thiazoles has been researched along with Cancer of Colon in 150 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (2.00) | 18.7374 |
| 1990's | 31 (20.67) | 18.2507 |
| 2000's | 69 (46.00) | 29.6817 |
| 2010's | 40 (26.67) | 24.3611 |
| 2020's | 7 (4.67) | 2.80 |
| Authors | Studies |
|---|---|
| Duarte, D; Vale, N | 1 |
| Bejarano, I; de la Cruz-Martínez, F; Espino, J; Fernández-Delgado, E; Franco, L; Galán, C; Luna-Giles, F; Viñuelas-Zahínos, E | 1 |
| Chen, F; Chen, Y; Ding, J; Gong, CJ; He, T; Li, J; Nan, FJ; Shen, QQ; Su, MB; Su, Y; Zhang, SW; Zhang, YM | 1 |
| Jimi, S; Kamei, T; Oohata, Y; Takahata, S; Tamura, T | 1 |
| Koch, PD; Kohler, RH; Pittet, MJ; Rodell, CB; Weissleder, R | 1 |
| Sun, X; Yang, K; Yu, J; Zhao, W; Zheng, J | 1 |
| Ikeya, T; Kohashi, R; Murahashi, K; Nagamori, M; Sawada, T; Shirotsuki, J | 1 |
| Abd El-Fadeal, NM; Alomar, SY; Aloyouni, SY; El-Dosoky, M; El-Mistekawy, A; Elbahaie, AM; Hashish, AA; K El-Kherbetawy, M; Mohammad, HMF; Morsy, KM; Nafie, MS; Zaitone, SA | 1 |
| Correia-Branco, A; Duarte, D; Martel, F; Patrício, B; Vale, N | 1 |
| Brokstad, KA; Cheng, PF; Hoffman, PS; Kalland, KH; Ke, X; Levesque, MP; Olsen, JR; Oyan, AM; Qu, Y; Yuan, X; Zhang, W | 1 |
| Dai, GH; Mao, H; Wang, ZK; Wu, LL; Yang, L; Zhang, PF; Zhou, YH | 1 |
| Abdallah, AEM; Ahmed, EA; Mohareb, RM | 1 |
| Cantu, EJ; Forester, SC; Grimes, KL; Kaur, B; McCarthy, JJ; Stuart, CM | 1 |
| Ahmad, M; Ali, M; Chen, ZS; Gupta, P; Karadkhelkar, N; Narayanan, S; Nazim, U | 1 |
| Hayashi, K; Shimanouchi, T; Tatsui, T; Umakoshi, H | 1 |
| Gupta, S; Huang, JS; Jayathilaka, LP; Lee, BS; Lee, J | 1 |
| Lekshmi, SU; Rajasekharan, KN; Santhoshkumar, TR; Sengupta, S; Thamkachy, R; Thomas, SA; Vasudevan, S | 1 |
| Han, X; Hu, MM; Lu, BN; Peng, JY; Qi, Y; Xu, LN; Xu, YW | 1 |
| Fang, X; Jiang, S; Li, E; Liu, Z; Ma, Z; Wang, Y; Xu, L; Zhang, J; Zhang, K; Zhao, Y | 1 |
| Cassimeris, L; Kumar, R; Louis, XL; Rajasekharan, KN; Sengupta, S; Sivakumar, KC; Sreedevi, KJ; Thamkachy, R; Thomas, NE; Thomas, SA | 1 |
| Jaggi, M; Joshi, V; Negi, LM; Ronodip, K; Talegaonkar, S | 1 |
| Doki, Y; Ezoe, S; Hata, T; Kudo, T; Matsumoto, K; Mizushima, T; Mori, M; Nishimura, J; Sakai, D; Satoh, T; Sueda, T; Takemasa, I; Uemura, M; Yamamoto, H | 1 |
| Engene, N; Luesch, H; Paul, VJ; Salvador-Reyes, LA | 1 |
| Enoki, T; Hamano, K; Hosoyama, T; Kugimiya, N; Li, TS; Nishimoto, A; Ueno, K | 1 |
| Chen, JH; Chou, FP; Chyau, CC; Hsuan, SW; Hung, HY | 1 |
| Al-Harbi, SA; Al-Saidi, HM; Bashandy, MS; Emara, AAA; Mousa, TAA | 1 |
| Chen, L; He, L; Liu, Y; Ma, L; Nie, C; Pu, Y; Shao, M; Wang, F; Wu, W; Wu, Y; Yang, Z; Yu, K | 1 |
| Han, MH; Jung, M; Lee, S; Min, D | 1 |
| Kumar, R; Rajasekharan, KN; Sengupta, S; Thamkachy, R | 1 |
| Choi, YH; Ko, SH; Lee, JM; Park, H; Park, JH | 1 |
| Brunner, T; Hemphill, A; Müller, J; Nachbur, U; Sidler, D; Wastling, J | 1 |
| An, MJ; Cheon, JH; Hong, SY; Kim, ES; Kim, SW; Kim, TI; Kim, WH; Lee, HK; Lee, KR | 1 |
| Adam, BL; Chen, Q; Liu, Z; Royal, C; Xia, Z; Zhang, L; Zhu, Z | 1 |
| Chen, JS; Li, HS; Liang, QM; Long, JW; Wang, S; Yang, J | 1 |
| Ballinger, MD; Flanagan, WM; Fucini, RV; Hogan, JN; Taverna, P; VanderPorten, EC | 1 |
| Abbruzzese, JL; Chandra, J; Dallas, NA; Ellis, LM; Gallick, GE; Johnson, M; Kim, MP; Kopetz, S; Lesslie, DP; Parikh, NU; Park, SI | 1 |
| Hada, T; Kumamoto-Yonezawa, Y; Matsui, Y; Mizushina, Y; Sasaki, R; Sugimura, K; Suzuki, Y; Uryu, K; Yoshida, H | 1 |
| Banerjee, S; Kanwar, SS; Majumdar, AP; Nautiyal, J; Patel, BB; Sarkar, FH; Yu, Y | 1 |
| Borden, E; Cao, M; Fan, K; Gerson, S; Kundu, S; Lindner, DJ; Liu, L; Tuthill, R; Yi, T | 1 |
| Byeon, S; Hong, J; Kwan, JC; Law, BK; Liu, Y; Luesch, H; Salvador, LA; Ying, Y | 1 |
| Say, YH; Yap, YH | 1 |
| Davis, N; Halagowder, D; Sadullah, SS; Sivasitambaram, ND; Srinivasan, G; Subhadara, LB; Subramaniya, BR | 1 |
| Bensdorf, K; Cai, X; Cao, P; Gust, R; Huang, W; Li, Z; Liu, W; Qi, F; Qian, H; Wellner, A; Zhang, H; Zhou, J | 1 |
| Allen, JE; Brown, JM; Daniel, CJ; Dicker, DT; Dolloff, NG; Dorsey, JF; El-Deiry, WS; Furth, EE; Hart, LS; Jee, DI; Klein, PS; Kuribayashi, K; Liu, JJ; Liu, YY; Mayes, PA; Sears, RC | 1 |
| Li, Y; Yan, H; Yang, ST; Yang, Y; Zhang, X | 1 |
| Akbarzadeh, T; Bu, Y; Fallah-Tafti, A; Foroumadi, A; Hangauer, DG; Parang, K; Shafiee, A; Shirazi, AN; Tiwari, R | 1 |
| Aubourg, A; Chaigne, B; de Muret, A; Jonville-Bera, AP; Lagier, L; Machet, L; Samimi, M | 1 |
| Cho, HG; Choi, HS; Kang, BS; Khanal, P; Makarieva, TN; Yun, HJ | 1 |
| Cabrera, BL; Carethers, JM; Iwaizumi, M; Tajima, A; Tseng-Rogenski, S | 1 |
| Dogan, AL; Esendagli, G; Gönül, N; Guc, D; Hasçiçek, C; Şengel-Türk, CT | 1 |
| Chen, CR; Ji, ZN; Wang, Y; Xia, YH; Yao, SY; Zhang, Q | 1 |
| Jaganathan, SK | 1 |
| Fedoročko, P; Jendželovský, R; Koval, J; Mikeš, J; Papčová, Z; Plšíková, J | 1 |
| Kaminishi, M; Kusada, O; Mochizuki, Y; Shimoyama, S | 1 |
| Dabrowska-Iwanicka, A; Giermasz, A; Golab, J; Grzela, T; Hoser, G; Jakóbisiak, M; Jalili, A; Makowski, M; Marczak, M; Olszewska, D | 1 |
| Chan, UP; Chen, GG; Ip, PC; Lau, WY; Lee, JF; Wang, SH | 1 |
| Bronson, RT; Drori, S; Edelmann, W; Eng, C; Girnun, GD; Gonzalez, FJ; Kucherlapati, R; Mueller, E; Nambiar, P; Rosenberg, DW; Sarraf, P; Smith, WM; Spiegelman, BM | 1 |
| Boland, CR; Chang, DK; Gasche, C; Goel, A; Ricciardiello, L | 1 |
| Fujisawa, N; Ishimine, S; Kadowaki, T; Kawamori, T; Matsuhashi, N; Nakagama, H; Nakajima, A; Ochiai, M; Osawa, E; Sekihara, H; Wada, K | 1 |
| Girnun, GD; Spiegelman, BM | 1 |
| Berry, JM; Bradshaw, TD; Burger, AM; Seaton, A; Stevens, MF; Wang, B; Wells, G; Westwell, AD | 1 |
| Burgermeister, E; Liscovitch, M; Tencer, L | 1 |
| Gaschott, T; Stein, J | 1 |
| Gunduz, M; Haisa, M; Kawashima, R; Kimura, M; Nagai, N; Naomoto, Y; Shirakawa, Y; Takaoka, M; Takeda, H; Tanaka, N; Uetsuka, H | 1 |
| Ehrenborg, E; Gustafsson, MC; Harris, AL; Jarvis, M; Knight, D; Marshall, BR; Palmer, CN; Stephen, RL; Tatoud, R; Wolf, CR | 1 |
| Chang, HJ; Hong, SH; Jeon, E; Park, JG; Shin, YK; Yoo, BC | 1 |
| Grant, M; Guo, JM; Guo, YB; Lai, YF; Liu, DH; Liu, Q; Xiao, BX; Zhang, S | 1 |
| Solov'ev, IE; Solov'eva, OA | 1 |
| Bradshaw, TD; Carmichael, J; Martin, SG; Mukherjee, A; Stevens, MF; Westwell, AD | 1 |
| Chen, SZ; Jiang, M; Zhen, YS | 1 |
| Aalbersberg, W; Ireland, CM; Richardson, AD | 1 |
| Bailey, K; Bradshaw, TD; Chew, EH; Cookson, J; Harris, E; Laughton, CA; Matthews, CS; Monks, A; Shah, M; Stevens, MF; Wells, G; Westwell, AD | 1 |
| Davis, JJ; Dong, F; Fang, B; Guo, W; Teraishi, F; Wu, S; Zhang, L | 1 |
| Calvo, F; Cvitkovic, E; Koeppel, F; Laar, ES; Larsen, AK; Lokiec, F; Poindessous, V; Raymond, E; Serova, M; Waters, SJ | 1 |
| Brüne, B; Loitsch, S; Stein, J; Ulrich, S; von Knethen, A; Wächtershäuser, A | 1 |
| Hardcastle, IR; Mirza, AR; Walton, MI; Wilson, SC; Workman, P | 1 |
| Davis, JJ; Dong, F; Fang, B; Guo, W; Sasaki, J; Teraishi, F; Wu, S; Zhang, L | 1 |
| Billin, AN; Gonzalez, FJ; Kennett, MJ; Marin, HE; Peraza, MA; Peters, JM; Ward, JM; Willson, TM | 1 |
| Cheng, J; Xu, H; Yang, W; Yin, H; Zhao, Y; Zhou, Y | 1 |
| Barak, Y; Cormier, RT; Matise, I; McAlpine, CA | 1 |
| Costa, FT; de Carvalho, DD; Duran, N; Haun, M | 1 |
| Huang, MH; Li, X; Ouyang, Q; Tang, CW; Wang, CH | 1 |
| Battisti, RF; Chan, KK; Cheng, H; Fang, L; Martin, EW; Reigan, P; Ross, D; Shen, J; Sun, D; Wang, PG; Xin, Y | 1 |
| Chang, HO; Chang, LS; Chou, SY; Hsu, SC; Lee, YJ; Wang, SS; Yin, WK | 1 |
| Ding, H; Ge, HM; Jiao, RH; Liu, JY; Tan, RX; Xu, C; Xu, S; Zhu, HL | 1 |
| Ashton, GH; Brunton, VG; Clark, EA; Evans, TR; Frame, MC; Lee, FY; Macpherson, IR; Sansom, OJ; Serrels, A | 1 |
| Chiu, P; Ho, WK; Ko, JK; Leung, WC | 1 |
| Cai, PC; Hu, LH; Huang, JS; Wang, L; Yang, JH; Zhang, DT; Zhang, S; Zheng, JF | 1 |
| Acuña-Castroviejo, D; Camacho, E; Escames, G; Espinosa, A; Gallo, MA; García-Navarro, A; González-Puga, C; López, A; López, LC; López-Cantarero, M | 1 |
| Cai, J; He, L; Li, X; Luo, HS; Rong, H | 1 |
| Kobayashi, M; Natsume, T; Watanabe, J | 1 |
| Billin, AN; Borland, MG; Gonzalez, FJ; Hollingshead, HE; Peters, JM; Willson, TM | 1 |
| Ho, D; Huang, H; Osawa, E; Pierstorff, E | 1 |
| Abt, T; Bouralexis, S; Ganslmayer, M; Glaser, KB; Hahn, EG; Herold, C; Neureiter, D; Ocker, M; Okamoto, K; Zopf, S | 1 |
| Cheng, F; Chiang, W; Kuo, YH; Lee, MY; Lin, HY | 1 |
| Arango, ME; Bender, S; Higgins, J; Huber, A; Jessen, B; Koudriakova, T; Lewis, C; Los, G; Lundgren, K; Nonomiya, J; O'Connor, P; Price, S; Skaptason, J; Troche, G; Yan, Z; Yang, M; Zhang, C | 1 |
| Alexander, P; Davies, DE; Lelieveld, P; McCall, CJ; Richter, A; Stevens, MF | 1 |
| Furukawa, T; Ishibiki, K; Kase, S; Kodaira, S; Kubota, T; Takahara, T; Takeuchi, T; Teramoto, T; Watanabe, M; Yamaguchi, H | 1 |
| Fujita, S; Furukawa, T; Kase, S; Kubota, T; Kuo, TH; Kurihara, N; Saikawa, Y; Tanino, H; Watanabe, M; Yamamoto, T | 1 |
| Bérubé, G; Ford, CH; Gallant, M; Lau, A | 1 |
| Tan, BK; Wong, KT | 1 |
| Cendan, JC; Copeland, EM; Lind, DS; Souba, WW | 1 |
| Basha, G; Penninckx, F; Yap, P | 1 |
| Copaceanu, ML; Cottin, E; Coucke, PA; Li, YX; Mirimanoff, RO; Ozsahin, M; Paschoud, N | 1 |
| Haisa, M; Hatano, H; Naomoto, Y; Oka, Y; Orita, K; Tanaka, N; Yasuoka, Y | 1 |
| Chen, LB; Ikegawa, A; Kawakami, M; Koya, K; Ogawa, K; Shishido, T; Tatsuta, N; Ukai, T | 1 |
| Bradshaw, TD; Paull, KD; Schultz, RJ; Shi, DF; Stevens, MF; Wrigley, S | 1 |
| Guo, YS; Houston, CW; Jin, GF; Thompson, JC; Townsend, CM | 1 |
| Bruyneel, E; Chastre, E; Gespach, C; Kotelevets, L; Mareel, M; Myssiakine, E; Noë, V | 1 |
| Chen, LB; DeAngelo, DJ; Fletcher, C; Holden, SA; Jones, D; King, FJ; Mueller, E; Partridge, JB; Sarraf, P; Singer, S; Spiegelman, BM | 1 |
| Chiba, Y; Kitajima, M; Koya, K; Kubota, T; Matsumoto, Y; Otani, Y; Teramoto, T; Watanabe, M | 1 |
| Fukutomi, Y; Kojima, S; Matsushima-Nishiwaki, R; Moriwaki, H; Muto, Y; Okuno, M; Onogi, N | 1 |
| Chen, LB; Kawakami, M; Koya, K; Kuroiwa, H; Mochizuki, T; Motoji, N; Shigematsu, A; Shishido, T; Suzuki, N; Tatsuta, N | 1 |
| Kanayama, S; Kitamura, S; Kondo, S; Matsuzawa, Y; Miyazaki, Y; Shinomura, Y | 1 |
| Auwerx, J; Fruchart, JC; Gelman, L | 1 |
| Hotta, T; Ishimoto, K; Iwahashi, M; Matsuda, K; Tanaka, H; Tani, M; Tanimura, H; Tsunoda, T; Yamaue, H | 1 |
| Yanase, T | 1 |
| Bates, S; Blagosklonny, MV; Fojo, T; Robey, R | 1 |
| Mito, K | 1 |
| Bradshaw, TD; Diana, P; Seaton, A; Shi, DF; Stevens, MF; Wells, G; Westwell, AD | 1 |
| Gruszka, A; Karasek, M; Kunert-Radek, J; Melen-Mucha, G; Pawlikowski, M; Winczyk, K | 1 |
| Hussey, HJ; Tisdale, MJ | 1 |
| Roberts-Thomson, SJ | 1 |
| Aikou, T; Akiyama, S; Furukawa, T; Ikeda, R; Kitazono, M; Nagayama, S; Okumura, H; Seto, K; Sumizawa, T | 1 |
| Hosokawa, M; Kohno, H; Murakami, A; Okumura, A; Takashima, S; Tanaka, T; Yoshitani, S | 1 |
| Hosokawa, M; Kohno, H; Okumura, A; Takashima, S; Tanaka, T; Yamaguchi, N; Yoshitani , S | 1 |
| Borzilleri, R; Fairchild, CR; Kim, SH; Kramer, RA; Lee, FY; Long, BH; Reventos-Suarez, C; Rose, WC; Vite, GD | 1 |
| Ford, CH; Mathew, A; Osborne, PA; Rego, BG | 1 |
| Ansari, S; Black, J; DiBaise, JK; Karolski, WJ; Ratashak, A; Roy, HK | 1 |
| Montaner, B; Pérez-Tomás, R | 1 |
| Mahyar-Roemer, M; Roemer, K | 1 |
| Asai, S; Hatanaka, H; Kijima, H; Kondo, T; Mine, T; Miwa, T; Miyachi, H; Nagata, J; Nakamura, M; Scanlon, KJ; Takagi, A; Ueyama, Y; Yamazaki, H | 1 |
| Karasek, M; Pawlikowski, M; Winczyk, K | 1 |
| Franco, M; Latrofa, A; Liso, G; Reho, A; Trapani, G | 1 |
| Bolos, CA; Kortsaris, AH; Kyriakidis, DA; Papazisis, KT; Voyatzi, S; Zambouli, D | 1 |
| Hiraishi, H; Kojima, K; Shimada, T; Terano, A; Yoshiura, K | 1 |
| Horgen, FD; Kazmierski, EB; Scheuer, PJ; Westenburg, HE; Yoshida, WY | 1 |
| Kitayama, J; Nagawa, H; Osada, T; Saito, S; Shibata, Y; Sunami, E; Tomozawa, S; Tsuno, NH; Tsuruo, T; Yamaguchi, H | 1 |
| Azzi, S; Guillemin, F; Lignon, D; Merlin, JL; Ramacci, C; Zeghari, N | 1 |
| Berger, MR; Galeano, A; Keppler, BK | 1 |
| Asanuma, F; Fujinaga, S; Kawamura, E; Kubota, T; Kurokawa, T; Lee, KE; Suzuki, T; Suzuki, Y; Yamada, T; Yamada, Y | 1 |
| Isobe, K; Nakashima, I; Satta, T; Takagi, H; Yamauchi, M | 1 |
| Furukawa, T; Ishibiki, K; Kase, S; Kitajima, M; Kodaira, S; Kubota, T; Kuo, TH; Nishibori, H; Saikawa, Y; Watanabe, M | 1 |
| Khoury, MD; Pereira, MA | 1 |
| Suto, A | 1 |
| Furukawa, T; Ishibiki, K; Kase, S; Kodaira, S; Kubota, T; Suto, A; Takahara, T; Takeuchi, T; Yamaguchi, H | 1 |
| Cory, JG; Fox, JG; Koneru, PB; Lien, EJ; Matsumoto, M; Wang, PH | 1 |
| Ford, CH; Richardson, VJ; Tsaltas, G | 1 |
| Lalezari, I; Schwartz, EL | 1 |
| Baguley, BC; Finlay, GJ; Wilson, WR | 1 |
4 review(s) available for thiazoles and Cancer of Colon
| Article | Year |
|---|---|
PPARgamma ligands: taking Ppart in chemoprevention.
Topics: Animals; Colonic Neoplasms; Humans; Ligands; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transcription Factors | 2003 |
An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer.
Topics: Adipocytes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Cycle; Cell Differentiation; Cell Transformation, Neoplastic; Colonic Neoplasms; Energy Metabolism; Fatty Acids; Gene Expression Regulation; Homeostasis; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Inflammation; Intestinal Mucosa; Lipid Metabolism; Macrophages; Neoplasms; Peroxisome Proliferators; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Thiazoles; Transcription Factors | 1999 |
[Physiological function of peroxisome proliferator-activated receptor].
Topics: Animals; Blood Cells; Cell Differentiation; Cell Division; Colonic Neoplasms; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Ligands; Lipoprotein Lipase; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic | 1999 |
Peroxisome proliferator-activated receptors in tumorigenesis: targets of tumour promotion and treatment.
Topics: Animals; Cell Cycle; Cell Differentiation; Colonic Neoplasms; Humans; Lipid Metabolism; Liver Neoplasms; Neoplasms; Nuclear Proteins; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2000 |
146 other study(ies) available for thiazoles and Cancer of Colon
| Article | Year |
|---|---|
Synergistic Interaction of CPP2 Coupled with Thiazole Derivates Combined with Clotrimazole and Antineoplastic Drugs in Prostate and Colon Cancer Cell Lines.
Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell-Penetrating Peptides; Clotrimazole; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; Male; Paclitaxel; Prostatic Neoplasms; Thiazoles | 2021 |
Pt(II) and Pd(II) complexes with a thiazoline derivative ligand: Synthesis, structural characterization, antiproliferative activity and evaluation of pro-apoptotic ability in tumor cell lines HT-29 and U-937.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cisplatin; Colonic Neoplasms; Coordination Complexes; Humans; Leukemia, Myeloid, Acute; Organometallic Compounds; Palladium; Thiazoles; Tumor Cells, Cultured | 2020 |
Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors.
Topics: Animals; Cell Line, Tumor; Colitis; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Humans; Mice; Molecular Docking Simulation; Structure-Activity Relationship; Thiazoles; Tissue Distribution; Xenograft Model Antitumor Assays | 2020 |
[Successful Management of Deep Vein Thromboembolism and Pulmonary Embolism by Edoxaban for Long-Term 5-FU-Based Chemotherapy for Colon Cancer-A Case Report].
Topics: Aged; Anticoagulants; Colonic Neoplasms; Fluorouracil; Humans; Pulmonary Embolism; Pyridines; Thiazoles; Thromboembolism; Venous Thromboembolism | 2019 |
Myeloid Cell-Targeted Nanocarriers Efficiently Inhibit Cellular Inhibitor of Apoptosis for Cancer Immunotherapy.
Topics: Alkynes; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Dendritic Cells; Drug Carriers; Drug Evaluation, Preclinical; Immunotherapy; Interleukin-12; Mice; Myeloid Cells; Nanoparticles; Oligopeptides; Small Molecule Libraries; Thiazoles | 2020 |
Synergistic tumor inhibition of colon cancer cells by nitazoxanide and obeticholic acid, a farnesoid X receptor ligand.
Topics: Animals; beta Catenin; Carcinogenesis; Cell Proliferation; Chenodeoxycholic Acid; Colonic Neoplasms; Drug Synergism; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heterografts; Humans; Ligands; Liver; Mice; Molecular Targeted Therapy; Nitro Compounds; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles | 2021 |
[A Case of Metastatic and Recurrent Colon Cancer Whose QOL Kept Longly by Multidisciplinary Treatment Including Six Times Surgical Operation].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Humans; Male; Neoplasm Recurrence, Local; Quality of Life; Thiazoles | 2021 |
Antitumor Activity of Nitazoxanide against Colon Cancers: Molecular Docking and Experimental Studies Based on Wnt/β-Catenin Signaling Inhibition.
Topics: Animals; Antiparasitic Agents; Apoptosis; beta Catenin; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; HCT116 Cells; Humans; Male; Mice; Molecular Docking Simulation; Nitro Compounds; Proliferating Cell Nuclear Antigen; Thiazoles; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2021 |
In vitro studies on the inhibition of colon cancer by amino acid derivatives of bromothiazole.
Topics: Amino Acids; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Proliferation; Colon; Colonic Neoplasms; Halogenation; Humans; Thiazoles | 2017 |
Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer.
Topics: Animals; Antineoplastic Agents; beta Catenin; Cell Line, Tumor; Citrullination; Colonic Neoplasms; Gene Knockout Techniques; Humans; Nitro Compounds; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Thiazoles; Wnt Signaling Pathway | 2018 |
Long non-coding RNA LINC00261 sensitizes human colon cancer cells to cisplatin therapy.
Topics: Analysis of Variance; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Blotting, Western; Cell Migration Assays; Cell Proliferation; Cisplatin; Colonic Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Long Noncoding; Signal Transduction; Tetrazolium Salts; Thiazoles | 2017 |
Synthesis and cytotoxicity evaluation of thiazole derivatives obtained from 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene- 3-carbonitrile.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytotoxins; Hep G2 Cells; Humans; Liver Neoplasms; Nasopharyngeal Neoplasms; Stomach Neoplasms; Thiazoles | 2017 |
Enhancing the Cancer Cell Growth Inhibitory Effects of Table Grape Anthocyanins.
Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caco-2 Cells; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Female; Fruit; Glucosides; HT29 Cells; Humans; Methylation; Nitriles; Oxidative Stress; Phytotherapy; Plant Extracts; Tetrazolium Salts; Thiazoles; Vitis | 2018 |
Anti-cancer effect of Indanone-based thiazolyl hydrazone derivative on colon cancer cell lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Glutathione; Humans; Hydrazones; Indans; M Phase Cell Cycle Checkpoints; Mice; Mitosis; Protein Multimerization; Protein Structure, Quaternary; Reactive Oxygen Species; Thiazoles; Tubulin | 2019 |
Enhanced cytotoxicity for colon 26 cells using doxorubicin-loaded sorbitan monooleate (Span 80) vesicles.
Topics: Animals; Cell Culture Techniques; Cell Line, Tumor; Colonic Neoplasms; Doxorubicin; Drug Delivery Systems; Female; Flow Cytometry; Hexoses; Liposomes; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Tetrazolium Salts; Thiazoles; Transport Vesicles | 2013 |
HPLC-MTT assay: anticancer activity of aqueous garlic extract is from allicin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colonic Neoplasms; Coloring Agents; Disulfides; Garlic; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Plant Extracts; Sulfinic Acids; Tetrazolium Salts; Thiazoles | 2013 |
Upregulation of DR5 receptor by the diaminothiazole DAT1 [4-amino-5-benzoyl-2-(4-methoxy phenyl amino) thiazole] triggers an independent extrinsic pathway of apoptosis in colon cancer cells with compromised pro and antiapoptotic proteins.
Topics: Apoptosis; bcl-Associated Death Protein; Caspase 8; Colonic Neoplasms; Down-Regulation; HCT116 Cells; Humans; Mitochondria; Receptors, TNF-Related Apoptosis-Inducing Ligand; Serpins; Thiazoles; Triazoles; Up-Regulation; Viral Proteins | 2013 |
Mechanisms involved in the cytotoxic effects of berberine on human colon cancer HCT-8 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Berberine; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Flow Cytometry; Humans; L-Lactate Dehydrogenase; Medicine, Chinese Traditional; Microscopy, Fluorescence; Prohibitins; Repressor Proteins; RNA, Messenger; S Phase; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53; Vimentin | 2012 |
Comprehensive analysis for histone acetylation of human colon cancer cells treated with a novel HDAC inhibitor.
Topics: Acetylation; Antineoplastic Agents; Colonic Neoplasms; Depsipeptides; Epigenesis, Genetic; HCT116 Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Isotope Labeling; Thiazoles | 2014 |
Reversible action of diaminothiazoles in cancer cells is implicated by the induction of a fast conformational change of tubulin and suppression of microtubule dynamics.
Topics: Cell Proliferation; Colchicine; Colonic Neoplasms; HCT116 Cells; Humans; Hydrogen Bonding; Microtubules; Mitosis; Molecular Dynamics Simulation; Protein Conformation; Thiazoles; Tubulin | 2014 |
Hyaluronic acid decorated lipid nanocarrier for MDR modulation and CD-44 targeting in colon adenocarcinoma.
Topics: Adenocarcinoma; Camptothecin; Colonic Neoplasms; Coumarins; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Irinotecan; Lipids; Nanoparticles; Thiazoles | 2015 |
Safety and pharmacokinetics of S-1 in a recurrent colon cancer patient with chronic myeloid leukemia treated with dasatinib: a case report.
Topics: Aged; Antimetabolites, Antineoplastic; Area Under Curve; Colonic Neoplasms; Dasatinib; Drug Combinations; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Neoplasm Metastasis; Neoplasm Recurrence, Local; Oxonic Acid; Protein Kinase Inhibitors; Pyrimidines; Tegafur; Thiazoles | 2014 |
Targeted natural products discovery from marine cyanobacteria using combined phylogenetic and mass spectrometric evaluation.
Topics: Biological Products; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyanobacteria; Cytotoxins; Depsipeptides; HCT116 Cells; Humans; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phylogeny; Thiazoles | 2015 |
The c-MYC-ABCB5 axis plays a pivotal role in 5-fluorouracil resistance in human colon cancer cells.
Topics: Aged; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinogenesis; Cell Line, Tumor; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-myc; Signal Transduction; Thiazoles | 2015 |
The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Autophagy; BH3 Interacting Domain Death Agonist Protein; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cytochromes c; Humans; Indoles; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Mitochondria; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Wasabia; Xenograft Model Antitumor Assays | 2016 |
Synthesis, spectroscopic properties, molecular docking, anti-colon cancer and anti-microbial studies of some novel metal complexes for 2-amino-4-phenylthiazole derivative.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Catalytic Domain; Cell Death; Chlorocebus aethiops; Colonic Neoplasms; Coordination Complexes; Electron Spin Resonance Spectroscopy; Electrons; Fungi; HCT116 Cells; Humans; Ligands; Mass Spectrometry; Metals; Methotrexate; Microbial Sensitivity Tests; Molecular Docking Simulation; Proton Magnetic Resonance Spectroscopy; Schiff Bases; Spectrophotometry, Infrared; Tetrahydrofolate Dehydrogenase; Thermogravimetry; Thiazoles; Vero Cells; Vibration | 2015 |
Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
Topics: Angiogenesis Inhibitors; Animals; Antimitotic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Line, Tumor; Cell Movement; Colchicine; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Protein Binding; Stilbenes; Structure-Activity Relationship; Thiazoles; Tubulin Modulators; Xenograft Model Antitumor Assays | 2015 |
First Synthesis of Novel Aminophenyl Pyridinium-5-(hydroxybenzoyl)-hydrazonomethyl-2-oxothiazol-3-ide Derivatives and Evaluation of Their Anticancer Activities.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Pyridinium Compounds; Structure-Activity Relationship; Thiazoles | 2015 |
ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells.
Topics: Animals; Antimitotic Agents; Apoptosis; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Inhibitory Concentration 50; Mice, Inbred NOD; Mice, SCID; Models, Biological; Mutation; Phosphorylation; Protein Transport; raf Kinases; ras Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Thiazoles; Toxicity Tests, Acute; Tumor Suppressor Protein p53; Up-Regulation | 2016 |
Troglitazone Enhances the Apoptotic Response of DLD-1 Colon Cancer Cells to Photodynamic Therapy.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromans; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Photochemotherapy; PPAR gamma; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Troglitazone | 2016 |
Thiazolides inhibit growth and induce glutathione-S-transferase Pi (GSTP1)-dependent cell death in human colon cancer cells.
Topics: Apoptosis; Benzamides; Caco-2 Cells; Cell Growth Processes; Colonic Neoplasms; Doxorubicin; Flow Cytometry; Glutathione S-Transferase pi; Humans; Phosphatidylserines; RNA, Small Interfering; Thiazoles | 2008 |
Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells.
Topics: Angiogenesis Inhibitors; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Endothelium, Vascular; Gene Expression Regulation, Neoplastic; Humans; Models, Biological; Neoplasm Metastasis; Neovascularization, Pathologic; Pregnenediones; Promoter Regions, Genetic; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2008 |
Specific reversal of MDR1/P-gp-dependent multidrug resistance by RNA interference in colon cancer cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Doxorubicin; Drug Resistance, Multiple; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors; Vincristine | 2008 |
Octreotide inhibits growth of colonic cancer SW480 cells by modulating the Wnt/P-catenin pathway.
Topics: Antineoplastic Agents, Hormonal; Apoptosis; beta Catenin; Blotting, Western; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Indicators and Reagents; Octreotide; Oligonucleotide Array Sequence Analysis; Signal Transduction; Tetrazolium Salts; Thiazoles; Wnt Proteins | 2009 |
The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with chemotherapeutics and synergy with microtubule-targeted agents in a colon carcinoma model.
Topics: Animals; Antineoplastic Agents; Aurora Kinases; Cell Proliferation; Cell Survival; Colonic Neoplasms; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Mice; Microtubules; Phenylurea Compounds; Protein Serine-Threonine Kinases; Spindle Apparatus; Thiazoles; Xenograft Model Antitumor Assays | 2009 |
Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Growth Processes; Colonic Neoplasms; Dasatinib; Down-Regulation; Drug Synergism; HCT116 Cells; HT29 Cells; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Organoplatinum Compounds; Oxaliplatin; Oxidative Stress; Protein Kinase Inhibitors; Pyrimidines; Random Allocation; Reactive Oxygen Species; src-Family Kinases; Thiazoles; Vascular Endothelial Growth Factor A | 2009 |
Enhancement of human cancer cell radiosensitivity by conjugated eicosapentaenoic acid - a mammalian DNA polymerase inhibitor.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Comet Assay; DNA Damage; DNA Repair; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Humans; Neoplasms; Nucleic Acid Synthesis Inhibitors; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2010 |
Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Antineoplastic Agents; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; Curcumin; Dasatinib; Drug Synergism; Electrophoretic Mobility Shift Assay; Endothelium, Vascular; ErbB Receptors; Female; Humans; Immunoenzyme Techniques; Intestinal Neoplasms; Mice; Mice, Knockout; Neoplasm Invasiveness; Neovascularization, Pathologic; NF-kappa B; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; src-Family Kinases; Thiazoles; Umbilical Veins | 2011 |
Tyrosine phosphatase inhibitor-3 sensitizes melanoma and colon cancer to biotherapeutics and chemotherapeutics.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Drug Synergism; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Melanoma; Mice; Recombinant Proteins; Substrate Specificity; Thiazoles; Xenograft Model Antitumor Assays | 2010 |
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Colonic Neoplasms; Depsipeptides; Down-Regulation; Drug Stability; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Immunohistochemistry; Mass Spectrometry; Mice; Mice, Nude; Molecular Structure; Oligonucleotide Array Sequence Analysis; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Xenograft Model Antitumor Assays | 2010 |
Resistance against apoptosis by the cellular prion protein is dependent on its glycosylation status in oral HSC-2 and colon LS 174T cancer cells.
Topics: Anti-Bacterial Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Endoplasmic Reticulum; Glycosylation; HeLa Cells; Humans; Mitochondria; Mouth Neoplasms; Oxidative Stress; Prions; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Tunicamycin | 2011 |
Apoptosis inducing effect of plumbagin on colonic cancer cells depends on expression of COX-2.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Comet Assay; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Naphthoquinones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2011 |
Synthesis and biological activities of 2-amino-thiazole-5-carboxylic acid phenylamide derivatives.
Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Combinatorial Chemistry Techniques; Dasatinib; Female; HT29 Cells; Humans; Inhibitory Concentration 50; Leukemia; Pyrimidines; Structure-Activity Relationship; Thiazoles | 2011 |
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Camptothecin; CDC2 Protein Kinase; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitor of Apoptosis Proteins; Irinotecan; Mice; Mice, Nude; Neoplasm Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-myb; Pyrimidines; Recombinant Proteins; RNA, Small Interfering; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2011 |
Isothiocyanates from Broccolini seeds induce apoptosis in human colon cancer cells: proteomic and bioinformatic analyses.
Topics: Amino Acid Sequence; Antineoplastic Agents, Phytogenic; Apoptosis; Brassica; Cell Line, Tumor; Colonic Neoplasms; Coloring Agents; Computational Biology; Electrophoresis, Gel, Two-Dimensional; Flow Cytometry; Humans; Image Processing, Computer-Assisted; Isothiocyanates; Molecular Sequence Data; Protein Hydrolysates; Proteins; Proteomics; Seeds; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Trypsin | 2011 |
Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities.
Topics: Acetamides; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Humans; Inhibitory Concentration 50; Leukemia; Mice; Morpholines; NIH 3T3 Cells; Protein Kinase Inhibitors; Pyridines; src-Family Kinases; Structure-Activity Relationship; Thiazoles | 2011 |
Stevens-Johnson Syndrome induced by masitinib.
Topics: Adenocarcinoma; Benzamides; Colonic Neoplasms; Drug Eruptions; Humans; Male; Middle Aged; Piperidines; Protein Kinase Inhibitors; Pyridines; Stevens-Johnson Syndrome; Thiazoles | 2012 |
Aglycon of rhizochalin from the Rhizochalina incrustata induces apoptosis via activation of AMP-activated protein kinase in HT-29 colon cancer cells.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; DNA Fragmentation; Drug Evaluation, Preclinical; Extracellular Signal-Regulated MAP Kinases; Fatty Alcohols; Glycosphingolipids; HT29 Cells; Humans; Mice; Mitogen-Activated Protein Kinases; Molecular Targeted Therapy; Oceans and Seas; Phosphorylation; Phytotherapy; Plant Preparations; Poly(ADP-ribose) Polymerases; Porifera; Protein Serine-Threonine Kinases; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2011 |
Both hMutSα and hMutSß DNA mismatch repair complexes participate in 5-fluorouracil cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Baculoviridae; Cell Line, Tumor; Colonic Neoplasms; Cross-Linking Reagents; DNA Mismatch Repair; DNA-Binding Proteins; Fluorouracil; Humans; Microsatellite Repeats; Oligonucleotides; Recombinant Proteins; Surface Plasmon Resonance; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2011 |
Preparation and in vitro evaluation of meloxicam-loaded PLGA nanoparticles on HT-29 human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Biological Transport; Cell Survival; Chemistry, Pharmaceutical; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Drug Carriers; Drug Stability; HT29 Cells; Humans; Kinetics; Lactic Acid; Meloxicam; Molecular Weight; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Solubility; Surface Properties; Thiazines; Thiazoles | 2012 |
Virosecurinine induces apoptosis by affecting Bcl-2 and Bax expression in human colon cancer SW480 cells.
Topics: Actins; Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Azepines; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Coloring Agents; Euphorbiaceae; Gene Expression; Humans; Lactones; Piperidines; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2012 |
Growth inhibition by caffeic acid, one of the phenolic constituents of honey, in HCT 15 colon cancer cells.
Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Honey; Humans; Membrane Potential, Mitochondrial; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
Inhibition of GSK-3β reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HT29 Cells; Humans; Proadifen; Protein Kinase Inhibitors; Thiazoles; Urea | 2012 |
Supra-additive antitumor activity of 5FU with tumor necrosis factor-related apoptosis-inducing ligand on gastric and colon cancers in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Cell Division; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; HT29 Cells; Humans; Membrane Glycoproteins; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Augmented antitumour effects of combination therapy with TNP-470 and chemoimmunotherapy in mice.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Benzothiazoles; Blotting, Western; Cell Division; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexanes; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Immunotherapy; Interferon-gamma; Interleukin-12; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2002 |
Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer.
Topics: Apoptosis; Cell Division; Cell Survival; Colon; Colonic Neoplasms; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; HT29 Cells; Humans; Hypoglycemic Agents; Immunoenzyme Techniques; Immunologic Factors; Ligands; NF-kappa B; Promoter Regions, Genetic; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic | 2002 |
APC-dependent suppression of colon carcinogenesis by PPARgamma.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cytoskeletal Proteins; Diabetes Mellitus, Type 2; Gene Silencing; Genes, APC; Humans; Hypoglycemic Agents; Male; Mice; Mice, Knockout; Mutation; Receptors, Cytoplasmic and Nuclear; Thiazoles; Trans-Activators; Transcription Factors | 2002 |
A novel mechanism for aspirin-mediated growth inhibition of human colon cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blotting, Western; Cell Cycle; Cell Division; Colonic Neoplasms; Coloring Agents; DNA-Binding Proteins; Dose-Response Relationship, Drug; G1 Phase; Humans; MutS Homolog 3 Protein; Resting Phase, Cell Cycle; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2003 |
Peroxisome proliferator-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxymethane in mice.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Chromans; Colon; Colonic Neoplasms; Female; Immunohistochemistry; Ligands; Mice; Mice, Inbred BALB C; Pioglitazone; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2003 |
4-Substituted 4-hydroxycyclohexa-2,5-dien-1-ones with selective activities against colon and renal cancer cell lines.
Topics: Algorithms; Animals; Antineoplastic Agents; Benzothiazoles; Colonic Neoplasms; Computer Simulation; Cyclohexanes; Cyclohexanones; Drug Screening Assays, Antitumor; Humans; Kidney Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Structure-Activity Relationship; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 2003 |
Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.
Topics: Adenocarcinoma; Antigens, Differentiation; Antigens, Neoplasm; Breast Neoplasms; Caveolin 1; Caveolin 2; Caveolins; Cell Differentiation; Cell Line; Chromans; Colonic Neoplasms; Dimerization; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Kidney; Ligands; Macromolecular Substances; Membrane Microdomains; Neoplasm Proteins; Phenotype; Phenylacetates; Prostaglandin D2; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; RNA, Neoplasm; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone; Tumor Cells, Cultured | 2003 |
Short-chain fatty acids and colon cancer cells: the vitamin D receptor--butyrate connection.
Topics: Alkaline Phosphatase; Blotting, Western; Butyrates; Caco-2 Cells; Calcitriol; Cell Cycle; Cell Differentiation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Regulation; Humans; Receptors, Calcitriol; Thiazoles; Up-Regulation | 2003 |
Cyclin A correlates with the sensitivity of human cancer cells to cytotoxic effects of 5-FU.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cell Line, Tumor; Collagen; Colonic Neoplasms; Coloring Agents; Cyclin A; Dose-Response Relationship, Drug; Flow Cytometry; Fluorouracil; Humans; Immunoblotting; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S Phase; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines.
Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression; Genes, cdc; Genes, Reporter; Humans; Ligands; Luciferases; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Response Elements; RNA, Messenger; Signal Transduction; Thiazoles; Transcription Factors; Transcriptional Activation | 2004 |
Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line.
Topics: Amino Acids; Aminobutyrates; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Colonic Neoplasms; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Excitatory Amino Acid Agonists; Fluorouracil; Humans; Ligands; Organophosphonates; Receptors, Metabotropic Glutamate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Biphasic effect of daidzein on cell growth of human colon cancer cells.
Topics: Alkaline Phosphatase; Caspase 3; Caspases; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Estrogens, Non-Steroidal; Flow Cytometry; G1 Phase; Humans; Isoflavones; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
[Application of meloxicam in scheme of prophylaxis of postoperative complications in patients with an acute ileus of tumoral etiology].
Topics: Acute Disease; Antineoplastic Agents; Colonic Neoplasms; Female; Humans; Ileus; Male; Meloxicam; Neoplasm Staging; Postoperative Complications; Thiazines; Thiazoles | 2004 |
Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor: an in vitro study.
Topics: Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cyclohexanones; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Fibroblasts; Humans; Hypoxia; In Vitro Techniques; Neovascularization, Pathologic; Thiazoles | 2005 |
HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Biomarkers; Breast Neoplasms; Camptothecin; Carcinoma; Colonic Neoplasms; Coloring Agents; Drug Interactions; Drug Resistance, Neoplasm; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression Profiling; Humans; Lung Neoplasms; Paclitaxel; Potassium Channels, Voltage-Gated; Tetrazolium Salts; Thiazoles; Transfection; Vincristine | 2005 |
The patellazoles inhibit protein synthesis at nanomolar concentrations in human colon tumor cells.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Macrolides; Nanotechnology; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Protein Biosynthesis; RNA, Messenger; Structure-Activity Relationship; Thiazoles; Urochordata | 2005 |
Elucidation of thioredoxin as a molecular target for antitumor quinols.
Topics: Amino Acid Sequence; Antineoplastic Agents; Benzothiazoles; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Cyclohexanones; Drug Screening Assays, Antitumor; Humans; Hydroquinones; Insulin; Mass Spectrometry; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Sulfones; Thiazoles; Thioredoxins | 2005 |
Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.
Topics: Anthracenes; Apoptosis; Caspases; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Enzyme Activation; HCT116 Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Thiazoles; Thiazolidines | 2005 |
Characterizations of irofulven cytotoxicity in combination with cisplatin and oxaliplatin in human colon, breast, and ovarian cancer cells.
Topics: Algorithms; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Genes, p53; HT29 Cells; Humans; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2006 |
Activation of PPARgamma is not involved in butyrate-induced epithelial cell differentiation.
Topics: Alkaline Phosphatase; Apoptosis; Butyrates; Caco-2 Cells; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Epithelial Cells; Humans; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones | 2005 |
An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines.
Topics: Animals; Benzothiazoles; Cell Cycle; Cell Line, Tumor; Cells, Cultured; Colonic Neoplasms; Female; Fibroblasts; Humans; Mice; Mitogen-Activated Protein Kinases; NIH 3T3 Cells; Ovarian Neoplasms; Phosphorylation; Radiation Tolerance; Radiation, Ionizing; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2005 |
JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
Topics: Aniline Compounds; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Colonic Neoplasms; Enzyme Activation; Humans; Lung Neoplasms; Microtubules; Mitogen-Activated Protein Kinase 8; Mitosis; Spindle Apparatus; Thiazoles; Thiazolidines | 2005 |
Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.
Topics: Animals; Azoxymethane; Cathepsin E; Colonic Neoplasms; Fatty Acid-Binding Proteins; Ligands; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Perilipin-2; PPAR-beta; RNA, Messenger; Thiazoles | 2006 |
Cyclooxygenase-independent effects of aspirin on HT-29 human colon cancer cells, revealed by oligonucleotide microarrays.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Biotechnology; Cluster Analysis; Colonic Neoplasms; Cyclooxygenase 2; Genome; HT29 Cells; Humans; Microscopy, Electron; Oligonucleotide Array Sequence Analysis; Phylogeny; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Intestinal-specific PPARgamma deficiency enhances tumorigenesis in ApcMin/+ mice.
Topics: Animals; Colonic Neoplasms; Disease Progression; Female; Genes, APC; Genotype; Immunohistochemistry; Intestinal Neoplasms; Male; Mice; Mice, Knockout; Phenotype; PPAR gamma; Sex Factors; Thiazoles; Thiazolidines | 2006 |
Cytotoxic activity of violacein in human colon cancer cells.
Topics: Apoptosis; Caco-2 Cells; Calcium; Caspase 3; Cell Death; Cell Survival; Colonic Neoplasms; Cytochromes c; Enzyme Activation; HT29 Cells; Humans; Indicators and Reagents; Indoles; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2006 |
[Effects of selective and non-selective cyclooxygenase-2 inhibitor on the growth of colon cancer cells].
Topics: Apoptosis; Aspirin; Celecoxib; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Humans; Meloxicam; Pyrazoles; Sulfonamides; Thiazines; Thiazoles | 2006 |
Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents; Benzoquinones; beta-Galactosidase; Cell Line, Tumor; Colonic Neoplasms; Drug Carriers; Drug Delivery Systems; Galactosides; Glycoproteins; HSP90 Heat-Shock Proteins; Humans; Indicators and Reagents; Lactams, Macrocyclic; Mass Spectrometry; Models, Molecular; Prodrugs; Protein Binding; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles | 2006 |
Linker-modified triamine-linked acridine dimers: synthesis and cytotoxicity properties in vitro and in vivo.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA; Humans; Indicators and Reagents; Intercalating Agents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Inbred ICR; Mice, SCID; Nitrogen; Plasmids; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Chaetominine, a cytotoxic alkaloid produced by endophytic Chaetomium sp. IFB-E015.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Campanulaceae; Cell Line, Tumor; Chaetomium; Circular Dichroism; Colonic Neoplasms; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Indole Alkaloids; K562 Cells; Magnetic Resonance Spectroscopy; Plant Leaves; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2006 |
Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib.
Topics: Animals; Cell Adhesion; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Dasatinib; Dose-Response Relationship, Drug; Epithelial Cells; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Leukocytes, Mononuclear; Mice; Mice, Nude; Paxillin; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Thiazoles | 2006 |
Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Diterpenes; DNA Fragmentation; Epoxy Compounds; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; HT29 Cells; Humans; Immunoblotting; Indoles; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2007 |
The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells.
Topics: Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Flow Cytometry; G1 Phase; G2 Phase; Humans; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection; Transketolase | 2007 |
Cellular mechanisms involved in the melatonin inhibition of HT-29 human colon cancer cell proliferation in culture.
Topics: Cell Proliferation; Colonic Neoplasms; Glutathione; Glutathione Peroxidase; Glutathione Reductase; HT29 Cells; Humans; Inhibitory Concentration 50; Kynurenine; Melatonin; Molecular Structure; Receptors, Melatonin; Structure-Activity Relationship; Thiazoles; Thiosemicarbazones | 2007 |
Possible mechanism for the regulation of glucose on proliferation, inhibition and apoptosis of colon cancer cells induced by sodium butyrate.
Topics: Apoptosis; Butyrates; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; Humans; In Situ Nick-End Labeling; Isobutyrates; Oncogene Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2007 |
Comparison of the antivascular and cytotoxic activities of TZT-1027 (Soblidotin) with those of other anticancer agents.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Colonic Neoplasms; Dextrans; Diffusion; Endothelial Cells; Endothelium, Vascular; Female; Fluorescein-5-isothiocyanate; Humans; Indicators and Reagents; Mice; Mice, Inbred BALB C; Oligopeptides; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2007 |
Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.
Topics: Animals; Cell Division; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Ligands; Mice; Mice, Knockout; PPAR delta; PPAR-beta; Signal Transduction; Sulfonamides; Thiazoles | 2008 |
Active nanodiamond hydrogels for chemotherapeutic delivery.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Cell Line, Tumor; Colonic Neoplasms; Diamond; Doxorubicin; Drug Delivery Systems; Humans; Macrophages; Mice; Nanoparticles; Nanotechnology; Neoplasms; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2007 |
Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; HCT116 Cells; Histone Deacetylase Inhibitors; Humans; Male; Membrane Potentials; Mice; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Messenger; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53 | 2007 |
Isolation and characterization of new lactam compounds that inhibit lung and colon cancer cells from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) bran.
Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Coix; Colonic Neoplasms; HT29 Cells; Humans; Lactams; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Blotting, Western; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Colony-Forming Units Assay; Cyclin-Dependent Kinases; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Mice; Mice, Nude; Mice, SCID; Phosphorylation; Retinoblastoma Protein; Thiazoles; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2008 |
Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Colonic Neoplasms; ErbB Receptors; Fibroblasts; Genistein; Humans; Hydroxylation; Isoflavones; Mice; Molecular Structure; Protein-Tyrosine Kinases; Quercetin; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 1994 |
The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Infusions, Parenteral; Leucovorin; Male; Mice; Mice, Inbred Strains; Mice, Nude; Models, Biological; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |
Significance of in vitro attachment of human colon cancers to extracellular matrix proteins in experimental and clinical liver metastases.
Topics: Animals; Cell Adhesion; Cell Line; Colonic Neoplasms; Coloring Agents; Extracellular Matrix Proteins; Humans; Liver Neoplasms; Male; Mice; Mice, SCID; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Novel doxorubicin-monoclonal anti-carcinoembryonic antigen antibody immunoconjugate activity in vitro.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Carcinoembryonic Antigen; Cell Survival; Colonic Neoplasms; Doxorubicin; Humans; Immunotoxins; Sulfhydryl Reagents; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
In vitro cytotoxicity and immunomodulating property of Rhaphidophora korthalsii.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Coloring Agents; Concanavalin A; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Leukemia P388; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Nasopharyngeal Neoplasms; Plant Extracts; Plant Lectins; Plants, Medicinal; Spleen; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Water | 1996 |
Increased L-arginine transport in a nitric oxide-producing metastatic colon cancer cell line.
Topics: Adenocarcinoma; Arginine; Biological Transport; Cell Division; Cell Membrane; Colonic Neoplasms; Coloring Agents; Dexamethasone; Glucocorticoids; Humans; Hydrogen-Ion Concentration; Kinetics; Lymphatic Metastasis; Nitric Oxide; Sodium; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Up-Regulation | 1996 |
Comparative study of classical, colorimetric and immunologic staining methods for the assessment of tumor cell viability.
Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Colonic Neoplasms; Colorimetry; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Mitochondria; Spectrophotometry; Staining and Labeling; Tetrazolium Salts; Thiazoles; Trypan Blue | 1996 |
Cell line specific radiosensitizing effect of zalcitabine (2',3'-dideoxycytidine).
Topics: Breast Neoplasms; Cell Cycle; Colonic Neoplasms; Flow Cytometry; Humans; Radiation-Sensitizing Agents; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Zalcitabine | 1997 |
Apoptosis in cultured human colon cancer cells induced by combined treatments with 5-fluorouracil, tumor necrosis factor-alpha and interferon-alpha.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azure Stains; Cell Survival; Colonic Neoplasms; Coloring Agents; DNA Nucleotidylexotransferase; Fluorouracil; Humans; Interferon-alpha; Methyl Green; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Structure-activity of novel rhodacyanine dyes as antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Crystallography, X-Ray; Humans; KB Cells; Mice; Mice, Inbred Strains; Mice, Nude; Molecular Structure; Structure-Activity Relationship; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
2-(4-Aminophenyl)benzothiazoles: novel agents with selective profiles of in vitro anti-tumour activity.
Topics: Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Carcinoma; Cell Cycle; Colonic Neoplasms; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Estrogens; Female; Growth Inhibitors; Humans; Kidney Neoplasms; Male; Melanoma; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Skin Neoplasms; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 1998 |
Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Colonic Neoplasms; Dactinomycin; Doxorubicin; Drug Resistance, Multiple; Gene Expression Regulation; Genes, MDR; Genes, ras; Insulin-Like Growth Factor I; Lovastatin; Mice; Mitochondria; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Inhibition by platelet-activating factor of Src- and hepatocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells. Phosphatidylinositol 3'-kinase is a critical mediator of tumor invasion.
Topics: Androstadienes; Animals; Azepines; Cell Adhesion Molecules; Cell Movement; Chromones; Colonic Neoplasms; Dogs; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Genes, src; GTP-Binding Proteins; Hepatocyte Growth Factor; Humans; Intestinal Mucosa; Kidney; Morpholines; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Thiazoles; Transformation, Genetic; Triazoles; Tumor Cells, Cultured; Virulence Factors, Bordetella; Wortmannin | 1998 |
Differentiation and reversal of malignant changes in colon cancer through PPARgamma.
Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Division; Chromans; Colonic Neoplasms; Gene Expression; Humans; Ligands; Mice; Mice, Nude; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 1998 |
Selective antitumor activity of MKT-077, a delocalized lipophilic cation, on normal cells and cancer cells in vitro.
Topics: Antineoplastic Agents; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; In Vitro Techniques; Inhibitory Concentration 50; Male; Pancreatic Neoplasms; Pyridines; Spleen; Stomach Neoplasms; Thiazoles; Tumor Cells, Cultured | 1998 |
Antiproliferative effect of carotenoids on human colon cancer cells without conversion to retinoic acid.
Topics: Carotenoids; Cell Division; Cell Survival; Colonic Neoplasms; Coloring Agents; Humans; Receptors, Retinoic Acid; Tetrazolium Salts; Thiazoles; Tretinoin; Tumor Cells, Cultured; Vitamin A | 1998 |
Pharmacokinetic analysis and antitumor efficacy of MKT-077, a novel antitumor agent.
Topics: Animals; Antineoplastic Agents; Autoradiography; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Mice; Mice, Nude; Pyridines; Thiazoles; Tissue Distribution; Transplantation, Heterologous | 1999 |
Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells.
Topics: Calcium-Binding Proteins; Carrier Proteins; Cell Differentiation; Cell Division; Chromans; Colonic Neoplasms; Genes, Reporter; Humans; Luciferases; Microfilament Proteins; Nuclear Proteins; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Troglitazone; Tumor Cells, Cultured | 1999 |
In vitro augmentation of antitumor effect in combination with CPT-11 and CDDP for human colorectal cancer.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Coloring Agents; Drug Synergism; Female; Humans; Irinotecan; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs.
Topics: Antineoplastic Agents; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Doxorubicin; Drug Interactions; Epoxy Compounds; Humans; Microtubules; Mutagens; Paclitaxel; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vinblastine | 2000 |
A needle-type immunotherapeutic system incorporating laser light and platonin in combination with ethanol injection in the treatment of cancer growing in deep organs.
Topics: Animals; Colonic Neoplasms; Coloring Agents; Ethanol; Immunotherapy; Injections; Lasers; Lymphocytes; Macrophage Activation; Male; Mice; Mice, Inbred Strains; Needles; Neoplasms, Experimental; Photosensitizing Agents; Quinolinium Compounds; Survival Rate; Thiazoles | 1999 |
Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives.
Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Hydroquinones; Oxidation-Reduction; Thiazoles; Tumor Cells, Cultured | 2000 |
The antiproliferative effects of melatonin on experimental pituitary and colonic tumors. Possible involvement of the putative nuclear binding site?
Topics: Animals; Cell Division; Cell Nucleus; Colonic Neoplasms; Diethylstilbestrol; Male; Melatonin; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pituitary Neoplasms; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Thiazoles; Thiosemicarbazones | 1999 |
Effect of the specific cyclooxygenase-2 inhibitor meloxicam on tumour growth and cachexia in a murine model.
Topics: Adenocarcinoma; Animals; Body Weight; Cachexia; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Isoenzymes; Male; Meloxicam; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Prostaglandin-Endoperoxide Synthases; Thiazines; Thiazoles; Time Factors | 2000 |
Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells.
Topics: Alkaloids; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Butyrates; Carcinoma; Cell Nucleus; Colonic Neoplasms; Coloring Agents; Cyclic P-Oxides; Cytoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Microscopy, Fluorescence; Neoplasm Proteins; Nicotinic Acids; RNA, Catalytic; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles | 2001 |
Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Bezafibrate; Cell Division; Chromans; Colitis; Colonic Neoplasms; Dextran Sulfate; Growth Substances; Intestinal Mucosa; Ligands; Male; Mucins; Muscle Proteins; Neuropeptides; Nucleolus Organizer Region; Peptides; Precancerous Conditions; Proteins; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Silver Staining; Thiazoles; Thiazolidinediones; Transcription Factors; Trefoil Factor-2; Trefoil Factor-3; Troglitazone | 2001 |
Troglitazone, a ligand for peroxisome proliferator-activated receptor gamma, inhibits chemically-induced aberrant crypt foci in rats.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Biogenic Polyamines; Carcinogens; Chromans; Colitis; Colonic Neoplasms; Dextran Sulfate; Intestinal Mucosa; Ligands; Male; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Survival; Colonic Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Female; Humans; Infusions, Parenteral; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Pancreatic Neoplasms; Sarcoma; Thiazoles; Tubulin; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2001 |
Bispecific antibody targeting of doxorubicin to carcinoembryonic antigen-expressing colon cancer cell lines in vitro and in vivo.
Topics: Animals; Antibodies, Bispecific; Antineoplastic Agents; Carcinoembryonic Antigen; Cell Survival; Colonic Neoplasms; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Flow Cytometry; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Polyethylene glycol induces apoptosis in HT-29 cells: potential mechanism for chemoprevention of colon cancer.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Cell Division; Cell Separation; Cell Survival; Colonic Neoplasms; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; HT29 Cells; Humans; Intracellular Signaling Peptides and Proteins; Polyethylene Glycols; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Prodigiosin-induced apoptosis in human colon cancer cells.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Apoptosis; Benzimidazoles; Caspases; Cell Survival; Colonic Neoplasms; DNA; Drug Screening Assays, Antitumor; Enzyme Activation; Fluorescent Dyes; Humans; Mice; Prodigiosin; Serratia marcescens; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.
Topics: Adenocarcinoma; Alleles; Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzothiazoles; Butyrates; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Demecolcine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Neoplasm Proteins; Recombination, Genetic; Resveratrol; Stilbenes; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Reversal of cisplatin and multidrug resistance by ribozyme-mediated glutathione suppression.
Topics: Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glutamate-Cysteine Ligase; Glutathione; Humans; RNA, Catalytic; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Melatonin and RZR/ROR receptor ligand CGP 52608 induce apoptosis in the murine colonic cancer.
Topics: Animals; Apoptosis; Colonic Neoplasms; Ligands; Male; Melatonin; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Thiazoles; Thiosemicarbazones | 2001 |
Synthesis, in vitro and in vivo cytotoxicity, and prediction of the intestinal absorption of substituted 2-ethoxycarbonyl-imidazo[2,1-b]benzothiazoles.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Drug Evaluation, Preclinical; Humans; Intestinal Absorption; Lung Neoplasms; Mice; Molecular Structure; Neoplasm Transplantation; Software; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 2001 |
Antiproliferative activity of mixed-ligand dien-Cu(II) complexes with thiazole, thiazoline and imidazole derivatives.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Cycle Proteins; Cell Division; Colonic Neoplasms; Copper; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Imidazoles; Ligands; Molecular Structure; Organometallic Compounds; Polyamines; Spectrum Analysis; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 2002 |
Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells.
Topics: Apoptosis; Cell Division; Cell Survival; Chromans; Colonic Neoplasms; DNA, Complementary; DNA, Neoplasm; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Ligands; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
Malevamide D: isolation and structure determination of an isodolastatin H analogue from the marine cyanobacterium Symploca hydnoides.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyanobacteria; Depsipeptides; Drug Screening Assays, Antitumor; Hawaii; Hydrolysis; Inhibitory Concentration 50; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Stereoisomerism; Thiazoles; Tumor Cells, Cultured | 2002 |
Decreased synthesis of matrix metalloproteinase-7 and adhesion to the extracellular matrix proteins of human colon cancer cells treated with troglitazone.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Adhesion; Cell Division; Chromans; Collagen Type I; Colonic Neoplasms; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix Proteins; Fibronectins; Flow Cytometry; Humans; Integrins; Laminin; Matrix Metalloproteinase 7; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2002 |
MTT assays allow quick and reliable measurement of the response of human tumour cells to photodynamic therapy.
Topics: Adenocarcinoma; Breast Neoplasms; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Hematoporphyrin Derivative; Hematoporphyrins; Humans; Photochemotherapy; Radiation-Sensitizing Agents; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Activity of two platinum-linked phosphonic acids against autochthonous rat colorectal cancer as well as in two human colon-cancer cell lines.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Humans; Male; Organophosphonates; Organophosphorus Compounds; Organoplatinum Compounds; Rats; Rats, Inbred Lew; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
[Comparison between clinical response and in vitro chemosensitivity of solid tumors in the succinic dehydrogenase inhibition test].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies; Stomach Neoplasms; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Expression of MDR1 and glutathione S transferase-pi genes and chemosensitivities in human gastrointestinal cancer.
Topics: Adenocarcinoma; Blotting, Northern; Cell Line; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Resistance; Glutathione Transferase; Humans; Nucleic Acid Hybridization; RNA, Messenger; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 1992 |
Increased drug resistance of cultured human cancer cell lines in three-dimensional cellular growth assay using collagen gel matrix.
Topics: Adenocarcinoma; Antineoplastic Agents; Cisplatin; Collagen; Colonic Neoplasms; Culture Media; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mitomycin; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon.
Topics: Acetylcysteine; Allyl Compounds; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Dehydroepiandrosterone; Eflornithine; Ellagic Acid; Isothiocyanates; Male; Precancerous Conditions; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfides; Thiazoles; Thiazolidines; Thiocyanates | 1991 |
The influence of stromal cells on the MTT assay (II)--Study on the nude mouse system.
Topics: Animals; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Nude; Mitomycin; Mitomycins; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 1991 |
[Establishment of transplantable human colon cancer cell lines, chemosensitivity of colon carcinomas and the serially transplantable strains with MTT assay].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Inhibition of ribonucleotide reductase and growth of human colon carcinoma HT-29 cells and mouse leukemia L1210 cells by N-hydroxy-N'-aminoguanidine derivatives.
Topics: Animals; Cell Division; Cell-Free System; Colonic Neoplasms; Guanidines; Humans; Leukemia L1210; Mice; Ribonucleotide Reductases; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1990 |
Comparison of tetrazolium colorimetric and [3H]-uridine assays for in vitro chemosensitivity testing.
Topics: Carcinoma; Cell Line; Colonic Neoplasms; Colorimetry; Coloring Agents; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Immunoglobulin G; Immunotoxins; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tritium; Tumor Cells, Cultured; Uridine; Uterine Cervical Neoplasms; Vindesine | 1989 |
Synthesis and antineoplastic activity of 5-aryl-2,3-dihydropyrrolo[2,1-b]thiazole-6,7-dimethanol 6,7-bis(isopropylcarbamates).
Topics: Carbamates; Cell Division; Cell Survival; Chemical Phenomena; Chemistry; Colonic Neoplasms; Humans; Leukemia, Myeloid; Neoplasms; Pyrroles; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 1988 |
Comparison of in vitro activity of cytotoxic drugs towards human carcinoma and leukaemia cell lines.
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Cell Count; Cell Line; Cell Survival; Colonic Neoplasms; Humans; Kinetics; Leukemia; Tetrazolium Salts; Thiazoles | 1986 |