thiazoles has been researched along with Bone Cancer in 43 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.33) | 18.7374 |
1990's | 2 (4.65) | 18.2507 |
2000's | 13 (30.23) | 29.6817 |
2010's | 25 (58.14) | 24.3611 |
2020's | 2 (4.65) | 2.80 |
Authors | Studies |
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Dai, G; Liu, G; Song, Q; Zheng, D | 1 |
Cerra, C; Harris, MA; Hawkins, CJ; Miles, MA; Shekhar, TM | 1 |
Rahimnejad Yazdi, A; Torkan, L; Towler, MR; Waldman, SD | 1 |
Dai, G; Deng, S; Gao, T; Guo, W; Yang, J; Yu, L; Zhou, S | 1 |
Chen, Y; Guo, R; He, Q; Li, Y; Zhang, K; Zhong, G | 1 |
Bacon, NJ; Fahey, CE; Kow, K; Milner, RJ; Salute, ME | 1 |
Abraham, J; Bracha, S; Davis, LE; Helfand, SC; Hofmann, NE; Huang, ET; Keller, C; Li, G; Loriaux, MM; Mansoor, A; Marley, K; Mata, JE; Séguin, B; Tyner, JW | 1 |
Carlton, MM; Dirksen, WP; Hildreth, BE; Lanigan, LG; London, CA; Martin, CK; Pillai, SP; Rosol, TJ; Simmons, JK; Toribio, RE; Werbeck, JL | 1 |
Bovée, JV; Briaire-de Bruijn, IH; Gelderblom, H; Herpers, B; van de Water, B; van Oosterwijk, JG; van Ruler, MA | 1 |
Battaglia, S; Blanchard, F; Charrier, C; Gobin, B; Heymann, D; Huin, MB; Lamoureux, F; Lanel, R; Lezot, F; Ory, B; Redini, F | 1 |
Alumkal, JJ; Chin, BB; Deng, X; Doot, RK; Duan, F; Febbo, PG; Hartfeil, D; Herman, B; Higano, CS; Mankoff, DA; Muzi, M; Taplin, ME; Taub, JM; Yu, EY | 1 |
Arlt, MJ; Arras, M; Born, W; Fuchs, B; Husmann, K; Jirkof, P | 1 |
Ballazhi, L; Ibrahimi, I; Imeri, F; Jashari, A; Mikhova, B; Mladenovska, K; Popovski, E | 1 |
Beck, JF; Becker, S; Blümel, L; Blumrich, A; Focke, K; Grauel, D; Hentschel, J; Krämer, OH; Marx, C; Schinkel, S; Sonnemann, J; Wittig, S | 1 |
Aonuma, M; Fukutake, S; Kawato, H; Kitagawa, M; Miyazaki, M; Naito, H; Okayama, T; Seki, T; Soga, T; Sugimoto, Y; Uoto, K; Yoshida, K | 1 |
Gandour-Edwards, R; Holt, R; Rebhun, RB; Shahi, MH; Withers, SS; York, D | 1 |
Dringen, R; Rezwan, K; Shahabi, S; Treccani, L | 1 |
Ammendola, M; De Sarro, G; Gadaleta, CD; Leporini, C; Marech, I; Oakley, C; Ranieri, G; Russo, E; Sacco, R; Sammarco, G | 1 |
Gupte, A; Hawkins, CJ; Miles, MA; Shekhar, TM; Tascone, B; Taylor, S; Walkley, CR | 1 |
Bonnelye, E; Clézardin, P; Le Gall, C | 1 |
Saad, F | 1 |
Brown, LG; Corey, E; Koreckij, T; Nguyen, H; Vessella, RL; Yu, EY | 1 |
Chen, JT; Chen, Q; Deng, YJ; Shi, ZJ; Zhang, JH | 1 |
Araujo, JC; Corn, P; Darnay, BG; Lee, F; Logothetis, CJ; Parikh, NU; Poblenz, A; Starbuck, MW; Thompson, JT | 1 |
Anderson, P; Dawra, N; Emara, MM; Hickman, T; Hu, GF; Ivanov, P; Kedersha, N; Tisdale, S | 1 |
Bi, Y; Chen, L; Gao, JL; Gao, Y; Haydon, RC; He, BC; He, TC; Hu, N; Huang, E; Jiang, W; Kim, SH; Li, M; Liu, X; Luo, J; Luo, Q; Luo, X; Luther, G; Luu, HH; Rastegar, F; Shen, J; Shenaq, D; Shi, Q; Wagner, ER; Wang, L; Yang, K; Zuo, GW | 1 |
Feng, YM; Guo, S; Li, N; Liu, LL; Min, J; Su, HC; Zhang, HL; Zhang, JP | 1 |
Agrawal, S; Araujo, JC; Armstrong, AJ; Braud, EL; Gallick, GE; Logothetis, CJ; Lonberg, M; Mathew, P; Paliwal, P; Posadas, E; Trudel, GC | 1 |
Anderson, HC; Garimella, R; Keighley, J; Pinson, D; Tancabelic, J; Tawfik, O; Templeton, K; Thompson, L; Wang, S | 1 |
Agarwal, N; Sonpavde, G; Sternberg, CN | 1 |
Chan, CM; Haugen, BR; Jing, X; Lim, DJ; Lund, GS; Pike, LA; Sams, SB; Schweppe, RE; Sharma, V; Zhou, Q | 1 |
Gleave, ME; Loriot, Y; Zoubeidi, A | 1 |
Ardito, R; De Santis, V; Falcone, G; Maccauro, G; Muratori, F; Rosa, MA; Sgambato, A | 1 |
Egerbacher, M; Hoelzl, C; Thalhammer, JG; Walter, I; Wolfesberger, B | 1 |
Hosono, K; Ishiguro, N; Naruse, T; Nishida, Y | 1 |
Egerbacher, M; Fertl, G; Hoelzl, C; Reider, GA; Skalicky, M; Thalhammer, JG; Walter, I; Wolfesberger, B | 1 |
Isoe, T; Kobayashi, Y; Kubo, K; Murooka, H; Nishitoba, T; Ohno, H; Shibuya, M; Yoneda, T | 1 |
Jove, R; Keschman, EA; Lee, FY; Letson, GD; Muro-Cacho, C; Pledger, WJ; Shor, AC; Trent, JC | 1 |
Cordero di Montezemolo, L; Crescenzio, N; Doria, A; Fandi, A; Foglia, L; Timeus, F | 1 |
Morishita, H; Tanaka, M; Tomita, K; Tsuchiya, H; Ueda, Y | 1 |
Benassi, MS; Ferrari, C; Gamberi, G; Magagnoli, G; Maltarello, MC; Merli, M; Molendini, L; Picci, P; Ragazzini, P; Sollazzo, MR | 1 |
Alessandra Gobbi, G; Lattanzi, G; Lucarelli, E; Maini, V; Marmiroli, S; Mordenti, M; Picci, P; Reggiani, M; Sangiorgi, L; Scrimieri, F; Zambon Bertoja, A | 1 |
Inoue, H; Ito, S; Kawai, A; Ozaki, T; Sato, J; Tanabe, G | 1 |
5 review(s) available for thiazoles and Bone Cancer
Article | Year |
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Targeting mast cells in gastric cancer with special reference to bone metastases.
Topics: Animals; Antigens, CD34; Benzamides; Benzamidines; Bone and Bones; Bone Neoplasms; Bone Resorption; Disease Progression; Gabexate; Guanidines; Humans; Imatinib Mesylate; Immune System; Mast Cells; Neovascularization, Pathologic; NF-kappa B; Piperidines; Proto-Oncogene Proteins c-kit; Pyridines; Stomach Neoplasms; Thiazoles; Tryptases | 2015 |
Cathepsin K inhibitors as treatment of bone metastasis.
Topics: Azepines; Benzamides; Biphenyl Compounds; Bone Neoplasms; Bone Remodeling; Bone Resorption; Breast Neoplasms; Cathepsin K; Cathepsins; Female; Humans; Male; Osteoclasts; Piperazines; Prostatic Neoplasms; Sulfones; Thiazoles | 2008 |
Src as a therapeutic target in men with prostate cancer and bone metastases.
Topics: Antineoplastic Agents; Benzodioxoles; Bone Neoplasms; Dasatinib; Humans; Male; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Mas; Pyrimidines; Quinazolines; Receptors, Androgen; src-Family Kinases; Thiazoles | 2009 |
Novel molecular targets for the therapy of castration-resistant prostate cancer.
Topics: Abiraterone Acetate; Androstadienes; Anilides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Bone Neoplasms; Cancer Vaccines; Carcinoma; Clinical Trials, Phase III as Topic; Clusterin; Dasatinib; Denosumab; Humans; Ipilimumab; Male; Nitriles; Orchiectomy; Phenylthiohydantoin; Prostatic Neoplasms; Pyridines; Pyrimidines; Quinolines; Quinolones; Radium; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Taxoids; Thiazoles; Tissue Extracts; Treatment Outcome; Vaccines, Synthetic | 2012 |
Targeted therapies in metastatic castration-resistant prostate cancer: beyond the androgen receptor.
Topics: Bone Neoplasms; Cell Proliferation; Cell Survival; Dasatinib; Disease Progression; DNA Repair; Epothilones; Gene Fusion; Humans; Male; Neoplasm Invasiveness; Prostatic Neoplasms; Proto-Oncogene Proteins c-met; Pyrimidines; Receptors, Androgen; Taxoids; Thiazoles | 2012 |
2 trial(s) available for thiazoles and Bone Cancer
Article | Year |
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Castration-resistant prostate cancer bone metastasis response measured by 18F-fluoride PET after treatment with dasatinib and correlation with progression-free survival: results from American College of Radiology Imaging Network 6687.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Bone and Bones; Bone Neoplasms; Dasatinib; Disease-Free Survival; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Neoplasm Metastasis; Positron-Emission Tomography; Prostatic Neoplasms, Castration-Resistant; Protein Kinase Inhibitors; Pyrimidines; Receptors, Androgen; Thiazoles; Tomography, X-Ray Computed; Treatment Outcome | 2015 |
Dasatinib combined with docetaxel for castration-resistant prostate cancer: results from a phase 1-2 study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Castration; Dasatinib; Docetaxel; Drug Administration Schedule; Humans; Male; Maximum Tolerated Dose; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Pyrimidines; Taxoids; Thiazoles | 2012 |
36 other study(ies) available for thiazoles and Bone Cancer
Article | Year |
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Inhibition of the Notch signaling pathway attenuates progression of cell motility, metastasis, and epithelial-to-mesenchymal transition-like phenomena induced by low concentrations of cisplatin in osteosarcoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cisplatin; Diamines; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Osteosarcoma; Receptors, Notch; Signal Transduction; Thiazoles; Xenograft Model Antitumor Assays | 2021 |
The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Osteosarcoma; Thiazoles; Xenograft Model Antitumor Assays | 2021 |
Development of a novel bioactive glass suitable for osteosarcoma-related bone grafts.
Topics: Bone Neoplasms; Bone Substitutes; Borates; Cell Line, Tumor; Cell Proliferation; Gallium; Glass; Humans; Osteoblasts; Osteosarcoma; Powders; Tetrazolium Salts; Thiazoles; Zinc Compounds | 2018 |
Notch pathway inhibition using DAPT, a γ-secretase inhibitor (GSI), enhances the antitumor effect of cisplatin in resistant osteosarcoma.
Topics: Adolescent; Adult; Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Case-Control Studies; Cell Proliferation; Child; Cisplatin; Diamines; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Osteosarcoma; Prognosis; Receptor, Notch1; Signal Transduction; Survival Rate; Thiazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Young Adult | 2019 |
Oestrogen-related receptor alpha mediates chemotherapy resistance of osteosarcoma cells via regulation of ABCB1.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; ERRalpha Estrogen-Related Receptor; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Nitriles; Osteosarcoma; Protein Binding; Receptors, Estrogen; RNA Interference; Sp3 Transcription Factor; Thiazoles | 2019 |
Apoptotic effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine osteosarcoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Dogs; Dose-Response Relationship, Drug; Osteosarcoma; Piperidines; Protein Kinase Inhibitors; Pyridines; Thiazoles; Vascular Endothelial Growth Factor A | 2013 |
A case study of personalized therapy for osteosarcoma.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Dasatinib; Dog Diseases; Dogs; Osteosarcoma; Protein Kinase Inhibitors; Pyrimidines; Radiography; src-Family Kinases; Thiazoles; Time Factors | 2013 |
Combined zoledronic acid and meloxicam reduced bone loss and tumour growth in an orthotopic mouse model of bone-invasive oral squamous cell carcinoma.
Topics: Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Neoplasms; Bone Resorption; Cat Diseases; Cats; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diphosphonates; Disease Models, Animal; Heterografts; Humans; Imidazoles; Male; Meloxicam; Mice; Mice, Nude; Mouth Neoplasms; Neoplasms, Squamous Cell; Random Allocation; Real-Time Polymerase Chain Reaction; RNA, Messenger; Thiazines; Thiazoles; Treatment Outcome; Zoledronic Acid | 2015 |
Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Chondrosarcoma; Dasatinib; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HeLa Cells; Humans; Indoles; Male; MCF-7 Cells; Middle Aged; Mutation; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; Pyrimidines; Signal Transduction; src-Family Kinases; Thiazoles; Tumor Suppressor Protein p53; Young Adult | 2013 |
BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell Line, Tumor; Drug Synergism; Female; Humans; Inhibitory Concentration 50; Male; Mice, Inbred C57BL; Mice, Nude; Osteoblasts; Osteoclasts; Osteosarcoma; Phosphoinositide-3 Kinase Inhibitors; Thiazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Primary tumour growth in an orthotopic osteosarcoma mouse model is not influenced by analgesic treatment with buprenorphine and meloxicam.
Topics: Analgesics, Opioid; Animal Welfare; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Buprenorphine; Disease Models, Animal; Drug Therapy, Combination; Female; Injections; Longevity; Lung Neoplasms; Meloxicam; Mice; Mice, SCID; Osteosarcoma; Pain Management; Thiazines; Thiazoles; Tibia | 2015 |
Potential antiproliferative effect of isoxazolo- and thiazolo coumarin derivatives on breast cancer mediated bone and lung metastases.
Topics: 4-Hydroxycoumarins; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Isoxazoles; Lung Neoplasms; Thiazoles; Time Factors | 2015 |
RETRA exerts anticancer activity in Ewing's sarcoma cells independent of their TP53 status.
Topics: Antineoplastic Agents; Bone Neoplasms; Catechols; Cell Cycle Checkpoints; Cell Proliferation; HCT116 Cells; Humans; Mutation; Sarcoma, Ewing; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2015 |
Discovery of DS-5272 as a promising candidate: A potent and orally active p53-MDM2 interaction inhibitor.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Discovery; Fluorine; Gene Expression; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Binding; Proto-Oncogene Proteins c-mdm2; Pyrrolidines; Sarcoma; Thiazoles; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2015 |
BMI1 is expressed in canine osteosarcoma and contributes to cell growth and chemotherapy resistance.
Topics: Adolescent; Animals; Antineoplastic Agents; Bone Neoplasms; Carboplatin; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dogs; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 2-Ring; Humans; Male; Osteosarcoma; Polycomb Repressive Complex 1; Thiazoles | 2015 |
Utilizing the protein corona around silica nanoparticles for dual drug loading and release.
Topics: Blood Proteins; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Carriers; Humans; Meloxicam; Nanoparticles; Osteosarcoma; Silicon Dioxide; Thiazines; Thiazoles | 2015 |
IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Baculoviral IAP Repeat-Containing 3 Protein; Bone Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Survival; Cyclohexanes; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; HEK293 Cells; Humans; Inhibitor of Apoptosis Proteins; Mice, Knockout; Osteosarcoma; Phenotype; Pyrroles; Receptor-Interacting Protein Serine-Threonine Kinases; Retinoblastoma Protein; Signal Transduction; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Transfection; Triazoles; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases | 2016 |
Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Bone Neoplasms; Cell Line, Tumor; Dasatinib; Docetaxel; Humans; Male; Mice; Mice, SCID; Osteolysis; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Taxoids; Thiazoles; Xenograft Model Antitumor Assays | 2009 |
[MTT assay for detecting osteosarcoma cell apoptosis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Humans; Osteosarcoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2009 |
Dasatinib inhibits both osteoclast activation and prostate cancer PC-3-cell-induced osteoclast formation.
Topics: Adenocarcinoma; Animals; Bone Marrow Cells; Bone Neoplasms; Cell Differentiation; Cell Line, Tumor; Collagen; Dasatinib; Humans; Male; Mice; Mice, Inbred C57BL; Monocytes; Neoplasm Proteins; Osteoclasts; Prostatic Neoplasms; Protein Kinase Inhibitors; Pyrimidines; RANK Ligand; src-Family Kinases; Thiazoles | 2009 |
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly.
Topics: Arsenites; Blotting, Western; Bone Neoplasms; Carrier Proteins; Cells, Cultured; Cytoplasmic Granules; Enzyme Inhibitors; Epoxy Compounds; Eukaryotic Initiation Factor-2; Fluorescent Antibody Technique; Humans; Macrolides; Osteosarcoma; Oxidative Stress; Phosphorylation; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Ribonuclease, Pancreatic; RNA, Messenger; RNA, Small Interfering; RNA, Transfer; Teratogens; Thiazoles; Tumor Cells, Cultured | 2010 |
Lysophosphatidic acid acyltransferase β (LPAATβ) promotes the tumor growth of human osteosarcoma.
Topics: Acyltransferases; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Gene Expression Regulation, Neoplastic; Gentian Violet; Humans; Lipids; Neoplasm Metastasis; Osteosarcoma; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2010 |
Down-regulation of β3-integrin inhibits bone metastasis of small cell lung cancer.
Topics: Apoptosis; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Colony-Forming Units Assay; Drug Combinations; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Integrin beta3; Laminin; Proteoglycans; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Small Cell Lung Carcinoma; Tetrazolium Salts; Thiazoles | 2012 |
Effect of 25-hydroxyvitamin D3 and 1 α,25 dihydroxyvitamin D3 on differentiation and apoptosis of human osteosarcoma cell lines.
Topics: Alkaline Phosphatase; Apoptosis; Bone Density Conservation Agents; Bone Neoplasms; Calcifediol; Calcitriol; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Ki-67 Antigen; Osteocalcin; Osteosarcoma; Pilot Projects; Receptors, Calcitriol; Retinoblastoma Protein; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2012 |
Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dasatinib; Focal Adhesion Kinase 1; Humans; Male; Mice; Mice, Nude; Phosphorylation; Protein Processing, Post-Translational; Pyrimidines; Signal Transduction; src-Family Kinases; Thiazoles; Thyroid Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Acrylic cement added with antiblastics in the treatment of bone metastases. Ultrastructural and in vitro analysis.
Topics: Antineoplastic Agents; Bone Cements; Bone Neoplasms; Cell Division; Cell Survival; Cisplatin; Coloring Agents; Doxorubicin; Drug Carriers; Humans; Methotrexate; Methylmethacrylate; Microscopy, Electron, Scanning; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Antineoplastic effect of the cyclooxygenase inhibitor meloxicam on canine osteosarcoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Bone Neoplasms; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dog Diseases; Dogs; Immunohistochemistry; Meloxicam; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Osteosarcoma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Thiazines; Thiazoles | 2006 |
Meloxicam inhibits osteosarcoma growth, invasiveness and metastasis by COX-2-dependent and independent routes.
Topics: Apoptosis; Blotting, Western; Bone Neoplasms; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression Profiling; Humans; Meloxicam; Osteosarcoma; Reverse Transcriptase Polymerase Chain Reaction; Thiazines; Thiazoles; Tumor Cells, Cultured | 2006 |
In vitro effects of meloxicam with or without doxorubicin on canine osteosarcoma cells.
Topics: Animals; Antibiotics, Antineoplastic; Bone Neoplasms; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Meloxicam; Osteosarcoma; Thiazines; Thiazoles; Tumor Cells, Cultured | 2006 |
A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model.
Topics: Acid Phosphatase; Animals; Bone Neoplasms; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Isoenzymes; Mice; Mice, Transgenic; Osteoclasts; Osteolysis; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Mas; Rats; Rats, Inbred F344; Rats, Nude; Receptor, Macrophage Colony-Stimulating Factor; Tartrate-Resistant Acid Phosphatase; Thiazoles | 2006 |
Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival.
Topics: Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Dasatinib; Enzyme Activation; Humans; Neoplasm Invasiveness; Osteosarcoma; Protein Kinase Inhibitors; Pyrimidines; Rhabdomyosarcoma; Sarcoma, Ewing; Signal Transduction; src-Family Kinases; Thiazoles | 2007 |
In vitro antiproliferative and antimigratory activity of dasatinib in neuroblastoma and Ewing sarcoma cell lines.
Topics: Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dasatinib; Humans; Neuroblastoma; Protein Kinase Inhibitors; Pyrimidines; Sarcoma, Ewing; Thiazoles | 2008 |
Differentiating and antitumor activities of 1 alpha,25-dihydroxyvitamin D3 in vitro and 1 alpha-hydroxyvitamin D3 in vivo on human osteosarcoma.
Topics: Adolescent; Alkaline Phosphatase; Animals; Antineoplastic Agents; Bone Neoplasms; Calcitriol; Cell Transformation, Neoplastic; Cisplatin; Culture Media; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydroxycholecalciferols; Mice; Mice, Nude; Osteocalcin; Osteosarcoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Expression of G1 phase regulators in MG-63 osteosarcoma cell line.
Topics: Apoptosis; Bone Neoplasms; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Humans; Interleukin-6; Osteosarcoma; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Retinoblastoma Protein; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Troglitazione affects survival of human osteosarcoma cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Bone Neoplasms; Cell Count; Cell Division; Cell Survival; Chromans; Humans; Osteosarcoma; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2002 |
[A study of MTT-hybrid assay using human bone and soft tissue tumor cells].
Topics: Antineoplastic Agents; Bone Neoplasms; Drug Screening Assays, Antitumor; Humans; Soft Tissue Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |