Page last updated: 2024-08-21

thiazoles and Breast Neoplasms

thiazoles has been researched along with Breast Neoplasms in 361 studies

Research

Studies (361)

TimeframeStudies, this research(%)All Research%
pre-19903 (0.83)18.7374
1990's31 (8.59)18.2507
2000's108 (29.92)29.6817
2010's160 (44.32)24.3611
2020's59 (16.34)2.80

Authors

AuthorsStudies
Kanno, Y; Kizu, R; Ozawa, M; Sanada, N; Taga, C; Yamashita, N1
Fu, A; Huang, R; Liang, J; Tang, M; Wang, L; Zhou, J1
Balic, M; Bartsch, R; Dandachi, N; Gerritsmann, H; Graf, R; Heitzer, E; Jahn, S; Jost, PJ; Kashofer, K; Klocker, EV; Lindenmann, J; Posch, F; Regitnig, P; Suppan, C; Terbuch, A; Zhou, Q1
Chen, C; Chen, X; Chi, L; Guo, X; Guo, Z; He, J; Liang, J; Wei, L; Ye, X; Zheng, Y1
Chin, CM; Scarim, CB1
Cheung, YM; Cromwell, GE; McDonnell, ME; Min, L; Tolaney, SM1
Aapro, MS; Goncalves, MD; Lacouture, ME; Masharani, U; O'Shaughnessy, JA; Rugo, HS1
Jacobson, A1
Adam, V; Bedard, PL; Carrasco, E; Criscitiello, C; Di Leo, A; Pérez-Fidalgo, JA; Regan, MM; Ribi, K1
Abdel-Aziz, HA; Abdelmoaz, MA; Al-Warhi, T; Albohy, A; Aljaeed, N; El Kerdawy, AM; Eldehna, WM; Elkaeed, EB; Elsayed, ZM; Said, MA1
Eisner, JR; Lerner, LM; Michmerhuizen, AR; Pesch, AM; Pierce, LJ; Rae, JM; Schwartz, R; Speers, CW; Ward, C; Wilder-Romans, K; Zhang, A1
Blackley, EF; Bujak, AZ; Callahan, J; Dawson, SJ; Francis, PA; Ftouni, S; Hicks, RJ; Ko, YA; Lee, CK; Lo, LL; Loi, S; Luen, SJ; Moodie, K; Savas, P; Silva, MJ; van Geelen, CT; Wein, L; Weng, CF; Yeung, MM1
Alessandrini, G; Blandino, G; Botti, C; Carosi, M; Ciliberto, G; Cioce, M; Daralioti, T; Di Martino, S; Donzelli, S; Fazio, VM; Goeman, F; Orlandi, G; Piccolo, S; Sacconi, A; Strano, S; Telera, S; Zanconato, F1
Fan, X; Jiang, Z; Li, M; Lu, Q; Yu, Q; Zhang, L; Zhao, W; Zhu, Y1
Bauer, M; Climova, A; Czylkowska, A; Dzięgielewski, M; Jóźwiak, P; Kamysz, W; Krześlak, A; Pivovarova, E; Staszewski, M; Świątkowski, M; Walczyński, K1
Kaderbhaï, CG; Royer, B; Schmitt, A1
Huang, Z; Li, J; Lou, C; Ye, Y; Zhang, M; Zhang, Y1
Park, J; Shin, SW1
Copur, MS; Jonglertham, P1
André, F; Mills, D; Taran, T1
Melegari, E; Palleschi, M; Rocca, A1
Aschenbrenner, DS1
Antoine, A; Baselga, J; Cantley, LC; Chandarlapaty, S; Chang, MT; Dickler, MN; Friedman, LS; Gorelick, A; Jhaveri, K; Johnson, JL; Kazmi, A; Ladewig, E; Lin, TY; Rabadan, R; Razavi, P; Reznik, E; Scaltriti, M; Schimmoller, F; Sebra, R; Shah, H; Shao, H; Smith, ML; Taylor, BS; Toska, E; Vasan, N; Wilson, TR; Xu, G1
Jin, G; Liu, X; Liu, Y; Wang, K; Zhang, H; Zhang, X1
Adler, B; Bass, IR; Gallagher, EJ; Ryncarz, A; Tiersten, A; Trlica, K1
Hirao-Suzuki, M; Koga, T; Takeda, S; Takiguchi, M; Toda, A1
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; Taratkin, M; Teijeira, Á; Tellew, JE; Thomas, AM; Thomas, SG; Thomson, SR; Tian, J; Tie, Y; Tirado, JL; Tolonen, A; Tosato, G; Tronnet, A; Tsai, S; Turtoi, A; Turtoi, E; Tvrdoňová, M; Tyagi, A; Tzou, DT; Uddin Ahmad, Z; Urias, E; Usawachintachit, M; Ustriyana, P; Utsumi, F; Vacca, M; Vaculovič, T; Vaidya, SS; Valentin, A; Valgepea, K; van den Berg, P; van den Bergh, JP; van der Heiden, K; van Gaalen, K; Van Gemert, W; van Haard, PMM; van Hest, JCM; Vecchiarelli, E; Večeřa, Z; Venkatesh, R; Verhaeghe, P; Verhagen, HJ; Vetter, JM; Vieira, D; Vilchez-Tschischke, JP; Villena-Gutierrez, R; Villoslada Terrones, V; Vital-Jacome, M; Voelkl, J; Vogel, K; Vogrin, S; Volke, D; von Bahr, V; Vysloužil, J; Wade, TL; Wagner-Gillespie, M; Walsh, SW; Wan, LJ; Wan, SP; Wang, AL; Wang, B; Wang, BY; Wang, C; Wang, D; Wang, F; Wang, H; Wang, HR; Wang, HY; Wang, J; Wang, JY; Wang, K; Wang, L; Wang, LF; Wang, P; Wang, Q; Wang, R; Wang, SF; Wang, SP; Wang, SR; Wang, T; Wang, W; Wang, WP; Wang, X; Wang, XJ; Wang, Y; Wang, YL; Wang, YN; Wáng, YXJ; Wang, Z; Wang, ZF; Wang, ZY; Waning, B; Warner, JM; Washington, SL; Watson, AK; Wei, B; Wei, C; Wei, F; Wei, X; Wei, Y; Wemhoff, AP; Wen, Z; Weng, TT; Wesdemiotis, C; Wheeler, DA; Wildner, M; Wilson, BK; Wirth, LJ; Wissler, M; Wu, F; Wu, G; Wu, J; Wu, KH; Wu, MC; Wu, P; Wu, PK; Wu, S; Wu, W; Wu, X; Wu, XP; Wu, Y; Wyatt, E; Wyllie, S; Xia, Y; Xiao, BH; Xiao, SZ; Xiao, W; Xiao, X; Xiao, Z; Xie, D; Xie, K; Xie, X; Xie, Y; Xie, YF; Xin, S; Xin, Z; Xing, Q; Xing, WQ; Xiong, D; Xiong, X; Xu, C; Xu, D; Xu, F; Xu, G; Xu, H; Xu, J; Xu, JY; Xu, L; Xu, N; Xu, W; Xu, X; Xu, Y; Xu, YM; Xue, H; Xue, J; Xue, Z; Yan, R; Yan, SQ; Yan, W; Yan, X; Yan, Z; Yang, C; Yang, D; Yang, F; Yang, FC; Yang, G; Yang, J; Yang, M; Yang, P; Yang, Q; Yang, R; Yang, S; Yang, SJ; Yang, TWW; Yang, X; Yang, Y; Yang, Z; Yao, C; Yao, L; Yao, LP; Yao, M; Yao, T; Yao, W; Yao, Y; Yaseen, T; Yazdani, V; Ye, J; Ye, S; Yerys, BE; Yi, HWL; Yi, JL; Yin, F; Yin, J; Yin, Y; Yin, Z; Yong, ZP; Yongli, S; Yoo, JS; 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Almeida, J; Bandarra, D; Brandão, P; Calhorda, MJ; Félix, V; Lopes, M; Lopes, T; Meireles, M; Nunes, CD; Saraiva, MS; Vasconcellos-Dias, M; Vaz, PD1
Abrantes, AM; Beja, AM; Botelho, MF; Brito, AF; Laranjo, M; Paixão, JA; Pinho E Melo, TM; Silva, MR; Soares, MI1
Montero, JC; Ocaña, A; Pandiella, A; Seoane, S1
Berdyshev, E; Leclercq, T; Lim, KG; Long, JS; Loveridge, C; Natarajan, V; Pitson, SM; Pyne, NJ; Pyne, S; Tate, RJ; Tonelli, F1
Kanomata, N; Kozuka, Y; Kurebayashi, J; Moriya, T; Sonoo, H; Watanabe, M1
Azodi, M; Chambers, SK; Lamb, T; Roy, WJ; Toy, EP; Woo, HH1
Al-Qasoumi, SI; Al-Said, MS; Bashandy, MS; Ghorab, MM1
Chakravarty, D; Challa, R; Cortez, V; Nair, BC; Tekmal, RR; Vadlamudi, RK; Vallabhaneni, S1
Antoon, JW; Ashe, HB; Beckman, BS; Bratton, MR; Burow, ME; Meacham, WD; Rhodes, LV; Slaughter, EM; Wiese, TE1
Collins, DM; Corkery, B; Crown, J; Duffy, MJ; Evoy, D; Flanagan, L; McDermott, EW; O'Donovan, N; Pierce, A; Quinn, C; Tryfonopoulos, D; Walsh, S1
Abbruzzi, A; Bromberg, J; Chang, J; D'Andrea, G; Dang, C; Dickler, M; Fornier, MN; Gilewski, T; Hudis, CA; Modi, S; Morris, PG; Norton, L; Seidman, AD; Sklarin, N1
Cheyne, RW; McLaughlin, A; Smith, TA; Trembleau, L1
Bensdorf, K; Cai, X; Cao, P; Gust, R; Huang, W; Li, Z; Liu, W; Qi, F; Qian, H; Wellner, A; Zhang, H; Zhou, J1
Bareford, MD; Cruickshanks, N; Dai, Y; Dent, P; Grant, S; Hamed, HA; Hubbard, N; Mitchell, C; Tang, Y; Tye, G; Yacoub, A1
Allen, JD; Alling, N; Haass, NK; Jackson, EA; Martinello-Wilks, R; McGowan, EM; Yagoub, D1
Flomenberg, N; Goldberg, AF; Howell, A; Ko, YH; Lin, Z; Lisanti, MP; Martinez-Outschoorn, UE; Pavlides, S; Pestell, RG; Sotgia, F; Wang, C1
Bacus, S; Blackwell, KL; Chadaram, V; Favaro, J; Hamilton, E; Herold, CI; Hopkins, J; Kimmick, GG; Marcom, PK; Peterson, BL; Welch, RA1
Cho, SH; Hwang, SY; Lee, BH; Lee, EK; Song, YJ1
Bradshaw, TD; Choo, HL; Leong, CO; Muruhadas, A; Randhawa, N; Stevens, MF; Tan, BS; Tiong, KH1
Akbarzadeh, T; Bu, Y; Fallah-Tafti, A; Foroumadi, A; Hangauer, DG; Parang, K; Shafiee, A; Shirazi, AN; Tiwari, R1
Arshad Siddiqui, M; Belanger, DB; Bracken, JB; Curran, PJ; Malkowski, M; Miao, H; Shipps, GW; Wang, Y; Zeng, H1
Edgerton, SM; Fan, Z; Lind, SE; Liu, B; Thor, AD; Yang, X1
El-Hazek, RM; Ghorab, MM; Heiba, HI; Ragab, FA1
Awada, A; Baurain, JF; Campone, M; Fumoleau, P; Llombart-Cussac, A; Mayer, EL; Rugo, H; Sparano, J; Strauss, L; Sy, O1
Cui, M; Ji, M; Li, X; Liu, S; Lou, H; Xie, W; Zhang, Y1
Fair, PA; Henry, ND1
Cheyne, RW; Smith, TA1
Iwase, S; Kitamura, K; Kuroda, Y; Nagumo, Y; Odagiri, H; Yamamoto, C; Yamamoto, D; Yoshida, H1
Bugyik, E; Dezso, K; Döme, B; Klepetko, W; László, V; Nagy, P; Paku, S; Reiniger, L; Tímár, J; Tóvári, J1
Chen, X; Li, E; Liu, S; Liu, X; Zhang, H; Zheng, Z; Zou, X1
Chang, CY; Jasper, JS; Kazmin, D; Kunder, R; McDonnell, DP; Zuercher, WJ1
Bengala, C; Fairchild, J; Finn, RS; Goldstein, LJ; Ibrahim, N; Roché, H; Sparano, J; Strauss, LC; Sy, O1
Ahmed, EM; Khalil, NA; Taher, AT1
Baergen, RN; Boeck, M; Christos, P; Chuang, E; Cigler, T; Cobham, MV; Donovan, D; Jain, S; Lam, C; Lane, ME; Mittal, V; Moore, A; O'Loughlin, J; Rafii, S; Schneider, S; Swistel, A; Vahdat, LT; Ward, MM; Wiener, N1
Corey, SJ; Park, BJ; Whichard, ZL1
Azevedo-Silva, J; Baltazar, F; Casal, M; Ko, YH; Moreira, R; Pacheco, A; Pedersen, PL; Pedro, M; Pinheiro, C; Preto, A; Queirós, O1
Chen, X; Li, H; Niu, J; Ping, Q; Xiao, Y1
Liu, J; Liu, Y; Ma, Y; Zhang, J; Zhang, S; Zhang, X; Zhu, Y1
Antoon, JW; Beckman, BS; Burow, ME; White, MD1
Calcabrini, A; Gómez-Domínguez, D; Gómez-López, G; Martín-Forero, E; Martín-Pérez, J; Molinari, A; Morte, B; Sánchez-Bailón, MP; Wagner, KU1
Braun, RD; Chunta, JL; Vistisen, KS; Yazdi, Z1
Blencke, S; Godl, K; Kaminski, M; Klammer, M; Marx, S; Müller, S; Oppermann, F; Schaab, C; Tebbe, A; Zedler, A1
Aarts, M; Ashworth, A; Garcia-Murillas, I; Gevensleben, H; Hurd, MS; Sharpe, R; Shumway, SD; Toniatti, C; Turner, NC1
Chakraborti, S; Gireesh, KK; Manna, T; Panda, D; Rashid, A1
Ali, A; Anbalagan, M; Bu, Y; Carrier, L; Hangauer, D; Jones, RK; Marsden, CG; Rowan, BG; Sheng, M1
Forinash, KD; Lawrence, NJ; Martin, MP; Patel, RA; Pireddu, R; Schönbrunn, E; Sebti, SM; Sun, N; Sun, Y1
Airley, R1
Antoon, JW; Beckman, BS; Burow, ME; Driver, JL; White, MD1
Aktas, BH; Chen, L; Chorev, M; Denoyelle, S; Freedman, RY; Halperin, JA; He, X; Kabha, E; Sahoo, R; Supko, JG; Wagner, G; Wang, Y; Yang, H; Zhang, N1
Kubisch, R; Liebl, J; Müller, R; Palamidessi, A; Schempp, C; Schreiner, L; Scita, G; Trauner, D; Vereb, G; Vollmar, AM; von Schwarzenberg, K; Wagner, E; Wiedmann, RM; Zahler, S1
Huang, J; Mao, W; Shen, Y; Sui, M; Wang, J; Wu, X; Zhang, H1
Botelho, MF; Brito, AF; Laranjo, M; Paixão, JA; Pinho e Melo, TM; Soares, MI1
Chauvier, D; Kegelaer, G; Manfait, M; Morjani, H1
Arslanian, RL; Blough, S; Carney, JR; Katz, L; Ma, W; Qiu, RG; Tang, L1
Goker, E; Karabulut, B; Omay, SB; Sanli, UA; Saydam, G; Sezgin, C; Uslu, R1
Boven, E; Hoogsteen, IJ; Kohlhagen, G; Maliepaard, M; Pinedo, HM; Pommier, Y; Scheffer, GL; Scheper, RJ; Schlüper, HM; van Hattum, AH1
Connelly, J; Harris, E; Hose, C; Monks, A; Sausville, EA1
Burghardt, R; Qin, C; Safe, S; Smith, R; Stewart, J; Wormke, M1
Kim, R; Murakami, S; Toge, T1
Hewitt, LM; MacLean, DD; McMaster, ME; Munkittrick, KR; Oakes, KD; Portt, CB; Pryce, AC; Van Der Kraak, GJ1
Burgermeister, E; Liscovitch, M; Tencer, L1
Dawson, MI; James, SY; Kolluri, SK; Lin, F; Zhang, XK1
Burstein, HJ; Demetri, GD; Mueller, E; Sarraf, P; Spiegelman, BM; Winer, EP1
Casero, RA; Davidson, NE; Dunn, VR; Frydman, B; Hacker, A; Hager, ER; Huang, Y; Kink, JA; Marton, LJ; Phillips, DL; Reddy, VK; Valasinas, AL1
Gong, L; Li, Y; Nedeljkovic-Kurepa, A; Sarkar, FH1
Botella, L; Cabello, G; Calaf, G; Cañete, M; Galaz, S; Juarranz, A; Pacheco, M; Stockert, JC; Villanueva, A1
Albanese, C; Brownlee, M; Donehower, LA; Fu, M; Harris, EL; Hulit, J; Johns, DC; Jones, JG; Li, Z; Neumeister, P; Novikoff, PM; Pattabiraman, N; Pestell, RG; Rohan, T; Sakamaki, T; Scherer, PE; Wang, C; Whitney, KD; Wu, K; Zhou, JN1
Bradshaw, TD; Browne, HL; Laughton, CA; O'Brien, SE; Stevens, MF; Westwell, AD1
Cocca, C; Perez-Castillo, A; Pignatelli, M; Santos, A1
Aouali, N; Giroux, B; Manfait, M; Morjani, H; Soma, E; Trussardi, A1
FALKSON, G; FALKSON, HC1
Atadja, P; Bali, P; Bhalla, K; Donapaty, S; Fuino, L; Guo, F; Wang, HG; Wittmann, S; Yamaguchi, H1
Appella, E; Fan, YX; Farrar, WL; Howard, OM; Maynard, AT; Mihalic, K; Wang, LH; Xiao, W; Yang, XY; Zhang, X1
Abraham, SA; Bally, MB; Harasym, TO; Masin, D; Mayer, LD; McKenzie, C; Ng, R1
Brown, ML; Bushweller, JH; Gorczynski, MJ; Leal, RM; Mooberry, SL1
Foley, DA; Hill, AK; McDermott, EW; O'Higgins, NJ; Teh, SH; Young, LS1
Cherian, MG; Ostrakhovitch, EA1
Brugge, JS; Daley, GQ; Koh, EY; Leder, P; Lu, Y; Martin, SS; Michelman, M; Pinkas, J; Reginato, MJ; Ridgeway, AG1
Bally, MB; Chia, S; Denyssevych, T; Dragowska, WH; Gelmon, K; Masin, D; Wallis, AE; Warburton, C; Yan, H1
Ehrenborg, E; Gustafsson, MC; Harris, AL; Jarvis, M; Knight, D; Marshall, BR; Palmer, CN; Stephen, RL; Tatoud, R; Wolf, CR1
Barrett, JT; Delk, JN; Gaddy, VT; Kallab, AM; Porter, AG; Schoenlein, PV1
Bradshaw, TD; Fichtner, I; Hose, C; Monks, A; Stevens, MF1
Bergman, A; Bohonowych, J; Denison, MS; Peters, AK; Sanderson, JT; van den Berg, M; van Londen, K1
Carnio, L; Hannigan, GE; Johnstone, CN; Leung-Hagesteijn, C; Mongroo, PS; Naruszewicz, I; Rustgi, AK; Sung, RK1
Guerrero, JM; Leon-Blanco, MM; Pozo, D; Reiter, RJ1
Cao, Y; Fernandez-Luna, JL; Nikolovska-Coleska, Z; Real, PJ; Sanz-Ortiz, J; Wang, R; Wang, S1
Kozubík, A; Machala, M; Plísková, M; Vojtesek, B; Vondrácek, J1
Cao, X; Chen, G; Chen, T; Li, N; Wan, T; Wang, C; Wang, T; Xia, D1
Adachi, Y; Schinkel, AH; Sugiyama, Y; Suzuki, H1
Cress, WD; Freeman, SN; Ma, Y1
Bibby, MC; Bradshaw, TD; Leong, CO; Stevens, MF; Suggitt, M; Swaine, DJ1
Bradshaw, TD; Carmichael, J; Martin, SG; Mukherjee, A; Stevens, MF; Westwell, AD1
Ando, K; Chang, YC; Furukawa, C; Magae, J; Mizuta, N; Nakajima, H; Ozawa, S; Sakaguchi, K; Yamagishi, H1
Borojević, N; Jovanović, D; Juranić, ZD; Milosević, D; Nesković-Konstantinović, Z; Raonić, T; Sarić, M; Stanojević-Bakić, N; Stanojković, T; Zizak, Z1
Chen, SZ; Jiang, M; Zhen, YS1
Bailey, K; Bradshaw, TD; Chew, EH; Cookson, J; Harris, E; Laughton, CA; Matthews, CS; Monks, A; Shah, M; Stevens, MF; Wells, G; Westwell, AD1
Debeir, O; Decaestecker, C; Hayot, C; Kiss, R; Van Damme, M; Van Ham, P1
Calvo, F; Cvitkovic, E; Koeppel, F; Laar, ES; Larsen, AK; Lokiec, F; Poindessous, V; Raymond, E; Serova, M; Waters, SJ1
Bullerman, LB; Cetin, Y1
Casero, RA; Davidson, NE; Hacker, A; Huang, Y; Pledgie, A; Woster, PM; Zhang, Z1
Aninat, C; Fardel, O; Le Vee, M; Sparfel, L; Van Grevenynghe, J1
Emi, M; Kim, R; Tanabe, K; Toge, T; Uchida, Y1
Cabot, PJ; Davis, B; Monteith, GR; Roberts-Thomson, SJ; Robinson, JA; Venkata, NG1
Agama, K; Antony, S; Brantley, E; Kohlhagen, G; Meng, L; Pommier, Y; Sausville, EA; Stinson, SF1
Cho, KH; Kang, JH; Lee, YY; Roh, YK; Yang, BS; Yoon, DK; Yu, BY1
Al-Makdissy, N; Becuwe, P; Chedotal, A; Collet, P; Dauça, M; Devignes, MD; Domenjoud, L; Donner, M; Huin-Schohn, C; Kerjan, G; Murad, H; Schohn, H1
Karasek, M; Kunert-Radek, J; Lawnicka, H; Pawlikowski, M; Winczyk, K1
Livaniou, E; Papadopoulos, M; Paravatou-Petsotas, M; Patsis, G; Pelecanou, M; Pirmettis, IC; Tzanopoulou, S1
Gao, M; Lacy, G; Miller, KD; Sledge, GW; Wang, M; Zheng, QH1
Duncan, R; Gee, J; Gee, S; Greco, F; Jones, AT; Nicholson, RI; Vicent, MJ1
Dering, J; Finn, RS; Ginther, C; Glaspy, P; Slamon, DJ; Tchekmedyian, N; Wilson, CA1
Clark, E; Fairchild, C; Han, X; Huang, F; Lee, F; Platero, S; Reeves, K; Shaw, P; Wong, TW1
Chodyński, M; Fitak, H; Kutner, A; Opolski, A; Wietrzyk, J; Wojdat, E1
Altundag, K; Bulut, N; Dede, DS; Dizdar, O1
Jarois, T; Ju, D; Xie, Y; Xu, H1
Chan, AS; Cheng, CH; Cheng, GY; Cheung, F; Chui, CH; Gambari, R; Kok, SH; Lai, PB; Lam, WS; Lau, FY; Tang, JC; Teo, IT; Wong, RS; Yu, MW1
Bianco, S; Chalbos, D; Kersual, N; Lanvin, O; Vanacker, JM1
Altundag, K; Dizdar, O; Harputluoglu, H1
Aung, CS; Cabot, PJ; Monteith, GR; Roberts-Thomson, SJ; Venkata, NG1
Chang, YC; Fujiwara, I; Furukawa, C; Magae, J; Mizuta, M; Mizuta, N; Nakajima, H; Sakaguchi, K1
Bae, I; Eling, TE; Kang, BD; Kang, HJ; Kim, HJ; Kwon, SH; Lee, SH1
Al-Saadi, MS; Faidallah, HM; Rostom, SA1
Hisatsugu, T; Katano, M; Kubota, E; Matsuo, T; Nagumo, F; Tadano, J1
Houlbrook, S; Moody, CJ; Stephens, MA; Stratford, IJ; Swann, E1
Katano, M; Matsunaga, H; Mori, M; Nagumo, F; Saita, T1
Alton, P; Elgie, A; Hill, JG; Sargent, J; Taylor, CG; Wilson, J1
Alexander, P; Davies, DE; Lelieveld, P; McCall, CJ; Richter, A; Stevens, MF1
Fumi, G; Grignani, F; Migliorati, G; Nicoletti, I; Pagliacci, MC; Riccardi, C; Smacchia, M; Spinozzi, F1
Eliason, JF; Kaufmann, F; Tanaka, T; Tsukaguchi, T1
Bradshaw, TD; Fichtner, I; Lelieveld, P; McCall, CJ; Shi, DF; Stevens, MF; Wrigley, S1
Asanuma, F; Hoshiya, Y; Kitajima, M; Koh, JI; Kubota, T; Matsuzaki, SW; Watanabe, M; Yamada, Y1
Copaceanu, ML; Cottin, E; Coucke, PA; Li, YX; Mirimanoff, RO; Ozsahin, M; Paschoud, N1
Aggarwal, BB; McQueen, T; Mehta, K; Pantazis, P1
Moody, CJ; Roffey, JR; Stephens, MA; Stratford, IJ1
Day, BW; Falck, JR; Gerwick, WH; Hamel, E; Lai, JY; Marquez, B; Nagle, DG; Nambu, M; Verdier-Pinard, P; White, JD; Yoo, HD; Yu, J1
Bradshaw, TD; Paull, KD; Schultz, RJ; Shi, DF; Stevens, MF; Wrigley, S1
Asou, H; Elstner, E; Heber, D; Koeffler, HP; Koshizuka, K; Müller, C; Park, D; Said, JW; Shintaku, P; Williamson, EA1
Batist, G; Chen, X1
Huang, Y; Jiang, ZF; Li, YB; Liu, XQ; Song, ST; Tang, ZM; Xu, JM; Zhou, L1
Balog, A; Bertino, JR; Chou, TC; Danishefsky, SJ; Harris, CR; Kuduk, SD; Savin, KA; Zhang, XG1
Grant, MH; Rodgers, EH1
Grisé, KR; Laird, EC; McFadden, DW; Rongione, AJ1
Jiang, ZF; Liu, XQ; Liu, XW; Song, ST; Tang, ZM; Xu, JM; Zhang, J; Zhou, L1
Balduini, CL; Belletti, S; Da Prada, GA; Noris, P; Spedini, P; Zambelli, A1
Hamaguchi, Y; Hasegawa, S; Hisatomi, H; Ichikawa, Y; Ishikawa, T; Kamiyama, M; Momiyama, N; Narita, T; Shimada, H1
Drebin, JA; Greene, MI; Montone, KT; Murali, R; Peavey, JE; Wang, Q; Zhang, H1
Kniss, DA; Li, HM; Liu, L; Sabourin, CL; Seewaldt, V; Smith, PJ; Yee, LD1
Bowen, S; Gill, ZP; Holly, JM; Newcomb, PV; Perks, CM1
Song, S; Tang, Z; Xu, J1
Bradshaw, TD; Diana, P; Seaton, A; Shi, DF; Stevens, MF; Wells, G; Westwell, AD1
Kalus, AM; Rubin, GL; Simpson, ER; Zhao, Y1
Iffert, T; Maser, E; Moeller, A; Soldan, M1
Heisler, T; McFadden, DW; Simon, N; Towfigh, S1
Houlbrook, S; Lockyer, S; Moody, CJ; Roffey, JR; Strafford, IJ; Swann, E1
Bradshaw, TD; Brantley, E; Chua, MS; Kashiyama, E; Sausville, EA; Stevens, MF; Stinson, SF1
Devriendt, D; Journe, F; Kinnaert, E; Leclercq, G; Ma, Y; Seo, HS; Van Houtte, P1
Chen, P; Day, BW; Grant, SG; Kozusko, F; Panetta, JC1
Bradshaw, TD; Chua, MS; Shi, DF; Stevens, MF; Westwell, AD1
Borzilleri, R; Fairchild, CR; Kim, SH; Kramer, RA; Lee, FY; Long, BH; Reventos-Suarez, C; Rose, WC; Vite, GD1
Jiang, ZF; Liu, XQ; Liu, XW; Paradiso, A; Song, ST; Tang, ZM; Xu, JM; Zhang, J1
Atsumi, G; Chilton, FH; Clay, CE; Fonteh, AN; High, KP; Namen, AM; Trimboli, AJ1
Collins, AR; Hsueh, WA; Kim, S; Law, RE; Liu, Z; Van Herle, AJ; Wakino, S; Yin, F1
Leder, P; Martin, SS1
Albert, PS; Ferrari, N; Fine, HA; Hampl, M; Lee, J; Tanaka, T1
Fan, S; Gao, M; Goldberg, ID; Kitsis, RN; Laterra, J; Rosen, EM1
Fu, LW; Lin, GY; Pan, QC1
Bradshaw, TD; Hose, C; Loaiza-Pérez, AI; Sausville, EA; Singh, SS; Stevens, MF; Trapani, V; Trepel, JB1
Chopin, V; Jouy, N; Le Bourhis, X; Toillon, RA1
Bhalla, KN; Huang, Z; Lee, MW; Paranawithana, SR; Wang, HG; Yamaguchi, H1
Goto, K; Mu, YM; Nawata, H; Nishi, Y; Nomura, M; Okabe, T; Takayanagi, R; Yanase, T1
Barhoumi, R; Burghardt, RC; Kochevar, DT; Mealey, KL; Safe, S1
Bruwiere, H; Dillen, L; Floren, W; Janicot, M; Janssen, B; Moelans, P; Sanz, G; van der Leede, BJ; van Dun, J; Van Ginckel, R; Van Heusden, J; Van Hove, C; Venet, M; Willemsens, G; Wouters, W1
Dai, J; Dong, C; Hill, SM; Kiefer, TL; Lai, L; Ram, PT; Yuan, L1
Djiane, J; Gourdou, I; Laud, K; Pessemesse, L; Peyrat, JP1
Bruggisser, R; Jundt, G; Schaffner, W; Tullberg-Reinert, H; von Daeniken, K1
Azzi, S; Guillemin, F; Lignon, D; Merlin, JL; Ramacci, C; Zeghari, N1
Hisatsugu, T; Katano, M; Matsunaga, H; Morita, H; Oogushi, K; Sunaga, T; Yamamoto, H1
Fujita, F; Fujita, M; Inaba, H; Kusuyama, T; Sakamoto, Y; Shimozuma, K; Taguchi, T; Tanigawa, K1
Meisels, A; Schieweck, K; Schmidt-Ruppin, KH; Schott, E; Storni, A1

Reviews

13 review(s) available for thiazoles and Breast Neoplasms

ArticleYear
Recent Trends in Drug Development for the Treatment of Adenocarcinoma Breast Cancer: Thiazole, Triazole, and Thiosemicarbazone Analogues as Efficient Scaffolds.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Drug Development; Female; Humans; Thiazoles; Thiosemicarbazones; Triazoles

2022
A multidisciplinary approach to optimizing care of patients treated with alpelisib.
    Breast (Edinburgh, Scotland), 2022, Volume: 61

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Phosphatidylinositol 3-Kinases; Thiazoles

2022
Pharmacokinetics and Pharmacodynamic of Alpelisib.
    Clinical pharmacokinetics, 2023, Volume: 62, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fulvestrant; Humans; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Thiazoles

2023
Synergistic therapeutic potential of alpelisib in cancers (excluding breast cancer): Preclinical and clinical evidences.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 159

    Topics: Antineoplastic Agents; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Neoplasms; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Thiazoles

2023
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

2016
Alpelisib to treat breast cancer.
    Drugs of today (Barcelona, Spain : 1998), 2020, Volume: 56, Issue:6

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Clinical Trials as Topic; Fulvestrant; Humans; Mutation; Receptor, ErbB-2; Thiazoles

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses

2021
Alpelisib in the treatment of metastatic HR+ breast cancer with
    Future oncology (London, England), 2021, Volume: 17, Issue:1

    Topics: Breast Neoplasms; Chemotherapy, Adjuvant; Class I Phosphatidylinositol 3-Kinases; Clinical Trials as Topic; Drug Resistance, Neoplasm; Female; Humans; Mutation; Neoadjuvant Therapy; Progression-Free Survival; Protein Kinase Inhibitors; Receptors, Estrogen; Receptors, Progesterone; Thiazoles

2021
Which Is the Most Appropriate PI3K Inhibitor for Breast Cancer Patients with or without PIK3CA Status Mutant? A Systematic Review and Network Meta-Analysis.
    BioMed research international, 2020, Volume: 2020

    Topics: Aminopyridines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Clinical Trials as Topic; Female; Humans; Morpholines; Mutation; Network Meta-Analysis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Progression-Free Survival; Signal Transduction; Thiazoles; Treatment Outcome

2020
Observations with alpelisib in older patients (≥ 65 year of age) with breast cancer in a non-clinical trial setting.
    Breast cancer research and treatment, 2021, Volume: 188, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Mutation; Thiazoles

2021
Alpelisib: First Global Approval.
    Drugs, 2019, Volume: 79, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Drug Approval; Female; Fulvestrant; Humans; Male; Mutation; Protein Kinase Inhibitors; Receptor, ErbB-2; Thiazoles; United States; United States Food and Drug Administration

2019
Cathepsin K inhibitors as treatment of bone metastasis.
    Current opinion in supportive and palliative care, 2008, Volume: 2, Issue:3

    Topics: Azepines; Benzamides; Biphenyl Compounds; Bone Neoplasms; Bone Remodeling; Bone Resorption; Breast Neoplasms; Cathepsin K; Cathepsins; Female; Humans; Male; Osteoclasts; Piperazines; Prostatic Neoplasms; Sulfones; Thiazoles

2008
Predicting tumour response to anti-HER1 therapy using medical imaging: a literature review and in vitro study of [18F]-FDG incorporation by breast cancer cells responding to cetuximab.
    British journal of biomedical science, 2011, Volume: 68, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cetuximab; Colony-Forming Units Assay; ErbB Receptors; Female; Fluorodeoxyglucose F18; Glucose; Hexokinase; Humans; Lactic Acid; Positron-Emission Tomography; Tetrazolium Salts; Thiazoles

2011

Trials

26 trial(s) available for thiazoles and Breast Neoplasms

ArticleYear
A phase III trial of alpelisib + trastuzumab ± fulvestrant versus trastuzumab + chemotherapy in HER2+
    Future oncology (London, England), 2022, Volume: 18, Issue:19

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Clinical Trials, Phase III as Topic; Female; Fulvestrant; Humans; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles; Trastuzumab

2022
Alpelisib Monotherapy for PI3K-Altered, Pretreated Advanced Breast Cancer: A Phase II Study.
    Cancer discovery, 2022, 09-02, Volume: 12, Issue:9

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Mutation; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Thiazoles; Triple Negative Breast Neoplasms

2022
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

2016
Time course and management of key adverse events during the randomized phase III SOLAR-1 study of PI3K inhibitor alpelisib plus fulvestrant in patients with HR-positive advanced breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2020, Volume: 31, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fulvestrant; Humans; Male; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses

2021
FDA Approval Summary: Alpelisib Plus Fulvestrant for Patients with HR-positive, HER2-negative, PIK3CA-mutated, Advanced or Metastatic Breast Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 04-01, Volume: 27, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Double-Blind Method; Drug Approval; Female; Fulvestrant; Humans; Male; Middle Aged; Mutation; Neoplasm Metastasis; Patient Reported Outcome Measures; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles

2021
Alpelisib plus fulvestrant for PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: final overall survival results from SOLAR-1.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2021, Volume: 32, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Male; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles

2021
Alpelisib Plus Letrozole Shows Promise After CDK 4/6 Inhibitor Therapy in PIK3CA-Mutated HR+/HER2- Advanced Breast Cancer.
    The oncologist, 2021, Volume: 26 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Female; Humans; Letrozole; Receptor, ErbB-2; Thiazoles

2021
Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative study.
    The Lancet. Oncology, 2021, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aged; Aromatase Inhibitors; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Middle Aged; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Thiazoles

2021
Effectiveness of Alpelisib + Fulvestrant Compared with Real-World Standard Treatment Among Patients with HR+, HER2-, PIK3CA-Mutated Breast Cancer.
    The oncologist, 2021, Volume: 26, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles

2021
A Phase I Study of Alpelisib in Combination with Trastuzumab and LJM716 in Patients with
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 07-15, Volume: 27, Issue:14

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Middle Aged; Mutation; Neoplasm Metastasis; Receptor, ErbB-2; Thiazoles; Trastuzumab

2021
Potential for Long-Term Disease Control with Alpelisib Plus Fulvestrant Spans Patient Subgroups in HR+ PIK3CA-Mutated Advanced Breast Cancer.
    The oncologist, 2021, Volume: 26 Suppl 3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Receptor, ErbB-2; Thiazoles

2021
Phosphatidylinositol 3-Kinase α-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018, 05-01, Volume: 36, Issue:13

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Middle Aged; Thiazoles; Treatment Outcome

2018
Phase I study of alpelisib (BYL-719) and trastuzumab emtansine (T-DM1) in HER2-positive metastatic breast cancer (MBC) after trastuzumab and taxane therapy.
    Breast cancer research and treatment, 2018, Volume: 171, Issue:2

    Topics: Ado-Trastuzumab Emtansine; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Bridged-Ring Compounds; Female; Humans; Kaplan-Meier Estimate; Maximum Tolerated Dose; Maytansine; Middle Aged; Neoplasm Staging; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Retreatment; Taxoids; Thiazoles; Trastuzumab; Treatment Outcome

2018
Alpelisib Plus Fulvestrant in PIK3CA-Altered and PIK3CA-Wild-Type Estrogen Receptor-Positive Advanced Breast Cancer: A Phase 1b Clinical Trial.
    JAMA oncology, 2019, 02-01, Volume: 5, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Disease Progression; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Maximum Tolerated Dose; Middle Aged; Mutation; Progression-Free Survival; Protein Kinase Inhibitors; Receptors, Estrogen; Thiazoles; Time Factors

2019
Alpelisib for
    The New England journal of medicine, 2019, 05-16, Volume: 380, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Diarrhea; Female; Fulvestrant; Humans; Male; Middle Aged; Mutation; Progression-Free Survival; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Thiazoles

2019
Dasatinib plus capecitabine for advanced breast cancer: safety and efficacy in phase I study CA180004.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Apr-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Capecitabine; Dasatinib; Deoxycytidine; Female; Fluorouracil; Humans; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pyrimidines; Thiazoles; Treatment Outcome

2013
Gene signature-guided dasatinib therapy in metastatic breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Oct-15, Volume: 20, Issue:20

    Topics: Adult; Aged; Antineoplastic Agents; Biopsy; Breast Neoplasms; Dasatinib; Female; Gene Expression Profiling; Humans; Middle Aged; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrimidines; Risk Factors; src-Family Kinases; Thiazoles; Transcriptome; Treatment Outcome

2014
LYN-activating mutations mediate antiestrogen resistance in estrogen receptor-positive breast cancer.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:12

    Topics: Amino Acid Substitution; Aminopyridines; Animals; Breast Neoplasms; Dasatinib; Drug Resistance, Neoplasm; Drug Synergism; Estrogen Receptor Modulators; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Morpholines; Mutation, Missense; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Receptors, Estrogen; src Homology Domains; src-Family Kinases; Thiazoles; Xenograft Model Antitumor Assays

2014
Preventive Analgesic Efficacy of Nefopam in Acute and Chronic Pain After Breast Cancer Surgery: A Prospective, Double-Blind, and Randomized Trial.
    Medicine, 2016, Volume: 95, Issue:20

    Topics: Acute Pain; Adult; Aged; Analgesics, Non-Narcotic; Axilla; Breast Neoplasms; Chemoradiotherapy, Adjuvant; Chronic Pain; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ketorolac; Mastectomy, Segmental; Meloxicam; Middle Aged; Nefopam; Pain Measurement; Pain, Postoperative; Preoperative Care; Prospective Studies; Sentinel Lymph Node Biopsy; Thiazines; Thiazoles

2016
A phase I study of dasatinib and weekly paclitaxel for metastatic breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Dasatinib; Edema; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Paclitaxel; Pleural Effusion, Malignant; Pyrimidines; Thiazoles; Treatment Outcome

2011
Phase II trial of dasatinib in patients with metastatic breast cancer using real-time pharmacodynamic tissue biomarkers of Src inhibition to escalate dosing.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Sep-15, Volume: 17, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Dasatinib; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Metastasis; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Thiazoles

2011
A phase 2 trial of dasatinib in patients with advanced HER2-positive and/or hormone receptor-positive breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Nov-01, Volume: 17, Issue:21

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Dasatinib; Female; Humans; Middle Aged; Protein Kinase Inhibitors; Pyrimidines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; src-Family Kinases; Thiazoles

2011
Efficacy of meloxicam in combination with preoperative chemotherapy for breast cancer - Japan Breast Cancer Research Network (JBCRN) 02-1 trial.
    Anticancer research, 2011, Volume: 31, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Combined Modality Therapy; Cyclooxygenase Inhibitors; Female; Humans; Japan; Logistic Models; Meloxicam; Middle Aged; Nervous System Diseases; Preoperative Care; Thiazines; Thiazoles; Treatment Outcome; Young Adult

2011
Incremental increase in VEGFR1⁺ hematopoietic progenitor cells and VEGFR2⁺ endothelial progenitor cells predicts relapse and lack of tumor response in breast cancer patients.
    Breast cancer research and treatment, 2012, Volume: 132, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Breast Neoplasms; Cell Count; Cohort Studies; Dasatinib; Female; Hemangioblasts; Hematopoietic Stem Cells; Humans; Lapatinib; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pyrimidines; Quinazolines; Thiazoles; Trastuzumab; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2012
Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: a phase II study.
    Breast cancer research and treatment, 2003, Volume: 79, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Chromans; Disease Progression; Female; Humans; Liver; Middle Aged; Neoplasm Invasiveness; Thiazoles; Thiazolidinediones; Treatment Outcome; Troglitazone

2003

Other Studies

324 other study(ies) available for thiazoles and Breast Neoplasms

ArticleYear
Camalexin, an indole phytoalexin, inhibits cell proliferation, migration, and mammosphere formation in breast cancer cells via the aryl hydrocarbon receptor.
    Journal of natural medicines, 2022, Volume: 76, Issue:1

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Indoles; Phytoalexins; Receptors, Aryl Hydrocarbon; Sesquiterpenes; Thiazoles

2022
Design and development of novel fasudil derivatives as potent antibreast cancer agent that improves intestinal flora and intestinal barrier function in rats.
    Chemical biology & drug design, 2021, Volume: 98, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Agents; Breast Neoplasms; Colon; Drug Screening Assays, Antitumor; Female; Gastrointestinal Microbiome; Humans; Lipid Peroxidation; Mammary Neoplasms, Experimental; MCF-7 Cells; Rats, Sprague-Dawley; rho-Associated Kinases; Thiazoles

2021
Sensitive and robust liquid biopsy-based detection of PIK3CA mutations in hormone-receptor-positive metastatic breast cancer patients.
    British journal of cancer, 2022, Volume: 126, Issue:3

    Topics: Breast Neoplasms; Circulating Tumor DNA; Class I Phosphatidylinositol 3-Kinases; Estrogen Receptor alpha; Female; High-Throughput Nucleotide Sequencing; Humans; Liquid Biopsy; Mutation; Neoplasm Metastasis; Receptors, Progesterone; Thiazoles

2022
Adverse events of alpelisib: A postmarketing study of the World Health Organization pharmacovigilance database.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Breast Neoplasms; Databases, Factual; Diarrhea; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; Humans; Hyperglycemia; Pharmacovigilance; Thiazoles; World Health Organization

2022
Factors leading to alpelisib discontinuation in patients with hormone receptor positive, human epidermal growth factor receptor-2 negative breast cancer.
    Breast cancer research and treatment, 2022, Volume: 192, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Middle Aged; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles; Triple Negative Breast Neoplasms

2022
Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2- Advanced Breast Cancer.
    The oncologist, 2022, 03-28, Volume: 27, Issue:Suppl 1

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Letrozole; Thiazoles

2022
Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Lung Neoplasms; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship; Thiazoles

2022
Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer.
    British journal of cancer, 2022, Volume: 127, Issue:5

    Topics: Androgen Receptor Antagonists; Androgens; Breast Neoplasms; Cell Line, Tumor; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Naphthalenes; Piperidines; Pyrrolidines; Radiation Tolerance; Receptors, Androgen; Receptors, Estrogen; Tamoxifen; Thiazoles; Triazoles

2022
A PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions.
    Molecular cancer, 2022, 07-22, Volume: 21, Issue:1

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Mutation; Organoids; Thiazoles

2022
Fatostatin inhibits SREBP2-mediated cholesterol uptake via LDLR against selective estrogen receptor α modulator-induced hepatic lipid accumulation.
    Chemico-biological interactions, 2022, Sep-25, Volume: 365

    Topics: Breast Neoplasms; Cholesterol; Estrogen Receptor alpha; Female; Humans; Liver; Non-alcoholic Fatty Liver Disease; Pyridines; Receptors, LDL; Selective Estrogen Receptor Modulators; Sterol Regulatory Element Binding Protein 2; Tamoxifen; Thiazoles

2022
Synthesis and Biological Evaluation of Thiazole-Based Derivatives with Potential against Breast Cancer and Antimicrobial Agents.
    International journal of molecular sciences, 2022, Aug-30, Volume: 23, Issue:17

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Microbial Sensitivity Tests; Spectroscopy, Fourier Transform Infrared; Thiazoles

2022
Alpelisib for PIK3CA-Mutated Advanced Breast Cancer.
    The New England journal of medicine, 2019, 08-15, Volume: 381, Issue:7

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Humans; Thiazoles

2019
Alpelisib for PIK3CA-Mutated Advanced Breast Cancer.
    The New England journal of medicine, 2019, 08-15, Volume: 381, Issue:7

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Humans; Thiazoles

2019
Alpelisib for PIK3CA-Mutated Advanced Breast Cancer. Reply.
    The New England journal of medicine, 2019, 08-15, Volume: 381, Issue:7

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Humans; Thiazoles

2019
Precision medicine: PI3K targeting in advanced breast cancer.
    Breast cancer research and treatment, 2019, Volume: 178, Issue:2

    Topics: Biomarkers, Tumor; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Molecular Targeted Therapy; Mutation; Phosphoinositide-3 Kinase Inhibitors; Precision Medicine; PTEN Phosphohydrolase; Thiazoles

2019
New Drug for Breast Cancer with Specific Genetic Mutations.
    The American journal of nursing, 2019, Volume: 119, Issue:9

    Topics: Adult; Breast Neoplasms; Female; Humans; Middle Aged; Mutation; Thiazoles

2019
Double
    Science (New York, N.Y.), 2019, 11-08, Volume: 366, Issue:6466

    Topics: Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Class Ia Phosphatidylinositol 3-Kinase; Drug Resistance, Neoplasm; Female; Humans; Mutation; Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Protein Binding; Protein Domains; Thiazoles

2019
Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells.
    Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase Inhibitors; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Proteomics; Signal Transduction; Thiazoles

2020
Novel breast cancer treatment leads to hyperglycaemia.
    Diabetic medicine : a journal of the British Diabetic Association, 2020, Volume: 37, Issue:5

    Topics: Aged; Antineoplastic Agents, Hormonal; Blood Glucose; Blood Glucose Self-Monitoring; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Hyperglycemia; Monitoring, Ambulatory; Phosphoinositide-3 Kinase Inhibitors; Prediabetic State; Thiazoles

2020
Cannabidiolic acid dampens the expression of cyclooxygenase-2 in MDA-MB-231 breast cancer cells: Possible implication of the peroxisome proliferator-activated receptor β/δ abrogation.
    The Journal of toxicological sciences, 2020, Volume: 45, Issue:4

    Topics: Breast Neoplasms; Cannabinoids; Cyclooxygenase 2; Female; Gene Expression; Humans; PPAR delta; Signal Transduction; Sulfones; Thiazoles; Thiophenes; Transcription Factor AP-1; Tumor Cells, Cultured

2020
Frequency and spectrum of PIK3CA somatic mutations in breast cancer.
    Breast cancer research : BCR, 2020, 05-13, Volume: 22, Issue:1

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Cohort Studies; Databases, Genetic; Disease-Free Survival; Female; Genetic Testing; Humans; Molecular Targeted Therapy; Mutation; Predictive Value of Tests; Thiazoles

2020
The MyD88 inhibitor TJ-M2010-2 suppresses proliferation, migration and invasion of breast cancer cells by regulating MyD88/GSK-3β and MyD88/NF-κB signalling pathways.
    Experimental cell research, 2020, 09-15, Volume: 394, Issue:2

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cytokines; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Glycogen Synthase Kinase 3 beta; Humans; Lipopolysaccharides; Macrophages; Mice, Inbred BALB C; Mice, Nude; Myeloid Differentiation Factor 88; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; NF-kappa B; Piperazines; Signal Transduction; Thiazoles; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
Dermatologic adverse events related to the PI3Kα inhibitor alpelisib (BYL719) in patients with breast cancer.
    Breast cancer research and treatment, 2020, Volume: 183, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antineoplastic Agents; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Dose-Response Relationship, Drug; Drug Eruptions; Eosinophilia; Exanthema; Female; Histamine Antagonists; Humans; Middle Aged; Neoplasm Proteins; Protein Kinase Inhibitors; Randomized Controlled Trials as Topic; Retrospective Studies; Thiazoles

2020
A Phase Ib Study of Alpelisib or Buparlisib Combined with Tamoxifen Plus Goserelin in Premenopausal Women with HR-Positive HER2-Negative Advanced Breast Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 01-15, Volume: 27, Issue:2

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclin-Dependent Kinase 4; Female; Goserelin; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Tamoxifen; Thiazoles

2021
Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors.
    Bioorganic & medicinal chemistry, 2020, 09-15, Volume: 28, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Breast Neoplasms; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; MCF-7 Cells; Molecular Docking Simulation; Protein Kinase Inhibitors; Quantitative Structure-Activity Relationship; Thiazoles

2020
Combined LIM kinase 1 and p21-Activated kinase 4 inhibitor treatment exhibits potent preclinical antitumor efficacy in breast cancer.
    Cancer letters, 2020, 11-28, Volume: 493

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Lim Kinases; MAP Kinase Signaling System; Mice; p21-Activated Kinases; Phosphorylation; Pyrazoles; Pyrroles; Thiazoles; Xenograft Model Antitumor Assays

2020
Phase Ib Study of Ribociclib plus Fulvestrant and Ribociclib plus Fulvestrant plus PI3K Inhibitor (Alpelisib or Buparlisib) for HR
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 01-15, Volume: 27, Issue:2

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclin-Dependent Kinase 4; Female; Fulvestrant; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Purines; Receptors, Estrogen; Thiazoles

2021
Fatostatin in Combination with Tamoxifen Induces Synergistic Inhibition in ER-Positive Breast Cancer.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Pyridines; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen; Thiazoles

2020
A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo.
    Neoplasia (New York, N.Y.), 2020, Volume: 22, Issue:10

    Topics: Androgen Receptor Antagonists; Animals; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Mice; Mice, SCID; Piperidines; Proteolysis; Pyrrolidines; Receptors, Androgen; Thiazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
[New European approvals: Alpelisib for HRpos/HER2neg metastatic breast cancer with PIK3CA mutation].
    Bulletin du cancer, 2020, Volume: 107, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Class I Phosphatidylinositol 3-Kinases; Clinical Trials as Topic; Drug Approval; Drug Resistance, Neoplasm; Estrogens; Female; Fulvestrant; Humans; Male; Multicenter Studies as Topic; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Progesterone; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Thiazoles

2020
Paper-supported co-culture system for dynamic investigations of the lung-tropic migration of breast cancer cells.
    Biomedical materials (Bristol, England), 2021, 02-25, Volume: 16, Issue:2

    Topics: Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cell Survival; Coculture Techniques; Disease Progression; Epithelial-Mesenchymal Transition; Female; Fibroblasts; Humans; Lung; Lung Neoplasms; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Paper; Signal Transduction; Stromal Cells; Tetrazolium Salts; Thiazoles; Tumor Microenvironment

2021
Setting the Pick: Can PI3K Inhibitors Circumvent CDK4/6 Inhibitor Resistance?
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 01-15, Volume: 27, Issue:2

    Topics: Aminopyridines; Breast Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Female; Goserelin; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Tamoxifen; Thiazoles

2021
Avatrombopag Optimizes Response to Niraparib by Managing Thrombocytopenia Associated with Poly-ADP Ribose Polymerase (PARP) Inhibition in Ovarian Cancer and Breast Cancer: A Case Series.
    The American journal of case reports, 2020, Nov-16, Volume: 21

    Topics: Adenosine Diphosphate Ribose; Breast Neoplasms; Female; Humans; Indazoles; Ovarian Neoplasms; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thiazoles; Thiophenes; Thrombocytopenia

2020
Combined the SMAC mimetic and BCL2 inhibitor sensitizes neoadjuvant chemotherapy by targeting necrosome complexes in tyrosine aminoacyl-tRNA synthase-positive breast cancer.
    Breast cancer research : BCR, 2020, 11-25, Volume: 22, Issue:1

    Topics: Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Biopsy; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Clinical Decision-Making; Drug Synergism; Female; Humans; Mastectomy; Mitochondrial Proteins; Necroptosis; Neoadjuvant Therapy; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Thiazoles; Tyrosine-tRNA Ligase

2020
SOLAR1s: alpelisib returns to earth?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2021, Volume: 32, Issue:2

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Fulvestrant; Humans; Thiazoles

2021
ESMO20 YO for YO: highlights on new drugs in advanced breast cancer focusing on sacituzumab govitecan and alpelisib.
    ESMO open, 2021, Volume: 6, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Camptothecin; Female; Humans; Immunoconjugates; Thiazoles

2021
Continuing Advancements in Breast Cancer Care.
    Oncology (Williston Park, N.Y.), 2021, Jan-11, Volume: 35, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Clinical Trials as Topic; Humans; Medical Oncology; Paclitaxel; Thiazoles

2021
Nobiletin promotes the pyroptosis of breast cancer via regulation of miR-200b/JAZF1 axis.
    The Kaohsiung journal of medical sciences, 2021, Volume: 37, Issue:7

    Topics: Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Co-Repressor Proteins; DNA-Binding Proteins; Female; Flavones; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs; NF-kappa B; Pyroptosis; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection

2021
Alpelisib-induced hyperglycemia in older patients with breast Cancer: Qualitative findings.
    Journal of geriatric oncology, 2021, Volume: 12, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Hyperglycemia; Thiazoles

2021
Induction of interferon-β and interferon signaling by TRAIL and Smac mimetics via caspase-8 in breast cancer cells.
    PloS one, 2021, Volume: 16, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspase 8; Cell Line, Tumor; Female; Humans; Interferon-beta; MCF-7 Cells; Mitochondrial Proteins; Signal Transduction; Thiazoles; TNF-Related Apoptosis-Inducing Ligand

2021
Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant.
    Breast cancer research : BCR, 2021, 05-21, Volume: 23, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Fulvestrant; Genomics; Humans; Mice; Middle Aged; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Prognosis; Proto-Oncogene Proteins pp60(c-src); Receptors, Estrogen; Signal Transduction; Thiazoles; Xenograft Model Antitumor Assays

2021
Inhibition of the PI3K/mTOR Pathway in Breast Cancer to Enhance Response to Immune Checkpoint Inhibitors in Breast Cancer.
    International journal of molecular sciences, 2021, May-14, Volume: 22, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Female; Granulocytes; Humans; Immune Checkpoint Inhibitors; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Morpholines; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Quinazolines; Thiazoles; TOR Serine-Threonine Kinases; Treatment Outcome; Triazines; Tumor Microenvironment; Xenograft Model Antitumor Assays

2021
Cell Line-Specific Network Models of ER
    Cancer research, 2021, 09-01, Volume: 81, Issue:17

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Computer Simulation; Cyclin-Dependent Kinase Inhibitor p27; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Fulvestrant; HEK293 Cells; Humans; MCF-7 Cells; Models, Theoretical; Myeloid Cell Leukemia Sequence 1 Protein; Receptors, Estrogen; Retinoblastoma Binding Proteins; Signal Transduction; Thiazoles; Ubiquitin-Protein Ligases

2021
Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors.
    Archiv der Pharmazie, 2021, Volume: 354, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Female; Humans; Imidazoles; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inhibitory Concentration 50; Kidney Neoplasms; MCF-7 Cells; Models, Molecular; Structure-Activity Relationship; Thiazoles

2021
ER+ Breast Cancer Strongly Depends on MCL-1 and BCL-xL Anti-Apoptotic Proteins.
    Cells, 2021, 07-02, Volume: 10, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Estrogen Receptor alpha; Everolimus; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Myeloid Cell Leukemia Sequence 1 Protein; Piperazines; Protein Isoforms; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; Signal Transduction; Sulfonamides; Thiazoles; Thiophenes

2021
A Phase I Study of LSZ102, an Oral Selective Estrogen Receptor Degrader, with or without Ribociclib or Alpelisib, in Patients with Estrogen Receptor-Positive Breast Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 11-01, Volume: 27, Issue:21

    Topics: Adult; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Purines; Receptors, Estrogen; Thiazoles; Thiophenes

2021
Integration of Receptor Tyrosine Kinases Determines Sensitivity to PI3Kα-selective Inhibitors in Breast Cancer.
    Theranostics, 2017, Volume: 7, Issue:4

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; Drug Resistance; Female; Gene Expression Profiling; Heterografts; Humans; Mice, SCID; Protein-Tyrosine Kinases; Thiazoles; Treatment Failure

2017
Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation.
    Oncotarget, 2017, Jun-13, Volume: 8, Issue:24

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Proliferation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 2-Ring; Humans; Mice; Mice, Transgenic; Neoplastic Stem Cells; Polycomb Repressive Complex 1; Thiazoles; Tumor Cells, Cultured

2017
Going beyond genetics to discover cancer targets.
    Genome biology, 2017, 05-22, Volume: 18, Issue:1

    Topics: Animals; Antineoplastic Agents; Atlases as Topic; Breast Neoplasms; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Mice; Molecular Targeted Therapy; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Receptor, ErbB-2; Thiazoles; Xenograft Model Antitumor Assays

2017
The reversion of anti-cancer drug antagonism of tamoxifen and docetaxel by the hyaluronic acid-decorated polymeric nanoparticles.
    Pharmacological research, 2017, Volume: 126

    Topics: A549 Cells; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coumarins; Docetaxel; Female; Humans; Hyaluronic Acid; Male; MCF-7 Cells; Mice; Nanoparticles; Polymers; Tamoxifen; Taxoids; Thiazoles

2017
Inhibition of the V-ATPase by Archazolid A: A New Strategy to Inhibit EMT.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:11

    Topics: Breast Neoplasms; Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Macrolides; Neoplasm Metastasis; Neoplastic Stem Cells; Thiazoles; Vacuolar Proton-Translocating ATPases

2017
Modulation of telomere protection by the PI3K/AKT pathway.
    Nature communications, 2017, 11-02, Volume: 8, Issue:1

    Topics: Aging; Animals; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; DNA Damage; Humans; Mice; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Stability; Proto-Oncogene Proteins c-akt; Telomere; Telomeric Repeat Binding Protein 1; Thiazoles

2017
Analgesics promote welfare and sustain tumour growth in orthotopic 4T1 and B16 mouse cancer models.
    Laboratory animals, 2018, Volume: 52, Issue:4

    Topics: Analgesics; Animal Welfare; Animals; Breast Neoplasms; Buprenorphine; Cell Line, Tumor; Disease Models, Animal; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma, Experimental; Meloxicam; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Metastasis; Pain; Thiazines; Thiazoles; Xenograft Model Antitumor Assays

2018
Synthesis and cytotoxicity evaluation of thiazole derivatives obtained from 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene- 3-carbonitrile.
    Acta pharmaceutica (Zagreb, Croatia), 2017, Dec-20, Volume: 67, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytotoxins; Hep G2 Cells; Humans; Liver Neoplasms; Nasopharyngeal Neoplasms; Stomach Neoplasms; Thiazoles

2017
Albumin-covered lipid nanocapsules exhibit enhanced uptake performance by breast-tumor cells.
    Colloids and surfaces. B, Biointerfaces, 2018, May-01, Volume: 165

    Topics: Breast Neoplasms; Cell Proliferation; Cell Survival; Coumarins; Curcumin; Drug Liberation; Endocytosis; Female; Humans; Lipids; MCF-7 Cells; Nanocapsules; Serum Albumin; Thiazoles

2018
Inhibition of TACC3 by a small molecule inhibitor in breast cancer.
    Biochemical and biophysical research communications, 2018, 04-15, Volume: 498, Issue:4

    Topics: Apoptosis; Aurora Kinase A; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Microtubule-Associated Proteins; Neoplasm Proteins; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proteomics; Proto-Oncogene Proteins; Signal Transduction; Thiazoles

2018
Development of Thiazole-5-carboxylate Derivatives as Selective Inhibitors of Monoacylglycerol Lipase as Target in Cancer.
    Mini reviews in medicinal chemistry, 2019, Volume: 19, Issue:5

    Topics: Antineoplastic Agents; Arachidonic Acids; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Endocannabinoids; Enzyme Inhibitors; Female; Glycerides; Humans; Lung Neoplasms; Molecular Docking Simulation; Monoacylglycerol Lipases; Neoplasms; Structure-Activity Relationship; Thiazoles

2019
Enhancing the Cancer Cell Growth Inhibitory Effects of Table Grape Anthocyanins.
    Journal of food science, 2018, Volume: 83, Issue:9

    Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caco-2 Cells; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Female; Fruit; Glucosides; HT29 Cells; Humans; Methylation; Nitriles; Oxidative Stress; Phytotherapy; Plant Extracts; Tetrazolium Salts; Thiazoles; Vitis

2018
Unexpected Benefit from Alpelisib and Fulvestrant in a Woman with Highly Pre-treated ER-Positive, HER2-Negative PIK3CA Mutant Metastatic Breast Cancer.
    Clinical drug investigation, 2018, Volume: 38, Issue:11

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Middle Aged; Mutation; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles

2018
Ligand-activated interaction of PPARδ with c-Myc governs the tumorigenicity of breast cancer.
    International journal of cancer, 2018, 12-01, Volume: 143, Issue:11

    Topics: A549 Cells; Animals; Breast Neoplasms; Carcinogenesis; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; HEK293 Cells; HeLa Cells; Humans; Ligands; MCF-7 Cells; PC12 Cells; PPAR delta; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Rats; RNA, Small Interfering; Thiazoles

2018
Inhibition of BTF3 sensitizes luminal breast cancer cells to PI3Kα inhibition through the transcriptional regulation of ERα.
    Cancer letters, 2019, Volume: 440-441

    Topics: Animals; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Estrogen Receptor alpha; Female; G2 Phase; Gene Knockdown Techniques; Humans; MCF-7 Cells; Mice; Mice, Nude; Nuclear Proteins; Thiazoles; Transcription Factors; Transcription, Genetic; Xenograft Model Antitumor Assays

2019
GPR119 agonist enhances gefitinib responsiveness through lactate-mediated inhibition of autophagy.
    Journal of experimental & clinical cancer research : CR, 2018, Nov-29, Volume: 37, Issue:1

    Topics: Animals; Autophagy; Breast Neoplasms; Cell Line, Tumor; Drug Synergism; Female; Gefitinib; Humans; Lactic Acid; MCF-7 Cells; Mesylates; Mice, Inbred BALB C; Mice, Nude; Oxadiazoles; Receptors, G-Protein-Coupled; Tetrazoles; Thiazoles; Transfection

2018
Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel small molecule LDC3/Dynarrestin.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; CSK Tyrosine-Protein Kinase; Drug Interactions; Enzyme Activation; Homeostasis; Humans; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Protein Interaction Maps; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Signal Transduction; Thiazoles

2019
Tumor microenvironmental growth factors induce long-term estrogen deprivation resistance in breast cancer.
    Breast cancer (Tokyo, Japan), 2019, Volume: 26, Issue:6

    Topics: Aromatase Inhibitors; Breast Neoplasms; Cell Survival; Drug Resistance, Neoplasm; Epidermal Growth Factor; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Receptor, ErbB-2; Thiazoles; Transfection; Tumor Microenvironment

2019
Alpelisib effective in advanced-stage disease.
    Nature reviews. Clinical oncology, 2019, Volume: 16, Issue:8

    Topics: Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Humans; Thiazoles

2019
Alpelisib plus fulvestrant for PIK3CA-mutated breast cancer.
    The Lancet. Oncology, 2019, Volume: 20, Issue:7

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Drug Combinations; Fulvestrant; Humans; Mutation; Thiazoles

2019
Induction of Necroptosis in Human Breast Cancer Drug-Resistant Cells by SMAC Analog LCL161 After Caspase Inhibition Requires RIP3.
    Die Pharmazie, 2019, 06-01, Volume: 74, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Gene Knockdown Techniques; Humans; MCF-7 Cells; Mitochondria; Necroptosis; Receptor-Interacting Protein Serine-Threonine Kinases; RNA, Small Interfering; Thiazoles

2019
Trastuzumab-conjugated vitamin E TPGS liposomes for sustained and targeted delivery of docetaxel.
    Expert opinion on drug delivery, 2013, Volume: 10, Issue:6

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Area Under Curve; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coumarins; Docetaxel; Drug Carriers; Half-Life; Humans; Liposomes; Male; Microscopy, Confocal; Particle Size; Polyethylene Glycols; Rats, Sprague-Dawley; Receptor, ErbB-2; Spectroscopy, Fourier Transform Infrared; Taxoids; Thiazoles; Trastuzumab; Vitamin E

2013
Unraveling the mechanisms behind the enhanced MTT conversion by irradiated breast cancer cells.
    Radiation research, 2013, Volume: 179, Issue:4

    Topics: Breast Neoplasms; Cadherins; Cell Communication; Cell Count; Cell Line, Tumor; Female; Humans; Nitroblue Tetrazolium; Permeability; Tetrazolium Salts; Thiazoles

2013
Cytotoxic effect of ethanol extract of microalga, Chaetoceros calcitrans, and its mechanisms in inducing apoptosis in human breast cancer cell line.
    BioMed research international, 2013, Volume: 2013

    Topics: Annexin A5; Apoptosis; Biological Products; Breast Neoplasms; Cell Cycle; Cell Proliferation; Ethanol; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; MCF-7 Cells; Microalgae; Propidium; Regression Analysis; Tamoxifen; Tetrazolium Salts; Thiazoles

2013
Dasatinib : a novel therapy for breast cancer?
    Expert opinion on investigational drugs, 2013, Volume: 22, Issue:6

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Movement; Clinical Trials as Topic; Dasatinib; Drug Evaluation, Preclinical; ErbB Receptors; Female; Humans; Protein Kinase Inhibitors; Pyrimidines; Signal Transduction; src-Family Kinases; Thiazoles

2013
Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases.
    Journal of medicinal chemistry, 2013, May-23, Volume: 56, Issue:10

    Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Coloring Agents; Computer Simulation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; High-Throughput Screening Assays; Humans; Indicators and Reagents; Male; Models, Molecular; Phosphorylation; Structure-Activity Relationship; Testicular Neoplasms; Tetrazolium Salts; Thiazoles

2013
Dasatinib inhibits mammary tumour development in a genetically engineered mouse model.
    The Journal of pathology, 2013, Volume: 230, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents; beta Catenin; Breast Neoplasms; Cadherins; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dasatinib; Dose-Response Relationship, Drug; Drug Administration Schedule; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Integrases; Lactoglobulins; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neoplasm Invasiveness; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Pyrimidines; Signal Transduction; src-Family Kinases; Thiazoles; Time Factors

2013
The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells.
    The Journal of biological chemistry, 2013, Jun-28, Volume: 288, Issue:26

    Topics: Active Transport, Cell Nucleus; Amino Acid Motifs; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Female; Humans; Microscopy, Confocal; Phosphorylation; Proto-Oncogene Proteins c-fos; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles; Trans-Activators; Viral Regulatory and Accessory Proteins

2013
Docetaxel-loaded nanoparticles based on star-shaped mannitol-core PLGA-TPGS diblock copolymer for breast cancer therapy.
    Acta biomaterialia, 2013, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, Gel; Coumarins; Docetaxel; Female; Humans; Inhibitory Concentration 50; Lactic Acid; Magnetic Resonance Spectroscopy; Mannitol; MCF-7 Cells; Molecular Weight; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Taxoids; Thermogravimetry; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays

2013
A c-Myc activation sensor-based high-throughput drug screening identifies an antineoplastic effect of nitazoxanide.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:9

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Heterografts; High-Throughput Screening Assays; Humans; Mice; Mice, Nude; Molecular Imaging; Neoplasm Transplantation; Nitro Compounds; Proto-Oncogene Proteins c-myc; Thiazoles

2013
CHL1 is involved in human breast tumorigenesis and progression.
    Biochemical and biophysical research communications, 2013, Aug-23, Volume: 438, Issue:2

    Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Transplantation; RNA, Small Interfering; Tetrazolium Salts; Thiazoles

2013
Folic acid conjugated δ-valerolactone-poly(ethylene glycol) based triblock copolymer as a promising carrier for targeted doxorubicin delivery.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Annexin A5; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Screening Assays, Antitumor; Esters; Female; Folic Acid; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Micelles; Polyethylene Glycols; Pyrones; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles

2013
Magnolol induces apoptosis in MCF-7 human breast cancer cells through G2/M phase arrest and caspase-independent pathway.
    Die Pharmazie, 2013, Volume: 68, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Biphenyl Compounds; Bisbenzimidazole; Breast Neoplasms; Caspases; Cell Division; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cytochromes c; Female; Flow Cytometry; G2 Phase; Genes, bcl-2; Humans; Indicators and Reagents; Lignans; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles

2013
Borrelidin has limited anti-cancer effects in bcl-2 overexpressing breast cancer and leukemia cells and reveals toxicity in non-malignant breast epithelial cells.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:10

    Topics: Adenosine Triphosphate; Antibiotics, Antineoplastic; Blotting, Western; Breast; Breast Neoplasms; Cell Line, Tumor; Epithelial Cells; Fatty Alcohols; Female; Genes, bcl-2; Human Umbilical Vein Endothelial Cells; Humans; Leukemia; Tetrazolium Salts; Thiazoles

2014
A rationally designed photo-chemo core-shell nanomedicine for inhibiting the migration of metastatic breast cancer cells followed by photodynamic killing.
    Nanomedicine : nanotechnology, biology, and medicine, 2014, Volume: 10, Issue:3

    Topics: Breast; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Dasatinib; Drug Carriers; Female; Humans; Lactic Acid; Mesoporphyrins; Molecular Docking Simulation; Nanomedicine; Neoplasm Metastasis; Photochemotherapy; Photosensitizing Agents; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein-Tyrosine Kinases; Pyrimidines; Serum Albumin; Thiazoles

2014
A novel liposomal nanomedicine for nitric oxide delivery and breast cancer treatment.
    Bio-medical materials and engineering, 2014, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Lipids; Liposomes; Mannitol; Nanoparticles; Nitric Oxide; Pressure; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors

2014
Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:2

    Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Disease-Free Survival; Endothelial Cells; Erythropoietin; Female; Gene Expression Regulation; Humans; Hypoxia; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplastic Stem Cells; Recurrence; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors

2014
Evaluating the potential bioactivity of a novel compound ER1626.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Movement; Cell Proliferation; Chick Embryo; Endometrial Neoplasms; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Indenes; Isoquinolines; Ketones; MCF-7 Cells; Molecular Structure; Quinolones; Receptors, Estrogen; Tetrazolium Salts; Thiazoles

2014
V-ATPase inhibition regulates anoikis resistance and metastasis of cancer cells.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:4

    Topics: Animals; Anoikis; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms, Experimental; Macrolides; Male; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Signal Transduction; Thiazoles; Urinary Bladder Neoplasms

2014
Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor
    Cellular signalling, 2014, Volume: 26, Issue:5

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; CSK Tyrosine-Protein Kinase; Female; Fingolimod Hydrochloride; Humans; Lysophospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Estrogen; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; src-Family Kinases; Thiazoles; Tyrosine

2014
Dasatinib-letrozole gets split verdict.
    Cancer discovery, 2014, Volume: 4, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Dasatinib; Female; Humans; Letrozole; Nitriles; Protein Kinase Inhibitors; Pyrimidines; Receptor, ErbB-2; Receptors, Estrogen; Thiazoles; Treatment Outcome; Triazoles

2014
Down-regulation of nicotinamide N-methyltransferase induces apoptosis in human breast cancer cells via the mitochondria-mediated pathway.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cytochromes c; DNA Primers; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Mice; Mitochondria; Nicotinamide N-Methyltransferase; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles

2014
Label-free fluorescent biosensor based on the target recycling and Thioflavin T-induced quadruplex formation for short DNA species of c-erbB-2 detection.
    Analytica chimica acta, 2014, Mar-19, Volume: 817

    Topics: Base Pair Mismatch; Benzothiazoles; Biosensing Techniques; Breast Neoplasms; DNA; Female; Fluorescent Dyes; G-Quadruplexes; Humans; Nucleic Acid Amplification Techniques; Receptor, ErbB-2; Saliva; Thiazoles

2014
Metabotropic glutamate receptor-1 as a novel target for the antiangiogenic treatment of breast cancer.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Benzimidazoles; Breast Neoplasms; Cell Line; Cell Proliferation; Endothelial Cells; Female; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Naphthalenes; Receptors, Metabotropic Glutamate; Thiazoles

2014
Activity of a novel Hec1-targeted anticancer compound against breast cancer cell lines in vitro and in vivo.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cytoskeletal Proteins; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 4 or More Rings; Humans; In Vitro Techniques; MCF-7 Cells; Mice; Molecular Targeted Therapy; Niacinamide; Nuclear Proteins; Thiazoles; Xenograft Model Antitumor Assays

2014
Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:21

    Topics: Breast Neoplasms; Cell Nucleus; Cell Proliferation; Cell Survival; Female; Fluorescent Dyes; Hot Temperature; Humans; Hyperthermia, Induced; MCF-7 Cells; Metal Nanoparticles; Microscopy, Confocal; Nanotechnology; Ribosomes; Tetrazolium Salts; Thiazoles

2014
Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles.
    European journal of medicinal chemistry, 2014, May-22, Volume: 79

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Death; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Molecular Structure; Pyrroles; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured

2014
Synthesis of silver nanoparticles from Melia dubia leaf extract and their in vitro anticancer activity.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Sep-15, Volume: 130

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Female; Green Chemistry Technology; Humans; MCF-7 Cells; Melia; Metal Nanoparticles; Microscopy, Electron, Scanning; Plant Extracts; Plant Leaves; Silver; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Vero Cells; X-Ray Diffraction

2014
The cyclin-dependent kinase inhibitor SNS-032 induces apoptosis in breast cancer cells via depletion of Mcl-1 and X-linked inhibitor of apoptosis protein and displays antitumor activity in vivo.
    International journal of oncology, 2014, Volume: 45, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase 2; Female; Heterografts; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Oxazoles; Real-Time Polymerase Chain Reaction; Thiazoles; X-Linked Inhibitor of Apoptosis Protein

2014
Perfluorooctanoic acid stimulates breast cancer cells invasion and up-regulates matrix metalloproteinase-2/-9 expression mediated by activating NF-κB.
    Toxicology letters, 2014, Aug-17, Volume: 229, Issue:1

    Topics: Blotting, Western; Breast Neoplasms; Caprylates; Cell Line, Tumor; Coloring Agents; Female; Fluorocarbons; Humans; Indicators and Reagents; Luciferases; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Real-Time Polymerase Chain Reaction; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Up-Regulation

2014
Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer.
    Oncotarget, 2014, Oct-15, Volume: 5, Issue:19

    Topics: Acinar Cells; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dasatinib; Drug Synergism; Estradiol; Estrogens; Female; Fulvestrant; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Receptor, IGF Type 1; Receptors, Estrogen; Signal Transduction; Thiazoles; Xenograft Model Antitumor Assays

2014
Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression.
    Cancer research, 2014, Sep-01, Volume: 74, Issue:17

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Dasatinib; Drug Resistance, Neoplasm; Female; Genes, src; Humans; MCF-7 Cells; Mice; Phosphorylation; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-akt; Pyrimidines; Rats; Signal Transduction; Sirolimus; Thiazoles; TOR Serine-Threonine Kinases

2014
Detection of increased 64Cu uptake by human copper transporter 1 gene overexpression using PET with 64CuCl2 in human breast cancer xenograft model.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014, Volume: 55, Issue:10

    Topics: Animals; Breast Neoplasms; Cation Transport Proteins; Cell Line, Tumor; Cisplatin; Copper; Copper Radioisotopes; Copper Transporter 1; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Kinetics; Mice; Positron-Emission Tomography; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays

2014
4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasis.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Animals; Breast Neoplasms; Cell Proliferation; Female; Humans; Hydrazones; Mice; Neoplasm Metastasis; Neoplastic Stem Cells; Signal Transduction; Thiazoles

2014
Cytotoxic constituents from the rhizomes of Curcuma zedoaria.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Analysis of Variance; Breast Neoplasms; Cell Proliferation; Chromatography, Thin Layer; Curcuma; Female; Human Umbilical Vein Endothelial Cells; Humans; Indonesia; Malaysia; MCF-7 Cells; Microscopy, Fluorescence; Molecular Structure; Phytotherapy; Plant Extracts; Rhizome; Tetrazolium Salts; Thiazoles

2014
Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway.
    Breast cancer research : BCR, 2014, Sep-25, Volume: 16, Issue:5

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Claudins; Epithelial-Mesenchymal Transition; Female; Gene Expression; Heterocyclic Compounds, 2-Ring; Humans; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Receptor Cross-Talk; RNA, Messenger; Signal Transduction; Thiazoles; Transcription Factors; Zinc Finger Protein GLI1

2014
Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.
    Nature, 2015, Feb-12, Volume: 518, Issue:7538

    Topics: Alleles; Animals; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Drug Resistance, Neoplasm; Female; Humans; Loss of Heterozygosity; Mice; Mice, Nude; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Thiazoles; Xenograft Model Antitumor Assays

2015
Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Dec-16, Volume: 111, Issue:50

    Topics: Animals; Blotting, Western; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Diphosphonates; Drug Repositioning; ErbB Receptors; Female; Flow Cytometry; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Molecular Dynamics Simulation; Protein Binding; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay

2014
Dasatinib reverses the multidrug resistance of breast cancer MCF-7 cells to doxorubicin by downregulating P-gp expression via inhibiting the activation of ERK signaling pathway.
    Cancer biology & therapy, 2015, Volume: 16, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Dasatinib; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; MCF-7 Cells; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; RNA, Messenger; Thiazoles

2015
Measurement of PIP3 levels reveals an unexpected role for p110β in early adaptive responses to p110α-specific inhibitors in luminal breast cancer.
    Cancer cell, 2015, Jan-12, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice; Mice, Nude; Neoplasm Transplantation; ortho-Aminobenzoates; Pyrimidinones; Receptor, ErbB-2; Signal Transduction; Thiazoles

2015
Breaking up is hard to do: PI3K isoforms on the rebound.
    Cancer cell, 2015, Jan-12, Volume: 27, Issue:1

    Topics: Aniline Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromones; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Neoplasms; ortho-Aminobenzoates; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Pyrimidinones; Thiazoles

2015
The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206.
    Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Heterocyclic Compounds, 3-Ring; Humans; Hydrazones; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred BALB C; Mice, Nude; Multiprotein Complexes; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases; Transplantation, Heterologous

2015
Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells.
    Chemical research in toxicology, 2015, May-18, Volume: 28, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Female; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; MCF-7 Cells; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Thiazoles

2015
Potential antiproliferative effect of isoxazolo- and thiazolo coumarin derivatives on breast cancer mediated bone and lung metastases.
    Acta pharmaceutica (Zagreb, Croatia), 2015, Volume: 65, Issue:1

    Topics: 4-Hydroxycoumarins; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Isoxazoles; Lung Neoplasms; Thiazoles; Time Factors

2015
Kalkitoxin inhibits angiogenesis, disrupts cellular hypoxic signaling, and blocks mitochondrial electron transport in tumor cells.
    Marine drugs, 2015, Mar-20, Volume: 13, Issue:3

    Topics: Angiogenesis Inhibitors; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Electron Transport Complex I; Female; Humans; Hypoxia-Inducible Factor 1; Inhibitory Concentration 50; Lipids; Mitochondria; Neovascularization, Pathologic; Signal Transduction; Thiazoles; Vascular Endothelial Growth Factor A

2015
The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro.
    Molecular pharmacology, 2015, Volume: 87, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Benzamides; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA Repair; Female; Heterografts; Humans; Mice, Inbred NOD; Mutagenicity Tests; Neoplasm Transplantation; Ribonucleotide Reductases; Thiazoles; Zebrafish

2015
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer.
    Science translational medicine, 2015, Apr-15, Volume: 7, Issue:283

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Endoplasmic Reticulum; Estrogen Receptor alpha; Female; Humans; MCF-7 Cells; Mice; Mice, Nude; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Research Design; Signal Transduction; Thiazoles

2015
Exercise-induced changes in tumour LDH-B and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice.
    The Journal of physiology, 2015, Jun-15, Volume: 593, Issue:12

    Topics: Animals; Basigin; Breast Neoplasms; Cell Line, Tumor; ERRalpha Estrogen-Related Receptor; Female; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Mice, Inbred BALB C; Monocarboxylic Acid Transporters; Muscle Proteins; Nitriles; Physical Conditioning, Animal; Receptors, Estrogen; Symporters; Thiazoles; Tumor Burden

2015
Synergistic antitumor activity of vitamin D3 combined with metformin in human breast carcinoma MDA-MB-231 cells involves m-TOR related signaling pathways.
    Die Pharmazie, 2015, Volume: 70, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Drug Synergism; Female; Humans; Hypoglycemic Agents; Metformin; Signal Transduction; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Vitamins

2015
Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer.
    Cancer research, 2015, Jul-15, Volume: 75, Issue:14

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Iron; Macrolides; MCF-7 Cells; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Thiazoles; Tumor Cells, Cultured; Vacuolar Proton-Translocating ATPases; Xenograft Model Antitumor Assays

2015
Marketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant Therapy.
    Molecular pharmacology, 2015, Volume: 88, Issue:3

    Topics: Adjuvants, Pharmaceutic; Anastrozole; Anilides; Animals; Antifungal Agents; Antineoplastic Agents; Breast Neoplasms; Cholestanetriol 26-Monooxygenase; Dexmedetomidine; Enzyme Inhibitors; Fadrozole; Female; Hypnotics and Sedatives; Mice; Mice, Inbred C57BL; Nitriles; Protein Binding; Thiazoles; Tosyl Compounds; Triazoles

2015
Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells.
    Oncotarget, 2015, Jun-20, Volume: 6, Issue:17

    Topics: Acetylcarnitine; Breast Neoplasms; Cell Adhesion; Cell Proliferation; Cell Survival; Chromatography, Liquid; Doxycycline; ERRalpha Estrogen-Related Receptor; Forkhead Box Protein M1; Forkhead Transcription Factors; Glycolysis; Humans; MCF-7 Cells; Mitochondria; Neoplastic Stem Cells; Nitriles; Oligomycins; Organelle Biogenesis; Oxidative Phosphorylation; Proteomics; Receptors, Estrogen; Signal Transduction; Spheroids, Cellular; Tandem Mass Spectrometry; Thiazoles; Wnt Signaling Pathway

2015
PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers.
    Oncogene, 2016, 07-07, Volume: 35, Issue:27

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Drug Resistance, Neoplasm; Female; Humans; Lapatinib; Mammary Neoplasms, Experimental; Mice, Knockout; Molecular Targeted Therapy; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines; Receptor, ErbB-2; Signal Transduction; Thiazoles; Tumor Burden; Xenograft Model Antitumor Assays

2016
Smac mimetic‑induced caspase‑independent necroptosis requires RIP1 in breast cancer.
    Molecular medicine reports, 2016, Volume: 13, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Breast Neoplasms; Caspase Inhibitors; Caspases; Cell Proliferation; Female; Humans; Inhibitor of Apoptosis Proteins; MCF-7 Cells; Membrane Potential, Mitochondrial; Necrosis; Nuclear Pore Complex Proteins; Proteolysis; RNA-Binding Proteins; Thiazoles

2016
Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells.
    Oncotarget, 2016, Jan-12, Volume: 7, Issue:2

    Topics: Animals; Antimalarials; Antineoplastic Agents, Hormonal; Apoptosis; Autophagy; Benzamides; Blotting, Western; Breast Neoplasms; Cell Proliferation; Chloroquine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred NOD; Mice, SCID; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleoside Diphosphate Reductase; RNA, Messenger; Tamoxifen; Thiazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition.
    Breast cancer research : BCR, 2016, Apr-05, Volume: 18, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Class Ia Phosphatidylinositol 3-Kinase; Drug Resistance, Neoplasm; Female; Humans; Insulin Receptor Substrate Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Somatomedin; Thiazoles; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2016
Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.
    Bioorganic & medicinal chemistry, 2016, 07-01, Volume: 24, Issue:13

    Topics: Antineoplastic Agents; Benzenesulfonamides; Breast Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Proliferation; Cell Survival; Drug Delivery Systems; Female; Humans; Inhibitory Concentration 50; MCF-7 Cells; Molecular Structure; Sulfonamides; Thiazoles

2016
Novel quinolines carrying pyridine, thienopyridine, isoquinoline, thiazolidine, thiazole and thiophene moieties as potential anticancer agents.
    Acta pharmaceutica (Zagreb, Croatia), 2016, Jun-01, Volume: 66, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Inhibitory Concentration 50; Isoquinolines; MCF-7 Cells; Models, Molecular; Molecular Structure; Pyridines; Quinolines; Structure-Activity Relationship; Thiazoles; Thiazolidines; Thiophenes

2016
Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer.
    Cancer discovery, 2016, Volume: 6, Issue:10

    Topics: Breast Neoplasms; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Thiazoles; Up-Regulation

2016
Addition of the p110α inhibitor BYL719 overcomes targeted therapy resistance in cells from Her2-positive-PTEN-loss breast cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:11

    Topics: Aminopyridines; Animals; Antibodies; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Humans; Lapatinib; Mice; Morpholines; ortho-Aminobenzoates; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; PTEN Phosphohydrolase; Pyrimidinones; Quinazolines; Receptor, ErbB-2; Thiazoles; Xenograft Model Antitumor Assays

2016
Enhanced Bioactivity of α-Tocopheryl Succinate Based Block Copolymer Nanoparticles by Reduced Hydrophobicity.
    Macromolecular bioscience, 2016, Volume: 16, Issue:12

    Topics: alpha-Tocopherol; Antioxidants; Biocompatible Materials; Breast Neoplasms; Coumarins; Drug Delivery Systems; Female; Humans; Hydrophobic and Hydrophilic Interactions; Methacrylates; Nanoparticles; Polyethylene Glycols; Polymerization; Polymers; Thiazoles; Tumor Cells, Cultured

2016
GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment.
    Nature communications, 2016, 12-16, Volume: 7

    Topics: Animals; Benzamides; Bone Morphogenetic Protein Receptors; Breast Neoplasms; Cell Line, Tumor; Diamines; Dioxoles; Female; Gene Expression Regulation, Neoplastic; Glycosylation; Guanine Nucleotide Exchange Factors; Humans; Lung; Lung Neoplasms; Mice; Mice, Nude; Mutation; N-Acetylgalactosaminyltransferases; Neoplasms, Experimental; Polypeptide N-acetylgalactosaminyltransferase; Pyrazoles; Quinolines; Receptors, Notch; Receptors, Transforming Growth Factor beta; Thiazoles

2016
α-Tocopherol as functional excipient for resveratrol and coenzyme Q10-loaded SNEDDS for improved bioavailability and prophylaxis of breast cancer.
    Journal of drug targeting, 2017, Volume: 25, Issue:6

    Topics: Administration, Oral; alpha-Tocopherol; Animals; Antioxidants; Area Under Curve; Biological Availability; Breast Neoplasms; Caco-2 Cells; Coumarins; Drug Delivery Systems; Emulsions; Excipients; Female; Humans; Nanoparticles; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Thiazoles; Ubiquinone

2017
Acivicin with glutaminase regulates proliferation and invasion of human MCF-7 and OAW-42 cells--an in vitro study.
    Indian journal of experimental biology, 2008, Volume: 46, Issue:1

    Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Collagen; Drug Combinations; Female; Glutaminase; Glutamine; Humans; In Vitro Techniques; Isoxazoles; Laminin; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Ovarian Neoplasms; Proteoglycans; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A

2008
Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein).
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Nov-15, Volume: 35, Issue:4

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzofurans; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cell Survival; Crystallography, X-Ray; DNA, Complementary; Dogs; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluoresceins; Humans; Indicators and Reagents; Mitoxantrone; Models, Molecular; Neoplasm Proteins; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2008
Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer.
    Oncogene, 2008, Nov-27, Volume: 27, Issue:56

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glucuronidase; Humans; Insulin; Insulin-Like Growth Factor I; Ki-67 Antigen; Klotho Proteins; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Tissue Array Analysis

2008
The Na+/K+-ATPase is the Achilles heel of multi-drug-resistant cancer cells.
    Cancer letters, 2009, Sep-08, Volume: 282, Issue:1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cardenolides; Cell Line, Tumor; Cell Survival; Drug Resistance, Multiple; HeLa Cells; Humans; Hydroxyurea; Ligands; Neoplasms; Sodium-Potassium-Exchanging ATPase; Thiazoles

2009
Cellular toxicity of nanogenomedicine in MCF-7 cell line: MTT assay.
    Journal of visualized experiments : JoVE, 2009, Apr-03, Issue:26

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Coloring Agents; Humans; Nanostructures; Spectrophotometry; Tetrazolium Salts; Thiazoles; Toxicity Tests

2009
Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA Damage; Female; Gene Expression; Genes, bcl-2; Genes, p53; Humans; NF-kappa B; Phaeophyceae; Phloroglucinol; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Signal Transduction; Tetrazolium Salts; Thiazoles

2009
MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Benzamides; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Melanoma; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Tetrazolium Salts; Thiazoles

2009
Water extract of Rheum officinale Baill. induces apoptosis in human lung adenocarcinoma A549 and human breast cancer MCF-7 cell lines.
    Journal of ethnopharmacology, 2009, Jul-15, Volume: 124, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Lung Neoplasms; Phytotherapy; Rheum; Tetrazolium Salts; Thiazoles

2009
Src inhibitor dasatinib inhibits growth of breast cancer cells by modulating EGFR signaling.
    Cancer letters, 2009, Oct-08, Volume: 283, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dasatinib; ErbB Receptors; Female; Humans; Protein Kinase Inhibitors; Pyrimidines; Signal Transduction; src-Family Kinases; Thiazoles

2009
Synthesis and antitumoral activity of novel thiazolobenzotriazole, thiazoloindolo[3,2-c]quinoline and quinolinoquinoline derivatives.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:10

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type I; Female; Humans; Indoles; Leukemia; Quinolines; Thiazoles; Topoisomerase I Inhibitors; Triazoles

2009
Improvement in docetaxel-induced nail changes associated with cyclooxygenase-2 inhibitor treatment.
    Clinical and experimental dermatology, 2009, Volume: 34, Issue:7

    Topics: Antineoplastic Agents; Breast Neoplasms; Cyclooxygenase 2 Inhibitors; Docetaxel; Female; Humans; Meloxicam; Middle Aged; Nail Diseases; Taxoids; Thiazines; Thiazoles

2009
Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells.
    British journal of cancer, 2009, Jul-07, Volume: 101, Issue:1

    Topics: Actins; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Cytoskeleton; Dasatinib; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; G1 Phase; Humans; Neoplasm Invasiveness; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Thiazoles; Tubulin

2009
Cytotoxicity and estrogenicity of Invisalign appliances.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2009, Volume: 136, Issue:1

    Topics: Adenocarcinoma; Benzhydryl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Coloring Agents; Dental Materials; Endocrine Disruptors; Estradiol; Estrogens, Non-Steroidal; Female; Fibroblasts; Gingiva; Humans; Materials Testing; Orthodontic Appliance Design; Phenols; Receptors, Estrogen; Sodium Chloride; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Movement Techniques

2009
Hybrid pharmacophore design and synthesis of isatin-benzothiazole analogs for their anti-breast cancer activity.
    Bioorganic & medicinal chemistry, 2009, Nov-01, Volume: 17, Issue:21

    Topics: Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Indoles; Isatin; Thiazoles

2009
SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: Adenosine Diphosphate Ribose; Animals; Anthraquinones; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Breast Neoplasms; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Female; Humans; In Situ Nick-End Labeling; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Nude; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles

2010
LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer.
    Cancer research, 2010, Mar-15, Volume: 70, Issue:6

    Topics: Breast Neoplasms; Cell Line, Tumor; Dasatinib; Epithelial Cells; Female; Gene Expression Profiling; Humans; Mesoderm; Prognosis; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Thiazoles

2010
Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells.
    International journal of oncology, 2010, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Docetaxel; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors

2010
Thiazole antibiotics against breast cancer.
    Cell cycle (Georgetown, Tex.), 2010, Mar-15, Volume: 9, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Mice; Peptides; Thiazoles; Thiostrepton; Xenograft Model Antitumor Assays

2010
Development of candidate genomic markers to select breast cancer patients for dasatinib therapy.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:5

    Topics: Antineoplastic Agents; Biomarkers, Pharmacological; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Dasatinib; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Genome, Human; Humans; Matched-Pair Analysis; Oligonucleotide Array Sequence Analysis; Patient Selection; Prognosis; Pyrimidines; Thiazoles

2010
miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1.
    Breast cancer research and treatment, 2011, Volume: 126, Issue:3

    Topics: beta Catenin; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; High Mobility Group Proteins; Humans; MicroRNAs; Neoplasm Invasiveness; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Wnt Proteins

2011
ErbB-inhibitory protein: a modified ectodomain of epidermal growth factor receptor synergizes with dasatinib to inhibit growth of breast cancer cells.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:6

    Topics: Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dasatinib; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors; Female; Humans; Immunohistochemistry; Mice; Mice, SCID; Protein Structure, Tertiary; Pyrimidines; Rats; Receptor, ErbB-2; Recombinant Fusion Proteins; Recombinant Proteins; Thiazoles; Xenograft Model Antitumor Assays

2010
Induction of cell growth arrest and apoptotic cell death in human breast cancer MCF-7 cells by the COX-1 inhibitor FR122047.
    Oncology reports, 2010, Volume: 24, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma in Situ; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Female; Humans; Isoxazoles; Piperazines; Sulfonamides; Thiazoles

2010
Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:4

    Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Chitosan; Coumarins; Drug Carriers; Female; Flow Cytometry; Fluorescence; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence; Surface Properties; Technology, Pharmaceutical; Thiazoles; Tissue Distribution

2010
Mo(II) complexes: a new family of cytotoxic agents?
    Journal of inorganic biochemistry, 2010, Volume: 104, Issue:11

    Topics: 1-Octanol; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Molybdenum; Neoplasms; Neuroblastoma; Nucleic Acid Conformation; Phenanthrolines; Tetrazolium Salts; Thiazoles; Water

2010
Chiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: novel antitumor DNA monoalkylating agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; DNA; Drug Screening Assays, Antitumor; Female; Humans; Melanoma; Pyrroles; Thiazoles

2010
Effect of multikinase inhibitors on caspase-independent cell death and DNA damage in HER2-overexpressing breast cancer cells.
    Journal of the National Cancer Institute, 2010, Sep-22, Volume: 102, Issue:18

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Caspases; Cell Line, Tumor; Dasatinib; DNA Damage; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Protein Kinase Inhibitors; Pyrimidines; Receptor, ErbB-2; Thiazoles; Trastuzumab; Up-Regulation

2010
The sphingosine kinase 1 inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells.
    The Journal of biological chemistry, 2010, Dec-10, Volume: 285, Issue:50

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Densitometry; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; Phosphotransferases (Alcohol Group Acceptor); Prostatic Neoplasms; Proteasome Endopeptidase Complex; Thiazoles; Ubiquitin

2010
Preferential antitumor effect of the Src inhibitor dasatinib associated with a decreased proportion of aldehyde dehydrogenase 1-positive cells in breast cancer cells of the basal B subtype.
    BMC cancer, 2010, Oct-20, Volume: 10

    Topics: Aldehyde Dehydrogenase; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Dasatinib; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; Humans; Inhibitory Concentration 50; Neoplastic Stem Cells; Pyrimidines; src-Family Kinases; Thiazoles

2010
Inhibition of the c-fms proto-oncogene autocrine loop and tumor phenotype in glucocorticoid stimulated human breast carcinoma cells.
    Breast cancer research and treatment, 2011, Volume: 129, Issue:2

    Topics: Autocrine Communication; Breast Neoplasms; Carcinoma; Cell Adhesion; Cell Line, Tumor; Cell Movement; Dexamethasone; Dose-Response Relationship, Drug; Female; Glucocorticoids; Humans; Macrophage Colony-Stimulating Factor; Neoplasm Invasiveness; Oligonucleotides, Antisense; Phenotype; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Mas; Receptor, Macrophage Colony-Stimulating Factor; RNA Interference; Thiazoles; Transfection

2011
Anti-breast cancer activity of some novel 1,2-dihydropyridine, thiophene and thiazole derivatives.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Dihydropyridines; Humans; Inhibitory Concentration 50; Structure-Activity Relationship; Thiazoles; Thiophenes

2011
Significance of ER-Src axis in hormonal therapy resistance.
    Breast cancer research and treatment, 2011, Volume: 130, Issue:2

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Co-Repressor Proteins; Dasatinib; Drug Resistance, Neoplasm; Drug Synergism; Estrogen Receptor alpha; Female; Gene Knockdown Techniques; Humans; Letrozole; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Pyrimidines; Receptor, ErbB-2; RNA Interference; src-Family Kinases; Tamoxifen; Thiazoles; Transcription Factors; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays

2011
Pharmacological inhibition of sphingosine kinase isoforms alters estrogen receptor signaling in human breast cancer.
    Journal of molecular endocrinology, 2011, Volume: 46, Issue:3

    Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Computer Simulation; Estrogen Receptor alpha; Humans; Isoenzymes; Mass Spectrometry; Phosphotransferases (Alcohol Group Acceptor); Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiazoles

2011
Src: a potential target for the treatment of triple-negative breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cisplatin; Cytoplasm; Dasatinib; Female; Humans; Middle Aged; Molecular Targeted Therapy; Protein Kinase Inhibitors; Pyrimidines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; src-Family Kinases; Thiazoles

2011
Changes in 2-fluoro-2-deoxy-D-glucose incorporation, hexokinase activity and lactate production by breast cancer cells responding to treatment with the anti-HER-2 antibody trastuzumab.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Fluorodeoxyglucose F18; Glucose; Hexokinase; Humans; Lactic Acid; Receptor, ErbB-2; Tetrazolium Salts; Thiazoles; Trastuzumab; Tumor Stem Cell Assay

2011
Synthesis and biological activities of 2-amino-thiazole-5-carboxylic acid phenylamide derivatives.
    Archiv der Pharmazie, 2011, Volume: 344, Issue:7

    Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Combinatorial Chemistry Techniques; Dasatinib; Female; HT29 Cells; Humans; Inhibitory Concentration 50; Leukemia; Pyrimidines; Structure-Activity Relationship; Thiazoles

2011
Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death.
    Cancer biology & therapy, 2011, Aug-01, Volume: 12, Issue:3

    Topics: Animals; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Benzimidazoles; Benzodioxoles; Breast Neoplasms; Cell Death; Cell Line, Transformed; Cell Transformation, Neoplastic; Checkpoint Kinase 1; Dasatinib; Female; Fibroblasts; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Protease Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Pyrimidines; Quinazolines; Radiation Tolerance; src-Family Kinases; Thiazoles

2011
Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Count; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorimetry; Culture Media, Serum-Free; Deoxyuridine; DNA; Drug Design; Estradiol; Estrogens; Fingolimod Hydrochloride; Fluorescent Dyes; Fulvestrant; Humans; Isopropyl Thiogalactoside; Membrane Potential, Mitochondrial; Mitochondria; Propylene Glycols; Reproducibility of Results; Sphingosine; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p14ARF

2011
Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells.
    Cell cycle (Georgetown, Tex.), 2011, Aug-01, Volume: 10, Issue:15

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; Breast Neoplasms; Cell Line; Coculture Techniques; Dasatinib; Drug Resistance, Neoplasm; Female; Fibroblasts; Glycolysis; Humans; Pyrimidines; Tamoxifen; Telomerase; Thiazoles

2011
Cellular imaging assay for early evaluation of an apoptosis inducer.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:10

    Topics: Annexin A5; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cytological Techniques; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Microscopy, Confocal; Phosphatidylserines; Staurosporine; Surface Plasmon Resonance; Tetrazolium Salts; Thiazoles

2011
CYP2S1 and CYP2W1 mediate 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW-610, NSC 721648) sensitivity in breast and colorectal cancer cells.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:10

    Topics: Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Colorectal Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Induction; Female; Humans; Male; Thiazoles

2011
Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Acetamides; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Humans; Inhibitory Concentration 50; Leukemia; Mice; Morpholines; NIH 3T3 Cells; Protein Kinase Inhibitors; Pyridines; src-Family Kinases; Structure-Activity Relationship; Thiazoles

2011
Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PTK6 inhibitors.
    Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19

    Topics: Adaptor Proteins, Signal Transducing; Animals; Aurora Kinases; Breast Neoplasms; Computer Simulation; Dasatinib; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Design; Drug Discovery; Drug Screening Assays, Antitumor; Female; Humans; Imidazoles; Inhibitory Concentration 50; Melanocytes; Mice; Molecular Targeted Therapy; Neoplasm Proteins; Oncogenes; Phenotype; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogenes; Pyrazines; Pyrimidines; RNA-Binding Proteins; Structure-Activity Relationship; Thiazoles

2011
Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions.
    Cell cycle (Georgetown, Tex.), 2011, Sep-01, Volume: 10, Issue:17

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Dasatinib; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Immunoprecipitation; Metformin; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyrimidines; Receptor, ErbB-2; Receptor, IGF Type 1; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases; Trastuzumab

2011
Anticancer and radio-sensitizing evaluation of some new thiazolopyrane and thiazolopyranopyrimidine derivatives bearing a sulfonamide moiety.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Gamma Rays; Humans; Pyrans; Pyrimidines; Radiation-Sensitizing Agents; Sulfonamides; Thiazoles

2011
1-oxoeudesm-11(13)-ene-12,8α-lactone-induced apoptosis via ROS generation and mitochondria activation in MCF-7 cells.
    Archives of pharmacal research, 2011, Volume: 34, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Fractionation; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Female; Hepatocytes; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species; Sesquiterpenes, Eudesmane; Tetrazolium Salts; Thiazoles

2011
Comparison of in vitro cytotoxicity, estrogenicity and anti-estrogenicity of triclosan, perfluorooctane sulfonate and perfluorooctanoic acid.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:4

    Topics: Alkanesulfonic Acids; Breast Neoplasms; Caprylates; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Environmental Pollutants; Estrogen Antagonists; Estrogens, Non-Steroidal; Female; Fluorocarbons; Humans; Tetrazolium Salts; Thiazoles; Triclosan

2013
Lack of angiogenesis in experimental brain metastases.
    Journal of neuropathology and experimental neurology, 2011, Volume: 70, Issue:11

    Topics: Angiopoietin-1; Animals; Brain Neoplasms; Breast Neoplasms; Bromodeoxyuridine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; DNA-Binding Proteins; Electron Microscope Tomography; Female; Glial Fibrillary Acidic Protein; Humans; Keratins; Lamins; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Quinolines; Receptor, Platelet-Derived Growth Factor beta; Thiazoles; Vascular Endothelial Growth Factor A

2011
Two new imidazolone-containing alkaloids and further metabolites from the ascomycete fungus Tricladium sp.
    Chemistry & biodiversity, 2011, Volume: 8, Issue:10

    Topics: Alkaloids; Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Ascomycota; Breast Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Female; HIV-1; Humans; Imidazoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Thiazoles; Tryptamines

2011
The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer.
    Cancer cell, 2011, Oct-18, Volume: 20, Issue:4

    Topics: Breast Neoplasms; Carrier Proteins; Cell Proliferation; ERRalpha Estrogen-Related Receptor; Female; Humans; Nitriles; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; RNA-Binding Proteins; Signal Transduction; Thiazoles

2011
Dasatinib as a single agent in triple-negative breast cancer: results of an open-label phase 2 study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Nov-01, Volume: 17, Issue:21

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Dasatinib; Female; Humans; Middle Aged; Protein Kinase Inhibitors; Pyrimidines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; src-Family Kinases; Thiazoles

2011
Synthesis of novel isatin-thiazoline and isatin-benzimidazole conjugates as anti-breast cancer agents.
    Archives of pharmacal research, 2011, Volume: 34, Issue:10

    Topics: Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Female; Humans; Indicators and Reagents; Isatin; MCF-7 Cells; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thiazoles

2011
Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines--lessons for design of combination targeted therapy.
    Cancer letters, 2012, Jul-01, Volume: 320, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Breast Neoplasms; Butadienes; Cell Line, Tumor; Chromones; Dasatinib; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epothilones; Female; Humans; Morpholines; Niacinamide; Nitriles; Paclitaxel; Phenylurea Compounds; Pyridines; Pyrimidines; Signal Transduction; Sirolimus; Sorafenib; Tamoxifen; Thiazoles

2012
Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate.
    Journal of bioenergetics and biomembranes, 2012, Volume: 44, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Butyrates; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Pyruvates; Tetrazolium Salts; Thiazoles

2012
Preparation of a cationic nanoemulsome for intratumoral drug delivery and its enhancing effect on cellular uptake in vitro.
    Journal of nanoscience and nanotechnology, 2011, Volume: 11, Issue:10

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cations; Caveolae; Cell Line, Tumor; Cells, Cultured; Cetrimonium; Cetrimonium Compounds; CHO Cells; Clathrin; Coumarins; Cricetinae; Drug Carriers; Drug Delivery Systems; Emulsions; Female; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Nanoparticles; Particle Size; Pinocytosis; Polymers; Solvents; Thiazoles

2011
Effects of the combination of RAD001 and docetaxel on breast cancer stem cells.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Everolimus; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Nude; Sirolimus; Stem Cells; Taxoids; Tetrazolium Salts; Thiazoles

2012
Dual inhibition of sphingosine kinase isoforms ablates TNF-induced drug resistance.
    Oncology reports, 2012, Volume: 27, Issue:6

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; NF-kappa B; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Thiazoles; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2012
Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells.
    Cellular signalling, 2012, Volume: 24, Issue:6

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dasatinib; Female; Humans; Indoles; Neoplasm Invasiveness; Paxillin; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Sulfonamides; Thiazoles

2012
Uptake rate of cationic mitochondrial inhibitor MKT-077 determines cellular oxygen consumption change in carcinoma cells.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Kinetics; Mammary Neoplasms, Animal; Mathematical Concepts; Mitochondria; Oxygen Consumption; Pyridines; Rats; Thiazoles

2012
Phosphosignature predicts dasatinib response in non-small cell lung cancer.
    Molecular & cellular proteomics : MCP, 2012, Volume: 11, Issue:9

    Topics: Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Dasatinib; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Integrin beta4; Lung Neoplasms; Mass Spectrometry; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proteome; Pyrimidines; Thiazoles

2012
Forced mitotic entry of S-phase cells as a therapeutic strategy induced by inhibition of WEE1.
    Cancer discovery, 2012, Volume: 2, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Checkpoint Kinase 1; Cyclins; Deoxycytidine; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, SCID; Mitosis; Nuclear Proteins; Polycomb Repressive Complex 2; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Pyrimidinones; Quinolines; S Phase; Thiazoles; Thiophenes; Transcription Factors; Tumor Burden; Tumor Suppressor Protein p53; Urea; Xenograft Model Antitumor Assays

2012
CIL-102 binds to tubulin at colchicine binding site and triggers apoptosis in MCF-7 cells by inducing monopolar and multinucleated cells.
    Biochemical pharmacology, 2012, Sep-01, Volume: 84, Issue:5

    Topics: Apoptosis; Binding Sites; Breast Neoplasms; Calorimetry; Cell Line, Tumor; Cell Proliferation; Humans; Kinetics; Spectrometry, Fluorescence; Tetrazolium Salts; Thermodynamics; Thiazoles; Tubulin

2012
Peptidomimetic Src/pretubulin inhibitor KX-01 alone and in combination with paclitaxel suppresses growth, metastasis in human ER/PR/HER2-negative tumor xenografts.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:9

    Topics: Acetamides; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dasatinib; Drug Synergism; Estrogen Receptor alpha; Female; Focal Adhesion Kinase 1; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Morpholines; Neoplasm Invasiveness; Neoplasm Micrometastasis; Neovascularization, Pathologic; Paclitaxel; Peptidomimetics; Pyridines; Pyrimidines; Receptor, ErbB-2; Receptors, Progesterone; src-Family Kinases; Thiazoles; Tubulin Modulators; Tumor Burden; Xenograft Model Antitumor Assays

2012
RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.
    Cancer research, 2012, Oct-01, Volume: 72, Issue:19

    Topics: Animals; Antineoplastic Agents; Binding Sites; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Crystallography, X-Ray; Cytoskeleton; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Models, Molecular; Molecular Structure; Neoplasm Invasiveness; NIH 3T3 Cells; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; rho-Associated Kinases; Substrate Specificity; Thiazoles; Tumor Burden; Urea

2012
Lab reports and cat scans: can veterinary oncology guide our way to new treatments for human cancers?
    Future medicinal chemistry, 2012, Volume: 4, Issue:11

    Topics: Animals; Antineoplastic Agents; Benzamides; Breast Neoplasms; Cats; Disease Models, Animal; Dogs; Female; Humans; Imatinib Mesylate; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mast-Cell Sarcoma; Neoplasms; Piperazines; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Thiazoles; Transcriptome

2012
Sphingosine kinase isoforms as a therapeutic target in endocrine therapy resistant luminal and basal-A breast cancer.
    Experimental biology and medicine (Maywood, N.J.), 2012, Volume: 237, Issue:7

    Topics: Adamantane; Aminophenols; Animals; Antineoplastic Agents, Hormonal; Base Sequence; Breast Neoplasms; Cell Line, Tumor; DNA Primers; Drug Resistance, Neoplasm; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Isoenzymes; Mice; Mice, Nude; Mice, SCID; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Thiazoles; Xenograft Model Antitumor Assays

2012
Tumor suppression by small molecule inhibitors of translation initiation.
    Oncotarget, 2012, Volume: 3, Issue:8

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Eukaryotic Initiation Factor-2; Eukaryotic Initiation Factor-4F; Female; Humans; Hydrazones; Indoles; Male; Melanoma; Mice; Mice, Nude; Nitro Compounds; Peptide Chain Initiation, Translational; Phosphorylation; Protein Biosynthesis; RNA, Messenger; Thiazoles; Xenograft Model Antitumor Assays

2012
The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.
    Cancer research, 2012, Nov-15, Volume: 72, Issue:22

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Polarity; Down-Regulation; ErbB Receptors; Female; Humans; Macrolides; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; rab5 GTP-Binding Proteins; rac1 GTP-Binding Protein; Thiazoles; Vacuolar Proton-Translocating ATPases; Xenograft Model Antitumor Assays

2012
Novel SN38 conjugate-forming nanoparticles as anticancer prodrug: in vitro and in vivo studies.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Mar-10, Volume: 166, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Micelles; Nanoparticles; Prodrugs; Solubility; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays

2013
Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties.
    European journal of medicinal chemistry, 2013, Volume: 60

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Models, Molecular; Molecular Structure; Pyrroles; Structure-Activity Relationship; Thiazoles

2013
Reversal of multidrug resistance-associated protein-mediated daunorubicin resistance by camptothecin.
    Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:8

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line; Cell Nucleus; Chemokines, CC; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Microscopy, Confocal; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2002
A new cytotoxic epothilone from modified polyketide synthases heterologously expressed in Myxococcus xanthus.
    Journal of natural products, 2002, Volume: 65, Issue:7

    Topics: Antineoplastic Agents; Base Sequence; Binding Sites; Breast Neoplasms; Drug Screening Assays, Antitumor; Epothilones; Epoxy Compounds; Female; Genetic Engineering; Glioma; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Lung Neoplasms; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Multienzyme Complexes; Myxococcus xanthus; Nuclear Magnetic Resonance, Biomolecular; Thiazoles; Tubulin; Tumor Cells, Cultured

2002
Which dosing scheme is suitable for the taxanes? An in vitro model.
    Archives of pharmacal research, 2002, Volume: 25, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Division; Cell Survival; Docetaxel; Female; Humans; Indicators and Reagents; Paclitaxel; Taxoids; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2002
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity.
    British journal of cancer, 2002, Sep-09, Volume: 87, Issue:6

    Topics: Acridines; Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Cell Division; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Isoquinolines; Membrane Glycoproteins; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Ovarian Neoplasms; Tetrahydroisoquinolines; Tetraspanin 29; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2002
Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole.
    Molecular pharmacology, 2003, Volume: 63, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Female; Gene Expression; Gene Expression Profiling; Humans; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Tumor Cells, Cultured

2003
Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells.
    Cancer research, 2003, Mar-01, Volume: 63, Issue:5

    Topics: Breast Neoplasms; Cell Division; Cyclin D1; Cysteine Endopeptidases; Down-Regulation; Estrogen Receptor alpha; G1 Phase; Humans; Multienzyme Complexes; Prostaglandin D2; Proteasome Endopeptidase Complex; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; RNA, Messenger; S Phase; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Ubiquitin

2003
Effects of introduction of dThdPase cDNA on sensitivity to 5'-deoxy-5-fluorouridine and tumor angiogenesis.
    International journal of oncology, 2003, Volume: 22, Issue:4

    Topics: Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Floxuridine; Genetic Vectors; Humans; Immunohistochemistry; Inhibitory Concentration 50; Neoplasm Transplantation; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Time Factors; Transfection

2003
Oxidative stress and bioindicators of reproductive function in pulp and paper mill effluent exposed white sucker.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 74, Issue:1

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Breast Neoplasms; Cell Line; Dexamethasone; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Female; Glucocorticoids; Humans; Insecticides; Linuron; Luciferases; Oxidative Stress; Plasmids; Promoter Regions, Genetic; Receptors, Glucocorticoid; Sunscreening Agents; Testosterone Congeners; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Ultraviolet Rays

2003
Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.
    Oncogene, 2003, Jun-19, Volume: 22, Issue:25

    Topics: Adenocarcinoma; Antigens, Differentiation; Antigens, Neoplasm; Breast Neoplasms; Caveolin 1; Caveolin 2; Caveolins; Cell Differentiation; Cell Line; Chromans; Colonic Neoplasms; Dimerization; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Kidney; Ligands; Macromolecular Substances; Membrane Microdomains; Neoplasm Proteins; Phenotype; Phenylacetates; Prostaglandin D2; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; RNA, Neoplasm; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone; Tumor Cells, Cultured

2003
Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells.
    Cancer research, 2003, Jul-01, Volume: 63, Issue:13

    Topics: Apoptosis; Benzoates; Breast Neoplasms; Cell Division; Female; Gene Expression Regulation, Neoplastic; Humans; Ligands; Lung Neoplasms; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoids; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured

2003
A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Caspases; Cell Death; Cell Division; Cell Line, Tumor; Cell Nucleus; Cell Survival; Chromatin; Cytochromes c; Cytoplasm; Cytosol; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Models, Chemical; Neoplasm Transplantation; Nucleosomes; Poly(ADP-ribose) Polymerases; Polyamines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation

2003
Inactivation of NF-kappaB by genistein is mediated via Akt signaling pathway in breast cancer cells.
    Oncogene, 2003, Jul-24, Volume: 22, Issue:30

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Densitometry; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Genes, Reporter; Genistein; Humans; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured

2003
The pesticide malathion induces alterations in actin cytoskeleton and in cell adhesion of cultured breast carcinoma cells.
    International journal of oncology, 2003, Volume: 23, Issue:3

    Topics: Actins; beta Catenin; Blotting, Western; Breast Neoplasms; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cholinesterase Inhibitors; Coloring Agents; Cytoskeletal Proteins; Cytoskeleton; Electrophoresis; Humans; Insecticides; Malathion; Microscopy, Fluorescence; rac1 GTP-Binding Protein; rho GTP-Binding Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators

2003
Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.
    Molecular and cellular biology, 2003, Volume: 23, Issue:17

    Topics: 3T3 Cells; Animals; Breast; Breast Neoplasms; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Cyclin D1; Ecdysterone; Epithelial Cells; Fatty Liver; Female; Gene Expression Regulation; Humans; Mice; Mice, Mutant Strains; Mice, Transgenic; Models, Molecular; Mutation; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Reference Values; Repressor Proteins; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation

2003
Antitumor benzothiazoles. Frontier molecular orbital analysis predicts bioactivation of 2-(4-aminophenyl)benzothiazoles to reactive intermediates by cytochrome P4501A1.
    Organic & biomolecular chemistry, 2003, Feb-07, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Benzothiazoles; Binding Sites; Biotransformation; Breast Neoplasms; Cations; Cell Death; Cytochrome P-450 CYP1A1; DNA Adducts; Dose-Response Relationship, Drug; Female; Humans; Hydrocarbons, Fluorinated; Models, Molecular; Oxidation-Reduction; Thiazoles; Tumor Cells, Cultured

2003
Enhancement of BRCA1 gene expression by the peroxisome proliferator-activated receptor gamma in the MCF-7 breast cancer cell line.
    Oncogene, 2003, Aug-21, Volume: 22, Issue:35

    Topics: BRCA1 Protein; Breast Neoplasms; Female; Genetic Predisposition to Disease; Humans; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

2003
Enhanced cytotoxicity and nuclear accumulation of doxorubicin-loaded nanospheres in human breast cancer MCF7 cells expressing MRP1.
    International journal of oncology, 2003, Volume: 23, Issue:4

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Coloring Agents; Doxorubicin; Flow Cytometry; Humans; Inhibitory Concentration 50; Microscopy, Confocal; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenotype; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors

2003
AZETEPA (NSC-64826) IN STAGE IV BREAST CANCER.
    Cancer chemotherapy reports, 1964, Volume: 43

    Topics: Alkylating Agents; Amides; Antineoplastic Agents; Azirines; Biomedical Research; Breast Neoplasms; Drug Therapy; Heterocyclic Compounds; Humans; Neoplasms; Phosphinic Acids; Thiazoles; Toxicology

1964
Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:10

    Topics: Annexin A5; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Chromatin; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Deoxycytidine; Detergents; Docetaxel; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Epothilones; Flow Cytometry; Gemcitabine; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Multienzyme Complexes; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Sepharose; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors; Trastuzumab

2003
Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor.
    Nature medicine, 2004, Volume: 10, Issue:1

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; Base Sequence; Benzamides; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; DNA Primers; DNA, Neoplasm; Estrogen Receptor Modulators; Humans; Thiazoles; Transcriptional Activation; Zinc Fingers

2004
In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jan-15, Volume: 10, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Calcimycin; Cell Line, Tumor; Coloring Agents; Doxorubicin; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Ionophores; Ions; Lipid Metabolism; Liposomes; Manganese; Manganese Compounds; Mice; Mice, SCID; Neoplasm Transplantation; Protons; Sulfates; Tetrazolium Salts; Thiazoles; Time Factors; Vincristine

2004
Synthesis and evaluation of substituted 4-aryloxy- and 4-arylsulfanyl-phenyl-2-aminothiazoles as inhibitors of human breast cancer cell proliferation.
    Bioorganic & medicinal chemistry, 2004, Mar-01, Volume: 12, Issue:5

    Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Estrogens; Female; Humans; Inhibitory Concentration 50; Structure-Activity Relationship; Thiazoles

2004
COX inhibitors modulate bFGF-induced cell survival in MCF-7 breast cancer cells.
    Journal of cellular biochemistry, 2004, Mar-01, Volume: 91, Issue:4

    Topics: Apoptosis; Aspirin; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Division; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase 2; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytoprotection; Fibroblast Growth Factor 2; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Isoenzymes; MAP Kinase Signaling System; Meloxicam; Membrane Proteins; Microtubule-Associated Proteins; Mitochondria; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-bcl-2; Survivin; Thiazines; Thiazoles

2004
Differential regulation of signal transduction pathways in wild type and mutated p53 breast cancer epithelial cells by copper and zinc.
    Archives of biochemistry and biophysics, 2004, Mar-15, Volume: 423, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Chromones; Copper; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins; Signal Transduction; Thiazoles; Tumor Suppressor Protein p53; Zinc

2004
A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth.
    Oncogene, 2004, Jun-03, Volume: 23, Issue:26

    Topics: Animals; bcl-X Protein; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Genetic Techniques; Genetic Vectors; Humans; Mammary Neoplasms, Experimental; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Neoplasm Metastasis; Proto-Oncogene Proteins c-bcl-2; Thiazoles; Thiazolidines

2004
Treatment of HER-2/neu overexpressing breast cancer xenograft models with trastuzumab (Herceptin) and gefitinib (ZD1839): drug combination effects on tumor growth, HER-2/neu and epidermal growth factor receptor expression, and viable hypoxic cell fraction
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; ErbB Receptors; Female; Flow Cytometry; Gefitinib; Humans; Hypoxia; Mammary Neoplasms, Animal; Mice; Mice, SCID; Neoplasm Transplantation; Phosphorylation; Quinazolines; Receptor, ErbB-2; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors; Trastuzumab

2004
Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines.
    Cancer research, 2004, May-01, Volume: 64, Issue:9

    Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression; Genes, cdc; Genes, Reporter; Humans; Ligands; Luciferases; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Response Elements; RNA, Messenger; Signal Transduction; Thiazoles; Transcription Factors; Transcriptional Activation

2004
Mifepristone induces growth arrest, caspase activation, and apoptosis of estrogen receptor-expressing, antiestrogen-resistant breast cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: Apoptosis; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA Fragmentation; Drug Resistance, Neoplasm; Enzyme Activation; Estradiol; Estrogen Receptor Modulators; Fulvestrant; G1 Phase; Hormone Antagonists; Humans; Immunoblotting; Mifepristone; Phosphorylation; Receptors, Estrogen; Receptors, Progesterone; Resting Phase, Cell Cycle; Tamoxifen; Tetrazolium Salts; Thiazoles; Time Factors

2004
The experimental antitumor agents Phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models.
    Breast cancer research and treatment, 2004, Volume: 87, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cytochrome P-450 CYP1A1; DNA Adducts; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Prodrugs; Thiazoles; Transplantation, Heterologous

2004
Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, and H4IIE cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 82, Issue:2

    Topics: Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Environmental Pollutants; Female; Humans; L-Lactate Dehydrogenase; Luciferases; Oxazines; Polybrominated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Xanthenes

2004
Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer.
    Oncogene, 2004, Nov-25, Volume: 23, Issue:55

    Topics: Actinin; Adenoviridae; Amino Acid Sequence; Antibodies; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Collagen; Coloring Agents; DNA, Complementary; Down-Regulation; Drug Combinations; Epidermal Growth Factor; Genes, Reporter; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Laminin; Models, Genetic; Molecular Sequence Data; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteoglycans; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection; Two-Hybrid System Techniques; Up-Regulation

2004
RNA expression of human telomerase subunits TR and TERT is differentially affected by melatonin receptor agonists in the MCF-7 tumor cell line.
    Cancer letters, 2004, Dec-08, Volume: 216, Issue:1

    Topics: Acetamides; Breast Neoplasms; Catalytic Domain; Female; Humans; Hypnotics and Sedatives; Melatonin; Receptors, Melatonin; RNA; Signal Transduction; Telomerase; Thiazoles; Thiosemicarbazones; Tumor Cells, Cultured

2004
Breast cancer cells can evade apoptosis-mediated selective killing by a novel small molecule inhibitor of Bcl-2.
    Cancer research, 2004, Nov-01, Volume: 64, Issue:21

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Humans; Proto-Oncogene Proteins c-bcl-2; Receptor, ErbB-2; STAT3 Transcription Factor; Thiazoles; Trans-Activators

2004
Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 83, Issue:2

    Topics: Benz(a)Anthracenes; Benzo(a)pyrene; Benzothiazoles; Breast Neoplasms; Bromodeoxyuridine; Carcinogens; Carcinoma; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Replication; Dose-Response Relationship, Drug; Drug Interactions; Epigenesis, Genetic; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Receptors, Estrogen; Thiazoles; Toluene; Tumor Suppressor Protein p53

2005
Bone marrow stromal cell-derived growth inhibitor inhibits growth and migration of breast cancer cells via induction of cell cycle arrest and apoptosis.
    The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6

    Topics: Amino Acid Sequence; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Blotting, Northern; Blotting, Western; Bone Marrow Cells; Breast Neoplasms; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coloring Agents; Cyclin A; Cyclin-Dependent Kinase Inhibitor p27; DNA, Complementary; Down-Regulation; Gene Library; Genetic Vectors; HeLa Cells; Humans; Molecular Sequence Data; Phylogeny; Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; S Phase; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tetrazolium Salts; Thiazoles; Tissue Distribution; Transfection; Tumor Suppressor Proteins; Up-Regulation; Wound Healing

2005
Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen.
    Molecular pharmacology, 2005, Volume: 67, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzothiazoles; Breast Neoplasms; Drug Resistance, Multiple; Enterocytes; Gene Deletion; Glucuronides; Hyperbilirubinemia; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Mammary Neoplasms, Animal; Mice; Mice, Knockout; Pyridines; Rats; Sulfates; Thiazoles

2005
E2F4 deficiency promotes drug-induced apoptosis.
    Cancer biology & therapy, 2004, Volume: 3, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; E2F4 Transcription Factor; Fibroblasts; Flavonoids; Humans; Lung Neoplasms; Mice; Mice, Knockout; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; RNA, Small Interfering; Roscovitine; Thiazoles; Transcription Factors; Tumor Cells, Cultured

2004
In vitro, in vivo, and in silico analyses of the antitumor activity of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazoles.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:12

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Comet Assay; Computational Biology; Cytochrome P-450 CYP1A1; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Membranes, Artificial; Mice; Mice, Nude; Thiazoles; Time Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2004
Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor: an in vitro study.
    British journal of cancer, 2005, Jan-31, Volume: 92, Issue:2

    Topics: Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cyclohexanones; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Fibroblasts; Humans; Hypoxia; In Vitro Techniques; Neovascularization, Pathologic; Thiazoles

2005
Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines.
    Biochemical and biophysical research communications, 2005, Apr-01, Volume: 329, Issue:1

    Topics: Alkenes; Apoptosis; Blotting, Western; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Nucleus; Cell Survival; Coloring Agents; Cytochromes c; DNA Damage; Dose-Response Relationship, Drug; Genes, Reporter; Humans; Luciferases; Phenols; Plasmids; Receptors, Estrogen; Tetrazolium Salts; Thiazoles

2005
Effects of X-ray irradiation on the overexpression of HER-2/Erb-B2 on breast cancer cell lines.
    Journal of experimental & clinical cancer research : CR, 2004, Volume: 23, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Cell Line, Tumor; Coloring Agents; Dose-Response Relationship, Radiation; Humans; Immunohistochemistry; In Vitro Techniques; Neoplasm Metastasis; Receptor, ErbB-2; Tetrazolium Salts; Thiazoles; Time Factors; Trastuzumab; Trypan Blue; X-Rays

2004
HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Biomarkers; Breast Neoplasms; Camptothecin; Carcinoma; Colonic Neoplasms; Coloring Agents; Drug Interactions; Drug Resistance, Neoplasm; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression Profiling; Humans; Lung Neoplasms; Paclitaxel; Potassium Channels, Voltage-Gated; Tetrazolium Salts; Thiazoles; Transfection; Vincristine

2005
Elucidation of thioredoxin as a molecular target for antitumor quinols.
    Cancer research, 2005, May-01, Volume: 65, Issue:9

    Topics: Amino Acid Sequence; Antineoplastic Agents; Benzothiazoles; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Cyclohexanones; Drug Screening Assays, Antitumor; Humans; Hydroquinones; Insulin; Mass Spectrometry; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Sulfones; Thiazoles; Thioredoxins

2005
Characterization of the activities of actin-affecting drugs on tumor cell migration.
    Toxicology and applied pharmacology, 2006, Feb-15, Volume: 211, Issue:1

    Topics: Actins; Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cytochalasin D; Cytoskeleton; Depsipeptides; Humans; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Invasiveness; Statistics, Nonparametric; Thiazoles; Thiazolidines

2006
Characterizations of irofulven cytotoxicity in combination with cisplatin and oxaliplatin in human colon, breast, and ovarian cancer cells.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:4

    Topics: Algorithms; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Genes, p53; HT29 Cells; Humans; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Sesquiterpenes; Tetrazolium Salts; Thiazoles

2006
Evaluation of reduced toxicity of zearalenone by extrusion processing as measured by the MTT cell proliferation assay.
    Journal of agricultural and food chemistry, 2005, Aug-10, Volume: 53, Issue:16

    Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coloring Agents; Edible Grain; Enzyme-Linked Immunosorbent Assay; Food Handling; Humans; Tetrazolium Salts; Thiazoles; Zearalenone

2005
Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.
    The Journal of biological chemistry, 2005, Dec-02, Volume: 280, Issue:48

    Topics: Acetyltransferases; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Hydrogen Peroxide; Oxidoreductases Acting on CH-NH Group Donors; Peroxisomes; Polyamine Oxidase; Polyamines; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spermine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection

2005
Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha.
    Carcinogenesis, 2006, Volume: 27, Issue:3

    Topics: Apoptosis; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzothiazoles; Breast Neoplasms; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Humans; Leukemia; Macrophages; Microsomes, Liver; Protein Isoforms; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2006
Targeted therapy against Bcl-2-related proteins in breast cancer cells.
    Breast cancer research : BCR, 2005, Volume: 7, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Genes, bcl-2; Humans; Mice; Mice, Nude; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured

2005
Mono(2-ethylhexyl)phthalate and mono-n-butyl phthalate activation of peroxisome proliferator activated-receptors alpha and gamma in breast.
    Toxicology letters, 2006, Jun-01, Volume: 163, Issue:3

    Topics: Breast Neoplasms; Butyrates; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Humans; Phenylurea Compounds; Phthalic Acids; Plasticizers; PPAR alpha; PPAR gamma; PPAR-beta; Statistics, Nonparametric; Thiazoles; Thiazolidinediones; Transfection

2006
Anti-tumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces single-strand breaks and DNA-protein cross-links in sensitive MCF-7 breast cancer cells.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:1

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Thiazoles

2006
Adiponectin induces growth arrest and apoptosis of MDA-MB-231 breast cancer cell.
    Archives of pharmacal research, 2005, Volume: 28, Issue:11

    Topics: Adiponectin; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Plasmids; Recombinant Proteins; Tetrazolium Salts; Thiazoles

2005
Effects of PPAR and RXR ligands in semaphorin 6B gene expression of human MCF-7 breast cancer cells.
    International journal of oncology, 2006, Volume: 28, Issue:4

    Topics: Alitretinoin; Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromans; Dimerization; Fenofibrate; Gene Expression; HT29 Cells; Humans; K562 Cells; PPAR alpha; PPAR gamma; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Semaphorins; Thiazoles; Thiazolidinediones; Tretinoin; Troglitazone

2006
Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells.
    Neuro endocrinology letters, 2006, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Melatonin; Methotrexate; Mice; Nuclear Receptor Subfamily 1, Group F, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Statistics, Nonparametric; Thiazoles; Thiosemicarbazones

2006
Synthesis, characterization, and biological evaluation of M(I)(CO)3(NNO) complexes (M = Re, 99mTc) conjugated to 2-(4-aminophenyl)benzothiazole as potential breast cancer radiopharmaceuticals.
    Journal of medicinal chemistry, 2006, Sep-07, Volume: 49, Issue:18

    Topics: Animals; Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Cell Line; Cell Line, Tumor; Female; Fibroblasts; Humans; Mice; Organometallic Compounds; Radiopharmaceuticals; Rhenium; Structure-Activity Relationship; Technetium; Thiazoles; Tomography, Emission-Computed, Single-Photon

2006
Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer.
    Bioorganic & medicinal chemistry letters, 2007, Jan-15, Volume: 17, Issue:2

    Topics: Adult; Anilides; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Drug Design; Female; Humans; Indicators and Reagents; Isotope Labeling; Nitrobenzenes; Positron-Emission Tomography; Radiopharmaceuticals; Sulfonamides; Tetrazolium Salts; Thiazoles

2007
Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Jan-22, Volume: 117, Issue:1

    Topics: Aminoglutethimide; Antineoplastic Agents; Apoptosis; beta-Cyclodextrins; Breast Neoplasms; Cell Survival; Chlorpromazine; Cytochalasin B; Doxorubicin; Endocytosis; Female; Flow Cytometry; Humans; Immunohistochemistry; Ki-67 Antigen; Kinetics; Liver; Lysosomes; Methacrylates; Microscopy, Confocal; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles

2007
Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro.
    Breast cancer research and treatment, 2007, Volume: 105, Issue:3

    Topics: Administration, Oral; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dasatinib; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Keratins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Sensitivity and Specificity; src-Family Kinases; Thiazoles; Vimentin

2007
Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection.
    Cancer research, 2007, Mar-01, Volume: 67, Issue:5

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Dasatinib; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Models, Genetic; Patient Selection; Prognosis; Pyrimidines; Thiazoles

2007
Antitumor properties of diastereomeric and geometric analogs of vitamin D3.
    Anti-cancer drugs, 2007, Volume: 18, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Calcitriol; Calcium; Carcinoma, Lewis Lung; CD11b Antigen; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Coloring Agents; Female; Fibroblasts; HL-60 Cells; Humans; Lipopolysaccharide Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pancreatic Neoplasms; Prostatic Neoplasms; Rhodamines; Stereoisomerism; Tetrazolium Salts; Thiazoles

2007
Dasatinib may also inhibit c-Kit in triple negative breast cancer cell lines.
    Breast cancer research and treatment, 2008, Volume: 107, Issue:2

    Topics: Breast Neoplasms; Cell Line, Tumor; Dasatinib; Drug Screening Assays, Antitumor; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Thiazoles

2008
Diminished feedback regulation of proteasome expression and resistance to proteasome inhibitors in breast cancer cells.
    Breast cancer research and treatment, 2008, Volume: 107, Issue:2

    Topics: Apoptosis; Boronic Acids; Bortezomib; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Feedback, Physiological; Humans; Leupeptins; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Temperature; Tetrazolium Salts; Thiazoles

2008
Paradoxical proliferative potential of iron (II) sulphate on cancer cells after the 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay.
    International journal of molecular medicine, 2007, Volume: 19, Issue:6

    Topics: Breast Neoplasms; Carcinoma; Cell Proliferation; Colony-Forming Units Assay; Humans; Iron Compounds; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms; Sulfates; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2007
Potentiation of ICI182,780 (Fulvestrant)-induced estrogen receptor-alpha degradation by the estrogen receptor-related receptor-alpha inverse agonist XCT790.
    The Journal of biological chemistry, 2007, Sep-28, Volume: 282, Issue:39

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Drug Synergism; ERRalpha Estrogen-Related Receptor; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Nitriles; Prognosis; Proteasome Endopeptidase Complex; Receptors, Estrogen; Thiazoles

2007
Potential targeted therapy options in the management of basal cell subtype of breast carcinoma.
    Human pathology, 2007, Volume: 38, Issue:12

    Topics: Albumin-Bound Paclitaxel; Albumins; Antineoplastic Agents; Breast Neoplasms; Caveolin 1; CD146 Antigen; Clinical Trials, Phase III as Topic; Dasatinib; Drug Delivery Systems; Female; Humans; Neoplasms, Basal Cell; Paclitaxel; Proto-Oncogene Proteins c-met; Pyrimidines; Thiazoles

2007
PPARalpha and PPARbeta are differentially affected by ethanol and the ethanol metabolite acetaldehyde in the MCF-7 breast cancer cell line.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 102, Issue:1

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Breast Neoplasms; Cell Line, Tumor; Cyanamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Female; Fomepizole; Gene Expression Regulation, Neoplastic; Humans; PPAR alpha; PPAR-beta; Pyrazoles; RNA, Messenger; Thiazoles; Transcription, Genetic; Transcriptional Activation; Transfection

2008
Aberrant expression of Fra-1 in estrogen receptor-negative breast cancers and suppression of their propagation in vivo by ascochlorin, an antibiotic that inhibits cellular activator protein-1 activity.
    The Journal of antibiotics, 2007, Volume: 60, Issue:11

    Topics: Alkenes; Animals; Antibiotics, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Longevity; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Phenols; Proto-Oncogene Proteins c-fos; Receptors, Estrogen; Survival Analysis; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Xenograft Model Antitumor Assays

2007
BRCA1 modulates sensitivity to 5F-203 by regulating xenobiotic stress-inducible protein levels and EROD activity.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Prodrugs; RNA, Small Interfering; Thiazoles; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases

2008
3-methyl-2-(4-substituted phenyl)-4,5-dihydronaphtho[1,2-c]-pyrazoles: synthesis and in-vitro biological evaluation as antitumour agents.
    Archiv der Pharmazie, 2008, Volume: 341, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Pyrazoles; Structure-Activity Relationship; Thiazoles

2008
Inhibition of tumor cell growth by a human B-cell line.
    Biotherapy (Dordrecht, Netherlands), 1994, Volume: 8, Issue:1

    Topics: Adenocarcinoma; Antigens, CD20; B-Lymphocytes; Breast Neoplasms; Cell Survival; Coloring Agents; Herpesvirus 4, Human; Humans; Immunity, Cellular; Killer Cells, Lymphokine-Activated; Leukemia, Hairy Cell; Lymphocytes, Tumor-Infiltrating; Polymerase Chain Reaction; Receptors, Antigen, B-Cell; Receptors, Interleukin-2; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1994
Synthesis and biological activity of thiazolylindolequinones, analogues of the natural product BE 10988.
    Journal of medicinal chemistry, 1995, Mar-17, Volume: 38, Issue:6

    Topics: Aerobiosis; Animals; Breast Neoplasms; Cell Hypoxia; CHO Cells; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; HeLa Cells; Humans; Indoles; Quinones; Structure-Activity Relationship; Thiazoles; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1995
A possible mechanism for the cytotoxicity of a polyacetylenic alcohol, panaxytriol: inhibition of mitochondrial respiration.
    Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkynes; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Death; Enediynes; Fatty Alcohols; Humans; Microscopy, Electron; Mitochondria; Oxygen; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1995
The identification of drug resistance in ovarian cancer and breast cancer: application of the MTT assay.
    Contributions to gynecology and obstetrics, 1994, Volume: 19

    Topics: Adenocarcinoma; Breast Neoplasms; Colorimetry; Coloring Agents; Drug Resistance; Drug Screening Assays, Antitumor; Feasibility Studies; Female; Humans; Neoplasm Staging; Ovarian Neoplasms; Pilot Projects; Predictive Value of Tests; Prognosis; Tetrazolium Salts; Thiazoles

1994
Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin.
    Journal of medicinal chemistry, 1994, May-27, Volume: 37, Issue:11

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Colonic Neoplasms; ErbB Receptors; Fibroblasts; Genistein; Humans; Hydroxylation; Isoflavones; Mice; Molecular Structure; Protein-Tyrosine Kinases; Quercetin; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured

1994
Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:11

    Topics: Animals; Breast Neoplasms; Cell Count; Formazans; Genistein; Growth Inhibitors; Humans; Isoflavones; Mitochondria; Mitosis; Protein-Tyrosine Kinases; Rhodamines; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1993
Anti-proliferative effects of the arotinoid Ro 40-8757 on human cancer cell lines in vitro.
    British journal of cancer, 1993, Volume: 67, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Cell Survival; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Humans; Kinetics; Lung Neoplasms; Morpholines; Neoplasms; Receptors, Estrogen; Retinoids; Tetrazolium Salts; Thiazoles; Tretinoin; Tumor Cells, Cultured

1993
Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo.
    Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Benzimidazoles; Benzothiazoles; Benzoxazoles; Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Metallothionein 3; Mice; Mice, Nude; Structure-Activity Relationship; Thiazoles; Transplantation, Heterologous

1996
Antitumor activity of paclitaxel against human breast carcinoma xenografts serially transplanted into nude mice.
    Journal of surgical oncology, 1997, Volume: 64, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Coloring Agents; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Mice; Mice, Nude; Mitomycin; Neoplasm Transplantation; Paclitaxel; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured

1997
Cell line specific radiosensitizing effect of zalcitabine (2',3'-dideoxycytidine).
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:2

    Topics: Breast Neoplasms; Cell Cycle; Colonic Neoplasms; Flow Cytometry; Humans; Radiation-Sensitizing Agents; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Zalcitabine

1997
Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines.
    Anti-cancer drugs, 1997, Volume: 8, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Curcumin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Ornithine Decarboxylase; Tetrazolium Salts; Thiazoles

1997
Synthesis and cytotoxic activity of indolyl thiazoles.
    Anti-cancer drugs, 1997, Volume: 8, Issue:5

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Drug Screening Assays, Antitumor; Humans; Indoles; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1997
Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells.
    Molecular pharmacology, 1998, Volume: 53, Issue:1

    Topics: Animals; Antineoplastic Agents; Binding Sites; Breast Neoplasms; Cattle; Cell Division; Colchicine; Cyclopropanes; DNA, Neoplasm; Drug Interactions; G2 Phase; Humans; Mitosis; Models, Chemical; Models, Molecular; Molecular Conformation; Structure-Activity Relationship; Thiazoles; Tubulin; Tumor Cells, Cultured

1998
2-(4-Aminophenyl)benzothiazoles: novel agents with selective profiles of in vitro anti-tumour activity.
    British journal of cancer, 1998, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Carcinoma; Cell Cycle; Colonic Neoplasms; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Estrogens; Female; Growth Inhibitors; Humans; Kidney Neoplasms; Male; Melanoma; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Skin Neoplasms; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured

1998
Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Jul-21, Volume: 95, Issue:15

    Topics: Adenocarcinoma; Animals; Apoptosis; Breast; Breast Neoplasms; Cell Differentiation; Chromans; Genes, bcl-2; Humans; Hypoglycemic Agents; Ligands; Mice; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Troglitazone; Tumor Cells, Cultured

1998
Sensitization effect of L-2-oxothiazolidine-4-carboxylate on tumor cells to melphalan and the role of 5-oxo-L-prolinase in glutathione modulation in tumor cells.
    Biochemical pharmacology, 1998, Sep-15, Volume: 56, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Synergism; Glutathione; Humans; Melphalan; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Tumor Cells, Cultured

1998
Evaluation of in vitro chemosensitivity of antitumor drugs using the MTT assay in fresh human breast cancer.
    Breast cancer research and treatment, 1998, Volume: 49, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Regression Analysis; Tetrazolium Salts; Thiazoles

1998
Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Dec-22, Volume: 95, Issue:26

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Survival; Drug Resistance, Neoplasm; Epothilones; Female; Humans; Lactones; Leukemia P388; Leukemia-Lymphoma, Adult T-Cell; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Structure-Activity Relationship; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured

1998
The effect of the flavonoids, quercetin, myricetin and epicatechin on the growth and enzyme activities of MCF7 human breast cancer cells.
    Chemico-biological interactions, 1998, Nov-27, Volume: 116, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Catechin; Cell Division; Flavonoids; Glutathione; Humans; L-Lactate Dehydrogenase; Neoplasm Proteins; Oxidation-Reduction; Quercetin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1998
Peptide YY inhibits growth of human breast cancer in vitro and in vivo.
    The Journal of surgical research, 1999, Volume: 82, Issue:2

    Topics: Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Cell Survival; Coloring Agents; Cyclic AMP; Female; Humans; Intracellular Membranes; Mice; Mice, Nude; Peptide YY; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1999
Predictive chemotherapy of advanced breast cancer directed by MTT assay in vitro.
    Breast cancer research and treatment, 1999, Volume: 53, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorimetry; Coloring Agents; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Predictive Value of Tests; Prospective Studies; Survival Analysis; Tetrazolium Salts; Thiazoles; Treatment Outcome; Tumor Cells, Cultured

1999
Relationship between size and thiazole orange fluorescence of platelets in patients undergoing high-dose chemotherapy.
    British journal of haematology, 1999, Volume: 106, Issue:1

    Topics: Antineoplastic Agents; Benzothiazoles; Blood Platelets; Breast Neoplasms; Erythrocyte Indices; Female; Flow Cytometry; Fluorescent Dyes; Humans; Quinolines; Thiazoles

1999
Telomerase enzyme activity and RNA expression in adriamycin-resistant human breast carcinoma MCF-7 cells.
    Cancer letters, 1999, Jul-01, Volume: 141, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Carcinoma; Cell Count; Cell Division; Cell Survival; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis, Agar Gel; Female; Fluorouracil; Gene Expression; Humans; Paclitaxel; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Taxoids; Telomerase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1999
Shared antigenic epitopes and pathobiological functions of anti-p185(her2/neu) monoclonal antibodies.
    Experimental and molecular pathology, 1999, Volume: 67, Issue:1

    Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Binding Sites, Antibody; Breast Neoplasms; Cell Transformation, Neoplastic; Cross Reactions; Epitopes; Female; Flow Cytometry; Humans; Immunoenzyme Techniques; Immunoglobulin Variable Region; Male; Mice; Models, Molecular; Prostatic Neoplasms; Rats; Receptor, ErbB-2; Tetrazolium Salts; Thiazoles; Trastuzumab

1999
Peroxisome proliferator-activated receptor gamma activation in human breast cancer.
    International journal of oncology, 1999, Volume: 15, Issue:5

    Topics: Breast Neoplasms; Cell Division; DNA-Binding Proteins; Female; Genes, Reporter; Humans; Hypoglycemic Agents; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Proteins; Retinoid X Receptors; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured

1999
Differential IGF-independent effects of insulin-like growth factor binding proteins (1-6) on apoptosis of breast epithelial cells.
    Journal of cellular biochemistry, 1999, Dec-15, Volume: 75, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Size; Cell Survival; Ceramides; Dose-Response Relationship, Drug; Epithelial Cells; Female; Flow Cytometry; Humans; Insulin-Like Growth Factor Binding Proteins; Ligands; Oligopeptides; Somatomedins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1999
[Predictive chemotherapy of breast cancer directed by MTT assay in vitro].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1997, Volume: 19, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Coloring Agents; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Tetrazolium Salts; Thiazoles

1997
Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives.
    Bioorganic & medicinal chemistry letters, 2000, Mar-06, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Hydroquinones; Oxidation-Reduction; Thiazoles; Tumor Cells, Cultured

2000
Peroxisome proliferator-activated receptor gamma ligands inhibit estrogen biosynthesis in human breast adipose tissue: possible implications for breast cancer therapy.
    Cancer research, 2000, Mar-15, Volume: 60, Issue:6

    Topics: Adipose Tissue; Animals; Aromatase; Aromatase Inhibitors; Binding, Competitive; Breast; Breast Neoplasms; Cell Line; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Estrogens; Female; Gene Expression Regulation, Enzymologic; Humans; Ligands; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Stromal Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone

2000
Modulation of daunorubicin toxicity by liposomal encapsulation and use of specific inhibitors in vitro.
    Toxicology, 2000, Apr-03, Volume: 144, Issue:1-3

    Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Drug Carriers; Drug Compounding; Drug Resistance, Neoplasm; Humans; Liposomes; Rutin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2000
Peptide YY and vitamin E inhibit hormone-sensitive and -insensitive breast cancer cells.
    The Journal of surgical research, 2000, Jun-01, Volume: 91, Issue:1

    Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Cell Survival; Coloring Agents; Female; Humans; Peptide YY; Receptors, Estrogen; Tetrazolium Salts; Thiazoles; Tocopherols; Tumor Cells, Cultured; Vitamin E

2000
Synthesis and cytotoxic activity of thiazolyl indolequinones.
    Anti-cancer drugs, 1999, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; CHO Cells; Cricetinae; Drug Screening Assays, Antitumor; Humans; Indoles; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mass Spectrometry; Quinones; Spectrophotometry, Infrared; Thiazoles; Tumor Cells, Cultured

1999
Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells.
    Cancer research, 2000, Sep-15, Volume: 60, Issue:18

    Topics: Aniline Compounds; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzothiazoles; Breast Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; Isoenzymes; Mixed Function Oxygenases; Protein Binding; Substrate Specificity; Thiazoles; Tumor Cells, Cultured

2000
Effect of low dose irradiation on estrogen receptor level in MCF-7 breast cancer cells.
    International journal of cancer, 2001, Feb-20, Volume: 96, Issue:1

    Topics: Binding Sites; Blotting, Western; Breast Neoplasms; Cell Division; Cell Survival; Coloring Agents; Dose-Response Relationship, Radiation; Electrophoresis, Polyacrylamide Gel; Estradiol; Humans; Immunohistochemistry; Pregnenediones; Protein Binding; Receptors, Estrogen; Receptors, Progesterone; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured

2001
A mathematical model of in vitro cancer cell growth and treatment with the antimitotic agent curacin A.
    Mathematical biosciences, 2001, Volume: 170, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Cyclopropanes; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; Kinetics; Mitosis; Models, Biological; Ovarian Neoplasms; Thiazoles; Tumor Cells, Cultured

2001
Antitumour benzothiazoles. Part 15: The synthesis and physico-chemical properties of 2-(4-aminophenyl)benzothiazole sulfamate salt derivatives.
    Bioorganic & medicinal chemistry letters, 2001, Apr-23, Volume: 11, Issue:8

    Topics: Amines; Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Drug Stability; Enzyme Activators; Female; Guanylate Cyclase; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Platelet Aggregation Inhibitors; Prodrugs; Solubility; Sulfonic Acids; Thiazoles; Tumor Cells, Cultured

2001
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Survival; Colonic Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Female; Humans; Infusions, Parenteral; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Pancreatic Neoplasms; Sarcoma; Thiazoles; Tubulin; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2001
Neoadjuvant chemotherapy in inoperable, locally advanced, and inflammatory breast carcinoma: a pilot study of MTT assay in vitro and outcome analysis of 10 patients.
    American journal of clinical oncology, 2001, Volume: 24, Issue:3

    Topics: Adenocarcinoma; Adult; Breast Neoplasms; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Middle Aged; Neoplasm Staging; Pilot Projects; Tetrazolium Salts; Thiazoles

2001
Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2001, Volume: 49, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Differentiation; Cell Division; Chromans; Female; Humans; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Troglitazone; Tumor Cells, Cultured

2001
Troglitazone inhibits growth of MCF-7 breast carcinoma cells by targeting G1 cell cycle regulators.
    Biochemical and biophysical research communications, 2001, Sep-07, Volume: 286, Issue:5

    Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Cell Separation; Cell Survival; Chromans; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Ethanol; Flow Cytometry; G1 Phase; Humans; Ligands; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Receptors, Cytoplasmic and Nuclear; Retinoblastoma Protein; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Transfection; Troglitazone; Tumor Cells, Cultured

2001
Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2.
    Molecular and cellular biology, 2001, Volume: 21, Issue:19

    Topics: Actins; Apoptosis; bcl-2-Associated X Protein; Breast; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Line, Transformed; Cell Survival; Epithelial Cells; Female; Humans; Mitochondria; Neoplasm Metastasis; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Transport; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Thiazoles; Thiazolidines; Transfection; Tumor Cells, Cultured

2001
Therapeutic effects of viral vector-mediated antiangiogenic gene transfer in malignant ascites.
    Human gene therapy, 2001, Sep-20, Volume: 12, Issue:14

    Topics: Adenoviridae; Angiostatins; Animals; Apoptosis; Ascites; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Division; Cell Movement; Cells, Cultured; Collagen; Coloring Agents; Down-Regulation; Endostatins; Endothelial Growth Factors; Endothelium; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Gene Transfer Techniques; Genetic Vectors; Humans; Immunohistochemistry; Lymphokines; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Peptide Fragments; Plasmids; Plasminogen; Platelet Factor 4; Recombinant Fusion Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Breast Neoplasms; Caspase 3; Caspases; Coloring Agents; Cysteine Proteinase Inhibitors; Cytochrome c Group; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Flavoproteins; Hepatocyte Growth Factor; Humans; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mitochondria; Recombinant Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Up-Regulation

2001
[Compared study on Fura-2/AM assay and MTT assay for screening multidrug resistant modulators].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:6

    Topics: Bepridil; Breast Neoplasms; Calcium Channel Blockers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fura-2; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Verapamil

1997
Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole.
    Molecular pharmacology, 2002, Volume: 61, Issue:1

    Topics: Active Transport, Cell Nucleus; Aniline Compounds; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Benzothiazoles; Biological Transport; Breast Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Humans; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Thiazoles; Transcription, Genetic; Tumor Cells, Cultured

2002
Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Blotting, Western; Breast Neoplasms; Butyrates; Caspase Inhibitors; Cell Cycle; Cell Division; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells.
    Cancer research, 2002, Jan-15, Volume: 62, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Epothilones; Epoxy Compounds; G2 Phase; Humans; Mitochondria; Mitosis; Protein Conformation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Thiazoles; Tumor Cells, Cultured

2002
Regulation of aromatase by nuclear receptors.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Aromatase; Benzoates; Breast Neoplasms; Cholecalciferol; Chromans; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Granulosa Cells; Humans; Ligands; Nicotinic Acids; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; RNA, Messenger; RNA, Neoplasm; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured

2001
Doxycycline induces expression of P glycoprotein in MCF-7 breast carcinoma cells.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:3

    Topics: Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Breast Neoplasms; Calcium Channel Blockers; Cell Survival; Doxycycline; Drug Interactions; Drug Resistance, Multiple; Female; Flow Cytometry; Humans; Immunoblotting; In Situ Hybridization; Lasers; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Verapamil

2002
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity.
    British journal of cancer, 2002, Feb-12, Volume: 86, Issue:4

    Topics: Animals; Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Cell Division; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Retinoic Acid 4-Hydroxylase; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Tretinoin; Tumor Cells, Cultured

2002
Involvement of the mt1 melatonin receptor in human breast cancer.
    Cancer letters, 2002, May-28, Volume: 179, Issue:2

    Topics: Breast Neoplasms; Carbazoles; Cell Division; Dose-Response Relationship, Drug; Humans; Immunoblotting; Luciferases; Melatonin; Nuclear Receptor Subfamily 1, Group F, Member 1; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiosemicarbazones; Trans-Activators; Tumor Cells, Cultured

2002
Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line.
    Molecular and cellular endocrinology, 2002, Feb-25, Volume: 188, Issue:1-2

    Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Ductal, Breast; Carrier Proteins; Cell Division; DNA Primers; Female; Humans; In Situ Hybridization; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured

2002
Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay.
    Planta medica, 2002, Volume: 68, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Breast Neoplasms; Cell Division; Cell Survival; Drug Interactions; Estrogens, Non-Steroidal; Flavonoids; Humans; Isoflavones; Kaempferols; Phytoestrogens; Plant Extracts; Plant Preparations; Plants; Quercetin; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin E

2002
MTT assays allow quick and reliable measurement of the response of human tumour cells to photodynamic therapy.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:8-9

    Topics: Adenocarcinoma; Breast Neoplasms; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Hematoporphyrin Derivative; Hematoporphyrins; Humans; Photochemotherapy; Radiation-Sensitizing Agents; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1992
[Strategy for therapy of malignant ascites using MTT assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Ascitic Fluid; Breast Neoplasms; Cisplatin; Clinical Protocols; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Mitomycin; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1992
[Evaluation of predictability of in vitro SDI assay in comparison with in vivo nude mouse assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:10

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Drug Screening Assays, Antitumor; Fibroblasts; Gastrointestinal Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Predictive Value of Tests; Reproducibility of Results; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1989
Carcinostatic activity of a thiazolidinonylidene-hydrazonothiazolidinone derivative against DMBA-induced mammary carcinomata in female Sprague-Dawley rats.
    Experientia, 1973, Volume: 29, Issue:7

    Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Breast Neoplasms; Carcinoma; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hydrazones; Neoplasms, Experimental; Rats; Thiazoles

1973