steinmann, GG; Stern, JO; Sulkowski, MS1
Benhamou, Y; Calleja, JL; Chaves, RL; Crönlein, J; Erhardt, A; Forns, X; Hinrichsen, H; Nehmiz, G; Reiser, M; Sentjens, RE; Steinmann, GG; Wedemeyer, H; Yong, CL1
Lemon, SM; Li, K; Yi, M1
Avendano, C; Benhamou, Y; Hinrichsen, H; Nehmiz, G; Reesink, HW; Reiser, M; Riba, N; Steinmann, GG; Wedemeyer, H; Yong, CL1
Girish, C1
Benhamou, Y; Calleja, JL; Forns, X; Herrmann, E; Hinrichsen, H; Manns, MP; Nehmiz, G; Reesink, H; Reiser, M; Sarrazin, C; Steinmann, GG; Zeuzem, S1
Bes, M; Cubero, M; Esteban, JI; Esteban, R; Guardia, J; Otero, T; Quer, J; Sauleda, S1

Reviews

13 review(s) available for thiazoles and Chronic Hepatitis C

ArticleYear
Faldaprevir (BI 201335) for the treatment of hepatitis C in patients co-infected with HIV.
    Expert review of anti-infective therapy, 2014, Volume: 12, Issue:2

    Topics: Aminoisobutyric Acids; Antiviral Agents; Biological Availability; Clinical Trials as Topic; Coinfection; Drug Administration Schedule; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Leucine; Oligopeptides; Proline; Protease Inhibitors; Quinolines; Thiazoles; Virus Replication

2014
HCV F1/F2 patients: treat now or continue to wait.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34 Suppl 1

    Topics: Aminoisobutyric Acids; Antiviral Agents; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 3-Ring; Humans; Leucine; Oligopeptides; Proline; Quinolines; Ribavirin; Simeprevir; Sofosbuvir; Sulfonamides; Thiazoles; Treatment Outcome; Uridine Monophosphate

2014
Hepatitis C virus therapy in the direct acting antiviral era.
    Current opinion in gastroenterology, 2014, Volume: 30, Issue:3

    Topics: Aminoisobutyric Acids; Antiviral Agents; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Interferon-alpha; Leucine; Oligopeptides; Proline; Quinolines; Ribavirin; Sofosbuvir; Thiazoles; Uridine Monophosphate

2014
Nitazoxanide for chronic hepatitis C.
    The Cochrane database of systematic reviews, 2014, Apr-06, Issue:4

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Cause of Death; Hepatitis C, Chronic; Humans; Nitro Compounds; Randomized Controlled Trials as Topic; Thiazoles

2014
Management of Thrombocytopenia in Chronic Liver Disease: Focus on Pharmacotherapeutic Strategies.
    Drugs, 2015, Volume: 75, Issue:17

    Topics: Benzoates; Chronic Disease; Disease Management; Hepatitis C, Chronic; Humans; Hydrazines; Liver Diseases; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin

2015
Thiazolides: a new class of drugs for the treatment of chronic hepatitis B and C.
    Future microbiology, 2008, Volume: 3, Issue:5

    Topics: Antiviral Agents; Clinical Trials as Topic; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Nitro Compounds; Thiazoles

2008
Thiazolides: a new class of antiviral drugs.
    Expert opinion on drug metabolism & toxicology, 2009, Volume: 5, Issue:6

    Topics: Antiviral Agents; Clinical Trials as Topic; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Nitro Compounds; Thiazoles

2009
Hepatitis C virus infection and immunomodulatory therapies.
    Clinics in liver disease, 2009, Volume: 13, Issue:3

    Topics: Antibodies, Monoclonal; Antiviral Agents; Hepacivirus; Hepatitis C, Chronic; Humans; Immunoglobulins; Immunologic Factors; Immunotherapy; Interferons; Nitro Compounds; Ribavirin; Thiazoles; Toll-Like Receptors; Viral Hepatitis Vaccines

2009
Targeting host factors: a novel rationale for the management of hepatitis C virus.
    World journal of gastroenterology, 2009, Jul-28, Volume: 15, Issue:28

    Topics: Antibodies; Antiviral Agents; Cyclophilins; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Nitro Compounds; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, Virus; Thiazoles; Virus Internalization

2009
[Antiviral therapy for chronic hepatitis C: current status and perspectives].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2010, Volume: 130, Issue:2

    Topics: Antiviral Agents; DNA-Directed RNA Polymerases; Drug Administration Schedule; Drug Discovery; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Nitro Compounds; Oligopeptides; Polyethylene Glycols; Protease Inhibitors; Pyrimidine Nucleosides; Recombinant Proteins; Ribavirin; Thiazoles

2010
Emerging therapeutic options in hepatitis C virus infection.
    The American journal of managed care, 2011, Volume: 17 Suppl 4

    Topics: Aminoisobutyric Acids; Cyclopropanes; Drug Resistance, Viral; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 3-Ring; Humans; Indoles; Isoindoles; Lactams; Lactams, Macrocyclic; Leucine; Oligopeptides; Proline; Quinolines; Simeprevir; Sulfonamides; Thiazoles; Treatment Outcome; Viral Load; Virus Replication

2011
[Improved virologic response in chronic hepatitis C treated with peginterferon, ribavirin and add-on drug].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 4

    Topics: Antiviral Agents; Cyclosporine; Diterpenes; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fatty Alcohols; Female; Fluvastatin; Hepatitis C, Chronic; Humans; Indoles; Interferon-alpha; Male; Metformin; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Silybin; Silymarin; Thiazoles

2011
The future for the treatment of genotype 4 chronic hepatitis C.
    Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32 Suppl 1

    Topics: Albumins; Antiviral Agents; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Nitro Compounds; Oligopeptides; Polyethylene Glycols; Proline; Recombinant Proteins; Ribavirin; Serine Proteinase Inhibitors; Thiazoles; Time Factors; Viral Load; Vitamin D

2012

Trials

30 trial(s) available for thiazoles and Chronic Hepatitis C

ArticleYear
Safety and efficacy of a fixed-dose combination regimen of grazoprevir, ruzasvir, and uprifosbuvir with or without ribavirin in participants with and without cirrhosis with chronic hepatitis C virus genotype 1, 2, or 3 infection (C-CREST-1 and C-CREST-2,
    The lancet. Gastroenterology & hepatology, 2017, Volume: 2, Issue:11

    Topics: Adult; Amides; Antiviral Agents; Carbamates; Cyclopropanes; Drug Administration Schedule; Female; Genotype; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Liver Cirrhosis; Male; Middle Aged; Pyrrolidines; Quinoxalines; Ribavirin; Sulfonamides; Sustained Virologic Response; Thiazoles; Uridine

2017
Safety and efficacy of an 8-week regimen of grazoprevir plus ruzasvir plus uprifosbuvir compared with grazoprevir plus elbasvir plus uprifosbuvir in participants without cirrhosis infected with hepatitis C virus genotypes 1, 2, or 3 (C-CREST-1 and C-CREST
    The lancet. Gastroenterology & hepatology, 2017, Volume: 2, Issue:11

    Topics: Adult; Aged; Amides; Antiviral Agents; Benzofurans; Carbamates; Cyclopropanes; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Male; Middle Aged; Pyrrolidines; Quinoxalines; Sulfonamides; Sustained Virologic Response; Thiazoles; Uridine; Young Adult

2017
Efficacy and safety of ruzasvir 60 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4 or 6 infection.
    Journal of viral hepatitis, 2019, Volume: 26, Issue:6

    Topics: Adult; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Middle Aged; Pyrrolidines; Sustained Virologic Response; Thiazoles; Uridine

2019
Efficacy and safety of a two-drug direct-acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6.
    Journal of viral hepatitis, 2019, Volume: 26, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Interferons; Male; Middle Aged; Pyrrolidines; Ribavirin; RNA, Viral; Sustained Virologic Response; Thiazoles; Uridine; Young Adult

2019
Faldaprevir (BI 201335), deleobuvir (BI 207127) and ribavirin oral therapy for treatment-naive HCV genotype 1: SOUND-C1 final results.
    Antiviral therapy, 2013, Volume: 18, Issue:8

    Topics: Acrylates; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Drug Administration Schedule; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Interferon-alpha; Leucine; Oligopeptides; Polyethylene Glycols; Proline; Quinolines; Recombinant Proteins; Ribavirin; Thiazoles; Treatment Outcome; Viral Load

2013
Nitazoxanide plus pegylated interferon and ribavirin in the treatment of genotype 4 chronic hepatitis C, a randomized controlled trial.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:2

    Topics: Drug Therapy, Combination; Egypt; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Logistic Models; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Statistics, Nonparametric; Thiazoles

2014
Faldaprevir and deleobuvir for HCV genotype 1 infection.
    The New England journal of medicine, 2013, Aug-15, Volume: 369, Issue:7

    Topics: Adult; Aminoisobutyric Acids; Antiviral Agents; DNA-Directed RNA Polymerases; Enzyme Inhibitors; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Leucine; Male; Middle Aged; Oligopeptides; Proline; Protease Inhibitors; Quinolines; Thiazoles; Viral Load

2013
Safety and efficacy of faldaprevir with pegylated interferon alfa-2a and ribavirin in Japanese patients with chronic genotype-1 hepatitis C infection.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:1

    Topics: Adult; Aminoisobutyric Acids; Antiviral Agents; Asian People; Double-Blind Method; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Japan; Leucine; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Proline; Quinolines; Recombinant Proteins; Ribavirin; Thiazoles; Time Factors; Treatment Outcome

2014
Restoration of HCV-specific CD8+ T cell function by interferon-free therapy.
    Journal of hepatology, 2014, Volume: 61, Issue:3

    Topics: Acrylates; Adult; Aged; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Contraindications; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; In Vitro Techniques; Interferon alpha-2; Interferon-alpha; Leucine; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Proline; Quinolines; Recombinant Proteins; Ribavirin; Thiazoles; Treatment Outcome; Virus Replication

2014
Interferon-free treatment of chronic hepatitis C with faldaprevir, deleobuvir and ribavirin: SOUND-C3, a Phase 2b study.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:2

    Topics: Acrylates; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Leucine; Oligopeptides; Proline; Quinolines; Ribavirin; RNA, Viral; Thiazoles; Treatment Outcome

2015
In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1

    Topics: 5' Untranslated Regions; Antiviral Agents; Carbamates; Cyclohexanols; Drug Resistance, Viral; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Macrocyclic Compounds; MicroRNAs; Molecular Targeted Therapy; Mutation; Oligonucleotides; Oligopeptides; Pyrrolidines; Quinolines; Replicon; Thiazoles; Thiophenes; Valine

2015
Efficacy and safety of faldaprevir, deleobuvir, and ribavirin in treatment-naive patients with chronic hepatitis C virus infection and advanced liver fibrosis or cirrhosis.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:2

    Topics: Acrylates; Adult; Aged; Aged, 80 and over; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Female; Hepatitis C, Chronic; Humans; Leucine; Liver Cirrhosis; Male; Middle Aged; Oligopeptides; Proline; Quinolines; Ribavirin; Thiazoles; Young Adult

2015
STARTVerso1: A randomized trial of faldaprevir plus pegylated interferon/ribavirin for chronic HCV genotype-1 infection.
    Journal of hepatology, 2015, Volume: 62, Issue:6

    Topics: Adult; Aminoisobutyric Acids; Antiviral Agents; Double-Blind Method; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Leucine; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Proline; Quinolines; Recombinant Proteins; Ribavirin; RNA, Viral; Thiazoles

2015
Faldaprevir and pegylated interferon α-2a/ribavirin in individuals co-infected with hepatitis C virus genotype-1 and HIV.
    AIDS (London, England), 2015, Mar-13, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Aminoisobutyric Acids; Anti-Retroviral Agents; Antiviral Agents; Drug Therapy, Combination; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Leucine; Middle Aged; Oligopeptides; Polyethylene Glycols; Proline; Quinolines; Recombinant Proteins; Ribavirin; Thiazoles; Treatment Outcome; Viral Load; Viremia; Young Adult

2015
Baseline Polymorphisms and Emergence of Drug Resistance in the NS3/4A Protease of Hepatitis C Virus Genotype 1 following Treatment with Faldaprevir and Pegylated Interferon Alpha 2a/Ribavirin in Phase 2 and Phase 3 Studies.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10

    Topics: Amino Acid Substitution; Aminoisobutyric Acids; Antiviral Agents; Carrier Proteins; Double-Blind Method; Drug Resistance, Viral; Gene Expression; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Intracellular Signaling Peptides and Proteins; Leucine; Mutation; Oligopeptides; Polyethylene Glycols; Polymorphism, Genetic; Proline; Quinolines; Recombinant Proteins; Ribavirin; Thiazoles; Treatment Outcome; Viral Nonstructural Proteins

2015
Impact of nitazoxanide on sustained virologic response in Egyptian patients with chronic hepatitis C genotype 4: a double-blind placebo-controlled trial.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:1

    Topics: Adult; Antiparasitic Agents; Antiviral Agents; Double-Blind Method; Drug Therapy, Combination; Egypt; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Thiazoles; Viral Load

2016
Open-label study of faldaprevir plus peginterferon and ribavirin in hepatitis C virus genotype 1-infected patients who failed placebo plus peginterferon and ribavirin.
    Journal of viral hepatitis, 2016, Volume: 23, Issue:3

    Topics: Adult; Aged; Aminoisobutyric Acids; Antiviral Agents; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Leucine; Male; Middle Aged; Oligopeptides; Placebos; Proline; Quinolines; Ribavirin; Salvage Therapy; Thiazoles; Treatment Outcome

2016
Low Efficacy of Pegylated Interferon plus Ribavirin plus Nitazoxanide for HCV Genotype 4 and HIV Coinfection.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Adult; Antiviral Agents; Coinfection; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Nitro Compounds; Pilot Projects; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Thiazoles; Treatment Outcome

2015
Interferon Stimulated Gene Expression in HIV/HCV Coinfected Patients Treated with Nitazoxanide/Peginterferon-Alfa-2a and Ribavirin.
    AIDS research and human retroviruses, 2016, Volume: 32, Issue:7

    Topics: Adult; Antiviral Agents; Coinfection; Female; Gene Expression Profiling; Hepatitis C, Chronic; HIV Infections; Humans; Immunologic Factors; Interferon-alpha; Interferons; Leukocytes, Mononuclear; Male; Middle Aged; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Thiazoles

2016
Short article: Faldaprevir, deleobuvir and ribavirin in IL28B non-CC patients with HCV genotype-1a infection included in the SOUND-C3 phase 2b study.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:8

    Topics: Acrylates; Adult; Aminoisobutyric Acids; Antiviral Agents; Australia; Benzimidazoles; Drug Administration Schedule; Drug Therapy, Combination; Europe; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Interleukins; Leucine; Male; Middle Aged; Oligopeptides; Phenotype; Proline; Protease Inhibitors; Quinolines; Ribavirin; RNA, Viral; Sustained Virologic Response; Thiazoles; Time Factors; Treatment Outcome; United States

2016
HCVerso3: An Open-Label, Phase IIb Study of Faldaprevir and Deleobuvir with Ribavirin in Hepatitis C Virus Genotype-1b-Infected Patients with Cirrhosis and Moderate Hepatic Impairment.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Acrylates; Adolescent; Adult; Aged; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Leucine; Liver Cirrhosis; Male; Middle Aged; Oligopeptides; Prognosis; Proline; Quinolines; Ribavirin; RNA, Viral; Thiazoles; Viral Load; Young Adult

2016
Clinical trial: randomized, double-blind, placebo-controlled study of nitazoxanide monotherapy for the treatment of patients with chronic hepatitis C genotype 4.
    Alimentary pharmacology & therapeutics, 2008, Sep-01, Volume: 28, Issue:5

    Topics: Adult; Aged; Antiviral Agents; Double-Blind Method; Egypt; Female; Genotype; Hepatitis C, Chronic; Humans; Male; Middle Aged; Nitro Compounds; Risk Factors; RNA, Viral; Tablets; Thiazoles; Treatment Outcome

2008
Improved virologic response in chronic hepatitis C genotype 4 treated with nitazoxanide, peginterferon, and ribavirin.
    Gastroenterology, 2009, Volume: 136, Issue:3

    Topics: Adult; Antiparasitic Agents; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Thiazoles; Treatment Outcome; Young Adult

2009
Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection.
    Gastroenterology, 2011, Volume: 141, Issue:6

    Topics: Acrylates; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Leucine; Male; Middle Aged; Oligopeptides; Proline; Protease Inhibitors; Quinolines; Ribavirin; RNA-Dependent RNA Polymerase; RNA, Viral; Thiazoles; Treatment Outcome; Viral Load; Viral Nonstructural Proteins

2011
A controlled study of nitazoxanide (NTZ) 3 years after treatment of hepatitis C genotype 4.
    Journal of the Egyptian Society of Parasitology, 2011, Volume: 41, Issue:2

    Topics: Adult; Aged; Antiviral Agents; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; Nitro Compounds; RNA, Viral; Thiazoles

2011
Faldaprevir combined with pegylated interferon alfa-2a and ribavirin in treatment-naïve patients with chronic genotype 1 HCV: SILEN-C1 trial.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:6

    Topics: Adult; Aminoisobutyric Acids; Antiviral Agents; Carrier Proteins; Double-Blind Method; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Intracellular Signaling Peptides and Proteins; Leucine; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Proline; Quinolines; Recombinant Proteins; Ribavirin; Thiazoles; Viral Nonstructural Proteins

2013
Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients.
    Gastroenterology, 2004, Volume: 127, Issue:5

    Topics: Antiviral Agents; Carbamates; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hepatitis C, Chronic; Humans; Macrocyclic Compounds; Male; Middle Aged; Protease Inhibitors; Quinolines; RNA, Viral; Serine Endopeptidases; Thiazoles; Viral Load

2004
"Strong reasons make strong actions"--The antiviral efficacy of NS3/4A protease inhibitors.
    Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:3

    Topics: Antiviral Agents; Carbamates; Double-Blind Method; Drug Resistance, Viral; Hepatitis C, Chronic; Humans; Macrocyclic Compounds; Quinolines; RNA, Viral; Serine Proteinase Inhibitors; Thiazoles; Viral Nonstructural Proteins

2005
Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C.
    Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:4

    Topics: Administration, Oral; Adult; Carbamates; Double-Blind Method; Drug Administration Schedule; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Kinetics; Macrocyclic Compounds; Male; Middle Aged; Pilot Projects; Prospective Studies; Quinolines; Serine Proteinase Inhibitors; Thiazoles; Viral Load; Viral Nonstructural Proteins

2005
Viral kinetics in patients with chronic hepatitis C treated with the serine protease inhibitor BILN 2061.
    Antiviral therapy, 2006, Volume: 11, Issue:3

    Topics: Adult; Antiviral Agents; Area Under Curve; Carbamates; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Kinetics; Macrocyclic Compounds; Male; Middle Aged; Models, Biological; Quinolines; RNA, Viral; Serine Proteinase Inhibitors; Thiazoles

2006

Other Studies

18 other study(ies) available for thiazoles and Chronic Hepatitis C

ArticleYear
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:11

    Topics: Amides; Antiviral Agents; Carbamates; Cell Line, Tumor; Cyclopropanes; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Protease Inhibitors; Pyrrolidines; Quinoxalines; Replicon; Sulfonamides; Thiazoles; Uridine; Viral Nonstructural Proteins

2018
Analysis of sequences of hepatitis C virus NS5A genotype 1 in HIV-coinfected patients with a null response to nitazoxanide or peg-interferon plus ribavirin.
    Archives of virology, 2013, Volume: 158, Issue:9

    Topics: Amino Acid Sequence; Antiviral Agents; Coinfection; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Interferons; Molecular Sequence Data; Nitro Compounds; Polyethylene Glycols; Ribavirin; Sequence Alignment; Sequence Analysis, DNA; Thiazoles; Treatment Failure; Viral Nonstructural Proteins

2013
Baseline hepatitis C virus (HCV) NS3 polymorphisms and their impact on treatment response in clinical studies of the HCV NS3 protease inhibitor faldaprevir.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2

    Topics: Amino Acid Substitution; Aminoisobutyric Acids; Antiviral Agents; Clinical Trials as Topic; Drug Monitoring; Drug Resistance, Viral; Gene Expression; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Leucine; Mutation; Oligopeptides; Polymorphism, Genetic; Proline; Protease Inhibitors; Quinolines; Thiazoles; Viral Nonstructural Proteins

2014
An interferon-free, all-oral regimen is effective in treatment of genotype 1 chronic HCV infection.
    Evidence-based medicine, 2014, Volume: 19, Issue:2

    Topics: Antiviral Agents; DNA-Directed RNA Polymerases; Enzyme Inhibitors; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Oligopeptides; Thiazoles

2014
Review article: 2014 UK consensus guidelines - hepatitis C management and direct-acting anti-viral therapy.
    Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:12

    Topics: Aminoisobutyric Acids; Antiviral Agents; Drug Therapy, Combination; Hepatitis C, Chronic; Heterocyclic Compounds, 3-Ring; Humans; Interferon-alpha; Interferons; Leucine; Oligopeptides; Proline; Quinolines; Ribavirin; Simeprevir; Sofosbuvir; Sulfonamides; Thiazoles; Uridine Monophosphate

2014
Protease inhibitors to treat hepatitis C in the Swiss HIV Cohort Study: high efficacy but low treatment uptake.
    HIV medicine, 2015, Volume: 16, Issue:10

    Topics: Adult; Aminoisobutyric Acids; Antiviral Agents; Cohort Studies; Female; Hepatitis C, Chronic; HIV Infections; Humans; Leucine; Male; Middle Aged; Oligopeptides; Patient Acceptance of Health Care; Proline; Prospective Studies; Protease Inhibitors; Quinolines; RNA, Viral; Switzerland; Thiazoles; Viral Load

2015
Resistance Analyses of HCV NS3/4A Protease and NS5B Polymerase from Clinical Studies of Deleobuvir and Faldaprevir.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Acrylates; Amino Acid Substitution; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Carrier Proteins; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Resistance, Viral; Hepacivirus; Hepatitis C, Chronic; Humans; Intracellular Signaling Peptides and Proteins; Leucine; Mutation; Oligopeptides; Polymorphism, Genetic; Proline; Protease Inhibitors; Quinolines; Thiazoles; Treatment Outcome; Viral Nonstructural Proteins

2016
Potential for hepatitis C virus resistance to nitazoxanide or tizoxanide.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Antiviral Agents; Cell Line; Cytidine; Drug Resistance, Viral; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Nitro Compounds; Recombinant Proteins; Replicon; Ribavirin; Thiazoles; Virus Replication

2008
Nitazoxanide: beyond parasites toward a novel agent for hepatitis C.
    Gastroenterology, 2009, Volume: 136, Issue:3

    Topics: Antiparasitic Agents; Antiviral Agents; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Nitro Compounds; Thiazoles

2009
Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides.
    World journal of gastroenterology, 2009, Apr-21, Volume: 15, Issue:15

    Topics: Antiparasitic Agents; Antiviral Agents; Clinical Trials as Topic; Double-Blind Method; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Nitro Compounds; Placebos; Thiazoles

2009
Treatment of chronic hepatitis C using a 4-week lead-in with nitazoxanide before peginterferon plus nitazoxanide.
    Journal of clinical gastroenterology, 2010, Volume: 44, Issue:7

    Topics: Adult; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Nitro Compounds; Pilot Projects; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Thiazoles; Time Factors; Treatment Outcome; Young Adult

2010
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Amino Acid Substitution; Animals; Antiviral Agents; Cell Line, Tumor; Cell Survival; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Genes, Reporter; Hepacivirus; Hepatitis C, Chronic; Hepatocytes; High-Throughput Screening Assays; Humans; Interferon-alpha; Male; Rats; Replicon; Thiazoles; Viral Nonstructural Proteins

2012
No reduction of HCV viral load in HIV patients co-infected with HCV genotype 1 during a 30 days course of nitazoxanide monotherapy.
    Antiviral research, 2011, Volume: 92, Issue:3

    Topics: Adult; Antiviral Agents; Coinfection; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Male; Middle Aged; Nitro Compounds; Pilot Projects; Thiazoles; Treatment Failure; Viral Load

2011
In vitro resistance profile of the hepatitis C virus NS3 protease inhibitor BI 201335.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Amino Acid Substitution; Aminoisobutyric Acids; Antiviral Agents; Crystallography, X-Ray; Drug Resistance, Viral; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Inhibitory Concentration 50; Interferon-alpha; Kinetics; Leucine; Mutagenesis, Site-Directed; Mutation Rate; Oligopeptides; Phenotype; Proline; Protease Inhibitors; Quinolines; Replicon; Thiazoles; Viral Nonstructural Proteins

2012
Interferon-free treatment regimens for hepatitis C: are we there yet?
    Gastroenterology, 2011, Volume: 141, Issue:6

    Topics: Aminoisobutyric Acids; Antiviral Agents; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Leucine; Male; Oligopeptides; Proline; Quinolines; Ribavirin; RNA-Dependent RNA Polymerase; Thiazoles

2011
Resistance studies of a dithiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Amino Acid Substitution; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Mutation; Protein Binding; Pyrrolidines; Replicon; RNA, Viral; Sequence Analysis, RNA; Thiazoles; Viral Nonstructural Proteins

2013
Use of placebo: is it a boon or bane?
    Gastroenterology, 2005, Volume: 128, Issue:3

    Topics: Antiviral Agents; Carbamates; Clinical Trials as Topic; Ethics, Clinical; Hepacivirus; Hepatitis C, Chronic; Humans; Macrocyclic Compounds; Placebos; Protease Inhibitors; Quinolines; Serine Endopeptidases; Thiazoles

2005
Naturally occurring NS3-protease-inhibitor resistant mutant A156T in the liver of an untreated chronic hepatitis C patient.
    Virology, 2008, Jan-20, Volume: 370, Issue:2

    Topics: Adult; Amino Acid Sequence; Base Sequence; Carbamates; DNA, Viral; Drug Resistance, Viral; Genes, Viral; Hepacivirus; Hepatitis C, Chronic; Humans; Liver; Macrocyclic Compounds; Male; Molecular Sequence Data; Oligopeptides; Point Mutation; Proline; Quinolines; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazoles; Viral Nonstructural Proteins

2008